LOCUS       DBEJKC010000001       118815 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.001, whole genome shotgun sequence.
ACCESSION   DBEJKC010000001 DBEJKC010000000
VERSION     DBEJKC010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 118815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 118815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..118815
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.001"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            28..390
                     /locus_tag="ACL3G6_000001"
                     /pseudo
     CDS             28..390
                     /locus_tag="ACL3G6_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            925..1617
                     /locus_tag="ACL3G6_000002"
     CDS             925..1617
                     /locus_tag="ACL3G6_000002"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HGR0544611.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1670..4081
                     /locus_tag="ACL3G6_000003"
     CDS             1670..4081
                     /locus_tag="ACL3G6_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGR0544612.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGRI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDEKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4331..5032
                     /locus_tag="ACL3G6_000004"
     CDS             4331..5032
                     /locus_tag="ACL3G6_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0544613.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5034..7742
                     /locus_tag="ACL3G6_000005"
     CDS             5034..7742
                     /locus_tag="ACL3G6_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGR0544614.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGCFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NVFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLAFVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKAL
                     YKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLIAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7838..8329)
                     /gene="tpx"
                     /locus_tag="ACL3G6_000006"
     CDS             complement(7838..8329)
                     /gene="tpx"
                     /locus_tag="ACL3G6_000006"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HGR0544615.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGHDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8452..9381)
                     /gene="psaA"
                     /locus_tag="ACL3G6_000007"
     CDS             complement(8452..9381)
                     /gene="psaA"
                     /locus_tag="ACL3G6_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HGR0544616.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKATTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9413..10261)
                     /locus_tag="ACL3G6_000008"
     CDS             complement(9413..10261)
                     /locus_tag="ACL3G6_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HGR0544617.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10258..10980)
                     /locus_tag="ACL3G6_000009"
     CDS             complement(10258..10980)
                     /locus_tag="ACL3G6_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGR0544618.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            11271..13163
                     /gene="pepO"
                     /locus_tag="ACL3G6_000010"
     CDS             11271..13163
                     /gene="pepO"
                     /locus_tag="ACL3G6_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HGR0544619.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVATVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(13286..13915)
                     /locus_tag="ACL3G6_000011"
     CDS             complement(13286..13915)
                     /locus_tag="ACL3G6_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGR0544620.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            14911..17133
                     /locus_tag="ACL3G6_000012"
     CDS             14911..17133
                     /locus_tag="ACL3G6_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015968 - stringent response [Evidence
                     IEA];
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RelA/SpoT family protein"
                     /protein_id="HGR0544621.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            17163..17606
                     /gene="dtd"
                     /locus_tag="ACL3G6_000013"
     CDS             17163..17606
                     /gene="dtd"
                     /locus_tag="ACL3G6_000013"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HGR0544622.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGVAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGANMQVELVNNGPVTIILDTKKR"
     gene            complement(17645..18060)
                     /locus_tag="ACL3G6_000014"
                     /pseudo
     CDS             complement(17645..18060)
                     /locus_tag="ACL3G6_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            18398..18781
                     /locus_tag="ACL3G6_000015"
     CDS             18398..18781
                     /locus_tag="ACL3G6_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544623.1"
                     /translation="MQKENVRMRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVR
                     EYVPKKERIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEEDVLILLSELQNFFLDVFQ
                     AKRIHRAFCVRLCLKAQFLLSNNDS"
     gene            18962..19261
                     /locus_tag="ACL3G6_000016"
     CDS             18962..19261
                     /locus_tag="ACL3G6_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544624.1"
                     /translation="MNRDVLEFLRTETAEKISLYISEANRLEGDVTLLAPSSQDLEDI
                     KNAMLSNSNLGLKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(19356..19793)
                     /locus_tag="ACL3G6_000017"
     CDS             complement(19356..19793)
                     /locus_tag="ACL3G6_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544625.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLGENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(19895..20560)
                     /locus_tag="ACL3G6_000018"
     CDS             complement(19895..20560)
                     /locus_tag="ACL3G6_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0034257 - nicotinamide riboside
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0034258 - nicotinamide riboside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HGR0544626.1"
                     /translation="MAIASGYLNSRLDKFVDWGPWTALVPFGLISVTNVGISMLSTRF
                     TGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQEGRPN
                     QMSQKQVKLAAIIISIIAFLFAFVTNYIGYEGKMNLLAYVTTIAFALSLIANALNALK
                     LTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVRYIEGNSN
                     KEY"
     gene            complement(20748..21398)
                     /locus_tag="ACL3G6_000019"
     CDS             complement(20748..21398)
                     /locus_tag="ACL3G6_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HGR0544627.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            21510..22352
                     /locus_tag="ACL3G6_000020"
     CDS             21510..22352
                     /locus_tag="ACL3G6_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR0544628.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQENFDRLVTHPPCDIAVY
                     GHIHQQLLRHGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDGKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            22428..22865
                     /locus_tag="ACL3G6_000021"
     CDS             22428..22865
                     /locus_tag="ACL3G6_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HGR0544629.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            22934..23236
                     /locus_tag="ACL3G6_000022"
     CDS             22934..23236
                     /locus_tag="ACL3G6_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544630.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFTFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(23327..24400)
                     /locus_tag="ACL3G6_000023"
     CDS             complement(23327..24400)
                     /locus_tag="ACL3G6_000023"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HGR0544631.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            24556..25233
                     /locus_tag="ACL3G6_000024"
     CDS             24556..25233
                     /locus_tag="ACL3G6_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0544632.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            25226..26200
                     /locus_tag="ACL3G6_000025"
     CDS             25226..26200
                     /locus_tag="ACL3G6_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HGR0544633.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLFLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(26249..28192)
                     /gene="thrS"
                     /locus_tag="ACL3G6_000026"
     CDS             complement(26249..28192)
                     /gene="thrS"
                     /locus_tag="ACL3G6_000026"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HGR0544634.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNIAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVNYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(28250..28573)
                     /locus_tag="ACL3G6_000027"
     CDS             complement(28250..28573)
                     /locus_tag="ACL3G6_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HGR0544635.1"
                     /translation="MELQELVEHSWAIRQAYHELEVKHHDSKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            complement(28830..29197)
                     /locus_tag="ACL3G6_000028"
                     /pseudo
     CDS             complement(28830..29197)
                     /locus_tag="ACL3G6_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397621.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            29438..30068
                     /locus_tag="ACL3G6_000029"
                     /pseudo
     CDS             29438..30068
                     /locus_tag="ACL3G6_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
     gene            30209..30478
                     /gene="rpsO"
                     /locus_tag="ACL3G6_000030"
     CDS             30209..30478
                     /gene="rpsO"
                     /locus_tag="ACL3G6_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HGR0544636.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            31294..31908
                     /locus_tag="ACL3G6_000031"
     CDS             31294..31908
                     /locus_tag="ACL3G6_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HGR0544637.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(32201..32950)
                     /locus_tag="ACL3G6_000032"
     CDS             complement(32201..32950)
                     /locus_tag="ACL3G6_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HGR0544638.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMILKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            33083..35419
                     /locus_tag="ACL3G6_000033"
     CDS             33083..35419
                     /locus_tag="ACL3G6_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGR0544639.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTGQTLPVYGVMMLVFTVIFILTSRYQAKK"
     gene            35520..36197
                     /locus_tag="ACL3G6_000034"
     CDS             35520..36197
                     /locus_tag="ACL3G6_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HGR0544640.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVPHVSK"
     gene            36184..36981
                     /locus_tag="ACL3G6_000035"
     CDS             36184..36981
                     /locus_tag="ACL3G6_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HGR0544641.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            36998..38101
                     /locus_tag="ACL3G6_000036"
     CDS             36998..38101
                     /locus_tag="ACL3G6_000036"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR0544642.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWLSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLSILDQAPANELFPGLQGFDNLLYASGGARVDGHLLVTRL
                     LEASQVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARVTSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            38108..38299
                     /locus_tag="ACL3G6_000037"
     CDS             38108..38299
                     /locus_tag="ACL3G6_000037"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544643.1"
                     /translation="MKIKEQTRKLAADYSKHCFEVVDRTDEVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFELDFRRV"
     gene            38402..39421
                     /gene="galE"
                     /locus_tag="ACL3G6_000038"
     CDS             38402..39421
                     /gene="galE"
                     /locus_tag="ACL3G6_000038"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGR0544644.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGIIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            39423..40388
                     /locus_tag="ACL3G6_000039"
     CDS             39423..40388
                     /locus_tag="ACL3G6_000039"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0544645.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(40439..40645)
                     /locus_tag="ACL3G6_000040"
     CDS             complement(40439..40645)
                     /locus_tag="ACL3G6_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HGR0544646.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            40697..41173
                     /locus_tag="ACL3G6_000041"
     CDS             40697..41173
                     /locus_tag="ACL3G6_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HGR0544647.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            41182..41853
                     /gene="cmk"
                     /locus_tag="ACL3G6_000042"
     CDS             41182..41853
                     /gene="cmk"
                     /locus_tag="ACL3G6_000042"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HGR0544648.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            41983..42321
                     /locus_tag="ACL3G6_000043"
     CDS             41983..42321
                     /locus_tag="ACL3G6_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HGR0544649.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIHIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            42324..42953
                     /locus_tag="ACL3G6_000044"
     CDS             42324..42953
                     /locus_tag="ACL3G6_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HGR0544650.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            43193..44344
                     /locus_tag="ACL3G6_000045"
     CDS             43193..44344
                     /locus_tag="ACL3G6_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0544651.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGARLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            44662..45411
                     /gene="truA"
                     /locus_tag="ACL3G6_000046"
     CDS             44662..45411
                     /gene="truA"
                     /locus_tag="ACL3G6_000046"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HGR0544652.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQIDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            45401..46174
                     /locus_tag="ACL3G6_000047"
     CDS             45401..46174
                     /locus_tag="ACL3G6_000047"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGR0544653.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            46152..46613
                     /locus_tag="ACL3G6_000048"
     CDS             46152..46613
                     /locus_tag="ACL3G6_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0544654.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            complement(46872..47120)
                     /locus_tag="ACL3G6_000049"
     CDS             complement(46872..47120)
                     /locus_tag="ACL3G6_000049"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0544655.1"
                     /translation="MASTSLQAPAKICFILIKLYSPYAFLSKYLGAILLSFFCYYAKE
                     IGCNNLTLSVWNDNEGALRFYQRQGMKPQETTMEMIID"
     gene            complement(47068..48150)
                     /locus_tag="ACL3G6_000050"
     CDS             complement(47068..48150)
                     /locus_tag="ACL3G6_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGR0544656.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(48276..49058)
                     /gene="gatD"
                     /locus_tag="ACL3G6_000051"
     CDS             complement(48276..49058)
                     /gene="gatD"
                     /locus_tag="ACL3G6_000051"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit GatD"
                     /protein_id="HGR0544657.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(49058..50401)
                     /gene="murT"
                     /locus_tag="ACL3G6_000052"
     CDS             complement(49058..50401)
                     /gene="murT"
                     /locus_tag="ACL3G6_000052"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit MurT"
                     /protein_id="HGR0544658.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGTYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDVQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(50500..51816)
                     /locus_tag="ACL3G6_000053"
     CDS             complement(50500..51816)
                     /locus_tag="ACL3G6_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HGR0544659.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQNLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDINGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            52009..53235
                     /locus_tag="ACL3G6_000054"
     CDS             52009..53235
                     /locus_tag="ACL3G6_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HGR0544660.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYILWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            53434..55008
                     /locus_tag="ACL3G6_000055"
     CDS             53434..55008
                     /locus_tag="ACL3G6_000055"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0544661.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            55272..56060
                     /gene="codY"
                     /locus_tag="ACL3G6_000056"
     CDS             55272..56060
                     /gene="codY"
                     /locus_tag="ACL3G6_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HGR0544662.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            56060..56635
                     /locus_tag="ACL3G6_000057"
     CDS             56060..56635
                     /locus_tag="ACL3G6_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGR0544663.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDFFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            56717..56802
                     /locus_tag="ACL3G6_000058"
     tRNA            56717..56802
                     /locus_tag="ACL3G6_000058"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:56751..56753,aa:Leu,seq:aag)
     gene            57085..58215
                     /locus_tag="ACL3G6_000059"
     CDS             57085..58215
                     /locus_tag="ACL3G6_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0544664.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            58714..59472
                     /locus_tag="ACL3G6_000060"
     CDS             58714..59472
                     /locus_tag="ACL3G6_000060"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0544665.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            59560..60072
                     /locus_tag="ACL3G6_000061"
     CDS             59560..60072
                     /locus_tag="ACL3G6_000061"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HGR0544666.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            60254..61198
                     /gene="metA"
                     /locus_tag="ACL3G6_000062"
     CDS             60254..61198
                     /gene="metA"
                     /locus_tag="ACL3G6_000062"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HGR0544667.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            61207..61884
                     /locus_tag="ACL3G6_000063"
     CDS             61207..61884
                     /locus_tag="ACL3G6_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGR0544668.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            61982..62740
                     /gene="tpiA"
                     /locus_tag="ACL3G6_000064"
     CDS             61982..62740
                     /gene="tpiA"
                     /locus_tag="ACL3G6_000064"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HGR0544669.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            62778..64283
                     /gene="lytC"
                     /locus_tag="ACL3G6_000065"
     CDS             62778..64283
                     /gene="lytC"
                     /locus_tag="ACL3G6_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HGR0544670.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRNGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            64779..65297
                     /locus_tag="ACL3G6_000066"
     CDS             64779..65297
                     /locus_tag="ACL3G6_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HGR0544671.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            65427..65933
                     /locus_tag="ACL3G6_000067"
     CDS             65427..65933
                     /locus_tag="ACL3G6_000067"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HGR0544672.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQDQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            65933..66103
                     /locus_tag="ACL3G6_000068"
     CDS             65933..66103
                     /locus_tag="ACL3G6_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544673.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            66135..67367
                     /gene="clpX"
                     /locus_tag="ACL3G6_000069"
     CDS             66135..67367
                     /gene="clpX"
                     /locus_tag="ACL3G6_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HGR0544674.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            67376..67963
                     /gene="yihA"
                     /locus_tag="ACL3G6_000070"
     CDS             67376..67963
                     /gene="yihA"
                     /locus_tag="ACL3G6_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HGR0544675.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            67974..68354
                     /locus_tag="ACL3G6_000071"
     CDS             67974..68354
                     /locus_tag="ACL3G6_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HGR0544676.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            68406..69296
                     /gene="rapZ"
                     /locus_tag="ACL3G6_000072"
     CDS             68406..69296
                     /gene="rapZ"
                     /locus_tag="ACL3G6_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HGR0544677.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            69293..70270
                     /locus_tag="ACL3G6_000073"
     CDS             69293..70270
                     /locus_tag="ACL3G6_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HGR0544678.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDFRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            70267..71178
                     /gene="whiA"
                     /locus_tag="ACL3G6_000074"
     CDS             70267..71178
                     /gene="whiA"
                     /locus_tag="ACL3G6_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HGR0544679.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(71212..72180)
                     /locus_tag="ACL3G6_000075"
     CDS             complement(71212..72180)
                     /locus_tag="ACL3G6_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR0544680.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELESVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            72316..73173
                     /gene="cdaA"
                     /locus_tag="ACL3G6_000076"
     CDS             72316..73173
                     /gene="cdaA"
                     /locus_tag="ACL3G6_000076"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HGR0544681.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYMSTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            73160..73939
                     /locus_tag="ACL3G6_000077"
     CDS             73160..73939
                     /locus_tag="ACL3G6_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HGR0544682.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            73963..75315
                     /gene="glmM"
                     /locus_tag="ACL3G6_000078"
     CDS             73963..75315
                     /gene="glmM"
                     /locus_tag="ACL3G6_000078"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HGR0544683.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGNIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            75389..75763
                     /locus_tag="ACL3G6_000079"
     CDS             75389..75763
                     /locus_tag="ACL3G6_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HGR0544684.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            75765..76613
                     /locus_tag="ACL3G6_000080"
     CDS             75765..76613
                     /locus_tag="ACL3G6_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR0544685.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            76890..77657
                     /gene="dapB"
                     /locus_tag="ACL3G6_000081"
     CDS             76890..77657
                     /gene="dapB"
                     /locus_tag="ACL3G6_000081"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HGR0544686.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMHIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            77654..78853
                     /locus_tag="ACL3G6_000082"
     CDS             77654..78853
                     /locus_tag="ACL3G6_000082"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HGR0544687.1"
                     /translation="MRLTQMPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHNPIH
                     DVDIATSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSA
                     VSFVRSLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDA
                     LRIMRGFRFQASLGFALEPETFKAMKTLTPLLENISVERTFVEFDKLLLAPFWRRGLA
                     SMIESQAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKS
                     WKTSRQFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAI
                     TEKYQSLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIH
                     AYLREKK"
     gene            78850..80721
                     /locus_tag="ACL3G6_000083"
     CDS             78850..80721
                     /locus_tag="ACL3G6_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR0544688.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(80864..82048)
                     /gene="mntE"
                     /locus_tag="ACL3G6_000084"
     CDS             complement(80864..82048)
                     /gene="mntE"
                     /locus_tag="ACL3G6_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HGR0544689.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLATGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            82352..85048
                     /locus_tag="ACL3G6_000085"
     CDS             82352..85048
                     /locus_tag="ACL3G6_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGR0544690.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSVDLATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            85061..85852
                     /gene="yghU"
                     /locus_tag="ACL3G6_000086"
     CDS             85061..85852
                     /gene="yghU"
                     /locus_tag="ACL3G6_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HGR0544691.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRQTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTEDVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QENLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            85968..86378
                     /locus_tag="ACL3G6_000087"
     CDS             85968..86378
                     /locus_tag="ACL3G6_000087"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGR0544692.1"
                     /translation="MEKKIVKDNLFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            86390..87985
                     /locus_tag="ACL3G6_000088"
     CDS             86390..87985
                     /locus_tag="ACL3G6_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544693.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            88152..88316
                     /locus_tag="ACL3G6_000089"
     CDS             88152..88316
                     /locus_tag="ACL3G6_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HGR0544694.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            88395..89123
                     /gene="yaaA"
                     /locus_tag="ACL3G6_000090"
     CDS             88395..89123
                     /gene="yaaA"
                     /locus_tag="ACL3G6_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HGR0544695.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(89401..89949)
                     /locus_tag="ACL3G6_000091"
     CDS             complement(89401..89949)
                     /locus_tag="ACL3G6_000091"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGR0544696.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALASKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            90270..90779
                     /locus_tag="ACL3G6_000092"
     CDS             90270..90779
                     /locus_tag="ACL3G6_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HGR0544697.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISGSFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQVDQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GLWNYPTVF"
     gene            90755..91942
                     /locus_tag="ACL3G6_000093"
     CDS             90755..91942
                     /locus_tag="ACL3G6_000093"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR0544698.1"
                     /translation="MELSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            91935..92300
                     /locus_tag="ACL3G6_000094"
     CDS             91935..92300
                     /locus_tag="ACL3G6_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0544699.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            92316..93662
                     /gene="asnS"
                     /locus_tag="ACL3G6_000095"
     CDS             92316..93662
                     /gene="asnS"
                     /locus_tag="ACL3G6_000095"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HGR0544700.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            93815..94105
                     /gene="rpsF"
                     /locus_tag="ACL3G6_000096"
     CDS             93815..94105
                     /gene="rpsF"
                     /locus_tag="ACL3G6_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HGR0544701.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            94117..94587
                     /gene="ssbA"
                     /locus_tag="ACL3G6_000097"
     CDS             94117..94587
                     /gene="ssbA"
                     /locus_tag="ACL3G6_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HGR0544702.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            94619..94858
                     /gene="rpsR"
                     /locus_tag="ACL3G6_000098"
     CDS             94619..94858
                     /gene="rpsR"
                     /locus_tag="ACL3G6_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HGR0544703.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            95153..96553
                     /locus_tag="ACL3G6_000099"
     CDS             95153..96553
                     /locus_tag="ACL3G6_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HGR0544704.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            96555..96914
                     /locus_tag="ACL3G6_000100"
     CDS             96555..96914
                     /locus_tag="ACL3G6_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HGR0544705.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            96968..97717
                     /locus_tag="ACL3G6_000101"
     CDS             96968..97717
                     /locus_tag="ACL3G6_000101"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HGR0544706.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVNPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            97707..98006
                     /locus_tag="ACL3G6_000102"
     CDS             97707..98006
                     /locus_tag="ACL3G6_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGR0544707.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            98077..99012
                     /locus_tag="ACL3G6_000103"
     CDS             98077..99012
                     /locus_tag="ACL3G6_000103"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HGR0544708.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            99098..99610
                     /locus_tag="ACL3G6_000104"
     CDS             99098..99610
                     /locus_tag="ACL3G6_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX/YebB-like N1pC/P60 family cysteine
                     hydrolase"
                     /protein_id="HGR0544709.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAPGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            99594..100243
                     /locus_tag="ACL3G6_000105"
                     /pseudo
     CDS             99594..100243
                     /locus_tag="ACL3G6_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614493.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            100344..100541
                     /locus_tag="ACL3G6_000106"
     CDS             100344..100541
                     /locus_tag="ACL3G6_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGR0544710.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(100584..102029)
                     /locus_tag="ACL3G6_000107"
     CDS             complement(100584..102029)
                     /locus_tag="ACL3G6_000107"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HGR0544711.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQSYLVRRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            102135..103757
                     /locus_tag="ACL3G6_000108"
     CDS             102135..103757
                     /locus_tag="ACL3G6_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGR0544712.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEDSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            103960..105918
                     /locus_tag="ACL3G6_000109"
     CDS             103960..105918
                     /locus_tag="ACL3G6_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0544713.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYRGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            106129..107183
                     /locus_tag="ACL3G6_000110"
                     /pseudo
     CDS             106129..107183
                     /locus_tag="ACL3G6_000110"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            107171..107764
                     /locus_tag="ACL3G6_000111"
     CDS             107171..107764
                     /locus_tag="ACL3G6_000111"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0544714.1"
                     /translation="MRLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVL
                     SGSIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQ
                     RLQIARTYLKDAEILIFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHSLSTVKDV
                     DCIFFLEEGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            107921..109015
                     /locus_tag="ACL3G6_000112"
     CDS             107921..109015
                     /locus_tag="ACL3G6_000112"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGR0544715.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQAIEG"
     gene            109023..110189
                     /locus_tag="ACL3G6_000113"
     CDS             109023..110189
                     /locus_tag="ACL3G6_000113"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HGR0544716.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            110282..113380
                     /locus_tag="ACL3G6_000114"
     CDS             110282..113380
                     /locus_tag="ACL3G6_000114"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0544717.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGLTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            113428..114045
                     /locus_tag="ACL3G6_000115"
     CDS             113428..114045
                     /locus_tag="ACL3G6_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGR0544718.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            114056..115390
                     /gene="murC"
                     /locus_tag="ACL3G6_000116"
     CDS             114056..115390
                     /gene="murC"
                     /locus_tag="ACL3G6_000116"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HGR0544719.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            115400..115864
                     /locus_tag="ACL3G6_000117"
     CDS             115400..115864
                     /locus_tag="ACL3G6_000117"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0544720.1"
                     /translation="MEIPIKIIQASKFDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEEILLYATSQGYSMIWFNPFYLEEQ"
     gene            115861..116355
                     /locus_tag="ACL3G6_000118"
     CDS             115861..116355
                     /locus_tag="ACL3G6_000118"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0544721.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            116436..118091
                     /gene="mltG"
                     /locus_tag="ACL3G6_000119"
     CDS             116436..118091
                     /gene="mltG"
                     /locus_tag="ACL3G6_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HGR0544722.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            118162..118644
                     /gene="greA"
                     /locus_tag="ACL3G6_000120"
     CDS             118162..118644
                     /gene="greA"
                     /locus_tag="ACL3G6_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HGR0544723.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
BASE COUNT        34932 a        22172 c        27052 g        34659 t
ORIGIN      
        1 aaaaaaaata aaaaaggaga ttttattatg aaatcaagtg gtatcgtcgg tcttgtggga
       61 ggaattttac ttcttatttg tccttttgtc ttgttgggaa cagcggtaaa tacagctgct
      121 acaactctta atggaggagc tactgcaggg gctttttcag gtgttgcctt actcttgaat
      181 accttgaaga ttgcaaatct tgttcttggt atcattgcta ttgtttacta taaaggagat
      241 aagcatgtag gtgcagctcc gtctgtacta atgattgttt ctggtgaagt tagtctcatt
      301 ccattcttag gatgagttgg ggggattctt gctattatcg gaggatctct attccttgca
      361 acattgaaga aattcaaatc agaagaataa aaggtatttt agcatgaaaa gaacaaaaaa
      421 gtttatcggt ataggagtag ctctattatc tctttctctt ctagttgcat gtggaacata
      481 aagttcaaag aatacttcaa caagtaatga tgagaagaca gtagcaacat ccaatagttc
      541 aaaagaaaca atcactttcg atacaccggt tgtaacagac gatgcgattg aatcaatacg
      601 cacttatgca gattatatag atctttataa aaatattttt gatgattatt ttactaaagc
      661 tgaggaaggt ttcaaaggca cagttatgga aaataatgac tcgtttacta aactaaaaga
      721 gtcaactcaa aaattattcg atgcgcagaa aaaaaggtta aataatgaag atagaataga
      781 aacagccaaa aacaatgtga ttgccaaaca ttgtcaaaca gtcctttcct ttttggtttt
      841 gactagcttt tttgtgaaaa attgtgtaaa atagaataga taaacgaggg gaaacctcgg
      901 aaaatttaaa ggagaatcca tctaatggta aaattggttt ttgctcgcca cggtgagtct
      961 gaatggaaca aagctaacct tttcactggt tgggctgatg ttgatttgtc tgaaaaaggt
     1021 acacaacaag cgattgacgc tggtaaattg atcaaagaag ctggtatcga atttgaccaa
     1081 gcttacactt cagtattgaa acgtgctatc aaaacaacta acttggctct tgaagcttct
     1141 gaccaattgt gggttccagt tgaaaaatca tggcgcttga acgaacgtca ctacggtggt
     1201 ttgactggta aaaacaaagc tgaagctgct gaacaatttg gtgatgagca agttcacatc
     1261 tggcgtcgtt catacgatgt attgcctcca aatatggacc gtgatgatga gcactcagct
     1321 cacacagacc gtcgttatgc ttcacttgac gactcagtaa tcccagatgc tgaaaacttg
     1381 aaagtgactt tggaacgtgc tcttccattc tgggaagata aaatcgctcc agctcttaaa
     1441 gatggtaaaa acgtattcgt aggagctcac ggtaactcaa tccgtgccct tgtaaaacac
     1501 atcaaaggtt tgtcagatga tgagatcatg gacgtggaaa tccctaactt cccaccattg
     1561 gtattcgaat tcgacgaaaa attgaacgtt gtttctgaat actaccttgg aaaataaaaa
     1621 attgtaagcc taggattgat ttctaggctt tttatgttag tatggaagta tgataaggaa
     1681 taaaaaacaa gattatgtac tggcctacaa acaaccagct tcaaccactt acatgggttg
     1741 ggaagaagaa gctttaccga taggtaatgg ttctttagga gcaaaagtat ttggccgtat
     1801 aggggctgaa cggattcaat ttaatgaaaa aagtctctgg tctggaggtc cacttcctga
     1861 tagttcagat tatcagggtg gaaatcttca ggatcagtat gtttttttag ctgagattcg
     1921 gcaggctttg gagaagagag attacaatct ggctaaggaa ctggctgagc agcacctaat
     1981 tgggccaaaa acgagtcaat atgggaccta tctgtctttt ggggatattc acattgagtt
     2041 cagccagcaa ggtacgactt tgtctcaggt gacggactat cagagacagc tgaatattag
     2101 taaggcactt gtgacgactt cttatgtcta taagggaacg cgatttgaac gtgaagcttt
     2161 tgcgagtttt ccagatgatc tcttggttca gcgttttact aaggaagggg cggaaactct
     2221 agattttact atagaactat ccttgacctg tgatttggct tctgatgaaa agtatgagca
     2281 ggaaaaatct gattacaagg agtgtaagtt ggatattact gattctcata tcttgatgaa
     2341 gggaagagtt aaggataatg atctgcggtt tgctagttat ctagcttggg aaacggatgg
     2401 agatattaga gtttggtcag atagggttca gatatcagga gccagttatg ccaatctctt
     2461 cttggccgct aagacggatt ttgcccaaaa tcctgctagc aattatcgca agaaactaga
     2521 tttagagcaa caggtgatag acttggtgga cacagctaaa gaaaagggct atacccaatt
     2581 gaaatcaagg catatcgagg actaccaagc cttattccag cgtgttcaat tggatttgga
     2641 agctgatgtt gacgcatcca ctacagatga tttgttaaaa aattataagc cacaagaagg
     2701 gcaggctttg gaggagctgt tcttccagta tggacggtat ttattgatta gttcgtccag
     2761 agactgccca gatgctctac cagctaacct acagggagtc tggaatgcgg tcgacaatcc
     2821 tccttggaat tcggactatc acttaaatgt caatctgcag atgaattatt ggccagccta
     2881 tgttaccaat ctcctagagg cggtctttcc ggtcatcaac tatgtagatg atttgcgtgt
     2941 ctatggtcgt ctagcggctg taaagtatgc aggaatcgtc tctcagaaag gtgaggaaaa
     3001 tggttggttg gttcatactc aagcgactcc ctttggttgg acggcacctg gttgggatta
     3061 ctattggggt tggtcaccag ctgccaatgc gtggatgatg caaaccgttt atgaagccta
     3121 ttcattttat agggaccaag actatctcag ggagaaaatt tatcccatgt tgagggaaac
     3181 ggttcgtttt tggaatgcct ttttacataa ggatcagcag gcgcagcgtt gggtgtcttc
     3241 tccgtcttat tctccagaac atgggccgat ttcgattggc aatacctatg accaatctct
     3301 gatttggcag ttatttcatg attttattca ggctgctcag gaattgggac tggatgagga
     3361 cttgttgact gaggttaagg agaagtctga tttactaaat cctttgcaaa tcactcaatc
     3421 tggtcgaatc agggagtggt atgaggagga agagcagtat tttcaaaatg agaaagtgga
     3481 ggcccagcac cggcacgctt cccatctagt gggactctat cctggcaatc tctttagcta
     3541 caagggacaa gagtatattg aagcggcgcg tgctagcctc aatgatcgtg gagatggcgg
     3601 cacaggctgg tccaaggcta ataagatcaa tctctgggcg cgtttgggag atggcaatcg
     3661 agcccataaa ttattggcag agcagttaaa gacatccacc ttgccaaatc tttggtgtag
     3721 ccatcctcct tttcagatag atggtaattt tggtgctact agtggcatgg cagaaatgtt
     3781 actccagtct catgcagctt atctggtacc tctagctgcc ctacctgatg cttggtcaac
     3841 aggttctgtt tcaggcttaa tggcacgtgg acattttgaa gtgagcatga gctgggaaga
     3901 taaaaaactc ttacagttga ccattttatc aaggagtgga ggagatttgc gagtttctta
     3961 tccagatatt gagaagagtg tgattaaaat gaatcaagaa aaaataaaag cgaaatgcat
     4021 ggggaaagat tgtatttcgg tggcaacagc agaaggtgat cttgttcaat tttattttta
     4081 agaagatgtt ataaggcagt aatttgaaac tgccttttaa taaggattta agaatataag
     4141 cagttttcaa ctagttgaaa aagcgttata atgataatag gaagtaatac tcaatgaaaa
     4201 tcaaagagca caaacaagga agctagccgc aggttgctca aaacagtgtt ttgaggttgc
     4261 agatggaagc tgacgtggtt tgaagagaga ttttcgagga gtataatttg tttgatagag
     4321 ggtgggtctg atggcttata ttgagatgaa acactgttac aagcgttatc aggttgggga
     4381 cacggagatt gtggccaatc gtgatgtgaa ttttgagatt gaaaaggggg agctggttat
     4441 tatccttggt gcttcaggtg caggcaagtc aacagtgctt aaccttcttg ggggaatgga
     4501 taccaatgat gaaggggaaa tctggattga tggtgttaat attgcggatt atagttccca
     4561 ccagcgcacc aattaccgta gaaatgatgt ggggtttgtt tttcagtttt ataatctagt
     4621 ttctaatctg acagctaagg aaaatgtgga actggcttct gaaattgtga cagatgcctt
     4681 gaatcctgat caggtcttga cagatgtagg tctggctcat cgtctaaata actttccagc
     4741 ccagctttct ggaggggagc aacagcgagt ctccattgca cgcgcggtag ccaaaaatcc
     4801 taaaattctt ctttgtgatg aacctactgg agccttggat tatcagacgg gcaagcaggt
     4861 tttgaaaatt ctccaagata tgtctcgtca aaagggagcg acggtgatca tcgtgactca
     4921 taatggagct ttggcgccca ttgctgatcg cgtgattcat atgcacgatg ccagtgtcaa
     4981 ggatgtggtg ctcaaccagc atcctcagga tattgacagt ttggagtact agtatgatca
     5041 agcgaaaaac ttattggaag gacttaattc agtccttcac aggctccaag gggtgttttt
     5101 tatccatctt gatcctgatg atgttgggat ctctagcctt agtaggcctc aaagtaacca
     5161 gtcccaacat ggaggcgaca gctaatgctt atttaacaac tgctcaaacc ttggatttgg
     5221 cagtcatgtc taactatggc ttggatcaag cagaccaaga agaactaaaa cagacggagg
     5281 gcgcagaggt cgagtttggc tatttgacag atgtgactat ggataatggg caggatgcca
     5341 ttcggctgta ctccaaacca gagcgaattt caacctttca gctaagaaag ggacgacttc
     5401 ctcagtcaga caaggaaatc gctttggcca ctcatttgca aggccaatac agcgtgggac
     5461 aggagattag ttttaaagaa aaagaagagg gtcattcctc tttaaaagac catacttata
     5521 ccattactgg ttttgtggat tcggctgaaa tcctctccca gcgagatatg ggctacgcag
     5581 gaagtggaag tgggactctg acagcctatg gggtgatttt acctagtcag tttgatcaga
     5641 aagtctacaa tatagctcgt ttgaaatatc aagatttagc aggtttaaat gtcttttcat
     5701 cagcttatga agaaaaatcc aagcaacatc aggaagagct tgaacaaatt ttatcagata
     5761 atggcaaggt acgtctgcaa cttttgaaaa aagaaggaca agagtctcta gacaaggggc
     5821 aagagaccct tgacaaggct cagactaatt tgcaggaagg caagcgtcgt ttagcagctg
     5881 ctcaagctcg tatacaggct caagaaagtc aactagcctt gtttcctcaa gttcagagag
     5941 agcaggctag tgctcaactt acccaagcca agcaggaatt gggcaaggaa gaggacaaac
     6001 taaagcaagc tgaacaaaat ctagcccaag aaaaggaaaa attagaaaaa catcagcaag
     6061 tcttggacga tttggcggag ccaaggtatc aggtctataa tcgtcagacc atgccaggtg
     6121 gtcagggcta tcttatgtat agcaatgctt catccagtat tcgagcagtg ggcaatatct
     6181 ttcctgtggt actttatgcc gtagcagcca tggtgacctt tacgaccatg actcgctttg
     6241 tagacgaaga gcgaactcat gcagggattt ttaaggcctt gggttatcgt agtaaggata
     6301 ttatcgccaa gtttctcctt tatggactag tagctgggac tgtcggaacg gctctaggta
     6361 gtatacttgg tcattatttg ctagccagtg taatttcaag tgtcattaca aaaggcatgg
     6421 tggtgggaga aacccagatt cagttctatt ggacctatag cttactagct tttgtcttga
     6481 gcttgttggc gagtgtgtta ccagcctatc tggtggcttg gagggaactt catgacgaag
     6541 cagcccagct tctacttcct aaacctcctg tcaaaggagc taaaatctta ttggagcgta
     6601 tcggttttat ctggcgtcgt ctcagtttta ctcataaggt aacagcccgc aacatctttc
     6661 gttataagca gagaatgttg atgacaatct ttggtgtggc aggttctgta gctctgctct
     6721 ttgcaggttt gggaatccaa tcttctgtag caggagttcc gtctaaacag tttcaacaaa
     6781 tccaacagta tcagatgctt gtctctgaaa atcctagtgc gaccaatcag gacaaggtag
     6841 agctagcaga agtgttgaaa gggcaggaga tactagccta ccagaaaatc tattctaaag
     6901 cgctatacaa ggatttcaaa ggcaaagctg gtcttcaaaa cattactctt atgatgatag
     6961 agaaggaaga tttgactccc tttatccatc ttcaacatca tcagcaggag ctgacattaa
     7021 aagatggcat cgttattaca gctaaactcg cccagctggc aggtgtcaag gttgggcaga
     7081 ctttagaaat tgaaggtaag gaactaaagg tcgctgctat tactgagaac tacgttggtc
     7141 actttattta tatgagtcag gctagctatg agcaacttta cggacagcta ccccaagcca
     7201 acacttatct ggtctcatta agggatacca gtgcaactag tatcgaaagt caggcgggct
     7261 tgcttatgaa tcaatctgcg gtgtccagcg ttgtccaaaa tgcttcagcc attcgactct
     7321 tcgactctat cgctagctca ctcaatcaga ccatgaccat cttggtcatc gtatcggttc
     7381 tattagctat tgtcatcctt tacaatctga ccaatatcaa cgtagctgag agaatccgtg
     7441 aactctccac tatcaaggtt cttggttttc ataataatga agtcaccctc tacatttacc
     7501 gtgagacgat tgtgctgtcc cttgtgggaa tcgtacttgg tctgatagct ggtttctatt
     7561 tacaccaatt tttgattcaa atgatttcgc ctgcgactat tctcttttat ccgcaggtag
     7621 gctgggaagt ctatgtaatc ccagtggcag cagtaagcat cattttgacc ttgcttggtt
     7681 tcttcgtcaa ttattatctg agaaaggttg atatgttaga agccctgaaa tctgtagagt
     7741 aaggtagtta tttttagctg attgaacttc tatttactaa tattcaaaaa tcctccgttt
     7801 caaagagcag ggaactcttt gtgacagagg attttttcta tagggcttta gcagctgcaa
     7861 ttgcggcttc gaagtttggc tcagaattga tattatccac gtattcaacg tagcgaatcg
     7921 tattgtcagt atcgaggaca aagactgcgc gtgctaatag gtgccattcg ttgatcaaga
     7981 gggcataatc gtgcccgaaa gaatggtcaa agtagtctga aagcataatg gcattgtcaa
     8041 ggccttcagc accgcaccaa cgtttttgag caaaaggtag gtccattgaa acagtcaata
     8101 cgaccgtgtt gtccagtcca gccaattctt cattaaaacg acgtgtttga gttgagcaga
     8161 tgcctgtatc gatagaagga acgacactca agactttttt cttgccatca aaatcagcca
     8221 gagatttttt agaaagatct gttgtagtaa gagaaaaatc aagcgccttg tcgccgactt
     8281 gtagttgttt acctgtaaag ctcacaggat ttccgagaaa agttaccata ggatactcca
     8341 atcttttttc ttccattgta tctgaaacag tcagaatttt ccaatgattt gaccggaaat
     8401 gtgggcatag aaaaaacgcc agctcatatg agaatgacgt ttttcagagg cttattttgc
     8461 caatccttca gcaatcttgt caaggttgta tttcatcatg ctgtagtagc tgtcgccttc
     8521 tttaccttgt tctgcgatag agtcagtaaa gatttgtgcg tagattggga tgtttgtgtc
     8581 ttgagaaacg gttttcattg gacggtcatc cacacttgat tctacaaaga gtgatggaac
     8641 ttttgtttgg cgaagttttt caaccaaggt cttgatttgt tcaggagttc cttcttcttc
     8701 agtattgatt tcccagatgt aggcacttgg aacaccatag gctttagaga agtatttgaa
     8761 tgctccttcg ctggttacaa tgagtttctt ttcagcaggg atcttattaa atttatcctt
     8821 actttcttta tcaagtttgt ctaacttatc agtatattct ttgagatttt tttcatagaa
     8881 ttctttattg ttagggtctt tggcgctcaa ttgtttggcg atatttttag caaaaataat
     8941 accgttttca aggttaagcc aagcgtgtgg gtcttctttt cctttttcat tttgaccttc
     9001 aaggtagata acatcaacgc cgtcgctgac tgcgaagtag tctttgtttt cagttttctt
     9061 ggcattttct accaattttg taaaccaagc attgccacct gtttcaaggt tgataccgtt
     9121 atagaaaatc aaatcagcct cagaagtttt cttaacgtct tcaggaagtg gttcgtattc
     9181 gtgtgggtct tgcccaatcg gaacgatact atgaaggtca attttgtcac cagcaatatt
     9241 tttagtaata tcagcgatga ttgagtttgt agcaacaact tttagttttt gaccagaagt
     9301 tgttgctttt tttccgctag cacatgctac aagaatgatt gcagaaagaa agagaacgag
     9361 taatgtacct aattttttca ttagatcctc caatttatta gggctttgcc ccttatttta
     9421 acaaatgttt atttttcagt ttcaaatatc gttgtttggg agcgataaag aagctaatga
     9481 gaaagaaact agcagctgta agcacgatac tagaacctgc cgcaacatta aaactatagc
     9541 caataaagag tcccaaaact gaagcagtag ctccgaaggt tgaggaaagg aaaatcatgc
     9601 ttttcagact attagcatac agataagcag ttgcagctgg ggtaatcagc atggctacaa
     9661 tcaggatagt tccgacactt tgcatggctg tcacagacac gagagtcagg agtaccatga
     9721 gaaggtagtg atagaaattg acaggcattc ccatggcttt agccaagagt tcatcaaagg
     9781 aagttatcaa gagttgcttg aagaaaatcc agattaacaa gaggatggct gcccccacac
     9841 ccatagtaat aaacatatcc gtatcttgga cggccaggat attaccaaaa aggatatgga
     9901 aaaggtcagt tgaactttta gcgacaccaa tcaagatgat accgagggct aagaaagaag
     9961 aaaaggtaat gccgatggcg gtatcgcttt tgataatcga gtttcctttg atgtaggtaa
    10021 tgatgatggc agctagcaat ccaaagacaa tggctccgat aaagaagtca aggcccaaga
    10081 tgaaggagag ggctacacct ggtaagacag catgtgaaat ggcatctccc atgagtgaca
    10141 tcccgcgtag aataatgaaa catcccacgg ctccagctac aatcccgacg acaatagctg
    10201 ttatcaaggc attttgtagg aaatggaatt tttgcaatcc atcgataaat tctgcaatca
    10261 taggtcacct ccattgaaaa agagttgatt accgtaagct tcttttagat tggtttcggt
    10321 aaaagtttct tttgttggac caaaggcaat cacttctcga ttgacaagta agacttgatc
    10381 gaagtagtgg ggaatcttgc tgaggtcgtg gtgaacgatg agaaccgtct tcccagcttt
    10441 tttcaaatct ctcagcgtat tcatgatgat ttcctcactg acagagtcaa tcccagcaaa
    10501 gggttcatcc aagaggatat agtcggcttc ctgcaccaaa catctggcaa tcaagacccg
    10561 ctggaattga cctccagaca gttgactaat ttgacgttca gcgtagtcag ctaggccgac
    10621 gatttcaagg gcctcttgca ctttcttcca atgtttagcc tttaaacttc gaaagagagg
    10681 aatagaggga aatagtccta acgagacgca ttccttgacc ttgatgggaa agttgtagtc
    10741 gatattgatt ttttgttcga cataggcaat tcggtgtaag gattttttaa cttccttgtc
    10801 atcgagaaat gcctgacctt gatgtgggat aattcccagc atacctttta atagtgttga
    10861 tttcccagcg ccgtttggac caatgatgcc ggtaattgtt ggtccatgga gcactagtga
    10921 aatatcctta agtgccaacg tttctttgta ggagacactg aggttttcga tacgtatcat
    10981 aaacttgtat tcctcctgtc tcttaatata cattaaaaaa aaaattaagt caagttaatt
    11041 tttgaaaaaa ttaaaataat aactgaaaaa tagattctaa agataacttt caggataaat
    11101 ttctaaatta taaaacgcat agtatcaagt gtaaaaaact tggaattatg cgttttatca
    11161 tggaaagatt ttttataata gctaaaaaat aatagttaaa tggttattaa ttgcattccc
    11221 tagtgatttt tgttaagata aatgcaaata caaatgaaag cgagaacaag atgacacgtt
    11281 atcaagatga tttttatgat gctatcaatg gagaatggca acagacagct gaaatcccag
    11341 cagataagtc tcaaactgga ggttttgttg atttagacca ggaaattgaa gacctgatgc
    11401 tggcgacaac agacaagtgg ttagcaggtg aagaagtgcc tgaggatgct atcttggaaa
    11461 actttgtcaa ataccaccgc ctagttcgtg attttgacaa gagagaagct gacggtatca
    11521 cacctgtctt accactcctt aaagaattcc aagaattgga aacttttgcg gattttacag
    11581 ctaaactagc agagtttgag cttgcaggaa aaccaaactt ccttcctttt ggtgtatcgc
    11641 cagactttat ggatgctaga atcaatgttc tatgggctag cgctccaagc acaatcttgc
    11701 cagatacgac ctactatgca gaagaacatc ctcagcgcga agagctcttg actctttgga
    11761 aagaaagcag cgcaaatctc ctcaaggctt atgatttctc tgatgaagaa attgaagact
    11821 tgctagaaaa aagacttgaa ttggaccgcc gagttgcgac agtggtgctc tctaatgaag
    11881 aaagttcaga atatgctaaa ctctatcatc catattctta cgaagatttc aagaaattcg
    11941 cgcctgccct acctttggat gacttcttca aagcagttat tgggcaatta ccagacaagg
    12001 ttattgtaga cgaggaacgt ttctggcaag cagcagagca attctacagt gaggaagcct
    12061 ggtctctcct taaagcaacc ttgattttga gtgttgtcaa tctttcaacc agctatttaa
    12121 cagaggatat ccgtgttttg tctggtgcct acagccgtgc cctttctgga gttccagagg
    12181 caaaagataa ggtcaaagca gcttatcatc tagcacagga acctttcaag caagccctgg
    12241 ggctttggta cgcccgtgag aagttctctc cagaagccaa ggcggatgtg gagaaaaaag
    12301 tggcaaccat gattgatgtc tataaggagc gtctgcttaa gaatgactgg ctcactccag
    12361 aaacctgtaa acaggctatc gtgaagctca atgtgatcaa accttatatt ggctatccag
    12421 aagaattgcc tgcacgttac aaggataagg tagtgaatga aactgccagt ctttttgaga
    12481 atgctctagc ctttgcgcgt gtggaaatca agcacagttg gagtaagtgg aaccagcctg
    12541 tagactataa ggaatggggc atgcctgctc atatggtcaa tgcctactac aatcctcaga
    12601 agaacctgat tgtctttcca gcggccattt tacaggcgcc tttctatgac ttgcatcagt
    12661 catcttctgc taactacggt ggtattgggg cagtgattgc ccatgaaatt tcccacgcct
    12721 ttgatactaa cggggcttcc tttgacgaaa atggtagcct caaggattgg tggacagaga
    12781 gcgactatgc tgccttcaag gagaaaacac aaaaagtcat tgaccaattt gatggacagg
    12841 attcttatgg agcaaccatt aacggtaaat tgactgtatc agaaaacgtg gctgacttgg
    12901 gaggaatcgc agcagcgctt gaagcagcta agagagaagc agacttctca gcagaagagt
    12961 tcttctacaa cttcggtcgc atctggcgca tgaaaggtcg tccagaattt atgaaacttt
    13021 tggctagcgt cgatgtgcac gcaccagcca aactccgtgt caatgtgcaa gtaccaaact
    13081 tcgacgattt ctttacaacc tatgatgtca aagaaggaga cggaatgtgg cgttcaccag
    13141 aggagcgcgt gattatttgg taatacaaaa aatctagtca tcagaaaaaa ggcatccaat
    13201 cacgtgtgaa aaccttgata ggatgccttt tgtaatagaa agatttgctg gatagtttac
    13261 ttaaatttcg attgtcatca tcttgctaga aaaagggatt gaaggccttt tcgtgagcga
    13321 tagtagtagc tggaccatgt cctggataga catcgtagtt tggtagggtg aagagttggg
    13381 tctggatact atgaaggagt tgctccatgc taccagtcgg aaggtcggtc cgtccgatag
    13441 tttcgcggaa tagagcatct cccgtcaaga ctaggtgagc atcaggaaag actagggaaa
    13501 caccaccgat agagtgccct ggggtcggta gaaccttaaa acgaaattcc tctagttggt
    13561 attcttcgtg aaagacaaag gtgtgttctg caggttttgt gaccacatct gccatatcat
    13621 cgtggcgagg gagaccggag agattatcga caggagtgta gagccagctg gcttcgctct
    13681 ctgcgatata gacaggagga ttgccaaacg tctcgcgaac caagtccaga ctcatgatat
    13741 ggtcataatg ggcgtgggtc aagagaatag cacagatcgg tttgttgatc ttctcgattg
    13801 tctgacgaat ggcttcccaa tgactaccag gatcgacgac gatgaggtgc ttttcgcctt
    13861 ctagataata ggtattttca taggcaacag gattcacggt tttatggatt ttcatactag
    13921 ctccaatctc aaagaatgta ctaatactct tcgaaaatct cttcaaaccg cgtcaacttt
    13981 atctgcaacc tcaaagcagt gctttgaaca gcctgcggct agctttctag tttgctcttt
    14041 gattttcatt gagtataaat taagtatagc acagttaggg agaataggta aggatttaaa
    14101 atgaacttaa aaaccagcat gactagatga agacaggctg gttatcaatt tatcaatatt
    14161 ggaaaggtgt caattgccct tcataggttg cataaactcc gtcattagct tgtttgatag
    14221 acgtgatgtt tagagtgcta ccgtagttgg cttctcattt gtcgctatat tcactataag
    14281 ttatcctact gggcaggttc tggtcgttag catagtattg aacgactgtt ttttatagtt
    14341 ttgctggctg aataggaaca ggcagcaaac tcctaacatt aggagagcaa agatagaaat
    14401 agcagttttt ttcataggta ttctccttat aaactaaagg atagaagaaa gtatcttgag
    14461 gatttttata ctcttcaaaa atctcttcaa accgcgtcaa cgtcgccttg ccgtatatat
    14521 gtgactgact ttgtcagtct tatctacaac ctcaaagcag tgctttgaac agcctgcggc
    14581 tagtttccta gtttgctctt ggattttcat tgagtattaa ttccaaaatc cagtcaaggt
    14641 accagtgtat gtgatacgag ttccaccgtt tatctttcgt atcttcaatg gaattgggga
    14701 aatcagaaag tatttgggtt acaatatggt ttccgttctt ctatctctcc ttctatcacc
    14761 taagtttaaa atctaacttc gtagtatatt atgggccaat aattcagaat tatcaagcaa
    14821 ttttgaatta tttttttctt attctgttcc aatctagttt tcatattctt aaaaaagtga
    14881 taaaatggta ggaagaattg gagagtagag atgccgaaag aagtgaattt aacaggcgaa
    14941 gaagttgtcg ctttaaccaa agaatattta acggaagagg atgttcattt tgtccataag
    15001 gccttggtct atgctgttga atgccacagt ggtcaatatc gcaaatcagg cgagccttat
    15061 atcattcacc ctatccaagt ggcaggtatt ttagctaagc taaagctgga tgctgtaaca
    15121 gtagcttgtg gattcttgca tgatgtggtg gaagatacag atgcgacctt ggacgatttg
    15181 gaaagagagt ttggtcctga tgtgcgggtg attgttgacg gagttaccaa gcttggcaag
    15241 gtcgagtaca aatcgatcga ggagcaatta gcggaaaatc atcgcaagat gctcatggcc
    15301 atgtctgagg acatccgcgt tattttggtc aaactgtctg accgcttgca caatatgcgg
    15361 accctgaaac atcttcgaaa agacaagcag gagcgtattt ccaaagaaac catggaaatc
    15421 tatgccccac ttgcccatcg tttggggatt tccagtgtca aatgggaatt agaagacttg
    15481 tctttccgtt atctcaatcc aacggagttt tacaagatta cccatatgat gaaggaaaag
    15541 cgcagggagc gtgaggcctt ggtggatgag gtagtcacaa aattagagga gtatacgaca
    15601 gaacgtcact tgaaagggaa gatttatggt cgtcccaagc atatttactc aattttccgc
    15661 aaaatgcagg acaagagaaa acggtttgag gaaatctatg atctgattgc tattcgttgt
    15721 attttagata cccaaagtga tgtttatgcc atgcttggtt acgtgcatga attttggaaa
    15781 ccgatgccag gtcgcttcaa agactatatt gccaaccgca aggccaatgg ttatcagtct
    15841 atccatacga ctgtttatgg accaaaaggg ccgattgaat tccagattcg aaccaaggaa
    15901 atgcacgagg tggctgagta cggggttgcg gctcactggg cttataagaa aggtataaag
    15961 gggcaagtta acagcaagga atcagctatt ggaatgaact ggatcaagga gatgatggag
    16021 ctccaagacc aggctgatga tgctaaggaa tttgtggact ctgttaagga aaactatttg
    16081 gctgaggaga tttacgtttt taccccagat ggagctgtcc gttcccttcc caaagattca
    16141 ggaccgattg attttgccta cgaaatccat accaaggtcg gtgaaaaagc aactggtgcc
    16201 aaggtcaatg gccgcatggt tccactgaca accaagttaa agacagggga tcaggttgaa
    16261 attatcgcca acccgaactc ctttggacct agccgtgact ggctcaatat ggtcaagact
    16321 agcaaggcgc gcaataagat tcgccagttc tttaaaaacc aagataagga attgtctgtc
    16381 aacaagggtc gtgagatgct gatggctcag ttccaagaaa atggctatgt ggcaaataaa
    16441 tttatggaca agcgccacat ggatcaagtt ctgcaaaaga ccagttacaa gacagaagac
    16501 tccctctttg cggccattgg ttttggggaa atcggtgcga ttaccgtctt taaccgtctg
    16561 actgaaaagg agcgccgtga ggaagagcgt gccaaggcca aggctgaggc agaggagctt
    16621 gtcaaaggtg gcgaggtcaa ggttgaaaat aaagaaactc tcaaggtcaa gcatgagggg
    16681 ggagtggtta ttgaaggtgc ttctggtctc ctagtgcgga ttgctaagtg ttgtaacccc
    16741 gtgcctggtg acgatattgt tggctacatt accaagggtc gtggtgtggc tattcaccgt
    16801 gtggactgta tgaacctgcg tgcccaagaa aactacgagc aacgtctcct tgatgtggaa
    16861 tgggaagacc agtactctag ctcaaataag gagtatatgg cccatatcga tatctacggt
    16921 ctcaaccgta caggactgtt gaacgatgta ctgcaagttc tttcaaatac aaccaagaat
    16981 atttcaacgg tcaatgccca accaaccaag gatatgaagt ttgctaatat ccatgtgtcc
    17041 ttcggtattg ccaacctctc tacactgact acggttgtcg ataaaattaa gagtgtgcca
    17101 gaagtttact ctgtcaaacg gaccaacggc tagttgtcct agctcttact agaaaggcta
    17161 ttatgaaaat cattatccaa cgggttaaaa aagcccaagt gagtatagaa ggccagattc
    17221 agggaaaaat caatcaggga cttttattgc tggttggtgt tggaccagag gaccaagagg
    17281 aagatttgga ctatgctgtg agaaaactgg tcaatatgcg aattttttca gacgcagaag
    17341 gcaagatgaa cctatctgtc aaagatattg aaggagaaat cctctctatt tctcagttta
    17401 ccctctttgc ggatactaag aaaggcaatc gtccagcctt tacaggggta gctaaacctg
    17461 atatggcatc agacttctat gatgctttca atcaaaaatt agcgcaagaa gtgcccgttc
    17521 agacaggtat ctttggagca aatatgcagg ttgagctggt taataacgga cctgttacca
    17581 ttatcctaga tactaaaaag agataagaaa gaccaagccc agtcggcttg gtctttctca
    17641 tctatcataa aatactccaa aaagaaatcg gttcttgata tgcttggggg aagtctcttt
    17701 tcaggctttg gcagatgcga taggaaggga tgagatgtcc taggatgagg agagttccct
    17761 gaaggaaaag tggaatatca cttaaagaca ccaaggagag aatcatcagg ctatcccata
    17821 ggagaatttg taaagcaaaa cgccagaatc tcggtctaat ctgggaatag agttgactaa
    17881 agtggtcaca aagttggttt gaaagatagg tcaatagcac aggatgaaag aaaatgagcc
    17941 aaccgctata aatcaaaatc cagtcccaag taagcccccc tttttaaatg tcaaaaatgc
    18001 cagcatgatt ccatcaatga caaggagttg aatggttttg atgaagatga tttttttcat
    18061 gctaaaacct ccttttcctt agagacactc ccctacaggt attttagaat gtatattgct
    18121 tagatattcc ttattttatt agctttttaa ggtattaaag tagttatata agtttatgaa
    18181 gggtatccta tcctgcacgg ctaattttga gttcgaaact gaggagttta taactcaaaa
    18241 tttcgattaa atcagcattt aacgatagta tgtttgtcat aaaatgataa atttttagat
    18301 tgtggaaatt ttttttaact taattcttga ttttttttct aaatgtgata tacttaattt
    18361 acgggataaa aaaaccacct tagaaaggtg tgataatgtg caaaaagaga atgttagaat
    18421 gcgtttagcg tctgaatcca gacagatatt agataagctt aaagatgatg tttacaataa
    18481 attaggctat gaagtaagct attccagtat tgttagtcaa gctgttagag aatacgttcc
    18541 taaaaaagaa cgtatagatt ggataaaatt aaaagagaca gctataccct tttcatcgtt
    18601 aaaacagagc aataattggg agtaccagac atcacttatg ttagaggaag atgtattaat
    18661 cttactgtct gaactacaaa attttttctt agatgtcttc caagcgaaac gtatacatag
    18721 ggcattttgt gtacgcctat gcttgaaagc acaattttta ttaagtaata atgattctta
    18781 atactatcaa tattaatgcg gagtgtaatg ctccgctaaa ataaaaccta ttacgggata
    18841 aaaacactac tttatttagg atggaaagag gaacgaatga agatgaaagc tagagattca
    18901 ccattgaatt gattttgttt ttagaaaaaa tcaataatta gaaaaaatac gaggtaaaaa
    18961 aatgaataga gatgtattag agtttctgag aacagagacc gctgaaaaaa ttagtcttta
    19021 tataagcgag gctaatagat tggagggcga tgtaactcta ctcgcaccta gttctcaaga
    19081 tttggaagat attaaaaatg ctatgctttc caattctaat ctcggattaa aagttgcgag
    19141 actggatgtg atgaagaaaa tagcatatgc ttctacaaga aatcattatt taacaggggc
    19201 tacgattttt ggggatattt cgaaaggaac atacaattgt gatcctaaaa gttatgtcta
    19261 atataaggga ggttaatccc tccccttgtt tttgaaaatc gaaaggaaaa gtataaaaat
    19321 gaaagttaat gaatatttct ggagaacgag ctgtcttata ctaaaaaaga agaaatcgat
    19381 aaaatagtat acgtgttaga gatgtgtttg tcgtaaaagt ctggatagtt ttctcctagg
    19441 tagtcagctg tcatataata aaaagtagaa tggcaagcag tgataattgg cataagagat
    19501 gaaaaacgct gagaactaat gaaggctaag agaacaaaaa atagaaaatc aatggtgaga
    19561 acccctaaat agtagaagcg aatcttttta ttgatttgag gataaatctc agcgaattga
    19621 tgtttgagtc ggacgaccaa gagaaatagc aggagtcctt gagcaaggaa gaaaattaaa
    19681 ccagagagca agagccactc aaaagatgtc tcgagtctag tgataaaaaa tgcaaatagt
    19741 agcaaatcaa taactgcaat tgctataaaa tggattctat agagtttttt catgacaaga
    19801 ccttcctctt ttatctaact tcattctact ccaaaagaat gggagttaca actaaaatga
    19861 taaaaatagc agaagggaga ttctcttaag ttggctagta ttctttattt gagtttcctt
    19921 ctatgtatct aacttcttca tcattccaga caaataaagc tccgattgca ttgaggatat
    19981 aaaagatgta tttaccgata ttggcgaagt ttccttgaat accagctttt gtcagctgaa
    20041 cgaaattgta aatcaaccaa aagccccact gagttgttag tttcaatgca ttcaaagcat
    20101 tggcaatgag ggacagtgca aaggcaatag ttgttacgta ggcaaggaga ttcatcttgc
    20161 cctcatatcc gatatagttg gtcacaaagg caaagaggaa ggcgatgatg gaaatgatga
    20221 tggccgccaa ttttacctgt ttttggctca tttggttggg tctgccttct tgcgaagctt
    20281 tccatttctt tatagcaaag gtataaatga ggaaggtgac gggataggta atgatggccg
    20341 ccttatttcc aaggatataa tcaatagcac cggacaaaat ggtattaaca ataccaaagt
    20401 aatttcccca tttgcttaat ttccccgtga aacgagtgga caacatggaa atcccaacgt
    20461 tggttacgga aatcaatcca aagggtacaa gagctgtcca tggtccccag tctacaaatt
    20521 tatcgaggcg tgagttgagg taaccagatg caatcgcaat ccaacgacca aagcaacccc
    20581 gaagaggtca aactatttag atgtagcaaa aatttttagt gattttttca taggttaaac
    20641 tacctttctt tttttcaaat attctcccac caaatgaaag taaaataaaa tgatagaaat
    20701 aaaaccctga aaataaaact ttcagggttg gtaggggact tgagaaatta gttgattttc
    20761 tcgacataga gttgttttgc aatgtccata ttcacttgta aatcctcgtc gttactgagg
    20821 atagtgaagg tattgctgaa gccatcaaac tgcttgactt ggagctggtc accgatgtga
    20881 agtgagtgct tgtccagata atggagaatg tcaaaactat cgtgcacccg agtcaggcgg
    20941 taggcgccag cttccttgat atcagctagt gggaggttat tgatttcaac gaggagttct
    21001 cccttggcag gaatagttcc tccgtggggg caggttttag ggaaacctag cagtttatct
    21061 agtctttcca cgaacaggtc agagacagtg tgttccaaga cctcagcttc ctcgtgaatc
    21121 tggtcacttg tatagtctaa atgatgaact agaaaaactt caatcaagcg gtgcttacga
    21181 tagagctcag agaccagttt gagaccgagg tcagtcagta gatagccaca ttccttgtcc
    21241 tttaggatga gattttcact tttcattcgt ttgatcattt cagttacggc agggggagag
    21301 acttgcatgc gagccgcaat ttccttgttg gtaatcttat gcaggtctat gccaatttca
    21361 taaatacatt ttagatagtc ttctttgttt ggggtcattc gtttcctctt gtctaatatc
    21421 tttatctagt atatcaaaaa aagctagatt tctctagctg tgacttttta tgttatactt
    21481 attgcaagag aaaaaacgag gagatggata tgacgaaaat agctcttctt tcagatattc
    21541 atggaaatac caccgccttg gaggctgttt tggcagatgc tcagcagcta ggagtggatg
    21601 aatactggct tttgggagat attctcatgc cagggacagg acgtagaagg attttggact
    21661 tgttggatca actaccgatt acggctagag ttttgggaaa ctgggaagac agtctttggc
    21721 atggtgtccg taaggaattg gatagtactc gccctagtca acgctatctc ttgcgccagt
    21781 gccagtatgt tttagaggaa atttccctag aagaaattga agtgctccac aatcaacctc
    21841 ttcaaattca tcgtcagttt ggggatttga cagtgggaat tagccatcat ctgcctgata
    21901 agaactgggg gcgagagttg attcatactg gcaaacaaga gaattttgac cgcttggtga
    21961 ctcatcctcc ctgtgatatt gctgtttatg gacatattca ccagcagttg cttcgtcacg
    22021 ggactggtgg gcaattgatt gtcaatccgg gttcgattgg ccaacctttc tttttggacg
    22081 ctcagctacg gaaggacttg cgggcccagt atatgatttt ggagtttgat ggcaagggcc
    22141 tggtagatat ggacttccga cgggtagact acgatgtggc agctgaattg cagctggcta
    22201 aagacctgag acttccctat tttgaggttt actatgaaag tctggtcaat gggatccacc
    22261 atactcatca tcaggaattt ttgagagaat tggctcagaa agagggttgc gatcgggagt
    22321 tagacgactg gttgaaaagt ggtaacgatt gacattacaa ctaaaaaggg tataataata
    22381 gaaaaagaag agtagaggca gggtagcctc gtaaaaagga gaagaggatg caaattccaa
    22441 gtagatttac cattgcgact catatgctga taatcattgc cctcgagggg aaggaaagca
    22501 aggtgaccag tgattttctg gctgctagtg tcggggtcaa tcctgtcatt atcagaaaga
    22561 tcttgtccca gttgaagaag gcagagctga tttcagtagc gcgtggaacg ggcggaacag
    22621 agattgtcaa ggaccttaag gatattagtc ttttagatgt ttatcaggcg gtcgaatgtc
    22681 ttggtaagac aggtcaactc ttcagtttcc atgacaatcc gaatccaaat tgccctgtag
    22741 gagctcatat tcatgatgtt ttggatcaaa aattggagag aattcagttg actatggagg
    22801 cagaacttgg tcagaccagt ctagaaaaag tcgtggccga tgcagagagt cagatgaagg
    22861 attaagaggg ataaatgccc tctttttttc tttggataat tatgataaaa tgtagctatt
    22921 aaaggagtaa gaaatgtatc tcgttataga aattgtatta gcctttatag tgtcattttg
    22981 gaaggataat agaagtttgt ggaatccagt attattttta ttatccctca tttcaagtta
    23041 tttttatcta tcctaccttt tttataaaaa tggatacgag aatgttcagt tagcttttta
    23101 tgtatttacc tttgtcttac ttcctttttt gctttttcta agtggcatct ttttaatcta
    23161 taatggggtc attttgttga aacgagaggg acgttccaag ccccattatc tctcaatgct
    23221 ctttgatttt tattgactat tagattctat ttaaaaagac ttagaatgca catgaaagta
    23281 tgtattctag gtcttttgtt ttgtatacat ttaattttca agagtattat ctatttttcc
    23341 atgcatggta acgagtatca atcaataact gggtaaggcg acccaaggtt tctctttctt
    23401 ctggagtgag ggattgagct tggacaaaga gatgatgaat gtattcaagc gcctttaagg
    23461 aagccaagtc attgatagag ctaataccag catcaagaat agtgccaaag aagaggtcga
    23521 agtagagctg aagttcttcg tcagggactg tggccaccca ttctttaaag gttgtgtcta
    23581 cttgccggct atcactgttg gtcttatcca gttgaacgaa gtgcttgtcc tcaatctgcc
    23641 aactaaaggt atcgtgctgg gcgatgccac ccagggcagt actctgaacg atgatttggt
    23701 gagcaggaat ttccagcatc ataccgataa tagacccttg tggaatgaat atcttgcttc
    23761 tatccattat cctttgataa cccgcagtct gtgtcaattc ttgatggaga ccaggtgcat
    23821 caaatgtata aactgctgtg atctgatttt gcaaactttg ctcaatttgg ctagcagcat
    23881 agatagcgag atttcctccc ttggaatgcc cagccagaat aaccttttgc ttaggatgat
    23941 gggcaaaaaa gttctttaaa tagcgaaggg cgtgcttttg agcaggaatt tccttcatat
    24001 aggtcaggtg gaaatcttcc ttccagccaa tgatactgtc atctgtccca cgaaagacaa
    24061 tcagataggt atcgaggctg acacgataag tcatagccgc aaattgcttt tgcagttcag
    24121 ggtcgatgtc gttgataaaa tgggagagtt tgcaattttt gaagcgcttg tgttgagcca
    24181 attcatctaa taattgaagg cgatttttgc tagtaagcat ggtgggctct cttggaacct
    24241 gaggtgctag atctaaaaga cgttgaggaa gtgtggagac cagattatca aaggagaggt
    24301 aggtgatttc tattaaggtt agaatgtcta actcattcaa gggaaggtcg taataagaat
    24361 catatgcgac atctttcaga tagtcaaaaa tattggccat aagagctcct ttctttttat
    24421 ttatcttagc aaatttccct caaattagct agtagcatag cctgtttgta ctggctaaaa
    24481 acaggctatt tcaaattcag tttcagacca tctagcatgg aaaaatctgt tataataatg
    24541 gaaaaggaga agcgcatgca caagatttta ttaatagaag atgatcaggt cattcgtcaa
    24601 cagattggga aaatgctctc tgaatgggga tttgaagtgg tcctggtaga agactttatg
    24661 gaagttttga gtctatttgt tcagtcggaa cctcatctgg tcctcatgga tattggtttg
    24721 cccttgttta atggttatca ctggtgtcag gaaatccgca agatttccaa ggtacctatc
    24781 atgtttcttt cttcgagaga ccaggctatg gatattgtca tggcaatcaa tatgggggcg
    24841 gatgactttg tgaccaagcc ttttgaccag caggttcttt tagctaaggt tcagggcttg
    24901 ttgcgtcgtt cctatgagtt tgggcgtgat gagagtttgc tggaatatgc tggtgttatc
    24961 ctcaatacca aatccatgga tttacattat caagggcaag tcttgaattt gaccaagaat
    25021 gaattccaga ttttacgcgt gttatttgag catgcaggca acatcgtagc acgtgacgac
    25081 ctgatgcggg aactttggaa cagtgacttt ttcattgatg ataataccct ctctgtcaat
    25141 gtggctcgtt tgcgtaaaaa gttggaggag cagggattgg taggatttat cgagaccaag
    25201 aaaggaatag ggtacggatt gaagcatgct tgattggaaa caattttttc tagcctatct
    25261 gcgctcccgt agtcgtcttt ttatctatct gctttttttg gcatttcttg tcttactctt
    25321 tcagttttta tttgccagtc taggaattta cttcctctac tttttcttct tgtgttgctt
    25381 tgtaaccatc ttatttttca cttgggacat attggtggaa acgcaggtct atcgccagga
    25441 acttctctat ggagagaggg aagccaagtc tcctttggaa atagctttag cagaaaaatt
    25501 agaagcgcgt gagatggaac tctatcagca gaggtcaaaa gcagaaagaa aactgacgga
    25561 tttgctggat tactatacct tgtgggttca tcagataaag acccccattg cagccagtca
    25621 actcttagtt gcagaagtgg tcgaccgcca actgaagcag cagctagaac aggaaatttt
    25681 caaaatcgac tcctatacca acctagtttt acagtacctg cgtttagaaa gtttccatga
    25741 tgatttggtc ttaaagcagg ttcaaattga ggacttggtc aaggaaataa ttcgtaaata
    25801 tgctcttttc tttattcaaa aaggcttaaa tgtcaatcta catgaccttg ataaagaaat
    25861 cgtgacggat aaaaagtggc tgctagtggt tattgagcaa atcatctcaa acagtctcaa
    25921 gtacaccaag gaaggtggtc tggagattta tatggatgac caagagcttt gtatcaaaga
    25981 tacgggaatc gggataaaaa acagtgatgt cctccgagta tttgaacgtg gcttttcagg
    26041 atacaatggc cgtttgaccc agcagtcctc tggacttggc ctttatctat ctaagaaaat
    26101 ttctgaagaa ctggggcacc agattcgtat cgagtctgag gtcggaaaag gaacgacagt
    26161 gcggattcag tttgctcaag tgaacttagt ccttgagtaa aaatagatga gaaaaagcct
    26221 ccagattgga ggcttttatg ctagactctt atttctcaac gcgtgatttg ttggcgatat
    26281 cagctaggat agcttgaaca aaattatcaa ctgagacagt ttgtgtttct ttttggccgt
    26341 agcgacgaac gttgactgtt tcgtcttcca tttctttgtc tccaacaatt aattggtaag
    26401 gaatcttgct ggtttgtgaa gcacggatct tgaactgcat tttttcattg cgctcatcta
    26461 cgtctgcacg gacaccgcgg tcacggagtt tcttggccac ttcccaagcg tagttcacgt
    26521 gtttttcgtt agatactggg atgagggtta cttggtgtgg tgccagccat gttgggaagg
    26581 cccccttgta gttctcaatc aagatagctg tgaagcgttc catagttgag ataaccccac
    26641 ggtggatcat gactggacgg tgatcttcgc catcagctcc gatgtatttg aggtcgaagc
    26701 gttctggcaa caagaaatca agttggatag tagaaagggt ttcttctttt ccaagggcag
    26761 ttttaatctg gatatccaat tttggtccgt agaaggctgc ttcaccttcg gcttcaaagt
    26821 agtccacgcc catttcatca agagctgcac gaagcatggt ttgggcattt tcccacatct
    26881 catcgttatc aaagtactta tgagtatctt gagggtcacg aagagagagg cggaagcggt
    26941 agtcagtcaa gttgaagtct tcataaacat cgataatcaa ctgaagggca cgttggaatt
    27001 cttcttggat ttgttctgga gtaacgaata ggtgaccgtc gttgagtgac atttcacgta
    27061 cacgttgaag gccagtgagg gcaccagatt tttcgtaacg gtgcatcata ccgatttcag
    27121 cgatacggat tggcaattca cggtaagagt gaacatggtg tttgaaaact tggatgtggt
    27181 gcggacagtt cattggacga aggacaaatt cttccccgtc acccatgtcc atggttggga
    27241 acatgtcttc ttggtaatga tcccagtgac cagaagtctt gtaaagctca acagaagcaa
    27301 gtggtggagt gtagacgtgt tggtagccag aagccaactc tttgtttacg atgtagcgtt
    27361 ccaattcacg acggatagtc gcaccatttg gcaaccagaa tggcaaacct tgtcccactt
    27421 cttgtgaaat cataaagagg tcaagctctt taccaagttt acggtggtca cgttccttag
    27481 cttcttcacg catttgaagg tagtttttca agtctttctt gtcaaaccaa gctgtaccgt
    27541 agatacgttg catcatagcg ttgtcgctgt ttccacgcca gtaagcacca gctacatgga
    27601 gaaggtggaa gatttggata cgacctgttg atggaacgtg aggtccacgg cagaggtcta
    27661 catattcacc ctgacgatag atagtcaaac cgccttcgtc ttctgagtgt tcttcaatca
    27721 attccaactt gtaagggtca tttttgaaga tttcacgtgc ctcgtcttta gtcacttctt
    27781 cacgaataga tgggaagttt tctttgacga ttttttgcat ttcttcttcg atacgaggaa
    27841 ggtcttcgtt agagatttga ccagctatgt tgtcagtatc gtagtagaaa ccatcttcga
    27901 tggctggacc aactcccaag tgaatgtctg ggaaaagacg acgagctgct tgggcgaaca
    27961 agtgagctgc tgagtgacgc aagattggaa gggcatcttc gtgatcaggt gtcacaattt
    28021 cgatgcttcc atcttcagtg atagcgcgag tagtgtcgat gagtttgccg ttgaatttac
    28081 cagccaaggc ttttttagct agggaattgc tgatagattg ggcaatttca aaagttgtta
    28141 cgccagattc gaattcacga acagcgccat ctgggaaagt aatgttaatc atgatgttct
    28201 ccttttttat tatttcatag tttctaagca ttgatttttt atcagcagac tacttccaag
    28261 tcctaacgtt caattgcttt tctttatcag agaggaagtt ttccatttcc gtcagaatgt
    28321 ctatatccaa acgttgagaa agttctaata gccaccagat attttctgaa agtttttgtt
    28381 ccagtgtgta gggtgtttca tcatagtagc gtccttgctt tgtcatcacc aatcgttgga
    28441 aatttccaat atcattagat aaagccaaga ggtcttcttc taccgtccac ttggaatcat
    28501 gatgcttaac ttccagttcg tgataagctt gtcggattgc ccaactgtgc tccactaatt
    28561 cttgcaactc cataattagt atcctaataa aaaaatgcga catcctcgaa aggacgtcgc
    28621 aacgtggttc caccttcatt tatgtacctc aaaagagagg gacacctctg atcggctcta
    28681 acgtggccac cgttttatgt tttcataaaa aactcaagag tagtatcagt ttagacttcc
    28741 tatgcgtttc cagcaaccac gcactctcta gtagaaaggg actaagtgac ttgtctctat
    28801 ggattattat agcatgattg tgagattttt caaggatttt gtgaaagttt tttgtttttc
    28861 attttttgta gaatatgctt gatgctaata ccagaatcca tgcccaccag agcaactgtt
    28921 tcatagatta gcaagtaaat tagtataaac tcaccaaaga ttatgatagt gaagtaaaag
    28981 agcagtccgt taccaactaa ccatcaaagt gagaaacgga aacggtagct atagagtaac
    29041 gatacaatca agattaccag aggtgtaaag aagagaagat tgtttatata gagtcccttg
    29101 agtgtaaggg ggtcagaaac aactagcaag aacaactcat aaagtggcca ataaatatga
    29161 ccagatagta ggggagatgg gaatagaatc tacgcatgat aatcacctcg ttttaaaaaa
    29221 aacagacaac ttagatctct tgctatgatt attataagca tgtttaaaac aagaaagtaa
    29281 atttgttgac aaagaagatt tttcttttca ctagaatcat agttagtttt cttggtagaa
    29341 atattttgat aataattaag caagactatt gacattgatt attaagagtg tcacaattgc
    29401 tgtaactaaa ataattacaa caagagaggt ataaaaaatg aaactagcag ttattgcagc
    29461 aaatggacaa gtggggaaag caattgttga agaagcagtc aaacgaggac atgaagtaac
    29521 ggctattgtt cgttctgaaa acaaaagtca agctgagtct attattaaaa aagatttatt
    29581 tgagttgaca aaagatgatc ttactggatt tgatgctgtt atttcagcgt ttggtgctta
    29641 tacaccagat acgctaccgc tccatagcaa atcaatcgaa ctatttaatc agcttcttgc
    29701 tggaacacag acacgttttc tagttgtagg gggagcagaa agtctttata tagatgaaac
    29761 aaaaacgaca cgacttttag atacgtctga ttttcctgaa gaatttaagt cactagcaaa
    29821 agctcaagcg gatgaattgg atcttcttcg tacaaaaaat aatctcaact ggacttttgt
    29881 cagtcctgct gtagatttta ttcccgatgg tgaaaaaaca ggaaactaca ttctagcagg
    29941 agaaattttt actactaatg aaaaaaggaa taagccagat tagttatgca gattatgcta
    30001 ttggattggt agatgaactt gaaaaaggtc atcatataaa agaacgtatc tctttacttg
    30061 aaaaataata actatgagag tattaatgtt tgacagaaaa tttaaatctt ggtaaaatag
    30121 ggattgtcgt aaagacaaat aacttcttct tggttacagg catgccaacc tgtcactcgg
    30181 atgaagccaa ataaaaagga gaaacatcat ggcaatctca aaagagaaaa aaaatgaaat
    30241 cattgcacaa tatgcacgtc acgaaggtga tacaggttca gtagaggttc aagttgctgt
    30301 ccttacttgg gaaatcaacc accttaacga acacatcaaa caacacaaaa aagaccacgc
    30361 tacttaccgt ggattgatga aaaaaatcgg tcgtcgtcgt aacttgcttg catacttgcg
    30421 taaaaacgac gttaaccgtt accgtgagtt gatcaactct ctaggacttc gtcgctaatt
    30481 caagatacaa aggccgtcaa aagcacaaag caaaaatagg aaaattgacg aagaaacttc
    30541 agtttctagg agattttatc ttttttgcca agtgcttagg ccgtgttcaa ttgagcatat
    30601 cttgataata aagctactct aaattgggta gcttttttgc gttgtcacct tacctcgcta
    30661 tactcaagta taatctttgg ttacggttcc tagcactgta aggtaaaata aaccagcttt
    30721 tctcccttcg gggagatttt ttttgtttca ctgaaagttt cgtacgatct tcgcctcgtc
    30781 gcctagtcta taaacgattt atctagcaag aatcatgatg ctaagggcgt caaaaatccg
    30841 tatgaaaata gggaaatgac acagtgttcg atgagcacaa ggagtttcat ctttttcact
    30901 aggattttag cccgggctaa aatcagctct ctgacttcag agggcttttt tattgaggtt
    30961 ttatcggtaa caattttgga gactacaaaa acctcaaatg gtatcagcta attacaccat
    31021 aaaggtgcgc agttactcgg cttttcaagc cgagtagctg tatgcaagcc ccctagaaga
    31081 gcccactctt tacaaagtaa agtatagtat gttatacttt acatggaagt agtcactgaa
    31141 ttccagttag aaattacttt gtaactacgt tttgaggagg agtaaaatgc tttcctacgt
    31201 tcgacattac ccactagcga tagctaaatt aatgtgtctg tgctctcctg aaatctgctg
    31261 atttattact gactaataca ggaggttttt tttatgggac agacaatcat atctgctatt
    31321 ggtgtttata tttccaccag tatcgattat ttaattattt taattatttt atttgcacag
    31381 ctatcacaga ataaacagaa atggcatatt tatgcggggc aatatctagg cacaggctta
    31441 cttgtagggg cgagtttagt tgctgcttat gtcgttaatt tcgtgcctga agaatggatg
    31501 gttggattgc ttggtttaat ccctatctat ttagggattc gctttgcaat tgttggagaa
    31561 gatgcggaag aagaagagga agaaattatt gaaagattag aacaaagcaa ggcaaatcaa
    31621 ctgttttgga cagttacatt gctgacaatt gcgtctggcg gagataattt aggtatctat
    31681 ataccttatt ttgcttcgtt agattggtca cagaccctcg tggccttgct tgtgtttgta
    31741 atcggcataa ttatcttttg cgagattagt cgggtgttat cctctattcc gttaatattc
    31801 gagacaattg aaaaatacga gcgaatcatt gtgcccttag tattcattct acttggacta
    31861 tacatcatgt atgaaaatgg cacgatagag acttttctga tcgtgtagat ttttttgttt
    31921 cactaggatt ttagcccgag ctcaaatcag ctctctgatt ttcagagggc tttttcattg
    31981 agtataaatg gacaatctta aagttactct attgtagagt ggcttttgat ttgattagga
    32041 gattcttata aatatagtaa aatgaaacaa aaacaggaca aatcgatcag gacagtcaaa
    32101 tcgatttcta aaaatgtttt aagaagtaga ggtgtactat tctagtttca atttgctata
    32161 taaatgaaaa ccttagctgt ttggccaagg ttcatttctt ctatgcaagt tcttctcttt
    32221 tcttatctgg gttccagatg aagcttgcga taaagctaaa gatgatggtt aggatagcga
    32281 ggataatagc aaggatgagg gcagggatgc ggataaacca ccagagtgga tttggttttt
    32341 tatcattgtg ccattgtttc gtttcttcgt ccagacgttg gaattctgtt tgaatacgat
    32401 tggcgactgt ttcaatgcct tcatcattca ttttcttgat atctgagata tcgattggat
    32461 ttccaaagtt catatcgaca cgttcacggc taatcaagcc cttcaaaatc atgggaccgg
    32521 tgtaggtaac cggcatgata cggaccttgg ccattttggc aatcagtgct gcgcccccct
    32581 tgacatcgtt tgagtggcgg ctaccacttg gaaacatgat gagagagcgg tcactttttt
    32641 tgagaacgtt gataggatat ttgatggctg aggcgctggg attttcacgg tcgatgggaa
    32701 aggcgccaca catacgaatc caccaaccaa agatacggtt ggtaaagagt tctttttttg
    32761 ccataaagat gaactgtttt ggcttggtcg caaaggccat ataaacagga tcccaccagg
    32821 tacggtgagg cgcaactaaa atataatttt catcttgatt aggaatttta tcagtattat
    32881 gatagtgagc attgccattg atggaccata agagcaacac aactaatcca cgcaaataag
    32941 tataaaacat gcgatctcct tcgattgttt tcttgttatt attatacctt atcaaaggag
    33001 ggctggcaaa cttttccctt gactagatgc atatttggga tgaaattaga attctgttaa
    33061 aaaaaatggt ataatagaat ttatggataa aaataagatt atgggattaa cccaaagaga
    33121 agtcaaggaa agacaggctg agggtttggt caatgacttt accgcatcag ccagtaccag
    33181 cacttggcaa atcgttaaac gaaatgtctt tacccttttt aacgctttga actttgccat
    33241 tgctttggcc cttgcctttg tgcaggcttg gagcaatctg gtcttctttg ctgttatctg
    33301 ctttaacgct ttttctggga ttgtgaccga gctacgagcc aaacacatgg tggacaagct
    33361 caatctcatg accaaggaaa aggtcaaaac catccgtgat ggtcaggaag ttgctcttaa
    33421 tcctgaagaa ttagtgctag gagatgtcat tcgtttgtct gcaggagagc agattcctag
    33481 tgatgccttg gttttggaag gctttgcgga agtcaatgaa gccatgttaa cgggagaaag
    33541 tgatttggtg caaaaggaag ttgacggctt acttttgtca ggaagtttcc tagccagtgg
    33601 gtcagtttta tctcaagttc accatgtcgg tgcagacaac tatgctgcca aactcatgct
    33661 tgaggctaag accgttaaac ccatcaactc ccgtatcatg aaatcgctgg acaagttggc
    33721 tggttttact gggaagatta tcattccctt tggtctggct ctcttgctgg aagccttgct
    33781 tttaaaaggc ctgcctctca agtcatccgt tgtaaactcg tcgacagctc ttttgggaat
    33841 gttgcctaag ggaattgccc ttttgaccat tacttcgctc ttgactgcag tgattaagtt
    33901 gggcttgaaa aaggtcttgg tgcaggagat gtactctgtt gagaccttgg cgcgcgtgga
    33961 tatgctctgt ctggacaaga cgggcaccat cacccaagga aagatgcagg tggaggctgt
    34021 tcttccactg acggaaactt acggtgaaga ggctattgcc agcatcttga ctagctacat
    34081 ggcccatagt gaggataaga atccaactgc ccaagccatt cgccagcgtt ttgtgggaga
    34141 tgttgcttat cctatgattt ccaatcttcc cttctcgagc gaccgcaagt ggggggctat
    34201 ggagttagaa ggcttgggga cagttttctt aggggcacct gagatgttgc tggattctga
    34261 agtcccagaa gccagggagg ccttggagag aggatcacgt gtcttggtct tagctctcag
    34321 tcaggagaaa ttagaccatc acaaaccaca gaaaccatct gatattcagg ctctagcctt
    34381 gctggaaatc ttggacccca ttcgagaggg agcagcagag acgctggact atctccgttc
    34441 tcaggaggtg ggactcaaga ttatctctgg tgacaatcca gttacggtgt ccagcattgc
    34501 ccagaaggct ggttttgcgg actatcacag ctatgtagat tgctcaaaaa tcaccgatga
    34561 ggaattgatg gccatggcgg aggagacagc tattttcgga cgtgtttccc ctcatcaaaa
    34621 gaaactcatc atccaaacgt tgaaaaaagc gggtcataca acggctatga caggggacgg
    34681 ggttaatgat atcttggccc ttcgtgaggc ggattgttct atcgtgatgg cggaggggga
    34741 tccagcaacc cgtcagattg ccaatctggt tctcttgaac tcagacttta atgatgttcc
    34801 tgagattctc ttcgagggtc gtcgcgtggt caataacatt gcccacatcg ccccgatttt
    34861 cttgataaag accatctatt ccttcctgtt agcagtcatc tgtattgcca gtgctttact
    34921 aggtcggtca gagtggattt tgattttccc cttcattccg atccagatta ccatgattga
    34981 ccagtttgtg gaaggtttcc caccattcgt tctgactttt gagcgaaata tcaaacctgt
    35041 tgagccaaat ttcctcagaa aatccatgct tcgtgcccta ccaagcgctc tcatggtcgt
    35101 cttcagcgtc ctgtttgtga aaatatttgg gagtagccaa ggttggtctg agttagaaat
    35161 ctcaactcta ctctattatc tcttggggtc aattggtttc ttatccgtat ttagagcctg
    35221 catgccattt accctatggc gtgtcctctt gattgtttgg tcagtaggag gtttcctagc
    35281 cacagctctc ttcccaagaa ttcaaaaact gcttgaaatt tcaaccttaa caggacaaac
    35341 attacctgtt tatggtgtca tgatgttggt ctttaccgtg attttcatcc tgaccagtcg
    35401 ttaccaagcg aaaaaataaa gaaagactgc aatctgtgga ttgcggtttt tttaggtaca
    35461 agattgccag ccgaaatgtg gtataataag aggtaataga gtttggaaag tgagagaaaa
    35521 tgatttcaaa gagattagaa ttggtagctt cctttgtgtc acagggggct attttactag
    35581 atgtgggaag tgaccatgct tatctgccta tcgagttggt tgagagaggc caaatcaaaa
    35641 gcgctattgc aggtgaggtg gtggaaggtc cctatcagtc tgcggttaaa aatgttgagg
    35701 ctcacggcct aaaggagaaa atccaagtcc gtttagccaa tggcttggca gcttttgaag
    35761 agactgacca agtgtctgtc attaccattg ctggcatggg tggtcgtttg attgctagga
    35821 ttttagaaga aggtttgggg aagttagcta atgtagagcg tttgatcctc cagcccaata
    35881 atcgtgaaga cgacttgcgt atctggctac aggatcatgg attccagatt gtagcagaaa
    35941 gcatcttaga agaagctgga aagttttatg agattttggt ggtggaagca ggacaaatga
    36001 agctatcagc cagtgatgtt cgctttggtc ccttcttgtc caaagaagtc agtccagtat
    36061 ttgtccaaaa atggcaaaaa gaagctgaga agctagagtt cgccctcgga caaatcccag
    36121 aaaaaaatct ggaagaacgt caagttctag tagataagat tcaagctatc aaggaggtgc
    36181 cccatgttag caagtgaagt gatccaagct tatgaagcct tttgccctca ggaattttct
    36241 atggagggag acagccgtgg tctgcaaatt ggcactttag acaagggtat ccaaagggtc
    36301 atggttgccc tcgatattcg tgaagagaca gtggcagagg ccattgaaaa gggtgtggac
    36361 ttgattatcg tcaagcacgc gcctatcttt cgtcctatca aggacttgct tgccagccgt
    36421 ccgcaaaatc agatttacat cgacctgatt aagcatgata tcgcagttta tgtcagccat
    36481 accaatattg atatcgttga aaatgggctc aatgactggt tttgtcagat gctaggaatc
    36541 gaggagacga cttatctgca ggaaacaggt ccagaacgtg gaattggacg tattgggaat
    36601 attcagcctc agacattttg ggaattggcc caacaggtca agcaagtctt tgacctagat
    36661 agccttcgaa tggtgcatta tcaagagaat gatttgcaga agcctatttc aagagtagca
    36721 atttgtggtg gaagcgggca gtctttctat aaggatgctt tggcaaaggg ggcagatgtc
    36781 tatatcactg gtgatatcta ctaccatact gctcaggata tgctgtctga tggcttgtta
    36841 gcattggatc caggtcacta tatcgaagtg ctttttgtgg aaaaaatcgc agcactcctt
    36901 actcaatgga aagagaaaaa aggctgggaa ctagagattt tacctagtca agcatcgacc
    36961 aatcctttcc gtcatatcta gttagaaagt gaagacaatg aaaaaagttg ccattattgg
    37021 agcaggaatt gtgggagcaa cagctgccta ctacctctcg agagaaagtg acctagaggt
    37081 gaccgttttt gaccatgagc aaggtcaagc caccaaggcc gcagcaggaa ttatcagtcc
    37141 ttggctttca aaacgccgca ataaggcctg gtacaagatg gcgcgattgg gggctgactt
    37201 ttatgtggat ttattagctg atttagagaa atcaggacaa gaaatcgact tttaccagcg
    37261 ttcgggagtc tttctcttga aaaaggatga atccaagttg gaagaactct atcaactggc
    37321 tctccagcgc agagaagaat ctcccttgat aggccagtta tccattctgg accaagcccc
    37381 agctaatgaa ttattccctg gcttgcaggg attcgacaac ttgctctatg cttctggtgg
    37441 agcgagagta gatggtcacc tcttagtaac tcgtttgctg gaagccagtc aggtcaagtt
    37501 ggtcaaagaa aaagtgactc tgacactctt atcatcaggc taccagattg gcgaagaggt
    37561 gtttgatcag gttattttgg caacgggagc ttggttgggg gacatgttag agcctttagg
    37621 ttatgaagtg gatgtccgtc ctcaaaaagg acaactacga gattatcagc ttgcccaaga
    37681 catggaagat taccctgttg tcatgccaga aggggagtgg gatttgattc cctttgcagg
    37741 tgggaaatta tccttgggcg ctacccatga aaatgacatg ggatttgatt tgacggtaga
    37801 tgaacccttg ctccaacaaa tggaggaggc ggccttgcct cattacccag ttttagctag
    37861 agtgacttca agggctgagc gtgtgggaat ccgtgcctat accagtgatt tctctccctt
    37921 ctttgggcag gtgccagaat tggcaggtgt ctatgcagcc agtggactag gttcatcagg
    37981 cctcacaact ggtcctatca ttggttacca tctagcccaa ctgatccaag acaaggagtt
    38041 gaccttggac cctgaaaact acccaattga aaactatgtc aaacgagtaa aaagcgaata
    38101 atactcaatg aaaatcaaag aacaaactag gaaactagcc gcggattact caaagcactg
    38161 ctttgaggtt gtggatagaa ctgacgaagt cagctcaaaa cactgttttg aggttgtgga
    38221 tagaactgac gaagtcagta accataccca tggcaaggcg acgttgacgt ggtttgaatt
    38281 ggattttcga agagtataag cattttactg aaattttatc aggtagttta ggatggcaaa
    38341 tgacattccc tgtcaaaaat ggtaaaataa gaaaaaataa tctgagaatc gaggaaaaaa
    38401 gatgcaagaa aagattttgg taactggtgg tgccggtttt attggaaccc acactgttat
    38461 tgaattgatc caagcaggcc atcaagttgt tgtggtggat aatcttgtca atagcaatcg
    38521 taagagttta gaagttgttg aaagaatcac aggagttgag attcctttct atgaggcaga
    38581 tattcgtgac acagataccc tcagagatat tttcaagcag gaagaaccga ctggtatcat
    38641 tcactttgct ggtttgaagg ctgttggcga atcaacacgt atccctcttg cctactatga
    38701 caacaatatc gctggaactg tcagcctttt gaaagccatg gaagaaaaca actgtaaaaa
    38761 catcatcttc agttcttctg cgacagttta cggggatccg cacacagtgc ccatcttgga
    38821 agatttccca ctttcagtga ccaacccata cggtcgtact aagctcatgc tagaggaaat
    38881 tttgactgat atttacaaag cagactcaga atggaatgtt gtcttgcttc gttactttaa
    38941 cccaatcgga gcccatgaga gtggtgattt gggagaaaat ccaaacggta ttccaaacaa
    39001 tctcttgcca tatgtgactc aagtagccgt tggaaaatta gagcaagtgc aagtgtttgg
    39061 agacgattac gatacggaag atggaacagg tgttcgtgat tatatccacg ttgtcgattt
    39121 ggctaagggt cacgttgcag ctttgaaaaa aatccaaaaa ggttcaggac taaacgttta
    39181 taaccttgga actggtaaag gttactcagt tcttgaaatt atccaaaaca tggaaaaagc
    39241 ggtgggacgt cctattcctt accgcatcgt agaacgtcgc ccaggtgata tcgctgcctg
    39301 ctactcagac ccagcaaaag ctaaagcaga actcggttgg gaagcagaac tcgacatcac
    39361 ccaaatgtgt gaagacgcat ggcgttggca aagcaagcat ccaaatggat ttgaagacta
    39421 agatgatgat ttcaatcatc gtcccttgtt taaacgaaga ggaagtactt cctctttttt
    39481 atcaggctct ggaagcttta cttccagatt tggaaacaga aatcgagtat gtctttgtcg
    39541 atgatggatc aagtgatggg accttggaac tcttaaaggc ctatcgggag caaaatccgg
    39601 cagtccatta tatttctttc tctcgaaatt ttggcaaaga agcagccctt tatgcaggct
    39661 tgcaatatgc gacaggagat ttggtggtgg tgatggatgc agacctccaa gatcctccta
    39721 gtatgttgtt tgagatgaaa aatgtactag acaaaaatgt agacttggac tgcgttggga
    39781 cacggagaac tagtcgggag ggagaaccct tctttcgcag tttctgtgct gttctctttt
    39841 atcgcctcat gcaaaaaatc agcccagtag ctctgccgtc gggtgtccgt gattttcgta
    39901 tgatgagaag gtctgtagtc gatgccattt taagcttgac cgagtccaat cgtttttcaa
    39961 aggggctctt cgcctgggtg ggtttcaaaa cctactattt ggactatcca aatgtcgaaa
    40021 ggcaggctgg caagacaagt tggagtttta ggcaactctt tttctactcc attgaaggga
    40081 ttattaattt ttcagatttt cccttgatta tagcctttgt agctggtctc ctatcttgtt
    40141 ttctttctct gctgatgacc ttttttgttg tggttcggac cctcattttg ggcaatccga
    40201 catctggttg gacctctctg atggctgtta ttctctttct tggaggcatt caactcttga
    40261 ccattgggat tctcggcaag tatatcagta agatttattt agagactaaa aaaagaccac
    40321 tttatcttat caaagaaaaa agtgaccttc ctgattttac agaaaaaaat aaagtgaaaa
    40381 gactataatt ttacatggaa atgtgctaaa ctagagggag tggattatcg ccattgattt
    40441 aggcttcctg gtttccaatc agggcgcgcg ttgggcaatt tttaacagcc tctaagacat
    40501 cctgactagg agaaatttct ttttccagtt ggtcagggtc atcgtaaaaa cgcacgattc
    40561 cattatcgtg gtaatcaaat aaatcagaat aagtttggca aagcccacag gcgatacatc
    40621 gttcaggtat aagtgtgatt ttcatgttca tatttatatt gtaataagaa aagtaaaaaa
    40681 aaacaaggag taaggtatgg caaaagaacc gtggcaagaa gatatctatg atcaagaaga
    40741 atcaagagca gagcgtcggc atcgaaacca cggaggggct gataggatgg ctaatcgtat
    40801 tttgacgatc ctagctagta ttttctttgt aattgtggtg gtgatggtca tcgttctcat
    40861 ctatctatca tcggggggaa gtaatcgcac agcagcctta aaagactttc atgattctga
    40921 tgcaagtgta gtacaaatct catcttcaag cagttctcag cctgagcaga gttcagagcc
    40981 agaatctact tctagtagtt cagaagaagc tgctaatcct gaaggaacga ttaaagttct
    41041 cgcaggagaa ggggaagcag ctattgccgc tcgtgcagga atctccattg ctcagttaga
    41101 ggccttgaat cctgggcaca tggctacagg atcttggttt gctaatccag gtgatgttat
    41161 aaaaataaaa taggagccga tatgaaaaca attcaaattg ctattgatgg tcctgcttcc
    41221 agcggtaaga gtacggtcgc aaagattatt gctaaggatt ttggattcac ctaccttgat
    41281 acaggagcta tgtatcgtgc agcgacctat atggctctta agaaccaatt aggagttgaa
    41341 gaagtcgaag cccttctagc cttgttggac cagcatccaa tcagctttgg acgttcagaa
    41401 actggagacc agcttgtttt tgtaggagat gtggatatta cccatcctat ccgtgaaaat
    41461 gaagtgacca atcatgtttc tgctattgca gcaattcctg aagtgcgtga gaaactggtt
    41521 tctctccaac aagaaattgc ccagcaaggc gggattgtca tggatggtcg cgatattgga
    41581 actgttgtat tgccacaagc agaattgaaa attttcctag tagcttctgt tgatgagaga
    41641 gcagagcgtc gttacaagga aaatattgcc aagggaattg aaacagacct tgaaacccta
    41701 aaaaaggaaa ttgctgcgcg tgactacaag gatagtcatc gtgagacttc tcctctcaaa
    41761 caagcagagg atgctgtcta ccttgataca actggtttga acattcaaga agtagttgaa
    41821 aaaatcaaag cagaagctga aaaaagaatg taaatgtaga aaagccgata gattgatatc
    41881 ggttttttct aaatttgtca aaatgctgat tttagggtat aatagttgct gttcgagaaa
    41941 ttttgatttt caaagaatag tgaatgatga taaggagaaa tcatgaacaa tttaccaaat
    42001 tgtccaaaat gtaactcaga gtatgtctac gaagacggtg ccctactggt ttgcccagag
    42061 tgtgctcatg agtggaatcc tgctgaagtt gcagaagtag aagaaggtct tgtcgctatc
    42121 gatgccaacg gaaataaatt ggctgatggt gatacagtaa ctctcatcaa ggacttgaaa
    42181 gtaaaaggtg cgccaaaaga tttgaaacaa gggacgcgcg tgaaaaatat ccacatcgta
    42241 gaaggcgacc acaatatcga ctgtaagatt gatggttttg gtgccatgaa acttaaatca
    42301 gagtttgtga ggaagattta agcatgtcaa aacactataa acttgtattt tatagccgta
    42361 tcttcttgtt tctagcggct tttacgggag tttatcttga aattactaag catggtggtt
    42421 ttgggatgct tctctattac acggttctgt ccaacctctt ggtaactatt tttacccttt
    42481 atcttctaaa ggttatgagc cgtgtaggtg aaaattggca aagaccaagt ctcttgcgct
    42541 taaaaggtgg ggtcaccatg agtatcatga ttacctgtgt gatttaccat ttcctcttgg
    42601 cgcccattgc gactaatttc tataccctag aaaatttcct ttgccactat atcgttccca
    42661 tctggttttt agcggatacc ctcttttttg acaaacaggg tcaatacaag atttgggatc
    42721 cagcagtgtg gaccatttta ccctttctgt atatgatgtt tgctcttttt aatggcttgg
    42781 ttctaaaact caatattcca aatgccaagg ataatccttt cccttacttc tttttgaatg
    42841 tgaacaaggg ttggaatgtt gtgtttaagt ggtgtctgat tatctttgtt gcctatatgg
    42901 tagcaggatt tattttctac tttatcaagc aaatcaagag aaagtcatcc taatactctt
    42961 cgaaaatctc ttcaaaccac gtcagtttcc atctgcaacc tcaaaacact gttttgaaca
    43021 acctgcggct agcttcctag tttgctcttt gattttcatt gagtataaga tacaagggat
    43081 tcattttcga atttaagaag gagtctacaa accaatgagg cttcttcttt tcttgcttat
    43141 ttgataacta tcaaaaaagt agaagattaa gagaaatata gaaagagatt tcatgaaaca
    43201 atttttagaa cgggccagca ttttggctct ctccctcgtt ttgattacct ccttttccat
    43261 ttcgagtgcc ctaccagcca tgtttgacta ttatcagggt tattctaagg aacaaattga
    43321 gctcttggtg agcttgcctt cctttggaat catgatgatg ttactgctaa atggtttctt
    43381 agaaaaaata tttcctgagc gcttacagat tagtttgggc ttgctgattt tatcattgag
    43441 cggtacagct cccttctggt accaagccta tccctttgtc tttggagcac ggcttctctt
    43501 tggtttgggt cttgggatga tcaatgccaa ggccatttct attatcagtg aacgctacca
    43561 aggaaaaagg cgaattcaga tgttagggct acgcgcttct gcagaggtcg ttggagcttc
    43621 tctcattacc ttggccgtcg gtcagttgtt ggcctttggt tggacagcta tctttctagc
    43681 ctatagtgct ggatttttgg tgctgcccct ttatctgctc tttgtccctt atggaaaatc
    43741 aaagaaagaa gtcaagaaaa gagcgaagga agcaagtcgt ttaactcgag aaatgaaagg
    43801 cttgattttt accttagcta tcgaagcggc agttgtagtt tgtaccaata cagctattac
    43861 catccgtatt ccaagtttga tggtggaaag aggattgggg gatgcccagt tatctagttt
    43921 tgttcttagt atcatgcagt tgatcgggat tgtggctggg gtgagttttt ctttcttgat
    43981 ttctatcttt aaagagaaac tgctcctctg gtctggtatt acctttggct tggggcaaat
    44041 tgtgattgcc ttgtcttcat ccttgtgggt ggtagtagca ggaagtgttc tggctggatt
    44101 tgcctatagt gtagtcttga cgacggtctt tcaacttgtc tctgaacgaa ttccagctaa
    44161 actcctcaat caagcaactt catttgctgt attaggctgt agtttcggag cctttacgac
    44221 cccatttgtt ctaggtgcaa ttggcttact aactcacaat gggatgttgg tctttagtat
    44281 cttaggaggt tggttgattg taatctctat ctttgtcatg tacctacttc agaagagagc
    44341 ttaggattga ttcctaagtt tttcttttga tactcaatga aaatcaaaga gcaaactata
    44401 gttgattgag tttggaatag tacgctgtag ctgctaaaat atttctagaa attaatttga
    44461 ctttcctaat agagttattc atatcttatt tcaatctact atagaaagct agccgcaggt
    44521 tgctcaaaat agtgttttga ggttgcagat ggaaactgac gtggtttgaa gagattttcg
    44581 aagagtatga gatttttata cccatacaat atttgtttta ggtccttgtt tacagactaa
    44641 tttcttgata aaatagaggt tatgacgaga tataaagcaa ctatttccta tgatggttat
    44701 gcctttgctg gctttcagcg ccagtctcat gcgcgtagcg ttcaggaaga aattgaaaaa
    44761 accttgacca gattaaataa agggcaagcc attactgttc acggtgctgg taggacagat
    44821 agtggggttc atgccctggg acaggtcatt cattttgacc tgccttatca gattgatgag
    44881 gagaaactcc gttttgcctt ggatacccag tctcctgaag atattgatgt gatttcgatt
    44941 gagcttgtgg cagatgattt tcattgccgt tatgccaagc atagcaagac ctatgagttt
    45001 attgtggata gaggacgtcc caaaaatccg atgcgccgtc actatgccac ccactttccc
    45061 tacccactcg atgtggaacg aatgcagatt gcaatcaaaa agctagaggg aacccatgat
    45121 tttaccggtt ttacagcctc tgggactagt gtagaggata aggttcgcac catcacagaa
    45181 gctagtttaa tagtcgatga gacaggacaa tttttgacct ttaccttttc cggaaatggt
    45241 ttcttgtata aacagattcg caatatggtg gggactcttc tcaaaatcgg taacaaccgc
    45301 atgccagtag agcagattga tctcatcttg gagaagaagg acaggcaact tgcaggtccc
    45361 actgcagcac caaatggttt gtatttaaag gagattcgtt atgaagaata atcgtatttt
    45421 agcactttct ggaaatgata tttttagtgg tggtggactg tcagctgatt tggctaccta
    45481 taccttgaac ggcttgcatg ggtttgtagc agtgacttgt ttgacagcct tgacagaaaa
    45541 aggatttgaa gtctttccaa ctgatgatac catttttcaa catgaattag atagcttgcg
    45601 tgatgtggaa tttgggggaa ttaagattgg tcttctccct actgtcagtg tggctgagaa
    45661 ggccttggac tttatcaaac aacgcccagg agtacctgtg gtgttggatc ctgtcttggt
    45721 ctgcaaggaa acgcatgatg tagctgtcag tgagctctgc caagagttga ttcgcttttt
    45781 cccttatgtc agtgtgatta cgcctaatct cccagaagca gaattattat ccggtcagga
    45841 aattaaaacc ttggaagaca tgaaaactgc agcgcagaaa ttgcatgatt taggagcgcc
    45901 agcagtcatt atcaagggag gcaatcgtct tagtcaggac aaggctgtgg atgtctttta
    45961 tgatggacag acctttacta tcctagaaaa tccagttatc caaggccaaa atgctggtgc
    46021 aggttgtacc tttgcctcta gcattgccag tcacttgatt aaaggtgata aacttttgcc
    46081 agcagtagaa agctctaagg ctttcgttta tcgtgctatt gcacaagcag atcagtatgg
    46141 agtaagacaa tatgaagcaa acaaaaacaa ctaaaatcgc ccttgtatcc ctattaaccg
    46201 ccctttctgt ggttctaggt tatttcttaa aaatcccaac acctacagga attctaactc
    46261 ttttagatgc tggtgtcttc tttgcggcct tttactttgg tagtcgtgaa ggagcggtag
    46321 tcggaggact agcaagtttc ttgattgacc tcttatcagg ctaccctcag tggatgttct
    46381 ttagcttggt caaccatggc ttgcagggat ttttcgcagg atttaaagga aaaagtcagt
    46441 ggttaggcct tattttagca actattgcca tggtaggagg ctacgccttg ggttctactt
    46501 tgatgaatgg ctgggcagca gccctcccag aaattctacc aaatttcatg caaaatatgg
    46561 tagggatgat tgtaggattt attcttagtc aaagtatcaa gaagattaag taatactctt
    46621 cgaaaatctc ttcaaaccac gtcagtttcc atctgcaacc tcaaaacact gttttgagca
    46681 gcctgcggct agctttctag tctgattttc attgagcata aagaggttga gtaaaaagtc
    46741 tttcaaataa gaaaaacgca tagtatcagg tgttgaatga acacctgata ctatgcgttt
    46801 tattgtggga agattttcct cattttctag tgaaattgaa ctttttctaa catcttttga
    46861 tagatgactt cttaatcaat tatcatttcc attgttgttt cttggggttt catcccttgt
    46921 ctttgataaa agcggagagc accctcgtta tcattccaga cacttagggt tagattattg
    46981 cagccaattt ctttagcata atagcagaaa aatgacaata aaatagcccc tagatatttt
    47041 gaaaggaaag cataggggct atatagttta atcaaaataa agcaaatctt tgctggtgct
    47101 tgtaaagagg tcgaagccat ccttggtaac aacaccgcag tcttcaatac gaacaccgac
    47161 tttaccaggg atatagatac ctggttcaac agagaagcac atgccttctt cgatgaccat
    47221 gtcgtttcct tccatgatag atgggaattc atggacatcc ataccgatac catgcccgag
    47281 acggtggttg aagtactcac cataaccagc tttttcgatg acctcacggg cagcgcggtc
    47341 cacttcatga gcagtcacac ctggcttgat aaagtcaaga gcagcttgtt gggcttcaag
    47401 agtcaagttg taaatatctt tcttgaattg gtctggtttg ccgacagcga ctgtacgagt
    47461 catatctgac gcatagccat tgaccagaac acccaggtca aagaggagaa gagcatcatt
    47521 ttcaacctta ttagctgctg gaatgccgtg tggattcgca gcattatcac cagtcaagac
    47581 catggtatca aagctcattt cgtaaccttc acgtttcatg gcaaagtcaa tttgtgcgat
    47641 gatatctgtc tcagtcttat caagagaaat attgtcaaaa ccaacatgaa cagccttgtc
    47701 agcataaaga cctgcaacca tcattttttg cacttcatca gctgatttga tgaggcgcat
    47761 gcgttggata cgaggagtga ggttgtcaaa ctcagcagtc tcaaaaactg ttttcaaacc
    47821 atggtatttg gtcaagatga gattgtcaaa ctcaacagcg acacgtttga agtcaagttg
    47881 tggaagagca tgtttgattt tttgccatgg attttcagaa tcgacatagc ccactactgg
    47941 gaaggaaacg gtgctacttg cacgttctac ttcaagagct gggacaaaga ggagaggttc
    48001 ctgatctgct aggacaaaga ggaacatttg gcgttcatgg ggatcactgt aaaaaccagt
    48061 gaggtaattg attgtgacgg ggtcagatac gacagcgacg tctagttttt ctgattcaag
    48121 atatgttagg atttgttgta atttagacat atgctacctt ctttctatcc ctctattttg
    48181 gcaaaaaatg agagaaaatg caagggagaa gggtaaaaga aaagacaaaa aactccgaca
    48241 agataacgga gttctttgat atcattttcc tttgtttaag aaaagtcagc cttgcttttg
    48301 acgtcactgt actcttcagc gatttcttgg ctgaggatat cctcataggc agggagttgg
    48361 atgtcctgac catatttctt cttgagggca gtagtaacta ggcgataagc cagattggca
    48421 ttacgagaga ggataggccc gtggaagtag gaaccaaaga cattcttata atgaacccct
    48481 tcaccgacct tttcttcgtt gtttccattt ccatagacaa cctgtcccag cggtttttgg
    48541 tcatcagaga ggaaggtacg gccttggtga ttttcaaatc catagtaggt ttcatcgaaa
    48601 tcttcattgt gaatcttgat gtcaccgata aaacggttat tggtctggtt gagcgtgtag
    48661 tgtcccatga cccctagccc ttcgatacgt tttcctgaag cttcaacata atattgaccc
    48721 aatagttgga aaccaccgca gatagccaga actacaccgt cgttttggat gtagttgtca
    48781 atgctctctt ttttagcagg taggtcgtct gcaatgatac tttgttcaaa gtcttgacca
    48841 ccaccgaaaa aggcgatgtc gtagtgattt tcatcaaagt catcatggag agaaacgatg
    48901 tcaacggtca catgggctcc cagtttttca gccacatact tgagcatgag gatgtttcca
    48961 ttgtccccgt aggtattcat gagatttccg tagaggtggg caatgttgag ctgatagggg
    49021 taattgccat cttttgagga aagtgaagta taaaccatta gttcatctcc tttctaacaa
    49081 tctgacgact agccagcagt tcacgaaatt ccagcatggc agtataagtt gccagaatat
    49141 aggcatgctt gcagtcttga ttctcaatgg tcttgagaac ttgctccaga ttactcgttt
    49201 cagtgatttt ctcagctgga tagccagtca ctcggaggcg acgagcgatt tcagaatgac
    49261 gaacaccgcc agcgttgatt tcaggaatgt ccatgtcagt gatttgttca aagtctgcat
    49321 cccagatcca gctagtgtca attccatctg catagttggc attaaggagg acagataggc
    49381 taaatggata aggtgctagt ttgatcattt cgatagcttg ggttgcaccg actggatttt
    49441 taatcaagac aagggtacat tccttgtcac cgatatgaaa ggtttcttgg cgtccaaaga
    49501 cagcacggct cttgtcaaat ccctgtttga tgagttgcga atcggcacct aggaaacggg
    49561 cgatggccac agcagctagg gcgttataga tattatagag cccgccgatt tggataccgt
    49621 attcttggac gtctatgaca aagcgagagc gattgttggt caactcaacc agttttgtca
    49681 aacgatagtc gagatcagga cgtttacatc cacaaccttc acagatatag gtacccaagt
    49741 ttgcataggt attatgctca tatttgagga tgccttggca gtcaggacag agaatccctt
    49801 cggtattgta gtgagccagt tgggctggtc ctttttccaa gtcaaaacca aaatactcta
    49861 tagggtttgg aatagttggc ttgtagaaaa gtggactgtc tccgttaagg agaacagtag
    49921 cagttggaac tttccgaatg gcatccaata tcatgttata ggtagtatag atttcaccga
    49981 aacggtccat ctggtcacgg aagatattag taatgacaaa aagactaggc tggatatagt
    50041 cacagatacg agatagactg gcttcgtcaa tttcgaggac ggcaatattt tttccagttt
    50101 tagaagattt ggctgttagg aaggttgttg caatccctgt aatcatgttg gcaccgcttg
    50161 gattggttag aacttgacca tagacctctt ttaaaatgcc gacagtgagg gcagttgtca
    50221 gggtttttcc atttgttcca gtgacaacga caatctcgta gttcttagct aggttttgta
    50281 aaatatcttt atcaaattga agggcgactt tacctgggag cgtacttcca cggccaagac
    50341 ggcttaaaat gaagtgggaa gaacgcccag caagaaggcc caaagtagtt tttaagttca
    50401 tgtttctatt atatcataaa agaggagaaa gacagatttg agattccgca gaagtaaaaa
    50461 cagcccaaag agggctgttc gatacgatta aatctcaact taaatcgcaa acaagtcatt
    50521 caagttctca gccaaggttg ggtgagtgaa gatttgtttt gtgaagtaag tgtaaggaat
    50581 cttgttgtcc atagcaacag tgatgatgtt gatgatttct tgagaacctt ctgagaagat
    50641 gcttgctcca agaatttctt ttgtttcagt attgacaaca gctttgaagg caccgcgaag
    50701 gtctccattt acgtgaccac gaggcatggc tgcaacgggg atttccttaa cagcgtatgg
    50761 aagtttcaaa tcagctgctt ggctttcagt caaaccaact tgtgaaagtg caggtgtgat
    50821 gaacatagta tttggcacat tgagacggtc ttcaagtgtg tagctgccat ctccagcaag
    50881 gtagctgtaa acaacacgga agtcatcaag tgaaatgtaa gtaaattgaa ggccaccgtt
    50941 gatatctcca actgcaaaga caccaggaac gtttgtttga cagtgtttgt ctactttaat
    51001 agcaccacgt tcagttagtt caatatctgt attttcaagt tgaagtggtt ctacatttgg
    51061 tttgcgtcca gttgcgtaga gaagggcgtc gaaacggtaa gtttcgtctt cagttacgac
    51121 aagcacttgg tcaccatcgt ttttgatttc agtagtatgg atattttgaa gcaattcaat
    51181 gccatcttct tccatgtatt gtttagcaag agctgcgatg gaaggttctg cacgaggaag
    51241 gaaagtatcc aaggcatcta ggactgtgac cttgcttcca agtttgttgt aaaggccggc
    51301 aaattcaaga ccgatatttc cgccaccaag gattccaagt ttttcaggta atttgtccaa
    51361 gttttggata cctgttgagt caaagatgtt tttgcttgta gcaagtccag ggattggcaa
    51421 gacgtttgaa acagcaccag tgttgatgac gattgtttca gcagtcagtt ctttcttttc
    51481 atcaccagct tggatttcga tgactttatt tgaaaggaag tgagcttccg catcaaagat
    51541 atctacgcct gtaccagcaa cagtcgcata gtttttaccg ttgaggcgac cagtgatcgt
    51601 gtttttagta gcaatcactt cttcaaaaga caagtccttt tcagcagcaa ctagcaaggt
    51661 tttagttggg atacaaccaa tgttgataca agttccaccg tacatagcct tgctgcgttc
    51721 aacgagggca acttttttgc cagctgaagc caatttacct gctagtgttt taccagcttt
    51781 accaaatcca ataacaatta aatcgtatgt taacatttat cttcctccta ttcgaatttc
    51841 attctagcac aagaaaaaaa cttttgcaca attctgctac ggaaaagaca gaaaaagata
    51901 aaaacgcttt ccagacaaaa aactagtaat tttttgacaa gcttgataaa ctaaaatcct
    51961 atctattttt atataagata gaataaatgt tcgaaaatag gaggttttat gaaatcgaat
    52021 cgttatatta ttgcctttgc tggggtcatt ttacacttaa tgctgggttc gacttatgct
    52081 tggagtgttt atcgtaaccc tattattgaa aaaacgggat gggatcaggc ttctgttgcc
    52141 tttgccttta gtctagcaat cttttgtttg ggcttatcgg ctgcatttat ggggcgtttg
    52201 gtagaaaaat ttggtccgag agtcatgggg agtctatctg cttttctata cgcaggtgga
    52261 aatatcttaa caggatttgc aatagaccgt caggagctgt ggttgttgta tctcgcttat
    52321 ggcattttag gtgggcttgg tttgggagca ggctatatta cccctgtgtc gacgattata
    52381 aaatggtttc ctgataaacg tggtctcgca acaggtttag cgattatggg gtttggtttt
    52441 gcttctttat tgactagtcc catagcgcaa cacctcatcg caggggtagg gcttgtagaa
    52501 actttttata ttttaggagc aagttacttt attatcatgc tcctagcttc acaattcatt
    52561 aagcgtccaa atgagcaaga gcttgcaatt ttatcttctt cagggaaaga aaaaacagcc
    52621 tctttgacgc aaggaatggc tgcaaatcag gctctaaaaa gcaatcggtt ttatatactt
    52681 tggattattt tctttatcaa catagcttgt ggtttaggct taatttcagc ggcatcgcca
    52741 atggcacagg agatggctgg cttgtctaca agtcatgcag cagtaatggt gggcgtttta
    52801 gggattttca atggatttgg tcgcttgctc tgggcgagct tatctgacta tatcggtcgc
    52861 cctctaacct ttagtatatt actgcttgtt aatcttttct tttctctctc actttggctc
    52921 tttacagatt ccgttttatt tgtagtcgct atgtctattt tgatgacttg ctatggagct
    52981 ggtttttcat tgatcccagc ttatctcagt gatatttttg gaaccaagga attggccgct
    53041 ctgcatggat atattttaac agcttgggca atggctggtt tagcgggacc tattttatta
    53101 gcagagactt ataaaatggc tcattcgtac acacaaacct tgttcgtttt tctcatttta
    53161 tacagtatcg ccttggcttt gtcttattat ctaggtcgtt caatcaaaaa agaaagtcaa
    53221 aaaccgctta catgattttc tgtagaaatg gggctatctt ttgctctggt cttgtgttat
    53281 actagatagg ttgcaaagaa aacagtactt ttcttttgtg gaaaagaagc aacacgattt
    53341 tatatctagt tatatgaaaa tacgtcataa aaagaaaagt ataaactaag ccctataggg
    53401 tggcttcgca ccacctttag aaagaagaat aacgtgaaat ttaatgaatt aaacttgtct
    53461 gctgatttgc tggcagaaat tgaaaaagct ggttttgtag aagctagtcc tatccaagaa
    53521 caaactattc ctttggccct tgaaggcaag gatgttatcg gtcaagctca gactggtaca
    53581 ggaaaaactg cagcctttgg cttgcctacc cttgaaaaaa tccgtacaga agaagcgact
    53641 atccaagcct tggtcatcgc tccaactcgt gaactagctg tccaaagtca agaagaactc
    53701 ttccgctttg gtcgtagtaa gggagtcaaa gtccgttcag tatatggcgg atcaagcatt
    53761 gaaaaacaaa ttaaggctct taaatctggt gcccatatcg tggtgggaac tccaggtcgc
    53821 ctcttggact tgattaaacg caaggccttg aaattacaaa acattgaaac ccttatcctt
    53881 gacgaagcgg atgaaatgct taacatgggc ttccttgaag acatcgaagc cattatttcc
    53941 cgtgtacctg agaaccgtca aactttgctt ttctcagcaa ctatgccaga tgccatcaaa
    54001 cgtatcggtg ttcagtttat gaaagcccct gaacatgtca agattgcagc taaggaattg
    54061 acaacagaat tggttgacca gtactatatc cgtgttaagg aacaagaaaa atttgacacc
    54121 atgactcgtc tcatggatgt ggcacaacca gaactcgcta ttgtatttgg tcgtaccaaa
    54181 cgccgtgtgg atgaattgac tcgtggtttg aaaattcgtg gcttccgtgc agaaggaatt
    54241 catggcgacc tagaccaaaa caaacgtctt cgtgtccttc gtgactttaa aaatggcaat
    54301 cttgatgttt tggttgcgac agacgttgca gcgcgtggtt tggatatttc aggtgtgacc
    54361 catgtctaca actacgatat tccacaagat cctgagagtt atgttcaccg tatcggtcgt
    54421 acaggtcgtg ctggtaagtc aggtcaatct attacttttg ttgctccaaa cgaaatgggt
    54481 taccttcaaa tcattgaaaa cttgactaag aaacgcatga aaggtctcaa acctgcaagt
    54541 gtagaagaat ccttccaatc aaaaaaacag gtagctctca agaaaatcga acgtgatttt
    54601 gcagatgaaa ccattcgtgc caactttgag aaatttggta aggatgctcg caaattggct
    54661 gctgagttta ctccagaaga attggcaatg tatatcttga gtctgacagt ccaagaccca
    54721 gatagccttc cagaagtgga gattgcacgt gaaaaaccac taccgtttaa accatcaggt
    54781 aatggtttcg gtggtaaagc taagggaggt cgtggaggcc gtcgtgggga cgaccgtcga
    54841 gagcgtgatc gccgtggcaa tggtcgccgt gatgagttca aaaaaggaag tcgtggcaac
    54901 gatcgttttg ataaggaaaa acgttaccgt aaggataata aaaaaccacg caatacttta
    54961 agcgaaaagc aaacaggctt tgttattcgt aacaaaggcg ataaataaga aaaagcggtt
    55021 caaaatgaat cgctttttta tataaggaga ccgaatgtga aaagacaaat aaaattatta
    55081 tattatcttt tataatgtta tgatacacaa aaataggcaa cttgtcaata gaaaaggaac
    55141 aatttaatta aaaatattct ggtttttaat taaattgtaa gtcaatgcaa gtcaataagg
    55201 aattttcaga taattattga aaaagagacg tttttatgtt ataatgatag cgattaaatt
    55261 cgaggtgaaa aatggcacat ttattagaaa aaactagaaa aattacatca attttgaaac
    55321 gctcagagga gcagttgcag gatgagctcc cttacaacgc tattacgcgt cagttagcgg
    55381 atattattca ttgcaatgcc tgcattatca atagtaaggg acgtctgctt ggctatttta
    55441 tgcgttataa aacaaataca gatcgcgtag agcaattctt ccaaactaag attttcccag
    55501 atgactacgt tcaaggggct aatatgattt acgaaacaga agcaaacttg cctgttgagc
    55561 atgatatgag tattttccct gttgagagta gagatgattt tccagatggc ttgacgacta
    55621 ttgcaccgat tcatgtatcg gggattcgcc ttggttcttt gattatttgg cgtaatgata
    55681 aaaaattcga agatgaggac ttggttcttg ttgagattgc cagtaccgtt gttgggattc
    55741 agcttcttaa cttccaacgt gaagaagatg agaaaaatat tcgtcgtcgt actgctgtca
    55801 ccatggcggt caataccctt tcttactccg aactccgtgc tgtttcagca attttagggg
    55861 aattaaatgg aaatgaaggg cagttgactg cgtcagtgat tgcagatcgt atcggaatca
    55921 ctcgctctgt gattgtcaat gctcttcgta aacttgagtc tgcggggatt attgaaagtc
    55981 gctcacttgg aatgaaggga acctatctta aggtcttgat ttcagatatt tttgaagaag
    56041 tgaagaaaag agattactaa tgacaaaggc tttaatttcg attgattata cagaagattt
    56101 tgttgctgat agtgggaagc tgacagcagg tgctccagct caggcgattt cggatgccat
    56161 tagcaaggta actcgattag cttttgaacg aggagattat atcttcttta ctattgatgc
    56221 tcatgaagaa aacgattttt tccatccgga aagtaagtta tttcctcctc ataatctgat
    56281 tgggacgagt ggacggaatt tatatggaga tttggggatc ttttatcaag agcatggttc
    56341 agacagtcgt gtcttttgga tggataaacg ccattactca gctttttcag ggactgacct
    56401 agatattcgt ttgagagagc gtagagtgtc taccgttatc ttaacaggtg tcttgacgga
    56461 tatctgtgtc ctacatacag ctatagatgc ctataatcta ggatatgaca tcgagattgt
    56521 taaaccagct gttgcttcca tctggcctga aaatcatcaa tttgccctag gtcatttcaa
    56581 aaatacactc ggagctaagt tagtagatga aaatctaaat gaactttctg agtaacctgg
    56641 ttggtgaaaa tgaaaaaatt tgaaaaaaag tgttgacaag catcccaaaa gttgatatac
    56701 tagtaaagta atcgatgcgg ggatggcgga attggcagac gcgcaggact aaggatcctg
    56761 tgaccgcttt aggtcgtgag ggttcaagtc cctctctccg cataggaaaa gagttagcta
    56821 aagctagctc ttttgtattt ctctaaaaaa ttagaatcca gtcaaatgta gtggagaatc
    56881 agcgaaaata tgggaaaact gatccttgtt tctgcttttg tcatagaaga ataataaaga
    56941 ttatcttctt caaattctcc gatattctct aaagttttgt gcaagttgca cagaactttt
    57001 ttattttttt ggtcatcttg ccatagaaat ataaagcgtt ttcatatata atataattat
    57061 caaaagacaa aaggagttca cctcatggta gaattgaatc ttaaaaatat ttacaaaaaa
    57121 tatccaaaca gcgaacacta ttcagttgaa gatttcaact tgaacataaa agataaagaa
    57181 tttatcgttt tcgtaggacc ttcaggatgt ggtaaatcaa ctacactccg tatgattgct
    57241 ggtcttgaag acattacaga aggtactgca tctatcgatg gcgtggttgt caacgacgta
    57301 gctccaaaag accgtgatat cgccatggta ttccaaaact acgctcttta cccacacatg
    57361 actgtttatg acaacatggc tttcggcttg aaattgcgta aatacagcaa agaagacatt
    57421 aacaaacgtg ttcaagaagc agctgaaata cttggattga aagaattctt ggaacgtaaa
    57481 ccagctgacc tttcaggtgg tcaacgtcaa cgtgttgcca tggggcgtgc gattgtccgt
    57541 gatgcgaaag tattcttgat ggacgaacct ttgtcaaact tggatgccaa acttcgtgta
    57601 tcaatgcgtg ctgaaatcgc taaaattcac cgtcgtatcg gagctacaac tatctatgta
    57661 actcacgacc aaacagaagc gatgacactt gcagaccgta tcgttattat gtcagctact
    57721 aagaaccctg ctggtacagg tactatcgga cgtgtagaac aaatcggtac tcctcaagaa
    57781 gtttacaaaa atccagttaa caaattcgtt gcaggattca tcggaagccc agctatgaac
    57841 ttcatcaccg tgaaattggt tggtagcgaa attgtttctg acggtttccg tttgaaagtg
    57901 ccagaaggag cattgaaagt tcttcgtgaa aaaggctacg aaggaaaaga attgatcttt
    57961 ggtatccgtc cagaagacgt gaatgcagaa cctgctttcc ttgaaacatt cccagactgt
    58021 gttgtaaaag cgactatctc tgtatcagaa ctgcttggtt cagaatctca cctttactgc
    58081 caagttggta aagacgagtt tgttgcaaaa gttgatgctc gtgactactt gcaaacaggt
    58141 gcaacagttg agcttggatt tgacttgaac aaagcacact tcttcgatgt agaaactgaa
    58201 aaaacaatct actaaaataa ataaaattca aagcactaca agaaaagata tctctttatc
    58261 aattgtagtg gagagatatc agttaatcta gggagagaaa caaaatgctt ctctcctttt
    58321 tgctagggaa gtcatattat gcatctatat tgtgatgctc tttatactct tcgaaaatct
    58381 cttcaaacca cgtcaacgtc gccttgccgt acgtatgatt actgatttcg tcagttttat
    58441 ctgcaacctc aaagatgtac tttgagcagc ttacggctag tttcctagtt tgctctttga
    58501 tttccattga gtattattgt gagtaccatc tacaagtgaa gctatatgcg taaactacgt
    58561 gagcaattga attcgaacta gagaggtaat aataaattta tgctatagtt atggtgactt
    58621 gtatgctttt gattctagtt tatcaaataa tagattagaa ttgtcagata atatcatttt
    58681 gtgttataat gaagaaaaaa cagaggtgtt caaatgtcag aagcaggtca taagttttta
    58741 gcaaaattgg ggaaaaaacg cttacgtcca ggtggaaagc gtgccacaga ttggttaatt
    58801 gcagaaggag gattttcaaa agaaaagaga atactagagg ttgcgtgtaa taggggaact
    58861 acagcaattg agttggcaca gcgttttggt tgcaagataa ctgctgttga tatggatgct
    58921 caagctttag aagtggctaa aaaatctgct ggaacggcag gtgttgctca tttaatcagt
    58981 tttgaaagag caaatgcaat gaaacttcct tatcaagatg ctagttttga tattgttata
    59041 aatgaagcta tgctgactat gcaagccgat caagctaaga aaaaatgtgt aatggaatat
    59101 ctaagggtat taaaacctgg aggtcttctc ttgacacatg atgtgcttct taaggaagct
    59161 aaagagtcta tcagacagga attatcacaa gcaattcatg taaatgtagg tcctttaact
    59221 caagatggtt gggaacaggt gatgatagaa tcaggttatt gtgatgtgaa agcattgact
    59281 ggtgaaatga cattaatgaa attatcgggt atgatttatg acgaaggttt gctaggaact
    59341 ttgaaaattt gtgtaaatgc ttgtaaaaag gagaatagaa agcagttttt aactatgtat
    59401 aaaatgtttg ctaagaataa acagaaattg ggctttattg cgatggctag ttataaatcg
    59461 tcaaaacgtt agataattat tgaagttaac ttttcctttt ttctttctta aaaaatatgc
    59521 tataatagag agtaaaaaac tttgaaagaa agaaaaaaga tgaatttaaa agattacatt
    59581 gcaacaattg aaaattatcc aaaggaaggc attaccttcc gtgatattag tcctttgatg
    59641 gctgatggaa atgcttatag ctacgctgtt cgtgaaatcg ttcagtatgc tactgacaag
    59701 aaagtcgaca tgatcgtggg acctgaagct cgtggattta tcgtgggttg tccagttgcc
    59761 tttgagttgg gaattggttt tgcgcctgtt cgtaagccag gtaaattgcc acgtgaagtt
    59821 atttctgctg actatgaaaa agagtacggt gtcgatacct tgactatgca cgcggatgcc
    59881 attaagccag gtcaacgtgt tcttattgta gatgaccttt tggcgacagg tggaactgtt
    59941 aaggcaacta tcgagatgat tgaaaaactt ggtggtgtta tggcaggttg tgccttcctt
    60001 gttgaattgg atgaattgaa cggccgtgaa aaaattggtg actacgacta caaagttctt
    60061 atgcattatt aatgaaaaca gtccctaggg ctgttttctc tacactagga tataaaaata
    60121 gactataact agttagagaa aaactataat tgaaaactat atcttcttgc agtataataa
    60181 aaggactaag tgtttgagat ttgtcttcaa acatatgcaa ttattcctga aagagtacag
    60241 ttaggagagg gttatgccga ttcgaattga taaaaaattg ccagctgttg agattttacg
    60301 gacagagaat atctttgtca tggatgatca acgtgctgcc caccaagata tccgtccttt
    60361 gaagatttta attttaaatc tcatgccaca gaaaatggtc acagagaccc agttgttgcg
    60421 ccacttggct aatacacccc tacaactgga tattgatttt ctctatatgg agagccaccg
    60481 ttctaaaaca actcgttcag agcacatgga gaccttctat aaaacttttc ctgaagtcaa
    60541 ggatgagtat tttgatggga tgatcatcac gggtgctcca gttgagcatt taccatttga
    60601 ggaagtggac tattgggagg aatttagaca gatgcttgag tggtctaaga ctcatgtcta
    60661 ttcgaccctt catatctgtt ggggggctca ggctgggctt tatctgcgct atggtgtaga
    60721 aaaataccag atggacagta agctatcagg tatttatcct caggacaccc taaaagaggg
    60781 tcaccttcta tttagaggct ttgatgatag ctatgtatcc cctcattcac ggcacacgga
    60841 gatttctaag gaagaggtct taaacaagac caatctcgag attttatcag aaggacctca
    60901 ggttggggtt tctattttgg ccagtcgtga tttacgagaa atttatagtt ttggtcattt
    60961 ggagtatgac cgtgatacct tggcaaaaga gtattttcga gatcgtgatg caggtttcga
    61021 cccacatatt ccagaaaatt actttaaaga tgatgatgtt aatcaggtac cttgtctttg
    61081 ttggtcttca tctgcagccc tctttttcag taattgggta aaccatgcgg tctatcagga
    61141 gacgcctttt gattggagaa agatagaaga tgatgcatct gcatatgggt atttataaga
    61201 ggaattatga catatttaga cgcttttaaa tcaggtacct tggttttacc gagtgccctg
    61261 ctcttgcatt ttaaggaact ctttccttct agcgacgatt ttctggtttg gcaatttttc
    61321 tatttgcaaa atacgacagg cttagaagaa atgtcgccaa gccagattgc tgaaaggatt
    61381 ggcaaggaaa tttcggatgt caaccagtcc atttctaatc tgacggaaag gggactgctc
    61441 cagtatcgta ctatcgaatt aaatggcgaa attgaattgc tctttgatgc tagtttggcc
    61501 ttggaacgtt tggatgacct gtttggagca gttcattcaa gttcagacca gctaacacct
    61561 caaaaccagc tcaaggattt ggtggaaacc ttccagcagg agttgggacg attgttgacg
    61621 ccttttgaga ttgaggattt gaccaagaca ctaaaggaag atggaaccag tgctgacttg
    61681 attaaggagg ctcttcgtga agctgttttg aatggaaaac caaactggaa gtacattcag
    61741 gctattttga gaaactggcg ccatgaagga atcaagagtg tggctcaaat tgaggccaag
    61801 agagcagaaa gagaagcaag caatcctcag ttgacacagg tatctgcaga tttcagaaat
    61861 gccatggatc tctggaagga ttaatccatg caagtaggct tgaaatccga gtaagatttg
    61921 caagctgtgt ataattgtga tagaataaat agaaaataaa ttgaaaaaag aggtatgtga
    61981 aatgtcacgt aaaccattta tcgctggtaa ctggaaaatg aacaaaaatc cagaagaagc
    62041 taaagcattc gttgaagcag ttgcatcaaa acttccttca tcagatcttg ttgaagcagg
    62101 tatcgctgct ccagctcttg atttgacaac tgttcttgct gttgcaaaag gctcaaacct
    62161 taaagttgct gctcaaaact gctactttga aaatgcaggt gctttcactg gtgaaactag
    62221 cccacaagtt ttgaaagaaa tcggtactga ctacgttgtt atcggtcact cagaacgccg
    62281 tgactacttc catgaaactg acgaagatat caacaaaaaa gcaaaagcaa tctttgcgaa
    62341 cggtatgctt ccaatcatct gttgtggtga atcacttgaa acttacgaag ctggtaaagc
    62401 tgctgaattc gtaggtgctc aagtatctgc tgcattggct ggattgactg ctgaacaagt
    62461 tgctgcctca gttatcgctt atgagccaat ctgggctatc ggtactggta aatcagcttc
    62521 acaagacgat gcacaaaaaa tgtgtaaagt tgttcgtgac gttgtagctg ctgactttgg
    62581 tcaagaagtc gcagacaaag ttcgtgttca atacggtggt tctgttaaac ctgaaaatgt
    62641 tgcttcatac atggcttgcc cagacgttga cggtgccctt gtaggtggtg cgtcacttga
    62701 agctgaaagc ttcttggctt tgcttgactt tgtaaaataa tcagtaagta gcaaaagcta
    62761 ggtggaacag cattcagatg tctgttacat tttttatagg agagcaaaga ttgaaaacaa
    62821 aaattggatt agcaagtatc tgtttactag gcttggcaac tagtcatgtc gctgcaaatg
    62881 aaactgaagt agcaaaaact tcgcaggata caacgacagc ttcaagtagt tcagagcaaa
    62941 atcagtcttc taataaaacg caaacgagcg cagaagtaca gactaatgct gctgcccact
    63001 gggatgggga ttattatgta aaggatgatg gttctaaagc tcaaagtgaa tggatttttg
    63061 acaactacta taaggcttgg ttttatatta attcagatgg tcgttactcg cagaatgaat
    63121 ggcatggaaa ttactacctg aaatcaggtg gatatatggc ccaaaacgag tggatctatg
    63181 acagtaatta caagagttgg ttttatctca agtcagatgg ggcttatgct catcaagaat
    63241 ggcaattgat tggaaataag tggtactact tcaagaagtg gggttacatg gctaaaagcc
    63301 aatggcaagg aagttatttc ttgaatggtc aaggagctat gatgcaaaat gaatggctct
    63361 atgatccagc ctattctgct tatttttatc taaaatccga tggaacttat gctaaccaag
    63421 agtggcaaaa agtgggcggc aaatggtact atttcaagaa gtggggctat atggctcgga
    63481 atgagtggca aggcaactac tatttgactg gaagtggtgc tatggcgact gacgaagtga
    63541 ttatggatgg tgctcgctat atctttgcgg cctctggtga gctcaaagaa aagaaagatt
    63601 tgaatgtcgg ctgggttcac agaaacggta aacgctattt ctttaataat agagaagaac
    63661 aagtgggaac cgaacatgct aagaaaatca ttgatattag tgagcacaat ggtcgtatca
    63721 atgattggaa aaaggttatt gatgagaacg aggtggatgg tgtcattgtt cgtctaggtt
    63781 atagcggtaa agaagacaag gaattggcgc ataacattaa ggagttaaac cgtctgggaa
    63841 ttccttatgg tgtctatctc tatacctatg ctgaaaatga gaccgatgct gagaatgacg
    63901 ctaaacagac cattgaactt ataaagaaat acaatatgaa cctgtcttac cctatctatt
    63961 atgatgttga gaactgggaa tatgtaaata agagcaagag agctccaagt gatacagaca
    64021 cttgggttaa aatcatcaac aagtacatgg acacgatgaa gcaggcgggt tatcaaaatg
    64081 tgtatgtcta tagctatcgt agtttattac agacgcgttt aaaacaccca gatattttaa
    64141 aacatgtaaa ctgggtagcg gcctatacga atgctttaga atgggaaaac ccttattatt
    64201 caggagaaaa aggttggcaa tatacctctt ctgaatacat gaaaggaatc caagggcgcg
    64261 tagatgtcag cgtttggtat taagcgatga tttgaaagag ggatgtgata gtagcaccct
    64321 ctttttcttt gttttatgat agttcatcct cgagtaaatt caagatcttg ctcggaaatg
    64381 aagcttatat agtagattga atatagacaa ataccttgtg attggtaaaa cattttagaa
    64441 attcatttac ctttcctaat cgacttggtt tcatcttatt tcaatctatt atagtattgg
    64501 ggaatttctt caaaccacat cagcttggtc agttctacct gcgacctcaa aacttgtgct
    64561 ttggtcaagc tgggtttagt ttcctagttt gctgatggat ttccattgac tataagcatc
    64621 caaccctctt tttgtcttct aaagaattct taaattatca gtctattgca acttttctca
    64681 tataagttct ttgtcttgct atttgttttc cttagtagta tactaaggta gtaatcatta
    64741 agaagtggtt acaaaaaata atgaatgagg taaagaaaat ggtagaattg aaaaaagaag
    64801 cagtaaaaga cgtaacatca ttgacaaaag cagcgccagt agcattggca aaaacaaagg
    64861 aagtcttgaa ccaagctgtt gctgatttgt atgtagctca cgttgctttg caccaagtgc
    64921 actggtatat gcatggtcgt ggtttccttg tatggcatcc aaaaatggat gagtacatgg
    64981 aagctcttga cggtcaattg gatgaaatca gcgaacgctt gattacactc ggtggaagcc
    65041 cattctctac attgacagag ttccttcaaa atagtgaaat cgaagaagaa gctggtgaat
    65101 accgtaatgt tgaagaaagc ttggaacgtg ttcttgttat ctaccgttac ttgtcagaac
    65161 ttttccaaaa aggtttggat gtcactgatg aagaaggtga cgatgtgaca aacggtatct
    65221 ttgcaggcgc taaaactgaa acagataaaa caatttggat gcttgcagcc gaacttggac
    65281 aagcacctgg tttgtaagaa ataaggaaac atagataaat ctgtaggaaa tttcttacag
    65341 attttttcta ttttgtaagc tattccaaac cagtcttttt ttgagttttt tgataaaata
    65401 gtactatcag tgaaaaggat ggaagcatga ctaagaaaat cgtagctatt tgggcccagg
    65461 atgaagaggg tgtgattggt aaggaaaatc gtctgccttg gcatttgcca gcagaattgc
    65521 agcactttaa agaaacaact ctgaatcatg ctatcttgat ggggcgtgtg acctttgatg
    65581 ggatggggcg tcgcttgctt ccaaaacggg aaaccctgat tttgacgcgt aatccggaag
    65641 aaaagataga tggggttgct acttttcagg acgtccagtc tgttcttgac tggtatcagg
    65701 atcaagaaaa gaatctctac attatcggtg ggaagcaaat ttttcaggct tttgaacctt
    65761 accttgatga agtgattgtc actcacattc atgctcgggt ggaaggagat acctatttcc
    65821 ctgaagagct tgacttgtct ctttttgaga cagtttcaag caaattttac gccaaagatg
    65881 agaagaatcc ttatgatttt accatccaat accgcaagag aaaggaagta taatggaacg
    65941 gagtttattt ggtctattca cggcttttct gtgtttcatc tgctttctgg caggagcaca
    66001 ggcttttcgt aaaaagcgtt acgggctttc tatcctcctt tggttaaatg cctttaccaa
    66061 tctggtcaat agtattcatg ctttttacat gaccttattt tagatagaat gacagtatag
    66121 aatggaagga aatcatgtct acaaatagaa aaaatgatat gatggtttat tgctcatttt
    66181 gtggcaaaaa ccaagaagaa gtacaaaaaa taattgctgg caacaatgct tttatttgta
    66241 atgaatgcgt ggagttagct caggaaatca ttcgagaaga attggttgag gaagtcttgg
    66301 cagacttgtc tgaggtgcca aaaccaattg aactcctcca tatcttgaac cactatgtaa
    66361 ttggtcaaga tcgtgccaag cgtgccttgg cagtggcggt ttataaccac tacaaacgca
    66421 tcaatttcca cgatacacgc gaagagtcag aagatgtgga tttgcagaag tcaaacattt
    66481 tgatgattgg cccaactggt tcagggaaaa ctttccttgc ccagaccttg gctaagagct
    66541 tgaatgtgcc ttttgctatt gcggatgcga cagctctgac ggaggctggt tatgtgggtg
    66601 aggacgtgga aaatatcctc ctcaaactct tgcaggttgc tgactttaac atcgaacgtg
    66661 cagagcgtgg cattatctat gtggatgaaa ttgacaagat tgccaagaag agtgagaatg
    66721 tgtctatcac acgtgatgtt tctggtgaag gggtgcaaca agcccttctc aagattatcg
    66781 agggaactgt tgctagcgtg ccgcctcaag gtggacgcaa acatccacaa caagagatga
    66841 ttcaagtgga tacaaaaaat atcctcttca tcgtgggtgg tgcttttgat ggtattgaag
    66901 aaattgtcaa acaacgtctg ggtgaaaaag tcatcggatt tggtcaaaat aataaggcga
    66961 ttgacgaaaa cagctcatat atgcaagaaa tcatcgctga agacattcaa aaatttggta
    67021 ttatccctga gttgattgga cgcttgcctg tttttgcggc tcttgagcaa ttgaccgttg
    67081 atgacttggt tcgcatcttg aaagagccaa gaaatgcctt ggtgaaacaa taccaaactt
    67141 tgctttctta tgatgatgtt gagttggaat ttgacgacga agcccttcaa gagattgcta
    67201 ataaagcaat cgaacggaag acaggggcgc gtggacttcg ctccattatc gaagaaacca
    67261 tgctagatgt tatgtttgag gtgccgagtc aggaaaatgt gaaattggtt cgcatcacta
    67321 aagaaactgt cgatggaacg gataaaccga tcctagaaac agcctagagg tgactatgga
    67381 acttaataca cacaatgctg aaatcttgct cagtgcagct aataagtccc actatccgca
    67441 ggatgaactg ccagagattg ccctagcagg gcgttcaaat gttggtaaat ccagctttat
    67501 caacactatg ttgaaccgta agaatctcgc ccgtacatca ggaaaacctg gtaaaaccca
    67561 gctcctgaac ttttttaaca ttgatgacaa gatgcgcttt gtggatgtgc ctggttatgg
    67621 ctatgctcgt gtttctaaaa aggaacgtga aaagtggggg tgcatgattg aggagtactt
    67681 aacgactcgg gaaaatctcc gtgcggttgt cagtctagtt gaccttcgtc atgacccgtc
    67741 agcagatgat gtgcagatgt acgaatttct caagtattat gagattccag tcatcattgt
    67801 ggcgaccaag gcggacaaga ttcctcgtgg taaatggaac aagcatgaat cagcaatcaa
    67861 aaagaaatta aactttgacc cgagtgacga tttcatcctc ttttcatctg tcagcaaggc
    67921 agggatggat gaggcttggg atgcaatctt agaaaaattg tgaggaaaag aaaatggcaa
    67981 aaacaattca tacagataag gccccaaagg ctatcggacc ctatgttcaa ggaaaaatcg
    68041 ttggcaacct tttgtttgct agcggtcaag ttcccctatc ccctgaaact ggggaaattg
    68101 taggagagaa tatccaagaa cagacagagc aagtcttgaa aaacatcggt gctattttgg
    68161 cagaagcagg aacagacttt gaccatgttg tcaaaacaac ttgtttcttg agcgatatga
    68221 acgactttgt tccttttaat gaggtttacc aaacggcctt caaagaggaa ttcccagctc
    68281 gttcagctgt ggaggtagct cgtcttcctc gtgatgtaaa agtcgaaatt gaagtcatcg
    68341 cagagattgg ataagctagt tgaagtttgg tgttgccaaa cttcttttga tataaggaga
    68401 aaaagatgac aaagaaacaa cttcacttgg tgattgtgac agggatgagt ggcgcaggga
    68461 aaactgtagc cattcagtcc ttcgaggatc taggttattt caccattgat aatatgccgc
    68521 cagctctctt gcctaagttt ttgcagctgg ttgaaattaa ggaagacaat cctaagttgg
    68581 ccttggtagt ggatatgcgt agccgttctt tcttttcaga gattcaagct gttttggatg
    68641 agttggaaaa tcaagatggt ttggatttca aaatcctctt tttggatgcg gctgataagg
    68701 aattggtcgc tcgttacaag gaaaccagac ggagtcaccc actagcagca gacggtcgta
    68761 ttttagatgg aatcaagttg gaacgtgaac tcttggcacc tttgaaaaat atgagccaaa
    68821 atgtggtgga tacgactgaa ctcactccac gtgagctgcg caaaaccctt gcagagcagt
    68881 tttcagacca agaacaagcc cagtctttcc gtatcgaagt catgtctttc ggatttaagt
    68941 atggaatccc gattgatgcg gacttggtct ttgatgtccg tttcttgcca aatccctatt
    69001 atttaccaga actgagaaac caaacgggtg tggatgaacc tgtttatgat tatgtcatga
    69061 accatcctga gtcagaagac ttttatcaac atttattggc cttgattgag ccgattctgc
    69121 caagttacca aaaggaaggt aagtccgttt tgaccattgc catgggatgt acgggtggac
    69181 aacaccgtag tgtggcattt gctaaacgct tggtgcagga cttatccaag aattggtctg
    69241 ttaatgaagg gcatcgcgac aaagaccgca gaaaggaaac ggtaaaccgt tcatgagaaa
    69301 accaaagata acggtgattg gtggagggac tggaattccc gtcattctaa aaagtctgcg
    69361 ggaaaaagat gtggaaatcg cagctatcgt gacggtggca gatgatggtg gttcttcagg
    69421 tgaactccga aaaaatatgc aacagttgac accgccaggt gattttcgta atgtccttgt
    69481 ggccatgtcg gatatgccta agttttatga gaaggtcttt cagtatcggt tctctgagga
    69541 tgccggagcc tttgctggcc atccattggg aaatctcatc attgctggct tgtcagaaat
    69601 gcagggttca acctataatg ccatgcagtt attgagcaaa tttttccata caacagggaa
    69661 aatttatcct tccagtgacc atcctttgac ccttcatgca gtctttcagg atgggacaga
    69721 agtggctgga gagagtcata ttgtagacca tcgaggcata attgacaatg tctatgtgac
    69781 caatgcccta aacgatgata cgcctctggc cagccgtcga gtagtgcaga ccatccttga
    69841 aagtgacatg attgtcctag ggccaggttc tctctttacc tctattttgc ccaatatcgt
    69901 gattaaggaa attgggcggg ctcttttgga aaccaaggca gaaattgcct atgtctgcaa
    69961 tatcatgacc caacgtgggg agacggaaca ctttacagat agcgaccacg tggaagtctt
    70021 gcatcgtcac cttggtcgcc cttttatcga cactgtcttg gtgaatattg aaaaagtgcc
    70081 tcaggaatac atgaattcca accgttttga tgaatacttg gtgcaagtgg aacacgattt
    70141 tgtaggtctt tgtaagcaag tttcgcgcgt gatttcatct aacttccttc gtctggaaaa
    70201 tggcggtgcc ttccacgatg gagatttgat tgtggacgag ttgatgcgca ttatacaggt
    70261 gaaaaaatga gtttcacagt agcagtaaaa gaagaaatcc tgggccaaca ccatctgagc
    70321 tggcatgaat tatctgccat tatcaaaatg tctggtagca tcggtctctc gacttcgggc
    70381 ttgactttgt cagttgtgac agaaaatgcc aaactggccc gtcacctcta tgagtccttt
    70441 ctccatttct atgaaatcaa atctgaaatt cgtcaccacc aacggagcaa tcttcgcaag
    70501 aatcgcgtct ataccgtttt tacagatgaa aaggtgcagg atttgttaag tgatttgcac
    70561 ttggcagact ctttctttgg cctggaaaca ggtattgatg aggcgatttt atcggatgag
    70621 gaagcaggtc gtgcctatct ctgtggcgct ttcttggcaa atgggagcat tcgtgaccct
    70681 gagtcaggca agtaccagtt ggaaatcagt tctgtttatc tggaccacgc gcaaggaatt
    70741 gcctcccttc tccaacagtt tttactggat gccaaggtgc ttgagcgcaa gaagggggct
    70801 gtgacctatc tccagcgagc agaagacatt atggacttct tgatagtaat cggagccatg
    70861 caggcacgtg atgattttga gcgggttaag attttgcgag aaacccgtaa cgacctcaat
    70921 cgggctaata atgccgagac agctaatatc gctcggacag tttctgccag catgaagacc
    70981 attaacaata tcagtaaaat aaaagatatc atgggcttag aaaatttgcc agtagatttg
    71041 caggaagtgg cgcaactgag gattcagcac ccagactact ctatccaaca gttggcagat
    71101 agcctcagca cccctctgac caaaagtggt gtcaatcaca gactcagaaa aatcaataag
    71161 atagccgatg aattataaaa ccacgaatcc tatgtgactc gtggttcttt tttataaact
    71221 agtagagtgt tttggttgta ctttttgttc agggtcaatg tagttgatag cgttgttgac
    71281 agcagttgga gcttctccga ggcctgtcgc aatcagatca atttttccgt catagtagca
    71341 gcagtcaccg atagcataga tacctgcttg gctggattcc tgtttgctgt tgacgataat
    71401 cttgtgacgg ttgaggtcga gcccccagtt tttaaggtta ccgacagaag atttgaaacc
    71461 atagttgaca aagaggtggt ctaggtcaat ggtttcagtt tcatcagatt tgacttttgt
    71521 gatttcaagt ttatcaagtg tttttccatt tccaaggagt tggctagggg cgaatggtgt
    71581 cttgatggtt acagatgatt cttgcaaggc ttgaacactg tgttccaagg cacggaaatt
    71641 atctctgcgg tgaacaaggg tagttggtgc gattttttca aaagccaaag cccaatccac
    71701 agccgagtct cccccaccaa gaatcgtcac tttcttacca gcgtattgct gaatgttaga
    71761 aacgtggtag tggatatttt catagccctc aacactttca agttccagcg gacgtggttt
    71821 gaaggcaccg ccacccatag cgatgataac tgttttagtc aggtgacttc ctttagaagt
    71881 tgtgatggca aattcttctt cttgtttgtc aatctcaaga accgtttcat tgagatgaat
    71941 aggggtatca aatccattta gctgttcaat caagcggtta gtcaactctt ctccagtcag
    72001 gtttgggaag cctggtacgt ctaggatttc cttttcaggg tagagaatag caggttgtcc
    72061 acctagctgg ggaagagagt cgatgatttg aaccttggct tggcgtaggt gggcataaaa
    72121 ggctgcaaaa agcccgacag gaccaccacc cacaatggta atatcataga gttgagacat
    72181 agtttctcct ttgttttttc tagtcagttt attttatcat atttttgttc aatgtaaaat
    72241 ggactaggat agggaaaaaa atgccagaaa atggtataat aggacgaaag tgttttgata
    72301 gggaggatat cagggatgaa ttttcaacaa ttatccaatc tgcaatattg gaccagtttg
    72361 tttgcaagtc catggacgat agctatcaat ctgattgata ttttgattgt tgcttatatt
    72421 ttataccatt ttacaaaagc tattgcagga accaagatta tgattttggt acgtggagtt
    72481 ttggtgttta ttttagctca aatccttgca aatatgattg gtttgactac gatttcttgg
    72541 ttaatcaatc aaattattac ttatggggtt attgcggcgg ttgttatctt ctctccagag
    72601 attcggactg gtttggaacg tttgggaaga gcgacagatt tcttttccaa tgcccctatt
    72661 agtgctgagg aacagatgat tcgtgccttt gttaagtctg ttgaatacat gagtcctcgt
    72721 aaaatcgggg ccttggttgc tattcagcgt gtacgtacct tgcaggagta tatgtcgaca
    72781 ggaattccct tggatgctaa gatttctgca gaacttctca ttaacatttt tattcccaac
    72841 actcccctac atgacggtgc ggtgattatc aaagaagaac gtatcgctgt gacgtctgcc
    72901 tatctgccct tgacaaaaaa cacagggatt tccaaggaat ttgggaccag acaccgggcg
    72961 gctatcggtt tatcagaagt ctcagatgcc ttgacttttg tcgtatcaga ggaaacggga
    73021 ggaatttcga taacctataa tggaaggttt aagcacaacc taacacttga tgaatttgaa
    73081 acagaattac gtgaaatctt acttccaaaa gaggaagtgg gtcttagttt taaagaacga
    73141 ttgctaggag gatggaaaca tgaaaaaaaa tagtttatat atcatatcct cactcttttt
    73201 tgcttgtgtc ttatttgtct atgctacggc gacgaatttt caaaacagta ccagtgctag
    73261 gcaggtaaaa acggaaacct atactaatac agtaacaaat gtccctattg acatacgcta
    73321 taatagtgat aagtatttta ttagcggttt tgcttcagaa gtatcagtgg tcttgactgg
    73381 tgcaaatcgc ctatcgctag ctagtgaaat gcaagaaagt acacgtaaat tcaaggttac
    73441 tgctgaccta acagatgccg gtgttggaac gattgaagtt cctttgagca ttgaagattt
    73501 acccaatggg ctgaccgctg tggcgactcc gcaaaaaatt acagtcaaga ttggtaagaa
    73561 ggctcaaaag gataaggtaa agattgtacc agagattgac cctagtcaaa ttgatagtcg
    73621 ggtacaaatt gaaaatgtca tggtgtcaga taaagaagtg tcgattacga gtgaccaaga
    73681 gacattggat agaattgata agattatcgc tgttttgcca actagcgaac gtataacagg
    73741 taattacagt ggttcagtac ctttgcaggc aatcgaccgc aatggtgttg tcttaccggc
    73801 agttatcact ccgtttgata caataatgaa ggtgactaca aaaccagtag caccaagttc
    73861 aagcacatca aattcaagta caagcagttc atcggagaca tcttcgtcaa cgaaagcaac
    73921 tagttcaaaa acgaattaaa aatagaaaag gattttataa caatgggtaa atattttggg
    73981 actgatggag tccgtggaga agctaaccta gaactaacac cagaattagc ctttaaacta
    74041 ggacgttttg gaggctatgt tcttagtcaa catgaaacgg aagcgccgaa agtctttgta
    74101 ggacgtgaca cacgtatttc aggggaaatg ctggaatcgg ccttggtggc aggtctcctt
    74161 tcagtaggga ttcacgtata caaacttggt gtccttgcaa caccagcagt agcttacttg
    74221 gttgaaactg aaggagcaag tgccggtgtc atgatttctg ctagccacaa cccagccctt
    74281 gataacggaa tcaagttctt tggcggtgat ggcttcaaac tagatgatga aaaagaagca
    74341 gaaattgaag ccttgctaga tgctgaggaa gacactcttc ctcgtccaag tgcagaaggc
    74401 ttaggaattt tggtagatta tccagaaggc ttgcgtaagt atgaaggata ccttgtttca
    74461 actggaactc ctcttgatgg aatgaaggtt gccttggata cagctaatgg agcagcttct
    74521 accagtgccc gtcaaatctt tgcagacctt ggtgcccaat tgacggttat cggggaaaca
    74581 ccagacggtc ttaacatcaa ccttaatgtt ggttcaacac atccagaagc ccttcaagaa
    74641 gtggtcaaag aaagtgggtc agctattggt ttggcctttg atggagacag tgaccgcttg
    74701 attgctgttg atgagaatgg taacatcgtc gatggtgaca agattatgta catcatcgga
    74761 aaataccttt ctgaaaaagg acaattggct caaaatacaa ttgtgacaac tgttatgtct
    74821 aaccttggtt tccacaaggc cttgaatcgc gaaggtatta acaaggcagt tactgcagtt
    74881 ggtgaccgct acgttgttga agaaatgaga aaatcaggct acaaccttgg tggtgaacag
    74941 tctggtcacg ttatcttgat ggattacaat accacaggtg atggtcaatt atcagcagtt
    75001 caattgacta aaatcatgaa ggaaactggt aagagcttat cagagttggc ggcagaagta
    75061 acgatttatc cacaaaaatt agttaatatc cgagtggaaa acgtcatgaa ggaaaaggcc
    75121 atggaagtgc cagctatcaa ggccatcatc gagaagatgg aagaagaaat ggcggggaac
    75181 ggccgtatcc ttgttcgtcc aagtggaaca gaacccctct tgcgtgttat ggcagaagcg
    75241 cctacaacag aagaagtaga ctactatgtt gataccatca cagatgtagt tcgtgctgaa
    75301 attgggattg actaaatcct agaaaactag atgaaaataa aaaattatgg tacaatagct
    75361 tataatattg tagccgatgg agaaagacat gaatcttaaa cgtgaacaag aatttgttag
    75421 tcagtatcat tttgatgcgc gtaattttga atgggaaaat gaaaatggag ctcctgaaac
    75481 caaggtggat gtgaatttcc aattgctcca acatgaccaa gaaaatcaag tgacttcctt
    75541 gattgtcatc ttgagcttta tgattgtatt tgataagttt gtcattagtg gaacaatctc
    75601 acaagtaaac catatcgatg gccgtattgt caatgaacca agtgaattga accaagaaga
    75661 ggtggaaacc ttggctcgtc catgtttgaa catgctcaat cgtttgactt acgaagtgac
    75721 tgaaattgca ttagacttac caggaattaa tttggagttc taatatgaaa ttagctgttt
    75781 tcacagattc ctctgcttat ctcagtgaag agaccttgca aagagaagac ttgtttgtct
    75841 tggatattcc tgtcaatatt gatggtgagg aatatgtcga aggcatcaat ctgtctgctg
    75901 aggaatttta ccaaaaaatg gctcaggctt ctgaattgcc taagaccagt caaccaagta
    75961 ttgccaagtt agatgagatc ttaacttcgc tcaaagaaca aggctataca catgccttgg
    76021 ggcttttcct atcttctgga atttcaggtt tttaccaaaa tatccagtat atggtcgatg
    76081 actatgaggg cttaaccatt gctttcccag acactttgat tacaagtgct cccctaggca
    76141 tcatggttga aagcgtcttt aattggcgtg atcagggcga tgattttgcc agcattcagg
    76201 ataagctagc cattcaaatc agccgtacgt cagcctttat catggtagat gacttggatc
    76261 atttggtaaa aggtggacgc ctttcaaatg gggctgccat tttgggcaat ttgcttagca
    76321 ttaagccaat cctttatttt aacgatcaag gtgtgattga agtttacgaa aaagttcgta
    76381 ctgaaaagaa ggccaccaag cgcttaattg aaattatcaa ggaaacaacg gcttcaggtc
    76441 aataccgggt cattgtcatt catgggaatg ctcctgaaaa ggctgaagaa ttgcgtcagc
    76501 acttgcttga ttttggcttg ggttcggatg tttcacttgc tacatttggt agtgtcattg
    76561 gaacgcacct aggagcagga agtattgctc tgggttatat tccagtgatt tagttggcgc
    76621 ttctaggcta gttaagatgc cttgtatctt agaaattgaa cacggactac ctgcctcttg
    76681 aaaaaagatg cctgtcttgc ctttcgtgga aagtcagtgc cattccctat ttttcagagg
    76741 cagctaaggt cctttgtatc ttgataattg aacacgcctg gaaccctgtg tgaaaaagat
    76801 agttcttcca agaagtagac acttcttgat tggaattcct attttcactt tgtgttctta
    76861 cggactttgt atcttagaca ggagtagaga tgagtattcg agtaattatt gccggtttta
    76921 agggaaagat gggccaggct gcttgtcaga tggtattgac tgatccagac ttggacttgg
    76981 tagcagtttt ggatcctttt gagtctgagt cagaatggca gggtattcct gttttcaagg
    77041 ataaggctga tttagctggt tttgaagcgg atgtctgggt agattttact actccagctg
    77101 ttgcctacga aaatacacgt tttgctcttg aaaatggctt tgctccagta gttggaacga
    77161 ctggtttcac gagtgaagaa attgcagagc taaaagaatt ttctcgtgcc caagacttgg
    77221 gtggcctgat tgcccctaac tttgccttgg gtgctgtctt actcatgcaa tttgcgacgc
    77281 aggctgccaa atatttccca aatgtggaga ttattgagct ccatcatgac aagaaaaagg
    77341 atgctccgag tggaacagcc attaaaacag ctgagttgat ggcagaggtt cgagagtcca
    77401 ttcagcaagg cgcagcagat gaggaagagc tgattgctgg tgctcgtggt gctgactttg
    77461 atggtatgca catccactca gttcgtttgc caggtttggt agcccatcag gaagtcatct
    77521 ttggcaatca gggagaaggg ttgaccctcc gtcatgactc ctatgatcgc atctccttca
    77581 tgacaggagt caatttggga attaaagaag ttgtcaagcg tcatgagctt gtctatggat
    77641 tagaacactt attatgagat taacgcaaat gccttctgaa tttcagaagg ctttaccagt
    77701 attagaaaaa attaaagaag caggctttga ggcttatttt gttgggggct ctgttcgaga
    77761 tgcccttctc cataacccta tccacgatgt ggatattgcg acgtcttctt atccagaaga
    77821 gaccaagcag atttttccgc gaacagccga tatcggaatc gagcatggaa ccgtcttggt
    77881 cttagatggg gatgaggagt atgaggtaac aacctttcgg acagaggatg tctatgtgga
    77941 ctatcgcaga cccagtgcgg tttcctttgt gcgctcgcta gaagaagacc tcaaacgccg
    78001 tgatttcaca gtcaacgcct ttgccttgga tgagacagga gaaatcgttg acttgttcca
    78061 tggtttagaa gatttggaaa agcaagtctt gcgagcagtt ggagtggcta gtgagcgttt
    78121 caacgaagat gctttacgga ttatgcgtgg tttccgtttt caggctagtc ttggttttgc
    78181 acttgaacca gaaacattta aagctatgaa gaccttgacg ccgcttttgg agaacatttc
    78241 tgtagagcgt accttcgtcg agtttgataa actcttgctg gctccatttt ggagaagggg
    78301 cttggcttcc atgattgaga gtcaagctta tgactatctc cctgatatgg catctagcca
    78361 ggacaagctc aacagactgt ttgatttgga gactgatttt acttttgaat cctctgaaca
    78421 agcctgggcg gctttactat gggctttgga gattgaaaat gcgcagtcat ttttgaaatc
    78481 ttggaagacc tcacgccagt ttgccaagca agttcaggat ttgctgatta ttttggctct
    78541 gcgtgaaaat ggagaattga gcaagcgaga ttgttatcgc tttgacatag atttgctttt
    78601 acaggctgaa aatcttcgtc aagctcaagg aaaagaagtc aacccacaag ccatcacaga
    78661 aaaataccaa agcttgacta tccatgacaa gaaagagatt cagattaatg gcggtatttt
    78721 gatcaaggaa tatggctatc agccaggccc agacttggga gagattttaa cagagattga
    78781 gtttgccatt gtcgatggag aattggagaa taatcgtgaa gccatccatg cttacctgag
    78841 ggagaaaaaa tgagtgattt tatcgttgaa aaactaagta aatccgttgg tgacaagacc
    78901 gtttttaggg atatttcctt tattatccat gacttagaca gaattggttt aatcggtgtc
    78961 aatgggactg gcaagaccac ccttttggac gtcctttctg gtgtttctgg atttgatggg
    79021 gatgtcagtc ctttttcagc taaaaatgat taccagattg gttacttgac tcaggatcct
    79081 gattttgatg atagaaagac agttttggat acggttctat ctagtgaact caaggaaatc
    79141 cagctcattc gtgagtatga attgattatg ctcgactata gtgaggacaa gcaggcgcgt
    79201 ttggaacgtg tcatggcaga gatggactct ctccaagctt gggaaatcga aagtcaggtc
    79261 aagaccgttc ttagcaaatt gggcattcaa gacttatcta ctcctgttgg ggaattgtca
    79321 ggtggtctga gaagacgggt acagttggca caagtcttac ttggcaacca cgacctcttg
    79381 cttttggatg agccgaccaa ccatctggat attgcgatta ttgagtggct gaccctcttt
    79441 ttgaaaaatt ctaagaagac cgtccttttt atcactcacg atcgttattt cttagacgct
    79501 ttgtcaacac ggattttcga gttggatcgt gcaggcttga ccgagtacca gggaaattac
    79561 caggactatg ttcgcctaaa ggcggaacag gatgagcgcg acgcggctct tcttcacaaa
    79621 aaagaacaac tctacaaaca agaattggcc tggatgcgca gacaaccgca ggcgcgtgcg
    79681 accaagcagc aggcccgtat caatcgattc catgatctga aaaaggaagt ttcaggcagt
    79741 agtgctgaga cagacttgac catgaacttt gaaaccagtc ggattgggaa gaaagtcatc
    79801 gagtttcagg ctgtttcctt tgcctatgaa aacaagccta ttttgcaaga ttttaatctc
    79861 ttggtgcagg ccaaagaccg tatcggaatc gttggggaca atggtgttgg aaaatcaacc
    79921 ctgctcaact tgattgcagg aagtcttgag ccaactaaag gacaagttgt gattggggaa
    79981 actgttcgca tcgcctattt ctctcagcaa attgagggtt tggatgaaag caagagagtt
    80041 atcaattacc tgcaggaagt ggcagaagag gtcaagacca gtggcggttc tacgacttcg
    80101 attgcagagt tgctggagca gttccttttc ccacgttcga cgcatggaac cttgattgag
    80161 aaattgtcag ggggtgagaa aaaacgtctt tatctcctca aactgctttt ggaaaaacca
    80221 aatgttcttc ttttagacga gccaaccaat gacctagata ttgcaacttt gacagtctta
    80281 gagaatttct tgcaaggttt tgcaggtccc gttttaacag tcagtcacga ccgctatttc
    80341 ttggataagg tagcgaccaa gattctcgct tttgaggatg gcaagattcg tcctttcttt
    80401 ggtcattaca ccgactatct tgatgaaaaa gcttttgaaa cagatatggc caatcaagtg
    80461 caaaaggtcg aaaaggaaaa agtggtcaag gttcgagaag acaagaaacg catgacctac
    80521 caagaaaagc aggagtgggc aagtattgaa ggtgatattg aaaccttgga aaaacgtatc
    80581 gctgctattg aagaggaaat gcaggctaac ggctctgact ttggtaagct ggctactctc
    80641 caaaaagaat tggatgagaa aaatgaagca ctccttgaaa aatacgaacg ctatgagtat
    80701 ctcagtgaat ttgatagtta agactattcg aaaatcaaag tgcaaactat gtcggcttca
    80761 cattgccgac tcaagtacag cctgtgaccg gcttcctaat ttgcactttg atttttattg
    80821 agtataaacg aatagaaaaa tcccgtctca tgaaaggatt tctctattct tttttggttt
    80881 cttgatgaaa gatattttgc caggtttcgt ggcgacgcca gatactggta tggatgatac
    80941 catctaactc atagcagata agtttggttt tttgactgat ggaagtaatt tgaatgtcct
    81001 tgatagcaga atttaactct tttttggtct tataagcctc tttatccatc tgctctccat
    81061 cttggcgaat atagacaaaa tcatcagtca agagttcttc tagttggttt ccttggtcga
    81121 tcaattgttc acgcataagc aattttttat agacattgtc taaaatttca tcctcaggga
    81181 taggtgctgg ttcgatatgg acatcggtat caaagacgcc aaaacgctcc tccagcatag
    81241 actcgacctg atccgcgatt tcatggcttt caaaaacaga caagtcagga ttcatctcta
    81301 gtgtaatatc caggtagatg ttgctaccgt aggtgcgacc tctttgcgat ttgaccttgc
    81361 tgattttggg aatttccatg atagcctttt ggtagtcctc gagcaggcgg tcgtcaaagc
    81421 catctgaaag actaaaggaa gactcgatga agatatcata ggcagtcttc aagataaaga
    81481 aagtgatgat gatagcaacc agtttatcca caatcggata attgaaacta ctagctagga
    81541 tggcaatggc ggttccaagt gaggtaacag cgtcagaaag attgtcctta gcagctgcct
    81601 tcagcgcctt ggagttggat ttcttactga ggcgagtatt gtagagatag accacaaaca
    81661 taatcgctgc agaaatgatt cctagagttg caccaagagg atcaatgacc gtttcttccc
    81721 gactgagaat cttttgaatg gtatctctta gaacatcgaa accgacatag aacatgatga
    81781 tagaagtgat caagcttgcc aaatcttcaa tcttccaatg accaaaacgg tggtcacggt
    81841 ctgcaggctg gcgcgccatc cgaatcccga ttaagagggc cacatttcca atgatgtccg
    81901 atacgttatt aaaaccatcg gccaccaaac tggatgaatg aaggagatga ccagttgcta
    81961 atttggctgc agacaagatc aaataggtcg aaatactgat aatggctcca cgctcagcta
    82021 acttgagatt tgagatagat tgcttcattc aacttccttt ctagtcacat agcattctac
    82081 cattatactg gttttcaagg aaaaattcaa ataaggcagt ttttactctt tgaaaactcc
    82141 ccaaaatttg gtataatggt actactcaag ggagtagctg gcagaaacct gtgatagtgt
    82201 cgtcattccg aattttatgc tgaaaagtat gctttccggc cctatcttaa acagcgagac
    82261 ttgttatgat taacaggtct ctttttgttt gtcgtgaaaa gatatgacag aaagagagtc
    82321 tgttttgcac acaatgtcaa ggaggagaca catgtcaaaa gaacaaaaac gccaagcgtt
    82381 ttatactcag agccctgaag aggtcttgca ggctgtggat gcgaccgagc aaggtttgtc
    82441 atcaagtgag gcggaaaagc gccttgccga atttgggcac aatgaactcg aagaaggcga
    82501 gaaacgatca atcttggtca aattcatcga gcaatttaag gatttgatga ttatcatcct
    82561 agttgcggca gcaatcttgt cagtcgtgac ttctggtggg gaagatatcg cagatgccat
    82621 tatcatccta gctgtggtta tcatcaacgc tgcctttggt gtttaccaag aaggaaaagc
    82681 tgaagaagct atcgaagccc tcaaatccat gtctagtcca gttgcccgcg ttcttcgtga
    82741 tggacacatg gcagagattg actctaaaga attggtacca ggcgatatcg ttgcccttga
    82801 agcaggtgac gtggtaccag cggacctacg tttgctagaa gccaactctc ttaaaattga
    82861 agaagcagcc ttgacaggtg aatctgtacc agtcgaaaaa gacttgtcag tcgatcttgc
    82921 gacagatgct ggtattggtg accgtgtcaa catggccttc caaaactcaa acgtaaccta
    82981 tggtcgtggg atgggtgttg ttgtcaatac aggtatgtat actgaagttg gtcatattgc
    83041 tggtatgctt caagatgcgg atgagactga tacaccactc aaacaaaact tgaacaacct
    83101 ttctaaggtc ttgacctatg ctatcttggt cattgccctt gttacttttg tagtgggtgt
    83161 cttcattcaa gggaaaaatc cacttggtga gttgttgact tctgttgccc ttgccgttgc
    83221 agccattcca gaaggacttc ctgctatcgt taccatcgtt ctttctcttg gtactcaagt
    83281 tttggccaaa cgacattcca tcgttcgtaa gttgccagca gttgaaacac ttggttcaac
    83341 tgaaatcatc gcttctgata agactggtac gctgactatg aacaagatga cagtcgaaaa
    83401 agtcttctac gatgcggttc tacatgactc agctgatgat attgaactag gtcttgaaat
    83461 gccactactt cgttcagttg tcttggccaa tgatacgaaa atcgatgtgg aaggtaactt
    83521 gattggtgac ccaaccgaaa cagcctttat ccaatatgcc ttggacaagg gctatgatgt
    83581 caaaggtttc ttagagaaat atcctcgtgt agctgaattg ccatttgact ctgaccgtaa
    83641 gctcatgtca acagttcacc cattgccaga tggtcgtttc cttgtagcag tcaagggtgc
    83701 gccagaccaa ctcttaaaac gttgtcttct tcgtgataag gctggggata ttgctccgat
    83761 tgatgagaag gttacaaatc tcattcatac aaacaattct gaaatggctc atcaagcctt
    83821 gcgtgtcctt gcaggtgctt ataagattat cgatagtatt ccagaaaatc tcacttctga
    83881 agagcttgaa aatgatttaa tttttactgg tttgattggg atgattgacc ctgaacgtcc
    83941 tgaagccgct gaggctgttc gtgtggctaa ggaagcggga atccgtccaa ttatgattac
    84001 aggtgaccac caagacacag cggaagccat tgccaaacgt ttgggaatca ttgacgcaaa
    84061 cgatacagaa ggtcacgttt taactggtgc tgaactcaat gaactgtcag atgaagaatt
    84121 tgaaaaagtc gttggtcaat actctgttta tgcccgtgtg tctccagaac acaaggttcg
    84181 tatcgtcaag gcttggcaaa aacaaggtaa agtcgttgcc atgacaggtg acggtgtcaa
    84241 tgacgcgcca gctctgaaaa cagccgatat cggtatcggt atgggaatca ctggtacaga
    84301 ggtttctaag ggggcttctg acatgattct tgcagatgat aactttgcga ctattatcgt
    84361 cgcagtggaa gaaggacgta aggtcttctc aaacattcaa aagactattc agtacctact
    84421 ttctgctaat actgctgaag tattaaccat cttcctatca accttgtttg gttgggatgt
    84481 cttgcagccg gttcatcttt tgtggatcaa cttggtaacg gataccttcc cagctatcgc
    84541 tcttggtgtt gaacccgcgg agcctggtgt catgaatcat aaaccacgtg gacgcaaggc
    84601 aagcttcttc tcaggtggtg ttttgagttc tatcatttat caaggtgtac tccaagcagc
    84661 tcttgttatg agtgtttatg gccttgcgat tgcttaccca gttcatgtgg gtgacaatca
    84721 tgctattcat gcagatgccc taacgatggc ctttgcaacc cttggtttga ttcagctctt
    84781 ccatgcctac aatgtcaagt ctgtctacca atccatcttg acagttggcc cattcaagtc
    84841 taagaccttt aactggtcca tcttggtatc ctttatcctt ctcatggcaa caatcgttgt
    84901 agaaccgctt gaaggaatct tccacgtaac caaactagac ttgtcacaat ggggaattgt
    84961 tatggctgga agcttctcaa tgattatcat cgtcgaaatc gttaagttta ttcaacgcaa
    85021 actcggtttt gacaagaatg cgatttaagg gaggtttcgg atgtcagcat atcaattacc
    85081 gaccgtatgg caggatgaag ctagtaatca aggagctttt acggggctaa acagacaaac
    85141 agcaggtgcc cgtttcgaac aaaacttgcc aaaaggagaa caagcttttc agctttattc
    85201 actgggaaca ccaaatggtg tgaaggttac tatcttattg gaagaattac tagaagctgg
    85261 ttttaaggaa gcggcttacg acttgtataa gattgctatc atggatgggg atcaattcgg
    85321 atcagacttt gtgaagctca atccaaattc caagattcca gccttattgg accagtcagg
    85381 tactgaagat gtaagagtct ttgagtctgc tcatattctt ctttaccttg ctgagaaatt
    85441 tggagccttt ttaccaagta atcctgtgga aaaggtagaa gttttgaatt ggctattctg
    85501 gcaagcaggt gcagcacctt ttctaggtgg gggatttgga catttcttca attatgctcc
    85561 tgaaaaattg gaatatccta ttaaccgttt tacgatggaa gtgaaacgcc agttggattt
    85621 attggataag gaattggctc agaaacctta tattgcaggc aatgactata cgattgcaga
    85681 tattgctatc tggtcttggt atggacagtt agttcaagaa aatctttacc aaggttctgc
    85741 aaaattcttg gatgcctcaa gttatcaaaa tctagtaaaa tgggcagaaa aaattgccaa
    85801 tcgtccagct gttaagcgtg gcttggaagt aacttataca gaaattaaat agcaaaaaag
    85861 tcatcttcgg atggcttttt gctacagttg agggaaaggg tttgcagtta tcggcttttg
    85921 tgctataatt gctataatat agtaaaaagc aagaggagtg tgaggaagtg gaaaagaaaa
    85981 ttgtgaagga taacttattt ttatctcaag tgtctcagcc ggcaagtcag gaggaccttt
    86041 atcttgccag agatttgcag gatacactct tagcaaatcg tgatacctgt gttggtctag
    86101 ctgccaatat gattggggtg cagaagcgcg tgattatctt taatcttggc ttggttcccg
    86161 tggtcatgtt taacccagtg cttctgtcct ttgaaggatc ctatgaggca gaagaaggct
    86221 gtttgtcctt ggtaggtgtg agatcaacta agcgttatga aaccataagg cttgcctatc
    86281 gtgacagcaa gtggcaggaa cagaccatta ccttgacagg cttcccagct cagatttgcc
    86341 agcatgagct ggatcacttg gaaggacgaa tcatttagga ggaaagcaaa tgaaacgaat
    86401 agtctttgaa cttattttta tcgcaacgac ctggtatatc tttttaccgc cccttaacct
    86461 gaccagctgg gaatttctct tcttcctctg tgggcatttg ttagttgtgg caatcttatt
    86521 tggctttggc aaggggataa accttgtcaa aacggttcat gtgcgccacg gtaaggcgga
    86581 agctgcctta aatcttgagg gtttcaaaat caatcggtta gggaaaattc tgttagcttc
    86641 gattggagga attcttctct tggcagcttt ggtttccttg gtaacttcca gcatgtttca
    86701 ggctaaaaat tatgccaatg tagtcacggt tacggaaaaa gactttactg aatttcctag
    86761 gagtgacacc agtaaggttc ctatcctaga tagaagtact gctgaaaaaa ttggagaccg
    86821 ctacttgggt tccctaaccg ataaggtgtc gcaatacgta gcggcagata cctataccca
    86881 attgacaatt gatgggaaac cttatcgggt cacaccacta gaatatgcag accctatcaa
    86941 atggtttaac aatcaagcca agggaatcgg tgagtatatc aaggtggaca tggtaactgg
    87001 aaatgcggat ttggtggact tgaagacacc aatcaagtat tcagactcgg agtattttaa
    87061 ccgtgatgtc aaacgtcacc tgcgcttgaa gtacccgacc aaaatcttta aaactccatc
    87121 ttttgaggtg gacgatgagg gcaatccttt ctatgtagca acggtttacc aaaagcaatt
    87181 tggacttgct gttcctcgtc ctgcttcagt cattatcttg gatgctacaa atggagaaac
    87241 caaggaatac agcttatcag atgttccaga atgggtggac aggatctatc cagcagagga
    87301 aaccattgag caaattaact acaacggcaa gtacaaggac ggtttcttga atgccatgat
    87361 ttccaagaaa aacgtgaccc agactaccaa gggctataat tacttgtcta tcggtaatga
    87421 catctatctc tacacaggtg tgacgtcggc taatgcggat gagagtaatc ttggtttcat
    87481 ccttgaaaat atgcgaacag gagaaatcac taagtatagc ttggcttctg cgacagaaga
    87541 atcagcccgt gaatcagcag aaggtgctgt tcaggagaaa tcctacaaag caaccttccc
    87601 aatcctcatc aacctcaatg acaagcctct ctacatcatg ggcttgaagg acaatgctgg
    87661 cttggtcaaa gagtacgccc tggtagacgc agtcgagtac caaaatgtta tcgttgctac
    87721 tacagtggaa gagatgctca gcaagtatgc caataaaaac gaccttgaaa ttgacaatgc
    87781 aacgacagaa agcatcaatg gagtagtagc agacctcaaa tcagctgtta tcaagggaga
    87841 cactgtctac ttctttaaag ttgatggcaa gatatacaag gtcaaggctt cagtatccga
    87901 tgaccttcct taccttgaaa atggtaaaac cttcgaaggt caagtaggaa aagacaatta
    87961 tctcaagacc tttaaagtac aataatactc ttcgaaaatc tctagctcta tctgcaacct
    88021 caaaacagtg ttttgagcag cctgcggcta gtttcctagt ttgctttttg attttcattg
    88081 agtataaaaa aggtttattt aataaatata tgttataata aggtaaatta agcctaatgg
    88141 aggacaaaga aatgggtttt tatttgatgg ttgcttcaat gctactcgga ctgctcgctt
    88201 tgaagatagg tttttctcag ttcaaggaga aaaaagataa attcttatct atcttaacaa
    88261 gtttagctgg cacagccctt gttctcgtgg ctgtctggtt aggatggccc aaataaatag
    88321 aaaaacctcg gtcaaaccga ggtttttcaa atgaatttct tggttgtggc taaaaaatat
    88381 gctacactat caatatgaaa attttaatcc caacagcaaa agaaatgaac acagacttgc
    88441 caagtatcga ggcaattcct ttaaaaccag aaagtcagac cgtgcttgat gccttggctc
    88501 tctattctgc cagtcaattg gagagtttct acaaggtatc agctgagaaa gcggcggaag
    88561 aatttcaaaa tatccaagct ttgaaaaggc aaactgctca acactatcca gccttgaaac
    88621 tttttgatgg gcttatgtac cgcaacatta agagagataa gctgaccgag gcggaacaag
    88681 attatcttga aaatcatgtc ttcattacct cggctttgta cggtgttgtt ccagccttgt
    88741 cacccatggc tcctcaccgt ttggattttt tgatgaaatt aaaagtcgct ggtaagactt
    88801 tgaagagcca ttggaaggca gtctatgatg aagctctgaa gaaggaagaa gtgattttct
    88861 ctctcttgtc atcagagttt gagactgtat tttctaagga aatcagagca aagatggtga
    88921 ccttcaaatt catggaggat agaggcggtc agctgaagat tcactcaact atctccaaga
    88981 aagcgcgcgg ggcctttcta acagctttaa tagaaaatca agtacaaact gtgggggaag
    89041 cacgtcgctt gaactttgct ggatttgttt accgagaaga tttgtcacaa ccacagggat
    89101 tggtttttgt aaaggaagta tagaaatcag atattttgta tttggcaata tgtatcatca
    89161 gctgttttag tttataaatg agaaaaaaag cgaacaagct agtcttctga gtgtcagaaa
    89221 agtagtcttg ttcgctttta ttatgttata ctcttcgaaa atctcttcaa gccacgtcag
    89281 cgtcgcctta ccgtatatat gtcactgact tcgtcagttc tatctacaac ctcaaagcag
    89341 tgctttgagc agcttgcggc tagcttccta gtttgctttt tgatttttat tgagtgttag
    89401 ttacttgata gcttcgacca agtcttgagc ttgtttttca agtgagttta ggactgtttc
    89461 ttcaagaacc aattttccgt ctgcccaggc agagtcatta acacgtgcag cagtgaaatc
    89521 accaacgcct tgtgtacgga taaatggcaa gaggtctttg tagatagcga aaagttgatc
    89581 gtgccctgca ttggctacag atgatactgt gacaaacttg tcttgaaggg cagaaacgcc
    89641 acgtgtatca gacaagtcaa gggcacgaga tagccagtca agcaagtttt tcactgtacc
    89701 agggatagag aagttgtaga ctggagagaa aatccagata gcatccgcaa cgagaactgc
    89761 ttcacgagcg gcagctacag ctggatgtgt tgggacttcc aaatcttggc tgaagagagg
    89821 gagggctgaa taatcaaggt agctaacttc cgctttacta gcaagtgctt tctcagcttc
    89881 gagcgccatt tggtggttga aagaaccttg acgtagtgat ccgacgataa ataatacttt
    89941 tttagacatg atgtgtctcc tttttcttaa aatttcgaga actctctcgt tgttataaaa
    90001 tatattacaa caaaacaaaa gaacttgcaa gaaatttgct cagagtttat ttgaaaattg
    90061 taaaatttcg gaaactctag tcatttgtga ctgaaaaagt aagaactgtt tcactttcaa
    90121 aatcggtttt gtttgaaggg agaaatagaa ttggttgctc aaagcacagc tttgaggttg
    90181 cagataaagc tgacgtggtt tgaagagatt ttcgaagagt attcttatat tcacttgtaa
    90241 taaagcttaa tagatggtaa aatagacgag tgaaaaaaag acaaaacaaa gcaaaaaata
    90301 atctactgtg gcagtatggt ctagggatga cgattttgtt tgtggttatc agtggttcct
    90361 ttctgtatat ggtttctctt agcatgaaac cctatcaaac agctaaaagt gaaggagaaa
    90421 aattagctca gcagtatgca ggattagagc aggtcgatca ggttgattta tacaatggct
    90481 tggaatctta ttacagcgtt cttggtcgta ataaacagca agaagcgctt gctgtcctga
    90541 ttggtaaaga tgatcataag atttacgttt atcagctaaa tcagggtgtt tcacaagaaa
    90601 aagcagaaac ggtttctaag gaaaagggag ctggcgaaat tgacaagatt atctttggtc
    90661 gttatcaaga taagccaatc tgggaagtca agtcaggatc tgatttttat ctagtagatt
    90721 ttgaaacagg agcattggtc aacaaggagg gcctatggaa ttatccaacc gtgttttaga
    90781 aatggaagaa agtgtgactt tggctgctgg agcccgtgcc aaagcactga aggctgaggg
    90841 tagagatatt ttgtctctaa ccttgggtga gccagatttc actactccca aaaatatcca
    90901 agatgccgcc attgcatcga ttcgagatgg gcgtgcttct ttttatacag taacctcagg
    90961 tctgccagag cttaaggcgg cggtcaatag ctactttgag cgcttttacg gctattctgt
    91021 agcgtcaaat caagtgacag tcgctgcggg agccaaatat tctctctata ccttctttat
    91081 ggctgtggtc aatccaggtg atgaagtcat catcccaacc ccatactggg ttagctatgg
    91141 agatcaggtc aagatggcag aaggcgttcc cgtctttgtt tctgctaagg aagacaatca
    91201 ctttaaggtg accgtagagc agttagaagc agctcgcact gacaagacca aggttttggt
    91261 gctgaattcg ccatctaatc ccacaggtat gatttacacc cgtgaggaac tcttggcaat
    91321 tggaaactgg gctgtagaaa atgatattct catcctagca gatgatatct atggccgctt
    91381 ggtttataat ggtcatgagt tcacaccgat ttctagccta tcggaagcga ttcgcaagca
    91441 aacagtggtc atcaatggtg tgtctaaaac ctatgccatg actggttggc ggattggtta
    91501 tgccgttgga gaagcagaca ttatcgctgc catgtccaag attgcaggtc aaacaacttc
    91561 gaatccgtca gcagtagccc aatatgcagc agttgaggct ctatcaggtg agcaagatac
    91621 tgtagaaagc atgcgtcagg cctttgagga acgtcttaat accatctatc ccctccttgc
    91681 agaagtgcca ggatttgaag tggtcaaacc gcaaggggcc ttctatctct tcccaaatgt
    91741 caaaaaggcc atggagatga aaggctacac ggatgtgaca gactttacaa ctgttatctt
    91801 agaagaagcc gaagtggcct tggtaacagg agctggattt ggagcaccag aaaatgtccg
    91861 cctcagctat gcgacagacc tagacacgct taaagaagca gtcgaacgct tgaaagcatt
    91921 tatgggtagt gagaatgatt gatcattttg agattaaggt aaaggattta caaatttcag
    91981 aaggatttta taggagtttt ctcgctcctt tggactataa attggctttt aagactagtt
    92041 ctctaattag ttttctatcc ccgaacagcc ctcatcctgg tggtgatttt tggctgactc
    92101 agggaacaca agatcctgtt cattttgctt ttttagcaga aaataaggaa gaagttcagg
    92161 cttgttatga ggctggctta gaggcaggtg ggcgagacaa tggggctcct ggttatcgaa
    92221 gtgagcatcc gatttactat gctgctttta tgattgacct ggatgggaac aatatagagg
    92281 tggtttgcca taaagaataa aaaagaaaag gaaaaataat gacaaaacgt gtaacgatta
    92341 ttgacgtaaa agactatgtt ggtcaggaag tgacgattgg cgcttgggtt gccaacaaat
    92401 caggaaaagg gaaaatcgct ttcttacaat tgcgtgatgg aacagccttc tttcaaggtg
    92461 tggcttttaa accaaacttt gtcgaaaaat ttggtgaaga agtgggactt gagaagtttg
    92521 atgttatcaa acgcttgagc caagaaacgt ctgtttatgt gacaggtatt gtcaaagagg
    92581 acgaacgttc taaatttggc tatgagttgg acatcacaga catcgaagtg atcggtgaat
    92641 ctcaagacta cccaatcaca ccaaaagaac acggaacaga ctttttgatg gataaccgtc
    92701 acttgtggct acgctctcgt aagcaagtag ctgtgttgca aatccgtaac gctattatct
    92761 atgcaactta tgagttcttt gacaagaacg gttttatgaa gtttgacagc ccaattcttt
    92821 caggaaatgc ggcagaagat tctacagaac tctttgaaac tgactacttc ggaacgccag
    92881 cctacttgag ccaatcaggt caactttacc tagaagcagg ggctatggct cttggtcgtg
    92941 tctttgactt tggtccagtt ttccgtgctg aaaaatcaaa aacacgccgt cacttgactg
    93001 agttctggat gatggatgct gagtactcat acttgacaca tgatgagtcg cttgacttgc
    93061 aagaagctta tgtgaaagct cttctacaag gtgttcttga ccgcgcgcct caagccttgg
    93121 aaaccttgga acgtgataca gaactcttga aacgctacat tgcagagcca ttcaaacgta
    93181 tcacttacga tcaagccatt gacctcttgc aagagcatga aaatgatgaa gatgctgact
    93241 acgagcatct tgagcatggt gatgactttg ggtcaccaca cgaaacttgg atttcaaacc
    93301 actttggtgt gccaacattt gtcatgaact atccagcagc catcaaggcc ttctacatga
    93361 aaccagttcc tggaaatcca gagcgcgtgc tttgtgcaga cttgcttgct ccagaaggct
    93421 atggagaaat tatcggtggg tctatgcgtg aggaagatta cgatgccctt gtcgctaaga
    93481 tggatgaact tggcatggat cgtacagaat atgaattcta ccttgacctt cgtaaatacg
    93541 gtacagttcc acacggagga tttggtatcg gtatcgaacg tatggtaacc ttcgcagcag
    93601 gaacaaaaca tatccgtgaa gctattccat tcccacgtat gttgcaccgt atcaaaccat
    93661 aagaacagga aaacgcccat gtggcgtttt ttcgaattct agtgttttta cttgcgtaaa
    93721 aaaatttttt ctagtataat agtttattgt gagcgaacct cacttacccc ttgcaaagtc
    93781 ttggggtcat tagaccaaaa ggaggaacat atcaatggct aaatacgaaa ttctttatat
    93841 cattcgtcca aacattgaag aagaagctaa aaacgctttg gtagcacgtt ttgactctat
    93901 tttgactgac aacggtgcaa ctgttgttga atcaaaaact tgggaaaaac gtcgtcttgc
    93961 atacgaaatc caagatttcc gtgaaggact ttaccacatc gttaacgttg aagcaaatga
    94021 cgatgcagct cttaaagagt ttgaccgtct ttcaaaaatc aacgctgaca ttcttcgtca
    94081 catgatcgtc aaaattgacg cgtaagaagg taaactatga ttaacaatgt tgtacttgta
    94141 gggcgtatga cacgtgacgc tgagttgcgt tataccccat caaatgtagc agttgcgact
    94201 tttactcttg cagtaaaccg tacatttaag agtcaaaatg gtgaacgtga ggctgatttt
    94261 atcaatgtcg ttatgtggcg ccaacaggct gaaaatcttg ctaactgggc taaaaaaggc
    94321 tcacttatcg gggtgacagg tcgtatccag actcgtagtt acgataacca gcaaggacaa
    94381 cgtgtctacg tgacagaggt cgtggctgag aatttccaaa tgttggaaag ccgtagtgtg
    94441 cgtgagggcc acacaggtgg agcttactct gcaccaactg caaactattc agcacctaca
    94501 aattcagtac cagacttttc acgtaatgaa aatccatttg gagcaacaaa cccattggat
    94561 atttcagatg atgatttacc attctaatgg acaactaaac ttataaagga gaaaaaacat
    94621 ggctcaacaa cgtcgtggcg gattcaaacg ccgtaaaaaa gttgattaca tcgcagcaaa
    94681 caaaattgaa tatgttgatt acaaagatac tgagcttctt agccgtttcg tttcagaacg
    94741 tgggaaaatc cttcctcgtc gtgtaacagg aacttcagct aaaaaccaac gtaaagtaac
    94801 aacagctatc aaacgcgctc gcgtaatggc tttgatgcct ttcgtaaacg aagattaaag
    94861 aaaagacccg gttgggtctc tttttcatga gcttgaaaac aagaaagcga attaagaccc
    94921 caacgggtct tttttcacaa gctttgaaat gagagagcga gttaggctca gtggctccct
    94981 ttttacgagt ttgaaaacaa gagaacacat taaaagcacg atggagcttt ttcataaata
    95041 tgtctttttt ctcatccaag aaattaaaat aaaaatgata aactttttga aaatagggga
    95101 tttgcctact ttatgatata atggaaagag ttagattgaa agaggtagtg agatggacgc
    95161 gaaattaaga tacaaggcaa agaagatcaa gattgtcttt tttgatattg atgatacatt
    95221 gcggaattca aagacagggt ttattccaac tacaattccc actgttttta aacagttgcg
    95281 tgaaaaagga attttaacag gaatcgcctc tggacgtggc atttttggtg ttgttccaga
    95341 gattcgtgat ctcaagcctg acttttttgt aactttgaat ggagcttata tcgaagataa
    95401 aaaaggtcag gtcatttatc agcatcagat tgaaaagtca gatgttgagg agtatatctc
    95461 ttgggctaag caagaaggaa ttgaatatgg cttggttggg agtcatgatg ccaagttgtc
    95521 gactcgcacc gatatgatga gtgaagctat caatccaatt tatcccgact tagatgtaga
    95581 tcccgatttc catgaaaaag aagatatcta tcagatgtgg acttttgaag ataagggaga
    95641 tgacttgcac ttgcctgaca gtctctcaga caaacttcgc atggttcgtt ggcatcaaca
    95701 ttcgtctgat attgtgccga tttcaggctc caaagcgacg ggggtggaaa aggttgtgga
    95761 acaccttggc ttgaaaccag agaaggtcat ggtttttgga gatggtctca acgacttgga
    95821 actctttgat tatgctggaa tcagcgttgc catgggaatt tctcatgata aaatcaaaga
    95881 aaaagcagat tatattacaa aaacattaga agaagatggc atttttgatg ccttagaagt
    95941 atttggtatg gtagaaaaag aattgcattt tccacaagta gacattgaaa cagtagaagg
    96001 tcctcttgcg actattaaga ccaatcacgg agacttacgt atcaagcttt tccctgaaca
    96061 tgctcctaaa acagtggcta actttgtatc tctttcaaaa gatggctact atgatggtgt
    96121 cattttccac cgtattatca aggactttat gatccaaggt ggagacccaa ctggaactgg
    96181 tatgggtggc gagtcaatct acggcgaatc ttttgaggat gaattctcag aagagcttta
    96241 caatatccgt ggtgctcttt ccatggcaaa tgctggtcca aataccaacg gcagccagtt
    96301 ctttatcgtg caaaaccaac acctacctta ttcgaagaaa gaaattactc gtggtggttg
    96361 gccagaaccg attgcagaaa tctatgccaa tcaaggtggg acacctcacc tagaccgccg
    96421 tcacacggtt tttggtcagt tagctgatga agcatcttac gctgtcttgg atgccattgc
    96481 tgctgttgag acaggagcta tggacaagcc agttgaagat gttgtaattg aaactattga
    96541 aatcgaggac taagatgaaa atcggtgata agctaaaggg gcgtattaca gggattcagc
    96601 cctacggtgc ctttgttgag ttagagacgg gtgatacggg gctgattcac atttcagaaa
    96661 ttcggacagg atttattgaa aatattcatg aaaccttgaa agtcgatgaa gaggttcaag
    96721 ttcaggtagt ggatttagat gaatttacgg ggaaagccag tctttctatc cgcactttgg
    96781 aggaagaaaa gtaccagttt cctagacgga gacgcttttc aagcgaccgc tttaactacg
    96841 gttttgctcc ctttcgacga atgctaccaa tctggactgg agaagccctg caccatttaa
    96901 aaaagaagaa gtagtttaga gttttatatt ttttgtaatg ttaatatgaa tttgctataa
    96961 taggaccatg gaagaagaac aattattaaa atcaggagag cgcattaacc agctcttttc
    97021 gacagatatc aaaatcattc aaaatagaga ggtttttagc tattcggtgg atagtgttct
    97081 cttatcacga tttccacgtt ttcctaagaa ggggttgatt gtggatttct gtgctgggaa
    97141 tggagcagtg gggctttttg ctagcactcg tactcaagca cagatattgt ctgttgagat
    97201 tcaggagcgt ttggcggata tggctgaacg ctctgtccgt ttgaatggat tagaggagca
    97261 aatgcaggtc atctgcgatg atttgaaaaa tatgcctgct cacattcagg ggagtaaggt
    97321 ggatatgatt ttgtgtaatc caccctattt caaggtgaat ccttattcta atctgaacga
    97381 gagtgaacat tatctcttgg ctcgacacga aatcacgact aatttggaag aaatctgtcg
    97441 tagtgcccag agtattctca agtctaatgg gcgtttggcc atggttcatc gtcctgatcg
    97501 acttctggat attttggata cgttaaaacg acataatcta gcccctaagc gcctgcagtt
    97561 tgtttatcca aaaagagaaa aggaagccaa tatgcttttg attgaggcga tcaaggatgg
    97621 ctcaacaagt ggctttaagg tcttacctcc tttgattgtc cacaatgatg atggctctta
    97681 tacgcccgaa atcgaagaga tttattatgg atcataaggc ttatatgtac gttctggagt
    97741 gtcgtgatgg atcctactat ataggctata cgactgatat gagaagacgc ctcgctatcc
    97801 acaatagtgg gaagggagcc aaatatacac gagcacgctt gccagtcaaa cttatctatg
    97861 ctcaaggttt tgccagtaag gaagaagcca tgtcggctga agctcttctc aagcgtaaga
    97921 agaggccaca gaaggaagaa tttttatctg aaaatcaaga tagaaattta ctcagttatt
    97981 ttgaagaatc gtggggagtc ctttgactcc tcttaccttt gtcaaaaagc gaaaaaaatg
    98041 ctacaataaa gaaaataaac aaaatgaggt attatcatgt ccaagattct agtatttggt
    98101 caccaaaatc cagactcaga tgccatcgga tcatctgtag cttttgccta ccttgcaaaa
    98161 gaagcttacg gtttggatac ggaagctgtt gcccttggaa ctccaaatga agaaacagcc
    98221 tttgtcttga actattttgg tgtggaagca ccacgtgtta tcacttctgc caaagcagag
    98281 ggggcagagc aagttatctt gactgaccac aatgaattcc aacaatctgt atcagatatc
    98341 gctgaagtag aagtttacgg tgttgtagac caccaccgtg tggctaactt tgaaactgca
    98401 agcccacttt acatgcgttt ggagccagtt ggatcagcgt cttcaatcgt ttaccgtatg
    98461 ttcaaagaac atggtgtagc tgtgcctaaa gagattgcag gtttgatgct ttcaggtttg
    98521 atttcagata cccttctttt gaaatcacca acaacacacc caacagataa aatcattgct
    98581 cctgaattgg ctgaattggc tggtgtgaac ttggaagaat atggtttggc aatgttgaaa
    98641 gctggtacca acttggctag caaatctgct gaagaattga ttgatatcga tgctaagact
    98701 tttgaactca acggaaataa tgtccgtgtt gcccaagtga acacagttga catcgctgaa
    98761 gttttggaac gccaagcaga aattgaagct gcaatgcaag ctgccaacga atcaaacggc
    98821 tactctgact ttgtcttgat gattacagat atcgtcaact caaactcaga aatcttggct
    98881 cttggtgcca atatggacaa ggtcgaagcg gctttcaact tcaaacttga aaacaatcat
    98941 gccttccttg ctggtgccgt ttcacgtaag aaacaagtgg tacctcaatt gactgaaagc
    99001 tttaatgcgt aagattttgg gtgtcagctc aaaatcggaa agtctagttt gccttatatc
    99061 gaaaggagtt tcggctcctt ttttctagga gtgaagtatg ttagaaaatg gcgatttgat
    99121 ttttgtgaga gatgggtcag acatgggaca ggccatccag acttccacag gtaactatag
    99181 ccatgttgcc atttatttgg atgggatgat ttatcatgct agtggacagg ctggtgttgt
    99241 ctgtcaagaa ccggcagact tctttgagtc caatcattta tacgacctct atgtttaccc
    99301 agaaatggat atccagtcgg tgaaggaaag agcttgcaaa catcttggag caccctacaa
    99361 tgcttctttc tatccagatg cacctggttt ctactgctcc cagtatatag cagaaatcct
    99421 acctattttt gaaactattc ctatgaaatt tggagatggg gagcaggaga ttagtgattt
    99481 ttggagggag tattacatag aactaggtct gcctgttcct ctgaaccaag ctggtaccaa
    99541 tcctagtcag ttggcagcat cgcctctgtt acaatgtaaa gaaaggaatc ttcatgattc
    99601 agatttttaa tccatctcgt ttgacgagac agccattttt ggagaattga tccgctatct
    99661 ggaccagtat gaggatgtga ttctacggga aattaaggct caatttccag atgttgcagt
    99721 tgataaactc atggaagagt atataaaggc aggcttgatt ctacgtgaaa ataagcgcta
    99781 ttacctcaat tttcctacgc ttgaatcact tgatagtctt gaactggatc aagagatttt
    99841 tgtcagagaa gctagtccgg tctatcaagc cttgttggag cagagttttg agacggaatt
    99901 gcgcaatcaa atcaatgcag ctattttagt tgaaaagacg gactttgcgc gcattaaaat
    99961 gactctgtcc aattattttt acaaggtcaa acagcagtat cctttgacag aaaaacagca
   100021 ggagctctat gacattttag gagatgttaa tcctgagtat gcactcaagt atatgacggc
   100081 ttttttgttg aaatttctca aaaaagacca gcttatgcag aaatgccgtg atatctttgt
   100141 ggacagtttg gttgtcttag gctatattgt gcaaaatgaa gatggaaagt atgagttggc
   100201 tatcgatttt gataaggaga gattaacttt ctacttagcg tgatttcttg tttctgagta
   100261 cattgtttga ctttccttag tattcggtat aaactatatg taaccggtaa cacatatcgg
   100321 aataaactaa aggagacaat catatgtcac ttgaaaacaa attggaacaa gcaacaggcg
   100381 ctgtcaaaga aggttttggt aaagttactg gagacagcaa gacagaactt gaaggagctg
   100441 ttgaaaaaac agttgctaag gcaaaagacg ttgtagaaga cgcaaaaggt gctgtagaag
   100501 gtgccgttga aggtttgaaa aacgttttta ctaaagaata ggaaaaaatc aagggtttca
   100561 ttttcccttg attttttcta ttcttataaa taattttctg cgacggctgt atctcctggg
   100621 taggattctt tcttgccctg gatgatttgg taacaatcgg ctcccttacc cgcaataata
   100681 actgcatcta attcgtgatt tgtgatagcc attgccgcct tgatggcttc ttggcgatcc
   100741 gcaatcttct caacaggatg attgatgtag ctactaattt catctgcaat ggccattggg
   100801 tcttcatagt tagggtcatc agcagtcaga aagacttgaa tctcagggtg ttgattgagg
   100861 aggaggccaa agtccttacg acgactttct cccttgtttc ctgttgatcc cagaaccaga
   100921 gcaatctttc cggtttgatg agtttcaacc acattgatga gttttttcag actatcccca
   100981 ttgtgggcat agtcgatgaa gaccttggct ccatttttct gagtgaggac ttccatacga
   101041 ccaggaacgc gggttgcagc gatgcctttt ttgatgtcct caagacttgc tccgagacgg
   101101 agacaagcaa gtccagcagc aactgcattt tcttggttga agttgccaat gagttggata
   101161 tcataatctc cagcgagttt acccgtagct gaaaagctaa aggctttgga attctcgatt
   101221 tggttatcaa attggctacc atagaaatca tggtcttgat cttcaacctg ttctttcaag
   101281 actgagaagt ggtccatgtc actgttaatg atgactgctc ggctattttc catcaagaga
   101341 cgcttgtggt agaaatagtc ttcaaagcta gggtgttcaa tcgggccgat atggtctggg
   101401 ctgatattga ggaaaactcc cacatcaaag gttagaccat agacacgtct gaccagatag
   101461 gattgactgg agacttccat gatgaggtgg gtacggtcat tttgcacagc ctgattcatc
   101521 atgtcaaaga ggtcaatact ctcaggggtt gtcaacgctg acttaaagaa agtctcgcca
   101581 tcaagagttg tgttcatggt cgacaacata gcaggtcgat gcccttgaga taagatgtta
   101641 taggcgaaat aggctgctgt tgtcttaccc ttagtaccag taaaggcaag gagtttgagt
   101701 ttttcctgtg gattaccata gaactccatg gcaatcaaac tcatggcttt ctttatatcg
   101761 ttcacaatga tgacagggat accgacttcg tagtcctttt cagctacata ccaagctaag
   101821 ccttgtgtta tagcagaaag aaggtattct tttttaaagg cagcgccttt tgcaaaaaaa
   101881 agagtgtctt ctgttacttt tcggctatcg tagctgatgc tatcaaaaac aactttgctg
   101941 tagttgtagt ggtaatgacc ttggtcaata atttcgcgaa aaaggccatc tttctttaaa
   102001 atatctaata cagtttcaat ttttatcata ctttctattg taaaccgaaa gtcgcaaatt
   102061 tacaagtaac aaggaaaagt ttataatgga agataaggag tttttcctag ttatcaaaat
   102121 tgaatgagga atctatgtcg cacgaaaaca atcaccagca ggcccagatg ttacggggga
   102181 ctgcttggct aacggctagt aactttatca gtcgcctact cggggctgtt tacattatcc
   102241 cttggtacat ctggatgggg gcttatgcag ctaaggcaaa tggtctcttt accatgggtt
   102301 acaatatcta tgcttggttc ttgttggttt caacagcggg gattccagtt gcggtggcca
   102361 agcaagttgc caagtataat accatgcgag aagaagagga tagctttgcc ctgattcgga
   102421 gcttcttagg ctttatgaca ggactaggcc tggtttttgc tttagtcttg tatgtctttg
   102481 ctccttggct agcagacttg tctggcgtgg gcaaagactt gatcccaatc atgcaaagct
   102541 tggcttgggg agtcttgatt ttcccgtcta tgagtgttat ccgaggattt ttccaaggga
   102601 tgaataacct caaaccttat gccatgagcc aaattgctga gcaggtcatt cgtgttatct
   102661 ggatgctcct agcaaccttt atcattatga agctcggttc aggagattat ctagcagccg
   102721 ttacccaatc aacctttgct gcctttgtcg gtatggtagc cagttttgca gtcttgattt
   102781 atttccttgc ccaagaaggt tcactcaaaa gagtctttga aacaggagat aagattaaca
   102841 gtaagcgtct cttggttgat accattaagg aagccattcc ttttatcctg acagggtctg
   102901 ccatccagct cttccagatt ttggatcagc tgacctttat caatagtatg agctggttta
   102961 ccaactacag caatgaggac ttggttgtca tgttttctta tttctcagcc aatcctaata
   103021 aaatcacgat gattttgatt tctgtagggg tttcgattgg gagtgttggt ttgccacttt
   103081 tgacggaaaa ctatgtcaag ggggacttga aagcagcttc tcgtctggtt caggacagtc
   103141 tcaccctact ctttatgttc ttgctaccag caacggttgg agtggttatg gtaggagaac
   103201 ctctatatac agtcttctat ggtaagccag atagtttggc tctgggctta tttgtctttg
   103261 cagttttgca gtctattatt ttaggcttgt acatggtctt gtctccaatg cttcaggcca
   103321 tgttccgcaa ccgcaaggcc gttctctatt ttatctatgg ttctattgcc aagctagtct
   103381 tgcaactacc taccatcgcc ctcttccaca gttatggtcc tttgatttca acaaccattg
   103441 ctctcatcat tcctaacgtc ttgatgtatc gggatatttg taaagtaact ggtgtcaagc
   103501 gcaaggtgat tttgaagcga accattttaa tcagtttgct gaccctagtc atgtttctgt
   103561 taataggaac catccagtgg ctgttaggat ttttcttcca accaagtgga cgtttgtgga
   103621 gcttctttta tgtagctctt gtcggtgcca tggggggtgg actttatatg gttatgagtc
   103681 tgcgtaccta tttattagat aaggtaatag gaaaagccca agcagatcgc ctgcgagcaa
   103741 aatttaagct ttcgtaaggt agcatttata aataaaagga ataagttgaa caatctttta
   103801 ggagaacttg aaacttattc cttttttagc gtcaaaatag ctaaaattat ctttcaaaaa
   103861 tagaaaatga ggtttttttg attttttgga aaaaacaatt gactaaacaa accaagagtt
   103921 gtataataaa acaaatattt aaagcaggag gttctggaaa tgaaaaagtc taagagcaaa
   103981 tatctaacct tggcaggtct tgtcctgggt acaggagttt tattgagcgc gtgtggaaat
   104041 tctagcactg catcaaaaac ctataactat gtttattcaa gtgatccatc tagtttgaac
   104101 tatctagcag aaaaccgcgc agcaacatcc gatattgttg caaatttggt agacgggtta
   104161 ttagaaaatg accaatatgg gaatattatt ccatcattag cagaggattg gactgtttct
   104221 caggacggtt tgacctatac ctacaaactt cgtaaggatg ccaagtggtt tacttctgag
   104281 ggagaagaat atgcgcctgt aactgcccag gattttgtga caggtttgca atatgcagct
   104341 gataaaaaat cagaagcttt gtatctagtg caggactctg ttgctggttt ggatgactat
   104401 atcactggta aaacaagcga cttttcaact gtcggtgtca aggcacttga tgaccaaacg
   104461 gttcaatata ctttggttaa accagaactt tactggaatt caaaaacact tgcaacgata
   104521 ctttttcctg ttaatgcaga tttcctgaaa tcaaaagggg atgattttgg gaaggcggat
   104581 ccatctagta ttttgtacaa tggacctttc ttgatgaaag cacttgtctc aaaatctgct
   104641 attgaatata agaaaaaccc taattactgg gatgctaaga atgtctttgt agacgatgtg
   104701 aaattgacct actatgatgg tagcgaccaa gaatcactgg aacgtaattt tacagctggt
   104761 gcttatacta cggctcgtct ttttcctaac agctccagct atgaagggat taaagaaaaa
   104821 tacaaaaaca atatcatcta tagtatgcaa aattcaactt catatttctt taattttaac
   104881 ctagatagga agtcttacaa ttatacttct aaaacaagtg acattgaaaa gaaatcgacc
   104941 caggaagcag ttctcaataa aaacttccgt caggctatca attttgcttt tgacagaaca
   105001 tcttatgggg ctcagtctga agggaaagaa ggtgcaacaa agattttgcg taacctagtg
   105061 gttcctccaa actttgtcag tatcaaggga aaagactttg gtgaagttgt agcctctaag
   105121 atggtcaact atggtaagga atggcaaggt atcaactttg cggatggtca agacccttac
   105181 tacaatcctg agaaagccaa ggctaagttt gcggaagcta agaaagaact cgaagcaaag
   105241 ggtgttcaat tcccaatcca cttggataag actgtggaag taacagataa agtaggcata
   105301 caaggagtta gttctatcaa acaatcaatt gaatctgttt taggttctga taatgtagtg
   105361 attgacattc agcaattaac atcagatgag tttgacagtt caggctactt tgctcaaaca
   105421 gctgctcaga aagactatga tttatatcgt ggcggttggg gacctgatta tcaagacccg
   105481 tcaacctatc tcgatatttt taatactaat agtggaggag ttctacaaaa tcttggacta
   105541 gagcctggag aagccaatga caaggctaag gcagttggac tggatgtcta tactcaaatg
   105601 ttggaagaag ctaataaaga gcaagatcca gccaaacgtt atgagaaata tgctgatatt
   105661 caagcttggt tgattgatag ttctttagtt cttccaagtg tttcgcgtgg gggaacacca
   105721 tcattgagaa gaaccgtacc atttgctgct gcctatggtt taaccggtac aaaaggggtt
   105781 gaatcatata aatacctcaa agtacaagat aagattgtca caacagacga atatgcaaaa
   105841 gccagagaaa aatggttgaa agaaaaagaa gaatccaata aaaaagccca agaagaattg
   105901 gcaaaacatg tcaaataaaa tctaattgta gataagtttg tgtaagaagt ctttgtgctt
   105961 aaaaacgcat aatatcaggt atataaaatc ctagatgtta tgcgttttgt tataggaaga
   106021 tttattagat tttatcctca aattgagtta ttcccgactt tatccgttga aatattataa
   106081 ggagtattta tgaaattaaa attattaaga gtagatacta aggtgattat ggggagtttc
   106141 ttacttgttc tgtctagtct acttgctttg ttgcttcccc ttatcttaaa gggtttaata
   106201 gatgggagtt ctattgaaaa tataggttcc aaagtatttc aatcgttttt gatttttatt
   106261 ggtcaagcct tgttttcttc tattggttac tatctgttta gtcaatcggg tgaaaaaaag
   106321 atagcaaaaa tcaggaaaaa agtgatagag gggttgattt atgcagagaa atccttcttt
   106381 gataagagcc aaagtgggga gttgacttct gccattgtca atgacatgag tgtcattcgt
   106441 gagtttttaa ttacgacttt cccaaatatt attctgagtt tagttatggt acttggttcc
   106501 attgtagtct tatttagtct tgattggaat ctttctctac ttttattcat cactcttcct
   106561 tgtatgatgt ttattatctt gcccctttcc aatatcagtg aaaagtatag tcgtcgttta
   106621 caggaggaaa tttaacaggg caattgactg aaaagattca agaacatgaa ttaattaaga
   106681 ctaaccaagc agagaaaagt gtacaggatg ttttggataa ttgtattgaa agggtacaaa
   106741 acaattcact gaaatcagat agggttactt cttttgagac ctcgtttgct ctcttattta
   106801 tctttgcgac tatagttgtg atgctaacct atgggggtta tcgggtcagc gcaggatata
   106861 tatctgtggg aaccttggtt tcgtttttga tttacctctt tcaattactt aatcctatta
   106921 gtaatatagc taattttgta actgtttatt ctaggagcaa gggatcttca gttgcactgg
   106981 ataacttgct tgcagttcct aaagaaaaat ttgagggagg aaaatcggta tcaggacaag
   107041 ggttgaattt taaccatgtc tattttggtt atgatgaaaa tcgacctgtc ttaaaggata
   107101 ttacttgttc aattttcaag gggcaaaaat tgcttttgtt ggaccatctg gatcaggaaa
   107161 atcaacgatt gtgcgtttgt tagagcggtt ttataaaccg ctttcaggag atattctaat
   107221 ggagcaatca agtatatatg attttaactt aaaagaatgg agaagtaaaa tcgcttgggt
   107281 ttcacaaaat aatgcagtct tatctggcag tattcgtgac aatctttgtc tcggtttgaa
   107341 tcgcttagta actgatgatg aattgatgaa agtgctagac ttagtatcac taggtgatga
   107401 gattcgctcc atgaaagagg gactagatac tgaagttggt gaacgcggac gattcttgtc
   107461 aggggggcaa agccaaagac ttcaaatagc tagaacctac ttaaaagatg ctgaaattct
   107521 tatatttgat gaagctactg ctaatcttga tgcggattct gagtatgcga ttatcagtag
   107581 cctctattct gtattaaagg agaagacggt tgtgattata gcgcatagtt tgtcaacggt
   107641 aaaagatgtg gattgtattt tcttcttaga ggaggggaaa atcactggct caggaactca
   107701 taaggaacta ctggaaaatc atgagcgtta tgctcgtttt gtgcaggagc aaatgataga
   107761 gtgaagtgtc ttttgagatt caccatttta tagtctatta aagggagcag gaaaaactcc
   107821 ctttttatat agtttgaaac tataactagc tcttgaaaag aagaaaatga gttgatgaaa
   107881 ataagtggta caatagttac tatagatttg gaggtattgt atgagcaagg aattacacat
   107941 taacacaatt ttggcccagg cgggtattaa gtcagatgaa gcgacaggtg cattggtgac
   108001 accgcttcat ttttcaacga cctatcagca tccagagttt ggtcgatcta ctgggtttga
   108061 ctatacgcgc actaaaaatc caactcgtag taaggctgag gaagtcttgg cggctattga
   108121 gtcagcagac tatgccttag cgactagctc agggatgtca gctattgtac tggcctttag
   108181 cggctttcca gtaggaagta aggtcttggc agtgcgtgat ctttacggcg gttcttttcg
   108241 ctggtttaac caagtggagc aggaaggtcg tttccatttt acctatgcca atacagaaga
   108301 agagttgatt gccgagttag aaaaggatgt ggatgttctc tatatcgaaa ccccaaccaa
   108361 tcccttgatg ttggaatttg atatcgaaaa actagcaaaa ttggctcatg ctaagggtgc
   108421 caaagtggtg gtggacaata ccttctatag ccctatctac caacgtccga ttgaagatgg
   108481 agcagatatc gttctccatt cagcaaccaa gtatctagca ggccacaatg atgtcttggc
   108541 tggagtggtt gtgaccaata gtttagaact atacgagaag cttttttaca atcttaatac
   108601 aacaggggca gtcttgtctc catttgacag ctatcagttg cttcgtggtc tcaagacctt
   108661 gtctcttcgt atggagcgct caacagctaa cgcccaagaa gtggttgcct ttttgaagga
   108721 ttctccagca gttaaggaag ttctctacac tggtcgtgga ggcatgattt cctttaaagt
   108781 agccgatgaa acacgcattc ctcatatttt gaacagtctc aaggtcttct cttttgcgga
   108841 aagtttgggt ggagtggaaa gtcttattac ttatccaacg actcaaactc atgctgatat
   108901 tccagcagag gtacgccatt cttatggttt gacagatgac ctcttgcgtt tgtctattgg
   108961 gattgaggat gctagagatt tgattgcaga tttgcgccaa gccatagaag gataagacaa
   109021 agatgggaaa atatgatttt acaagcctgc ccaaccgttt agggcaccat acctataaat
   109081 ggaaagaaac agaaacggat agtgaagttc taccagcttg gatagcggat atggactttg
   109141 tggtcttgcc tgaaatccgc caagccgtgc aaacttacgc agaccaactg gtttatggtt
   109201 atacctatgc cagtgaagac ttaattaagg aagttcaaaa gtgggaagct acacaatacg
   109261 gttacaactt tgacaaagag gctcttgtct ttatcgaggg tgtggtacca gccatctcaa
   109321 cagctattca aacctttaca aaagaaggcg aggcggtttt aattaacacg cctgtctacc
   109381 caccctttgc tcgcagtgtc aagttgaata atcgtagatt gattactaat tccttagtgg
   109441 aaaaggatgg tctgtttgag attgactttg accaacttga aaaggatttg gtggaagagg
   109501 aggttaaact ctatattctt tgcaaccctc acaatcctgg tggacgtgtt tgggaaaaag
   109561 aagtgttgga gaagattggc caactctgcc aaaaacacgg tgttttgtta gtttcggatg
   109621 agattcacca agatttgacc ctctttggtc acaaacacca gtctttcaat accatcaatc
   109681 ctgccttcaa aaattttgct atcgtcttga gcagtgccac taaaacattt aatattgctg
   109741 gaacaaaaaa ttcctatgca gtcattgaaa atcctaagtt gagactagct ttccagaaac
   109801 gcctgttggc caataatcag catgaaattt caggcttggg ttatttggcg acagaagctg
   109861 cctatcgata cggtaaagat tggctagagg aactcaagca agtctttgaa gaccacatca
   109921 attatgtggt ggatctattt ggaaaagaga ctaaaatcaa ggtcatgaaa ccgcaaggta
   109981 cctacttgat ttggcttgac ttttcagctt atgacctgac tgatgaaaca ttgcaagagt
   110041 tgttgagaaa tgaagccaag gttatcctca accgtggttt ggattttgga gaggaaggaa
   110101 gtctccatgc ccgcatcaat atagctatgc ccaaatctct gttgcaagaa gtctgtcagc
   110161 ggattgtggc tacttttgcc aaacgttaaa aatccagcct tctaggagaa aagtcttcct
   110221 agaaggctat tttcataggc gaaaatatgg tataataaaa agataaggta aaggtgaaaa
   110281 tatggctaaa ttgattccgg ggaaaattcg tatcgaaggt gttgcccttt atgaaactgg
   110341 taaggttgat atcatcaagg aaaagaacaa tcggctctac gctcgcgttg cagaagaaga
   110401 actgcgctat agtttagagg atgatttggt tttttgtgcc tgtgattttt ttcaaaagag
   110461 gggttactgt gtgcatttgg cagcgctaga gcattttctg aaaaatgatg agcgtggtca
   110521 ggaaatcttg tggagtctgg aagaaggtca tgaagaaaaa gaggctgttg aaaccaaggt
   110581 gaccttgggt ggcaagtttt tggatcgaat tttatctcca aaatcagaat gcgcctatga
   110641 gttatcagct gtgggtcagg tggaagcagg aaccaatcat atcttgtgga ctctgagaat
   110701 cggccaaatc aatagccaaa aatactatgt cattcgggat attccacttt ttttaaggat
   110761 tgtcgagcag agaaagtcgt atatgattgg caagatttat gaggagtctc tttcttggga
   110821 agcctttgat gatgccagcc aagaactttt gactttcttg cacggactaa cggaggaagg
   110881 gctggtttca gacctctttt tccaaaacca aggtcggcac ctctttttcc ctctgacctt
   110941 ttttgagcag ggtgtgaatt tactgatggc cttgccccat tttcaatttg accatcaagt
   111001 ggatagctac caaaccctgc tttttcagga tatgcatgct gatgccaatc tatttgcctt
   111061 tacagtaaca gaatactcgg actattttga aatggaaatc agtgagagtc ctagggtcaa
   111121 tgtcttttat cagggagcag tacttttcca taaaggtcag gtttattttt taacagacca
   111181 gcagatgcgt cttctcaagg aaattaaagc gttacctgtg ggtcaacaag gaaagaaata
   111241 cctgcaattt gatagcagtg atcgagacaa attggcctcc tgtctgactc tttttatcca
   111301 gatgggcacc gtttcagctc cagaacgtct acaaatcaaa acttttgcgc cctcttttta
   111361 ctttgacagg gaagaagata atcggattcg tttagaaatt cagtttgatt atggaaatag
   111421 acaggtatct agccgacaag agctagaaga attaccattt tcaagtgacg cggacttaga
   111481 agaaagaatt ttccaagtct gtttggctgc gggctttgaa gccgattttc aatcttggcg
   111541 tcaggcctta aaagcggagt ctgtctatca tttttttcat gatatcattc cagtctttga
   111601 aaaactcggg catgttgacc tatcagataa actagaagag ctttatagcc tagcgagtcc
   111661 tcaggtgcag attgcctcca agggaggtct cttggaaatc cagtttgatt ttcaagatat
   111721 tgcccaggag gaaatcgacc aagccatgca ggccttggtt gccaatcagg atttttatat
   111781 tgattcgtct aatcaagttt actttttcga tgaagaaacc aagaaaattc gccaaaatct
   111841 acaggaactg gggcaatttg aattaaaaga tgggaccttg caggctcgga aatccttggc
   111901 ctacagttta gctcatctct ttgaagggcg agaccgtgtt tctttttcac aagaattcca
   111961 gaatctggcc caggatttga cacatccaga ggactttcct cgacaggcaa ctcaggttca
   112021 ggctgacttg cgagattatc aggaaaaggg aattggctgg ttgcagatgc tccatcatta
   112081 tggttttggt gggattttgg ctgatgatat gggacttggg aaaacccttc agaccattgc
   112141 ttttttgact agtcaagtga caaaagaaag tcgggttttg attctcgctc cgtcaggttt
   112201 gatttacaac tgggcagatg agtttcagaa atttgcccca cagttggatg tggctgttgt
   112261 tcatggtttg aaagcaagtc gtgaggagat tcttgccgag agccatcaaa tctatgtgac
   112321 tagctatgcc accttccgtc aggacagtga gttttatcag gggatggcct ttgacttcct
   112381 tttcttagat gaggctcagg tcatgaaaaa tgcccagacc aagattgccc agaccttgag
   112441 acaatttgtg gtgccgtcgg tctttgcctt gtcaggaact ccgattgaaa accatctggg
   112501 tgagttgtgg tctattttcc aaatcgtcat gcccggactt ttgccaagca agaaagaatt
   112561 tatgaaattg ccagcagagc gagtggctca gtttatcaag cctttcgtga tgcgacgcaa
   112621 gaaagaagaa gttctgactg aattgccaga cttgattgag gtggtttata aaaatgaact
   112681 ggaagaccag caaaaggcta tttaccttgc ccagttacaa cagatgcgag accatctggc
   112741 tcaagtgtca gaacaggaat ttcagcgaag tcgtgtggaa attttatctg gtttgatgcg
   112801 cttgcgtcaa atatgtgaca ctcctgccct gtttatggaa gattatcagg gagccagcgg
   112861 caaactagat agtctccgag atctactggt acaggtggca gacggcggac accgtgtctt
   112921 gattttctct cagttcaagg gaatgttgga aaaaattgaa caagaactgc cagacttggg
   112981 cctgacatcc tttaaaatta cgggtttaac cccagccaag gaaagacaag acatgaccaa
   113041 ggcctttaac caaggagaaa gagatgcctt tctgatttcc ctcaaggctg gtggggtcgg
   113101 tctgaacctg acaggtgcag atacagtgat cttggttgac ctttggtgga atcctgcggt
   113161 ggaagcgcaa gccattggcc gtgcccatcg gatgggtcag gaagaaacgg ttgaggtcta
   113221 tcgcttggtg accaagggaa ccattgaaga aaaaattcag gaactccaag aacaaaagaa
   113281 acatctggtg tcacaagtat tggatggcac agagtcacgt ggtagtctga ccctagcaga
   113341 aattagagaa attttgggaa tttctgaagc cagcacttga aaaatcaaga caatacgcta
   113401 taatgaagtg ttgaaaggaa atagaaaatg aaacaagaac gatttccatt ggtgtcagat
   113461 gacgaggtca tgttgactga aatgccagtc atgaatctct atgatgagtc tgatctgatc
   113521 agtaatatca agggtgagta tcgagataaa aattatttag aatgggctcc tattactgaa
   113581 gaaaaaccag taaaaccgat tgaaaagcaa gtcgaaaaac ctaaaaaggc tcctttaggg
   113641 gttaaaaaag aaggaaagag ctatgcggag gtggcgcgtg aagaagcgcg tgcggacttg
   113701 aaaaagaaac gctctgctaa ctacctaact caggatttca gccttgcgag acgtcattct
   113761 cagcccagtc tagttagaca gggcaatcaa ccgacaactc ctttccaaaa ggaaaatcct
   113821 ggtgaatttg tcaaatatag ccaaaaattg acccagtctc attatatctt ggcggaagaa
   113881 gttcattcta tccctaccaa gaatgaagaa gtgtcagcac ctgctccaaa gaaaaacaat
   113941 tatgattttc taaagaagag ccaaatctac aataaaaaaa gtaaacaaac agaacaagaa
   114001 cgtcgggttg cccaagagtt gaatctgacc agaatgacag aataggggag aaaacatgtc
   114061 aaagacatat cattttatcg gaattaaggg atcagggatg agtgccttgg ccttgatgtt
   114121 gcaccagatg gggcacaagg ttcagggatc agatgttgaa aagtactact ttacccaacg
   114181 cggtcttgag caggcaggaa ttaccattct tccttttgat gaaaagaatc tagacggtga
   114241 tatggaaatt atcgctggaa atgcctttcg tccagataac aacgtcgaaa ttgcctatgc
   114301 ggaccaaaat ggtatcagct acaaacgtta ccatgagttt ctaggtagct ttatgcgtga
   114361 ctttgttagc atgggagtag caggagcaca tggaaaaact tcaacgacag gtatgttgtc
   114421 tcatgtcttg tctcacatta cagataccag cttcttgatt ggagatggga caggtcgtgg
   114481 ttcggctaat gccaaatatt ttgtctttga atctgacgaa tatgagcgtc acttcatgcc
   114541 ttaccaccca gaatactcta ttatcaccaa cattgacttt gaccatccag attatttcac
   114601 aagtctcgag gatgttttca atgcctttaa cgactatgcc aaacaaatta ccaagggtct
   114661 ttttgtctat ggtgaagatg ctgaattgcg taagattacg tctgatgcac caatttatta
   114721 ttatggtttt gaagctgaag gcaatgactt tgtagctagt gatcttcttc gttcaacaac
   114781 tggttcaacc ttcaccgttc atttccgtgg acaaaacttg gggcaattcc acattccaac
   114841 ctttggtcgt cacaatatca tgaatgcgac agccgttatt ggtcttcttt acacagcagg
   114901 atttgatttg aacttggtgc gtgagcactt gaaaacattt gccggtgtta aacgtcgttt
   114961 cactgagaaa attgtcaatg atacagtgat tattgatgac tttgcccatc atccaacaga
   115021 aattattgcg accttggatg cggctcgtca gaaataccca agcaaggaaa ttgtagcagt
   115081 ctttcaaccg cataccttta caagaaccat tgccctgttg gacgactttg cccatgcttt
   115141 aaaccaagca gatgctgttt atctagcgca aatttatggc tcggctcgtg aagtagatca
   115201 tggtgacgtt aaggtagaag acctagccaa taaaatcaac aaaaaacacc aagtgattac
   115261 tgttgaaaat gtttctccac tcctagacca tgacaatgct gtttacgtct ttatgggagc
   115321 aggagacatc caaacctatg aatactcatt tgagcgtctc ttgtctaact tgacaagcaa
   115381 tgttcaatag gatgttccca tggaaattcc aattaagatc attcaggcaa gcaagtttga
   115441 tttgcctgag ataggggcac ttcagacctc gtcttttcca gctgaaaagc agcaactttc
   115501 ccatatttta gaagaaagta tccgtaagtg tgcggatacc tttcttctag ctagggatga
   115561 aaatcaactt ttaggctata ttttatcaag tccccagtca gacaatccgc aatgtctaaa
   115621 agtacattct ttagtcatcg agtctgacca tcagagacag ggcctgggaa cacttcttct
   115681 tgcagccttg aaagaggtgg cagttgagct ggattacaaa gggattcgtt tggagagtcc
   115741 tgatgagctg ctttcctatt ttgaaatgaa cggttttgtt gatgaagaag aaattttgct
   115801 ctatgcaact agccagggct atagtatgat ttggtttaat cccttttatc tggaggaaca
   115861 atgaaaatca gacaagcaag attagaagat ttggatcgga ttgttgaact tgaatttgaa
   115921 aatttttcgg tcgaagaagc cattcctcct tctgtctttg aagcacattt gagagaaatt
   115981 cagacctctt ttctggttgc tgaaaaagaa ggaagaatca tgggttatat cgaaggacca
   116041 gttggcctgc accgccatct gcaagaccag tcttttacag aagaaataaa agactatagt
   116101 catgagcctg gtggttatat ctctgtgacc tgtctgtcta ttgccaagga ggcacaggga
   116161 ctcggactgg gtcagaaatt gctgacagcc ttgaaagaag ttgctcttga agatgagaga
   116221 gatggcatta atctaacctg tcatgactat ctcatcgcct attatgaaaa acatggattt
   116281 gtcaacgaag gccagtccca gtcaaccttt gcaggggaaa catggtatga tatggtctgg
   116341 gaaatgaaaa aataagttag gaaaagtatc atagattgct ttttttggac ttttaagata
   116401 taatattatg gattatcaac aaggaggaaa aacttttgag tgaaaagtca agagaagaag
   116461 agaaattaag ctttaaagag cagattctga gagatttaga aaaagtaaaa ggctatgatg
   116521 aagttctgaa agaagatgag gcagtagttc gcactcctgc aaatgaacct tcagctgaag
   116581 aactcatggc tgattccttg tcaacggtag aggagattat gagaaaagct cctaccgtgc
   116641 ctactcaccc aagtcaaggt gtaccagctt ctccagcaga tgagattcaa agagaaactc
   116701 ctggtgttcc aagtcatcca agtcaagatg taccttcttc tccagcggaa gaaagtggat
   116761 caagaccagg tccaggtcct gttagaccta agaaacttga aagagaatac aatgaaaccc
   116821 caacaagggt agctgtttcc tatacgacgg cagagaaaaa agcagaacaa gcaggtccag
   116881 aaacacctac gcctgctaca gaaacagtgg atatcatcag agatacatca cgtcgtagcc
   116941 gtagagaagg agcaaaaccc gttaagccta agaaagagaa gaagtcacat gtgaaagctt
   117001 ttgtgatttc attccttgta ttccttgcct tgctctcagc aggtggttac tttggttacc
   117061 agtacgtgct agattcctta ttacctatcg atgctaattc taagaaatat gtgacggttg
   117121 gaattccaga aggttcaaac gttcaagaaa tcggtacgac gcttgaaaaa gctggtttgg
   117181 taaagcatgg tctgattttt agtttttatg ccaagtataa aaattatacc gacttgaaag
   117241 caggttacta caatttgcaa aagagtatga gtacagaaga cttactcaaa gagttgcaaa
   117301 aaggtggaac agatgaaccg caagaacctg tacttgcgac tttgacaatt ccagaaggtt
   117361 ataccttgga tcagattgct caaactgtgg gtcaattgca aggtgacttc aaagagtctt
   117421 tgacagcgga ggctttcttg gctaaagttc aagatgagac gtttatcagt caagcagtag
   117481 cgaaatatcc tactttactg gaaagtttgc ctgtaaaaga cagcggtgcg cgttatcgtt
   117541 tggaaggata ccttttccca gctacatact ctatcaagga aagcacaact attgagagct
   117601 tgattgatga gatgttagct gctatggata agaacctatc tccttactat agtactatca
   117661 aatctaaaaa cttgactgtc aatgagttgt tgaccattgc ttccttggtc gaaaaagaag
   117721 gtgccaagac agaagatcgt aagctcattg caggtgtatt ctacaatcgt ttgaatcgtg
   117781 atatgccact tcaaagtaat attgcaatct tgtatgccca aggaaaactg gggcaaaata
   117841 tcagtctagc tgaggatgtt gcgattgata ccaacattga ttcaccttat aatgtttata
   117901 aaaatgtagg tctcatgcct ggtccagtcg atagtccaag tctggatgcg attgagtcaa
   117961 gcatcaatca aactaagagc gataacctct actttgtagc agatgtcaca gaaggcaagg
   118021 tctactatgc taacaatcaa gaagaccacg accgcaatgt cgctgaacat gtcaacagca
   118081 aattaaacta aacaaactaa aattatgtga tacttcacat aattttcttt agaaaatatt
   118141 atcagaagaa agttgagaaa aatggcagaa aaaacatatc ctatgaccct tgaggaaaag
   118201 gaaaaacttg aaaaagaatt agaagaattg aaattggttc gtcgaccaga agtggtagaa
   118261 cgcattaaga ttgcccgttc atacggtgac ctttcagaaa acagtgagta cgaagcagct
   118321 aaggatgaac aagcctttgt cgaaggacaa atctctagct tagaaacaaa aatccgctat
   118381 gctgaaatcg tcaatagcga cgcagttgcc caggacgaag tagcgattgg taaaacagtc
   118441 accatccaag aaattggtga ggacgaagaa gaagtttata ttatcgtagg ttcagctggt
   118501 gcggatgcct ttgcaggtaa ggtttcaaat gaaagcccaa ttgggcaggc cttgattggc
   118561 aagaaaacag gtgatacagc aaccattgaa acgcctgttg gtagctatga tgtaaaaatc
   118621 ttgaaggttg aaaaaacagc ctaaaaacag aaaaaggagt ggggaggcga tgtgcttcac
   118681 tcactccttt ttccattttg ctactcttcg aaaatctctt caaaccacgt cagcgtcgcc
   118741 ttgccgtatg tatggttact gacttcgtca gtttcatcta caacctcaaa acagtgtttt
   118801 gagcaacctg cggct
//
LOCUS       DBEJKC010000002        69025 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.002, whole genome shotgun sequence.
ACCESSION   DBEJKC010000002 DBEJKC010000000
VERSION     DBEJKC010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 69025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69025
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.002"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            2..667
                     /locus_tag="ACL3G6_000121"
     CDS             2..667
                     /locus_tag="ACL3G6_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001840203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544724.1"
                     /translation="MYLGLIISFIPPILLTFFILKTQGTSLGIKHISNFYAMLGMLMA
                     VIHANRIISRDFSHNTISLFYNQQKNRMIYLLSNFLYAISVSIIYALNGIVLLVIVSK
                     LGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYKLKSGLVFGILVALLLFIPNIL
                     NTMMMNTSNDLFIKAIELLPFYSLPVFVTSNTMSISQYLVVITTIILLYFFTLKKSKK
                     YSF"
     gene            1053..1262
                     /locus_tag="ACL3G6_000122"
     CDS             1053..1262
                     /locus_tag="ACL3G6_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0544725.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            1252..1740
                     /locus_tag="ACL3G6_000123"
     CDS             1252..1740
                     /locus_tag="ACL3G6_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6773 family protein"
                     /protein_id="HGR0544726.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            1856..3316
                     /locus_tag="ACL3G6_000124"
     CDS             1856..3316
                     /locus_tag="ACL3G6_000124"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HGR0544727.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISYMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            3313..4137
                     /gene="nadE"
                     /locus_tag="ACL3G6_000125"
     CDS             3313..4137
                     /gene="nadE"
                     /locus_tag="ACL3G6_000125"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HGR0544728.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            4434..4985
                     /locus_tag="ACL3G6_000126"
     CDS             4434..4985
                     /locus_tag="ACL3G6_000126"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0544729.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            6029..6250
                     /locus_tag="ACL3G6_000127"
     CDS             6029..6250
                     /locus_tag="ACL3G6_000127"
                     /inference="COORDINATES: protein motif:HMM:NF019142.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGR0544730.1"
                     /translation="MKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVT
                     TITYNVDGKSGQVTESTLSQKKRLSNKSC"
     gene            6446..6835
                     /locus_tag="ACL3G6_000128"
     CDS             6446..6835
                     /locus_tag="ACL3G6_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGR0544731.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(7496..8524)
                     /gene="queA"
                     /locus_tag="ACL3G6_000129"
     CDS             complement(7496..8524)
                     /gene="queA"
                     /locus_tag="ACL3G6_000129"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HGR0544732.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            8675..9382
                     /locus_tag="ACL3G6_000130"
     CDS             8675..9382
                     /locus_tag="ACL3G6_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HGR0544733.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            9460..9969
                     /locus_tag="ACL3G6_000131"
     CDS             9460..9969
                     /locus_tag="ACL3G6_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544734.1"
                     /translation="MNKEEFLKIKEAYKSARTEERKSIIGFITKKKDKEGNFLFTKSK
                     DKPYTTRNQYSGGGGNKKYTSGSRLSRPYDLSNHMWIDLSYKGNDILISLQSFDIDPN
                     SKELHVLYDRIGILFEQSKKIPIFKDCYTITKVSDAFLKMETTNWELPLSKADMEEMV
                     NYIINHYEE"
     gene            10049..10225
                     /gene="rpsU"
                     /locus_tag="ACL3G6_000132"
     CDS             10049..10225
                     /gene="rpsU"
                     /locus_tag="ACL3G6_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HGR0544735.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            10355..11290
                     /gene="hprK"
                     /locus_tag="ACL3G6_000133"
     CDS             10355..11290
                     /gene="hprK"
                     /locus_tag="ACL3G6_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HGR0544736.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            11283..12071
                     /gene="lgt"
                     /locus_tag="ACL3G6_000134"
     CDS             11283..12071
                     /gene="lgt"
                     /locus_tag="ACL3G6_000134"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HGR0544737.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            12072..12498
                     /locus_tag="ACL3G6_000135"
                     /pseudo
     CDS             12072..12498
                     /locus_tag="ACL3G6_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
     gene            12471..12860
                     /locus_tag="ACL3G6_000136"
     CDS             12471..12860
                     /locus_tag="ACL3G6_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGR0544738.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIHITEE"
     gene            12944..14074
                     /gene="hemW"
                     /locus_tag="ACL3G6_000137"
     CDS             12944..14074
                     /gene="hemW"
                     /locus_tag="ACL3G6_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HGR0544739.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            14079..14816
                     /locus_tag="ACL3G6_000138"
     CDS             14079..14816
                     /locus_tag="ACL3G6_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HGR0544740.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            14827..15600
                     /locus_tag="ACL3G6_000139"
     CDS             14827..15600
                     /locus_tag="ACL3G6_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HGR0544741.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            15590..16207
                     /locus_tag="ACL3G6_000140"
     CDS             15590..16207
                     /locus_tag="ACL3G6_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HGR0544742.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            16417..16818
                     /locus_tag="ACL3G6_000141"
     CDS             16417..16818
                     /locus_tag="ACL3G6_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGR0544743.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            16818..17096
                     /locus_tag="ACL3G6_000142"
     CDS             16818..17096
                     /locus_tag="ACL3G6_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HGR0544744.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            17086..17859
                     /locus_tag="ACL3G6_000143"
     CDS             17086..17859
                     /locus_tag="ACL3G6_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HGR0544745.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSSTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRSVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            17860..19164
                     /locus_tag="ACL3G6_000144"
     CDS             17860..19164
                     /locus_tag="ACL3G6_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HGR0544746.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            19738..20616
                     /gene="pstS"
                     /locus_tag="ACL3G6_000145"
     CDS             19738..20616
                     /gene="pstS"
                     /locus_tag="ACL3G6_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HGR0544747.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            20616..21533
                     /gene="pstC"
                     /locus_tag="ACL3G6_000146"
     CDS             20616..21533
                     /gene="pstC"
                     /locus_tag="ACL3G6_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGR0544748.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            21523..22407
                     /gene="pstA"
                     /locus_tag="ACL3G6_000147"
     CDS             21523..22407
                     /gene="pstA"
                     /locus_tag="ACL3G6_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGR0544749.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            22418..23221
                     /gene="pstB"
                     /locus_tag="ACL3G6_000148"
     CDS             22418..23221
                     /gene="pstB"
                     /locus_tag="ACL3G6_000148"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR0544750.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            23234..23992
                     /gene="pstB"
                     /locus_tag="ACL3G6_000149"
     CDS             23234..23992
                     /gene="pstB"
                     /locus_tag="ACL3G6_000149"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR0544751.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            24004..24657
                     /gene="phoU"
                     /locus_tag="ACL3G6_000150"
     CDS             24004..24657
                     /gene="phoU"
                     /locus_tag="ACL3G6_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGR0544752.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            24814..25629
                     /locus_tag="ACL3G6_000151"
     CDS             24814..25629
                     /locus_tag="ACL3G6_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0544753.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKNEGTYQSYLEKAASLTEVEE"
     gene            complement(25649..26920)
                     /locus_tag="ACL3G6_000152"
     CDS             complement(25649..26920)
                     /locus_tag="ACL3G6_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGR0544754.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            27062..27793
                     /gene="budA"
                     /locus_tag="ACL3G6_000153"
     CDS             27062..27793
                     /gene="budA"
                     /locus_tag="ACL3G6_000153"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HGR0544755.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            27803..28555
                     /locus_tag="ACL3G6_000154"
     CDS             27803..28555
                     /locus_tag="ACL3G6_000154"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family glutamic-type intramembrane
                     protease"
                     /protein_id="HGR0544756.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            28667..29617
                     /gene="murB"
                     /locus_tag="ACL3G6_000155"
     CDS             28667..29617
                     /gene="murB"
                     /locus_tag="ACL3G6_000155"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HGR0544757.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            29676..30833
                     /locus_tag="ACL3G6_000156"
     CDS             29676..30833
                     /locus_tag="ACL3G6_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0544758.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            30814..31620
                     /locus_tag="ACL3G6_000157"
     CDS             30814..31620
                     /locus_tag="ACL3G6_000157"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0544759.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            31617..32390
                     /locus_tag="ACL3G6_000158"
     CDS             31617..32390
                     /locus_tag="ACL3G6_000158"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0544760.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            32387..33457
                     /locus_tag="ACL3G6_000159"
     CDS             32387..33457
                     /locus_tag="ACL3G6_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0544761.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYEAFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKLEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            33718..33957
                     /locus_tag="ACL3G6_000160"
     CDS             33718..33957
                     /locus_tag="ACL3G6_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544762.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLNDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            34232..34717
                     /locus_tag="ACL3G6_000161"
     CDS             34232..34717
                     /locus_tag="ACL3G6_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HGR0544763.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            34739..37357
                     /gene="alaS"
                     /locus_tag="ACL3G6_000162"
     CDS             34739..37357
                     /gene="alaS"
                     /locus_tag="ACL3G6_000162"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HGR0544764.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVDNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAIAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(37447..38901)
                     /locus_tag="ACL3G6_000163"
     CDS             complement(37447..38901)
                     /locus_tag="ACL3G6_000163"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HGR0544765.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANKELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            39080..39829
                     /locus_tag="ACL3G6_000164"
     CDS             39080..39829
                     /locus_tag="ACL3G6_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0544766.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            39810..41444
                     /locus_tag="ACL3G6_000165"
     CDS             39810..41444
                     /locus_tag="ACL3G6_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544767.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEMPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPVLTLLGLSLYLGLPILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            42129..43292
                     /locus_tag="ACL3G6_000166"
     CDS             42129..43292
                     /locus_tag="ACL3G6_000166"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HGR0544768.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            43289..43966
                     /gene="aroD"
                     /locus_tag="ACL3G6_000167"
     CDS             43289..43966
                     /gene="aroD"
                     /locus_tag="ACL3G6_000167"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HGR0544769.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            43956..44810
                     /locus_tag="ACL3G6_000168"
     CDS             43956..44810
                     /locus_tag="ACL3G6_000168"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HGR0544770.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            44829..45896
                     /gene="aroB"
                     /locus_tag="ACL3G6_000169"
     CDS             44829..45896
                     /gene="aroB"
                     /locus_tag="ACL3G6_000169"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HGR0544771.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     IAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            45906..47072
                     /gene="aroC"
                     /locus_tag="ACL3G6_000170"
     CDS             45906..47072
                     /gene="aroC"
                     /locus_tag="ACL3G6_000170"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HGR0544772.1"
                     /translation="MRYLTAGESHGPRLTAIIDGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIENDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            47082..48185
                     /locus_tag="ACL3G6_000171"
     CDS             47082..48185
                     /locus_tag="ACL3G6_000171"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HGR0544773.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSEIILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            48196..48534
                     /locus_tag="ACL3G6_000172"
     CDS             48196..48534
                     /locus_tag="ACL3G6_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HGR0544774.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTDY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            48626..49909
                     /gene="aroA"
                     /locus_tag="ACL3G6_000173"
     CDS             48626..49909
                     /gene="aroA"
                     /locus_tag="ACL3G6_000173"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HGR0544775.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLSPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            49902..50378
                     /locus_tag="ACL3G6_000174"
     CDS             49902..50378
                     /locus_tag="ACL3G6_000174"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HGR0544776.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGESAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIVADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            50375..51223
                     /gene="pheA"
                     /locus_tag="ACL3G6_000175"
     CDS             50375..51223
                     /gene="pheA"
                     /locus_tag="ACL3G6_000175"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGR0544777.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            51220..52494
                     /gene="psr"
                     /locus_tag="ACL3G6_000176"
     CDS             51220..52494
                     /gene="psr"
                     /locus_tag="ACL3G6_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HGR0544778.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     RNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSSPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            52773..53618
                     /locus_tag="ACL3G6_000177"
     CDS             52773..53618
                     /locus_tag="ACL3G6_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR0544779.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGTLR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSYKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKDPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            53608..54711
                     /locus_tag="ACL3G6_000178"
     CDS             53608..54711
                     /locus_tag="ACL3G6_000178"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR0544780.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            54713..55699
                     /locus_tag="ACL3G6_000179"
     CDS             54713..55699
                     /locus_tag="ACL3G6_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0544781.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQIYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            55715..57148
                     /locus_tag="ACL3G6_000180"
     CDS             55715..57148
                     /locus_tag="ACL3G6_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HGR0544782.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFIAKMLTKEN"
     gene            57177..58211
                     /locus_tag="ACL3G6_000181"
     CDS             57177..58211
                     /locus_tag="ACL3G6_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGR0544783.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            58353..59090
                     /gene="mecA"
                     /locus_tag="ACL3G6_000182"
     CDS             58353..59090
                     /gene="mecA"
                     /locus_tag="ACL3G6_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HGR0544784.1"
                     /translation="MKMKQISDTTLKITISLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFAEDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            59241..60527
                     /locus_tag="ACL3G6_000183"
     CDS             59241..60527
                     /locus_tag="ACL3G6_000183"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HGR0544785.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVVHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            60529..61398
                     /gene="thrB"
                     /locus_tag="ACL3G6_000184"
     CDS             60529..61398
                     /gene="thrB"
                     /locus_tag="ACL3G6_000184"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HGR0544786.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            61648..62586
                     /gene="msrB"
                     /locus_tag="ACL3G6_000185"
     CDS             61648..62586
                     /gene="msrB"
                     /locus_tag="ACL3G6_000185"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGR0544787.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            62644..64368
                     /locus_tag="ACL3G6_000186"
     CDS             62644..64368
                     /locus_tag="ACL3G6_000186"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0544788.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISTELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISVKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYCEIN
                     ASQHGKED"
     gene            64370..66121
                     /locus_tag="ACL3G6_000187"
     CDS             64370..66121
                     /locus_tag="ACL3G6_000187"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0544789.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKKSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     TSDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRF
                     YPISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVI
                     AAAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATS
                     SIDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMD
                     RKGKYYQMQKAAAFSSE"
     gene            66468..67727
                     /locus_tag="ACL3G6_000188"
     CDS             66468..67727
                     /locus_tag="ACL3G6_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HGR0544790.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    67803..67938
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            67977..68477
                     /gene="rplJ"
                     /locus_tag="ACL3G6_000189"
     CDS             67977..68477
                     /gene="rplJ"
                     /locus_tag="ACL3G6_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HGR0544791.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            68553..68921
                     /gene="rplL"
                     /locus_tag="ACL3G6_000190"
     CDS             68553..68921
                     /gene="rplL"
                     /locus_tag="ACL3G6_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HGR0544792.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
BASE COUNT        20084 a        12892 c        15564 g        20485 t
ORIGIN      
        1 aatatatctc ggtttgatta tctcgtttat accgccgata ttgcttacat tctttattct
       61 aaagactcaa gggacatcgc ttggtattaa gcatatttca aacttttatg ctatgctcgg
      121 tatgttaatg gctgttatac atgctaaccg aattattagc agggattttt cccacaatac
      181 gatcagttta ttttataatc aacagaaaaa tcggatgatt tacctcttgt ctaattttct
      241 atatgccatc tcagtttcca ttatttatgc tttgaatggc attgtgttac tagtcatagt
      301 aagtaaattg ggtattccag gtgatttagg attagatttt atagtagcta ttgtagtcaa
      361 tacaattttg ttagtcctgt tttattttct attatcttac attttctatt tatacaaatt
      421 gaaaagtggc ttggtatttg gtattttagt agctttacta ctctttatcc ctaatatatt
      481 aaatacgatg atgatgaata ctagtaatga tttgtttatc aaagcaattg aacttcttcc
      541 tttttattct ttacctgtat ttgtgacttc aaatacgatg tctattagtc agtatcttgt
      601 ggtaatcact acaatcattt tattgtactt tttcactctc aagaaaagca agaagtattc
      661 attttagttt catttagtat tattttgcat acctaaaata caataaaaaa atcagtcatc
      721 ttggtatgct cctgctttca ctattcaaca cgtttttgac ttatactagg ctcatttcca
      781 aaagcattat ataatagtga tatgaaacca actaaactaa acaagaaata taagcaataa
      841 aaactcgttt aaaagattct actaaagcta atactaaata aaaataaaag agtaaactag
      901 gaagtttatt tcaaacaacc taaaatactg attttcggct gaagataata ctggagtgca
      961 aattaatggg gttataataa atagctgata gcttgtgttg gttttggatt ttttaagagt
     1021 agatgagtat taaaactata aggaggacga aggtggctaa aaatttaaaa ttaaaattag
     1081 ctcgggtaga gcgtgattta acacaaggtc aactggcaga ggctgtcggg gtgacacgcc
     1141 agactattgg tttgatagag gcgggaaaat acaatcccag tctctcgctc tgccagtcta
     1201 tttgcagatg tttagggaaa accctagacc aactattttg ggaggaagaa gatgaaaaat
     1261 agattttatt attatcaatt actagacgaa agagaagaac aactgttcaa taaagcgggc
     1321 tctgaaagtt tctatatctg cattgctttg tcgctcctat cttatatcat ttcagtatta
     1381 gcaccaagcc tttttaattc taatatgctg ctaatcgtta tcatcatagg gacattttac
     1441 tttttcaatc gtgcccgtta tctgggagtg acctactata gtcgttttca ttttacgatt
     1501 ttgggttgtt ttttcctaac cttggctatt acggctcttt tgatgttgca gaattatcaa
     1561 ttcaacatag aaatttatca gcacaatcct ttgaatttta aatacctgtc tgcttgggtc
     1621 attacttatg tcatttacct tccgtgggtc tttattggca atcttggtct taagagctat
     1681 ggcgaatggg ctcagaaaaa atttgaacaa gatatggatg aattggagag tggagaatag
     1741 cttgttactc ttttctcaat ccagctaaaa tgtgatataa tagtattaat ttattggaat
     1801 acatgaaagt tcttgaaaat tttcatgggt ttctagctaa ggaagtagga aaagtatgta
     1861 tccagatgat agtttgacat tgcacacgga cttgtaccag atcaacatga tgcaggttta
     1921 ctttgaccaa gggattcaca ataagaaggc ggtctttgag gtgtatttcc gccaacagcc
     1981 ttttaagaac ggctatgcgg tttttgcagg tttggaaaga attgtgaact atcttgaaga
     2041 cttgcgtttt tcagatagtg atatagccta tttggagtcg cttggttatc atggggcgtt
     2101 cttggattac cttcgcaatt tcaagttgga gttgaccgtt cgttctgccc aagaagggga
     2161 tttggttttt gctaatgaac cgattgtgca ggtggaagga cctctagccc aatgtcagtt
     2221 ggtcgaaacg gctcttttga acatcgtcaa ctaccagacc ttggtggcga cgaaggcagc
     2281 tcgtattcgt tcggttatcg aagatgaacc cttgatggag tttgggacac gtcgggctca
     2341 agaaatggat gcggccatct ggggaacacg cgcagctgtg attggtggcg ccaatggaac
     2401 cagcaacgtg cgtgcgggta agctctttga cattcctgtt ttgggaaccc atgcccatgc
     2461 cttggtacag gtttatggaa atgactatga agctttcaag gcttacgctg cgacccacaa
     2521 aaattgtgtc tttcttgtgg atacctatga cacccttcgc atcggtgtac cagctgccat
     2581 tcaggtggcg cgtgagctgg gtgatcagat taactttatg ggtgtgcgga ttgactctgg
     2641 ggatattgcc tacatttcta agaaagtccg tcagcaactg gacgaggctg gatttacaga
     2701 ggctaagatt tatgcttcta atgatttgga cgaaaatact atcctcaacc tcaagatgca
     2761 aaaggccaag attgatgtct ggggcgtggg taccaagctg attacagcat atgaccagcc
     2821 agctcttggg gcggtttaca agattgttgc aatcgaagat gaaactggtc agatgcgcaa
     2881 tacgattaag ctgtctaata atgctgaaaa agtctctacg ccaggtaaga agcaggtgtg
     2941 gcgcattacc agtcgtgaaa aaggtaagtc agaaggtgac tacatcactt atgatggtgt
     3001 ggatattagc tacatgacag aaatcaagat gttccatccg acctatacat acatcaagaa
     3061 gacggttcgt aattttgatg ccgttcctct cttggtggat atcttcaaag aaggaatatt
     3121 agtttacaac ttgcctagtt tgactgacat tcaggattat gcccgtaaag aatttgacaa
     3181 gttgtgggat gagtataagc gtgtgctcaa tccgcagcac tatccagtgg atttggcgcg
     3241 tgatgtatgg caagataaga tggacttgat tgataagatg cgcaaggaag cccttggtga
     3301 aggagaagaa gaatgagttt gcaagaaacg attatccaag agctgggtgt caaaccagtg
     3361 attgatgccc aggaagaaat ccgtcgttct attgatttct taaaaagata tctgaaaaaa
     3421 catcccttcc taaaaacctt tgtactaggg atttctgggg gacaagactc aaccttggca
     3481 gggcgtttgg cgcaattagc tatggaagaa ctgcgagctg aaacgggaga cgacagctac
     3541 aaatttatcg ctgtccgcct gccatacgga gtgcaagctg atgaagcaga tgctcaaaaa
     3601 gccctagcct tcatccagcc agatgtcagc ttggttgtga atatcaagga atcagctgat
     3661 gccatgacag ctgcagttga agcgacaggt agtcctgttt cagacttcaa caaggggaat
     3721 atcaaggcac gttgccgtat gattgctcag tatgcccttg ctggttccca tagcggagcg
     3781 gtcattggaa cagaccacgc cgcggaaaat atcacaggtt tctttaccaa gtttggtgac
     3841 ggcggtgcgg atattctccc tctttaccgc ctcaataaac gccaaggaaa acagctcttg
     3901 cagaaacttg gcgcagagcc agccctttat gaaaaaatcc caacggcaga cctagaagaa
     3961 gataaaccag gcctagctga cgaagtcgca cttggagtca cctatgcaga gattgacgat
     4021 tacctagaag gcaaaacaat cagcccagaa gctcaagcga ccattgaaaa ctggtggcac
     4081 aaaggccaac acaaacgcca cttacccatc accgtatttg atgacttttg ggagtaaaaa
     4141 cctccattgg aggtttttac cctgagccta gaaatgagaa agtgagagaa agtccggggg
     4201 atcttgaacc ccgagtttag aaataagaaa atgaggcaga ttcggtaact cgaagagttc
     4261 gatttcatcg tcttacccct gcaacgatga ctaggtttga aaaagcttgc tagatcgcat
     4321 ttcaaaccag gcagcgactg cgtcaagaaa ttagaagaca aactcgtttt ctagctgtta
     4381 ctgagttgag tctttttact acgagcatag aaataaggaa gtgaggtagc atcatgaaat
     4441 ctatcggtac gcaaatatta cagacagaac gtttgatttt aagaagattt gtggagagtg
     4501 atgcagaagc catgtttcaa aattgggctt catccgctga gaatttgacc tatgttacct
     4561 gggatcccca tcctgatgtc gaaatcactc gaaactcgat tcgcaattgg gttgcttcct
     4621 atactaatct caactattac aaatgggcca tttgtctaaa agaaaaccca gagcaagtga
     4681 taggagatat cagcatcgtt aagatagacg aggctgattt aagctgtgaa atcggctatg
     4741 tgctaggcaa ggcttactgg ggacatggta tgatgacaga ggccttgaaa gctgtcttgg
     4801 acttttgttt tactcaagca ggttttcaaa aggtcagagc acgttatgcc agtctcaacc
     4861 cagcttcagg tcgtgtcatg gaaaaggctg gaatgtccta tctacaaacc attgttaatg
     4921 gtgtagagag aaaaggctat cttgcggatc ttatttatta tggtataagt agggaagaat
     4981 gttgaattct attttctgtt tctatcgaag tcaactattt attgtaaata taataattag
     5041 cattccaagt ttatttgaaa ctttaaaata gcatattgat tagtacaaga cagatgttct
     5101 agttccttct ttaatctggt ttagtattag ttaaaaaatc gcttgaagct tgtaactaag
     5161 agggagctaa tcgactaggt tctccagccg aacaggtggt aatgtacttt ttatagtgta
     5221 atcctagctg ttgttaaatt taaaatagaa tcctctatcg agttagggaa ttaaattcaa
     5281 ccaattttat ttatgttttt ctatcaaatt atctaatatt aaaatagtct cattctgatg
     5341 agaaaactat tctatttata ctgcatagtt gtataaggaa tgatgaaaga tgagtgaaag
     5401 ttatcaagtt ggaatgtttg tatctaaata tattagcatg tatttagata agatgtctgc
     5461 aatcctttat atatgagatt gattacgata tagttaaagt gttagttcaa taatcaatat
     5521 atcattctaa gtctatttta tatataaagt atattgttta acgtttgata gaaaagatgc
     5581 tatactagaa gtaggatgta atggcaaaat ctaatactaa taagcgctat gcaatacgta
     5641 aactcggaaa gatttttggt tctgcggtaa tcgggctaac tttattttta ggaggaatct
     5701 gaatacaagt tttgttcatg ctgctgatgg gattcaatat gtcagagatg atactagaga
     5761 taaagaagag ggaatagagt atgatgacgc tgacaatggg gatattattg taaaagtagc
     5821 gactaaacct aaggtagtaa ccaagaaaat ttcaagtacg cgaattcgtt atgaaaaaga
     5881 tgaaacaaaa gaccgtagtg aaaatcctgt tacaattgat ggagaggatg gctatgtaac
     5941 tacgacaagg acctacgatg ttaatccaga gactggttat gttaccgaac aggttactgt
     6001 tgatagaaaa gaagccacgg atacagttat caaagttcca gctaaaagca aggttgaaga
     6061 agttcttgtt ccatttgcta ctaaatatga agcagacaat gacctttctg caggacagga
     6121 gcaagagatt actctaggaa agaatgggaa aacagttaca acgataactt ataatgtaga
     6181 tggaaagagt ggacaagtaa ctgagagtac tttaagtcaa aaaaaaagac tctcaaacaa
     6241 gagttgttaa aaaaggaacc aagccccaag ttcttgtcca agaaattcca atcgaaacaa
     6301 aatatctcga tggcccaact cttgataaaa gtcaagaagt agaagaagta ggagaaattg
     6361 gtaaattact cttactacaa tctatactgt agatgaacgt gatggaacaa ttgaagaaac
     6421 tacttctcgt caaattacta aagagatggt aaaaagacgt ataaggagag ggacgagaga
     6481 acctgaaaaa gttgttgttc ctgagcaatc atctattcct tcgtatcctg tatctgttac
     6541 atctaaccaa ggaacagatg tagcagtaga accagctaaa gcagttgctc caacaacaga
     6601 ctggaaacaa gaaaatggta tgtggtattt ttataatact gatggttcca tggcaacagg
     6661 ttgggtacaa gttaatggtt catggtacta cctcaacagc aacggttcta tgaaagtcaa
     6721 tcaatggttc caagttggtg gtaaatggta ttatgtaaat gcatcgggtg agttagcggt
     6781 caatacaagt atagatggct atagagtcaa tgataatggt gaatgggtgc gttaacagat
     6841 tcctccctgc gacaaaattg ataatagtat gtctgaatat ataattatat ataaaaagct
     6901 atagataagg tcatcttata gcgactataa aaaagtgaac aagcctagtc ttctgtacat
     6961 tagaattcag atttgttcac tttttgttta atactcaatg aaaatcaaag agcaaactag
     7021 aaaactagtc gcaggttgct caaagtactg ctttgaggtt gtagatagaa ctgacgaagt
     7081 cagtcacata tataatccaa ggtgacgttg acgcggtttg aagagatttt tgaagagtat
     7141 aagtctttga ttttgagact aaggagagtc agggtcaaag tagtgaatga ttctgaaata
     7201 actcataata gtctcttgag aggacagata agagtaacaa atatggtgct actcatgtgt
     7261 cttgcatttt gatttacaaa cagcgaagaa aatataggaa gctgaaataa aatatagatg
     7321 aatcaatttg gagagtcaac gcaatctatg gcaatatttt cgaagctagg gggaagcatt
     7381 ttaatttcaa tgtactaggc ctcttctaca gctagctaga gtttcaattg tagatgttct
     7441 ttgaaataat atcttagcga tttattggta ttagaagatt tagagaaatt ctttctcaat
     7501 aaataaacat ggcgtcacca aaactgaaga agcggtagtg ttcttggatg gcatggtggt
     7561 aggcatctaa gactaattca cggcctgcaa aggcagaaac caacatgacc agagttgatt
     7621 ttggcaggtg gaagttggtt gagaaggcat ccacgacctt ccactcatac ccaggtttga
     7681 taaagatatt ggtccaacca gaatctgctt ggatttgccc atcaaacttg gaaccaatag
     7741 tttccaaggt gcggatagaa gtggttccga cagcgatgac acgaccacca ttttctttga
     7801 cagagcgaag ggtggcagca gcttcctcag aaagttgata gaactctgag tgcatttcgt
     7861 gttcgtccag attatccaca gaaacaggtc taaaggttcc gagtccgaca tggagagtca
     7921 gatagactag atgaacaccc ttagcttgga tttctgccag cagttctttg gtgaagtgaa
     7981 gaccagcagt cggtgctgca gcagagccgc tttccttggc gtagacggtt tgataacgtt
     8041 cacggtcatc taatttttcg tggatataag gtggcagagg catttctccc agactttcca
     8101 agacttctag gaaaattcct tggtattcaa agcggacaat gcgtcccccg tgggtcaatt
     8161 cttctgtaac gacagcgctg aggcggccat caccaaagct gatacgagta ccgaccttga
     8221 ggcgtttggc aggtttagcc agaacttccc actcgtctcc actagtgttc ttaaggagga
     8281 gaagttccac atgacctcct gtctccactt tttgaccata gaggcgggca gggagaactc
     8341 gggtgtcgtt catgacaagg gcatcaccag gttccagcat atcaataata gagtggaagt
     8401 gtttatcttg catttctcct gtctcacggt tgacgatgag gagtttggag gcatcacgtt
     8461 tttcaagggg cgtttgggca atcaattcct ctggcaagtg gaaatcaaaa tcagctgtat
     8521 tcatatattt gttcattctt tctaagttct aatcctatcc attataacac gtttcaagtt
     8581 tggacgctct ttttttagaa attaaatcgt tttcacttga caaaaattgg tctataccat
     8641 ataataaata tagacagaaa tggaggatga aaagatgaaa gttattaaag ttgaaaacca
     8701 agttcaaggt ggaaaagttg cttttgagat tttgaaggaa aaattggcta atggagctca
     8761 aactctagga cttgcgacag gaagtagccc acttgaattt tacaaggaaa ttgttgagag
     8821 tgaccttgat ttttcaaatc taaccagtgt caaccttgat gagtatgtgg gccttgatgg
     8881 ggacaatcca cagtcttatc gttacttcat gcaagaaaac ttgttcaacc aaaaaccatt
     8941 taaagaaagt ttcttgcctc gtggtgttaa ggacaatgct gaagctgaag ttgaacgcta
     9001 caaccaaatt ttggctgacc atccagttga cctccaaatc ttgggaatcg gtcgcaatgg
     9061 gcatatcggc tttaatgagc ctggtactcc atttgacagt caaacgcatc tagtagaact
     9121 tgaccagtct actatcgaag ccaatgcacg cttctttgcc aagattgaag acgtcccaac
     9181 ccaagctatt tcaatgggga ttaaaaacat tttggatgcc aagtctatta ttctttttgc
     9241 ttacggtgag tcgaaagcag aagccattgc cggaacagta tctggcccag tgactgagaa
     9301 cctacctgca agtagcctcc aaaatcaccc tgatgtaacc atcatcgcag atgctgaagc
     9361 gcttagctta ctcgaaaaat aaaaagtata agaaccgctt gctctttgga gtgagtggtt
     9421 ttagacatat aaaacttcaa cttaacttta ggaggacaca tgaataaaga agaattttta
     9481 aaaataaaag aagcatataa gagtgctaga acggaagaaa gaaaaagtat aataggcttc
     9541 attacaaaaa agaaagataa ggaggggaat tttcttttta ctaagtcaaa agataaacca
     9601 tataccacaa gaaatcaata ttcaggaggc ggaggaaata aaaagtacac ctcgggtagt
     9661 agattatcta ggccatatga tttatcaaat cacatgtgga ttgatttgtc atataaagga
     9721 aatgacatct taatctcttt acagtctttt gatattgatc caaatagtaa agaacttcac
     9781 gtcttatatg atagaatagg catcttattt gaacaatcta aaaaaattcc aatttttaaa
     9841 gattgctata caataactaa agtcagtgat gcttttctta aaatggaaac aacaaactgg
     9901 gaattacctt tatctaaagc agatatggaa gagatggtga actatattat taatcattat
     9961 gaagaataaa aaacttagtt tcctcttgac aattattcct tttacgtgta gaatgaaata
    10021 gatattgaac ttgaagggag tgaaaaaaat gtctaaaaca gtagtacgta agaatgaatc
    10081 tcttgacgac gcacttcgcc gtttcaaacg tgcggttact aaagctggta ctcttcaaga
    10141 aacacgcaaa cgtgaattct atgaaaaacc ttctgtaaaa cgtaaacgta aatcagaagt
    10201 agctcgtaaa cgtaaaaaat tctaattgaa atgaaaggct agagaaatct agtccttttt
    10261 cttttaaata aatactccaa agcctgcaaa aatctgaaac ttcctcctac aatttgatat
    10321 aatagagaga agaactcatt tgaaggagga aatgatgtcg gttttagtaa aagaagtgat
    10381 tgaaaagctt agactagaca ttgtctatgg tgaaccagaa ttgcttgaaa aggaaatcaa
    10441 tatagcggat attacgcgac ctggtcttga aatgacaggc tattttgact actatacacc
    10501 agagcggatt caacttttgg ggatgaagga gtggtcttat ctgatcagca tgccttccaa
    10561 cagccgttat gaagttttga aaaaaatgtt tctacctgag acaccagcag tcattgttgc
    10621 ccgtggtttg gtggttccag aggagatgtt aaaggctgct agagaatgta agattgctat
    10681 tttaaccagc cgtgcagcta ccagtcgttt atctggagag ttatctagct atctggattc
    10741 tcgtttggca gaacgtacca gtgtgcacgg tgtcttgatg gatatttatg ggatgggcgt
    10801 cttgattcag ggagatagtg gaattggtaa gagtgagaca ggtcttgagc ttgtcaaacg
    10861 tggtcaccgt ttggtagccg atgaccgtgt cgatatcttt gccaaggatg agattactct
    10921 ctggggtgaa ccagctgaaa ttttgaaaca cttgattgaa attcgtgggg ttggtattat
    10981 cgatgttatg agtctctacg gtgcgagtgc tgtcaaggat tcttcacagg ttcagcttgc
    11041 tgtctatttg gaaaattacg atacgcataa gacctttgat cgtcttggaa acaatgcaga
    11101 ggaacttgaa gtttctggcg tagccattcc tcgtattcgt attccagtta aaacaggtcg
    11161 taatatctct gttgtgattg aggcagctgc catgaattat cgtgccaagg aaatgggctt
    11221 tgatgcgacc cgtttgttcg acgaacgact gacaagtctc atcgctcgaa atgaggtgca
    11281 aaatgcttga tccaattgct attcaactag gacccctagc cattcgttgg tatgccttat
    11341 gtattgtgac aggcttgatt cttgcggttt atttgaccat gaaagaagca cctagaaaga
    11401 agatcatacc agacgatatt ttagatttta tcttagtagc ctttcccttg gctattttag
    11461 gagctcgtct ctactatgtt attttccgat ttgattacta tagtcagaat ttaggagaga
    11521 tttttgccat ttggaatggt ggtttggcca tttacggtgg tttgataact ggggctcttg
    11581 tgctctatat ctttgctgac cgtaaactca tcaatacttg ggattttcta gatattgcgg
    11641 cgcctagcgt tatgattgct caaagtttgg ggcgttgggg taatttcttt aaccaagaag
    11701 cttatggtgc aacagtggat aatctggatt atctacctgg ctttatccgt gaccagatgt
    11761 atattgaggg gagctaccgt caaccgactt tcctttatga gtctctatgg aatctgcttg
    11821 gctttgcctt gattctgatt tttagacgga aatggaagag tctcagacga ggtcatatca
    11881 cggcctttta cttgatttgg tatggtttcg gtcgtatggt catcgaaggt atgcgaacag
    11941 atagtctcat gttcttcgga cttcgagtgt cccaatggct gtcagttgtc cttatcggtc
    12001 tcggtataat gatcgttatt tatcaaaatc gaaagaaggc cccttactat attacagagg
    12061 aggaaaacta aatgttagaa gttgcatata ttcttgttgc cttagctttg attgtctttt
    12121 tggtctatct gatcattact gtacaaaagc ttggtcgtgt catcgatgaa acagaaaaga
    12181 cgattaaaac cttgacttca gatgtggatg tgaccttgca tcacaccaat gagttgttgg
    12241 ctaaggtcaa tgtcttggca gatgatatca atgtcaaggt ggctacgatt gatccactct
    12301 tcagtgctgt tgcagattta tctctatctg tttcagacct caatgaccat gcgcgtgtct
    12361 tgagcaagaa agcttcatca gctggttcaa aaacactcaa gactggtgca agtctgtcag
    12421 ctcttcgtct tgcaagtaaa tttttcaaaa aataaaaaag gagaatcctt atgggtaaat
    12481 tatcctcaat ccttttagga acggtttcag gtgcagctct tgccttgttt ttaacaagtg
    12541 ataagggcaa acaagtttgc agtcaggctc aagattttct agatgatttg agagaagatc
    12601 cggagtatgc caaggagcaa gtctgtgaaa aactgacaga agttaaggag caggctacag
    12661 attttgttct gaaaacaaaa gaacaggttg agtcaggtga aatcactgtg gacagtatac
    12721 ttgctcaagc taaatcctat gcttttcaag cgacagaagc atcaaaaaat caattaaata
    12781 atctcaagga acaatggcaa gaaaaagccg aagctcttga tgactcagaa gagattgtga
    12841 ttcatataac agaagaataa accatcacca tctccggacg gactatgtat ctggggatgg
    12901 tgatttttat ctggaatcta gtctttgtgg tataataatt actatgcaga aaaaaccaac
    12961 gtcagcctat gtgcacatcc cattttgtac ccagatttgt tattattgtg atttttcaaa
    13021 ggtcttcatc aaaaatcagc cagtcgacag ctatttagag catctgctgg aagagtttcg
    13081 ttcttatgat attgaaaagt tgtcaaccct ttatatcggt ggtggaacac cgacagccct
    13141 gtcggctccg caactggagg tgttactgaa tggcttgact aaaaacttgg atttgtctgt
    13201 cttggaagag ttgaccattg aagccaatcc aggcgatttg gatgcggata agatagctgt
    13261 tttgaaaaat tcggctgtca atcgtgtttc gctaggtgtc cagacctttg atgataagat
    13321 gttgaaaaag attgggcgca gtcatttgga gaaggatatt tatgaaaata tcgatcgcct
    13381 gaaactggct ggttttgaca acatctccat tgatttgatt tatgctctgc ctggtcagac
    13441 catggagcaa gtaaaggaaa atgtggctaa agccattgga ttggatattc cccacatgag
    13501 tttgtatagt ttgattttag aaaaccatac ggtctttatg aaccggatgc gacgtgggaa
    13561 attgcctctg cctaaggagg aactagaagc ggagatgttt gagtacatca ttgcagagct
    13621 ggagcgagcg ggttttgagc attatgagat ttctaatttc tccaaacccg gttttgaaag
    13681 tcgtcataat ctcatgtact gggacaatgc tgaatactat ggtattggtg caggggcatc
    13741 tggttatgtc aatggagtac gctataaaaa tcatggtccc attcgtcatt atctcagtgc
    13801 ggttgaggaa ggcaatgctt gtattacaga agatcacctg agtcaaaagg agcaaatgga
    13861 agaagaaatg ttcttgggac tccgcaagaa atccggggtt tccatggcgc gatttgagga
    13921 aaaatttgga cagtcttttg ctggacttta tggagaaatt gtcagagatt tggttcaaca
    13981 aggcctcatg cagattgagg gtgaccacgt tcgcatgaca aagagaggtc tctttttggg
    14041 agatactgta gcagaacgat ttattttgga gtaggatcat gggcttaact tatcaaatga
    14101 aaatgaaaat tccttttgat atggctgata tgaacggtca tatcaaactt ccagatgtga
    14161 ttttgctgtc actgcaagtt tcagggatgc aatcgattga actgggagtt agtgataagg
    14221 ccattttgga agactataat ctggtctgga ttatcgcaga atatgatatt gaggtggttc
    14281 gtttgcctcg ttttgcggaa gaaattacca tcgaaacgga agccttgagc tacaatcgac
    14341 ttttttgcta ccgtcgcttt actatttata atgaagcggg gcaggagctc atccatatga
    14401 tggcgacctt tgttctcatg gaccgcgaca gtcgaaaagt ccatgctgtt gaacctgaga
    14461 ttgtggctcc ttaccagtct gattttgata aaaaacttat ccgtggaccg aagtatgaat
    14521 ccttggaaga gccgatcagc aaggattacc atgttcgttt ttacgacttg gatatgaatg
    14581 gtcatgtcaa taacagtaaa tacttggact ggatttttga ggtcatggga gcggattttt
    14641 tgacccacta tattcccaag aaaatcaacc tcaagtatgt caaggaagtt cgaccaggtg
    14701 gggtgattac atcggctgtt gaacggactg gactggaaag caagcatgaa attacaagtg
    14761 atggggttat caatgcccaa gcaatcatta cttggcaaga aataaaaaag gtttagggag
    14821 aaatagatga aatataaagg ctatttaatc gatttagacg gaaccattta taaggggaaa
    14881 gaccgaatcc ctgctggaga gacttttgtt catgaattgc aaaagcggga cattccctat
    14941 ctctttgtaa ccaacaatac aacccgcact ccagagagtg ttaaggagat gttggctcag
    15001 aattttaata tcgatacgcc tctatcgact gtctacacag cgactttggc aaccatcgac
    15061 tatatgaatg atttggggct tgaaaagacc gtctatgtcg tcggagaagc aggactcaag
    15121 gaagccatca aggcggctgg ttatgtggaa gacaaggaaa accctgccta cgtggtagtt
    15181 ggtctggatt ggcaagtcga ctatgaaaaa tttgccacag caactcttgc tattcaaaag
    15241 ggtgcccatt ttatcggaac caatcctgac ctcaacatcc cgacggaacg tggtcttttg
    15301 ccaggtgctg gctcactgat tacgctgctt gaagtagcga cacgagtgaa gccggtttat
    15361 atcggaaaac caaatgccat cattatggac aaggcggttg agcacttagg tttggaacgt
    15421 gaagagttaa tcatggttgg ggacaattat ttgactgata tccgggctgg gattgacaat
    15481 ggcattccaa cactcttggt gacgacaggt tttaccaagg cagaagaagt agctggcctg
    15541 ccaatcgcac cgacacatgt ggtttctagc cttgcggagt gggattttga tgaaaactaa
    15601 attgaccttt tggggctcta tgctctttct cctctccctc tcaatccttc tgaccattta
    15661 tctggcttgg attttctatc ctatggagat tcagtggcta aacttaacga atcgagtcta
    15721 tctaaaacca gaaaccattc aatacaattt tcatatcttg atgaattatc tgaccaatcc
    15781 ttttagtcag gtcttacaga tgcctgattt tcgttcgtca gcagctggtc tgcaccattt
    15841 cgcagtggtc aagaatctct ttcatttggt tcagctagta gctctagtga cactgccaag
    15901 tttctatgtc tttgtcaata ggattgtgaa aaaggacttt ttgtctcttt atcgaaaaag
    15961 tctcctgact ctagtagtct tacctgtgat gattggactt gggggagttt tgattggttt
    16021 tgaccaattc tttactcttt tccatcaaat tctctttgtg ggagatgata cctggctttt
    16081 tgatccagcc aaggatcctg ttattatgat tttgccagag accttctttc ttcatgcctt
    16141 cctcctcttt tttgccctct atgaaagctt ctttgggtat ctgtgtctga aaagtcgtag
    16201 gaagtgaaat gaaagatgtt tttaatttgc atatataaaa atatatatcg tttaaaacca
    16261 tcgttaagag tgaattaacc aaatccaatt gtgtcaatcg ttcgcaaaca gcctattttt
    16321 cttgaaaaaa taggcttttt ttctaaaaat ccctagtcaa gcgccttatt tttttgtata
    16381 atagaagtag caaagtatag ataagaagag aaaagcatga ttacactatt tctatcaccg
    16441 agctgtacat catgtcgtaa ggctaaggcc tggttagaaa aacataaggt tccctttgtg
    16501 gaacacaata ttatgaccag tcctttaaca agaaaagaat tgcaacacat cctttccttg
    16561 accgaaaatg gtactgatga catcatttca actcgttcaa aaatttttca aaaattgaat
    16621 attgatgtag agagtatttc ggtatcggaa ttgcttcatt tgattgagca gtatcctagt
    16681 cttttgcgtc gtccaattat tattgatgcc aagcgtatgc aaatcggttt taatgaagat
    16741 gagattcgtg cttttctccc tcgtagttat cgtaagcaag aactaaaaga agcaagaatg
    16801 agagctggta ttagttaatg aacaaacagt atagttaccc actagatttg tcgtggagca
    16861 ctgaagaact tgcttcagtg ctttcttttt ttaatgatgt tgaagctgcc tatgaaggca
    16921 aagtagaggc taaaaagtta ctggactcct ataagggatt caaagcggtc gtgccaagca
    16981 agagcgaaga gaaacgtttg ggacgagaat ttgaaacggt tagtggctat tcactttacc
    17041 gagcagttca ggctgccaaa gaaaaagggg aaggaaagat ttctcttgga aagtaaattt
    17101 gaatttgcta aagagcttgt taagaaagca ggccagtaca ttcttgacca tatgcaggaa
    17161 gacttgcgtg ttgaaaccaa gtcctcttca acagatttgg tgaccagact ggacaaagaa
    17221 gttcaggaac tcttggttgg tgagattttg tcccgttatc ctgaggataa gatttgtgct
    17281 gaagaaggtt gtctgcgagc ctcggttcaa gagggcaagg tttgggtcat tgatcccatt
    17341 gatggtacca ataattttgt agcccagcag gaagattttg ctgttatgat ggcttatttt
    17401 gaaaatggtc agggacagtt tggtctgatt tatgatgtgg tcaaagggga ttgttaccac
    17461 ggtggtgggg aatttccagt ttgtctaaat gataggcccc tagctccttt taaaactaaa
    17521 ccacttggag attttctcat tgcagggaat agtggtatgc tggaaaccaa tgaatggggg
    17581 ctggctgatt tgagccgatc ggttcttggt gttcgtgtct atggaagtgc ggccattagt
    17641 tttgccaaga ttttgtcagg gcgtttgttg acctatctca cttatctgca accatgggat
    17701 tatgccgcag ctagtatttt aggggaaagt ctgggctatc gggttgtgac cctttttggt
    17761 gaagctcctg attttcaaac cagacagccg gtcatgatgg tgcctcttga gatgcaggag
    17821 gaaattcagt cctatattta cgaaaggaaa agaacttaaa tgcaatttcc agaaggattt
    17881 gttgaaaaat ataaagagat actaggagat gaggcaagag attttcttgc ctcttttgag
    17941 gaggaagcgg tttcggcctt tcgggtcaat cccttaaaag aagagcaact ttccttttct
    18001 gatgccatta ctcaaacccc ttggggccac tatgggaagg tttcagggaa atcgcctgag
    18061 catgctacag gtttagttta ttcgcaagaa cctgctgctc aaatggtggc tcaagtagcc
    18121 caacccagtc ctggtatgaa ggtcttggac ttggctgctg caccgggggg caaatcaact
    18181 caactggcag cctatctagc aggtgagggg ctacttgttt ccaatgaaat ttcaagcaaa
    18241 cgggctaaga ttttggttga aaacatggag cgttttggag cgacaaatgt cgtggtgacc
    18301 aatgaatctg ccgaccgctt ggtcaaggtc tttaaaggct attttgactt aatcgttctt
    18361 gatgcccctt gctctggtga aggaatgttt cgtaagcaac ctgatgctat ggactattgg
    18421 agcttagatt atccgagtca atgtgctagc ttgcaaagag aaattctgga ggatgcagtg
    18481 accatgttag ctgaaggtgg tcgtctggtt tattcgacct gtacctgggc acccgaggaa
    18541 aacgaagaga ttgtcaattg gttgctggaa gagtatgatt ttgacttgtt gccagtagag
    18601 catatcaatg gaatggtagc tggtattgac ctgccagaaa cggctcggat gtaccctcat
    18661 cagtttaagg gagagggtca gtttgttgcc catctacagt ttaagggtaa caatccagct
    18721 cctaaattta aggcaagtaa gagtaacctc agccgtgaac aagttgcctt gtggcaggaa
    18781 tttgcccaaa accatttgaa ggtcaatcta ccgggtatct tgcagacttt tggagaccag
    18841 ctttatctct tgccagaact tttgccagat ttagggaagc tcaagattgc tcgcaatgga
    18901 ctgcatctgg gcacttttaa gaagaaacgc tttgagccca gtttcgctct tggtttagcc
    18961 ttgaaaccga gtcaggtcga acagtcggtt gaaattggcc aagaagcgtt tgtcaagtat
    19021 gcggctggag aaaccgttca gctggcagaa agtctgccaa atggttggta ccaagttttg
    19081 gttaaaggca atggcttggg ctttgcaaag gttactggaa atgttttgaa aaattatttt
    19141 ccaaaaggcc tcagattcaa atgaaaatgc tagtcaaata tcttattcta tgttatagtg
    19201 aaagtatgga tttttttagt aggatgattc ttgatatctt gattgccatc acatgtagtt
    19261 ttactactcg atgaaaatca aagagcaaac taggaagcta gccatagata gctcaaaaca
    19321 ctggtttgaa gagattttca aagagtacaa gaagtttagt tattagcgtt cttaccgctt
    19381 gtaaactaga tttctcataa aatagaatct tttcctttta gttgtaaact agtctgggag
    19441 agtagagagg tttgagatac ctttctagct tttggattat catctgagga gagtaatttc
    19501 ccttgcatta aaaaggggaa aaagagacac gaaatgatta taatgggtga caatggggga
    19561 agggatagac aagagatttt atccacatat gaaaaaagga ggttaggaaa gagtaatata
    19621 gcctatatta tataaataat caattgcgca gaaatttggt aagaattcat gcgtcaactc
    19681 ataaagaact acttaaaaaa ttcacagtat tcataattat tttcgaggag aaaaacagtg
    19741 aaaaaaagaa aaaagcttgc tctgtctctt atcgcttttt ggctgacggc ttgtttagta
    19801 ggctgtgcta gctggattga tcgtggagaa tccataacgg ctgttggctc aactgccttg
    19861 caacccttgg ttgaagtagc ggcagatgaa tttggcacga tccatgttgg aaaaacggtc
    19921 aatgtccaag ggggaggttc tggtacaggc ttgtcccagg ttcagtctgg ggcagttgat
    19981 ataggaaact cagatgtatt tgctgaggaa aaagacggaa ttgatgcttc tgctcttgtt
    20041 gaccacaagg tcgcggtagc tggcttggct ctgattgtca ataaggaggt tgatgttgat
    20101 aacctaacga cagagcaact tcgtcaaatc ttcataggtg aggtaaccaa ttggaaagag
    20161 gttggtggta aggacttacc catctctgtt atcaatcggg cagccggctc tggttctcgt
    20221 gctacctttg atactgtcat tatggaaggt cagtctgcca tgcaaagtca ggagcaggat
    20281 tcaaatggag cggtaaaatc aatcgtatca aaaagtccag gagctatctc ttatttatct
    20341 cttacctata tagatgattc ggtcaaaagc atgaagttga atggctatga cttaagtcca
    20401 gaaaatataa gtagcaataa ttggcccttg tggtcttatg agcatatgta tacattgggg
    20461 cagcccaatg agttggctgc agaatttctc aattttgttc tctcggatga gacccaagaa
    20521 gggattgtca aaggattgaa gtatattccg attaaggaaa tgaaggttga aaaagatgct
    20581 gccggaactg tgacagtgtt ggaagggaga caataatgaa tcaagaagaa ttagctaaga
    20641 aaatgttgct tccatcaaag aattctcgtc tggagaaatt aggaaaaggt ttgacctttg
    20701 cctgtctttc tttgatagtc atccttgtgg ccatgatttt ggttttcgta gcgcaaaaag
    20761 gcttgtcgac cttctttgtc aatggtgtga atatctttga ctttcttttg ggaggaactt
    20821 ggaatccttc tagtaaagaa tttggtgccc ttcctatgat tttgggttcc tttatcgtta
    20881 ccattctctc agcccttatc gcaacaccct ttgctattgg tgcagcagtt tttatgaccg
    20941 aagtatcacc aaaaggggcg aagattttgc aaccagctat tgaactcctg gttgggattc
    21001 cttcagtagt gtatggattt attggcttgc aagtcgtcgt tccctttgtt cgcagtgtct
    21061 ttggtgggac tggttttggg attttgtcag ggatttccgt cctctttgtc atgattttgc
    21121 cgaccgtaac ctttatgaca acggatagct tgcgtgcggt tcctcgttat tatcgtgaag
    21181 ccagtttcgc tatgggagcc actcgctggc agactatctg gcgtgtgatc ttgaaggcgg
    21241 cccgttctgg tattttcact gcagtggtct ttgggatggc gcgtgccttt ggtgaggctt
    21301 tagctatcca gatggttgtc ggaaactcag ctgttatccc aacttccttg accacaccag
    21361 ctgcaacttt aacttctata ttaactatgg gaattgggaa cactgtcatg ggaactgtaa
    21421 ataataatgt tctctggtca ctggccttgg tactgctctt gatgagttta gtttttaaca
    21481 gtgtgattaa attgattacg aaagaaagag gaaagaaaaa ttatgcgcgc taagaaatta
    21541 gataaacttg caacagctgt cctctatacg attgctagca tcattgtgac aatcttggct
    21601 tccttgattc tctatatctt ggttcggggc ttgccccata tctcttggtc tttcttgact
    21661 ggaaggtctt ctgcttttca agcaggtggt gggattggca ttcagcttta caattccttt
    21721 ttcctattgg tcattacctt gattatttct gtacctcttt ctatgggagc tgggatttac
    21781 ttggctgaat atgctaaaaa aggtcctgtt accaactttg tgcggacttg tattgaaatc
    21841 ttgtcctctt taccatcagt ggtggtgggt ctctttggtt acttgatctt tgtagtccag
    21901 tttgagtatg gattttcaat catttcaggt gccttggcct tgacagtctt taacttgcct
    21961 cagatgacgc gtaatgtaga ggatagtttg aaacacgttc accataccca acgtgaggct
    22021 ggtctggctc ttgggatttc tcgctgggag acagtggttc atgttgttat tccagaagcg
    22081 cttccaggta ttgtaacggg tgtcgtcttg gcatctggtc gtatctttgg cgaagctgca
    22141 gctctgatct atacagcagg gcaatcggcg ccagctcttg actggtctaa ctggaatatc
    22201 ctcagtgtga ctagccccat ctctatcttc cgtcaagcag aaaccttggc tgtccatatc
    22261 tggaaagtca atagtgaagg cactattcca gatggaacca ttgtatcagc aggttctgcc
    22321 gctgtgctcc tgatctttat cctgattttt aactttggag ctcgtaagtt cggaagctat
    22381 ctacacaaga aattaaccgc tgcctaaagg agaagccatg tcaacatata actgggatga
    22441 gaagcatatc cttacctttc ctgaagaaaa agtagccctt tctactaagg atgtccatgt
    22501 ttactatggt aaaaatgaat ccattaaggg gattgatatg caatttgaaa gaaataaaat
    22561 tacagctttg attggtccgt cgggatcggg gaaatctacc tacttacgca gtctcaatcg
    22621 catgaatgat accattgata ttgctaaagt aactgggcag attctctatc gtggaattga
    22681 tgtcaaccgt ccagaaatca acgtttatga aatgcgtaaa cacattggaa tggtttttca
    22741 acgccccaat ccatttgcta agtcaattta ccgtaatatt acctttgcgc atgaacgtgc
    22801 tggagttaag gataagcaag tcctagatga aatcgtagaa acctcccttc gtcaggctgc
    22861 cctctgggat caggttaaag acgatctcca caagtcagcc ttgaccttat caggtggtca
    22921 gcaacaacgt ctctgtatcg ctcgtgccat ctctgttaag ccagatatcc tcttaatgga
    22981 tgagccagct tcagccttgg atccgattgc gaccatgcaa ctagaagaga ccatgtttga
    23041 gctcaagaaa gactttacca tcatcattgt aacgcataat atgcagcagg ctgctcgtgc
    23101 aagtgactat acaggcttct tttacttggg tgatttgatt gagtatgaca agactgcaac
    23161 tattttccaa aatgccaagc tacagtccac caatgactat gtatctggtc actttggtta
    23221 gaaaggaaac cgtatgacag atgcgatttt acaggtatca gacctgtccg tttattataa
    23281 taaaaagaag gctttgaata gtgtttccct atctttccaa cctaaggaaa ttacagcctt
    23341 gattggtcca tctggatcag ggaagtcaac cctcctcaag tctctcaacc gcatgggaga
    23401 tctcaatcca gaggtgacca caactggatc cgtggtgtac aatggtcaca acatctacag
    23461 tccgcgtaca gatacggttg aattacgtaa ggaaatcgga atggttttcc aacaacctaa
    23521 tcctttccct atgactatct atgagaatgt tgtctacggg cttcgtatca atggaattaa
    23581 ggataagcag gttctggatg aagccgtaga aaaagccttg caaggtgcct ctatctggga
    23641 tgaggtcaag gatcgtctat atgattcagc tattggattg tcaggtggtc aacagcagcg
    23701 tgtctgcgtg gcccgtgtct tggcaactag tcctaaaatc atcctcttgg atgagccaac
    23761 ttcggctttg gatccgattt cagctggtaa aattgaggaa accttgtatg gtctaaaaga
    23821 caagtacacc atgcttctgg taacccgttc catgcagcaa gcttcacgta tctctgataa
    23881 gacaggattt ttcctagatg gagatttgat tgaatttaat gataccaagc agatgttcct
    23941 tgatccccaa cacaaggaaa cggaagacta tattacagga aaatttggat aaggagatga
    24001 aagatgttac gatctcaatt tgaagaagat ttagagaaat tacataacca gttctacgct
    24061 atgggacaag aagtgctctc acaaatcaat cgtacggtac gtgcttttgt cacgcatgac
    24121 cgtgacctgg caaaagaggt catcgaagat gatgcagaag taaatgaata cgaagtgaaa
    24181 ctggaaaaga aatcatttga aatgatcgca ctccaacaac cagtctctca agatttgcgt
    24241 acagtcttga ctgtccttaa ggctgtatca gatgtggagc gtatggggga tcacgctgta
    24301 gccattgccc aggcaaccat ccgtatgaag ggggaagaac gcatcccagc tgtagaggaa
    24361 gaaattaaaa aaatgggacg tgaagttaaa agcgttgttg aagcagcact tgatctttat
    24421 cttaatggtt ctgttgacga cgcataccgg gtggcctcca tggatgagca aattaaccac
    24481 tattttgaaa ctatccgtga ccttgcgact gaagagatta agaaaaatcc agaagccatt
    24541 gttacgggtc gtgattattt ccaagttatt tcctacttgg agcgtatcgg tgactatgct
    24601 aaaaatatct gtgaatgggt tgtctacttt gaaacaggta agattgtcga actataaaat
    24661 agtttaattc tgtataaaaa ggagcttgaa atcaactgat ggctcctttt tttgaacgaa
    24721 aacatatttt tgagataaaa atttaaaaaa cacttgacaa gtaacttgga tatcgttata
    24781 attatacaaa attaacagag aggttgttta tttatgaaat caaaaaaatg gatatttgtt
    24841 ttatgtaatt ttcttgcaag tttcttctta gtagcttgcc agtcaggttc taatggttct
    24901 cagtcagctg ttgaggccat taagcaaaag gggaaattag ttgtggcaac cagtcctgac
    24961 tatgcaccct ttgaatttca atcattggtt gatggaaaga accaggtagt cggtgcagac
    25021 atcgacatgg ctcaggctat cgctgatgaa cttggggtta agttggaaat ctcaagcatg
    25081 agttttgaca atgttttgac cagtcttcaa actggtaagg ctgacctagc agttgcagga
    25141 attagtgcta ctgacgagag aaaagaagtc tttgattttt caatcccata ctatgaaaac
    25201 aagattagtt tcttggttcg taaggctgat gtggaaaaat acaaggattt aactagccta
    25261 gaaagtgcta atattgcagc ccaaaaaggg actgttccag aatcaatggt caaggaacaa
    25321 ttgccaaaag ctcaattaac ttccctaact aatatgggtg aagcagtcaa tgaattgcag
    25381 gctggaaaag tagatgctgt tcatatggat gagcctgttg cacttagtta tgctgctaaa
    25441 aacgctggct tagctgtcgc aactgtcagc ttgaagatga aggacggcga cgccaatgcc
    25501 gttgctctta gaaaaaatag tgatgatttg aaagaagtgg tagacaaggt catccaaaaa
    25561 cttaagaatg aaggaactta ccaaagctat cttgaaaaag cagcaagtct aactgaagtt
    25621 gaagaataag aaaaagcaga gttggatgtc attccaattc tgcttttaaa tagtttaaaa
    25681 cattttccag attgtctagg gacaccttgg caaattgata aggacaggtg cttaaatagg
    25741 cctcttcaaa gaagtccaag cccagttgac tgtgtttgag actggcgatt ttaggatact
    25801 gtctcaggtc tagcaataaa ccatcgtgta ggggataatg aggaagggga caaggtgttt
    25861 tagttatcct ttcctcgatt tgtttttggt aagattcatg attggtcaag cgagccaaac
    25921 gatttttttc aaacaattga ctgtcaatat agagtgacag ggccttttgc ataatgaggt
    25981 tgctgtcgta gtctaggata tttttgtagg ccacaaatgc ttctttgata gcatttggaa
    26041 gaatgagtgc tgtaatacga agggcaggaa aaaggctggt cgagaaggac ttgatataaa
    26101 tgacatgctc ctctgtatca agatagtgga aggtttggcc cttcttggag tccaaatcac
    26161 ccagataatc gtcctctacg atatagacat catacttggc agctaagtta agaatagatc
    26221 gtttgtcttg ctcagaatag gaatgtccca gaggatagtg aaatctagga atggtgtaga
    26281 aaaatttaat ttttcctgtt ttgaagtggc cttccagctc ctccaagtca atcccatcaa
    26341 tgcctcgttc aatcgtttga tagtccagcc cctgtgcaat caagaggcga ttcatccgat
    26401 ggtaggttgg ctgttccacc aagatttcct tggcttgtct aggaaaggat atttgagaga
    26461 ggataaacaa ggcttgttgg gttccagaag tcagtactag ttggttagcc ttgcagtaga
    26521 gagcttgctc aaataggagt ttgtgaatgg actgtcttag gtcttctaat ccttcttgat
    26581 tgtcatagta gttgaagagg tagttttctc gtccaatcaa ggtttcattg acacagagtc
    26641 ggaaatcgtc ataggcactg gcatgttcgt cggtaacctc gatttctagg tcttgatgtt
    26701 gcccttgttc taatacatag tagccactct gaggcttggc atagaggtat tgttcgtgcc
    26761 gtaattccag cagggctcgt tgaatggtgt ccttgctgca gtgaaagtca aggctcagtt
    26821 gacggataga aggcaggcga ctacccgtcg gaaatcgttc agactcgata ccatttttca
    26881 gataggaaac gacctctttg tacttgcttt gtttcttcat tccagacctc ccttgatttt
    26941 gttacattgt accctttttt ttccttcttg gcaatgtcta gagcgtttct ctcgttcaca
    27001 tctaggggca aatgtggtat acttaggagt aagatttata gaataacaga caagaaagtg
    27061 aatggataag aacgtgcagg aaccagtgaa attatttcaa tacaatactc ttggagcctt
    27121 gatggctggc ctttatggtg gtactatgac agtaggagaa ttgctagaac atggtgacct
    27181 tggtttggga accttggatt ccattgatgg ggaattgatt gtcttggatg gcaaggctta
    27241 tcaggccaaa gggtcaggag accagccaga aattgtggaa gtgtcaccag atgcccttat
    27301 tccttacgct gcagtggtac cgcatcaggc agaggtcatt ttccgccagc gctttgagat
    27361 gacagacaag gaattgaaag aacgaattga gtcttattat gatggggaaa atcttttccg
    27421 ctctatcaag attcgggggg aattttcaca tatgcatgtg cgtatgattc ctaagtcaac
    27481 acccgatacc aagtttgctg atgtcgcaac ccatcaaccg gaatatagtc gtgacaatgt
    27541 tgcggggact attgttggtt tctggacgcc tgagattttc catggggtca gtgtggcagg
    27601 ctaccatctg cacttcatat cagatgattt gaccttcggt ggacatgtca tggattttgt
    27661 catcaaggaa ggcattatcg aggtgggagc agttgaccag ttggaccaac gtttcccagt
    27721 ccaagaccgt caatacttgt ttgctaagtt caatgttgac gagatgaaaa aagatattga
    27781 aaaggcagaa taggagaaga aaatgaccat tcatatcatt attaccatgt tgctgttgct
    27841 agcttttctg ataggaagca tttggtttgc caaaaagaaa taccagatta atctagctgt
    27901 cttgggcttg ggtgcagtcg ctttctttgt ctcttcgcag attttggaaa aactggtgca
    27961 tatcttgatt ttgcatcctc aaaaagacgg tagtattgcc ctcttgcaag atcatccgct
    28021 tatctatatt atctatggcc tagccatggc agcatttttt gaggaaacgg ctcgtcttgt
    28081 tttcttcaaa tggttggaga aaaagagaag tttggaaaag gcagatgcct tggcctatgg
    28141 cctagggcat ggtggcttgg agttgatttt tctaggcctt attagtttac tcaatcttta
    28201 catcgttctt tcggcagttc aaactcagaa tccacaggtt atgcaattac tgtctgaaaa
    28261 tatgttaaaa accattcagt cactttcggt ctggcagatt tatttgcttg gttttgagcg
    28321 aatcttggcg cttggtttcc aattactttt gacagtttgg gtttaccaag ctgttcgcca
    28381 gaagaaatgg atttatctcc tagcagccta tggcttgcat gccttctttg atctggcacc
    28441 atctcttttc caagtaggct ggttgacaaa tccagtcttg gttgaagtga ttctagcact
    28501 ggagctcgtt ctggtcgcct atggaaccaa ggaaatcttt tgtaaaaaat cataaaaagg
    28561 ggggaacctc tttttcttat gcaaaatcca aacaaggtat ttttatggtc gtcaaatgtc
    28621 tctaaaaatg gtataatgga atgaattttg taaaaggaag agtgacatgt ctgtaagaga
    28681 aaaaatgctt gaaatcttag aaggaattga tatccgtttt aaggaaccct tgcatagcta
    28741 tagttataca aaagtaggtg gagaggctga ttatttggtc tttccacgaa atcgttttga
    28801 gttggctcgc gttgtgaaat ttgccaacca agaaaatatc ccttggatgg ttcttggcaa
    28861 tgcaagcaat atcatcgttc gtgatggtgg gattcgtgga tttgtcatct tgtgtgacaa
    28921 gctcaataac gtttctgttg atggctatac cattgaagca gaagctgggg ctaacttgat
    28981 tgaaacaact cgcattgccc tccgtcatag tttaactggc tttgagtttg cttgtggtat
    29041 tccaggaagc gttggcggtg ctgtctttat gaatgcgggt gcctatggtg gcgagattgc
    29101 tcacatcttg cagtcttgta aggtcttgac caaggatgga gaaatcgaaa ccctgtctgc
    29161 taaagacttg gcttttggtt accgccattc agctattcag gagtctggtg cagttgtctt
    29221 gtcagttaaa tttgccctag ctccaggaac ccatcaggtt atcaagcagg aaatggaccg
    29281 cttgacgcac ctacgtgaac tcaagcaacc tttggaatac ccatcttgtg gctcggtctt
    29341 taagcgtcca gtcgggcatt ttgcaggtca gttaatttca gaagctggct tgaaaggcta
    29401 tcgtatcggt ggcgtagaag tgtcagaaaa gcatgcagga tttatgatca atgtcgcaga
    29461 tggaacggcc aaagactacg aggacttgat ccaatcggtt atcgaaaaag tcaaggaaca
    29521 ctcaggtatt acgcttgaaa gagaagtccg gatcttgggt gaaagcctat cggtagcgaa
    29581 gatgtatgca ggtggtttta ctccctgcaa gaggtagtgg ggacctgaca gagccccgat
    29641 cggttaatct atgaaaaaga aggaatttat gccaattgaa aaaaccaatt atcgaattca
    29701 aaaacgtctc taaagttttt gaagacagca acaccaaggt tctcaaagac atcaactttg
    29761 agttggaaga agggaaattc tacacccttc taggtgcatc tggttcgggg aaatcaacta
    29821 tcctaaacat tattgcaggt ttactggatg cgacgacagg agatatcatg ctagacggtg
    29881 ttcgtatcaa tgatattcca accaacaagc gcgacgtaca taccgtcttc caatcctatg
    29941 ccttgttccc acatatgaat gtgtttgaaa atgttgcctt tccacttcgc ttgcgtaaaa
    30001 ttgataagaa agaaattgag cagcgtgtag cggaagttct caagatggtt cagttggaag
    30061 gttatgaaaa acgttccatc cgcaaacttt ctggaggaca acgtcagcgt gtggccatcg
    30121 cccgtgctat catcaaccaa ccccgtgtgg tcttgttgga cgagccttta tcagcgctgg
    30181 acttgaaatt gagaacagac atgcagtacg aattgcgtga attacaacaa cgattgggca
    30241 ttacctttgt ctttgtcact cacgatcagg aagaagctct tgccatgagt gactggattt
    30301 tcgttatgaa tgatggcgag attgtccagt ctggaacccc tgtggacatc tacgatgagc
    30361 caatcaacca ctttgttgcc acctttatcg gggagtcaaa catcttgcca ggtaccatga
    30421 ttgaggacta cttggtcgaa tttaacggca aacgctttga agcggttgat ggtgggatga
    30481 agccaaatga acctgttgag gtcgttattc gtccagagga cttgcgcatt acccttcctg
    30541 aagaaggcaa gctccaagtt aaggtcgata cccagctctt ccgtggggtg cattatgaaa
    30601 ttatcgccta tgacgaactt ggaaatgaat ggatgatcca ctcaacccgt aaggccatcg
    30661 tgggtgagga aatcggtctg gactttgaac cagaagacat ccacatcatg cgtctcaatg
    30721 aaaccgaaga agagttcgat gctcgtatcg aagaatacgt ggaaatcgaa gagcaagaag
    30781 caggtctgat caatgcgatc gaggaggaaa gagatgaaga aaacaagctc taaactcttt
    30841 gtagtgccct acatgctttg gattgccctc tttgtattgg cacccttggt cttgattttc
    30901 ggacaatcct ttttcaacat tgaaggccag tttagtttag aaaattataa atcttacttt
    30961 gcgtcacaaa acttgaccta cctcaaaatg agtttcaact cagtgcttta tgcagggatt
    31021 gtgacctttg taaccttgct tatcagctat ccaacagccc tctttttgac ccgtctcaag
    31081 caccgtcaac tctggctcat gctgattatc cttcctacct ggatcaattt gctccttaaa
    31141 gcctatgctt ttatcgggat ttttggtcaa aatggctcta ttaaccaatt cttggaattt
    31201 atcggaattg gttcacaaca gttgcttttt accgattttt cctttatctt tgtcgcaagc
    31261 tacatcgagc tcccctttat gattttgccg attttcaatg tcttagacga tatggataat
    31321 aatctcatca atgctagtta cgaccttggt gcaactaagt gggagacctt ccgtcatgtc
    31381 atcttccctc tatctatgaa cggtgtgcga agtggggttc agtcggtctt tatcccaagt
    31441 ttgagtctct tcatgctgac ccgtttgatt ggtgggaacc gcgttatcac cttggggacg
    31501 gctattgagc agaattttct aaccaatgac aactatggta tgggttcaac tatcggtgtg
    31561 attctcatcc tgaccatgtt catcaccatg tgggtgacta aggaaaggag agaacgatga
    31621 aaaaatttgc caacctttat ctgggactgg tctttctggt cctctacctg cctatctttt
    31681 acttgattgg ctatgccttt aatgctggtg atgatatgaa tagctttaca ggttttagct
    31741 ggactcactt tgaaaccatg tttggagatg ggagactcat gctgattttg gctcagacat
    31801 ttttcttggc cttcctatca gccttgatag cgaccattat cgggactttt ggtgccattt
    31861 acatctacca gtctcgtaag aaataccaag aagcctttct atcactcaat aatatcctca
    31921 tggttgcgcc tgacgttatg attggtgcta gcttcttgat tctctttacc caactcaagt
    31981 tttcacttgg ctttttgacc gttctatcta gtcatgtggc cttctccatt cctatcgtgg
    32041 tcttgatggt cttgcctcga ctcaaggaaa tgaatggcga catgattcat gcggcctatg
    32101 acttgggagc tagtcaattt cagatgttta aggaaatcat gcttccttac ctgactccgt
    32161 ctatcattgc tggttatttc atggccttca cctattcgtt agatgacttt gccgtgacct
    32221 tctttgtaac aggaaatggc ttttcaaccc tatcagtcga gatttactct cgtgctcgca
    32281 aggggatttc gctagaaatc aatgcccttt ctgctctagt ctttctcttt agtattatcc
    32341 tagttgtagg ttattacttt atctctcgtg agaaggagga gcaagcatga aaaaaatcta
    32401 ttcattttta gcaggaattg cagcgattat ccttgtcttg tggggaattg cgactcattt
    32461 agatagtaaa atcaatagtc gagatagtca aaaattggtt atctataact ggggagacta
    32521 tatcgatcct gaactcttga ctcagtttac agaagaaaca ggaattcaag ttcagtacga
    32581 ggcttttgac tccaacgaag ccatgtacac taagataaag cagggtggaa cgacctacga
    32641 tattgccatt ccaagtgaat acatgattaa caagatgaag gacgaagacc tcttggttcc
    32701 gcttgattat tcaaaaattg aaggaatcga aaatatcgga ccagagtttc tcaaccagtc
    32761 ctttgaccca ggtaataaat tctccatccc ttacttctgg ggaaccttag gaattgtcta
    32821 caacgaaacc atggtagatg aagcgcctga gcattgggat gacctttgga agctggagta
    32881 taagaattct atcatgcttt ttgatggggc gcgtgaggtg ctgggactag gactcaattc
    32941 cctcggctac agcctcaact ccaaggatcc gcagcagttg gaagagacag tggataagct
    33001 ctacaaactg actccaaata tcaaggctat cgttgcggac gagatgaagg gctacatgat
    33061 tcagaataat gttgcaatcg gcgtgacctt ctctggtgaa gccagccaaa tgttagaaaa
    33121 aaatgaaaat ctacgttatg tggtaccgac agaggccagc aatctttggt ttgacaatat
    33181 ggtcattccc aaaacagtta aaaatcaaga ctcagcctat gcctttatca actttatgtt
    33241 gaaacctgaa aatgctctcc aaaatgcgga gtatgtcggc tattcaacac caaacctacc
    33301 agcgaaggaa ttgctcccag aggaaacaaa ggaagataag gccttctatc ccgatgttga
    33361 aaccatgaaa cacctagaag tttatgagaa atttgaccat aaatggacag ggaaatatag
    33421 cgacctcttc ctacagttta aaatgtatcg gaagtaggag ataaacgtaa gaagacgaat
    33481 cagtcaagct ggttcgtttt taaggaatag aagtcagttt ttagagccct atctttttct
    33541 attctagttg tttatttgtt tatttgctta tttgcttgcc tagtagtata ctaagcctat
    33601 actcttcaaa ccacgtcagc gttgccttgc cgtactcaag tacagcttga agctagcttc
    33661 ctagtttgct ttttgatttt tattgagtat taaccttaca gaaagcggca acaaataatg
    33721 aaaatgtcta cttttttcaa aaaaagtttc tggccaacct ttatgattgt taaccaaact
    33781 gctatactat tccatttaaa tgatggcttg gatcgacaat acctaacaac tgagtccata
    33841 tattgggtga taggcacctt tatatttgga aatattctag tagctgtgtt tagtaatatg
    33901 aaaatttggg ataaaaagaa aaatggcagt aagaaaaaat atatcctgaa aaagtaatca
    33961 gagatgtagg gaattggtct aattcaacgg agatcatttc cagttgacgc aagcttaaaa
    34021 aaacgttata ataagaaagt tgagaattga ttttcacttg tcttagtcca gagaaatggc
    34081 ggtgctgcga gccatctaag ctaggaagtc atgctactca atcatacaat tgcataagaa
    34141 caagagaatg acaagttcat tgaatgaagg tggtaccgcg gtttttcgcc cttcgtgata
    34201 tgagcttgtc ttttgatttt tggaggtgtt gatgaaaaca tttcttgtca aacaaaagtt
    34261 tcgtcttgga ggcgaacgct tcgctatcaa ggatgacagg ggagaaattg cctatcaggt
    34321 ggagggatca ttttttaaga ttcccaaaac ttttaccatc tatgatgcgg ctggtgaaca
    34381 agtcagtcag atcagtaaag aaatcttgac cttgcttcct cgttttgaga ttcagcttcg
    34441 ggatggctcg agttttgtca ttcgtaagaa gttgaccttc tggcgagata agtatgagtt
    34501 tgataatcta ggtcttcgta tcgagggcaa tatctgggat ttgaatttca aattgctgga
    34561 tgatcgcgat cagttgattg cggaaattaa gaaggaactc ttccatctga cctctaccta
    34621 taccgtaacg gttcttgaag acgcttatgc agacctagtc atttccctct gtgtcgcgat
    34681 tgactatgtg gaaatgctgg aaagccaatc acattaaaca agtgaataag gagacaatat
    34741 gaaacaacta tctagtgcac aagtacgcca aatgtggctt gatttctggg cgaccaaagg
    34801 tcactcagta gaaccatcag taagtttggt tcctgtaaat gacccaactc ttttgtggat
    34861 caactctggg gtagcaaccc ttaagaaata ctttgacggg accattatcc ctgaaaatcc
    34921 acgtattacc aatgcccaaa aggctatccg taccaacgac atcgaaaacg tagggaagac
    34981 tgcgcgtcac cataccatgt ttgaaatgct ggggaacttc tctatcgggg attacttccg
    35041 tgacgaagct atcacttggg cttatgagct tttgacaagc cctgaatggt ttgatttccc
    35101 tgctgaaaaa ctttacatga cctactatcc agacgataaa gattcttaca accgctggat
    35161 tgaagtggga gtggatccaa gtcacttgat tccaattgag gacaacttct gggaaatcgg
    35221 tgcgggacct tctggaccag atacagaaat cttctttgac cgtggggaag cctttgaccc
    35281 agaaaatatc ggtcttcgcc tgcttgcaga agatattgaa aacgaccgtt atattgaaat
    35341 ctggaacatc gttttgtcac aatttaacgc agaccctgct gttcctcgta gcgaatacaa
    35401 ggaattgcca cataagaaca ttgatacggg cgctggtttg gagcgtttgg tggccgttat
    35461 ccaaggggct aagaccaact ttgaaacgga cctcttcatg ccgattatcc gtgaagtcga
    35521 gaaattgtct ggtaaggttt atgaccaaga tggcgacaac atgagcttca aggttatcgc
    35581 agaccacatt cgttctcttt catttgctat cggtgatggt gcccttccag gaaatgaagg
    35641 tcgtggttat gttcttcgtc gtcttctccg tcgtgcttct atgcatggtc aaaaattggg
    35701 tatcaacgag cctttccttt acaaattggt tccaactgtt ggaaaaatca tggaaagcta
    35761 ctacccagaa gtgcttgaga aacgtgactt tattgagaaa atcgttaaga gcgaagaaga
    35821 atcatttgcc cgtacccttc actcaggtca acactttgcc caaggcattg tggcagactt
    35881 gaaagaaaaa ggtcaatctg tcattgctgg tcaagatgtc tttaaactct atgatactta
    35941 tgggttccca gttgaattga ctgaagaaat cgctgaagaa gctggtatga ctgtagaccg
    36001 tgaaggtttt gaagcagcca tgaaagaaca gcaagaacgc gcgcgtgcgt cagctgtcaa
    36061 gggtggctca atgggtatgc aaaatgaaac tcttcaaaac atcactgtag aaagtgtctt
    36121 caactacaat actagccaat tgtcttctaa attggtagct atcgttgctg acaatgcaga
    36181 agtaggagct gtttcagaag gaactgcctc tcttatcttt gcggaaacgt cattttatgc
    36241 tgaaatgggt ggacaggtag ctgactacgg acaaatcttg gatgagtcag gtaagattgt
    36301 ggctactgtg accaatgttc agaaagcccc aaatggtcaa gcccttcata cagttgaagt
    36361 ccttgcaccg cttgccttga accaagaata taccttggca attgatagca atcgccgtca
    36421 ccgtgtcatg aaaaaccaca ctgcgactca tttgcttcac gctgcccttc acaatatcct
    36481 tggaaaccac gcaacacagg caggatctct taacgaagtt gaattccttc gctttgactt
    36541 tacccacttc caagcagtaa ctgctgagga acttcgtgcg attgaacagc aagttaacga
    36601 gaaaatttgg gaagcacttg aagtgaagac agttgaaacg gatattgaca ctgctaaaga
    36661 aatgggagct atggccctct ttggtgagaa atacggcaag gaagttcgtg tcgtgactat
    36721 cggtgactac tctattgaac tttgtggtgg tactcatgtt gacaacactt ctgagattgg
    36781 tctcttcaaa attgtcaaag aagaaggaat cggttcagga actcgccgta tcttggcagt
    36841 gactggtaag gaagcctttg aagcctatcg tgaacaagag gatgctctta aagctatcgc
    36901 agcaaccttg aaagcacctc aagtcaagga agtacctcac aaggtagaag gacttcaaga
    36961 acaacttcgt caacttcaaa aagaaaatgc tgagttgaaa gaaaaagccg cagctgcagc
    37021 cgcaggcgat atcttcaaag atgttaagga agtcaacggt catcgttaca ttgctagtca
    37081 agtgtctgta tccgatgccg gtgcccttcg tacttttgca gataactgga aacaaaaaga
    37141 ctactctgat cttcttgtcc tagttgccgc tatcggtgac aaagtcaatg tccttgtagc
    37201 aagcaagaca aaagaccttc atgcaggaaa ccttgtcaaa gaattagcac caatcatcga
    37261 tggacgtggt ggtggtaaac cagacatggc catggcagga ggaagcaacc aagctaagat
    37321 ccaagaattg ttggatgcag tagcaggtaa attgtaatca agtaaagatc tatccatttg
    37381 ggtaggtctt tttgtgaata caaaaaagcc aaatccgctt ggacctagct tggttattat
    37441 gagctattag atggtattga ctgcccagac acttacggat ctagctgaga cagggaattg
    37501 tccataacct tcctcatcaa ttgtaacttg accttggtgg ttaccaagta aatctacaaa
    37561 ggtttgatta gtccattctt gaccgacaaa cattgacttg ctgttttctt ggtcatttga
    37621 gataaggact gcgattgggg attgattttc agcacctgaa cgtacccaac cgatacagtt
    37681 agcatggtca aagtagtcat tttgttctcc ataggccaag tcttttcgga tggctaggag
    37741 gcggtcaagg atttctttga aatcttcttg agcatactgg cctgaaatcc catagtagtc
    37801 tccgtaaaag acacatggaa ggccgtcttg gcgtaacaaa atgagggcat aggctgctgg
    37861 cttgaaccat tcttcaacgg tagactcaag ggcttgtcct cgttgggtat cgtggttgtc
    37921 gacaaaagtc acagccttgt caggcttgag ttcaaccagg ctatctgtga aaatgccacg
    37981 aaggtcatag tttgcgccag cttgactggc ttcaaagaga ttctggtgga gacgaacatc
    38041 gacaaggtca aagtgttctt ccgttttttc gagatagtcc agattggctt ccttgtctgg
    38101 gttccaaaat tcaccaaaaa catagaaatc gtcaccgtat ttttccttca tatcgcggat
    38161 gaagttgcgc ataaagaaag agtcaatatg cttaacggca tccaaacgga aaccagctac
    38221 accagtcgtt tccatgaacc aatcagccca gtcatagatg ttttggatga cttcaggatg
    38281 tttaaagtct aggtcggcat acatgaggta gtcgtagttt ccgttttcgt tatcgaccaa
    38341 ttccttgtta gcccagccct tgttgtcccc ttggatcaga taaatcccag atttactgcg
    38401 tttggcatcg tagtctgtac cggtgaagtg gtaccaatgc cagtggaagc cattataggt
    38461 atcttggcga ccatcgaagg taaaactagt ccagccattg atggtgaagg gttctccaag
    38521 ttcaactgta cggtctacag gatcaacttc gataacctga aaggcttccc tgttatcggc
    38581 agcagccttg tggttgagaa ctacatcggc cataggttga attccctgtt ctttaagggc
    38641 ttgaatggct tgaagatagt cttctttgaa accatacttg gtgcggacag tccctttttg
    38701 gttgaactct cctaagtcaa ataagtcata gaccccatag ccgacatctt tttcgttggt
    38761 tgccttgaag gctggtggca tccagacgtg actgatcccc agatgagcta ggtgtggagc
    38821 attttcagcc agacgcgtcc agtgttgacc gtcgtggggc agataccatt caaagtattg
    38881 catgagtgtt tgattttgca tgatgtttcc tcttacttgt caatcttgtt ctttattcta
    38941 tcataaagta tctctcggcg caaacgtttg cgtaagatag aaggaaacta ttttaactac
    39001 ttaaaataaa gtattgattt ttttgtatca aagtgctagt atagcgatgt ataatacaga
    39061 taaagatagg agttgtccca tgattgaatt tcaaaatgtt agtaagttgt atggtgataa
    39121 agaggccttg agtaatctca atttgcagat tgaaaatgga gagattatgg gcttgattgg
    39181 tcataatggg gctggaaaat cgaccaccat aaaatcccta gtcagtatca tttcacccag
    39241 cagtggtcgt attttggtag acggtcagga gttatcggaa aatcgcttgg cgatcaaacg
    39301 aaagattggc tacgtagcag actcgcctga cttattttta cgcttaacgg ccaatgaatt
    39361 ttgggaattg atcgcttcat cctatgatct gactagctct gacttggaga ctagtctagc
    39421 taggctattg aacgtttttg attttgctga aaaccgctat caggttattg aaactctttc
    39481 tcacggaatg cgtcagaaag tctttgtcat tggggcactc ttgtctgctc ctgatatttg
    39541 ggttttggac gaacccttga ctggtttgga tccccaggcc gcctttgatt tgaagcaaat
    39601 gatgaaggaa catgcacaaa aaggcaagac ggtcttgttt tcaactcatg tccttgaggt
    39661 agccgagcaa gtctgtgatc ggattgctat tttgaaaaag gggcatttga tctattgtgg
    39721 tagtgtagag aacttgagga aagaccaccc agaccagttt ttggaaagta tctaccttag
    39781 tcttgctggt agaaaagagg aggttgcgga tgcgtctcaa ggtcattaaa aaattagttg
    39841 atatcaatat cctctattca tctcaagaag ctaatctggc taatctacga aagaagcagg
    39901 ctaagaatcc tgggaaaaaa gtaaatgttt ctgctagagt cctaagttct tacatttttt
    39961 ccagtctctt gatgctcatc tgttttagta atatagccat tcattttcct tttgaggaaa
    40021 tgcctattta ttttagctcg atggttgcta ttttactggt gctggccttt tcaacttctt
    40081 tcactgcctt ttacaatgtc ttttatgaga gtaaggacct ggcctcctat aggccctatg
    40141 cctttaaaga atcagagatt ataatggcca aaggtctgtc tgtcctcttg ccagctctaa
    40201 ctggaattgt accaatccta gcttattttc tagccctcta tattagtcta gctccttctc
    40261 tttggctggg tttgcctttg atgctactgt ccttgacctt attatttgtc tctgttactt
    40321 tagtgacggt agtggcagta catttcttgg ctcagactag ggtcttcaga aagtatcagt
    40381 ctattttttc gaatgtgatg attgggatag gagttctcat acctttaata tttatcttct
    40441 ttcttcagtc gacttttgga agtattgttg acaaagttag agacattcca tttctccttt
    40501 atcctcttca tatcttttac aaaatagcag tggagccttt ttcgacagaa gccttagtgg
    40561 gtctgctcgc ttggatagga ctaactctct tcctgcttta tctgaccaaa aagaaggtcc
    40621 ttcctcgttt ttatgacgtg atcctgctta acagtgagga gaaggtcaaa aaagaacgtc
    40681 gcagcaagga gaggatttca actactaaaa agggcttttt ccgtatggtt ttacgctacc
    40741 acctcaccct cttgggacag gggactggtg tgattacagt gctttttaca agtgctttcc
    40801 ttccttatct catgatgatc agtctgattt ccaaaatccg agattctcag atagttccag
    40861 acattcatcc tccatactgg ttacccttgt tttttgtagg agtgtttata gcagttgtca
    40921 ataacaatat caccagcctg cattcaattg ccttgtcctt ggagagggaa aatgttgatt
    40981 ttctgaagag tttacccttt gactttgctc gttatgtgaa agtgaaattt tggattatct
    41041 ttgctgttca gtccttttta ccagttctga ctttgctcgg tctttctcta tatctaggct
    41101 tgcccatcct ttcgatgatt taccttcttg tagtctggat cattgccagt gtcatccttt
    41161 cttgccacca ttactttaag gacgttaaaa atctgtcaac caattggagt agcattacgg
    41221 acctggtgaa tcgttcaaat ggcatagtcg ccatagtttt attgtttatt tatagtgcaa
    41281 tcctgatggc ccttgtaatt gggagcatat tcttggttca gtctctctcc cctatccttg
    41341 ccatcaactt gggagtagga gctcttatcg tcttgcttgc tcttgctatt tttggctatc
    41401 attattacct gtcacgcata ttggcagaaa tagaaaaaag atgagatagt tggttgcttg
    41461 cttgataaat tcaattcgac aaacgctttt atagtttgtt agaatgtagt tgtaaatgat
    41521 taagattggt aatcaaaaat atagggagga atgttttgaa taagaaatat aatatagttc
    41581 tattattgtt gtttatagtt tatttattgg gatatttttc aatttcaaaa acgttaattc
    41641 ctataatgtg tgtgatccaa gtatttttga tagaacatat atttagagtt cgaaatagaa
    41701 tgatgcaaat aggtgaaatt ttaattattg ttgcttctat aatattattt attgatagta
    41761 tattgagttt gtaacaaaag gcttttctat aaaatcaaat tttccagata cctattgaag
    41821 cagatttatt tcttcatctt tcttctacta cctttgtcac taaatttgac agacacatat
    41881 tgctgattca acctctctac ctataatctc acagttaacc tgaggctagt ttcatagttt
    41941 gctatttgat tttcgttgat aaaaagaaat gctcctccaa gatggaagag cattttttat
    42001 tgtgattctt acacatttac ttcctagttt tgcaggaagt ctagtatacc attttttaaa
    42061 agaagagtaa aaaagcaagg gtagtttctt ttttgagaat tgtctaaaag tttgatataa
    42121 tggtagttat gaatagaata agagtcagca aaagggttga aaagaagctt gctaaggggc
    42181 tagttttact agaagccagt gatcttgaga atgtcaatct taaggatcag gaagtagagg
    42241 tgcagggtca ggaaggaaac tttcttggga ctgcctacct ttctcagcaa aacaagggct
    42301 tgggctggtt tgtcagcaaa gacaaggtgg ccttcaatca agctttcttt gaaacgttgt
    42361 ttagaaaagc caaagaaaag agaaacgcct actatcaaga tgatttgaca actgcctttc
    42421 gtctctttaa tcaagaggga gatggctttg ggggtctgac agtggacctt tatggcgact
    42481 acgccgtctt ttcttggtat aactcttatg tttatcagat tcgtcagact atatcagaag
    42541 cctttagaca ggttttccct gaggttttag gagcttatga gaaaatccgc tttaagggtt
    42601 tggactatga atctgcccat gtttatggtc aagaagcacc tgactttttc actgttttag
    42661 aaaatggtgt cctgtatcaa gtctttatga atgatggctt gatgacagga attttcctag
    42721 accagcatga ggttcgcggt agtttagttg acggcttggc tatgggtaaa tccttactca
    42781 atatgttttc ctacacagcg gctttttcag tagctgcggc catgggagga gctagccaga
    42841 caacttctgt tgatctagcc aaacgttcac gagaattgtc tcaagcgcat tttcaggcaa
    42901 atgggctcag cacagacgag catcgtttta tagtcatgga tgtctttgag tatttcaaat
    42961 atgccaaacg caaagacttg acctacgatg tgattgtcct agatccgcct agctttgctc
    43021 ggaataaaaa acaaactttc tctgtggcca aggattatca caagttgatt tcccagagtc
    43081 ttgagatttt aaatccggga gggattatca ttgccagtac caatgctgcc aatgtttccc
    43141 gtcagaaatt tacagaacaa attgataaag gttttgcagg aagaagttac cagattttaa
    43201 acaaatatgg tcttccagca gattttgcct ataataaaaa agatgaaagt agtaattacc
    43261 tcaaggtgat tagtatgaag gttagtaaat gaaattaatc gtttcagtaa tgccaagaag
    43321 tttagaggag gctcaggctc tggatgccac gaggtacttg gatgccgaca tcattgaatg
    43381 gcgtgccgac tatctgccta aagaagcgat tttgcaggta gctccagcca tttttgaaaa
    43441 attcgcaggc cgtgagttgg ttttcacgct acgaactcgc tccgaaggtg gagaaatcga
    43501 cctttctcca gaagagtata tccatctaat caaggaagtt gcgcaactct atcaaccaga
    43561 ctatattgat tttgagtact atagctacaa ggatgttttt gaggaaatgc tggacttccc
    43621 aaatcttgtt ttgagttacc ataatttcca agaaacacct gagaacatga tggaaatctt
    43681 gtcagagttg acgatcctaa atccaaaact tgttaaggtt gcggtgatgg ctcacacgga
    43741 gcaggatgtc ttagacttga tgaactatac acgaggcttt aaaaccctca atcctgaaca
    43801 ggaatatgtg accatttcta tgggtaaggt gggcaaggtc tctcgtatca ctgcggatgt
    43861 gactggttcg agttggtctt ttgccagtct ggatgaggtt agtgcccctg ggcagatttc
    43921 tctagctagc atgaaaaaaa tcagggagat tttggatgaa gcttgatggc tatacacgtt
    43981 tagctgcagt tgttgccaat cctattaagc attctatttc tcccttcatc cacaatagag
    44041 cctttgaggc gacagctacc aacggtgctt atgtggcttg ggagattgaa gcgagtgact
    44101 tggcagaaac agtggccaat attcgtcgct accagatgtt tggcatcaat ctgtccatgc
    44161 cctataagga gcaggtgatt ccttatttgg atgagctaag cgatgaagcg cgcttgattg
    44221 gtgcggttaa tacggttgtc aatgagaatg gcaatttaat tggatataat acagatggca
    44281 agggattttt taagtgcttg ccttctttta caatttcagg taaaaagatg accctgctgg
    44341 gtgcaggtgg tgcggctaaa tcaatcttgg cacaggctat tttggatggc gtcagtcaga
    44401 tttcggtctt tgttcgttcc gtttctatgg aaaaaacaag accttaccta gacaagttac
    44461 aggagcagac aggctttaaa gtggatttgt gtgctttaga atatgtttct gaactgcaag
    44521 caaggattgc cgagtcggat ttgctagtta atgccaccag tgtgggcatg gatggccaat
    44581 cctctcctgt tcctgaaaac atagtcttac cagaaactct tttagttgca gatatcatat
    44641 accaaccctt tgaaacaccg tttttgaaat gggctagaag tcagggcaat ccagcagtca
    44701 atggtctggg aatgttgctc tatcaagctg cagaagcttt tcaactgtgg acaggcaagg
    44761 aaatgccgac agaagagatt tggcagtctt taacagaaaa ataccaataa agaaagggag
    44821 actctcctat gaaaatcaga atcgatattc ctcatcatcc ttatgatatt cagattgaaa
    44881 aaggttgtat ggcccaggct ggtcagtggt tgcgagaact ctggcaaccg caaaaggtag
    44941 tcattgtgac agataaccat gtagcctctc tctatgcaga gaaggtcaag ctcagcctag
    45001 aagatgctgg ttttcaggta gctgtttttg atttcttaga aggtgaagaa agaaagaatt
    45061 taactactgt tcagaaagtc tatgaatttc tagtcaagca aggtctgact cgtagcgatg
    45121 gaatcgttgc tcttggtggt ggcgttgttg gggacctggc tggctttgta gcctctacct
    45181 atatgcgggg tattcacttt gttcagattc cgactagttt gacagctcag gttgattctt
    45241 ctatcggtgg aaagacaggc gttaacacac catttgctaa aaatatggtg gggacctttg
    45301 cccaaccaga tggggttctg attgatccac ttgttcttga aaccctcgga aaaagagagt
    45361 tgattgaagg gatgggtgaa gttatcaagt atggcttgat tgaggatcca gaactgtggg
    45421 ctctcttgac gggactgaat ggttctgttg agagtatttt ggaacatgca gagaccttga
    45481 ttgaacattc ttgtcaggtg aagcgcaaga tggtggttga agatgagttg gacaatggta
    45541 ttcgtcttta cctcaatttt ggccacacta ttggccatgc catcgaagcg actgccggtt
    45601 atggcaaggt catgcatgga gaggctgttg ccatgggaat ggtacagatt tccaagattg
    45661 ctgaggaaaa aggcctcatg ccagctggca ttacccaatc tatcacagag atgtgtcaga
    45721 aattcggctt gcctgttgac tatgaaaatt gggaagttga caagctttat caggctctta
    45781 ctcatgacaa gaaagcgcgt ggcaacacct tgaaattggt cttggtgcca gagcttggtt
    45841 cagcgatcat tcacccagtt tctctggaag agatgaaaga ctacttggta aaataaggag
    45901 agtgtatgag atatttaact gcaggagaat cacacggccc ccgtctaaca gctattattg
    45961 atggaattcc agctggactt ccattgacag ctgaggatat caatgaggac cttagacgcc
    46021 gtcagggtgg ctacggtcgt ggtggtcgta tgaagattga gaatgaccag gttgtcttta
    46081 cttcgggcgt tcgccacggg aagacgacag gggcgcctat tactatggat gtcatcaata
    46141 aggaccacca gaaatggctg gacatcatgt ctgcggagga cattgaagac cgtcttaaaa
    46201 gcaagcggaa aattactcat cctcgcccag gtcatgccga tttggttggg gggattaagt
    46261 accgttttga tgatttgcga aattctttgg agcgttcatc agctcgtgaa accaccatgc
    46321 gggtggcagt tggtgcagta gccaaacgcc tcttggctga gttggatatg gagattgcca
    46381 accatgtcgt ggtctttggt ggcaaggaaa tcgatgttcc tgaaaatctg acagtcgctg
    46441 aaattaagca aagagctgcc cagtctgaag tttctattgt caaccaagaa cgagaacagg
    46501 aaatcaagga ctatattgac caaatcaaac gtgatggtga taccatcggt ggggttgtgg
    46561 agacagtcgt cggaggcgtt ccagttggtc ttggttccta tgtccaatgg gatagaaaat
    46621 tggatgcaag attggctcaa gctgttgtct ctatcaatgc ctttaaaggg gtggaatttg
    46681 gtcttggctt tgaggctggt tatcgtaaag gcagccaagt tatggatgaa attctctggt
    46741 ctaaagaaga cggttatact cgccgtacca ataatctagg tggttttgaa ggtggtatga
    46801 ctaatgggca acccatcgtt gttcgtgggg tcatgaaacc cattcctact ctttataaac
    46861 ctcttatgag tgtggatatc gaaacccacg aaccttacaa ggcaaccgtg gagagaagtg
    46921 atccgactgc tcttccagct gcaggaatgg tcatggaagc agttgtagca acggttctgg
    46981 cgcaagaaat cctcgaaaaa ttctcatcag ataatcttga ggaactaaaa gaagcggtag
    47041 ccaaacaccg agactataca aagaactatt aaggagttcc tatggcaaaa acaatctata
    47101 tcgcaggtct tgggttgatt ggagcctcta tggcacttgg tatcaaacgc gatcatccag
    47161 attatgaaat tttaggttat aatcgtagtc aagcttcgag agatatcgcc ttgaaagaag
    47221 gcatgattga ccgtgcaacg gatgattttg ctagttttgc tcctttggca gatgtcatta
    47281 tcctcagctt gccaatcaaa caaactattg ctttcattaa ggagttggcc aatttggatt
    47341 tgcgagaagg cgttattatt tcagatgctg gttcgaccaa gtcaaccatt gtggatgcgg
    47401 cggagcagta tttggctggc aagtctgttc gctttgtcgg ggcccatccc atggctggta
    47461 gtcacaagac aggggctgct tcggcagatg tcaatctttt tgaaaatgcc tattatatct
    47521 ttacaccttc aagcctgaca agtcaggaca cgcttaagga aatgaaggat ctgctttcag
    47581 gtcttcatgc tcgttttatc gagattgatg ccaaggagca tgatcgtgtc acttctcaga
    47641 ttagccattt tcctcatatt ttggcttcta gtctcatgga gcagactgcg gtctatgctc
    47701 aagagcatga gatggcaagg cgctttgcgg caggtggttt tcgagatatg acccgaattg
    47761 cggaaagcga gccaggaatg tggacctcca ttctcttgtc caatagcgag atcattctgg
    47821 atagaattga ggatttcaag gaacgtttgg aagcgattgg tcaggccatt agtaagggag
    47881 atgaagagca aatttggaac ttttttaacc aagcgcgtga acaacgccag accatggaaa
    47941 tccataagcg tggtggtgtg gatagctctt acgacctcta tgttgacgtt cctgatgaag
    48001 aagatgtcat cctgcggatt ttggaactgc tacgtggaac ttccttggtt aatatccaca
    48061 tcaacgagga aaatcgtgag gatattcacg gaatcctaca aatttcattt aaaaatgctc
    48121 aagacttgga aagagctgag catctcataa cagaaaatac tgactataca gtcgtcatca
    48181 aataaggaga agaacatgtc aaatatttac gatagtgcaa acgaactcag tcgcggtcta
    48241 cgcggattac cagaatacaa ggctgttaaa gcagctaaag atgcgattgc agcagatgct
    48301 gaggcaagca aaatctttac agattatctt gcctttcaag aggaaattca aaaactagca
    48361 cagacaggtc aaatgccaga tgcgtccttc caagctaaga tggaaggctt tggtaaacag
    48421 attcaaggaa atagcctctt gtcagaattc tttaccaagc aacaacaatt ggccatttac
    48481 ctttctgaca ttgaaaaaat tgtttttgaa ccagtttcag aattgctgaa ataagaaaag
    48541 aactatccta aagtcaggaa tttttaagga atttctggct ttttatgata aaataggtaa
    48601 aagtattgca agtatgaggt ccagtatgaa actaaaaaca aacattcgcc atttacatgg
    48661 tagtatccgc gtcccaggtg acaagtctat cagccaccgt tccattatct ttggaagttt
    48721 ggctgagggt gagaccaagg tttatgatat tctgcgaggc gaagacgttc tttcgaccat
    48781 gcaggttttt cgtgaccttg gtgttgaaat tgaggataaa gatggggtta ttaccattca
    48841 aggtgtaggc atggctggct taaaagcgcc gcaaaatgcc cttaatatgg gaaattctgg
    48901 cacctcgatt cgcctgattt caggtgtcct tgctggtgca gatttcgaag tagagatgtt
    48961 tggagatgat agtctttcca aacgtcctat ggaccgtgtg acccttccac tgaaaaaaat
    49021 gggcgtcagc atttcagggc aaactgaacg agacttgcct ccccttcgct taaaagggac
    49081 gaaaaaccta agccctattc attatgagtt gccaattgcc tctgcccaag tcaagtcagc
    49141 cttgatgttt gcagccttac aagctaaggg ggagtcagtt attatcgaaa aagaatacac
    49201 ccgtaatcat actgaagata tgttgcaaca atttggtggt catttaagtg tggatggtaa
    49261 gaaaatcaca gtccaagggc cacaaaaatt gacaggacag aaggtggtcg taccaggaga
    49321 tatttccagt gcagcctttt ggttagtcgc aggtttgatt gctccaaatt ctcgtctagt
    49381 gctgcagaat gtggggatca acgaaactcg caccggtatt attgatgtca ttcgtgccat
    49441 gggtggaaaa ttggaaataa ctgaaatcga tccagtcgct aaatctgcaa ccttgattgt
    49501 tgagtcttct gacttgaaag gaacagagat ttgtggcgct ttgattccac gtttgattga
    49561 tgaattgcct attattgccc tacttgcgac ccaagcccaa ggtgtaacag ttattaaaga
    49621 tgctgaggag ctcaaggtca aggaaacaga ccgtattcag gttgtggcag acgccttaaa
    49681 tagtatggga gcagatatta ctcctacggc agatgggatg attatcaaag gaaaatcagc
    49741 tcttcacggt gctagagtca atacgtttgg tgaccaccgt atcggcatga tgacagctat
    49801 cgcagcccta ttggttgcag atggagaggt ggagcttgac cgtgcagaag ccatcaatac
    49861 cagctatcct agtttctttg atgatttgga gagcttgatt catggctaag gtgttattag
    49921 ggtttatggg ggctggaaaa tcaactattg caagaggctt ggaccctaat taccttgata
    49981 tggatgctct gattgagaag cgcctaggta tgtccattgc gaattttttc gctgaaaagg
    50041 gagaatcagc ctttcgtcag gtagaatcag aagtcctagc tgatttacta caaacagacc
    50101 aagtcgtgtc aactggagga ggagtggtta tttctcagag aaatcgtgac ttactcaaga
    50161 ctaatacaga taacatctac ctgaaagcag attttgaaac cctctaccta cgtatcgtag
    50221 ctgataagga caatcagcga ccgctttttc taaataatag caaggaagaa ctagtagcta
    50281 tttttcaaga aagacaggct tggtatgagg aagtggctag tcgggttttg gatgtgacca
    50341 agctaagccc agaggaaatt atagaggaac taagatgaaa attgcttatc taggtcccaa
    50401 aggatcattt tcacaccacg ttgtgcagac agcttttcct catgaggaat tgcaggcttt
    50461 tgccaacatt acagatgtta tcaaggctta tgagcaagga ttagtggact attctgtggt
    50521 gccagttgaa aattctattg agggtagtgt tcatgaaacc ttggactatc tttttcatca
    50581 ggctcacatc caagcagtag cagaaatcgt tcagcctatt catcagcagt tgatggtggt
    50641 tccaggccat actaagattg aaaagatttt ttcacatcca caggccttgg ctcaaggaaa
    50701 gaaattcatc gatgaacaat atccagaggc tcaaatcgag gtaacagcta gtacagctta
    50761 tgcggcccgt tttatttccg aacatccaga ccagcccttt gcagcagttg cacctagaag
    50821 ttctgctgaa gaatatggat tggaactgat tgccgaggat attcaggaaa tggaagccaa
    50881 tttcacacgt ttctgggttc taggagctga aaagcctagt attcccttgc aagcacaaac
    50941 tgaaaagatg agtttggcct tgacattacc tgacaacctt ccaggtgcac tttataaggc
    51001 cctgtcgacc tttgcttggc gaggaattga cttgacaaaa attgaaagtc gtccactcaa
    51061 gacagcactg ggtgaatact ttttcattat cgatgtggat tataccgata aggacttggt
    51121 ccactttgcc caaaaagaat tagaagcgat tggaatccag tataaaattc tgggtgccta
    51181 tcctatttat ccaatatcag accatggaaa ggagagaaga tgagtaaaga aaatccctta
    51241 agtcatcatg agcagttgcg ttatgattat ttgctaaaaa atattcacta cctcaatgag
    51301 agagaaaaaa atgagtttgc ctatttgcaa gaaaagctaa ctcttgctag gagaaatagt
    51361 agctctagct tggaacaaga aagagaagag caggttgact taccaagtta tgcgaaccgg
    51421 agtcgctcac aatccaaatc acaagcactc tcttcccctc caaaaaagaa aagacggaag
    51481 ctccgtctta aacgaatttt tatggtgatt ttttcacttt tggtctgtgt ggctttggcc
    51541 atggtattca tgtttttgcg tggttaccaa gatgctagcg caaagaaaac tgctgatgcc
    51601 cgggcagctc aagtagaagt ctttaatggt caggacacta gagatggagt taatatttta
    51661 atcatgggta ctgatggtcg aatcggccag aacagtgttg agacacgaac tgactctatt
    51721 atggtattaa atgtcggggg ctcagataag aaaatgaagc tagtcagttt catgcgtgat
    51781 aatttggtct atatagatgg ttatagtcaa gtgattaacg gtagaaaaca gacagataac
    51841 aagttaaacg tagcctacga gttaggagaa caagaggggc aaaaaggggc agaaatggtt
    51901 cgccaagtct tgaaagataa ttttgacttg gacattaagt actacgcctt ggttgatttc
    51961 caggcctttg ccacagcgat tgacacactt ttccctgatg gggtgacgat tgatgctcaa
    52021 ttttcaacat tgaatgggcg tcccctaaca gaagctacag tcggagatga tttatacgct
    52081 accgagactg agtctccaac ccaaaccatt aaagtcggaa aacagcagat gaatggctcg
    52141 accctgctca attatgctcg tttccgtgat gatgatgagg cggattacgg ccgtacaaaa
    52201 agacagcaac aagttttaac agcaatttta gagcaaatta aagatcccac taaacttttc
    52261 actggttctg aagctcttgg aaaggttttt gctatgacct caaccaacgt accctatact
    52321 ttcctcctaa caaacggttt atctgttttg gatggagcaa aaaatggtat tgaaaaattg
    52381 acgattccag aactgggtga ctgggtagat gcctatgatg tttatggagg cttgggcttg
    52441 ctggttgatc aaaacaaata tcaaaccaag ctcgctcaaa tgggcttgag ataagataat
    52501 actcaatgaa aatcaaagtg caaactagga agctagccgc aggctgctaa aaacacagtt
    52561 ttgaggttat agataagact gacgaagtca gttacctata cctacggcaa ggtgaagctg
    52621 acgtgctttg aagagatttt cgaagagtat aagacagaaa aatcaaagtt tgatagctat
    52681 ttggatagca gtcaggcttt gattttttac agtctgcaat agattttcac cccttgtttg
    52741 tggtataatg aaacgatacg atagaaagaa taatgaacaa tatgactgat ttaaaagcaa
    52801 ttcaggctcg tagtctggag atggctgaat attttgtggc cttttgtaaa gaacatgatt
    52861 tgctctgtta tctctgtggc ggaggcgcta ttggtaccct tcgaaacaag ggatttattc
    52921 cttgggacga cgacctagac ttttttatgc ctcgtaaaga ttatgagaaa ttagcagaat
    52981 tatggcctcg ttatgcagat gaacgttatt tcttgtcaaa gagttacaag gattttgttg
    53041 atcgtaatct ttttattacc attcgtgaca aggaaaccac ctgtatcaag ccttatcagc
    53101 aggatttgga tttgccacat ggtctggcct tggatgtttt gcctttggat tattatccga
    53161 aagatccagc tgagcggaaa aaacaggttc gttgggcctt gatttattca ctcttttgtg
    53221 cgcaaactat tccagaaaag catggtgctc tcatgaaatg gggaagtcgc attttactgg
    53281 gtttgactcc aaaatctctc cgttatcgca tctggaaaaa agctgagaaa gaaatgacta
    53341 agtatgattt ggctgattgt gatggcatta cagaattatg ctcaggtcct ggctacatga
    53401 gaaacaagta cccaatcaca tcttttgaag acaatctttt cttgccattt gagggaacag
    53461 agatgcctat tccaatcggc tatgatgtct atctcagaac tgcttttggg gattatatga
    53521 cgcctccacc agcagacaag caggtaccgc atcatgatgc tgtcatcgct gatatggata
    53581 agtcttatac agaatacaag ggagaatatg gtggctaaga aaaaaatctt attttttatg
    53641 tggtcttttt ctcttggagg tggtgcagag aagattctat caaccattgt ttcaaatctg
    53701 gatccagaaa agtatgatat tgatattctt gaaatggagc actttgacaa gggatatgaa
    53761 tctgttccaa agcatgtacg cattttaaaa tcccttcaag attatcgcca aaccagatgg
    53821 ttacgagctt ttttgtggag aatgagaatt tattttccaa gactggctcg tcgtttgctt
    53881 gtaaaagatg attatgatgt tgaagtttct tttaccatta tgaatccacc actgttgttc
    53941 tctaaaagaa gagaagtcaa gaagatatct tggattcatg gaagtattga agaacttctt
    54001 aaggatagct ctaaaagaga atcacataga agccagttgg atgctgcgaa tacaattgta
    54061 gggatttcaa aaaagaccag caattctatc aaggaagttt atccagatta tgcttctaaa
    54121 ttacagacaa tctacaatgg atatgatttt cagactattc tagaaaaatc tcaagagaag
    54181 atcgatatcg agattgctcc tcaaagtatc tgtactatcg gacggattga ggaaaataag
    54241 ggttctgacc gtgtagtgga agtgatacga ttattacacc aagagggaaa aaactatcat
    54301 ctctatttta tcggggctgg tgatatggaa gaggaactga aaaaacgagt caaagagtat
    54361 gggattgagg actatgtaca tttccttggt tatcaaaaaa atccttatca gtatttatct
    54421 cagacgaaag ttctcttgtc tatgtctaaa caagaaggtt ttcctggagt gtatgtggag
    54481 gccttgagtc tgggactccc ttttatctct acggacgttg gaggggctga ggaattatcc
    54541 caagaaggac gatttggaca aatcattgag agcaatcaag aggcagctca ggcgattact
    54601 aattacatga cttctgcctc aaactttgat gtcgatgagg ctagccaatt cattcaacaa
    54661 tttacaatta caaaacaaat cgaacaagta gaaaaactat tagaggagta gcatggaaac
    54721 tgcattaatt agtgtgattg tgccagtcta taatgtggcg cagtacctag aaaaatcgat
    54781 agcttccatt cagaagcaga tctatcaaaa tctggaaatt attcttgttg atgatggtgc
    54841 aacagatgaa agtggtcgct tgtgtgactc aatcgctgaa caagatgaca gggtgtcagt
    54901 gcttcataaa aagaacgaag gattgtcgca agcacgaaat gatgggatga agcaggctca
    54961 cggggattat ctgattttta ttgactcaga tgattatatc catccagaaa tgattcagag
    55021 cttatatgag caattagttc aagaagatgc ggatgtttca agctgtggtg tcatgaatgt
    55081 ctatgctaat gatgaaagcc cacagtcagc caatcaggat gactattttg tctgtgattc
    55141 tcaaacattt ctaaaggaat acctcatagg tgaaaaaata cctgggacga tttgcaataa
    55201 gctaatcaag agacagattg caactgccct atcctttcct aaggggttga tttacgaaga
    55261 tgcctattac cattttgatt taatcaagtt ggccaagaag tatgtggtta atactaaacc
    55321 ctattattac tatttccata gaggggatag tattacgacc aaaccctatg cagagaagga
    55381 tttagcctat attgatatct accaaaagtt ttataatgaa gttgtgaaaa actatcctga
    55441 cttgaaagag gtcgcttttt tcagattggc ctatgcccac ttctttattc tggataagat
    55501 gttgctagat gatcagtata aacagtttga agcctattct cagattcatc gttttttaaa
    55561 aggccatgcc tttgctattt ctaggaatcc aattttccgt aaggggagaa gaattagtgc
    55621 tttggcccta ttcataaata tttccttata tcgattctta ttactgaaaa atattgaaaa
    55681 atctaaaaaa ttacattaga acgggggtga ccaagtgatt gatgggaaac gattattatt
    55741 tagtttgacc atagtcagtt atgccttgac gctagtaagt ggaattgtgt atctgtttaa
    55801 taataataat gttagcttac tttctacttt attgttcttg ttggttagta gcttaattgc
    55861 ttgttggaat gatatcaagt attacttaat ccattttatt ttctatttaa ccatttttgt
    55921 atttctggta tcaagaccga ccattgatta ttttagggat ggtgctttgg atacctatca
    55981 tccaatagcc tatcgttttg cctttatagt tgtcatggtt tcgattctgg gcttgaccac
    56041 aggaggcatt ctggctcgtt acttcatagc taggaagaaa ataaaagtag caaatatagg
    56101 aaattctcta aaagaggttt atatcaagcg gttacgcttt gtatcactag gagtttttct
    56161 tctaacctat cctttctatt tcattcggtt atttgaacgg ctcttgtatc gtttgcagac
    56221 ttcctactat gcctactatg caaattttga aagtaaactg ccttatttta cctacatttt
    56281 gtctaccttt acggtctatg caatgtgtat gtatctggca accaagccaa agaaattgca
    56341 ggccacagca gtgcttgtct cctttattgc agctaatact attcatttgg caattgggac
    56401 acgaaatccc tttattttaa gtattttatt tgcttttgtt tattacttta tgcgggagca
    56461 aactgaaaaa ggaaaatgga ttgggtttaa agaaaagtta gcgatttttg taggttctcc
    56521 tattctcatg ttagcgatgg gagtactcaa ttatgtacgg gataatgtcc aagtttccca
    56581 tacaggtttc tgggatatct tacttgactt tatctataaa caagggacta gttttggtgt
    56641 tctggctcga ggttttctat ttaacagtag cctcccttac cgagatttcc gtaattttac
    56701 ttttggtcct gttcttgatt attttgcaag ggggagtttg ggagccattt tcggaggaaa
    56761 agcctttgaa catacaacca atagtgtgga actagctatt gatagtaata gttatgccca
    56821 caatctatcc tatcttgtct tgaacaagga atacctgaaa gggcatggta tcggaagtag
    56881 ttatatcatg gagttgtata ccgactatgg tatgattgga gtctttctgc ttagtttctt
    56941 actcggcgta ttatttatag ccatgctgca agtagcctat cgctcaagga caatcctatt
    57001 tgctttatcc ctactcatct tgaataatct attctttatg ccaagaagca gcttttcaga
    57061 aagtttcttc aatttattta caatgcaatt ctggggaatt gttcttgtga ttatatttat
    57121 agcaaaaatg cttacaaagg aaaactagta tctactaaac aaaggagaaa aaaatcatgt
    57181 ttgaacatta ttcagtagct gatttgtttg caaatcttta taaaaagcga aaagcaaata
    57241 ttttagctct catcgcttta tttgctctca ttgctgtacc atttacaatt aaagcagtta
    57301 ggaataaaaa cactgtcaaa gatacaacaa gttattcaac ttatcttatc tataaaatca
    57361 ctcctccaaa agagtcggcc aaaacgattt tgaatcatca aattggtggt tatagtgatt
    57421 tttatgggaa attgattgat ggtaatttga atggagctta tcttttcaat gatgtagaac
    57481 ccagtgagtt gaaaaaaatt gccagtgaat tagacacgac agaaacaacc ttgaaaaatt
    57541 caacgaatga ctattggtgg aaaaaattga ccgtctacta tatgattgac gatgcagggg
    57601 ttggtgtgaa aattttgaca tcaagtaaag atgccaatga cttgttagag aaaaaaattg
    57661 atgggttgat tgagaaattt aaacatgcct atgcaaatgt gaaaattgaa aaactggaaa
    57721 ccatcaactc taaagaattg aacgcaaatg gtgaaacagc gcttggctta aatgtgaaaa
    57781 atctgattct tcgtttagtt gttattggag tggtttgtgt gattttggtt gtgatgggaa
    57841 atgtgttagt ttatctcttt aatccaacaa tcaatagagt aggtgatttt tctcagtatc
    57901 aaattgattt tgtaacagag attacaacaa ttgctaacct agcagatgtt ttgtcataca
    57961 aaaatactgg acaggaattg accatcgtta gctcaaataa agctatccta gataaattga
    58021 aacagagtca agaagcttta aaaggaatgc attttgtaga tttacaggat gtatcatctc
    58081 ttttggaaag agatacagtc cttcttgttg aagagtacgg agtgactcgt tataagaaat
    58141 ttgagcaaag tcttcaaatt ctcagaaact taaatcgttc tatcctcggt gtagcaacct
    58201 ttaaattata agtattctga tgtataaggt cttcaaagtc ggctaagagc cgattttgaa
    58261 ggctttttct atctgtctgc agaaattttc ttttgataaa atcgtaaaaa tctagtataa
    58321 tagatagaac tgaaagtatg aggttactag caatgaaaat gaaacaaatt agtgatacaa
    58381 ctttaaaaat cacgatatct ttagaggatt tgatggatcg tggaatggag attgctgact
    58441 ttctcgttcc tcaagaaaaa acagaagagt tcttttatgc tatcttggat gagctagaga
    58501 tgcctgatag ctttctggat acaggcatgt tgagcttccg tgtgactcca aaacctgata
    58561 aggtagatgt ctttgtgacc aagtcaaaga ttgaccaaaa tctagatttt gaagacttat
    58621 cggatttgcc agatatggaa gaattggctc aaatgtctcc agatgaattt atcaaaaccc
    58681 tggaaaaaag catcgcagac aaaaccaagg atgatatcga agccattcaa tctcttgagc
    58741 aagttgaagc caaggaagaa gaacaagagc aggctgaaca agaagctgag agtaagaaag
    58801 aaccttacat ctactacatc ctttcttttg ctaagttggc tgacttggta gcttttgcca
    58861 agacagtgac ttttgaaatg gaaacttctg aactctacaa aatgaacgag cgctattatt
    58921 tgaccatttt agtggatatt gaaaatcatc caagcccata tccagcttgg ctgttggccc
    58981 gtatgcgcga gtttgcagag gatagtgata tcagtcgctc agtcttacaa gagtatggtc
    59041 aagttttgat gagtcacgat gcagtgctca atctgcaaaa aatcggctaa tcttttctgg
    59101 aaagctattt tcagatttta agaagagcga atcgtctgat tcgttttttc tttttatact
    59161 gaaatagtga tttactataa taggaatttt cacaaaattc tgttataatg gctatattag
    59221 aaaatttcga ggagataaag atgacagtta aaattgcttt actaggattt ggtaccgttg
    59281 caagtggtgt gcctttcctc ctaaaggaaa atggaggaaa aatcaatcaa tcagcacatt
    59341 cagatatcaa agttgctaag gtattggtca aggatgaaga tgaaaaaaat cgcttgcttg
    59401 cagcagggaa tgactttaac tttgtaacca atgtggatga tattttatca gaccaggata
    59461 ttactatcgt agtggaattg atggggcgta ttgagcctgc taaaaccttt atcactcgtg
    59521 ccttggaagc tggaaaacac gttgttactg ctaacaagga ccttttagct gtccatggcg
    59581 cagaattgct agaaatcgct caagctaaca aggtagcact ttactacgaa gcagcagttg
    59641 ctggtgggat tccaattctt cgtactttag caaattcctt ggcttctgat aaaattacgc
    59701 gcgtgcttgg agtagtcaac ggaacttcca acttcatggt gaccaagatg gtggaagaag
    59761 gctggtctta cgatgatgct cttgcggaag cacaacgtct aggatttgca gaaagcgatc
    59821 cgacgaatga cgtagatggg attgatgcag cctacaagat ggttattttg agccaatttg
    59881 cctttggcat gaagattgcc tttgatgatg tagtccacaa gggaatccgc aatatcacac
    59941 cagaagacgt agctgtagct caagagcttg gttacgtagt gaaattggtt ggttctattg
    60001 aggaaacttc ttcaggtatt gctgcagaag tgactccaac cttcctacct aaagcgcacc
    60061 cacttgctag tgtgaatggc gtaatgaacg ctgtctttgt agaatctatc ggtattggtg
    60121 agtctatgta ctacggacca ggtgcgggtc aaaaaccaac tgcaacaagt gttgtagctg
    60181 atattgtccg tatcgttcgt cgtttgaatg atggtactat tggcaaagac ttcaacgaat
    60241 atagccgtga cttggtcttg gcaaatcctg aagatgtcaa agcaaactac tatttctcaa
    60301 tcttggctcc agactcaaaa ggtcaggtct tgaagttggc tgaaatcttc aatgctcaag
    60361 atatttcctt taagcaaatc cttcaagatg gcaaagaggg tgacaaggcg cgtgtcgtta
    60421 tcatcacaca caagattaat aaagcccagc ttgaaaatgt ctcagctgaa ttgaagaagg
    60481 tttcagaatt cgacctcttg aataccttca aggtgctagg agaataagat gaagattatt
    60541 gtacctgcaa ccagtgccaa tatcgggcca ggttttgact cggtcggtgt agctgtaacc
    60601 aagtatcttc aaattgaggt ctgcgaagaa cgagatgagt ggctgattga acaccagatt
    60661 ggcaaatgga ttccacatga tgagcgtaat ctcttgctca aaatcgcttt acaaattgta
    60721 ccagacttgc aaccaagacg cttgaaaatg accagtgatg tccctttggc gcgcggtttg
    60781 ggttcttcca gctcggttat cgttgctggg attgaactag ccaaccaact gggtcaactc
    60841 aacttatcag accatgaaaa attgcagtta gcgaccaaga ttgaagggca tcctgacaat
    60901 gtggctccag ccatttatgg taatctcgtt attgcaagtt ctgttgaagg gcaagtctct
    60961 gctatcgtag cagactttcc agagtgtgat tttctagctt acattccaaa ctatgaatta
    61021 cgtactcgcg acagccgtag tgtcttgcct aaaaaattgt cttataagga agctgttgct
    61081 gcaagttcta tcgccaatgt agcggttgct gccttgttgg caggagacat ggtgaccgct
    61141 gggcaagcaa tcgagggaga cctcttccat gagcgctatc gtcaggactt ggtaagagaa
    61201 tttgcgatga ttaagcaagt gaccaaagaa aatggggcct atgcaaccta cctttctggt
    61261 gctgggccga cagttatggt tctggcttct catgacaaga tgccaacaat taaggcagaa
    61321 ttggaaaagc aacctttcaa aggaaaactg catgacttga gagttgatac ccaaggtgtc
    61381 cgtgtagaag caaaataaag aatagaagat aggatgggga aactcttgac cagagggttt
    61441 catatccttt ttgtgaaaag aagtttatac tcaatgaaaa tcaaagagca aactaggaag
    61501 ctagccgcag gctgctcaaa acagtgtttt gaggttgcag atagaactga cgaagtcagt
    61561 aacatatata cggtaaggtg acgctgacgt ggtttgaaga gattttcgaa gagtattagt
    61621 taaaaacgtg ataaaggaga aataaagatg gcagaaattt atctagcagg tggttgtttt
    61681 tggggcctag aggaatattt ttcacgcatt tctggagtgc tagaaaccag tgttggctac
    61741 gctaatggtc aagtcgaaac gaccaattac cagttgatca aggaaacaga ccatgcagaa
    61801 acggtccaag tgatttacga tgagaaggaa gtgtcactca gagagatttt actttattat
    61861 ttccgagtta tcgatcctct atctatcaat caacaaggga atgaccgtgg tcgccaatat
    61921 cgaactggga tttattatca ggatgaagca gatttgccag ctatctacac agtggtacag
    61981 gagcaggaac gcatgctggg tcgaaagatt gcagtagaag tggagcaatt acgccactac
    62041 attctggctg aagactacca ccaagattat ctcaggaaga atccttcagg ttactgtcat
    62101 atcgatgtga ccgatgctga taagccattg attgatgcag caaactatga aaagcctagt
    62161 caagaggtgt tgaaggccag tctatctgaa gagtcttatc gtgtcacaca agaagctgct
    62221 acagaggctc catttaccaa tgcctatgac caaacctttg aagaggggat ttatgtagat
    62281 attacgacag gtgagccact cttttttgcc aaggataagt ttgcttcagg ttgtggttgg
    62341 ccaagtttta gccgtccgat ttccaaagag ttgattcatt attacaagga tctgagccat
    62401 ggaatggagc gaattgaagt tcgttctcgt tcaggcagtg ctcacttggg tcatgttttc
    62461 acagatggac cgcgggagtt aggcggcctc cgttactgta tcaattctgc ttctttacgc
    62521 tttgtggcca aggatgagat ggaaaaagca ggatatggct atctattgcc ttacttaaac
    62581 aaataaaaca gagagtgggg cttcccactt tcttcatttc tagaatatga atagaaggga
    62641 tttatgaaac acctattatc ttacttcaaa ccctacatca aggaatcaat tttagccccc
    62701 ttgttcaagc tgttagaagc tgtttttgag ctcttggttc ccatggtgat tgctgggatt
    62761 gttgaccaat ctttacctca gggagatcaa ggtcatctct ggatgcagat tggcctgctc
    62821 cttatctttg cagtaattgg cgttttagtg gccttgatag ctcaatttta ctcagcaaag
    62881 gcagcagtag gttttgctaa ggaattgaca aacgatcttt atcgtcatat tctttccttg
    62941 cccaaggaca gcagagaccg tctgacaaca tctagtttgg tcactcgctt gacttcggat
    63001 acctaccaga ttcagactgg tatcaatcaa ttcctgcgtc tctttttgcg agcgcccatt
    63061 atcgtttttg gtgccatttt tatggcttat cgaatctcaa ctgagttgac tttctggttc
    63121 ttagtcatgg ttgccatttt gaccattgtc attgtagggt tatctcgatt ggtcaatcct
    63181 ctctacagta gtctcagaaa gaaaacggac caactggttc aggaaacgcg ccagcaattg
    63241 caagggatgc gggttattcg tgcttttggt caagaaaaac gagagttaca gatttttcaa
    63301 acccttaacc aagtttatgc tagattacaa gaaaagacag gtttctggtc tagtttatta
    63361 acacctctga cctatctgat tgtcaatgga actcttctcg ttattatctg gcaaggctat
    63421 atttcaattc aaggaggagt gctcagtcaa ggtgctctca ttgctcttat caattacctc
    63481 ttacagattt tggtggaatt ggtcaagcta gccatgttga tcaattccct caaccagtcc
    63541 tatatctcag tcaagcgaat cgaggaagtc tttgttgagg ctccagagga tatccattca
    63601 gagttagaac aaaagcaagc taccagagat aaggttttac aagtccaaga attgactttt
    63661 acctatcctg atgcggccca gccttctctg agatacattt cctttgatat gactcaagga
    63721 caaattctag gtatcatcgg gggaactggt tctggtaaat caagcttggt gcaactctta
    63781 cttggacttt atccagtaga caaggggaac attgaccttt atcaaaatgg acgtagtcct
    63841 cttaatttgg agcagtggcg gtcttggatt gcctatgtac ctcaaaaggt cgaactcttt
    63901 aaaggaacca ttcgttccaa cttgactcta ggtttcaatc aagaagtatc tgaccaggaa
    63961 ctctggcagg ccttggagat tgcgcaagct aaggattttg tcagtgaaaa ggaaggactc
    64021 ttggatgctc tagttgaggc aggggggcga aatttctcag gtggacaaaa acaaagattg
    64081 tctatcgccc gagcagtctt gcgccaagct ccgtttctca tcctagatga tgcaacctcg
    64141 gcactggata ccattacaga gtccaagctc ttgaaagcta ttagagaaaa ttttccaaac
    64201 acgagcttaa ttttgatctc tcaacgaacc tcaactttac agatggcgga ccagattctc
    64261 ctcttggaaa aaggtgagtt gctagctgtt ggcaagcacg atgacttgat gaaatccagc
    64321 caagtctatt gtgaaatcaa tgcatcccaa catggaaagg aggactagaa tgaaacgaca
    64381 aactgtaaac cagacgctca aacgtttagc cgtagattta gcaagccatc ctttcctcct
    64441 tttcctagcc tttctaggaa ctattgctca agttggctta tcaatttacc tacctattct
    64501 gattgggcag gtcattgacc aagtcctagt ggctggttca tcaccagttt tttggcagat
    64561 ttttctccag atgctcttgg tggtaatagg aaatactctg gtacaatggg ccaatcctct
    64621 cctctataat cgtctaatct tctcttatac cagagattta cgggagcgaa tcatccataa
    64681 gctccatcgt ttaccgattg cctttgtaga taggcaaggt agtggagaga tggttagtcg
    64741 tgtaaccacg gacatcgaac agttggcagc tggcttgacc atgattttta accaattttt
    64801 cattggtgtt ttgatgattt tggtcagtat tctagccatg ctccaaattc atctcctcat
    64861 gactctctta gtcttgctgt tgacgccact gtccatggtg atttcacgct ttattgccaa
    64921 gaaatcctat catctcttcc agaagcaaac agagacgagg ggaattcaga ctcagttgat
    64981 tgaagaatcg cttagtcagc agactataat ccagtccttc aatgctcaaa cagaatttat
    65041 ccaaagattg cgtgaggctc atgacaacta ctcaggctat tctcagtcag ccatctttta
    65101 ttcttcaacg gtcaatcctt cgactcgctt tgtaaatgca ctcatttatg cccttttagc
    65161 tggagtagga gcttatcgta tcatgatggg ttcagccttg accgtcggtc gtttagtgac
    65221 ttttttgaac tatgttcagc aatacaccaa gccctttaac gatatttctt cagtgctagc
    65281 tgagttgcaa agtgctctgg cttgcgtaga gcgtatctat ggagtcttag atagccctga
    65341 agtggctgaa acaggtaagg aagtcttgac gaccagtgac caagttaagg gagctatttc
    65401 ctttaaacat gtctcttttg gctaccatcc tgaaaaaatt ttgattaagg acttgtctat
    65461 cgatattcca gctggtagta aggtagccat cgttggtccg acaggtgctg gaaaatcaac
    65521 tcttatcaat ctccttatgc gtttttatcc cattagctcg ggagatatct tgctggatgg
    65581 gcaatccatt tatgattata cacgagtatc attgagacag cagtttggta tggtgcttca
    65641 agaaacctgg ctcacacaag ggaccattca tgataatatt gcctttggca atcctgaagc
    65701 cagtcgagag caagtaattg ctgctgccaa agcagctaat gcagactttt tcatccaaca
    65761 gttgccacag ggatacgata ccaagttgga aaatgctgga gaatctctct ctgtcggcca
    65821 agctcagctc ttgaccatag cccgagtctt tctggctatt ccaaagattc ttatcttaga
    65881 cgaggcaact tcttccattg atacacggac agaagtgctg gtacaggatg cctttgcaaa
    65941 actcatgaag ggccgcacaa gtttcatcat tgctcaccgt ttgtcaacca ttcaggatgc
    66001 ggatttaatt cttgtcttag tagatggtga tattgttgaa tatggtaacc atcaagaact
    66061 catggataga aagggtaagt attaccaaat gcaaaaagct gcggctttta gttctgaata
    66121 agccattctc ttttgaaagt ttatggacga aaaaagttgc cttcgagtga cttttttgtt
    66181 acaatagcta gaaaaattgt tcactgtaat actcaatgaa aatcaaagag caaactagga
    66241 agctagccgt aggttgctca aagcacagct ttgaggttgt agataagact gacgaagtca
    66301 gttcaaaaca ctgttttgag gttgcagata gaactgacga agtcagctca aaacactgtt
    66361 ttgaggttgc agatagaact gacgaagtca gtaaccacac ctacggcaaa gtgaatctga
    66421 agtggtttga agagagtaca acttgtcttt tagaaaagga gcctataatg aaagtctttc
    66481 agcatgtaaa tatcgtgact tgtgatcaag atttccatgt ttatcttgat ggaatcttag
    66541 cagtcaagga ttctcaaatc gtctatgtcg gtcaagataa gccagcgttt ttagagcaag
    66601 ctgagcagat tatagactat cagggagctt ggattatgcc tggtttggtc aattgtcaca
    66661 cccattctgc aatgacaggt ctgagaggga tccgagatga cagcaatctc catgaatggc
    66721 tcaatgacta tatttggcca gcagaatctg agtttactcc cgacatgact accaatgcgg
    66781 tcaaagaagc cctgacagag atgctccagt caggaacaac aacctttaac gatatgtata
    66841 atcccaatgg tgtggatatc cagcaaattt atcaggtggt gaaaacttcc aagatgcgtt
    66901 gttatttttc tccgactctc ttttcttcag agacagaaac aactgctgag actataagta
    66961 gaactcgatc catcatagac gaaatcttaa aatataaaaa tccaaatttc aaggttatgg
    67021 tagcacctca ttctccgtat agctgcagta gagacttgct ggaagcgagt ttggaaatgg
    67081 caaaagagct aaatattccg ctccatgtcc atgtggcgga gaccaaggag gagtcaggaa
    67141 ttatcctcaa acgatacggc aaacgccccc ttgcttttct tgaagaactg ggttatttag
    67201 atcatccgtc cgtatttgct cacggggtcg aattaaacga gagagaaatt gaacgcttgg
    67261 catcttctca agtggctatc gcccacaatc ctatcagtaa cctcaaactg gcatcaggaa
    67321 ttgctccaat tatccagctc caaaaagcgg gagtagcagt cggaattgcg actgactcgg
    67381 ttgcttccaa taacaatcta gatatgtttg aggaaggaag gactgcagct cttcttcaga
    67441 agatgaaaag tggggatgcc agccagtttc caatcgaaac agctctcaag gtactgacaa
    67501 tcgaaggggc taaggtcctt ggaatggaaa atcagatagg aagtctggaa gtcggcaagc
    67561 aagcagattt tctggtcatt caaccacaag ggaaaattca tctccaacct caggaaaata
    67621 tgctgtctca cctggtttat gcagttaaat ctagtgatgt agatgatgtt tatatcgccg
    67681 gagaacaggt tgttaagcaa ggtcaagtcc tgacagtaga actttaaaag aaaaattacg
    67741 aaaaatttta aaaaaagttt gcaaaaatct tgcattcttt ttttgactat gctatactta
    67801 tatacggttt aaaaaaactg cctaagacag taggggagct cgactcataa atatcctacc
    67861 gaggacaaaa cgtatcatgt aaaaagaagc gtattgtact ttcgtgtcta ggtttgggcg
    67921 cgtttttctt tttgaaaaat tccccaagca aaataattac ggaggtgaac acactaatga
    67981 gtgaagcaat tattgctaaa aaagcggaac tagttgacgt agtagctgaa aaaatgaaag
    68041 ctgctgcatc tatcgtcgtt gtagacgctc gtggtttgac agttgagcaa gatacagttc
    68101 ttcgtcgtga gcttcgtgga agcgaagttg agtataaagt tattaaaaac tcaatcttgc
    68161 gtcgtgcagc tgaaaaagct ggtcttgaag atcttgcatc tgtatttgtt ggaccatctg
    68221 cagtagcatt ttctaatgaa gatgttatcg caccagcgaa aatcttgaac gacttttcta
    68281 aaaacgctga agcacttgaa attaaaggtg gtgcaatcga aggcgctgtc gcatctaaag
    68341 aagagattct tgcacttgca actcttccaa accgcgaagg acttctttct atgctccttt
    68401 ctgtacttca agcgccagtg cgcaacgttg ctcttgcagt caaagcggtt gcagaaagca
    68461 aagaagacgc ggcttaatct taagctacac agcgtagctt agctacgaaa aaaactatta
    68521 taaaatttaa aacttatttg gaggaaataa caatggcatt gaacattgaa aacattattg
    68581 ctgaaattaa agaagcttca atccttgaat tgaacgacct tgtaaaagct atcgaagaag
    68641 aatttggtgt aactgcagct gctcctgtag ctgttgctgc agctgatgca gctgatgctg
    68701 gtgctgctaa agattcattc gacgttgaat tgacatctgc aggcgacaaa aaagttggcg
    68761 ttatcaaagt tgtacgtgaa atcactggtc ttggtcttaa agaagctaaa gaacttgttg
    68821 acggtgcacc agcacttgtt aaagaaggcg ttgcaactgc agaagctgaa gaaatcaaag
    68881 ctaaattgga agaagctgga gcttcagtta ctcttaaata atagagtatc gcaatttgat
    68941 tgcggaatcc ctatttacca gtctttgaga gcgataagcg attgatagaa actgataaat
    69001 tgatttggtt tcctgccaaa aattc
//
LOCUS       DBEJKC010000003        57437 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.003, whole genome shotgun sequence.
ACCESSION   DBEJKC010000003 DBEJKC010000000
VERSION     DBEJKC010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 57437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57437
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.003"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(124..1104)
                     /locus_tag="ACL3G6_000191"
     CDS             complement(124..1104)
                     /locus_tag="ACL3G6_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HGR0544793.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTPPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(1420..3435)
                     /gene="recG"
                     /locus_tag="ACL3G6_000192"
     CDS             complement(1420..3435)
                     /gene="recG"
                     /locus_tag="ACL3G6_000192"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HGR0544794.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLDWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3454..4557)
                     /gene="alr"
                     /locus_tag="ACL3G6_000193"
     CDS             complement(3454..4557)
                     /gene="alr"
                     /locus_tag="ACL3G6_000193"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HGR0544795.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4547..4909)
                     /gene="acpS"
                     /locus_tag="ACL3G6_000194"
     CDS             complement(4547..4909)
                     /gene="acpS"
                     /locus_tag="ACL3G6_000194"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HGR0544796.1"
                     /translation="MIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGR
                     RQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLSIS
                     HTDQFVTASVILEENHES"
     gene            complement(4954..5985)
                     /locus_tag="ACL3G6_000195"
     CDS             complement(4954..5985)
                     /locus_tag="ACL3G6_000195"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGR0544797.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMELENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEVFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(5987..7018)
                     /locus_tag="ACL3G6_000196"
     CDS             complement(5987..7018)
                     /locus_tag="ACL3G6_000196"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGR0544798.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7099..9612)
                     /gene="secA"
                     /locus_tag="ACL3G6_000197"
     CDS             complement(7099..9612)
                     /gene="secA"
                     /locus_tag="ACL3G6_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HGR0544799.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(9758..10045)
                     /locus_tag="ACL3G6_000198"
     CDS             complement(9758..10045)
                     /locus_tag="ACL3G6_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544800.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLTFFFIPWDRAILGVRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            complement(10056..10706)
                     /locus_tag="ACL3G6_000199"
     CDS             complement(10056..10706)
                     /locus_tag="ACL3G6_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0544801.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGNNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISKDISDLCTDVLAVENGHIQYVKDIQS"
     gene            complement(10710..11351)
                     /locus_tag="ACL3G6_000200"
     CDS             complement(10710..11351)
                     /locus_tag="ACL3G6_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544802.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEVNLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLILSRLEEKFKKG"
     gene            complement(11344..12135)
                     /locus_tag="ACL3G6_000201"
     CDS             complement(11344..12135)
                     /locus_tag="ACL3G6_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544803.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAILTHFFGTFSPLGWNSLFSDGSSLQR
                     LLDGEITSYLFFTCVLLIGIFINAVYFLQIVDYLGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            complement(12320..12655)
                     /locus_tag="ACL3G6_000202"
     CDS             complement(12320..12655)
                     /locus_tag="ACL3G6_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544804.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNVADIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            complement(12795..13130)
                     /locus_tag="ACL3G6_000203"
     CDS             complement(12795..13130)
                     /locus_tag="ACL3G6_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544805.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(13221..14531)
                     /gene="der"
                     /locus_tag="ACL3G6_000204"
     CDS             complement(13221..14531)
                     /gene="der"
                     /locus_tag="ACL3G6_000204"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HGR0544806.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(14545..15258)
                     /locus_tag="ACL3G6_000205"
     CDS             complement(14545..15258)
                     /locus_tag="ACL3G6_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HGR0544807.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(15255..16151)
                     /gene="dnaI"
                     /locus_tag="ACL3G6_000206"
     CDS             complement(15255..16151)
                     /gene="dnaI"
                     /locus_tag="ACL3G6_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HGR0544808.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFVQQESLNQDEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKKRLNLINFPSSLKNVSFLDVYRDDVQRLTVLKRMIEFVNDYPNNLKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16152..17321)
                     /locus_tag="ACL3G6_000207"
     CDS             complement(16152..17321)
                     /locus_tag="ACL3G6_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGR0544809.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLVLHAPLSSQD
                     FLEHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     EQKAKTQKQNQTAPAKTNIPKWSNPEYKNTSSAEELEEMERQTLELLAKLDNGGD"
     gene            complement(17322..17795)
                     /gene="nrdR"
                     /locus_tag="ACL3G6_000208"
     CDS             complement(17322..17795)
                     /gene="nrdR"
                     /locus_tag="ACL3G6_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HGR0544810.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            17935..18300
                     /locus_tag="ACL3G6_000209"
     CDS             17935..18300
                     /locus_tag="ACL3G6_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0544811.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            18305..19000
                     /locus_tag="ACL3G6_000210"
     CDS             18305..19000
                     /locus_tag="ACL3G6_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0544812.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19017..19784
                     /locus_tag="ACL3G6_000211"
     CDS             19017..19784
                     /locus_tag="ACL3G6_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544813.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20137..21336)
                     /locus_tag="ACL3G6_000212"
     CDS             complement(20137..21336)
                     /locus_tag="ACL3G6_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0544814.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHIQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(21333..22226)
                     /locus_tag="ACL3G6_000213"
     CDS             complement(21333..22226)
                     /locus_tag="ACL3G6_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0544815.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            22348..22539
                     /locus_tag="ACL3G6_000214"
     CDS             22348..22539
                     /locus_tag="ACL3G6_000214"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544816.1"
                     /translation="MKSKERTRKLAVGCSKYSFEVADKTDEVSSKHCFEVVDRTDEVS
                     NYIYGKAKLTWFEEIFEEY"
     gene            22907..23120
                     /locus_tag="ACL3G6_000215"
                     /pseudo
     CDS             22907..23120
                     /locus_tag="ACL3G6_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            23535..24152
                     /locus_tag="ACL3G6_000216"
     CDS             23535..24152
                     /locus_tag="ACL3G6_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HGR0544817.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(24472..25359)
                     /gene="scrK"
                     /locus_tag="ACL3G6_000217"
     CDS             complement(24472..25359)
                     /gene="scrK"
                     /locus_tag="ACL3G6_000217"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HGR0544818.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGENIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(25508..27391)
                     /locus_tag="ACL3G6_000218"
     CDS             complement(25508..27391)
                     /locus_tag="ACL3G6_000218"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HGR0544819.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            27768..29222
                     /locus_tag="ACL3G6_000219"
     CDS             27768..29222
                     /locus_tag="ACL3G6_000219"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HGR0544820.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            29203..30168
                     /locus_tag="ACL3G6_000220"
     CDS             29203..30168
                     /locus_tag="ACL3G6_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0544821.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(30203..31477)
                     /locus_tag="ACL3G6_000221"
     CDS             complement(30203..31477)
                     /locus_tag="ACL3G6_000221"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HGR0544822.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(31477..32649)
                     /locus_tag="ACL3G6_000222"
     CDS             complement(31477..32649)
                     /locus_tag="ACL3G6_000222"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HGR0544823.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(32780..33028)
                     /locus_tag="ACL3G6_000223"
     CDS             complement(32780..33028)
                     /locus_tag="ACL3G6_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544824.1"
                     /translation="MVSSWGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(33096..33719)
                     /locus_tag="ACL3G6_000224"
                     /pseudo
     CDS             complement(33096..33719)
                     /locus_tag="ACL3G6_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(33781..34230)
                     /locus_tag="ACL3G6_000225"
     CDS             complement(33781..34230)
                     /locus_tag="ACL3G6_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGR0544825.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(34232..34990)
                     /locus_tag="ACL3G6_000226"
     CDS             complement(34232..34990)
                     /locus_tag="ACL3G6_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGR0544826.1"
                     /translation="MEESKELNTVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(35121..37100)
                     /gene="stkP"
                     /locus_tag="ACL3G6_000227"
     CDS             complement(35121..37100)
                     /gene="stkP"
                     /locus_tag="ACL3G6_000227"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase StkP"
                     /protein_id="HGR0544827.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKTPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPIQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(37097..37837)
                     /locus_tag="ACL3G6_000228"
     CDS             complement(37097..37837)
                     /locus_tag="ACL3G6_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HGR0544828.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(37852..39165)
                     /gene="rsmB"
                     /locus_tag="ACL3G6_000229"
     CDS             complement(37852..39165)
                     /gene="rsmB"
                     /locus_tag="ACL3G6_000229"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HGR0544829.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(39158..40093)
                     /gene="fmt"
                     /locus_tag="ACL3G6_000230"
     CDS             complement(39158..40093)
                     /gene="fmt"
                     /locus_tag="ACL3G6_000230"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HGR0544830.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGCDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPKEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(40106..42502)
                     /locus_tag="ACL3G6_000231"
     CDS             complement(40106..42502)
                     /locus_tag="ACL3G6_000231"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HGR0544831.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYRHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(42568..42882)
                     /gene="rpoZ"
                     /locus_tag="ACL3G6_000232"
     CDS             complement(42568..42882)
                     /gene="rpoZ"
                     /locus_tag="ACL3G6_000232"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGR0544832.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(42907..43533)
                     /gene="gmk"
                     /locus_tag="ACL3G6_000233"
     CDS             complement(42907..43533)
                     /gene="gmk"
                     /locus_tag="ACL3G6_000233"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HGR0544833.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(43663..45276)
                     /locus_tag="ACL3G6_000234"
     CDS             complement(43663..45276)
                     /locus_tag="ACL3G6_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HGR0544834.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(45545..45775)
                     /locus_tag="ACL3G6_000235"
     CDS             complement(45545..45775)
                     /locus_tag="ACL3G6_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HGR0544835.1"
                     /translation="MEGVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMDKIRAGH"
     gene            complement(46013..47110)
                     /locus_tag="ACL3G6_000236"
     CDS             complement(46013..47110)
                     /locus_tag="ACL3G6_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGR0544836.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQSMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            complement(47120..47860)
                     /locus_tag="ACL3G6_000237"
     CDS             complement(47120..47860)
                     /locus_tag="ACL3G6_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0544837.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKEKKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(47969..48322)
                     /gene="rsfS"
                     /locus_tag="ACL3G6_000238"
     CDS             complement(47969..48322)
                     /gene="rsfS"
                     /locus_tag="ACL3G6_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HGR0544838.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(48335..48835)
                     /locus_tag="ACL3G6_000239"
     CDS             complement(48335..48835)
                     /locus_tag="ACL3G6_000239"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGR0544839.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(48836..49429)
                     /gene="yqeK"
                     /locus_tag="ACL3G6_000240"
     CDS             complement(48836..49429)
                     /gene="yqeK"
                     /locus_tag="ACL3G6_000240"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HGR0544840.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            complement(49429..50058)
                     /locus_tag="ACL3G6_000241"
     CDS             complement(49429..50058)
                     /locus_tag="ACL3G6_000241"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HGR0544841.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVAYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(50110..50421)
                     /gene="yhbY"
                     /locus_tag="ACL3G6_000242"
     CDS             complement(50110..50421)
                     /gene="yhbY"
                     /locus_tag="ACL3G6_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HGR0544842.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(50635..51741)
                     /gene="yqeH"
                     /locus_tag="ACL3G6_000243"
     CDS             complement(50635..51741)
                     /gene="yqeH"
                     /locus_tag="ACL3G6_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HGR0544843.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPSLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            complement(51744..52271)
                     /locus_tag="ACL3G6_000244"
     CDS             complement(51744..52271)
                     /locus_tag="ACL3G6_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HGR0544844.1"
                     /translation="MAIENYIPDFAVEAVYDLTVPSLQAQGIKAVLVDLDNTLIAWNN
                     PDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVEKFGIDYVYWALKPFTFGIDRA
                     MKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKPLVQHDSIKTQINRTRERRVMR
                     KITEKYGPITYKKGI"
     gene            complement(52286..53194)
                     /locus_tag="ACL3G6_000245"
     CDS             complement(52286..53194)
                     /locus_tag="ACL3G6_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGR0544845.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(53251..53811)
                     /locus_tag="ACL3G6_000246"
     CDS             complement(53251..53811)
                     /locus_tag="ACL3G6_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HGR0544846.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQVLHFVPNRNITVVSNFSRTD"
     gene            53950..55161
                     /gene="sstT"
                     /locus_tag="ACL3G6_000247"
                     /pseudo
     CDS             53950..55161
                     /gene="sstT"
                     /locus_tag="ACL3G6_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            55229..56182
                     /locus_tag="ACL3G6_000248"
     CDS             55229..56182
                     /locus_tag="ACL3G6_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGR0544847.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            56325..56705
                     /locus_tag="ACL3G6_000249"
     CDS             56325..56705
                     /locus_tag="ACL3G6_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGR0544848.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            56804..57025
                     /locus_tag="ACL3G6_000250"
     CDS             56804..57025
                     /locus_tag="ACL3G6_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGR0544849.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            57042..57356
                     /gene="trxA"
                     /locus_tag="ACL3G6_000251"
     CDS             57042..57356
                     /gene="trxA"
                     /locus_tag="ACL3G6_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGR0544850.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
BASE COUNT        16289 a        13083 c        11079 g        16986 t
ORIGIN      
        1 ttgtcctatt cttgtttcat tttactatat ttccatgata aaacgcatag tatcaagttt
       61 ttttaatccc ctgatactat gcgtgtttgt aatttttaag attttgtgct tagagtcgac
      121 tccttatttt agatatttaa aaggaatctc acttccacag agccagttgt agacttggtc
      181 attgacaaat acattcatgg cttcgtgagc atactcaggc atgatacgat aggttttatc
      241 gcaggtcaga cgattataaa tcgcaaactg ggtaatggga tagcaaacat cgtcgtccaa
      301 gcccgtaatc atcttaacct caccttggat acgatgggca agatttttga catcgatata
      361 ggcaagggtc gccatgattt cctcctctgt ttcatggaag gggtcgtgaa acttgaaata
      421 acggaaaagt tcgtcgtaag cctcgctagt attaccaatc tcaatcaccc gtctgaagtc
      481 tgacaagaag ggataaatgg caactgtttt ctgaattcga ggattgagcg ctgctgcaac
      541 tagagctaga gcccctcctt gtgaggcacc atagctagaa agacgcttct catcaacctg
      601 agacagacta gcaacaattt cgaccaactg gtaaatatcc agataaacat ccttataaaa
      661 gaggtggtcc cgaccttcca tagcaccacg gataatatgc cccttcacgg tatttcctaa
      721 aggagaacgc aagccgtctt gtgagtaacc tgactggccc cgcacatcca tggaaacaac
      781 accataacca gctacggtga agcccagcat gtcggcccag tcccagccac gtcccatata
      841 accatgaaaa tggaagatta gtggaacctt ctcctcactc tttggaagaa caatgcgtgc
      901 atagaccttt ccttccttgc ttccttcaaa tgttaactca tagcacttga cttgaggaat
      961 gtggaaatct ctttcctcca agtggtagga tggaggtgtg gaaacatttt tcacttcccc
     1021 atcccagaaa gcatcaaagt cttccggaac ctcatccctt cctctatagg tcttaatttc
     1081 ttctagcaaa gctggatttt tcatagcatg ctccttttat tttgtaatcg ttaccacaac
     1141 tgtagcatat ctatgtaatc aatgcaagaa agaaggataa atagaaagtg aatttagatt
     1201 ctttactttt aggatgatgg gctgaaagta gttttagaaa cgaaaaagag catttcgctc
     1261 tctcttctgt ttatactagt tttttgcttc cttcttttgg aaagtggttt ggtaatttac
     1321 tttaatcgtt actgtcatat gagagtcctc gtttcttttt gatgacttta gtataagagc
     1381 caaacctaaa aactagctta agttttcctt agagaaagct taatccagat gttctttctt
     1441 ttccagatga agggcaatca tgcgccactc tggatcttct tgccaagctt ctatagaact
     1501 aatgtagcta gcaacctttc ttgcttcttc taaaatcgga aaatcttcga taatatcagc
     1561 cacttggaac tctggaagtc ctgactgtct ggttccaaaa atctcaccag aaccacgcat
     1621 tttcaaatct tcctccgcaa ggacaaatcc attggtcgtt tctgtcatga tgcgcatgcg
     1681 gtctttccca gaatccgtct tgggattggc aacgagaaca gcgtaggact gcttgtcccc
     1741 ccgaccgaca cgacctctaa gctggtgaag ttgactgaga ccgaagcgat cggcatccat
     1801 gataatcatg acagtcgcat tgggaacgtt gaccccaacc tcaataaccg tcgtcgaaac
     1861 cagaatatcc gtctttctct ccttgaaatc ctgcatgatc tggtcttttt cgtcactctt
     1921 catcctacca tgtagaagag ccacctctgc cttgcctgca aaatgagtcg tcaactcctc
     1981 tgataaggca atggcatttt tcaaatctag agcttctgat tcttcaatca aaggagagat
     2041 gacataggct tgggaacctt tttgaatttc cccctctaac caagtcaaga cctgaggtag
     2101 ttgctcatgt ttgatccagc gcgtcacaat aggcttccga cctgctggca tctggtcgat
     2161 aatggaaaca tccatatctc caaaggctgt gatggcaagc gtccgtggaa tgggagtcgc
     2221 cgtcatcatg aggacatctg gattgtcacc tttttcccgt aaaatacgcc tttgccctac
     2281 accaaaacgg tgctgctcat cgataataat caaaccaaga cgagcatact ccaccccatc
     2341 ttgtatcaga gcgtgagttc ctataatcaa atcagcctca cccttggcaa tggtctccaa
     2401 gacttctctc ttttctgcag ctttcaagga acctgtcaag agagccagtt tcaaattggg
     2461 aaaaaggttc tgtaaactct caaagtgttg ctctgcgagg atttctgttg gtaccattag
     2521 ggcagcctga taacctgctg tcactgccgc aaacatggcc aagccagcga ctaccgtttt
     2581 tccactcccc acatctcctt gtaggagacg attcatgtgg tggtcggact tcatatcagt
     2641 taaaatttcc tgcaaactct tttcctgagc ttgggtcagg gcaaaaggaa gacttgcttt
     2701 aactgctgtc actttttcct gagaccaatc cagaaccaga ccacttccct gaactctatt
     2761 ttcagacttg agcgtctgca gctgcatttg gaaataaaag agttcctcaa acttgatacg
     2821 gcgaagagcc tgcttgtatt ctgccaaatc ctttggaaaa tgcatagctc ggactgcctg
     2881 acaacgggac atgagtttgt atttgtctag taaagactgg ggcagatttt cttctatcaa
     2941 gaggtccagt ccctgatcaa aagccgtctt gatgaccttg accagactgg cctgactgat
     3001 tccctgagcc agacgataga caggctggag gtcatcttct acctgagcca gaaccttcat
     3061 cccagtcaga ctagccttag cgcggtccca ttttccaaag acagcaaggg ttgctcccaa
     3121 ctctatttta tcagccagat agggctggtt aaagaaattc accgcaaaaa cgacctctcc
     3181 ctgcttgaga ctaaaacgca ggcgattgcg cttgaaacca taatactgga cactagcagg
     3241 agtcactacc tgaccagaaa gaactgcctt ctcaccgtct tccagctcca gcacctgctt
     3301 ggttttgaag tcttcataac ggaaaggaaa gtagagcaag agatcttgca agttttcaat
     3361 tcctagtttg gcgtattttt ctgctgactt tggtcccaca ccaggcaaga catgcaaggg
     3421 ttgatgtaga ttcatgctcc actcctttct tttctaataa tattctctcg gaatacggtc
     3481 gctgaggagg caaaccacct catagttaat ggttacgcgg taggtcgcta cctgagttgc
     3541 agtgatttcc ttatccccat tggagccaat caaggttacc ttggttccta gcggataaag
     3601 cttaggcaat cgaatagtga tttggtccat cgaaaccctg ccgacaattg ggcaagcttg
     3661 gccatctacc aagacagaga aattttgcat gtctcttgtc catccatctg catacccgat
     3721 tggcacggtc gcgatgactt gctcgctatc cgcttgataa gttgctccat agcccatgca
     3781 agctccagct ggaactgtct tgacatgaac cagagcagac tccaaggtca aggccggtat
     3841 caaatcataa ggcaaatcca agaccgctcc acttggattg aggccataca tggcatctcc
     3901 catacgaacc gcattgaaaa tagtctctac atgccaaaga gtcgttgcag aattgctagc
     3961 atgaaccagc tctggaactt ccttcatact agctaaaata gttttaaacc gttctaactg
     4021 ggcattaaaa tagtcatctg attcctcatc agcagtagca aagtgggtaa agattccttc
     4081 aacacgaaca ccgtgttgtt gtagcaaatc ttgagcctgc tcaacctcac tggcctctct
     4141 aaaaccaatc cgtcccatcc ctgaatcaat cttgaggtgg actgtcaatc cagttaggtc
     4201 cacttcctta tctaagagtg cttgaatcca ctccagtcca gccactgtca aggtgaagtc
     4261 atattcttta gctagagcaa cagcttcgat ttcagaaact cctaaaatga ggattggctt
     4321 gctgagtcca gcttgtctga gttcaatggc ttcatcgata ttggaaacgc aaaagccatc
     4381 aacatcatct tgaattgcct tggcaacggc aacagctcca tgaccataag cattggcctt
     4441 gaccacagcc aacttgagcg ttccttgagg gatatgagcc cccatttgct gaatattttg
     4501 tcgaatagct cccagatgaa tcagagcctt ggttggtcta tgtggactag ctttcatgat
     4561 tttcctccaa aatgacactg gctgtcacaa actgatcggt gtggctgata gacagccaaa
     4621 tctttcctga aaatggtgcc tgactaaaat aaggcgcccc acgttcattg ttcaagactt
     4681 ccaaatcctg aaaaccgagc ttgctaatgc ccgttcccat agccttggaa aaggcctcct
     4741 tagccgacca gcgaccagct aaatattcta tttgcctgcg tcctttgaga ctggtgaagc
     4801 gctccatttc ctgagcggtc agtacacgct tagcaaatcc ttcatgtcgt gtaactgcgc
     4861 tttctatcga agccaattct tcgatgtcaa ttccgtgtcc aactatcatt ctcatcaaaa
     4921 ggagttgaga ttccccaact ccatcctttt cacttatttt gtcaaggtaa cataaatctc
     4981 ttctaccaag gcctctgtat tttcccaacc taggcaaggg tcagtaatag agcaaccaaa
     5041 gacctctggt tggttttgac gaccatctgc taggtaagat tcaatcataa atcctcgaac
     5101 cgtcttttta attttctcat tccaatcacg attctgcaag gtctggcgaa caattcgaat
     5161 ctgctccata tattgcttgc ctgagttatc atggttggtg tcaatgagga taaaaggatt
     5221 ttcaagttcc atggtttcat agcgttcaat ggcttggagt aggttttcat agtagtaatt
     5281 cggcatataa ttgccatact cgttgactgc tccacggagg ataacatggg ccaaaggatt
     5341 acctgatgtc tcaacttcct gcccatgata aaggaaggtt tgcttgtttt gagcagcata
     5401 gatggcgtta aacataacac ccaaatttcc tgaggttgga tttttcatcc ctactggtgc
     5461 atcaatccca gaagccacaa agcggtgctc ttggtcttcc acagaacgag ctccaacggc
     5521 atggtagctg accaagtcat ccaccaagat cagatttgac ggataaagca tctcatctgc
     5581 cgttgtcaaa ccagtctctg taatcacgcg gtagtgcaac tggcgcacag cctgcaagcc
     5641 gttaatcagg cttggagcct tagaagtatc tggctggtga accaatcctt tatagccgtc
     5701 tccattggta cgaggcttag cagtatacac gcgcatgacc atgaaaatct tgtccgctac
     5761 cttcttttgc aaggcggata aacggcgagc atattccaag accgcctctt cattatcaga
     5821 agagcaagga ccaatcacca agagaatacg gtcatcttcc cctgaaataa tatctgccaa
     5881 ttccctgtca cggctttcct tgagtctcaa ggcttccgca gacaattggg tttcagcctt
     5941 gatgacttcc atatcgattt cttgaccttt ttcaataaat gccatcttat tctcctaacg
     6001 ttttgtaaat ttctctgaca agagcttctg tgttatccca acccaggcaa gggtctgtga
     6061 tagacttacc aaatacttct ggctcatttt gtcgaccatc ttccagataa gactcaatca
     6121 taaaaccacg aacgaactgc ttaatttttt cattccaagc acggttaatc aaggtctggc
     6181 ggacaattcg gatctgttca atatactgct taccagaatt gtcatgattg gtatcaatga
     6241 tgataaaagg attttccaag cccattttct catactgggc aatggtatca attaaattgt
     6301 cataatagta gttgggaata ttttttccat actcattaag agcaccacga agaatagcgt
     6361 gtgaaagcgg gttcccagtt gtttctactt cttttcctaa gaaaaggaaa ctttgtttgt
     6421 tttgagcagc ataaatccca ttaaacatga cattgagatt tccagaggtt ggatttttaa
     6481 aaccagtaga aaatcctgcc ccacttgcca caaagcggtg ttgctggtct tcaactgaac
     6541 gggcaccaac tgccatgtaa gaaatcaaat catctacaag cggaaggttt tcaggataaa
     6601 gcatttcatc agcagttgtc atccctgttt ctgtgatgac acgatagtga agatggcgaa
     6661 cggctttgat tccattgata agactaggcg cttctgtcgc gttaggctgg tgaatcaagc
     6721 ccttatagcc atctccgttg gtacggggtt tggcagtata aacacgcata accataaaga
     6781 tacgatctgc cacttcttct tgtaggactg ccaaacgctt agcgtattca aggacagctt
     6841 cttcgttgtc agatgagcat ggcccgatta ccaagagaat tcgctggtct tctccacgta
     6901 taatggcttc tagctcttga tctcgctgtg atttcctctc caaagcctga ccttctaatt
     6961 ttgacaaggc acgaacttct tctatattta ttttagagct ttttgctgta aataccataa
     7021 ctcatctcct tataaagcaa acggataccc agtaaaaatt tacttttcac aagatatccg
     7081 cctctaaact atctcatttt attgtctttt accgtgacag tttttaaatt tcttaccaga
     7141 accacatggg caaagttcat tgcgtccaat ctggctcaaa tccaaatctt ctggcatact
     7201 tgcttggtga gcagcgatat tgcgagtcgc tgttgtactg atatgacgtt ctgcctgtgg
     7261 tctttcttgt tcatgaattt gtgctttcat catcaagcgt gtcacatcaa actcaatcga
     7321 accaatcata tcattaaaca tacggaaacc ttctgcctga tactcaacaa cagggttgtt
     7381 ctgagcatag ccacgaagtc caaccgcgtt acgcaattga tcaagggcat cgatatgatc
     7441 tgtccacttg ttatccacca ctcgtagaat caaaactttt tggaattctt taactgcttc
     7501 ttcatcgcgt agttttgaaa cctgactatc gtaaaccttc aaggcacgtt ggaaaagctc
     7561 ttccttgatg gccttatcag acaagcctga caagtcttcc atcgtaatag aatcttcagg
     7621 aagcaagttg tacttagcaa agttcaaaat tgcctctagt ttttcatctt gtttggcacg
     7681 cgcatgacca tcaacgacac gttcaatcgt gcgtttgatc atagactgaa tttcaggtgc
     7741 caagtcacga tctgcagtga tgacatcgta acgttgagca tagataatct cacgttgttc
     7801 acgcatgaca tcatcgtatt gaaggacttg tttacgggta tcgtagttat ttccttcgac
     7861 acgtttctga gctgcttcaa cctgacgcgt caacatgcga gactcaatcg cctcttcaga
     7921 catgttcaag cgttcaaaga ttcccttcaa gcgttcagaa ccaaaacgtt tcatcaaatc
     7981 atcttcaaga gataggtaga attgtgactc acctggatct ccttgacgac ctgaacgtcc
     8041 acgaagctgg ttatcgatac gacgactttc atgacgttct gtaccaataa cacaaagtcc
     8101 tccaagttca cgaacacctt caccaagctt gatgtcggta ccacgacccg ccatgttggt
     8161 tgcgatggta acggcaccac gttgaccagc attcatgatg atttgggctt ctctatagtg
     8221 gtttttggca ttcaagactt cgtgaggaac accagctgca accaatttct tagaaatgta
     8281 gtcactagtt tcaaccgcta ctgtaccaac caagacaggt tgaccctttt ggtaacgagc
     8341 cttaacgtct tcgacaaccg ctttaaactt agattctata cttgcataaa gaaggtctga
     8401 gtggtcaata cgttgaacag gacggtttgt tgggattgga ataacacgaa tgttgtagat
     8461 ttcacggaat tcttcttcct cagtcttacc tgtacccgtc ataccagaca atttcttgta
     8521 catacggaaa aggttttggt acgtgattga ggcagatgtc ttggtttcat cctggattgg
     8581 cacaccttct ttggcttcaa tagcttggtg caatccatca gaataacgac gaccttccat
     8641 ggtacgacct gtaaattggt cgacaatcaa gatttcttgc tcttcgctca ccacatagtc
     8701 aatatcgaga agcatgatgt agttggcacg aagggcgtta tcgataaagt gggtcaaagc
     8761 cacgttttcg atgtcataga ggttttcaag tttgaagtag ctttcagccc tgtcaatccc
     8821 tgaatcagac aaaccaatag tcttagactg cacatcgatg atgtagtcat ctttgttcaa
     8881 agattttaca tagtggtctg ccatgtgata caactgactg gtttcaaccg cattggcacc
     8941 tgatacaatc aaaggtgtac gagcctcgtc aatcaagata gagtcaacct catcgaccaa
     9001 ggcatagtta agcggacgtt gtaccatgtt ttcagcgcga acgaccatat tgtcacgaag
     9061 gtagtcaaat ccgatttctg agttagttga gtaagtaata tcacactcat aggcttcttt
     9121 tttctccatt ggagatttgg tagccaagtt aatccctact gacaaaccaa gccaagagta
     9181 caattcaccc atctcagtcg cgtcacgttc tgacaggtat tcattaaccg taactacgtg
     9241 aaccccttta cctgaaaggg cattgaggta taccggcatg gtcgcagtca aggttttccc
     9301 ttcccctgta cgcatctctg gcacgtcacc atggtgaaga acaatccccc ccatgacctg
     9361 aaccttataa gggaagagac ctaggacacg tttggcacct tcacggacaa ccgcaaatgc
     9421 ttcgtaaagc aatgaatcca gtgattctcc attttgataa cgttccttaa attcaactgt
     9481 ttttgctttt agttggtcgt cagtcaaagc agccatttgg tcttcgtatt tgaaaacctt
     9541 gtcagccatc ttttccagac gacggatttc tcctttatca ttttcgataa ttgtttttaa
     9601 aatattagcc atgtttttcc ttactttaaa ttccgaatat tttagaatgt tcctttaatt
     9661 ttagcacaat tactgattat tttcaaggaa gaatccccat tttgaaaagg aaaaagaggt
     9721 tagttttcaa gctaacctct ccgactttta tgatgcttta attgccaaaa atcggcaaaa
     9781 tggcaaatgt gataaataag ttaatccaaa gagaaagaca gcaaatcagt ccaaaaacaa
     9841 agagactgac tttcttggac agcaaggcca tcaaaatgga cagaattcca aaagctagca
     9901 agattttctg tatgatgaag atgtcaatcc ttacccccag aatcgctcta tcccaaggga
     9961 taaagaagaa agtcagccag atcagcagaa ctaaaccaat ataaaccttg gaatagcgtg
    10021 taataaatga ttttagatgt gccataagcc atctcctagg attgtatatc ctttacatat
    10081 tgtatatgtc cattttcgac agctaataca tctgtacaaa ggtctgaaat atctttcgat
    10141 atgtgcgacg tcaggataac cagaccattt tcttttttca ggtaagataa aatgacctgt
    10201 ttggttaacc tcacactctt ctcatccaaa gcattcatag gttcatcgag aaagagtata
    10261 gaaggagagg aaataaaggc ttgaatcaag gccatttttt gctttgttcc caaggataaa
    10321 tgacggtatt caacgtcttc aaattcctgt aaatcatagt attgaatcca ataggcaatt
    10381 cttttttccg taactttaga tgaaaaatac cttaacagtt ccaaattttc tctcagggat
    10441 aaatgagata aaaactcgac tttttcaatt aaaattcctg catcctgaat ataatgattt
    10501 tttaccccgt aaactttacc atcttgaaga acttttcctt tgtcaagctt aatataacca
    10561 gcaagtatct ttaaaagaac cgtcttgcca gatccattat tacctttaag tccataaatt
    10621 tttcctgatt gaaacaccaa attcaactga tttaaaatag gtcttttccc ataaattttc
    10681 tgtccattta taatttcaag tctcatcgtt tatcctttct taaatttctc ttccaagcga
    10741 ctaagaatca acataactaa taagcttaag agtactaaat acactgttac aatatgatcc
    10801 atcatccatt cttgtcccac aaatgccaaa aaatagagaa aaaaagaaaa accagcgccc
    10861 gcactaatca gtgctatcag ataagacagt agtaagtaca acatcattaa ctgagcaagt
    10921 aaaaagaaaa gtgcgactgt tttgaaatga attcctagag gaagtaaacc aagaaaccag
    10981 acaaacaaat cttgagtaaa aaatttagaa atgacaacca atcgtttcct tgtataatcg
    11041 aaaaaggagc ttgattgata gcgaatcaag tgatggtaat ggtctgccaa atcactttca
    11101 agtaaaatga cagagagcca tcctaccatg aaaagcgaaa ggtttaacaa gagtttgggg
    11161 atttctaaat tcacttcaga atagtcatta taggaaaaaa ttgaaatcaa ttctctcttg
    11221 aaaaagataa cagcatcctg cttttgaacc gctgttgaca atagatggtt tatcaaaatc
    11281 atcatcagaa ctatacgaag tagtaaaaca atctttctct ttagcaaaat attgttaaaa
    11341 ttcttaaaca ttatcttcat atttttcaag caccatgtaa gggacaatat aaaggatata
    11401 aggagtaaag agtttcatca aacttacatc cccatagcta gcttgcatca aactcgtcat
    11461 aggaaccata tagtaaggca aggcactata gagcagcata gaaccaagcc aaagaaacat
    11521 caaataggtg attgccgaac gagtcacatt tcctaaataa tcaactattt gtaaaaaata
    11581 gactgcattg atgaaaatac cgattagtag gacacaagta aagaacaaat agcttgttat
    11641 ctctccatct aggagccttt gtaaactact cccatcagaa aatagagaat tccatccaag
    11701 aggagaaaaa gtcccaaaga aatgagttaa aattgcaatt atcagcacag tcactaaata
    11761 tatcaaacaa gggatacttg caacttgcaa agtcaacttt ctttttaacc cttgataact
    11821 cacttctctt ccaatactca atcgtaaaac tttatttttc agctcaatat attgaaaacc
    11881 tagcaaaaca atgatgattg gaataataaa tgattgataa aaacctagat tgaactggag
    11941 aatacgaaaa tctaatgctg attttaataa gtcattttta attgcttgtc catcgaattt
    12001 agctagatcg ggcgcatgaa tatcaaaaaa gaaataagtc atcaaaacat cacgataaac
    12061 caaagcaaga aaaagcaaag taagcaagac ataaacaaat ttatgccttg ccaaagttaa
    12121 gagaggaatc ttcataagcc acctcctaca aatagaaagt aatataatac tcaatgaaaa
    12181 tcaaagagca aactaggaaa ctagccgcaa gttgctcaaa gcactgcttt gaggttgtag
    12241 ataagactga cgaagtcagt tacatatata atccaaggcg acgttgacgt ggtttgaaga
    12301 gattttcgaa gagtataaat caatgccttc cgcctttaga cttccctagt tcccgtctca
    12361 agtcaagcat ttttttgaaa cagatatagt ctaaccagtc actagcaaaa gcgataagta
    12421 gtaataatag ccaaataccc cataacttga tgtctgccac atttctcaag acgatattga
    12481 aaaacagaac tgaaaaaact gtccaagcaa ggctaaaaag agcatagagg gtgatgtaaa
    12541 tccagtaaaa atagtaaaaa attgggaaaa atttactttc tctattatcc ttgtcaatcc
    12601 agctgaaaaa gtaaaaacag ggtaataaga ttatcatttt aaacaagtgt tccatcacaa
    12661 gcctcctttt ttaaattgtt ttctttagtt tcgttctatt aaatgttatt accaatataa
    12721 accttggaat agcgtgtaat aaatgatttt agaggtacca taagccacct cctacaaata
    12781 gaaaccgata taaatcaatg ccttccaccc ttagacttcc ctagttcctg tctcaagcga
    12841 aacatttctt tgaaacagga ataagttaac caattcatac caatagctag cagaataaaa
    12901 agaaaccaaa tgccccataa cttgatatct gtcacatttc tcaagacggt attgaaaaac
    12961 agaactgaaa caactgtcca agcaaggcta aaaagagaat agaaggggat gtaaaaccag
    13021 taaaaataat aaaaaattgg aaaaaactta ctatttctgt tggccttctc aatccagtta
    13081 tcaaaataaa agtacggtgc taaaagtaag aatttaaaca aatgttccat caccgacatc
    13141 accctccttc ttttgatagc gttttctatt attttattat atcaaaaaaa tccggaactg
    13201 tcattccaga ttctactttt ttatttgcgt tttcttgcga tgagatgaat cggtgttccc
    13261 tcaaaaacaa aggccttgcg gatttgattt tccaagaaac gcaggtaaga aaagtgcatg
    13321 agttcttctt cattgacaaa gatgacaaag gttggtggtt tggttgccac ttgggtcgca
    13381 tagaaaatct tgagacgttt tcctttgtct gtcggtgttg ggttgatggc aatggcatcc
    13441 atgatgacat cgttcaagac agctgatgga atacgtgtat tttgactttc gctgatttgc
    13501 ttaatcatct caggaagttt gtggagacgt tgcttggtta aagctgatac aaagataatc
    13561 ggtgcgtaag gcaggtattg gaactgctca cggatatctt cttcccagtt tttcatagtg
    13621 tggttatctt tttcaagcgt atcccacttg ttgaccacga taatcatccc tttaccagct
    13681 tcatgggcaa atcctgcgat acgcttgtcg tactcacgaa tgccttcttc cgcattgatg
    13741 accatcaaga ccacatctga acggtcaata gcacgcatgg cacgcataac agagtatttc
    13801 tcagtatttt cataaacctt accagactta cgcataccag ccgtatcaat catggtaaac
    13861 tcttgaccat ctgtatctgt aaagtgggta tcaatggcat cacgagttgt tccagcaaca
    13921 ggactagcaa taacacggtc ttctcccaag atagcattga tcaagcttga ttttccaacg
    13981 ttaggacgac caatcaagct aaacttaatg acatctggat tttcttcctc atattcattt
    14041 ggaagatttt ctacgatcgc atctagcaca tcccctgtac cgattccatg gacagatgag
    14101 ataggcaatg gttcacccaa accgagagca tagaaatcat agatatcatt tctcatctca
    14161 gggttgtcca ccttgttgac tgcgaggata actggtttgt gggtcttata aagcttacga
    14221 gctacgtatt cgtctgcatc agtaattcct tccttaccag acacgacaaa aacgataaca
    14281 tctgcttctt ccatggcaat ttctgcctgg tgcttgattt gttccatgaa aggagcatcg
    14341 acatcatcaa ttcctcctgt atcaatcatg ctaaaagaac gattgagcca ctcacccgtt
    14401 gcataaatac ggtcacgtgt cactccttcg acatcttcta caatggagat tcgctcacca
    14461 gcgatccgat taaatagggt tgatttccca acattgggac gtcctacaat ggcaatagtt
    14521 ggtagggcca taatttctca ctttctacaa taatttcttc tgttcaagat tttttctagt
    14581 tgagcttggt tcagcttgac caaactgttc tgctaggcgc tgactccagc ttgtggtcgc
    14641 acgcgcccca gcatagtcag cctgaacacg gtcataagct tggattgcct cagttgactg
    14701 ttcttggtat tcttcctcaa agacaacatt ctctagtggc agtcttggtt tcatatcatg
    14761 atgttgattt ggcacaccca gtgccatccc aaagacagaa taggtgtagt caggtaggtt
    14821 aaagagctct gccacttctt cagacttgta tcgaaccaaa ccgataatca caccaccata
    14881 gcccaagctt tcagctgcca acaaggcgtt ttgtccagca agagctgcat cgaccgaact
    14941 aatcaagaga ccttccacac cttggggttg gaaggtgtcg gtatgaagtc gggctccctt
    15001 ttctgctcgg ttcaaatctc cgacaaagag aaggaaaaca gcagactggc gaatggcttc
    15061 ttgaggtacc aattcataca aggcatcttt cttctcttga cttcgtacca caatcacaga
    15121 gtaggattgg aaattcttcc aagatgatgc catctgggct gctgtcaaaa tctcatttaa
    15181 gtctacttgg ggaatttctt gctctttaaa cctgcgcact gaagtatgag ccttcatcaa
    15241 tttaatggtt tctgtcatcg acggtttact ccttctaaac gagtctcctc agccaaataa
    15301 cggatgcgtt ccatgacccg tctggcttcc caggtttcgt catttccatg tttcactttc
    15361 gcaaaatgct tctccaaatc ttcaaagttg aagttggatg tgaaaaaggt cggtaaattt
    15421 tcctgcatcc gatattggag aatgacctgc aggatttcgt cacgcaccca aacggttgat
    15481 tgctcggcgc caatatcatc taaaatcagg acctcagaca gcttaatctc atccaccaag
    15541 gtcttaacat tgccatcact gatagcattt ttgacatcaa tgacaaagct aggatagtgg
    15601 aggagagtgg atgatacacc acgtttttct gataaatcat gagctagggc agccaccatg
    15661 aaacttttac ccacaccaaa gtctccatac aagtaaagac ctttcaaatt attggggtaa
    15721 tcgttaacaa attctatcat tctttttaga acagttaagc gctgaacatc atcacgataa
    15781 acatctaaaa aactgacatt tttcaggcta gatggaaaat taattaagtt gagacgtttc
    15841 ttgatagccg cttctttttc agctgcgatt agttcaggag tttcttcata agaaacatct
    15901 gcatagccat ggttcatgac taatataggc ttgtagcctt tggcaatata atctgtatct
    15961 cctcggagga atttatctct ctcagtgatg tattggttaa acttggaaat actacggttc
    16021 aactcgtcct gattgaggga ttcttgctgg acaaaggccg caacatcagg atccttcatg
    16081 attttctgaa ctaaatcttg atagtgaaaa cgacttggtt gacgtttgag tacatctccg
    16141 acactttcca tctaatcacc tccgttatct aattttgcta ataattctag ggtttggcgt
    16201 tccatctctt ctaattcctc agcggatgac gtatttttat attcaggatt actccattta
    16261 ggaatattgg tttttgctgg ggcagtctga ttctgttttt gtgtttttgc tttctgttct
    16321 cgctcacgga tgcgcaagac tgccttttct gccgaatgaa tcttttgata ggcatagtca
    16381 ttggctacct tcatggcata tttctcattg atatttgccg aatcgacctt attaaaggtc
    16441 aataaaagaa tgatattgat gacttcgtcc agcaagccca agccagccat ctgttgcaag
    16501 agttctcttt ctgtttgggt aatggttccc ttgcgtgttt gcttgatttc tgccaagaac
    16561 tgcagggcag ttttactttt ggcttctttg ataatggttg tttccttaag actaaagtca
    16621 gaggaaactg gtttttgagc aattttttcc cgcatgcgtt tggttgaaat aacctgagaa
    16681 acagctgttg acttggccaa ttgataggtt tcaaaccaag tccatttctt ctcctcggca
    16741 atagcaaaga ggtttaagac atcggactgc tcatccgcaa aacgaagtcc atctcgagcc
    16801 atcagctggc gaaaatggtc caagtcaaaa tcgttggcca ctttcttctt gagaccaagg
    16861 tcttcttgac tgcctagttc tgccaattct ggaaagactt gattgagtga gacaggtatt
    16921 tcttcaccat cagcactttc aactttcaaa tcctccacag ctacatcgcc aatctttttc
    16981 tctaagagtc tgcgataaac aggatgctcc aagaagtctt gactagatag aggagcatgg
    17041 aggactagct gataaacatc ccccttttga tagagggtca agagattaaa agcagataag
    17101 attttcaatg attttatcag tctatccatc ccaaagttaa gatggttgag aatgcttgaa
    17161 aaaagatatt cctttctacc attatcccaa aaactgattg tataaagata aaggctcagt
    17221 gcctcctgac cgataatcgg gaggtagcac tgtaccagag atgaggtatc ttgcgacacc
    17281 cgattattct ttagataaga aaaacggtca attggcttca tttatctttc ctttttcttt
    17341 ttagaggact gggtgatttg ttggagcaag ctctctaact cactgacatc cttaaaacta
    17401 cgatagacac tagcaaaacg tacataggta atctcgtcca attcagccaa ctcctccatg
    17461 acgagtgaac caatgtcctc actttgaatt tcattttcat ttcgaccacg gagtttctgt
    17521 tcgatacgat tgactaccat gttgatttca tcacttgaca caggacgttt ctgggctgag
    17581 cggataatcc cattaaagat tttatctctg gagaattgtt cccgtgtgcc atctttttta
    17641 acaaccacta aggttctttc ttctactcgt tcgtaggttg taaaacggtg ttggcattcg
    17701 tcgcactcac gtcttctacg aatggtgttc ccttcttctg cttggcgact atcgataaca
    17761 cttgacttgg tagccccaca ttttggacaa cgcatccttt ccctccttat cgttttcttt
    17821 tcattatacc attttttaag cgattcccaa aacaattctt ctttttgctt gacaagtttt
    17881 ttgttttgtt gtattattta attaagacaa aagggtaaaa gaaaggagac taagatgtcc
    17941 tggacatttg acaacaaaaa acccatctat ttacagatta tggagaaaat caagcttcag
    18001 attgtttccc atacactgga acccaatcaa caacttccaa ccgtgaggga gctagctagc
    18061 gaggctggtg tcaatcccaa taccatccaa agagccttat cagaccttga acgagaagga
    18121 tttgtctaca gcaagcgaac aactggacga tttgtgacta aggataagga gctaatcgct
    18181 cagtcacgca aacaattatc agaagaagaa ttggaacact tcgtttcctc catgacccat
    18241 tttggctatg aaaaagaaga actaccaggc gtagtcagtg attatattaa aggagtttaa
    18301 gcctatgtca ttactagcat ttgaaaatgt atccaaatca tatggagcaa caccagccct
    18361 tgaaaatgtt tctcttgaca ttccagctgg aaaaattgtc ggccttcttg ggccaaacgg
    18421 ctcaggaaaa acaaccctga ttaaactaat taatggcctc ttacaaccag atcaaggacg
    18481 tgtcctcatc aacgacatgg acccaagccc agcaaccaag gccgttgtag cttatttgcc
    18541 tgatacgacc tatctcaatg agcaaatgaa ggtcaaagaa gccctaacct acttcaagac
    18601 cttctataaa gatttcaatc ttgaacgcgc ccatcatcta cttgcagacc tgggcattga
    18661 tgaaaatagt cgtctcaaga aactatcaaa aggaaacaaa gaaaaggttc aactgatttt
    18721 ggttatgagc cgtgatgctc gtctctatgt tttggatgaa cccattggtg gggtggatcc
    18781 agcagcccgt gcttatatcc tcaataccat tatcaacaac tactcaccaa cttctaccgt
    18841 tttgatttct acccacttga tttctgatat cgagccaatc ttggatgaaa ttgtcttcct
    18901 aaaagacgga aaagtcgtcc gtcaaggaaa tgtagatgat attcgctacg agtcaggtga
    18961 atccattgac caactcttcc gtcaggaatt taaggcctaa gcaaaggaga ttatttatgt
    19021 tttggaattt agttcactac gaatttaaaa atgttaacaa gtggtattta gccctctacg
    19081 cagccgtgct agtcctttct gccctcatcg gaatacagac acaaggcttt aaaaatctac
    19141 cttaccaaga aagtcaggct actatgctac tttttctagc tacagtcttt ggtggcttga
    19201 tgcttacact tgcgatttca accattttct tgattattaa acgcttcaaa ggtagtgtct
    19261 acgaccgaca aggctatctg actttgacct tgccagtttc tgaacaccat atcatcacag
    19321 ccaaactaat cggtgccttt atctggtcat tgattagcac cgctgtattg gctctaagtg
    19381 ctgttattat tctggcttta acagctccag aatggattcc tctttcttat gtgattacat
    19441 ttgtagaaac acatctccct cagatctttc ttacaggtat atccttccta ctaaatacca
    19501 tttcaggaat cctctgcatc tacctggcta tttccattgg acagcttttc aatgaatacc
    19561 gtacagcact cgctgttgca gcctacattg gtatccaaat cgtcattgga tttattgaac
    19621 ttttcttcaa tcttagttcc aatttctatg tcaattcact ggtaggactc aatgaccatt
    19681 tctatatggg agcaggtata gccattgtta aagaactcat attcatagct atcttttatc
    19741 tcggaaccta ctacatcttg agaaataagg ttaatttgct ttaaataatt tttacctaga
    19801 tatgtaacat actcatagaa caaaagagac caggcaaaaa gtctttaaaa ttagaaaacg
    19861 catagtatca agtgttaaaa atccttgata ttatgcgttt tttgtgagct gacttatttc
    19921 ctttcgctat atcgcaaaat gaaataagaa cggaacgatg ggattttgga attcaaatca
    19981 atttataaga atgttttaga agtaatatta tcctattcca gattcagttc actatacaat
    20041 tgagttttca agcaacctgt ttacataatg tgtacataat taggttcgtg attccaccct
    20101 tttcaccttt aaaaacctcg ctttcgcaag gctcttctat ttataagata aggcacgttt
    20161 aaaggttttc caaatcccta aatcatccgt ttgaagaacg agactagcat acatgcgtcc
    20221 gataaatcct gttgctacca ccgcaaaaat cactgtaata gcaagtgaaa tccatgcttc
    20281 tgctcccccc gcatagccat taatcgttcg aaacggcata aagaaggtcg aaataaaggg
    20341 aatataagaa ccaatcttca agaggagatt gtcaccagct gcacctagag ctgtcactcc
    20401 aaaaaaacca cccataatca aaatcatcaa aggcgacaag gctttccctg agtcctcagg
    20461 acgagaaacc atagatccta ggaaggctgc caagactacg tacatgaaaa gactgatcaa
    20521 aataaagagc aaggtattca gtgagatagc atctcccaag tgatccaaaa taccagactg
    20581 agccaagaat ggcaaatctt taaagagcaa aacggcagcc agaccaccta caacatagat
    20641 cccaatatgc gttaaaatca ctagaaacag agccatcatc cgcgcataga aatagtgact
    20701 tgcccttatg ctagaaaaaa cgacttccat aattttggtg cctttttcac tggcaacttc
    20761 ctgagctgtt acacccgcat aggtaatcag aatcatataa agaaagaatc ctaaggcacc
    20821 tgctgcaatt gtttgaataa actttttatt ttccttggct tcatcaatct tttctgtgaa
    20881 ttgaattgtc tgcgctaagc gtttttcctg ctcttgagac aaggaagcag ttgaacgatt
    20941 aagctgattt tgcagttcat tgagtgtacc tgtaacctca aatttaattc cattttcaag
    21001 cgatgtttcg ccatgataaa ctgcctttag aacactatct tcttgatcaa tggtcaaata
    21061 accttttaat ttttcttctt taattgcttc tttggcactt gcttcgtctt tatagtcgaa
    21121 gttaacacca tttacattct tcagtccttc tgctacagat ggcactgttg tcactactgc
    21181 cactttatta tttttagcca tagaagaacc ttggatatgc ccaattccta cagagattcc
    21241 taaaaagagg aacggcgaaa tcaccataaa gaagaaactc catgactcga catgtcgaag
    21301 ataggtttcc ttgattacaa cccacatatt tctcatactt ccactcctga ttctagttta
    21361 aagatttcat cgatagttgg cgcttgttgg tcaaatgttg cgatatattg accttgagtc
    21421 aagattggga agagttccct tccagcgctc tcatcctcca aaatcaattt ccaactgcct
    21481 tgtttggtca agctcacctg tttgacatga ggaagatttt ccaattcttc cttgcttcgt
    21541 tcacttgaaa caaagagacg cgttttcccg tattgattgc ggacatcctg aactggtccg
    21601 tgcaagacca cacggccatc tcggatcatc agaatatcgt cacaaagttc ctcaacattg
    21661 gtcatgacat ggtcagaaaa gataatggtt gctccgcgct ctttttcctg aaaaatgact
    21721 tgtttgagca attctgtatt aactgggtcc aatccactaa aaggctcatc caagataatc
    21781 aggtctggtt catgaatcag agtaataatg agctgaatct tctgctgatt tccttttgac
    21841 agactcttga ttttatctgt cagctttcct ttcacttcca acctcttcat ccattgaggg
    21901 agtttttctt tgacttcttt ggcatccatg ccttttagag tcgccaagta gcgaacttgt
    21961 tcaagaactg tcaatttagg catgagactg cgttcttcag gcagataacc aatccgagca
    22021 taggtctcct gacgaatatc ctgaccatcc agaccgattt ctccctgata ttctaggaat
    22081 ttcaaaatac tatggaaaat cgttgttttt ccagcaccat tttttccgac tagtcccaaa
    22141 atacgacctg gtcgcgcttg aaagtcaata ccaaacaaaa cttgcttgga gccaaaactt
    22201 ttctctagac ttcttacttc tagcatcttt cacctccgaa atttcttgca ctcattatac
    22261 tcctttttga tagcctttac aatgtttttg tccattttta gaagactatt gctgtgtaaa
    22321 atatggcctg gagcactttt atactcaatg aaaagcaaag agcgaactag gaagctagcc
    22381 gtaggctgct caaagtacag ctttgaggtt gcagataaaa ctgacgaagt cagctcaaaa
    22441 cactgttttg aggttgtgga tagaactgac gaagtcagta actatatcta cggcaaggcg
    22501 aagctaacgt ggtttgaaga gattttcgaa gagtattagt gataaatcca ttatacagta
    22561 gcaaactcaa tttatacctt ccgctcctca actgtctatt tttaatcctg aattgttatt
    22621 tgagtaactc ctttttcctc ataaagtttt cttcctctaa aacttctgga aaaaagcgaa
    22681 tagtttcaga caacattttt ataagaaaca agttcatctg tcatttcaag aaggagtaat
    22741 cctttatcta ctaatggacg gaacggaatt caaccgcttg tccgatatat tttctaagga
    22801 ttatatagta aaatgaaata aaaacaggac aaatagatcg ggacagtcaa atcgatttct
    22861 aacaatgttt tagaagtaga tgtatactat tctagtttca atctgctata tctattatgc
    22921 acaccactat aggatctaat aaaaatcaca acaagttcat tcatagatgg ttacctcagg
    22981 gaactaagaa aacgactaca aaggaagtcg cattcatcga aaagtggatt aacaactatc
    23041 ctaaaaaatg cttgaactac aagtccccca gagaagactt ctggatgact aacttgaact
    23101 tgaaatttag caataattaa ttcaccatct aactatattt agtaattatt tcagaactga
    23161 ttaatattaa aattaactaa caattcaaag gattcatact agccataaat tacgtccatc
    23221 agagagagac tcttactact tttagatttt agtctttcta gcttcagaat acatctaaac
    23281 tttagggaaa atgactattc gaaagcgcga atgcctcaaa attatctcag ataagctatt
    23341 cgaaacttag aatgctttta aatttatgga attgcgatta ttcgaaacct agaatgcata
    23401 taacctttag ttgacagacc tattctaagt ctcgaagggc tatttacttt ctattcctta
    23461 tcaaaaaaga ctcattcccc ctttctcctc caaaatatgg tatagtagaa atatactatc
    23521 tatgaggagt ttacatgtca caggataaac aaatgaaagc tgtttctccc cttctgcagc
    23581 gagttatcaa tatctcatcg attgtcggtg gggttgggag tttgattttc tgtatttggg
    23641 cttatcaggc tgggatttta caatccaagg aaaccctctc tgcctttatc cagcaggcag
    23701 gcatctgggg tccacctctc tttatctttt tacagatttt acagactgtc gtccctatca
    23761 ttccaggggc cttgacctcg gtggctgggg tctttatcta cgggcacatc atcgggacta
    23821 tctacaacta tatcggcatc gtgattggct gtgccattat cttttatcta gtgcgcctat
    23881 acggagctgc ctttgtccag tctgtcgtca gcaagcgcac ctacgacaag tacatcggct
    23941 ggctagataa gggcaatcgt tttgaccgct tctttatttt tatgatgatt tggcccatta
    24001 gcccagctga ctttctctgt atgctggctg ccctgaccaa gatgagtttc aagcgctaca
    24061 tgaccatcat cattctgacc aaacccttta ccctcgtggt ttatacctac ggtttgacct
    24121 atattattga ctttttctgg caaatgcttt gacacgtaaa aaatccgttt ggtttcccaa
    24181 gtggattttt aaagcgtaga ttaactatag cttgatacta aatatacttt ggtatggaaa
    24241 ttatgcatat ttttcgatag tgaggcgagg acttacctag cctttccgcc gtgatagaaa
    24301 cacctgaaat ctaatggttt caggtattcg gaaactttga gacactaggc tcaaagttta
    24361 ggtatggaat ttcgaagaaa gtcgctaccg tccgtaatca cttaaggaaa ggctcaaaaa
    24421 tattgttttc aaccacaaaa tccgtttggt ttcccaagcg gattttgtgc tttattttga
    24481 aacttctttt gcaagaacaa agttcccaag tgtggcagaa ccatttcctg cgactgctgg
    24541 cgtcacgata tagtcacgca catctggtac tggtaggtaa ccattaagaa gagatgtaaa
    24601 tttctcacgg acacggtcca gcatatgttg ttgagccatg acccctccac caaagacaat
    24661 cacgtctggg cggaaagtca ctgtcgcatt aaccgcagct tgagcgatat agtaggcttg
    24721 aacatcccaa acagggttgt tgagttcaat attttcccca cgtacacctg tacgagcttc
    24781 caaacttgga ccagctgcat aaccttctag acatccctta tggaaaggac aaacaccctt
    24841 aaactctttt tcaatatcca ttgggtgtct agcaacataa taatgaccca tttcagggtg
    24901 acccacacca ccgataaact caccacgttg gatgacgcct gcaccgatac ctgtaccgat
    24961 tgtgtagtaa accaagtttt cgatacgacc accagcattg ttacgggcaa ccatttcacc
    25021 gtaagcagag ctgtttacgt ctgttgtgaa gtacattggc acgtttaggg cgcgacgaag
    25081 ggcaccaagc aagtctacat ttgcccagtt tggttttgga gtcgtcgtga taaagccata
    25141 agtttttgag tttttgtcaa tatcaatcgg cccaaatgaa ccaactgcaa gaccagcaag
    25201 gttatcgaat tttgagaaga actcaatggt tttatcgatt gtttcgattg gagttgttgt
    25261 tggaaattgt gttttttcta caacgttaaa gttttcatca ccgacagcac agacaaactt
    25321 tgtaccgccc gcttccaagc ttccatataa ttttgtcatg ataaacctct tgtttttatt
    25381 ttctttatta tagcatactt cgaaagtcta aatgtctcta ttttttagat tttcctctgt
    25441 aaatcttact atctaataaa aacgaacaaa catgtcattt gttcgttttc acattagaga
    25501 ggattgatta gattttcact tcgatcacag catccccctt cgaaactgaa cctgttgcga
    25561 ctggagctac tgaagcgtag tcagctgtat ttgtaacgat aaccattgtt gtatcatcaa
    25621 gtccagctgc agcgattttg tttgagtcaa atgttccaag aacatcgcca gctttcacct
    25681 tattaccttg agcaactttt gcttcaaaac cgtcaccgtt catagataca gtgtcaatac
    25741 caacgtgaat caaaacttca gcaccatttc ttgttttcaa accaaaagcg tgccctgttg
    25801 gaaaggcaat tgaaacttca gcatcagcta gtgcatagac cacgccttga cttggtttca
    25861 cagcgatacc ttgtcccata gctccacttg agaagactgg gtcattgaca tcagcaagag
    25921 cgacaacatc accgacgata ggagttacaa gtgtttcatt ttgaagagct gctggcgcaa
    25981 cttcttcttt ttcttcagcc acttcagctt gttttgcagc tgcagttgcg tctacttcat
    26041 cttcgtaacc aaacatgtaa gtaagagcaa aaccaagggc aaatgataca gctaccataa
    26101 gaaggtattg tggaagttgt ccgttaccaa cataaagcat tgtaccaggg atgatggtga
    26161 taccattacc agtaccagca agtccaagga tagaagccaa tccaccaccg attgcaccag
    26221 caatcaatga aaggaagaat ggtttacgga agcgcaagtt caccccgaag atagcaggct
    26281 ctgtaatacc taggaaggca gaaagagcag ccgggaaagc aagtgttttc agttttggat
    26341 tttttgtttt aacaccaacc gcaacagtag cagcaccttg agctgtcata gcagctgtga
    26401 tgatagcgtt gaatgggtta gcatggtcag cagcaagtaa ttgcacttca agcaagttga
    26461 agatgtggtg cacacctgac acgacgatca attggtgaac cccaccaatc aagaaaccac
    26521 caagaccaaa tggcatgcta agaatcgctt ttgtagcaat aaggatgtag ttttcaacaa
    26581 cgtggaaaac tggtccaatg acaaagagtc caaggataga catgaccaaa agtgtcacga
    26641 atggtgttac caagaggtca atgacatctg gaacaacctt gcggacagct ttttcaaatt
    26701 tagctccgac aaccccgatg atgaaggctg gaagaacgga accttgcaaa ccaacaacag
    26761 ggatgaaacc aaagaagttc atcgctgtta cttcaccacc ttgagcaact gcccaagcgt
    26821 ttggaagtga gccagagaca agcatcatac caagaacgat accaacggca ggatttccac
    26881 caaatacacg gaaggttgac cacacaacca aacctggcaa gatgatgaag gctgtatctg
    26941 tcaagatttg tgtgtaagtt gcaaagtcac ctggaagtgg catttcaaga gcgttgaaaa
    27001 gaccacgcac acccatgaag agacctgtcg ctacgataac tgggatgatt ggaacgaaaa
    27061 catcaccgaa agtacggata gcacgttgga accagttccc ttgtttagca acttctgctt
    27121 tcatgtcatc cttagatgat gttggtaagc caagtacaac aacttcatcg tacattttgt
    27181 taactgtacc tgtaccaaag ataatttggt attgccctga gttaaagaaa gcaccttgaa
    27241 ctttttccaa gttctcaatc acttctttat tgattttctc ttcatctttg accatgacac
    27301 gtagacgagt cgcacagtgg gcaacactat tgacattttc acgtccgccc aaggcatcga
    27361 tgactttttt tgcaatttcc tgattgttca tttgcaaaaa tctccttata taacattttg
    27421 ttcttgtttg aaagcgattt tattcgccct tacgactatt attttatcat gttttaaaaa
    27481 tatgtcaagc gttttgcaga aaaaatattc tatccactta gtgggcaagt tttagattga
    27541 ttgtttttga ctgtttcatc aggaattcct tgaaaaataa gtttgaaacc ttggttaaaa
    27601 agtcttttat ttcattatct ttcacatttt cgtaaaaatt tgattgattt cctgtattta
    27661 ttttatgata atcgtttgac agtttttcct cttttttaac ataaaaggct tgcatttttt
    27721 atcgaaaaca gttactatta aaagtgataa gatttttgga ggaatgaatg gaatggacaa
    27781 ctgagcgtcg ttacagactt tatcaagatt ggacgcaaga agaaattcaa catataaagg
    27841 aaaatatggc acaatctcca tggcatactc attaccatgt tgagccaaaa acaggacttc
    27901 tcaacgaccc aaatggcttt tcttactttg atggcaagtg gatcctcttt taccagaatt
    27961 ttccttttgg tgcagcccac ggtttgaaat cttgggcaca gctagaaagt gatgatttgg
    28021 ttcactttaa agaaactgga atcaaagttt taccagatac tccattagat agccacggtg
    28081 cctactctgg ttctgccatg caatttggcg ataacttatt cctattttat acaggaaatg
    28141 ttcgcgatga aaactggatc cgtcacccat accagatcgg tgctttgatg gacaaggagg
    28201 gtaagattac aaagattgac aagatcttga ttgaccagcc agcagactct actgaccact
    28261 tccgcgatcc acaaattttt aactttaaag gtcaatacta tgctgtcgtc ggtggacagg
    28321 acttggagaa aaaaggcttc gtccgtctct acaaggctgt caataacgac tacacaaact
    28381 ggcaagcagt tggcgacctt gactttgcta acgaccgtac tgcctacatg atggaatgtc
    28441 ctaatctggt ctttgtagag gaacatcctg tccttctcta ctgtccacaa ggattggata
    28501 agaaagttct agactacgat aatatctttc caaatatgta taagattggg gcttcctttg
    28561 accctaaaaa tgccaaaatg gtagatgtgt ctcaacttca aaacatggat tacggtttcg
    28621 aagcctatgc aactcaagcc ttcaacgctc ctgatgggcg tgctctagca gttagctggc
    28681 ttggtttgcc agatgtttct tacccatctg accgttttga ccaccaagga accttctctt
    28741 tggtcaagga actcactatc aaagacgaca agctctacca gtatccagtc gctgctatta
    28801 aggaccttcg tgcttctgaa gaagccttct caaaccgttc ccaaaccaag aacacttacg
    28861 aacttgaact caacttggaa gctaatagcc agagcgagat tgtcttactt gctgataaag
    28921 aaggtaaggg actttcaatc aactttgacc ttgtaaacgg tcaagtgaca gtggatcgta
    28981 gccaggctgg agaacagtat gcccaagaat ttgggacaac tcgttcttgc cctatcgaga
    29041 atcaggctac tactgctaca atcttcatcg ataactctgt ctttgaaatt ttcatcaata
    29101 aaggagaaaa agtattttct ggtcgtgtct tcccacatgc ggaccaaaat ggtatcctga
    29161 tcaaatctgg aaacccaact ggaacttact atgaattaga ttatggtcgc aaaactaact
    29221 gatgtcgcca aacttgcagg cgtcagtcct actaccgttt ctcgggttat caataaaaaa
    29281 ggatatctat ctgagaaaac catccaaaaa gtcaatgaag ccatgagaga attaggctat
    29341 aaacccaaca acctggctcg tagtctgcaa ggaaaatcag ctaagttaat cggcttgatt
    29401 ttccccaata tttccaatgt tttctatgca gaattgattg ataaattgga acaccaactc
    29461 ttcaaaaatg gttacaagac catcatctgc aacagtgaac atgattctga gaaggaacgc
    29521 gaatacatcg aaatgttgga agccaatcag gtagacggca tcatttctgg tagtcacaac
    29581 ctaggaatcg aagactacaa tcgtgtgaca gcgccgatta tttcctttga ccgaaaccta
    29641 tcgccagaca tccctgttgt ctcctctgac aactatgctg gtggggttct tgctgcccaa
    29701 accttggtca agacaggtgc ccagtctatc atcatgatta cagggaatga caattccaat
    29761 tcgccaaccg gactgcgcca cgctggtttt gcatccgtac tcccaaaagc tcctattatc
    29821 aatgtttcca gtgacttttc tcccgtcaga aaagaaatgg aaatcaagaa tatcttgacc
    29881 cgggaaaaac cagatgccat ttttgcttcg gatgatttga cagctattct ggtcattaaa
    29941 atcgctcaag aattgggcat ttctgtccca aaagagctca aggtcatcgg ctatgatggg
    30001 acctacttta tcgaaaatta ctaccctcaa ttggctacta tcaagcaacc tttggaagag
    30061 attgcttgtc tcactattga tcttctcttg caaaagattg aaggcaagga agtcgccaca
    30121 actggttact tcttaccagt tacgctatta ccaggaaaaa gtatttaaac acaagaaaac
    30181 tcagaccgat tcgtctgagt ttttatgatc ttaaattttc gagatagcgc tgggctgtct
    30241 ctaggttaaa ggttttatct gagatgaggc gctctactag gggagcaact tcagattcac
    30301 tagccccagc taggagagct agggatttgg cctgtagttt catgtggcct tgctggatgc
    30361 ccgtacttac caaggctttg agggctgcaa aattttgagc aagaccgatg gacacgataa
    30421 tctgggctaa ttctctggca gaaggatttc ctagtagatc atgactgaga gctacacgtg
    30481 ggttgaggcc gatagagcca cccttagtcg ctacaggcat gggcagggtc atctcaccga
    30541 ccaattcttc tctttcaagg tccagcgtcc agcagctaag accttgatag cgtccatctc
    30601 gactggcaaa ggcatgggcc ccagcttcga tggcacgcca gtcattacca gtggcaatca
    30661 aaatcgcatc aataccatta aaaattcctt tattatgagt agcagctcgg taaggatcag
    30721 cctgcgcaaa ctgactagcc aacgcaattt tctccgcaat ctctcgtcct tgatcctttt
    30781 ggcggctcaa gtagcgaaag gcgatgcgac agcttgcagt caccagagaa tcagtcgcgt
    30841 agttggacag gattcccatg agactctgtc cctgactgag ttcttctaag actggtttca
    30901 aggcttccag catggtgttg agcatattgg cacccatggc ttcctgggta tcgacatgaa
    30961 tataaacaac gagaaagtct ggttcgcctt ttatctgctc gacatgcaga tcacgcgccc
    31021 cacccccacg tttaacgata gaaggatagg cttgattggc aagctccaag agctccgctt
    31081 tcttgctggc aatcttctct tgcgctagtt taggattagc aacttgataa agggctacct
    31141 gcccaatcat ctggcgctga tggacttgtg cagtaaaacc acctgcacgc ttgatgattt
    31201 tgctggcata gctggccgcc gcaaccacag agggttcttc tgtcacatag ggaacggtgt
    31261 attcctgacc gttgacaagt acctccggaa ccagtgaata aggcagagaa aaagttccca
    31321 ctacattctc actcagctgg tctgccacag tcacgctcat ctgttcatcc ttctccagac
    31381 tagcttgtct ctcaggacta aggagcgcct gagcttttaa cagctcgagg cgctcttggt
    31441 atgatttttt agaaaatcca ttccaactta tcttcattat ttttcaacct tgctataacg
    31501 gcgttggtgg tcgagaattt caaccaaggc aaaatcttga ttttcatagc cagcaaactg
    31561 ggcagagttt gtttcatcca agtttacttc ctcaaaaaag accttttcat agtctgcaac
    31621 ggatagggca gttcgttggt tgagcttgtt caaacggtct ttatccaaat aagcttcata
    31681 tccttcaacc aattcaccac tgaagaactc agccacagct ccacttccgt aactataaag
    31741 ggcgatttta tccccagctt tcaagctatc tgtattttcc aagagagaca aaagtccaag
    31801 gaaaagtgaa cctgtgtaga tattccccac cttttgactg tagagaatag actggtcaaa
    31861 atgcttttgt aagaggtctt ttttctcttg aggcaggctc ttatccatga tttttttcaa
    31921 gccttttagc gctaatttag gataaggcaa gtggaaacaa acagccgcaa aatcatccaa
    31981 agtaagctgg tagcgttttt gatattcaag ccaagtcgtt ttcaaactat ccaagtattg
    32041 ttgggtagaa tagacaccat ttacataagg agttgtcgag taatttggtc gccagaaatc
    32101 catgatgtca cgggtctgag ctacattgtc attattaaag gccatcatgc gtggattttg
    32161 tgtaatcaac atagccacac ttccagcacc ttgagttggt tctcccggag tttcaatacc
    32221 atatttggca atatcactgg caatgaccaa gaccttggac tccggagaat tttccacatg
    32281 caatttggca taatggaggg cagctgtcgc cccatagcag gcttctttaa tctcgaaact
    32341 acgagcaaag ggctggatgc ccagcaagcc atgcacaaag acggccgcag ccttactctg
    32401 gtcaattcct gactcggtag ccacaatgac catgtcaact tcttgtcttt cttgctcagt
    32461 taaaatagag tcactagcac tggccgccaa ggtcacgatg tcctcagtta ggggcgcaat
    32521 actcaattcc ttgagtaaga gtcctttact taatttttca gggtcaattc ccctcgcttc
    32581 tgctaagtct tgtaatttca agacatattg actggtcgca aaaccaatct tatcaatacc
    32641 gattgtcata tttacctctg ttttatcatt catgtaaaaa atcgttctat actattttat
    32701 cacaaatggc agtaaaagag agaaaaaaga cttgattcac caaatcaagc ctcttattgg
    32761 tcatcatttt aaagaatgat tagttgctag agagttcacc gatataagta gctttataag
    32821 ctccattcac agttatcagc tcctggagga tcaaatttcc tgagtaagtc cttcccatct
    32881 catctacaaa tttttgataa aactgactgg tcggaatttc tctgacatcc ttatcaaatg
    32941 tcttgtcaag tgttttacta accttctcag caatcaattg atgctcttgc catccacttt
    33001 gaaactctga gccccaacta gaaaccatga ctgggataaa caacaaggtc agtagactta
    33061 cagacaataa ggaaaatagt agacttcctg caaaactaga atcctagttc atgattgata
    33121 atgccagcaa tcaaattcat tcgtaatccg aagcgtttac gatgatttcg atagattgtt
    33181 gaaaacattt taaacgtttt tactttggca aagatgttct caaccttgct tctctccttg
    33241 gatagcgcat ggttacaagc tttatcttca gctgttagcg gcttgagttt gctggattta
    33301 cgtggagttt gtacttgagg atatatcttc atgagccctt gataaccact gtcagacaag
    33361 attttaccag cttgtccgat atttctgcga ctcattttga acaacttcat atcatgacaa
    33421 tagttcacag cgatatccaa agaaacaatt ctcccttgac ttgtgacaat cgcttgagcc
    33481 ttcatagcgt ggcatttctt tttaccagaa tcattcgcta attctttttt agggcgattg
    33541 atttgtactt ccgtcgcatc aatcattacc gtgtcctcag aactgagagg agttcttgaa
    33601 atcgtaaaac cactttgaac aagagttact tcaacccatt ggctccgacg gattaagttg
    33661 ctttcgtgga taccaaaatc agccgcaatt tcttcataag tgcggtattc tcgcacatat
    33721 agaaagcgtt gttaatttat ttatctcatt tttcagaaaa ttctttcatt tgtgtaaagt
    33781 ctacgatact cgatgtgttt ttatataatg atacagtctg agaatcactg ttccgctagc
    33841 cattccaata gagattacca aagccaacat gacaaccaag gtcgcacttg ccagtgcttt
    33901 attatagtcc cctgtcacaa aaaaggcagt tgttcggtag gagagataac ctggaaccag
    33961 cggtgccaaa atggccaaga taaagaccac agcaggtgtc ttataaagaa tacttaaaat
    34021 ctggctgaca caagaaccaa taatggctgc aatgaaggta gctacaatga cattggtcgg
    34081 ctccttgagc aagagataga ttagccagac agtcatgccc aaaatccctc caggtaagag
    34141 catagaccgt tgcacattga gtacgattaa aaaagtgata atggcaagaa aacttgctac
    34201 tgcttgtaat aaaaaggttg ttagtgtcat attagttcat caataccaag gcgacagaag
    34261 ttcctgcccc taaagcgagg gtaatgagca gggattcaaa catcttactc ataccagagt
    34321 ttatgtggtt ggtcataata tcacggaccg cattggtcaa ggcaatacct ggtacaaacg
    34381 gcatgaccgc accagctata atcaaatctg ccgttgaagg aaaacctgtg tagcgagccc
    34441 aaaactgggc aattatccca aagacaaagg ctccagcaaa ggctgtcaca aagggaattc
    34501 ggataaattt ttccacatag agggaaaagg caaaaccaaa taaggtcgcc actcctgccc
    34561 caagtgcgtc gtagatattt ccgctaaaca taactgaaaa gaaaggagcg ctaaaggtcg
    34621 cagccagagt tacctgcaac ttagtatagg gaaggggttg agcttgcaag gccgtcaatt
    34681 gcttaaaggc tgtttctaaa tcaatctgcc ccccaaccag ctgacgagaa atctggttca
    34741 catcgcagac tttttcgatg ttataagaag aggaggtcac gcgcttcatg cgcgaaatat
    34801 tggtattttc aatagagaaa aagatagcgg caggcatggc aaggacattg caatccacaa
    34861 tcccctgcga atgcgcgatt cgaatcatgg tatcttctac acgatggatt tctgagccac
    34921 ttttaaggag aatagtcccc gctagcataa tcacatcaat gacggtattt aattcttttg
    34981 attcttccat gctttcctcc ttttatcaac tccctctatt ctatcacaaa tccggactca
    35041 aaaaaaatct ttgccatgaa atcatgacaa agattgatta ctcattttga ttatccatct
    35101 gcttgattat ccatctgctt ttaaggagta gctgaagttg ttttaggttt gtagattgaa
    35161 atcttgactc tagtcttatt gaggtctacc ttttcacctg ctctaggact ttgttcaaca
    35221 accatgcctt ctgcactacc tgcaggcgct gtcgtcactt ctacaacttc tatattagct
    35281 tccttaatcc caacaatttg aatcaaattg ttcttagtaa actccaagct ggaaccaatg
    35341 taactcggca tggcaacact tgtaactttt ttagctactg tcaagacaat ttgaataggt
    35401 ttactcacat cataggtcgt tccggcacct ggactttgtt tcataatcgt tcctggttcg
    35461 ctttcgctgg actcttcttc ctctatctta atcaaattct caggaacctt cttctgcttg
    35521 agttctgaga ttacttctgt agagttccgt ccaatatagt tccctaattg aatcgtcgta
    35581 gcttttttag ctactgtcaa aacaatttga gttgccttgc tcaagtcata ggtcgtacct
    35641 tctggtagac tttgcttcag gaccgttcca gcctcactct cattggactc ttcttcctca
    35701 attttaatca aattatctgg aacttttttc tcttttaatt ccgcaatgac atcagaggat
    35761 ttccgaccga cataattact aatttggaag gattgcttgc ctgatgagac aaccaaattg
    35821 attttcgttc cttcttttcg accagttcca gcgccaggat ctgtacggat aatccgccct
    35881 tcttccacct tttcactagc ctctgtcttc tcctcaccaa tctcaaaatt ggcttttttg
    35941 agcgttgcct tggcctctgc aactgtctga cctgccacat ctggaatggc aatggttgca
    36001 ggagttctgg atagtatcca aataagagaa gctgccacca atacaaggct ggccaacaaa
    36061 atcaggtaac gcatcttaaa tctatgtttt ttcggtgctt gtggttggta agtttcctct
    36121 gtcacagcct ggcttggggt tttgattgat ttgtgttctg tctgcgcttg aaccttagga
    36181 atagatgtca aggtactctg agaaaccttc ggcaaggtct tggtatctgc cttgctcgtt
    36241 tcatcaaaga ttaacttact ttcatttcta cgattgtagg acaagctact agacaagtcc
    36301 acatacatct ctgaaaccga gcggtagcga ttggtcaact ttttagcagt tgccttgata
    36361 ataacatttt ctaaagcctg aggtacagat ggattttctg caataacgga cggcaggggt
    36421 ttctggaaat gctggagggc aatggtcacc gcgctatccc cgtcataagg gatatggcct
    36481 gtcaacatct catagaaaat aatccccata gcatagatat cactctgcac agtcgccttc
    36541 gaaccacgcg cctgctctgg ggacaagtaa tgaactgagc ccaacatcga gttagtctgg
    36601 gtcagacttg tctctgcaaa ggctacagca atcccaaagt ctgtgacctt tgcagtccca
    36661 tctggtgtca aaaggatatt ttgaggtttc aagtccctgt gaacaattcc tctggtatgg
    36721 gccaaacgca tggctaggag gatttgtccc atgatacgga ctgcttcttc attagaaaga
    36781 ggataatgtt ccttgatata gcgtttgagg tctagtccag caacatactc cattgcaaga
    36841 tactgttgac cgtcttcctc accaatatct gttatccgaa cgatatgagg atggtctaga
    36901 tctgccatag ctctcgcttc acgctgaaaa cgagctacag ctatcgggtc cgtctggtag
    36961 ttggtcctca gaaccttcac tgccacttct tccccatcta agattaagtc tttggctagg
    37021 tagacatccg ccatacctcc tcgaccaatc tgtttgacaa tccgatagcg tccggcaaaa
    37081 atcttgccga tttggatcat tctgcatcct cctcgttcat agaaacaagg gcaaccgtaa
    37141 tgttgtctaa acctcctgca ttgttagcaa aacgaacaag tgtctccgtt ttatctgcta
    37201 aaggaatatc actggttaca atatcacgaa tctcactgcc tgaaatcatg ttggtcaagc
    37261 cgtcactatt gagcaagaga tagtcacctg actcaaggat aactgtccca aaatcaggct
    37321 gaatttcatc tttttgccca atagactggg tgataatatt tttttgcgga tgagcttctg
    37381 cctcttctgg tgtcaattga ccagccttga gcaattcatt aaccaaggaa tgatcgctcg
    37441 tcaactgatg gtattcttct ccacgaatca agccgatacg cgaatcacca atatgagcat
    37501 agatagcctg attatcaata atagcaagga cttccaaagt agttcccatg cctctgtaag
    37561 cttcatcctg accaagctgg tgaatctttt gattttcaat ttctaggtaa tgggcgaacc
    37621 attcacgcac ttcattgact gtatcgatct gggtatcaac ccaagctaca cccaggtctg
    37681 tgaccgccat ttcactagcg atattccctg cacgatgacc tcccatccca tcagctaaaa
    37741 taatcatggt acgtccagct ctattgacat agtggttgac atagtcttgg ttatttgttc
    37801 gtttctgacc aacatctgtt aataatgaaa tttccatgtg tcagttcctt cctaatccga
    37861 tatcttgcga aattgactga tgaagaatcc atcacttcca tacaattcag gtgtaatgag
    37921 gatacagccg tctttcatga tatccttaca ttcatgttct agttttacct gctcgaactc
    37981 gggatgactc tctaaaaagg ccttaacgac ttgaaaattc tcctctgaga cgatagtgca
    38041 ggtgctataa gttattatac cacctttgcc tagtatttga caaacactac ctaatatttc
    38101 taactgaatt tcctgcaagg acgcgaaatc tgccgtttct ttattgtatt tgatatctgg
    38161 ttttcggcgc aaaagaccga ttcctgaaca aggagcatcc accaaaatct tatcaaagga
    38221 atcctggtca aaaaactcat gcacctttct ggcatccaat ttttgagttt gaacccgatc
    38281 ttcaactccc agacgttggg cattttcttg aattaaatcc aacttgtggt cgtacaagtc
    38341 cagagcagta acctgacctg tcgtaagata agaggctata tgggctgttt tcccacctgg
    38401 cgccgcacag gcatcaagca ctcgctcatc accttgtaaa tcaagcgtcg gagcaaccag
    38461 ctgactggac tcgtcttgga tggtaatggc tccatccgca aacaaattat gccctgcaaa
    38521 atgcccctgc tccttaacca gaccagtggt tgctaaaagg gaatcattcg cctccaacaa
    38581 ggcttggatt tcctcttttc gacttaggtc tgttacacga atactggctt tgtttcgcac
    38641 taacaggctt tcaaagatgg cttttgctct ctcctctccg tattcttcct tgagtttggc
    38701 aactagccaa actgggagag aataggcaat ggagtcacgc ttgttttttc gcttgatgct
    38761 agcaatatct ggccagcctt cacgcaagat acggcgaagg acagcgttga ccaatttttc
    38821 actgcctttt ttacggagtt tggctaattc cactgcttca ttgaccacag catgatctgg
    38881 aattttgtcc aaatagcgga gttggtaggc actcatgaga agaaggacat agagccagct
    38941 gtctaactgg tctctgtctt cgataaagtg ggataggtac cattccagag tcagtttacg
    39001 ggctaccgtt ccatagacta gctcggtcac taagcccttg tctgctgcag agagctgact
    39061 ccccttgagg tgtttattta aggcaatatt tgaatatgct tgattcacaa aaacatcctc
    39121 tagcactgct agagctaaac ttctagccgt ttctacttta gtcaccaaat cgttctccta
    39181 cagtcaatgt acgtccaact ccattgagga aggaagcaat gtccatctta ggcttaccag
    39241 ctggctgcac ttgtttgagg gatagagccc cttcagccgt tgcgacaatc aattctttct
    39301 tgccgataga gagaatctca cctggatttc cctgaccttc tactggtagg gcttcataaa
    39361 tcttaaagcg gtcgccctta aggaaagtat gggcaacagg ccaggggttc attccacgaa
    39421 tttggttaaa gagttgacga ttggttttgt tccagtccag tttttcttcc tttggcttta
    39481 tatttggaga gaaggtaacc tgactcgtat cctgcggttc aggtttgata tcaccagcaa
    39541 tataggcagg cagagtgtcc aaaagcaaat cacaaccaac tagcgccaat ttttcaaaca
    39601 aggtgccaac attgtcctca tctgtgatcg gaatgctgcg acgagaaatc atatctcctg
    39661 catccatttc cttaaccatt tccatgatgg tcacaccagc ttcctcatcc ccttgaatca
    39721 aggcataatg gataggcgca ccaccacggt gtctaggaag gagggaggca tgaacgttga
    39781 cagcaaagtc catgctatca aggagtttgc ttgggagaaa ctgcccaaaa gcagcagtca
    39841 caattccatc tgctcctagc ttcataagat cttccatctc tggacttcca gataattttt
    39901 caggttggta gatagatagt cctgcttcct tggcagcctg cttgactggg gtttcttgga
    39961 taactttttt acgaccaaca gcacggtctg gctgggtcac aacggctaga atttcgtaac
    40021 ggtcatctgt caaaagtcct tttaagactg ttgctgaaaa gtcgggggtc cccataaaga
    40081 ttagttttgt catatcttct ccttcttata aaaattgctg cggctcatgg tcaatgctga
    40141 gacggagctc actattttcc cgttcttgag tcaaggccaa gacctggttg agggtcggcc
    40201 ccagctcatc ttctaaacgg tatttaatta aaatctggta atgatagagg ttgtgggtac
    40261 gggcaatcgg ttttggcgtt ggccccagaa tgggactggt ctctgacaag cctgaccgca
    40321 aaatgttcat gacttcatag gcacgtttga aaacctcttc ttctttcttg tgagaaaggg
    40381 taataccaat cgtgaaatag taaggtggat agccgagttg tcgtctgatt cccatttcat
    40441 aggcataaaa gccttcgtaa tcttgatcct tggcaaatcg aatagcatag tgctgcgaat
    40501 tgtaggactg tatcaagact tgacctgctt tttcagcccg acctgctcga cctgccacct
    40561 gagtcaagag ctggaaggtt ctctcagaag aacggaaatc aggcagattc aaggccgtat
    40621 ccgcatttag aactccgact agggtaacat tgggaaaatc caaacccttt gcaatcatct
    40681 gagtaccaag taaaatatcc gcttcccctc gcccaaactg gtcaagcaag gcttggtgac
    40741 tgcctttctt tcgagtcgta tccacatcca tcctcaaaat gcgagcttgg ggaaagagtt
    40801 ctgctagctc atcataagcc ttctgagttc ccgtcccata gtaacgaata ctgcggctct
    40861 tacagttagg acagacctga ggaatatcct tcgagaaacc acaataatgg cagttcatag
    40921 tcttggtatc catatgcaag gtcagagaaa tatcgcagtt gggacaagta tccaccgtcc
    40981 cacactcccg acacatgaca aagctagaat aaccacggcg attgagcatg agaaccacct
    41041 gctctttttt aaccagacgg tcttggatag cctctagcaa aggaggcgta aagtttgacg
    41101 tctcattttg tccgatatag tctcgaaagt caatcacttg aacctcaggg attgtagcca
    41161 aaggattggc acgttgggtt agacgtaagt gtcgatagac gcctttgcca gcacgtgccc
    41221 ggctctctaa gctcggcgtt gcagatccaa gtaccagagt tgcttgatta tactgagccc
    41281 gtaaaatagc tacctctctg gcatggtaac ggggattgct gtcctgctta taagccgctt
    41341 catgctcttc atcaataatc atgacaccca gatttttcag aggagcaaag atagcagatc
    41401 tggcaccaac aacaacttgg gcatcgccac gctccacctt acgccattca tcatactttt
    41461 cgccattgga taatcctgag tgaagaatgg ctaccttgtc cccaaaacgt gctataaaac
    41521 gctcggtcat ctgaggagtc aaggaaatct caggtaccag caaaatagct gtcttaccct
    41581 tatccagggc accttggata atctgcaagt aaacctcggt cttcccactt cctgtaatcc
    41641 cttgaagtag aaagggaggt tgagaactgc caatagaact cacaaccgca tcacgcgcct
    41701 gtctttgttc tggatttaac tccaaaggtc tacttgcttc aattccttca aaataagcag
    41761 ccgagcgttg aacttccttt tggactatgg taacagcacc ttgatccaca aagaagttga
    41821 cttgctctcg cgagtaggac tctaacaagc tagccaagga agcgctctct ggatgagaca
    41881 gcagataatc tctcagttcc aactttttct tggcacgtgt agaaatctca acaccttcta
    41941 attgggcatg gtcaacctca taccaagact gggtcttgac cttcttttga tcgactgcct
    42001 gatattccag accaagcagg ccttttctag tcaaacgcat catttcagct tgcttggcaa
    42061 ggtctagtga agaaaaggct agcgaatctt ctgaaccaaa caggcgtact cgttcttcct
    42121 gactcaagcc ttccagagga tagagaatct tgtcatagct agaattcaga aaccctggaa
    42181 gcatggcctt gaggatagag attttgtagg agaagacaga tttgcgtaac tcctcagcca
    42241 gccagagttg ttctggcgtg agaacaggag aaaaatccag cacctctgca atatctttta
    42301 aatcttgctc catctcttct ccatctgatt gggacttcaa accaagaaca atcccttgaa
    42361 tcaggcgatt ccccttacca aaaggcacat gaacccgcat cccaacttcc agcattccct
    42421 caaattcctc cggaatcctg taactatagg gctggtccgt ctgcatcaag ggcacatcta
    42481 cgataatctt agctagggcc atcttctcac ctcctccttg tcagtacatt cttgcaatag
    42541 aaaaaataag attgagtccc cccaacctta aattttttca ccatcttctt tttctttagc
    42601 aatttgctct ttgattttct tttcttcttc ttctttgcgg cgtttttctt cttcgatacg
    42661 gcgacgcact gcttcacgtt ttccttctgg atctgggtga attgtaacgt ttcctgattc
    42721 gatttcttct aaagcgcgaa gagttgattt ttcagacttg aaaccttgag ttgctggggc
    42781 acctgcttcc aattcgtggg cacgttttgc ttccaagatt acgagtgaat attttgaagg
    42841 aaccttgtcg agcaaggtat caatagaggg ttttaacatc atttgcttgt acctattttc
    42901 taaattttat cgggtagttg gagattttgg taacatctcc tgatagtgac caatgacacg
    42961 atccacacag aagtgttctg cttcaatcac acatttgaca cgttcagcag ctaggggcac
    43021 ctgatcgttg acaatcgcat aatcatactc acgcatgagg gcaatttctt ccttggcctt
    43081 ttcgattcgt tgggcaatca cttctgcact atctgttcca cgacctacca agcgatcttg
    43141 caattcatcc aaatctggtg gtgtcaggaa gataaagaca gcatctggaa cctttttctt
    43201 gacctgaaga gcaccctgaa cttcaatttc aaggaaaaca tcgattccct tgtccaaggt
    43261 ttcattgaca taggtcagag gagttccata gtagttgccg acatattctg cgtattccaa
    43321 catctgtcct tgacgaatca gctcttcaaa ttcttcacga gtacggaaga aatagtcaac
    43381 accgtccact tctccaggac gttgtgcgcg tgtcgtcatc gatacagaat attgaaattg
    43441 gttttcagaa ctctcaaaaa tctctcttct aaccgttcct tttccaaccc ctgaaggacc
    43501 agaaaaaacg attagtaagc ctcggtctgc cattgtgtct ccttttagtc aatctgtgaa
    43561 ataacatttc tctagaataa tggcaaaaag ccagattatc ctttacagtc tttctatcta
    43621 gtgtaacaaa aaagcagtaa tttttcaact gctctttctt atttatttag cataatctac
    43681 tgcacgaagc tcgcgaatca cggttacctt gatatttcct ggataatcga gattgttttc
    43741 aattttctta cgaactttgt gagccaagat tgtgactttg tcgtccttga tttttcctgg
    43801 attgaccatg atacgaattt cacgtcctgc ttgaagggca aagctagttt gcactccttc
    43861 aaagccgtta gcaatttctt ccaaatcatg gagacgcttg atgtagcttt caagagactc
    43921 actacgagca cctggacggg ctgcgctcaa ggcatctgct gcagcgacga taactgctat
    43981 cacgctctca gcttcaacat ctccgtggtg actagcaatc gtattcacca caactggggg
    44041 ttccttgtac ttacgggcca attccatacc gatttcaacg tggctacctt caacctcatg
    44101 gtcaatggct ttcccgatat cgtgaaggaa tccagcacga cgggcaagag ccgcattttc
    44161 accaagttcg ctcgccatga taccagccaa cttagcaacc tcaatcgaat ggcgcaaaac
    44221 attttgtcca tatgaagtac ggaactgcaa acgtcccata atcttcatca agtctggatg
    44281 aaggtttggc gcaccaattt cataggcagc agcctcaccg tattcacgaa tcttattgtc
    44341 aatctcttga cggtttttct caaccaactc ttcgatacga gctggatgta tacgaccatc
    44401 tttgagcaac atttccatag tcatacgggc aatctcacga cgaatcggat caaatcctga
    44461 caaggtcacc acttctggtg tatcgtcgat aatcacatcg acccctgtca aactttcaaa
    44521 ggtacgaatg ttacgacctt cacgaccaat aatgcgtccc ttcatagtat cgtctggcag
    44581 atgaactgtt gagtttgttg actccgctac atattcacca gcgatacgtt gcatagcttg
    44641 aaccaagatg tccttggcca ttttgtcaga acgttccttg acctcttgct cagcttcgcg
    44701 aatgcgactg gcaatctccc tggtcaagtt ttcctctgtc tgagccaaga taatatctcg
    44761 tgcttctgcc tgagacagag caccaatacg ctctagttct gcttcttttt gtctttcgac
    44821 ttcctctaat tgctcttcac gcgcatcaag gtttttcgct ctatcagaaa tactttgttc
    44881 tttttgttca agtgtttgtt ctttactcgt caaattgtcg tccttacggt caaggctagt
    44941 agctctctct gtcaaacgac tttcgatttg tttgagttct tgacgttctg atttgaattc
    45001 agcgtccact tcttcacggt attttctggc ttcttctttg gcctccaata gtgcttcttt
    45061 tttaagagac ttgctttcac gtttggcttc attaacaagt aaatccgctt cacgctcagc
    45121 ttgtccacgt aaattagttg cttcttgttc agcatttaaa agcatcaact ctgcagcttc
    45181 ctgagatgat ttcatcttag ctgagatgct gacatatcca atgactaaac caatgatgac
    45241 ggcaaaaaca gcaatcgcaa gcgacatgat ttccatgttt ttacctcatt ttattgttat
    45301 tccgaatgac atacattctt ttacattcta ccataaaaaa gtgattttca caaacctaaa
    45361 atagaatatg ttttggggaa tttggaacac atttaccaaa ataaacttgt tgtttagaaa
    45421 tagtagttta gtagagactt gagaaaaagc ctactttgca gtagacttcc taatgattat
    45481 gcaatacaag aagtttgttt ctaacaacag caagatttca ctcaggtatt ctctgtaaat
    45541 tagactagtg tcctgcgcga attttatcca ttcctcgcaa aaccttgtct gataactcct
    45601 tattttgggc gattctcagg gtttcctgaa tactgtccca ttcgctcttt gaaagaacta
    45661 caatgtcctc atctggattt ttattgacca ccgtcaaagg ctcaaattca tcatttacct
    45721 tcttcatgta atcctttaaa tgatttcgga atgttgagta aagaactcct tccataacca
    45781 tacctcgttt tagctctttt ccactattat acacgaaaag aaagaaattg tcaggaacct
    45841 gtacaagatt ttcttttcta tctatttata ctcaatgaaa atcaaagagc aaactaggaa
    45901 actagcctca ggctgtactt gagtacggca aagcgacgtt gacgcgattt gaatttgatt
    45961 ttcgaagagt attattcgta aaaaatctca aaaagcctac cttttagtag acttagtttg
    46021 tttctattct aatcggcact cttccaaaat tttgctctgc tatacttggc tttcctagtt
    46081 ggtaaatctg gtctgctttt tgggtcatag catcccaagg ttctttgcca attcggctga
    46141 ctagattgac ctgtcctttc agagacttga gatgttgcct gcctttttca gtaaatccaa
    46201 ggacatgaat ggcttctggc aagacatttt ccctagcctg caccaaaata taggtcaata
    46261 ggcgtctgac acgcgccttg gtgtaacgtt tggtagtcac taactcgacc aattcttcca
    46321 cagactgggc tgttttaata gcttctttaa tgcgcacagc catttcttga ttgacctgat
    46381 agatggtggt taggtcggga tttgacaaga tttgatagcg gagcaaggga aaatagtctt
    46441 cccagatcac cttactggcc tgctcaaata gggcaacaga aggcataaaa cgttctaaga
    46501 aatcttggtc cttctgatgt tgacggaggg ctgtcgccga ggcaaagtcc acatctttat
    46561 tcacagaatg gtaacctgcc ccctgacgct gaatcggatg cagcttgata tttcgtcctg
    46621 caaccgcctt tgcataggcc agagcaagaa catgattggg ggtattacct gaaaaatcaa
    46681 gaccagcaaa ttccttccac atagattggg ttttctgggg ataggaaagg gaatcaggca
    46741 gattttccac aaatttctcc atctcagcac ctttctctgt gtataagtca gcgattttct
    46801 gataatctcg aacttcctct gtcccaaaaa ctagactatc aatgcccaag cgatccaaga
    46861 tatccacagc tccttgacca aagaaatcag ctgcctgaac actgactaaa aagggcaatt
    46921 ccactaccaa gtctgcgcca ttttccagcg ccatctgggc ccttgtccac ttatccacaa
    46981 tagcaggctc tccacgctgc atgaaattcc ctgacatggc aacaattttc agtccctctg
    47041 cctgatccag caggtattta tggccattat gaaaaggatt gaactccgcg ataatacctg
    47101 tgatggtcat gctaatctcc tacttctgcg ccacaaaaaa ccaacgggtg ctagtttctg
    47161 ttggttcctt atcctcaaag tctgcataga gtttgaagga cttgaatcca gcctgttcca
    47221 gtaagatatc ataggtcaag atctcatagg tcctctcctc atgtacttca tcgtggcgac
    47281 taaaggaacc gtcagcctcc ttgataaaga aagtcagctc atgcacgatg gagtgaggag
    47341 cttcgtcctc atatgtatcc caaagcatgg caaaatcttc cgcattttca tggtaggaat
    47401 agccagggaa tacttcatct gtctggtagg tcgagtgcac gtcaaagatg aaaactccct
    47461 cttcattcag cgcattgtac acgtccttaa agacgtcccc tacttccacc tcatcctgca
    47521 tatagcagat agagtccgaa taacacgtga caaaatcgta tttccctgcc ttggacaaat
    47581 tcagcatatt accttctata aaagcaatct tttgcttggc tgaagttgct ctcttctccg
    47641 caatcttcaa catatccgca ctcaagtcaa gtccagtcac atcaaaacca gcctgagaga
    47701 agcgcactga ttgaattcct gtcccacaag ccagttccaa gagtttcttt ttctccttgg
    47761 tcttaggcaa atgacgcaga gaaaaatttg tccatttgtc gtataaacta tcgtccatga
    47821 ccgcatcata gaccgccgca aaggtttcat aagtcgccat aatcatgata ctaagagctc
    47881 catggtaaac accactagcc ctttaccttt ctatcaattt ttctaaaata agcaaagaaa
    47941 cccagttgac tacaactgag ttcatcttct aagcaagagc ttctgaaata tctactgaat
    48001 tcgcctcatg ccatagcttc tctagattat aatgggcacg catttcttct gaaaagatat
    48061 gcacgacaac agcaccgagg tccagtaaga cccagcctcc agctgcatcg ccttcgacat
    48121 ggctaccttt aaagcccgct tgagctactt tttcacggat attagctgcg atagcgtcca
    48181 actgacggct attcattgag ctagtgatga caaagtagtc cgtcacacta gtcaaatctt
    48241 gtacatcaag tgcgaggata tcctccgcac gtttctcatc agccgctttc acgactagtt
    48301 ctagtaattc tttttcgttc atttaatcct ctttttagaa aatatgtttg taatctagga
    48361 catctgcaaa gcgctcctcc caaatgtcct cataaaattc attaatcgtt tctgctggaa
    48421 tgtcatcccc atcaaaggtt gtgacagcac cttctggaac aataagctga tagccatatt
    48481 caaaggcaac cttgacagag gtatccacac aatattctgt ctgcatacca cataaaacta
    48541 atttttcaat cccctgctta tccaagtatt cttttaagcc agtttctttg aaaatactgt
    48601 tatacttctt ctgaaagacc ttttcagcag gttttcgatt taaaagcgca gataactgcc
    48661 aatcttctga tgtttgagct tcagagttct caatatgttg aacatagata atttcaatat
    48721 tcttgcttct agcctggttt tgtaaataag aaatttttcc caatagactt tttgtctgga
    48781 acccagtttc tactaaaaca ttctgaacat caatgattat aaaagccgtc ttcatttagt
    48841 tctctttcaa atagtgcaca aaggcgttat aggtttcaag ggtttgggga tagatgggga
    48901 atccctgatg agctagatac tccacggtac gagctgtttc gtaggccacc gccttattga
    48961 gcgatagact tgcaatctca cgcgccacat ctactccagg aaaggctcga ttgtgctcga
    49021 tatagtctgc gacgtagatg accttatcta ggtctgtcat ttgaccagca ccgactgtat
    49081 ggacttcaat ggctcgcagg atttctgaat catgcaaatc caaatcttcc tgaattttgt
    49141 aaattccgac cataccatgc cagacattat tgccccagtt tttgaggtca gggtctagct
    49201 ggtaacggtc aatcaaggct agaaattcct gatctgacaa ctttttagca tagtcatgaa
    49261 gaagacctgc tagacttgct ttctcaacat ctacaccaaa gcgctgagct aattccatag
    49321 cggcacgctc cacacctaga caatgggtta gacgtttctc aggtagaagc tctgccattt
    49381 tttccaacaa ggcctcacgg gagcagttga tatagtcttg ataggacatc agtagagccc
    49441 ctccttctcg atgtagtcta gcactggctg aggtaggaga aagttgggtt tccgaccttg
    49501 ggcaaggaag tcccgcacca tgctggacga gatatccatg agcggtacgt ccacccagat
    49561 aactggatag gaagtcccta ccttgtagcg tggacgctga acccccacaa actgaaccat
    49621 gtcaaccagt tcatcaattc ggtaccactt aggcagatag gcaaccatgt cggcaccgat
    49681 gataaagtaa taatccgtat ctggattctt ctctgtcaaa atcttcatgg tatcgtaggt
    49741 gtaggaaata cccttgcgct ccaactcaat ggtttcaatg actaggccgt caatcccctc
    49801 aattgccaac tcaagcatct tgagacgatg gtgttcaggg atggtttcct ttttatcaac
    49861 gtgaggaggt tggtattcag gcatgagaag aacttgatcc agtcccaact gttgccgtac
    49921 ttgatccgca acaatgagat gggcattgtg aacagggtta aaattccccc ctaaaatccc
    49981 aacttgtttg cgttttttct ccttgatttc tggctccaac tctaccttgg taaagggagt
    50041 caatagttcg attgtcatag gctagtcccc tttatttctc tataaaaaca gttatttgga
    50101 gtttcggtct tagatttctt tgactttctt agaaatcttg cgattttctt tcttgctaga
    50161 ttgtttaaac aaaatcaaga tgcgtcctat tttttggact gtatccacac cgatttcttc
    50221 ttccaaaatt tcagctactt cgtggatgtt ttcatctgtg ttttgtaaga gagtaacctt
    50281 gattaattca cgcgcatcaa gagcttgacg gacgctggtt ttgatttggt cgttgagtcc
    50341 atttttcccg atttggatga taggtttgag ggtgtgtgcc tggctgttga ggaaggcacg
    50401 ttgttttgat gttaatgaca taattttctt ccttgttttt ggatagttat tttaggtggt
    50461 gagggacggt cggaactaat tttccaaaga tttcatcttt gaaaaatgga tttcctgacc
    50521 tcacaattga gccttggtct caattgtgcc ccttgccaat ctacagattg gcaatcacac
    50581 cacggcaata actatcgcta tatgagctca ctttgttcgc tcagcgattt tgttttaaat
    50641 aattgctttt cgtgtgacga cggcgacgcc ttctggtgcc cagacggcga cttttgctat
    50701 gcctgttaca cgaatccagc ctaggcctga gatgactagg tctgtcttat ctttaatggt
    50761 aaagacatgc tggactagac ttgggaaatc ttctttttcc ttgctatttg gtggtgtcag
    50821 aagagttccc aggtgcttat cgtagaaagc actagctcct tcaagcttgc tacgatggag
    50881 tttgagttca ttatcaaaga aagcagtaaa tccttgcttt tctcctgcta taaagtcaaa
    50941 gcgtcccaaa ccacctaaaa atagggtttg ctcaggatta agctgatagg tcttaggctt
    51001 gatttccttt ttaggactga catacttgag gtttttggcc gtcaagtagt gagccatctg
    51061 gtggcggtgg ataattcccg gcgtatcgta aatataagat ccgtcgtcaa gcggaatctc
    51121 tattttgtcc aaggttgtcc ctgggaagcg tgaagtagtg atgacattct gatcacccgt
    51181 gatttcttgg ataatagcat tgattagagt tgattttcca acgttggtca caccgaccac
    51241 atagacatcg cggcccttac ggtagtgttc aatcttgtca atgacttcct taatggcatg
    51301 tttattttgt gctgaagtta ggaccacatc gactggacga agaccttctt catgggcacg
    51361 tttcatgagc cactggctaa tcttaccaga cttaactgac ttaggaagga tatctttttt
    51421 atttcctacc aagaggacat cattgcccga gacgaaacgt ggtaaacctg ggatgacaga
    51481 tccattaaaa tcaaagatat caataacatt gaccactaaa gcatcactgt ctcccacctc
    51541 gtgcaagagc ttgaggaaat catcgttcgt caactggaca tctgtgattt cattgtagtg
    51601 gcggagacgg aaacagcgtt ggcaatagac ttcgccagtc tccaaacctt tttcaagtgc
    51661 cgactggggg gtaaaaccaa gaccagcttt atctgtcgtc tgaatggttg ctccacaacc
    51721 aatacagaga atttcttcca tagttaaatt ccttttttat atgtaatcgg tccgtacttt
    51781 tcagtgattt ttctcataac acgacgctca cgagttcggt taatctgcgt tttgattgag
    51841 tcatgttgga ccaagggttt gactaaaatt gaccgaatcc ctgcacggtg ggctgctcgt
    51901 atatctgtca tgagctggtc accaaccatg accacttcct ttttgtcata gtggaattcc
    51961 ttcatagcac ggtcaatacc aaatgtgaag ggcttcaagg cccagtaaac gtaatcaatc
    52021 ccaaatttct caactgctcg ttgaacgcgt tttttggtgt tatttgacac tacgataatg
    52081 ccaatacccg cgtcccgaag gtcatgtagc cattgcttca tctctggcgt tccatcaggg
    52141 ttgttccaag caatgagggt attatccaaa tcgaccaaaa cagccttgat tccctgcgcc
    52201 tgcaggcttg ggactgtcag atcatagact gcttccacag caaaatctgg tatataattt
    52261 tcaatcgcca ttctggctcc ttttcttaac tttttttcgc aattttcctt agtaacaagg
    52321 ataaaacaat ccacaaacct gcactagcca aactgatata gagccaagca tggggctcat
    52381 ctgttaaagg taagggaaca ttcattccga aaaagcctgt cacgactgcc aaaacagcta
    52441 gcaagactga aatgatagtc aaggttgtca aattgtcatt cagattattg tttagaatat
    52501 tgttgtaaga ggctgaaagc tgctgtaaaa tctgagagat taggtctgtc atggatacca
    52561 gctgatgagc ctcaatcatg gcatcatcaa actgttctct ctcaatctca tcaaaactac
    52621 gatacaaggc atgaccttga atatgctcta acaaaatccg attttgtttg gcagctgccg
    52681 tcagataaac cataccagtc tccaaatcag acagggcaaa gaggtttttc ttggtagttc
    52741 gctggcgcaa gaggtcattg acctcatccc tactcttgtc catctgctca atgacaggat
    52801 agtaggcatt gctgataatt tccagactgg caaagagaaa cttataaatc gaaagcgtgt
    52861 catggctctc cagataacga gtcatctgtt caatgacata ggcgttcttg gtattactaa
    52921 tggtaatcag gcgacgatgc tcgacaataa aggtcatggg aaaagtctca tagtaggcct
    52981 tgtccttttt tacgtctagg acattataga taaaggtaac cgtcccactt tcacggtggt
    53041 agtccatgtg ggcgcgctcg tttctatcca gtgcgtattc aatggtttcc ttgtccaaac
    53101 cgtaaatttc agaaaggtct tctagtttat tcaactttcc taggtctagg tctatccagg
    53161 tacaaccatt gcccaactgc ttttctaaaa ccatcttttc tccttattaa actccctcta
    53221 ttgtaccaca aattacttaa aataacaggt ctagtctgtg cgtgagaaat tgctaacaac
    53281 tgtgatattt cggttaggga caaagtgaag gacttgctcc tcgctacgaa gctgtgtcgt
    53341 acgaattccc acactgacaa ccttacccga tacagtaatc ggtccatttg tcagaacgac
    53401 ctcatctccc acatccagtt gacgttcaaa gaggatgaaa aagccattga tgacatcaga
    53461 cagaaagcct tgggctccca taccaatcgc taccccagca ataccagctc cagccagcaa
    53521 actagaaact ggcaaaccta aaatcgacaa aatgcagtag agtaaaaaga aatatagcgt
    53581 ataattaaac acattttcta gtaaacgtga gatggttttt tggcgtccaa catcatgacg
    53641 agacattttt agagaaggtt tgacaattct ctgcaccatg gtatgaagca tttttttagc
    53701 aatataaaat acaatcaaaa gcagtaaaag agaaatgacc ttggttagaa tattctcgat
    53761 aatggttgtc acatctagct tttcaatata agcctgaata aatttttgca tataaaactc
    53821 ctttatttca ttataccata ttttcatcag tctcattctc cataaatatt caaaaaatag
    53881 acagaaaatt cttgattttg tctatcattt atactataat cataatcact acacaaaaag
    53941 gagattatta tgaaaagaat cattcatgct tggaataagg caagccttgt caagcgtatc
    54001 ttgattggta tgctttgtgg ggaatcctag gactgaccct tcctaatctc tcagggattg
    54061 ggctactcgg ggatttattc gttggaggtc taaaagctgt tgctcctatc ctagtctttg
    54121 ccctcgttgc caatgccctt tcccaacatc aaaagggaca agatagcaat atgaaaactg
    54181 ttgttttctt gtatatccta tgatagggac tttcgccgct gctcttgtag ctgtactagc
    54241 aagtttcatc gtccctattg aaattaccct aaatagtgcc aatactgaaa ttgcaccacc
    54301 agatggggtt gggcagatcc tcagcaacct cttgctcaaa ctggttgaca gcccagtcaa
    54361 cgcgccctgt ttactgctaa ctatattgga atcttatctt gggcagtcat ttttggaatc
    54421 gctatgagag aagccagtaa aaatagtaaa gaattgctaa aaactatcgc tgacgtgact
    54481 tctaaaattg tcgaatggat catcaatctg gctccatttg gaatccttgg tcttgttttt
    54541 aaaaccattt ctgacaaggg agtcggaagc cttgccaact acggtatttt attggttcca
    54601 ttagtaacga ctatgctttt tgttgcccct gtggtcaacc ctttgattgc cttcttcttt
    54661 atgagacgca atccttactc tctagtttgg aactgcctcc gtgtcagcgg tgtgacagcc
    54721 tttttcactc gtagttctgc gactaacatt cctgtcaaca tgaaactctg ccatgacctt
    54781 ggactcaacc cagataccta ttctgtttct atcccactcg gttctactat caatatggct
    54841 ggagtagcga ttaccattaa ccttttgacc cttgctgcag ttaacactct tggaattcct
    54901 gttgactttg ccacagcctt tgtcctcagt gtggtagcag ctatctcagc ctgtggtgct
    54961 tcaggtattg ccggaggttc cctccttctt atcccagttg cttgtagcct tttcggtatt
    55021 tctaacgata ttgccataca agttgttggg gttggttttg tgattggtgt catccaagac
    55081 tcatgtgaaa cagcccttaa ttcttctaca gatgtcctct ttaccgccgt tgccgaatac
    55141 gcagcaaccc gtaaaaaata actcatcaag gcaagcctgc tcatgtcttg tcttttacgc
    55201 ttttattcta acttattagg aaattcttat gtctattagc caacgtacga ccaagctcat
    55261 cttagctacc tgtcttgcct gcctgcttgc ttattttctc aatctttcgt cagcagtttc
    55321 ggctggaatt atcgctctct tgagcctatc tgatacgcgt agaagtactt taaaactggc
    55381 tcgcaatcgt cttttttcta tgcttctagc tctggctatc ggtgttctag cttttcactt
    55441 gagcggattt catatctgga gtctcggcct ctatctggcc ttctacgttc ctttagccta
    55501 caagatgggc tgggaaattg gcatcacacc aagcacggtt ttggttagcc atctcttggt
    55561 tcaagagtca acctctccag acctcctagt caacgaattc cttctctttg ctattggtac
    55621 aggatttgcc ttgcttgtta atctctatat gccttcacga gaagaggaaa tccagcacta
    55681 ccacacgctg gtggaagaaa agttaaaaga tatcctccag cgcttcaaat actatttatc
    55741 cagaggagac ggacgcaacc gagcacagct ggtagcagaa ttagacacgc ttttgaaaga
    55801 agccctcaga ctggtctatt tggatcactc tgaccacctc tttcaccaga ccgactacca
    55861 tatccactac tttgagatga gacagcgaca aagtcgtatc ctgagaaaca tggcccaaca
    55921 gattaacact tgtcaccttg ccgccagtga aagcctgatc ttagcgcaac tcttttcaaa
    55981 aattgcaggt caactgagcc agaccaatcc tgcttctgat ttgctagatg aaattgaacg
    56041 ttatctggaa gtcttccgga accgcagtct gcccaaaaca agagaagagt ttgaaacccg
    56101 cgccaccctt cttcaactcc tacgtgaagc caaaaccttc atccaagtaa aagttgattt
    56161 ttaccaaaaa tatagacagt aaaaaataaa accactaaaa aacagagctt gccagcattc
    56221 ttgaaaagta gtataattat tgcatgcgca atcatcttgt gacgcagaga ctgcccgtta
    56281 atggactttc ttctatttat gactctaaaa agaaaggaga cactatgacc tatttggaaa
    56341 aatggtttga cttcaatcgg cgtcagaaag aaattgaaag tctcttggaa gagaccattg
    56401 cccaacagag cgagcaaagt ctgaccttga aagagttcta cctgctctac tatctggact
    56461 tggctgaaga aaaatctcta cgccagattg acctgccaga taagcttcat ctgagcccga
    56521 gcgcagtttc taggatggtg gctcgcttgg aagctaaaaa ttgcggtcta ctcagtcgca
    56581 tgtgttgcca tcaagataga cgctctagtt ttatctgcct gacaaatgat gggcaaaaga
    56641 cactggcctc gctacaaaag actgtcgaag aaagcttgga agcaggtttg gatttcttga
    56701 tttaagatga ttttaaaaaa agttgcgtgc gcaatcattt ttcttgacat tctcttttat
    56761 aaggagtaaa ataaagttag cattaaacaa aggagtttta aacatgattg aaattaccta
    56821 tatagatgcc agcaagaacg aaagaactgt gactttcgag tcttatgaag actttgaacg
    56881 ttcgcaacaa gcttgcctta tcggcgtcgc agactactac cctgtccaaa aattaactta
    56941 caagggtcat aatttggact accatgggac ttatggagat atcttcttct atctcatgaa
    57001 acaagattta agccaatata actaaaaaaa ggagaaatac aatggcaaaa gcaattacag
    57061 atgcaacatt cgaacaagaa acaaaagacg gtttggtctt agtagacttc tgggcaactt
    57121 ggtgtggtcc atgtcgtatg caaggtccaa tcttggacaa attgtctgaa gaactttcag
    57181 aagatgtctt gaaaatcgtt aaaatggacg ttgatgaaaa tccaaacaca gctcgtgctt
    57241 ttggaatcat gtctattcca actcttctct tcaaaaaaga cggccaagtt gtcaaacaag
    57301 ttgcaggtgt tcacacagca gaacaaatca aggccatcat tgctgaattg agctaatcaa
    57361 acgagagacc aagtactttc tttggtctct tttttcttgc cctttgccat ttttcaaaaa
    57421 atatgctaga ctatagc
//
LOCUS       DBEJKC010000004        56720 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.004, whole genome shotgun sequence.
ACCESSION   DBEJKC010000004 DBEJKC010000000
VERSION     DBEJKC010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 56720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56720
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.004"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(1..297)
                     /locus_tag="ACL3G6_000252"
     CDS             complement(1..297)
                     /locus_tag="ACL3G6_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544851.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
     gene            complement(281..2440)
                     /gene="pfbA"
                     /locus_tag="ACL3G6_000253"
     CDS             complement(281..2440)
                     /gene="pfbA"
                     /locus_tag="ACL3G6_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HGR0544852.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3571..4797)
                     /locus_tag="ACL3G6_000254"
     CDS             complement(3571..4797)
                     /locus_tag="ACL3G6_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HGR0544853.1"
                     /translation="MPNYNIPFSPPDITEAEITEVVDTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSIYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAASRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4840..5532)
                     /locus_tag="ACL3G6_000255"
     CDS             complement(4840..5532)
                     /locus_tag="ACL3G6_000255"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGR0544854.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(5705..7456)
                     /locus_tag="ACL3G6_000256"
     CDS             complement(5705..7456)
                     /locus_tag="ACL3G6_000256"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0544855.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYGLLTFLALSFLLATMVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQETSDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGV
                     TYHKMYSLQAGAMADTL"
     gene            complement(7446..9191)
                     /locus_tag="ACL3G6_000257"
     CDS             complement(7446..9191)
                     /locus_tag="ACL3G6_000257"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0544856.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYTTSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLLAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGTI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGTHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9397..9693)
                     /locus_tag="ACL3G6_000258"
     CDS             complement(9397..9693)
                     /locus_tag="ACL3G6_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HGR0544857.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(9846..10303)
                     /locus_tag="ACL3G6_000259"
                     /pseudo
     CDS             complement(9846..10303)
                     /locus_tag="ACL3G6_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10437..11264
                     /locus_tag="ACL3G6_000260"
     CDS             10437..11264
                     /locus_tag="ACL3G6_000260"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HGR0544858.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTVTFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11276..11413
                     /locus_tag="ACL3G6_000261"
     CDS             11276..11413
                     /locus_tag="ACL3G6_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0544859.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLLKSV
                     N"
     gene            11524..11652
                     /locus_tag="ACL3G6_000262"
     CDS             11524..11652
                     /locus_tag="ACL3G6_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HGR0544860.1"
                     /translation="MKANYPIYRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12035..12130
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12530..13111
                     /locus_tag="ACL3G6_000263"
     CDS             12530..13111
                     /locus_tag="ACL3G6_000263"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HGR0544861.1"
                     /translation="MKLLEDRILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13111..14373
                     /locus_tag="ACL3G6_000264"
     CDS             13111..14373
                     /locus_tag="ACL3G6_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HGR0544862.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPLDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTRFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14424..14885)
                     /locus_tag="ACL3G6_000265"
     CDS             complement(14424..14885)
                     /locus_tag="ACL3G6_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DpnD/PcfM family protein"
                     /protein_id="HGR0544863.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(14882..15646)
                     /locus_tag="ACL3G6_000266"
     CDS             complement(14882..15646)
                     /locus_tag="ACL3G6_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HGR0544864.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(15827..16231)
                     /locus_tag="ACL3G6_000267"
     CDS             complement(15827..16231)
                     /locus_tag="ACL3G6_000267"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HGR0544865.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            complement(16301..17782)
                     /locus_tag="ACL3G6_000268"
     CDS             complement(16301..17782)
                     /locus_tag="ACL3G6_000268"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGR0544866.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLEMIEDSQTAREILGTELMDLVTPYPSQVNRDFWEAYVHSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            complement(17801..18979)
                     /locus_tag="ACL3G6_000269"
     CDS             complement(17801..18979)
                     /locus_tag="ACL3G6_000269"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HGR0544867.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLDRLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            19144..20151
                     /gene="galR"
                     /locus_tag="ACL3G6_000270"
     CDS             19144..20151
                     /gene="galR"
                     /locus_tag="ACL3G6_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HGR0544868.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(20197..21234)
                     /locus_tag="ACL3G6_000271"
     CDS             complement(20197..21234)
                     /locus_tag="ACL3G6_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HGR0544869.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(21235..21588)
                     /gene="nmlR"
                     /locus_tag="ACL3G6_000272"
     CDS             complement(21235..21588)
                     /gene="nmlR"
                     /locus_tag="ACL3G6_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stress response transcriptional regulator NmlR"
                     /protein_id="HGR0544870.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(21832..22722)
                     /gene="czcD"
                     /locus_tag="ACL3G6_000273"
     CDS             complement(21832..22722)
                     /gene="czcD"
                     /locus_tag="ACL3G6_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter
                     CzcD"
                     /protein_id="HGR0544871.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            22855..23391
                     /gene="sczA"
                     /locus_tag="ACL3G6_000274"
     CDS             22855..23391
                     /gene="sczA"
                     /locus_tag="ACL3G6_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator SczA"
                     /protein_id="HGR0544872.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(23557..24363)
                     /gene="pnuC"
                     /locus_tag="ACL3G6_000275"
     CDS             complement(23557..24363)
                     /gene="pnuC"
                     /locus_tag="ACL3G6_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HGR0544873.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(24708..26228)
                     /locus_tag="ACL3G6_000276"
     CDS             complement(24708..26228)
                     /locus_tag="ACL3G6_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HGR0544874.1"
                     /translation="MTNLIATFQDRFGDWLTALSQHLQLSLLTLLLAILLAIPLAVYL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLNGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITENQMSQLNYQVGVEGKSAEQVAKEFLQEQGLLKK"
     gene            complement(26221..26949)
                     /locus_tag="ACL3G6_000277"
     CDS             complement(26221..26949)
                     /locus_tag="ACL3G6_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0544875.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVEENIALIPEM
                     KGWTKEEIAQKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKILLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVS
                     NPETILKAPATDFVADLFGGSIHD"
     gene            complement(26964..27728)
                     /locus_tag="ACL3G6_000278"
     CDS             complement(26964..27728)
                     /locus_tag="ACL3G6_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HGR0544876.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(27732..28175)
                     /locus_tag="ACL3G6_000279"
     CDS             complement(27732..28175)
                     /locus_tag="ACL3G6_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGR0544877.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(28857..29153)
                     /locus_tag="ACL3G6_000280"
     CDS             complement(28857..29153)
                     /locus_tag="ACL3G6_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGR0544878.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNFARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(29175..30239)
                     /gene="pepA"
                     /locus_tag="ACL3G6_000281"
     CDS             complement(29175..30239)
                     /gene="pepA"
                     /locus_tag="ACL3G6_000281"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HGR0544879.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPYVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            30640..31341
                     /locus_tag="ACL3G6_000282"
     CDS             30640..31341
                     /locus_tag="ACL3G6_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HGR0544880.1"
                     /translation="MTKTILVTGGTSYISSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNAAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            31357..31467
                     /locus_tag="ACL3G6_000283"
     CDS             31357..31467
                     /locus_tag="ACL3G6_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HGR0544881.1"
                     /translation="MNYLFQEDSSSQIFNLGTKKGYTIKEIFKTAEELLN"
     gene            31764..32723
                     /locus_tag="ACL3G6_000284"
     CDS             31764..32723
                     /locus_tag="ACL3G6_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0544882.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            32713..33669
                     /locus_tag="ACL3G6_000285"
     CDS             32713..33669
                     /locus_tag="ACL3G6_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGR0544883.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSFFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            33666..34418
                     /locus_tag="ACL3G6_000286"
     CDS             33666..34418
                     /locus_tag="ACL3G6_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0544884.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            34514..35479
                     /locus_tag="ACL3G6_000287"
     CDS             34514..35479
                     /locus_tag="ACL3G6_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0544885.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(35704..35946)
                     /gene="yidD"
                     /locus_tag="ACL3G6_000288"
     CDS             complement(35704..35946)
                     /gene="yidD"
                     /locus_tag="ACL3G6_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HGR0544886.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDRFSLKRNQEGE"
     gene            complement(35946..36668)
                     /locus_tag="ACL3G6_000289"
     CDS             complement(35946..36668)
                     /locus_tag="ACL3G6_000289"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGR0544887.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVVNKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(36655..37224)
                     /gene="scpB"
                     /locus_tag="ACL3G6_000290"
     CDS             complement(36655..37224)
                     /gene="scpB"
                     /locus_tag="ACL3G6_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HGR0544888.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(37243..37971)
                     /locus_tag="ACL3G6_000291"
     CDS             complement(37243..37971)
                     /locus_tag="ACL3G6_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HGR0544889.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(37971..38705)
                     /gene="xerD"
                     /locus_tag="ACL3G6_000292"
     CDS             complement(37971..38705)
                     /gene="xerD"
                     /locus_tag="ACL3G6_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HGR0544890.1"
                     /translation="MRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETSLK
                     IYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEILYL
                     DSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVTIP
                     TALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFILRQ
                     IENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(38702..39163)
                     /gene="cbpB"
                     /locus_tag="ACL3G6_000293"
     CDS             complement(38702..39163)
                     /gene="cbpB"
                     /locus_tag="ACL3G6_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HGR0544891.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(39160..39681)
                     /locus_tag="ACL3G6_000294"
     CDS             complement(39160..39681)
                     /locus_tag="ACL3G6_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGR0544892.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(39657..40628)
                     /locus_tag="ACL3G6_000295"
     CDS             complement(39657..40628)
                     /locus_tag="ACL3G6_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HGR0544893.1"
                     /translation="MTNKIYEYKDDRDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(40625..41419)
                     /gene="racE"
                     /locus_tag="ACL3G6_000296"
     CDS             complement(40625..41419)
                     /gene="racE"
                     /locus_tag="ACL3G6_000296"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HGR0544894.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(41626..41874)
                     /locus_tag="ACL3G6_000297"
     CDS             complement(41626..41874)
                     /locus_tag="ACL3G6_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HGR0544895.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(42130..43755)
                     /gene="treC"
                     /locus_tag="ACL3G6_000298"
     CDS             complement(42130..43755)
                     /gene="treC"
                     /locus_tag="ACL3G6_000298"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HGR0544896.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMTDYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDTSENAGFSTGTPWLKVGKSYKDINVENEIKGLIFTFY
                     QDLIRLRKEMPIISEGNYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(43933..45900)
                     /gene="treP"
                     /locus_tag="ACL3G6_000299"
     CDS             complement(43933..45900)
                     /gene="treP"
                     /locus_tag="ACL3G6_000299"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HGR0544897.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATNPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            46085..46795
                     /gene="treR"
                     /locus_tag="ACL3G6_000300"
     CDS             46085..46795
                     /gene="treR"
                     /locus_tag="ACL3G6_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HGR0544898.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            complement(46828..47631)
                     /locus_tag="ACL3G6_000301"
     CDS             complement(46828..47631)
                     /locus_tag="ACL3G6_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0544899.1"
                     /translation="MTSLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMTDLMKPKLLLLDEHTAALDPKTSQMVMNLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(47644..48537)
                     /locus_tag="ACL3G6_000302"
     CDS             complement(47644..48537)
                     /locus_tag="ACL3G6_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0544900.1"
                     /translation="MNFVLSSLSEGLLWSIVAIGVYLTFRILDIADMTAEGAFPLGAA
                     VVVSQIQAGANPWLATLLALLAGMVAGLVSGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGTVFSLSLACFLLVCLVLTLLMKTEIGLVL
                     RSTGDNIPMSEANGVNVDTMKIVGYMISNGLIALCGSLFAQNDGFSDVTSGTGTIVVG
                     LSSVIIAEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYEIPNLDQNLVRLFNAILLAL
                     VLFAPELQKRLKIRGLKLRNE"
     gene            complement(48549..49486)
                     /locus_tag="ACL3G6_000303"
                     /pseudo
     CDS             complement(48549..49486)
                     /locus_tag="ACL3G6_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(49976..50902)
                     /locus_tag="ACL3G6_000304"
     CDS             complement(49976..50902)
                     /locus_tag="ACL3G6_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0544901.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(50913..51980)
                     /locus_tag="ACL3G6_000305"
     CDS             complement(50913..51980)
                     /locus_tag="ACL3G6_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0544902.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            complement(51989..52915)
                     /gene="oppC"
                     /locus_tag="ACL3G6_000306"
     CDS             complement(51989..52915)
                     /gene="oppC"
                     /locus_tag="ACL3G6_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HGR0544903.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            complement(52915..54411)
                     /locus_tag="ACL3G6_000307"
     CDS             complement(52915..54411)
                     /locus_tag="ACL3G6_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0544904.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSISLPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            complement(54478..56457)
                     /locus_tag="ACL3G6_000308"
     CDS             complement(54478..56457)
                     /locus_tag="ACL3G6_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0544905.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KAVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
BASE COUNT        16706 a        12812 c        10556 g        16646 t
ORIGIN      
        1 ttatttcatt ttattatact ctgttaattc atatgagttt aaaccgattt catctttaac
       61 ctcgagtaaa gcagtttcaa atatttgttt aagagttttt gattctttac aattaaccga
      121 caaactttct gataaaatat gtacaacttc tgagactgaa taacctatct cctctttaga
      181 attatataaa tctgtagctc caccaataat ccaaaaatac tgattttgtg aacctacaat
      241 atcctcattt tctacggaac ttccttgtat cgaacaaatt ttatttatct ttaccataat
      301 acttcaaccc ttttagtgtc aaaagtaaac caattcctgt cactgttaag aatagttcca
      361 taatcttgtt cgaaccagtc tttggtaatt tttgttttac atctactatt tctttagatt
      421 tattaatatg attttcagtt tctctgccat ctccaactat tttatagttt acttcttctg
      481 tcttattatc ttgtttattg tcgatcttgt cattcatttg tctattatct ttacttgagt
      541 taaactctcc gttcttctgg ttactatcaa ttacattatt tgaattagat tgtttttcct
      601 ctttgttttt ttctttttcg tttttatcac ttaaattatt tgttacaatt ttgtaaagcc
      661 cattctccgt tacaatattg aaattaccat cgctatcacg tataacaggt tctttcccat
      721 ttgcattaga tttgatgaat gatatatact taccggataa attataaaat tggttattta
      781 aaacggttat tttacccttt gaatcctcaa taacaattcc ttctttaccc ccgaatatac
      841 tattctctga gactactaaa ttatcactaa ctcgtaataa ttcaatattt ggttgttctg
      901 tttccttaga attattatta attacatttt ttgttacagt aatatctgat acttttccta
      961 aatattctgc actatctttt gcaactcgta tcgcttttgt tttaggatcg gcaatattaa
     1021 atatattttc ggcgataacc acctgtttat ttaaatctaa taggtcttta gtgtttttat
     1081 agctataagc atttactaaa gctgctccgc tttctcgata atgtacactc tctcctttaa
     1141 ctttcttatc aaagcgattt cctttgatta atacatcagt gaatcctgta aaacgtacac
     1201 ctgcatacat catgttatca aaatgattat ttaaaatttt aatattagag gggttctgtg
     1261 tcgacaatgt ttgatagtgt gtgccaattg ctgttactaa ttccccagat ttatcacttt
     1321 tgccaaaata ggaattttga atagtcacat tttcagattt tttcccatca tcattcaagg
     1381 cataaggaaa accttttcta gttaatggtt caatctgaat gctctcctta cttatgattt
     1441 gcccatcctt catcgttttg ggtaaggctt gcccaagaaa acgagaatta tcaactaata
     1501 catttttcga acctgcaatt tgaatagcat gcccttgata actatccttg aatgttacat
     1561 tttttatagt tacgttattt gaattcccaa tagcaaatgc acctgaagaa tttataagtg
     1621 gtagattttt tgctttagtt ccttcttcat tcaaagcacc gttcatatca atcgtaccac
     1681 cagaataact aatatcttct gttgggcccc attctacttg cgcaccatca tccgtaaata
     1741 aacctgtcat aaaaacaatg gaagggtgat tcttaatatt tataccattt agaattgtag
     1801 ctttctcatt caattctaag tgtgtatgac tttttaaaaa aacaatttct tttactaaat
     1861 aagttccttc aggaaaatat acatttcctc cacctagccc ttgagctgca gcatctattg
     1921 catcttgaat tgcttgtcga tcatcatgaa tcccatcacc taccgcacca taatctttta
     1981 cacttaaagc agtatcttca aattcttttt tgataattct gtcacttata acatcttcct
     2041 tataactctt attttcatta gtagatgtta ctgtagattc aactgttctg ttgtctaatt
     2101 gtgaattgga acgaatagta ccattagagc tgatgctatt aacacttaac gaattatcta
     2161 aaccattagt ggttgaatta gaggcaatca tttcagcaga acgattctga ttaacagttg
     2221 gtgaattatc taaatcatta gtaattgcat tagaagactc ttttgtagcc atcggtgaag
     2281 aactagtaac aacttcatcc gataaaatac cttggcttcc caaaattgaa attgccaata
     2341 gtaccgagca agtccccacc tttaatttac gaatactgaa tacctcatta ggaacaaaat
     2401 atttcatcag aacctccaat ttttttacta tttttaacaa ttgattatta cttttcttaa
     2461 aatagataga atgacaccgc tgtcattatc tttatcatat attttccaaa ttgaattgtc
     2521 aaggaataac acaagaaaat attaaaattt atactcttcg gaaatctctt caaactaggt
     2581 cagtgccgcc ttgccctaag tctaggttac tgacttggtc agttctatag tagactgaaa
     2641 ctataatagt acacctctac ttctaaaaca ttgttagaaa tcgatttgac tatcccgatc
     2701 gatttgtcct attcttattt ccttttacta tatctacaac ctcaaagcag ggttttgagc
     2761 tatctatggc caacttccta gtttgctctt tagccttcca ttcaaaagtg atgctatctt
     2821 tcttagcttg aatataaaat atcccattta ctatatttaa atttattgat atgttgtaaa
     2881 ttataaatga aagaacaaat accttgtcat acaagcattc gccagggata tttaccttaa
     2941 tatcgctcat atggcggatt gaaactaaaa cactacaata tatttcttaa atagaccttc
     3001 tataaaagct agatttaacc tcgataaaaa tagatgcagt gcttctaaaa tactggaata
     3061 gggcatatag gtaatcgtag acaagtgttt tatagattgt ctcgcaggag atctaatgat
     3121 gtatagcaag catcactaaa catatgggat atttgcgtta ttataatatc aacatgctat
     3181 aaattctatc atgcaaaaga atgactagaa catgaaagac aggcacaaaa ctttgaacaa
     3241 tattctgaaa acaaaaaaaa gacgctagtt tccacaatct cactcatgga aactcacgtc
     3301 tttcaaaaaa tagggtgaat tgaaaactag aacaagacac tagattttct aaatgatgtc
     3361 tagtaaggat tctaaatgct ataccaaatt gctcacatct tatttcaaac cacgggactc
     3421 ccacaagaaa ggaaaatcct ataaaaattc tctctctgag gagaaagagg cctcaactac
     3481 aggtgtaaac tattatcaat tgaaaacaac agtttttaca ctcaattaga ctttttaggg
     3541 gcaggatcac tttcgcttga ctgtagtttg tcattttttt gataaagtta gcactttttc
     3601 agaaactgtt ttgaaagtct caatgatata gtctacttct tcatcgctta atttagtatg
     3661 aagagggagg gtaatttcat tctcaaagaa ggcataggcc ttaggatagt tcgtcatatc
     3721 aaatccaaga ttcttatagg ctgtcaagag aggaagcggt ttgtagtgaa cattacttgc
     3781 aattcctgct ttagccaatt cttggatgat gaggttgcgt tcttctaggc ttgctccttc
     3841 tacacgggtg atgtagaggt ggcgtgaaga ttcgacagtt tcagtcttgt gtgccaaagg
     3901 atggatgcga gaagctgcaa aaccactatc atagcggtcc acaatgtcct tacggcgttg
     3961 caacaaactt ggatagcggt ccaattgtac caaaccaagt gaagccatga tatcggtcat
     4021 gttgcactta taggctggtg taacgatatc gtattcccat gaccccagtt gcatcttggc
     4081 aagagcatcc ttagtttgcc cgtgaaggga aaggatttgg aattccttgt acatctcttc
     4141 gtcatcaatc actggattgg ctttccaagt cgcacttcca ccttctgccg ttgtaaagtt
     4201 cttaactgca tggaatgaga aggaagtaaa gtcagcgata gaaccagaag gttgtccttt
     4261 ataaatagat cccaaagcgt gggcactatc agagacaatg acaatacggt taaaggcctt
     4321 ttgccacttg cttgaagcgg taaagaagtc acgttttttc tccacgactt ggaacaaacg
     4381 gtcataatcg caaacaatcc ctgcgagctc tactggaata atcaccttag ttttctcagt
     4441 gatagcttgc tcaagcaggt catagtccat ctcaaacgta tctgcttgga tatccaccat
     4501 gacaggggtt gctcccacgt gcgtaatgac actacatgaa gccgtatagg tcatggctgg
     4561 aacgatgact tcatcaccag gtcccacttc caaaacgcgt aaaatcaact ccagagcggc
     4621 tgtcgcagag ttgagacaaa cagtcttagg tgtctgtgtg taaagagaca agcggcgctc
     4681 cagttctttt gttttaggac ctgttgtgat ccaaccagaa cgcagggtat ccactacttc
     4741 agtaatttct gcttctgtga tatcaggcgg tgaaaatgga atattgtaat ttggcattga
     4801 tttgctcctt ttatctgtac tcattttctt atgactactt tattttagta cctcaaacac
     4861 ggtttgaaac atgattttga tgtccccaaa gaaactaaac tctcggagat aggcgaggtt
     4921 atagcgcatc ttttcaggaa gaacatgctc cacataggcc tgatcaactg acagaccttt
     4981 ctccgtcatt tgactgataa ttgtgtcctc atccttgtag ttgatgctgg ctggagaggt
     5041 aatccctgct tgcaagagca aggttgccat catttcaggg ctatactgct ctgtataacg
     5101 tggcacttca ggtcgtgtac cgacaaagga catctcacct ttaaggacat tgaccaactg
     5161 aggcagttcg tccaaacgga cacgtcggat gaaatttcca accttggtaa tgcggctatc
     5221 gttagcagaa gtcaccagac ttcctttttt atccgcatcc gtcaccatgg tacgaaactt
     5281 ccaaatcttg aaccgacggt tgtactgggt cacacgctct tgcttgtaaa tcactggccc
     5341 tttgctatcc aacttgatcc aaatgctcaa gatgagaaag atgggagagg tcagaaccag
     5401 taagaccaag gccaaaaccc agtccaagca acgcttgaaa atcagcgaac ccttcctttt
     5461 agagacaagc tggtagtaag actcaacctc gcttgatttc atttccacag gcaagtcttc
     5521 ccatttcagc atgctgttct cctttgtttt tattatacta tttgtcaaca tttttcatta
     5581 taccacaaaa tggaaaaggc ggtgaaagaa atctgtaatt tgaaggattt ccttctagta
     5641 ctcaatgaaa atcaaagtac agctttgaga ttgcagataa agctgacatg gtttaaagag
     5701 attttcaaag agtatcggcc atggcccctg cctgcaaact atacatcttg tgataggtta
     5761 ctcccagagc caagagttcc tcatgggttc cactctcgat aatgcgtccc ttatccaaga
     5821 catagatgca gttggcatct tgaatagtag aaaggcggtg agcgatagca atagttgttc
     5881 ggccctgtct catcttcgcc agagaagctt gaaccaagct ttctgtttca gagtcaatat
     5941 tggctgtcgc ttcatccaaa atcaggattt taggctggct ggcgactgtt ctagcaaagg
     6001 caagaagctg gcgttgccca gtagagaagc tcgaaccacg ctcggaaaca ggggagtcgt
     6061 acccctgagg aagttcttga ataaaggaat ctgcatccac aaaggctgcc gcagcctgaa
     6121 cctgctcatc actggtttct tggtacatgg cgatattgga cttaatagtt ccatgataga
     6181 ggaagggttc ctgcaagacc aaaccgatgt tttttctcag ctcttcttga ctgaaatccc
     6241 tgatatccac atcatccaag agaactctcc ctgactggaa ttcataaaag cgcatgagga
     6301 cattgataat agacgatttc cctgaacctg tatgacctac aaaggcaatg gtttcaccct
     6361 tattaacaga gaaagaaatg tcatccagaa tcggatgttt accgtcatat gagaaacaca
     6421 catgttcaaa acggatattg ccttcttgga ctttggcttg cccattttct tgaagaggtt
     6481 cataggtcct ctcgtctatc agggcaaaga cacgacctgc agaaaccata gccgtttgca
     6541 gagttgaaaa gttttgcgtc acctcaatca aggggtcaaa aaggcggttg atgtactgga
     6601 taaaggcata catggtcccg accgttatcc cgatagaaaa accacggtag ccaaagtagg
     6661 ccatcaagac tgcatagcct agaagtttca gcaaactcat ggcaggtctc aaaaagaggg
     6721 catccaaggc tacagaacgg ttggcgtaga ccaagtgttc ttggttgatt tcatcaaatt
     6781 ctgcctgcag gcgcttctct tgattaaagg cctgaataat cctgattccc tcgatattct
     6841 ctgccagctt actattgata tctgacaaga gacttctggt tttctcgatg attttcactg
     6901 acttttttcg atagagattg accaaaagga aaatcaaagg aagaaagagc aagactaaag
     6961 ccgtcaaacg aaaatccagc accaacatgg tataaagggt tgtcagaaag ataaaaactg
     7021 ctgagataaa gctggataaa atcccagaaa acatatcact aatcgtctcg gtatcgttgg
     7081 tcaaacgaga aacgatagaa cctgctggcg tcttgtcaaa gtaagacatg cccagtttct
     7141 ccatattggc aaaggcatcc cgacgaatat ccctaacaat actgtaagac acgcgcgcaa
     7201 agagaagatt gcctacatac tgaactacag tttgtaggat gtagagacca tagtagacca
     7261 gcaaaacggt aacggctagt tggttaagat tgctgagata ctggtcgata aagtgggaag
     7321 ccacgagggg tatgacactt ttaatgacca tcgtcgctag gagaaaactg agtgccaaaa
     7381 aggtcaggag tccataaggc ttgagataag acatcaagcg cttcaataca gcccattgtt
     7441 cttgtttatt ctgcatcttc ttctcctttc atttccaact gctgagactg gtaggtttgg
     7501 gcataccagc catccatcgc tagcaagtct tcgtgcgtgc ctcgttcgat aatttgacca
     7561 ttttgtagaa ctaaaataaa atctgcatgg acaacagcac tgaggcgatg ggcagtgata
     7621 atggttgtct tgtcctttcg cgtctccttg aggttgtcga taatcgcata ctctgtcttg
     7681 gcatctacgg cggataagga atcatccaaa atcaagatat cagggtctaa aatcatagcc
     7741 cgactcatag ccaaccgttg cttttgacca ccagaaagac tgactccttt ttcaccaatc
     7801 agcgtatcaa atccttgagg catgtctaca atatcttggt aaactcgggc tagcttagta
     7861 gcttcctcga ccgctgaaag gggcaagtta ggattgccaa agcggatatt gtctaggatt
     7921 gaagtcgcaa agagaaactg gtcctgagga acatagccca tgagactgcg aaggtctgtc
     7981 agacgatagt cccgaatatc gtgaccgttt agataaatag tacccttatc cacatcgtat
     8041 tcacgcaaga ggagcttgat taaggacgtt ttcccagagc ctgtctgccc aaccaagccc
     8101 agtgtttgcc cttttgccaa actaaagtga atatccgtca gtgtttcctc attttcaaaa
     8161 gcaaagctgt caatggcata ctccaaacgc ccattttcaa taccatccag aggaaactca
     8221 gggtcttgta caggagattc ctgagacaaa agattttcaa tccgctggta agaaaccttc
     8281 cctcgctgag tagtattaaa gaggaaaccg atggccagaa gaggccagac cagcatatcc
     8341 aaatagctga taaaggtgac tagattccca actgtaatct gcccttcctg aaccatcaag
     8401 gagccaacca aaagcgttaa aacataggac gaaccaacaa acaagagaac catagggtca
     8461 aagagactat catatttcat ggtttgcagg ttcttttgga aggttaattc attgactgcc
     8521 tgaaaagact tcaactcgtc tgcctgataa ccgaaagact tggtcacttt gatacctgat
     8581 acggactcct gtaccttgtt attgagttca gaaaaagcag cttgggattc gccaaaggcc
     8641 ttatgagtct ttctccctag gcgactagtc gtataggcca tgaaaggtag ggggagaatg
     8701 gcaacaagag tcatctgcca tgagatgcta aagagcatgg tcaacaaagt caccagagcc
     8761 gtgatagagg catccaccgc agacatgaca ccgccacctg ctaaacgagt caaggcattg
     8821 atatcattgg ttgcgtgtgc catcagatca cccgtccgat aggtttgata aaaggctgac
     8881 gacatttttg tgaaatgctt aaacaagcga gaccgcatga tctgtcccaa gcaataagag
     8941 gtcccaagga tatacatacg ccacacatag cgcaaatagt acataccaaa ggctgcaagt
     9001 agcaagtaaa ataggctaag aaggaggtcc tgctgagtta attgccccga tgtgatggca
     9061 tcaatgactc gccccataac cataggagga atgagattga ggacggaaac caagaccagg
     9121 gccacaatcc cgactagata acggcgtttt tctaacttga aaaaccacca gagtttttga
     9181 ataatggaca taaaatccct ttctgattgc aaatggaaac ctgaggccaa tactcaatga
     9241 aaatcaaaga gcaaactagg aaactagccg caggctgctc aaagcactgc tttgaggttg
     9301 tagatagaac tgacgaagtc agtaacctac atacggcaag gcgacgttga cgcggtttga
     9361 agaaattttc gaagagtaca agaccccagg tttttcttat tcataagtta cgactgtaac
     9421 agcacccttg tcatattcag caataaagat attggctaca ttgtcatgcc cttgtttact
     9481 gaggttatca agcaaccact cttcgctacg accaatcgat tccaagacat ctacttgaat
     9541 cacaccgtct gtcacaactg gatacttagg attttcatct cccatttgca caacgatgag
     9601 ttgcccattt tgctcttgca cagctcgttt gacttgcttc atctggaaaa tcccttggct
     9661 acgaagtttg agggctacat ccgatgcaga caaaccaact gaacgacagg cttatgggtc
     9721 aatattccca tttttgataa ggagagttgg cttaccatca atcaaacgtt tcacaaagtg
     9781 aacattgttg ttgagctatt tgaaagtcaa gatcagtttg attaaaattt cgatataatt
     9841 aagtgtcatt tgttcacatc caccagttca attgcgtctg tcttatacaa ttcgactttc
     9901 tctaacaggt acttgtctgg ctcacttccg tttagggcac gataatagcg atctcccacc
     9961 ttgataagtg cgccatctgt gtttgtggaa gtattaacat agacttctga cttgtctact
    10021 cccaaatctt tggaaacaac ctcgatgaaa tgaagtgaag tttgaaattt attgttagaa
    10081 acttgattgt tttgataagt cgtgatgctg accaaaagca gagctaaata aggccagagc
    10141 tgaaatcatg accaactcac gaaatttggt tcctttttta tcatggtatg ccttgaaagc
    10201 aaaaaaaaac tgtcacagct aatagaacaa tcccaaagcc aaccatgata ccattttgct
    10261 gaccgatttg gctgagtaca tagtcataag agtagaattt catgtatttt cactcccttt
    10321 cataaaatca ttcttaatta taaacgaaag agagtaattt ttcaaaccat acgttgggga
    10381 aatagatctt tttttggtat aataaaattt ataatctgaa tgaaaaaggt aactttatga
    10441 aacttatctc atggaatatt gattccctaa acgctgccct aactagtgac tcagctcgtg
    10501 ccaaattgtc ccaagaagtc ctacaaacct tggtcgctga aaatgctgat atcattgcta
    10561 tccaagaaac caagctttct gccaaaggac ctacaaagaa acacgtggaa attttagaag
    10621 aactcttccc aggctacgaa aacacgtggc gctcttccca agagcctgcc cgtaaaggct
    10681 atgctggaac catgttcctt tataagaaag aacttacacc cactgtcact ttcccagaaa
    10741 tcggtgcccc ttctaccatg gacttggaag gccgcatcat cactctagaa tttgatgcat
    10801 ttttcgtaac ccaagtttac actccaaacg ctggtgacgg tctcaaacgc ttggaagaac
    10861 gccaagtctg ggatgttaaa tatgctgagt atttggctga actagacaaa gaaaaaccag
    10921 tccttgcgac cggtgactac aacgtagccc acaatgaaat cgaccttgca aatcctgcta
    10981 gcaaccgccg ttcacctgga tttactgacg aagaacgtgc tggatttacc aaccttttgg
    11041 caactggatt tacagacacc ttccgccatg ttcatggcga tgttcctgaa cgctacactt
    11101 ggtgggcaca acgcagcaaa acttctaaaa tcaacaatac aggctggaga atcgactact
    11161 ggctcacaag taaccgtatc gctgacaagg tcactaaatc tgatatgatt gactcaggtg
    11221 ctcgccaaga ccatacaccg attgtcttgg aaattgactt gtaaggattt tctatatgga
    11281 ctacaatgcg gtcattcccg agttgcttgt atcgaatatc gaacagtccc ggtccttcta
    11341 ctgtggttta ctgggtttta ggattgaata ccaacgtcca gaagaaaact ttctcttgaa
    11401 gagtgtcaac taatgttaga ggagggaaca aaggatcaac tagctgaact gacctacccc
    11461 tttggtcgtg gagtcaatct ctcctttggc ataaaggatg ttccaaaact ctattaaaga
    11521 gtgatgaagg caaactatcc tatttatcgt cccttgacca aaagaaagtt tcgtgtcagt
    11581 gatccctata tctatcctca taaatttgca gttttggatc cagatggcta ttttttaaga
    11641 tttagcgagt agaataataa aaattgggaa aagtctttaa agttagaaaa aggcatattg
    11701 tcaggtgtct aaaaacttga tagtatgcct tttatgatgg aaaaatcttc taatactctt
    11761 cgaaaatctc ttcaagccac gtcaacgtcg ccttaccgta ggtatatgat actgactctg
    11821 tcaattctat ccacaacctc aaaacagtgt tttgaggttg tggatagctt cctagtttgc
    11881 tctttgattt tcatttagta taaatgttag cttacaatgg agtttttgtt caccccctct
    11941 tctgtttgtt cgttttttaa atcaaaacac taacaaaata gttgatttat aaagttattt
    12001 agtgtaaaat aaaaacattg gctcaagcct atttaaaatt gaatatcgtt ttacttgttt
    12061 atgtcgtgaa ttggcacgac gtttctacaa ggtgccggaa cacctaacaa taagtaagtc
    12121 agcagtgaga tatggtcgtt tttgccatgc ctatttgggg gacttactta gagattaagt
    12181 aggtcctttt tgaatatttt taatatttcc cttaattagt gcggacggga ggtgaaatta
    12241 tcctgtgaat aatttcagga attcagggaa tttcatccct aatttttgag cccctagctc
    12301 tttcatttct aggcttaggc taaaatagtt ccccgaacta ttttactctc aaaaatcccg
    12361 tcatagacaa taacaagatt attgtctatg ataccactac atcgggaaat atttgataag
    12421 actattacga gcgaagcgag tcttatcaaa tatatagtat tagcaaaagg gatcactata
    12481 gaaacatttc aacaacaagt aaattagctt ttagacttta ggaggtctta tgaaattatt
    12541 agaagatcgc atcctcaagg atgggcatat cttgggtgat aacatcctca aggtagattc
    12601 ctttttaacc caccaagttg actttagctt gatgcgagag attggtaagg tttttgcgga
    12661 aaaatttgct gctgccggca ttaccaaggt cgtaaccatt gaagcgtcgg gtattgcccc
    12721 agccgttttt acagctgaag ccttaaacgt tcccatgatt ttcgccaaaa aagctaagaa
    12781 catcaccatg aacgaaggca tcttaactgc tcaagtctac tcctttacca agcaggtgac
    12841 cagcactgtt tctatcgctg gaaaattcct ctcaccagag gacaaggttt tgattatcga
    12901 cgatttcctt gctaatggcc aagctgctaa aggcttgatt caaatcatcg aacaggccgg
    12961 tgccacagtc caagctatcg gtatcgtgat tgagaaatcc ttccaagatg gtcgtgattt
    13021 gcttgaaaaa gcaggctacc ctgtcctatc acttgctcgc ttggatcgtt ttgaaaatgg
    13081 tcaggtcgta tttaaggagg cagatctcta atgcaaactc aagaaaaaca ctcgcaagca
    13141 gccgttctgg gcttgcagca cttactagcc atgtactcag gatctatcct ggttcccatc
    13201 atgattgcga cagcccttgg ctattcagct gagcagttga cctacctgat ttctacagat
    13261 atcttcatgt gtggggtggc aaccttcctc caactccaac tcaacaaata ctttgggatt
    13321 ggactcccag tcgttcttgg agttgcattc cagtcggtcg ctcccttgat tatgattggg
    13381 caaagccatg gtagtggcgc tatgtttggt gcccttatcg catctgggat ttacgtggtt
    13441 cttgtttcag gcatcttctc aaaagtagcc aatctcttcc catctatcgt aacaggatct
    13501 gttattacca cgattggttt aaccttgatc cctgtcgcta ttggaaatat gggaaataac
    13561 gttccagagc caactggtca aagtctcttg cttgcagcta ttactgttct gattatcctc
    13621 ttgatcaaca tctttaccaa aggatttatc aagtctatct ctattttgat tggtctggtt
    13681 gttggaactg ccattgctgc tactatgggc ttggtggact tctctcctgt tgcggtagct
    13741 ccacttgtcc atgtcccaac tccactctac tttgggatgc caacctttga aatctcatct
    13801 attgtcatga tgtgtattat cgcaacggtg tctatggttg agtcaactgg tgtttatcta
    13861 gccttgtctg atatcacaaa agatccactc gacagcacgc gccttcgcaa cggttaccgc
    13921 gcagaaggtt tggccgtact tctcggagga atctttaaca ccttccctta caccagattt
    13981 tcacaaaacg ttggtttggt taaattgtca ggcatcaaaa aacgcctgcc aatctactac
    14041 gcagctggtt tcctggttct ccttggactg cttcctaagt ttggtgccct tgcccaaatc
    14101 attccaagct ccgtcctcgg cggtgccatg ctggtgatgt ttggttttgt atctattcaa
    14161 gggatgcaaa tcctcgcccg agttgacttt gctaacaatg aacacaactt ccttatcgca
    14221 gctgtttcaa tcgctgcagg tgtcggtctc aacaacagta atctctttgt cagcatgccg
    14281 acagccttcc aaatgttctt ctcaaacgga atcgtcgtag ccagcctact cgccattgtc
    14341 ctcaatgccg tattaaatca taaaaagaaa taagaaaaag aggtgcgagc ctcttttttg
    14401 tgtgacaaaa taaaaacatc tacctattca tatatgctag tgtcatagtc ctgaaaatca
    14461 tctgcatcaa gaacaatttc acaactctta tacttttctc ttacaagtcg ttcggcttca
    14521 tctggatttt cagcctctat acttactaaa cgtgataaag tttctgtaat ttctactgta
    14581 tactttttca gttttagatt gctttccaat aattcaccta ttaacaataa tctatgatag
    14641 gagctatgta gccactctgg caatttatct cctacttccc acccatattt ttccttcatc
    14701 aaagctagtt gtttttcgtc accaaatttc atattttcag ataaccatct cacacaatcg
    14761 ggatctgata aggtacagac gattaaactt aggttatcgt aacggctttc agtttcataa
    14821 tcaggccaga tgacttttaa gaaatcatac acctcttctg atgcaacaag ttgtttcgtt
    14881 ttcataattt ccgatacttt cctctacctt taaattctat tatttctttg tctcttaata
    14941 tttgaagctg ttgcctaatc ttttctttga tatgattgtt cttaacaaag atatttttta
    15001 ggtcactttc aaaacgatac atatcttcaa gggtaaattc tgaaccctct atcttatcta
    15061 tacaatttag aatttctatt gtccaacctc ttgatgacag agagctcttc cttaaaaata
    15121 aaccttgctt aaattctttt gtaacttttt ctggatctct aacttgtcca tcttgcacaa
    15181 gaaatatcct tcctttagaa ggtacttgtg ataaatcaat gttacaacca atccaacctg
    15241 ctcgtctagc agttggtgca agtggttttc tttgaataat cgatttcggt gtaacaaatt
    15301 gcttcggaag gacaagaaag ttatttacct caaaattttt tgtgtaagtt aaaaaaaaga
    15361 aattaggatt attatctgcc tgcacacgct tcatcatcgt tgcataagca ccatcattga
    15421 ttgttgatga aaaatttcct tttttgctct ttagttcaaa ctcctcacta caatgattac
    15481 agtaaaaatc tgctacaggc cgattatttt caaaatgatt taagggattg ttcccacaat
    15541 tagggcaata agactgacga taaacccaat cctccgttaa gatacgtgcc ttttggctat
    15601 tacttttata ggtttctact aattctaaat taaagtgtaa ttccatttaa aaattcctca
    15661 ctaatatgag aactcactcg atataagcaa ttaaaatcta ctataactag tataccacat
    15721 atatgtacct attacatttg tatttcatca ctctctttta tatttccttc taacatatct
    15781 cataaattaa aaatgagtga gataaattta tcccactcac ctttctttat atacttaccc
    15841 gtctttcctc agacctttgg cctgtgacaa acatggtaaa ggttgcttta cagacatttc
    15901 tgccctcttg attggtgata tccacatcca tcacacaggt tgtacgacct tgatggacac
    15961 attctccttt aatggtcaat acatcgtcga gttttcctgc cttaaggtag ttgatagagg
    16021 attggagtgt caccccatca agtcccagcg agataaccac caaaccactg atttggtcac
    16081 atagcgtgaa tagatagcca ccatgggcat tgccatagta gttgagcgac gagttcacta
    16141 ctttggtcgt caccacaacg tgaccatctc tcattttttc aatttcgtaa ttttcaaagg
    16201 cagatatagc gtcaaaatga aagtctttca tcgtttcctc ctgatatttc aaacgacact
    16261 atgatactac tttttatagg actgtgcaag gagaaagctc ctagtctagt aaaattccga
    16321 catgttccac aaagcgcata aaggctgtct gcccttgttc tgtctgcttg tagactcctg
    16381 catcctcaag tacacgcgca aagatagcac ccacagagtc cttgacgatt gcaagggctt
    16441 tttctttatc cgttaggtct ggatgttggg atttgagttg gtctgcccac tcctgatgat
    16501 aatcggcaac tgtaacagct tctcctacaa gatagctcgc gacttgctcc acttcttctt
    16561 tcagacgtgg tggcaagatt gccaagccca tgacctcaat caagccgata ttttccttct
    16621 tgatatgttg gacatccttg tggggatgat agatgccatc aggatgctct gctgaagtct
    16681 gattgtctcg caagaccaag tccaactcaa actgtccatc acgcttacgc gctattggtg
    16741 tgatggtgtg atgcggtgtc ccgtctgtct ctgctaaaat ctgcacacta gaatctgaat
    16801 actgacgcca ttcctggaaa atcttatcag ctaagttaat caaatcctct ttggaatccg
    16861 aagtcaagcg taggacagac attggccact tgataattcc agccttgacc tgctcaaaac
    16921 cagcaaatcg gaaggtcttt tgcaagggag ccaattccat aggaaatacg tgacggcctc
    16981 cctgataatg atcgtgagtt agaatagagc cccccacaat cggcaggtcg gcattagatc
    17041 cagcaaaata tcctggaaac tgctctacga tagccaacag acgttcaaaa ctctgacgac
    17101 taatggccat gggacgatgc tggccatcta aaaagataca atgctcatta aagtaagcat
    17161 agggcgaata ctggaacccc cattcctgac caaccatttc aaaacggata atccggtggt
    17221 tgctgcgagc tgggtggttg acccgaccat ggtaaccctc attctctaaa caaagttgac
    17281 actgaggata attactagct tgcaccaact tggctaccgc aatctctttc ggatcctttt
    17341 caggcttaga gagattgatg gtaatttcaa gttctccata atcagatgga acacgataag
    17401 cgatattttt agcaatggcc ttgagtttga tgtaatcatt tttctgactg agttgataaa
    17461 aatcctctat cgcttgctca ggagagtgga cataggcttc ccagaagtca cgattgacct
    17521 gactcggata aggagtcacc aagtccatca gttcagtacc aaggatttca cgcgcagtct
    17581 gactatcctc aatcatctct aatcgaacgg cttcctcaac tagctggtcc ttgaggtcaa
    17641 tcaatttatc cagattggtc tcaacttcca aaacaccttc tcccactcgt gccaaaacac
    17701 ggttggtcag gtagattcga tccatttcct caaatgaact ttcagaaatg acatgtgtta
    17761 caaatttatc tactaagatc actatagagc ctccttttga ctagtcaagg acgcgagtgc
    17821 cacctgcaac ttcagcgata tagaagcttg gagcgtatcc aactacttcc tcgtagtgtt
    17881 tgcctacagc ttccttaaag gcctcaacag tatctttttg aaccaaggca atggcacagc
    17941 caccaaaacc agcccctgtc atacgagcac cgagaactcc ttcttgtgcc caagctgtgt
    18001 gaacaagagt atccaattcc aaaccagtta cttcataatc atgctccaga gaaacgtgtg
    18061 acgcattcat caaacgacca aatgtttcca aatcacctgc ttgaagggct gcttgagctt
    18121 taagggtacg ttggttttca agcacagcat ggcgagcacg tttcaaacga ttttcatctt
    18181 taatcaaata gctatattgg tcaacggccc actcgtccaa ttcacccagg gtctgaatat
    18241 ccaaggcaac ttgcaattct tccactgctt tttcacactc agcacgacgt tcattgtatt
    18301 tagagtccgc caattcacgg cgtttgttgg tgttcatgat aacaacgaca ttgtccttca
    18361 aatcaagtgg caccaagtcg tattctaaag tattggtatc taagtaaata gcacgttggt
    18421 cagcccccat accaatagca aactggtcca tgataccaga gttgactccg ataaagttgt
    18481 tttctgtttg ttttccgatt ttaaccaaat ccaaacggtc tagttttaaa tcaaagagat
    18541 gctctgccac gactcctgtc aagagctcca aggatgctga agaagacaaa ccagcaccat
    18601 ttgggatatt cccataaaca taaaaatcaa aacctttgtc aatcacgtgc ccagcttctt
    18661 gcaagaaatg aagaacccct tttggataat tggtccagtt gtgctctttt tcaaacttga
    18721 ggtcagcgag aggcacttcg ataatgccct tgtcctcaaa gttagctgag tagaaacgca
    18781 agacttggtc gtcacgctta cgagctgcac cgtaagttcc caaggaaata gcagcaggaa
    18841 aaacgtgccc accgttgtag tctgtgtgtt caccaatcaa attaatacgg cctggtgaaa
    18901 agaaggtttg gtctgcttct tgaccaaaaa cagcaagaaa gtctttgcga aggacttcag
    18961 tagtaagatg ttgtgccata tgaattctcc tttgactgtc cgttaagcca tcttaacgtg
    19021 taatcgtttt ctttctattg tatccaagga atttcccaag gtcaatcctt tttactaaaa
    19081 ttttactaaa atatcagtaa aaagaagaaa aatatgatat actaacctaa tcaaggagga
    19141 tttatggcta ccttaaaaga cattgcacag ctagcctctg tctcaatcgc gaccgtatcc
    19201 cgtgtcctca accgcgacca gagcctatct gttacagaag aaaccagaca ccgtatttta
    19261 accgttgctg aagagctagg ctacaccaaa cacctcaaga caggcgagtc ccacaagccc
    19321 aagcaaaaga ttgccattat ccaatgggtc agcgaacaag gggagctaga cgacctctac
    19381 tactaccaga ttcgcctagg aatagaaaaa agagcccaag agttggacta cgatatcttg
    19441 cgctatttta atgaccatcc ttttacctta agcgaggaag tgattgggat tctctgcatc
    19501 ggaaaattta gccgagctca gatttctgcc tttgaagaat accaaaagcc tcttgtattt
    19561 ctagacagcg atacactttc cctgggacat acctgtatta tcacggattt ttacactgct
    19621 atgaaacagg ttgtcgatta tttcctcagt caagggatgg accgcatcgg gattctaaca
    19681 gggcttgagg aaacaacaga ccaagaagaa atcattcagg acaagcgtct agaaaacttc
    19741 aaaaactaca gtcaagcgag gggaatctat catgatgaac tggtctttca aggaagattt
    19801 actgcccagt ctggctatga cttaatgaag gaggccattc agagcttggg agaccaactt
    19861 ccgccagcat ttttcgcagc cagcgatagt ttagctatcg gtgctctccg tgccctccaa
    19921 gaagctggaa tcagcctgcc agatcgcgtc agcctcattt cattcaacga caccagtctg
    19981 accaaacagg tctatcctcc cctctctagt attacagttt atactgaaga aatggggcga
    20041 gcaggtatgg atattcttaa caaggaagtc ctccacggtc gcaaaattcc tagcctgacc
    20101 atgctgggaa ccagactgac attaagagaa agtaccctaa atcaagaata ggataacata
    20161 aaaaacgaat agagttctaa aactcctatt cgttttttat tcgattacaa tcatagactt
    20221 aatggtctta cgttcatcca tatctttgta ggcttggtcg atatcttcca gtttataact
    20281 tgaagtaaag acgcgacctg gattgatatc accatcaagg acggctttta gtaaaaattg
    20341 cttatcgtat gttgtagcag aagctgcccc acctgctaca gagatatttt gcataaatgt
    20401 cgaaccaaga gcacgattat tatagtgtgg gactcctaca aagcccatac gccctccatt
    20461 atgaagaaca cctagcgcct gttctatagc agcctccgta ccaacacatt caagtgctgc
    20521 gtctgctcct ccaccgagga tttcacgcac cttggtaatt ccttcttgac cacgttctgc
    20581 aacaacagct gtcgcacctg actccatagc catcttttga cggtcttcat gacggctcat
    20641 aaggataatt tgtgatgctc cacgcatctt agccgcgatg acagcacatt gaccaacagc
    20701 cccatcaccg ataacaacaa ccttgtcccc tttttgaaca tttgcaacac gcgccgcatg
    20761 atagcctgtc ggcatgacat ctgcaagagt caaaagggac ttgagcatcc cttctgtata
    20821 gtcagaaggt tgaccaggga ttttaaccag cgcccagttt gcatagtgga agcgaatata
    20881 ttctgcctga aaatcacccc ccaaattatt gccaatatga ttgtcgcaag aaccgtcaaa
    20941 tccagcaaga caggcatcac actcaccaca tccatgtgta aaagggacaa tcacaaaatc
    21001 acctggtttc accgtcgtaa tggcttcccc agcttcttca acaatcccaa tcgcttcgtg
    21061 tccactattt ttgtgtccag ctttcgtttc tggattacgg tacctccata aatctgaacc
    21121 acaaacgcac gcacgaacca cacgaataat cacatcatcc gcttctatta tttgcggacg
    21181 ttcaatgcta gcaagtccaa cctgacctgc ctttgtatat actgctgatt tcatttaaaa
    21241 ttttccttcc ttataaagtt taattttgag atttaaacga tttaaagctg tctgtagctg
    21301 agacaagcgc tcctctaatt tttgcttttc ctcttctaaa ataccaagcc tctcctctct
    21361 cgtttcatct cccttttggt agagcgacat atagtcaact aaactatcta cagagacacc
    21421 cgccgaacga aaacacttaa taaattccag cgcttcgata tcctgatctt gaaaatcacg
    21481 aatcccagta gcagtacgag taatcggtgg cacaagacca acccgttcat aataccgaat
    21541 cgtatccgct gaaattccca acaaatcact ggcagattta atattcacac gctaacctcc
    21601 tctcatttca ttcactgaat tcacgctatt ctaactcact tatcttatta tataactttg
    21661 agttgactcc aagtcaagca ttttgtatct aatcgaaaaa tttttatcat taacaatcat
    21721 atatctggag tttatacaat gctcttctct taccaatttt tgaaatattt aaataataaa
    21781 gaaattactc tattccaaat aagatagtac ccaagtattt ttcacttttt tctaatgttg
    21841 atgctcataa ctccgttcca agtcacacac ctttcgctta tgggtttggt gagtttctag
    21901 gtcagcatca atttcaatgg taatattttg aaaaccacaa tcttttagga aaattcgaat
    21961 agactcttta caagtttcca tatgttccat ttcttttaga caaacatgga caatggcatt
    22021 tttttccaaa gcatccatag tccagagatt aagctgatta aggctggcca cattgtccaa
    22081 tcgctccagg ccactcttta cttgcttgat atcaagacct tctggcacag catccaagaa
    22141 aatcttgagt gtagaccaaa aacgtggaag ggcttttgaa agaataaaga aagaaatgac
    22201 aagggacaaa agaggatcta ggatatacca gtccgtaaat cgaagaacaa tcgccatcag
    22261 gataacagct acccacccta gcgtatcttc cagaaaatgc agactcagaa tagactcatt
    22321 ctttgtcttt cccttaccaa ccaccagact cgctaacaga ttgatagtaa tcgcaataat
    22381 tcctaaccag agaatcccct catcattgac tggttgcgga tgcaaaatct tcgtgacatt
    22441 ttccaaaatg actagaacag agcccgttac gagaatcaca gctgttacca aggctcctag
    22501 caggctaaac cgcttatagc ccaaggtgta ctgattgtct tcttcacgat tggagattgt
    22561 ttctagaaaa gctgatattc caattgcaat cgcatctccc aagtcatgca cagagtcagc
    22621 aagaacagcg ctagaaccaa atactccacc tgcaataaac tcaacaatgg cataagtcaa
    22681 atttaagaaa aaagccaccc aaacagcata ttttgccttc atatttctca ttcctttgtt
    22741 ataatagatt tatgaacacc ttgttcatta tcattatcca ctaaaactca aagaaaggat
    22801 agaagcaaaa cgtcagcttt attcagttct gaacaatttg cctcaagtgt ccatatgact
    22861 aacattgacc gccgtatcag caaaaccaaa aaagccatct atcaagcttt tatacaactt
    22921 ttgaatgcta agggctacga ggccactact gttcaggata tcattgatct cgcagatgtg
    22981 ggacgatcca ccttttactg tcactatgag agtaaggagc ttcttctgga ccagctctgc
    23041 cgctacctct tccatcatct ttttgaaaga gagcaagcca tttcaaccga ggactacctc
    23101 gcccacctct ttctgcattt tcataaaaac caagaccata tcaccagtct gctattttcc
    23161 aaaaatgact acttcctccg tcaactccat aaagagctag aacaccatgt ctattccgtg
    23221 ctagctgata atttaaaaga agcccaccct aatctgccta cttcttacct ccaacacttg
    23281 gtcatgtcca actttatcga gacattgacc tggtggctca aaaaaggtca agatttcaca
    23341 gaccaggaag ttgtccaatt ttatctagac cttctcattc ctaaaaattg aatatagagt
    23401 aaagctcagt tgtcttattt ctagattact gagtttttta tcttttcaac aacaaaagag
    23461 gacccgccga tcctcttttt catactataa atccttgatt atcaactata tctgttttaa
    23521 tcgaaatctc aaaacagcac tttcaaacat cttttcctag ttaagtaaat cagtattctg
    23581 cttagctgcc ttgctccatt gataccaacc aactagactg ttaatgagat aaattagata
    23641 tttcccttga atttgcaggc tttctcccca ccagagatag attgaaaaga cattggtagc
    23701 cgcccagaat atccactgtt cacggtaaac agctgtcatg aggatttgcc ctaccccatt
    23761 ggttgcatct gtgattgaat cacgataggg acgattggca ccaatagact gataaatgaa
    23821 gccaaaggcc aaccaccaaa gcacactaat ggaaagatac tttgtccagc ccttgccgtc
    23881 cagtttacgc gcgacaaact cctgcttttc cttcttaaac tgtgcctgat aaatccaaac
    23941 tagaagtcca attggctgca tgactgtgaa gtaaagtgtc gtcagcacct caccataaaa
    24001 gcctttctgt agggccaaaa taaggtaaat aacagagtta atcaagccaa aaagataatt
    24061 acttgctcga ccttccgata caaagattac acagataatc cctgtcaagc tacaaatcat
    24121 cccaatccag tcaacaatac gatgttcgta aaccaactcc agccagagag gaaaacttcc
    24181 taaaaccagc aaataaatcc actgggcaaa actacgatgg gcaaagaggt catcccagat
    24241 agccttcata gttcctgaaa atcctaaatc agccatagcc gcaaccatac gacggtaacc
    24301 acctgacatt tcacctaggg ttgttttgat attttcaatt ttcttttgca aataagtatg
    24361 catcatttct ccttttgttt ttaaagagcc gtgtctggat agactttcgg acgcaacgct
    24421 ctattagata atgaactgcc tatacacaag atttctaacc ttagtcgaca tgagctgaaa
    24481 cctcttattt gttaagtagt tcacaaaata ttatacacct attttatgaa tagtcaactg
    24541 tctttacagt aaaattttag aaaatcatga aaattttctc tttctttcca ttttaagtga
    24601 cattcagtca ttctcacatc aaaaaagccc agacgaaatt gtctgagcat tcttttatct
    24661 agtcgtttaa ggaagttgag ttcagtatgt ttaaagtctc tgtcccatca tttcttcaac
    24721 aaaccttgtt cttggagaaa ctccttggct acttgctctg ctgacttgcc ttcaacaccg
    24781 acttggtagt tgagctggct catctggttt tctgtaatct taccagccaa tgtattaaga
    24841 actctttcca actctggatg tttcttgaga agagcttctt tcatgagtgg agccccttga
    24901 taaggtggga agagttgctt gtcatcttcc aagacctgta aatcataacg ctccaattcc
    24961 gcatcagtcg aataggcatc cgtgatttga atatcccctg actgaattgc ctgataacga
    25021 agagctggct gcatagtcgc cacattgaga ttgagaccat acattgattg caagccctta
    25081 tttccatctt cacggtcgtt aaactcaagc gtaaagcctg ccttcagctg cccttccact
    25141 tttttcaaat ccgaaatggt cttcaagcca tattcttgag caatcttttt cggaacagct
    25201 acagcatagg tattttgata agacataggt ttgagatagg ctagatgatc ctgcttggca
    25261 atgccatcac gcgccacttg ataaacctgc tctggctcat gactcacctt gggtgatggt
    25321 tgaagcaaac tttcagtcac cgtaccggta aattcaggat aaatgtcaat atcacctttt
    25381 ttcagagctt cataaaggaa acttgtcgtc ccaaaattcg gtttaacagt cgcagtcatg
    25441 ctggtatttt cttcaatcag caatttatac atattagcca aaatttctgg ttctgggcct
    25501 attttcccag caataatcaa gttttccttc tctttttgag ccaaaagggc tggactataa
    25561 gacagaccca gtaataaagc caccaaggca aaaccagaga aaatcgtccg caatttcgct
    25621 ttttccatta cttttagtag gaagttaaag gcaatagcta gcactgcaga agaaagtgcc
    25681 ccaatcaaaa tcagactggc attattacgg tcaattccca aaaggataaa ggaacctagt
    25741 ccccctgccc caatcaaggt cgccaaggta gccgtaccga taatcaagac cgctgccgtc
    25801 cgaattccag acatgataac aggcatggca agtggaattt caaacttctt gagacgctcc
    25861 catctggtca tcccaaaggc aatcccagcc tcttgcagac tcggatcaat tccattcagc
    25921 ccagtaatag tattttgtaa aatcggaaaa atcgcataaa tcactagagc tgtcaatgcc
    25981 ggtaaagtcc caattcccat caaagggata aagagcccca acaaggccag agacgggatg
    26041 gtctggaaaa tacctgcaat ctgcaagacc cagtcggcca gcttctcatg atagcgaaga
    26101 taaacagcca agggaatcgc aagcaaaata gctagtaaca aggtcaaaag tgacaactgc
    26161 aaatgttgag atagggctgt caaccaatca ccaaaacgat cctgaaaagt tgcaattaaa
    26221 ttagtcatga atactacctc caaacaagtc tgcaacaaag tctgttgcag gagcttttaa
    26281 aatagtctca ggattcgaca cctgacgaat ctctccatcc tgcaagacag caatacgatc
    26341 tgccaacttt aaggcttcat ccgtatcatg agtcacaaaa atcgttgtca tcccaaactc
    26401 tttatgtaat tcttttgtca gaacctgcaa ctgttttctc gaaatagcat ccaaggctga
    26461 aaagggttca tccatgagga gaatcttggg ctgaccaatc atagctcgga caataccgac
    26521 ccgttgctgt tctccaccag atagctcact tggaagtcga tgcccatact cagctactgg
    26581 taaaccaacc ttagccaaaa gctcttctgt tttttgagca atttcttcct tagtccaacc
    26641 cttcatttca ggaatgagag caatattttc ctcaactgtt agattgggaa agagagcaat
    26701 agcctgtaaa acatatccag tagaaagacg aagttcacgc tcatcatagt ctttgatgcg
    26761 cttcccatcc atataaatat ttccatcagt tggttccaaa agacggttaa tcatcttgag
    26821 catggtcgtc ttacctgacc cagaaggccc tactaaaacc ataaattccc catcctcaat
    26881 ctgtaagttg acatctctca agacatcctt ttctgtgtag cgcagtgcta catttttgta
    26941 ttcaatcatt ctttgtcctc aatttaaaac ttccctcgat tagtcaagtc ttctacctta
    27001 ggcatgactt ccttattatc ccaatgctcc acaattttcc cgttctctaa acggaagata
    27061 tcgtactggg cataagcaac gccatcaatc tgagtctgac catagctaac cacatagttt
    27121 ccttgtccta agagttggaa aacaaagtca aaagtgacac tatattcagc cacatagttt
    27181 ttataagcag cacttccttg tccaatctca tgattatgct gaatcaaatc gtctgccaca
    27241 taatcactcc actgctctag ctccccattt tggaaaattt ctgtcaagaa acggcgaacc
    27301 agctttttat tttctgcttt cttatccaaa tccttgattt caaaatctcc aaaaatttga
    27361 tctagttggt cattttcagg tgttcgatag tagtcaatga catcccaatg ctcaacaata
    27421 cgaccattct catccgcacg aaaagtatcc gtcgtcaccc attgagcttc tccaccattc
    27481 agatattgat gaacatgaac aaagaccaga ttgccatcct caatggtgcg gacaatctta
    27541 atctgacgct ctggatgacg ctcaaagaaa tctgcaaaga aggctgcaaa tccttctttc
    27601 ccgtcaggaa cacctgtcga atgttggata taggtatccc ctacagactg ggcttgagcc
    27661 tcagcaactc gtccgtcttg aatggcatgg atgtataggt tgtgagcatt tttcacttgt
    27721 tgtgacatat tctaaacctc atttcccttc tctttcaaat tcgccaaaat tctttcttga
    27781 aaaccttcaa attggtgaat ttcttcctct gaaaatcctt tgtaaaagat agtatccaat
    27841 ttctgactga cacgatgccc cacttctttc tgggacttgc ctaactccgt taaaactaaa
    27901 tacttcttac gcttgtcttt tccacacgga ctaacaatta caagcttttg ttcctctagc
    27961 ttttttatca tagtcgtcag cgtattattc gcaagcccag tcgcaagcgc gatatctgtc
    28021 gcagttgcgc agccagtttc actattccat aaaaccgcta aaatcttgcc ctgttcaccc
    28081 ctataaagag cctcaggatc ttgactcagt aacttttgaa aaatccgccc attcaacaaa
    28141 cgaatatgat gggctagcaa atgaccatct ttcataacac ctccaattta tttcgatatc
    28201 gaaatgaata aaacaattgt aacactcatc gttctaactg tcaactattt cgatttagaa
    28261 ataatttttg ataattatcc acaccaccat actccggctc aactaacttt taacgagagt
    28321 ttctaaactc cttcgtcctc cagtctacaa aagccttcca ttcgtactat cctatatttt
    28381 atgaggggac acatttttcc tatcagacca tttattttaa agatagaagt aaatcataat
    28441 tgcttccatc tgttctttta tagtatattg aagttagact agagcactgt atcttctaaa
    28501 acattgatag aaagcgattt gaatttccca atcaatttgt tcgtatttat agcatttcga
    28561 aactggaata ggacaccatg actgctaaaa gatttctata aattcatttg attttcctaa
    28621 tcaatttgtt catatcttat ttcattccgc tataatttca ccttacccta tctttttcgt
    28681 agcacccttc aaacagccta tcccctaccg tttgacgatt cctcacttcg ctccacttcc
    28741 attacagaag tttcttcact actatgggct cggctgactt ctcatgattc cttgttacta
    28801 ctatttgaac gctcacgaga tagatcttac aaaaaatgct ttgatccaca atggaatcaa
    28861 agcattttaa agagttcctc atacataagc gcagaagtcg cagttcctct gtacttggct
    28921 tcttctcttt tgataaagcg agcaaagttg agcaactcag gtgctggatg tttgggattt
    28981 aggagcaatt cacgattgac caggcctgag agacgaactg cctgcaattg ttcatttgta
    29041 gtaggcagtt ttttagcagt ctctaggaga gcagcaacta aatcttcact caaatcatgt
    29101 cgagcatgat tgtaaagatc ttttataagg ctttctaggt ttggttctgc catccctacc
    29161 acctccctta tggtttaata atgtttaatc aaatcaaccg ttgaacgatc caatttcttc
    29221 accaaggctt gtaagaaagc ttgcgcttct aggaagtcat ccattgcata gagggtttgg
    29281 tgagaatgga tataacgagc gcagacaccg atagttgttg atgggacacc accatttttc
    29341 agatgagctg cacctgcatc tgttccgcct ttaccacagt agtattggta cttgatacca
    29401 gcttcttcag ccgttgtcaa aagaaaatcc ttcatccctg ggagaagcaa gtgacctgga
    29461 tcatagaaac gaatcaaggt tccatctcca attttgcctt gaccaccgta gacatcacct
    29521 gctggtgagc aatcaactgc gaggaagact tctgggtcaa acttggttgt agaggtatga
    29581 gcgccacgca gaccaacttc ttcttggacg ttagaaccca gatagagttc attgccgagt
    29641 ttttgacctg ataaagcttc agctagctcg cttaccatga ggacaccgta gcggttatcc
    29701 caagcttttg agatgatatt tttttcattg gctgtcaaaa ttgcagaact atctggtacg
    29761 atggtatcac caggacggat gccaaaactt tctgcctcag ccttgtccgc aaaaccacca
    29821 tcaaaaacga tatcggcaat ggctggcatg gttggtcccc cctttccacg agtcaaatgc
    29881 ggaggaacag aacctgaaat cacaggaatt tcatgaccat cacgagtcaa gagtttgaaa
    29941 cgttggctgc taaccaccat ggggttccag ccaccgattt ctacgacacg gaaggtacca
    30001 tctggcttga tttcgctgac cataaaacca acttcgtcca tatgagaagc gaccaagacg
    30061 cgcggtgcat ccacagcttc tgaatgtttg ataccaaaaa taccacccaa gccatctgtc
    30121 accacttcat ccacatacgg tgtcaacttt tcacgaagat aagcacggac aggcgcttca
    30181 tgacctgaga ctgcagcaag ttctgttact tctttaattt ttgaaaataa tgttgtcatt
    30241 tcagttcctt ctttctttca tccattttac cactttttat aggagaagga tagtgggaag
    30301 gtggatttct aagttagtat cttagtcctg ctctatctta gaaaaggata gtattctctt
    30361 gcatgtagtg caaaatctag taaacattcc aaaattaact cgaatattta tttccaaaca
    30421 aaaaaacaat acaccatcaa agttgtttag atttttcatg aaatttacag aaaatagttg
    30481 acttcccttt cttctttctt taaatatata gttggttgag tttggaatag tacgctgtag
    30541 ctgctaaaac atttctagaa attaatttga ctttcctaat agagttgttc atatcttatt
    30601 tcaatttact atagtacaaa actagaaaag gaaaaaatca tgaccaaaac aattcttgtt
    30661 acaggtggga ctagctacat tagctcccat accgttaaag ctcttttaaa tgctggctat
    30721 caggtgcatg tcctcgataa tctctccaca ggaaatcgag cggctgtgga tagtcgtgct
    30781 agctttaaag aactggatgt ttatgatgct agcgccttaa aggcttactt agaagaaaat
    30841 cagattgatg ctgtcctcca ttgtgcaggt gaaattgttg tgagcgaaag tattgaaaat
    30901 ccaagtaaat acttcactgc caacgttgct ggtatgaacc aagttctcaa agtcttatct
    30961 gaagttggca ttcaaaaaat catgttctct tcgactgctt ctctctatgg aaataactgt
    31021 attgacaagc cggtgactga agataccctg ctcgaccctg tcaaccctta tgcagagaca
    31081 aaactgatgg gcgaacgaat gatttactgg atggccaatc gctacgactg gaaatatgtt
    31141 attttccgtt actttaatgc tgctggggct gaaatggatg cttcaaacgg tctgcgtgtg
    31201 aaaaatccaa ctcacatcat tccaaatatc aacaagaccg cattgggaca aaatgatagc
    31261 ttaaaaatat ttggagatga ctacgataca cgtgacggtt catgtattcg agattacatt
    31321 tatgtcttgg accttgcata ggctcatgtt aaaggaatga actacctatt tcaagaagac
    31381 agttcttctc aaatctttaa cttaggaact aaaaaaggct atactatcaa agaaatcttt
    31441 aaaactgctg aagaattact aaattaaaaa atcccacacg agattgttgc tcgacgtgct
    31501 agtgacccag ccagtgtcct agcagatgct tcaaaagcta aacaatatct tgattggacg
    31561 gctagctact ccctcgaaga tattatttta tcagattaag gtaaaaacat tttagaatag
    31621 gataacaaag gagaaagtct tgttgctctc tccttgttgt atttattaaa ttatcagaaa
    31681 ttttattgac agattagaaa aataatgtta catttatatc cgcagatatc tttcgatacc
    31741 aaatctacat gaaaggacgg ggtatgaaac tttctcatta tttaattggc ttacttctac
    31801 tcctagtctt tctctctatt agcattggga ccagtgattt ttcatgggga aagctatttg
    31861 atttcgacca gcagacctgg ctcctctttc aagagtcccg tctcccaaga actatcagta
    31921 ttctcctgac tgcctctagt atgagtatgg caggccttct catgcagact attacccaaa
    31981 atcagtttgc tgcaccgagt acagttggaa cgactgaagc cgccaaactg ggaatggtgc
    32041 tgagcctttt tgtctttcca tcggctagtc tgacccaaaa gatgctcttc gcttttgttt
    32101 catccatcgt attcaccctc ttcttcctag cctttatgac catttttact gtaaaggaaa
    32161 ggtggatgtt gcctctgatt gggatcatct atagcgggat tatcggctca gtcacagaag
    32221 ttatcgccta tcgtttcaat ctggttcaga gtatgactgc ctggacccag ggctccttct
    32281 ccatgattca gacccatcag tatgagtggc tcttcttagg cctcatcatc ctgataaccg
    32341 tttggaaatt atcccaaacc ttcaccatca tgaatctggg gaaagaaacc agcgagagtt
    32401 tggggatttc ctactcccta cttgaaaaac tggccctctt tctggtggcg ctaacgacaa
    32461 gcgtcaccat gattaccgtg ggtggcttac catttctcgg agttatcgtt cccaatcttg
    32521 ttcgcaagcg ctatggagat aatctaagtc aaaccaaact catggtcgca ctggttggtg
    32581 ccaatctagt tctggcttgc gatatcctat cccgagttct gattaggccc tatgagttgt
    32641 ctgtcagtct cttgctagga atcatcggta gtctcgtctt tatcctactt ctctggagag
    32701 ggggacgaaa agatgcagac taaaagcaaa cataccaagc tcttctggat tctcattatt
    32761 cttgccatcg gagcttgtct tctctacttt tggcccatca ctcacttgtc agcctttgct
    32821 tggaagttgc gttcccaaaa gatcatcgtt tatctcttgg tagccatcgc gactgggatt
    32881 tcgaccatta gttttcaaac cctgacggaa aatcgcttcc tgacgcctag tattttggga
    32941 attgaatcct tctacgtcct actacaaacc ctactactgg tttttgaaag caagtttctt
    33001 caacttggca aatcccctat cttagaattc ctagtcttac ttcttgtcca gtccttcttc
    33061 tttctcgcct tacaaggtta cttgaagaca ctgatgaagc aagacctggt cttcatcctg
    33121 ctgatctgtc tagcgctcag aagtctcttt cgaaatatca gcaccttcct tcaagtccta
    33181 atggatccaa acgaatacga taaactgcaa aatagtcttt ttgcctcctt tcaacatctt
    33241 aacacttcca tcctagccat cggttctctg atcatcctcg ctttgacaat ctttttcttt
    33301 cgaaaagcag tcgttctaga tgtcttgcac ctgcaaagag aaacggctca gatattggga
    33361 ctcgatgttg aaaaagaaca gaaagagctc ctctggggaa tcgtgctttt gacctcaacg
    33421 gccactgcct tggtaggacc tatggccttc ttcggcttta tgctggccaa cctcacctac
    33481 ctgattgtca aagactatca gcacaagtta ctctttatag tggccattct ggttggattt
    33541 attagcttaa ccttggggca agccttgatt gaacgagtct ttgcactgga aattcgtatc
    33601 agtatgatca ttgagagtgt gggtggcttc ttattcttta tcttactata taggaggtct
    33661 cgtcagtgaa actggaaaac attgacaaat ccattcaaaa acaggatatt ttgcaaggca
    33721 tttcgcttga agtcagtcct caaaaactga cagcctttat tggtccaaat ggtgctggaa
    33781 aatcgactct cctctccatc atgagcagac taaccaagaa agatcaggga gttctcagta
    33841 tcaaaggacg tgaaatcgag agctggaatt cgcaagaact ggctcaagaa ctaaccatcc
    33901 taaaacagaa aatcaattac caagccaaat tgactgttga agaactggtc agttttggac
    33961 gttttcccta cagccgaggt cgacttagat cagaagactg ggaaaaaatc cgagaaactc
    34021 tgaactattt ggaactgacc aacttaaaag accgctacat caatagcctg tcaggggggc
    34081 aactccagcg cgtctttatc gctatggtac tggcccagga tacggacttt atcttgctgg
    34141 acgaaccact caacaatctc gatatcaagc aaagcgtcag catgatgcag attcttcgac
    34201 gactggtgga ggaactcggc aagaccatta tcatcgtcct ccacgatatc aacatggcca
    34261 gtcagtatgc agatgaaatt gtcgccttca aggacggcca ggtctttagc aagggaagaa
    34321 ccgatcaaat catgcaggct gacctgctca gtcaacttta tgagattccc atcacgctag
    34381 ctgatatcaa taacaaaaag atctgtatct atagctagta acataaaagc tcaagttaga
    34441 gaaccttcag tctcttagtc aataagatta agagactccc taaatcgtta tcacatttta
    34501 aaaaggagaa attatgaaaa catcccttaa actttatttc actgccctag tggccagctt
    34561 cttgctccta cttggtgcat gtagtacaaa ctcaagcact agtcagacag agaccagtag
    34621 ctctgctcca acagaggtaa ccattaaaag ttcactggac gaggtcaaac tttccaaagt
    34681 tcctgaaaag attgtgacct ttgacctcgg cgctgcggat actattcgcg ctttaggatt
    34741 tgaaaaaaat atcgtcggaa tgcctacaaa aactgttccg acttatctaa aagacctagt
    34801 gggaactgtc aaaaatgttg gttctatgaa agaacctgat ttagaagcta tcgccgccct
    34861 tgagcctgat ttgattatcg cttcaccacg tacacaaaaa ttcgtagaca aattcaaaga
    34921 aatcgcccca accgttctct tccaagcaag caaggacgac tactggactt ctaccaaggc
    34981 taatatcgaa tccttagcaa gtgccttcgg cgaaactggt acacagaaag ccaaggaaga
    35041 attggccaag ctagacaaga gcatccaaga agtcgctact aaaaatgaaa gctctgacaa
    35101 aaaagccctt gcgatcctcc ttaatgaagg aaaaatggca gcctttggtg ccaaatctcg
    35161 tttctctttc ttgtaccaaa ccttgaaatt caaaccaact gatacaaaat ttgaagactc
    35221 acgccacgga caagaagtca gctttgaaag tgtcaaagaa atcaaccctg acatcctctt
    35281 tgtcatcaac cgtacccttg ccatcggtgg ggacaactct agcaacgacg gtgtcctaga
    35341 aaatgccctt atcgctgaaa cacctgctgc taaaaatggt aagattatcc aactaacacc
    35401 agacctctgg tatctaagcg gaggcggact tgaatcaaca aaactcatga ttgaagacat
    35461 acaaaaagct ttgaaataag ccacttcaaa ctcaatttaa tactcaatga aaatcaaaga
    35521 gcaaactaga aaactagccg caggttgctc aaaacactgt tttgaggttg cagatgaaag
    35581 ctgacgcggt ttgaagagat tttcgaagag tataaaattt tgacattcta aaacgcatcc
    35641 tatcaagttc actcaaacct gataggatgc gtttttatca ttttgaaatc tatttacccc
    35701 acctcattcc ccttcttgat ttcgtttaag ggaaaagcgg tctggaacgg ggtccttacc
    35761 tgttttcgac cagggatgac aacgtaaaat ccgagccaag cccatcaata cccccttaaa
    35821 accatgtttt tcaatagcct gaatcatgta gttggaacaa gtcagctcaa agcgacaaga
    35881 gggtggaaag actggtgaga taaaacgttg gtaaaagcgc acaggcgcta ttaaaattcg
    35941 tttcattatt tcttagttac agccatggtg tgtagttggc tgatttcttt tttattaaga
    36001 cgacgggatt ctcctggacg gagtcctgtc aagtctaggt gtccgaaacg agtccgagac
    36061 aacttatcta cttggagacc aacagcttca aacatctttt taacctgatg gttacgccct
    36121 tcatggatgg tcaactgcac cacagagcga tttttgactg ggtccacttt gagaatttca
    36181 taaacagctg gcttggtttt cttaccatca atctcaagac cacgggtcaa ggggcggaga
    36241 ttgtccttat tgaccacacc tttaacacgc gcgacataaa ccttgtcaat ctcattacga
    36301 gggtgaatca tctcgtctgt aaagtcccca tcattggtca aaatcaagac acctgatgta
    36361 tcccagtcca aacgacccac agggtaaata cgctctttga cattgggcaa gaggtcgaca
    36421 accgtcttgc gacccttatc atctgtcaca ctggaaatca caccgcgtgg tttgttaagc
    36481 agatagtaga ccttttcttc gttgtagata ggttgacctt caacttcgac cttgtcgcct
    36541 gacttgatag tggttgctag ttcacgcacc acttggccgt taaccgtcac caagccttgc
    36601 ttaatcagct cttctgcttt tctcctactg gccacacctg cgtgggcaat atacttattg
    36661 attctcatct tcttctatcc tttcaccaaa taattggctt tcttgggctt gaatctcaag
    36721 ctcatcaatc actggtaatt cttctaaatg gtttatcccc atgtaatcta ggaaataatc
    36781 cgtagtcaca tagaggttgg ggcgccccaa tacttccttt ttcccgtctt cctttatcag
    36841 gtcaaaagcc tgcaactttg ccaaggctcc actcgagtta actccacgga tggcatcaat
    36901 ttctatccgc gtaatcggct gtttgtaggc aataatggac aaggtctcaa gggcagcccg
    36961 agacaagctc tggttgatag gcgccttaga gtattccttc aaaatctctg caaattgagg
    37021 cttggtcacc aatctataag caccacttgt ctcaatcaaa gccaaactgg aatctgggtc
    37081 cttttcatac ttctgggcta attttcctaa actttgctgg atgcctgtcg gtggcagaga
    37141 gaggagttca gctaactggc ggacccgaat cccatcttca cccgctacaa acaagagcgc
    37201 ttctattttt gctaaagtac tcatctttcc tctctatcaa gtctagcttt gaggcacttg
    37261 actttcttcc ttcttttcca tgagatagat atctccgaaa ctctcctctt gcacgaggat
    37321 cagctcctgg gttttgatta actctagggt tgccaaaaag agggtgatga cctcttggac
    37381 attctgggct tccttgaaca aatcctgcaa gcgcaattga tctcgtccaa tcaaggactc
    37441 tttcacgata atcatcatgt cctcaatctt atactcatcc cgcaagatcg tcgtgtgatt
    37501 ttgtgcaaac tcctcttttt tcttggctag gatatttgaa aaagccaaaa agaggtcaat
    37561 ggtcgtcttg tcatgcacaa gctccgcatc ttcgtaaatc aactctgtcg gcgctttgga
    37621 ataatactgg gcccgttctt ggtgcttggc ttccaagtgc tcacccaaga gcttgaactt
    37681 gcgatattct tcgatttgag agaggaggtc ctgctccagg tcatccccca agtctgtcac
    37741 ttctgctacc ttcggaagga gtttacgact cttaatcagc atgagctgac tagccatgac
    37801 catgtactca cccgtcactt ccagacgcat ggcctgcagg gttgagacat aggctagata
    37861 ctgttcgatg acttccgtaa tgggcacatc gtagatatcc atctggtact tagaaaccag
    37921 atgcaagagc aagtccaggg gtccttcaaa atcttttaat ttaatatcca ttatctatat
    37981 ttttctaagg tcaggactgt ttttaatcct aatttttttg caatttcgta caaatcgacc
    38041 ttgttttcta tttgtcttag aataaactgt tcacgtaaga cttgagctga taaggatgga
    38101 aaacctttct ccttgacaaa agattctaac tgacgaaagg cccactgacg agaatagggt
    38161 ttctctcctc tttcaaaaag ataggtctgc cccatcaagg gttccaattc tgaaagcaag
    38221 gccgtgggaa tggtgacaat cctctgttgg gaagccttgc tgattcgcaa cacctgaaaa
    38281 tccagattga tgtccgcaac cttgatggct aaaatctcac tgggcaaaag ccccatttct
    38341 aggattaaga gcgctagcaa gcggccctct ggatggtcgc tttcctgcca aaaagagtct
    38401 aggtatagaa tctctggctt ttccgtcttc ttttcagctt gtttggctaa ttccaagcgg
    38461 taaaagctgt ccacctctcc tttttgatag agaaagtata gaaattggtt acaggccgaa
    38521 atctttcgct tctgggcgct gatttttaga ttggctagct gggcttggta aatcttgaga
    38581 ctggtctcag aaatccgctc acctaccatg tctaaaaatt gctccaaatc atacttatag
    38641 gactgcttgg aattgacaga caagccctgc ttttcctcta aaaaggctga aatcctgtct
    38701 ctcattggca tcgaatctca tattccttac taaagtcatg caagagggca ttaacggcct
    38761 tgaggatgga cttgcgcgta ataatccctt ggaaaatacc ctctgcatcc acaaccggta
    38821 agaaggactc atctactagc ttgtgcaaga cctccgtaat ggtgaaatca ggcgaaacaa
    38881 ccgctacgtc cgtttttgtc atatgaacga tatccgtatc cgccatgatt tcttggctca
    38941 agtcatgctc catctgatag gccataatat ctctgagtcc aatcgtccca acaaactgtt
    39001 tttcatctgt cacaacggga acacgggtat aggtcatctg actgagcaag agggtcgcat
    39061 gatccgcatt gtgggtatca atcaacacag ctagattttt agcaggggtc aaaaaagttt
    39121 cctcctgccc caacaagaaa gtctcaaact ccttggcaat catcggctaa actccttgga
    39181 caaacctgga tacacctcgt gatctcgtgt caaaaagtcc actttgaagt aactatcatc
    39241 aatctccaca cgagcataga gacattctct gatggtacct cgtggttggc tgatagaacc
    39301 tggatttaga aagaggatct tgccttccat ccaagcactt ggcacatgca agtgaccata
    39361 gaggcagata gcggcctctt cctcctgagc ccagtagtcc aacttttgaa agttgaaatt
    39421 gatgtcaaac aagtgaccat gagtttggat aatcttggtc gaaccaagct cagtcaccag
    39481 acgttctggg tagccggcgt agaagtccat gttcccttta acaacgcgga tgccctccca
    39541 aagtggagaa tccggacgta gttcagaatc gccgttatga aaaacggcat cgactttgcc
    39601 cacatagcga tcacggactt cttccacaat caagctatcg ccatgggaat cgctcattac
    39661 aatgatggtt tgctttgcca tgatggaaat acctccaaaa gtttcttaac ggctaaggca
    39721 cggtgagatt gactattttt ttcttccagg gttaattcag ctgatgactc acctgtctct
    39781 cctacaagga agaggggatc atagccaaag ccattttcac ccttaggttc aaagttaata
    39841 taacctgacc agtctgcttc aacaactaaa ctttccttat ttgggctggc tacgactagg
    39901 gttgtgtgga actgagccga gcggtccttg agttcaaaga ccatggccaa ttcgtgcaag
    39961 agtttggcat tattttcacg gtcagttgct cccacacctg cgaaacgagc tgaccagacg
    40021 cctggtaagc caccaaggac atcgactttg agaccagaat catctgccaa aaccatcttg
    40081 cccgttaatt gagaaatggt ttctgcctta aggcgggcat tttcttcaaa ggtcatacct
    40141 gtttctgcta cttcaggcag gtcagggtag tcattaagat tttccacatc gtagcctaac
    40201 ttatcaaaga tagctcggaa ttccttggtt ttaccttcgt tacgagtcgc aatcaacaag
    40261 gtttctctga ccttgcttgt ctcaaagaaa tcatgaacat tgaccccttc tttaggcaat
    40321 tctacataca agagttgccc attttcaacc aagagcaggg ccccatgacg ttgaataact
    40381 tccaagtttc gtcccatttc ttgattaagc atgtctacca caaaggagaa caaacggtag
    40441 gtagaaccat agcgtaaaac agtaactgaa agcgggaaac catactcttc atctccaaat
    40501 attttggaga attcaaacag aggaaaatct gtcttatagt cgctcaaact gttaacgcca
    40561 ccaaaaatac tataagaccc aacataccag tcccggtcat ccttatattc ataaatttta
    40621 tttgtcataa ttctacatgc tccacatgaa tctctttttc cagccattct tcaccaattt
    40681 gtgcaaaact ttggctactg gctgttgtgt aaaaacggtg atggagtggt ccagcatcgc
    40741 gaccacgatt gatttcaaaa taattgagta agactgagat atcccgtacg cactctgccc
    40801 cactatcgat gagctgaacc tttggcccca tcacattttg gataataggg cgaaggagtg
    40861 gataatgagt acagcccaaa atcaggctat ccacctttcc aaccaaggga cgcagggttt
    40921 catagaccac cttcttggta acactggttg acagggcacc tgactcaacc aagggagcaa
    40981 acttgggaca ggccaagctc tccacctgta agtcgggatc cagatcatgg attttctgac
    41041 ggtatatgtc tgattgtacc gtcatgggcg ttccaatcac tcctattttc ccaccttgac
    41101 tggacttgat ggctgccgaa gctcctggca aaattacacc caagacagga atatctagtt
    41161 gagccttgat ttcttcccag acgaccgcag tcgcagtgtt acaagcaatg acaatcattt
    41221 tgacatcctt ggtcaagaga aagttgacca gctgccaagt atattcacga atttgctcag
    41281 caggacgggg gccatagggc gcccgcgccg aatctccaat atagacgatt tcttcatggg
    41341 gaagctggcg catgagctcg cgcacaacgg tcaagccccc gacacccgaa tccaaaaaac
    41401 caattggtcg attatccata cagtcttctt tctagtcttt tttctgattg atcgttcatt
    41461 atgattcctt gtactgaacg aactgaccga cagcttgata gaatgtcaac tacctctctc
    41521 ttaatcataa tcaaatatca atagaatgca aggaaaaagt ctcatcccta aaccataacc
    41581 aacatagtga gaagtctgga actttcatcc cagacttttc cttatttatt ttttcttttt
    41641 attgttagca agggctgcct tttgttggcg gatgatttgg tggtaaactt gttgtacctt
    41701 agcttcgctt ggtttttgac catttgcact caaaagagta cgaactgctt cagcattcaa
    41761 acgtgggttg tcagcaaatt ctttttcgat ttgcttacga accaagtaca ttcctccaag
    41821 agctcctcct agaaaagcta gcacaatcaa tacaattgct aaaagtaaat ccatcatttt
    41881 tctcctgttt ctttttgagt ccctttcatt ataccacaaa ctagccaccc tgaccagttt
    41941 gttctacact ttcaaggatg gaatagacag caaaaagaac cctgcttttc tgaaaaagag
    42001 gtctccttgc taagtttata ctcaatgaaa atcaaagagc aaactaggaa gctagccaca
    42061 ggttgctcaa agcaccgctt tgaggttaca gataaaactg acacggtttg aagagatttt
    42121 cgaagagtat taatttacat aaatagccag tgtttgatag ggtttgagta gaattttctc
    42181 agacacttct gcatcttcat agtttgaaat caaaatctgt ccattttggt agactgctgg
    42241 caagtcgatt tccacttctt tggcataaaa gttattgagc actagtaact tttgatcctc
    42301 aaactggcgt tcaaaagcgt agacttgttt gctatcttca aaggctggtt tgtaatttcc
    42361 ttctgaaatg attggcattt ccttacgcag tcgaatcaag tcttgataga aggtgaaaat
    42421 cagacctttg atttcatttt ctacattgat atctttatag gatttaccaa ctttcaacca
    42481 tggagtgcct gttgaaaatc ctgcattttc agaagtatcc cactgcatgg gaatacgtga
    42541 attatcacgc gacttagctt gaataatctg gaaggcttct tgctgactct ttccttcttc
    42601 taagagcatc tgataggcat taagcgattc gacatccaca taatcagtca tagaatcata
    42661 gtctgggtca atcatcccga tttcctcacc catgtagata taaggtgtcc cacgtgacag
    42721 gtgaatgctg gctgctagca tggtggctcc ttccttgcgg aagttttgaa tatcgacaaa
    42781 acggttcaag gcacgtggtt gatcgtgatt gttccaaaag agggcactcc aaccgtcttt
    42841 atcactcatt tccttacccc aactatggta aagactcttc aactcttcaa aatcaaaggg
    42901 agccaaggtc cacttttgtc catccttata gtccaccttg aggtgatgaa aattaaaggt
    42961 catggataat tcctgacgat caggcgacga atagaggaca cagttttcca tggtggtaga
    43021 agacatttcc ccaactgtca taaagctatc gtcagatcca aaagtggctt ggttcatcat
    43081 acgcaaatag ttatgaacga tgggtttgtc tgtataagct ggcttccctt cattttcagg
    43141 acagtccact gaaacctcgt ccttaccgat caaattgatc acatcaaatc ggaaaccttt
    43201 gacacccttg tcgcgccaga aattaacaac cttgaaaagc tccttacgga cattggaatt
    43261 gcgccagtta aggtcagcct gggtctcatc aaataggtga agatagtatt tcccagtatc
    43321 cccgaaaggc gcccatgcag aaccaccaaa cttagactgc caatctgttg gttggtcttg
    43381 gatgaagaaa aagtcttgat aatacttatc accagctagg gctttctgaa accattcatg
    43441 ctctgtcgaa caatgattaa gtaccatgtc cagcataaag tcaatcttgt gctctttacc
    43501 gacacacacc atttcctcaa aatcagccat atcaccaaaa agaggatcca ctgccatata
    43561 atctgaaata tcgtaaccat tatcccgttg agggcttgga tagaatggat tgagccagac
    43621 catatccaca cctagtttgg ctaaataggg aattttttcg ataatcccac ggaaatcccc
    43681 aataccgttt tcagtggtgt ctttgtaaga ttttggatag atttgataga ctacttttcc
    43741 tttatcaagt gtcatctgtt tctccttttc tgataaaagg gaggaagcag tcttccgtcc
    43801 ctatttgtgc tatttcaatt atactcaatg aaaatcaaag aacaaactag gaagctagcc
    43861 acaggttgct caaaacacta ttttgaggtt gcagatagag ctgacgtggt ttgaagagat
    43921 tttcgaagag tattagattc gtgtagcgac catgagagat gctccagctt ggatcgttgt
    43981 cggataagtt ccaggaatag tcgctgtata agcatcttgg ttggtgatga taacaggagt
    44041 ttctgtcacc agacctgcag ccttaatgac atccatatca aaacgaatca gttgctgacc
    44101 aactgtaacg tgatctcctt ggactacaag actttcaaaa cctttgccat caagacctac
    44161 tgtatccata ccgatgtgga tgagcaattc aactccctcg tcagagacaa tgccgatggc
    44221 atgcttggta gggaaaagaa ccgtcactgt cccattaact ggagaggtca actcaccttg
    44281 gcttggttca atgaccagac cttgccccat gacacctgat gcaaaaatag gattcgtcgc
    44341 ttgactcaat tctttcactt ggccagttag tgggctgata atttctaccg aagtaagttc
    44401 tactggttca tggttcacaa attctgcttc ttcttgagca acgaattctg cctgcaagtt
    44461 cgtatcgccc tctgtttttg taaagagacc agccttgcgg aagaagaaag tcaagagcat
    44521 tggaacaaca atcgcaacta gcatagttcc tgcaaatggc agcatgtatt gaggttgaat
    44581 agagagaata cctggcaaac caccgatacc aatagaagcc gcagttacat taaaagtaac
    44641 ggataacatg cctgcaaggg ctgaaccagt catcccagca acaaatggat aaatatattt
    44701 tacgttaacc ccaaaaagag ctggttctgt aacaccgaga taggctgaaa tggttgcagg
    44761 aagtgaaacc tgagcctcac gctcatcatg gcgatgcatg aaataatagg caaacacggc
    44821 tgagccttga gcaatattag aaagagcaat cattggccat agggcagtgc caccagcatc
    44881 cgcaatcaat tgtgtatcaa tggcattggt catatggtgc agacctgtga tgacaaatgg
    44941 agcgtagagg gcaccaaaaa ttgcaccgaa gagccattta actggaccag ttaaacctgc
    45001 caagacaact gatgaaagtc cttgtccaat tgtccaaccg attggtccca aaacagtatg
    45061 agccaaaatc aaggctggaa tcaatgacaa gaaaggtaca aaaatcatag aaatgacttc
    45121 tgggatatgc ttgcgccaga agatttcaag ataagacaga ctcaaacctg caagcaaggc
    45181 tgggataact tgggcttggt aaccgatacg attaacagta aaatagccaa aattccaaac
    45241 ccagtttgcc gcgatatcag ctgctggcgt tgaagcaacc gcataggcat tgagcaactg
    45301 aggcgatacc aaacagattc cgagaacaat tcccaaaatt tggctggttc ccatcttacg
    45361 agaaacagac caagtaatcc ctactggtaa gaactggaag atagcttcac caggcaacca
    45421 gaggaagtga ttaacccctg cccaaaactg agaggattct gtgatggtct tgccatccaa
    45481 catcgaccaa tggacacctt ccaagacatt acggaaaccg aggatcaatc caccaacaat
    45541 caaggctgga ataatcggag taaagatttc cgccagagtg gtcataacac gttggaccac
    45601 gttttgatta ctcttagctg cagacttggc tgcttctttg gaaacaccct caatacctga
    45661 aacggctgta aaatcattat aaaagatggg cacgtcattt ccaatgatta cctgaaattg
    45721 acctgcattt gtaaaggttc ctttaacagc tggaattgac tcgatagctt taacattagc
    45781 cttcttatca tctcctaaaa caaaccgcat ccgtgtcgca cagtgagtta cggcagtcac
    45841 attttctttg cctccgattg cctgaagcag atctttggct tcttgttcaa attttcccat
    45901 ttgattctcc ttatacttgt caaagcaagt ttgatttgat aagtatattg taaacgatac
    45961 caaacttgtc tgcaacttgt ttggtataaa aagggtgttt ttttgtaaat tttctagcac
    46021 ttgtatggta aaatagatac aggtgttcat taaactagac taaaaaccta tttaagcagg
    46081 caaaatgaag aaataccaac aattatttaa gcaaatccaa gaaaccattc aaaacgagac
    46141 ttacgctgtc ggagatttcc ttcctagcga gcacgacctt atggagcaat atcaagtgag
    46201 tcgtgatacc gtccgaaagg ccctgtctct cctccaagag gaaggattga tcaaaaagat
    46261 aagagggcaa ggttctcaag tcgtcaaaga agaaaccgtc aatttccctg tatccaacct
    46321 aaccagctac caagaactag ttaaagaact tggactgcgc tctaaaacca acgtggtcag
    46381 tctggacaag attattattg ataaaaaatc ctcactgata accggtttcc cagagtttcg
    46441 gatggtttgg aaggtggtcc gccagcgtgt ggtggatgat ctggtatccg ttctggatac
    46501 ggactatctg gatatggaac taattccaaa tctcactcgc caaattgctg agcagtctat
    46561 ctattcttat atagaaaatg gcctcaaact ccttattgat tatgctcaga aggaaatcac
    46621 cattgaccac tcaagcgacc gagacaagat tctcatggac attggcaaag acccttatgt
    46681 cgtttcgatt aaatcaaaag tctatctcca agacggacgc caatttcagt ttaccgaaag
    46741 tcgccataag ttagagaaat ttagatttgt agattttgca aaacgcaaga aataaaagac
    46801 tgagacacca gatctcagcc tttttcttta tcccaaaact aattcatcac tgaccagact
    46861 ttggccacta tttttctgga agagatgcat aaggtcttca actgtcagat gctttttctc
    46921 ttctcccttg acatccacca ctatcttgcc ttgatagagc ataatgagac gattgccgta
    46981 ctcaatcgca tgattcatat catgggtaat catcaaagtc gtccactgat ggtgctccac
    47041 aatcttttgc gtcaagttca tcaccatttg actggttttc gggtcaagtg ccgcagtatg
    47101 ttcatccaaa agtaaaagtt ttggtttcat cagatctgtc atgactagag tcaaagcctg
    47161 tctttgtcct cctgagagat attgagtatc tacttttaag cggttttcaa gaccaatatt
    47221 caactccttc aaggcctctt ggaactggat tctatccttc tccttcacgc cccaaccaag
    47281 ccctctcttc tgcccgcgtc tcaaggcaat agccatattc tcctcaatcg tcaaacgaga
    47341 agctgttccc atcttaggat cttgaaaaac acgggcaata tccttggctc tctttctgac
    47401 actcagattt ttaatggatt tccctgccag tagaaggtcc ccttcgtcca ccgatagatt
    47461 gccagccaag atattcatca aagtggattt tcctgctcca tttccaccaa tcacagagat
    47521 aaaatctccc tcttcaacct ctaaatctaa tcctttgagg acatggttct cattgaccgt
    47581 ccctgcttca aatgtcttgt gaatattttc aagtgttaac aaacttgtca taactttctc
    47641 ctcctattca tttctcaatt tcagaccacg aatctttaat ctcttttgca attctggtgc
    47701 aaataaaacc aaagcgagca agattgcatt aaagagacgt accaagtttt gatctagatt
    47761 tggaatttca tagatattta aaataatcaa acggtaaaca atagcaccga ttccgatgga
    47821 taataagcgg cctccaatgg tcaagtcgtg tatcaagact tccgcaataa tcaccgagct
    47881 caaaccaaca acaatggttc ctgtcccaga agtcacatct gaaaatccat cattttgggc
    47941 aaacaaggaa ccacatagag caatcaaacc gtttgaaatc atgtaaccaa caatcttcat
    48001 ggtgtctaca ttgactccat tggcctcact catcgggata ttatccccag tcgaacgcaa
    48061 gaccaagcca atctctgttt tcatcaaaag ggtcaagacc aaacaaacaa gtaaaaaaca
    48121 ggccaaacta agtgagaaaa cagttccttc atttgtcaga cccaagctcg ccaactgttt
    48181 aaagacggtt gcagaatctc ccaaggaaag attgggtaca ctgcccatga ttttaatatt
    48241 gattgaatag agccctgtca aggtcacaat ccctgtcaag agagctggga ttttcatctt
    48301 ggtgtggagc attcctgata caagacctgc taccatacct gccagcaaag caagtaaagt
    48361 cgcaagccaa ggatttgccc ctgcctgtat ctgtgataca acgactgctg cccccagagg
    48421 aaaggctccc tcagcagtca tatccgcaat atccaaaata cggaaagtca agtagacccc
    48481 aatcgccaca atcgaccaca acaaaccttc tgataaacta gataacacaa aattcatctt
    48541 aatcctcctt attccttgcc ttctaactta ctaatatcaa ttcccaatgc atctgccatt
    48601 tcttgattgg tatgcaattc cagtttttca ggcaactcaa ctgctatatt ttctggtttc
    48661 tcacctttta aaacacgaat cagcatgcga gctgtctgac gtcccaattc ttcataattg
    48721 gttccgtagt tatacaagcc accaacagca atcatttctg ttgaaccacc gaatactgga
    48781 accttgtgtt taatagaaac ctgcttaact gtttccatgg ttaacgaaat gatattatca
    48841 gttgggacaa aaaccatatc cacctctgcc atcaaactct ctgctgccgc cttgacgtta
    48901 ttactgtcca agattgtttt ttcaacaacg gtaaagcctt tttctttcag aagtcgctta
    48961 gcttcatcct tttgaacaac cgaattgggc tcgctctgag tatagaggat tccaatcgtt
    49021 ttagcctttg gcaacacttt ctttatcaaa ttgatttggg ttgaaatggc atctgatgac
    49081 tgatcgcttg tcccagttac attgccccca ggatgttctc ttgactcaac caacttggca
    49141 ctgactgggt ctgttacagc tgaaaagata actggtgtcg tttgcgtcgt attggccaag
    49201 ctctgagcag aaggccttgc gatggctaga acgacatcgc tggattctgc tagttgctgg
    49261 gaaatcgttt ttagatttct ttgttctccc tgtgcatttt gcaaatcaat ctcaatattt
    49321 tccccctcaa catagccttg tttggccagc ttatccacaa atccttctct agtagcgtat
    49381 aaggactggt gggtaataaa ttgcgaaata ccgatacgaa agacatcttt ttcttatctg
    49441 ccttcaactg atgcaaactg atcagagaag tcaagaggag ccccactacc aagagggggc
    49501 tagtgatttt cgaacaactt tcataatgaa actccttctc agaaaagata aaacaaaaaa
    49561 ccgcctagat actatctaaa cggatacttg aaataaccta acaagttaca acttagctag
    49621 tccatttaga tattcatcta tatggaccac aatcaaaaat cttagccaca tagatacaaa
    49681 caaattgctt gaactgtttg catccatggt gacatgtcta caaacactat ctaaagtagc
    49741 taaagtaaaa gttttgattc atagttacgg cttgtctctt attcatttct ttttctgctt
    49801 tcttttttga tgcttcctgt cctaccacct ttttcatcac ctgtcaataa catttcataa
    49861 tttttaaaat ttttcaaaaa ttctttcagg aagctttcaa agtttttcaa atcagtccaa
    49921 caaaaaaagt tttataattt ccataaaaat tgacatggaa attataaaac cattactagt
    49981 ttagtccttt ttgataacgt gccaattcgg cttggttcgc ccaaacatag tgacctggac
    50041 ggatttctac catagatggc ttatcagtct catagtcgtg ttgacttggg tcgtaaacct
    50101 tcaagacctt cttacgttcc aagattggat ctgggattgg taccgctgaa agcaaggctt
    50161 gagtatatgg gtgaattgga ttgttaaaca attcttctgt ttctgcaacc tctacaataa
    50221 cacccttgta aataactgcg atacgatctg aaataaagcg aacaaccgac aagtcatggg
    50281 cgatgaagag ataggtcagg ccgagctctt tttggaattt tttgagcaag ttcaagactt
    50341 gggcacgtac agaaacgtcc aaggctgaaa ttggctcatc tgcaataaca aagtctggtt
    50401 gcatgaccaa ggcacgggca ataccgatac gttgacgttg accgcctgag aattcatgag
    50461 ggtaacgagt caagtgctca gcaagaagac ctacttcacg gataatattt tgaactttct
    50521 ctttacgttc ttcttcatcc ttaaataaac ggtgattgta aagaccttca gaaataatat
    50581 aatcaacagt cgcacgttca ttcaaacttg cggcagggtc ttggaaaatc atctggattc
    50641 gacgaatcaa ttccgcagct tgttcacgcg atttcttacc attaatcttt tgaccatcaa
    50701 aaatgatatc tccattactt gtatcattta gaccgatgat agcacgacca atagttgttt
    50761 tcccactacc ggactcacct acaagcgaga aagtttctcc cttgttgata aagaagttag
    50821 catttttaac cgcgacaaac ttcttacttc cttcaccgaa ggaaatttct aaatctttga
    50881 tttctactaa tttttcagac atttccttcc tcctagtcag ccagatgggc aaatcccatt
    50941 ttttcacgga tcttatcatg gagatttgca atcacagctg gtttttctac ttttggagca
    51001 tcctcatgaa gaagccaagt tttagcccaa tgtgtctctg atactgagaa ttgaggagct
    51061 ttttgttcga agtcaatctg cattgcgtag tcagaacgca aggcaaaagc atcccctttc
    51121 aggtcagtat aaagtgacgg aggtgttcct gggattgagt aaagatcccc tttatcatca
    51181 gcaagctgag gcaagctaga caagagactc catgtatatg gatggcgagg gtcatagaag
    51241 acttcctcaa ccgttccata ctcaacgatt tctcctgcat acataaccgc taccttatcc
    51301 gcaatacttg ccaccacacc aaggtcgtgg gtaataaaga ttgttgtgaa atgatactcg
    51361 ttttgtaaag attttagcaa atcaataatc tgagcttgaa tagttacatc caaggcagtt
    51421 gttggctcat cacagatcaa gacatcaggt cggcaggcaa gggcaatcgc aataacgata
    51481 cgttgacgca ttcctccaga atattggaat gggtattcat taaaacgtct atctgcgtct
    51541 ggaatgccaa ccttattcat gtagtcaatg gccaattctt tcgcttcttt agctgttttt
    51601 ccttggtgtt ttacaataac ttctgtaatc tgactaccaa ttgttttaat ggggtccaaa
    51661 ctagtcattg ggtcctggaa gatagtcgca atcttagcac cacgaatttg ttcccaatcc
    51721 ttgtgagaag ataaagctgt caagtcctga ccacggtagt caatactacc ttgggcaatg
    51781 cgaccatttt cttcgagcat acctgtgaag gtctttgtca aaacagattt acctgatcct
    51841 gactcaccta ccaaggctaa tacttctcct tcgactagtt caagggaaac gccgcgaatg
    51901 gctgtcaata ctttgtcacg aacgtcaaat tccacgacaa tatcgcgagc agtcaaaatt
    51961 acattttttt cttttgtcat ttctactcct atctatgtgt acgtggatca ctagcatccg
    52021 ctaagttttg accaactacg aaaagggaca aggataccaa gacaagggtt gtcaatggaa
    52081 tccagaacaa gtaagcattg gttgttacgt tttgtgaata atccgaaatc aaacgaccca
    52141 aacttggcac tgtaatcggt aatccaagac cgaagaaaga caagaaggct tcgtatgaga
    52201 taaagcttgg aagcatttga gtcatggttg tcacaataac agataccaat tgaggcatga
    52261 tatttttggc aacaatcttc aaggttggtg ttcccaaagt acgtgacgcc aagttgtatt
    52321 ccaagtcacg atagcgcaag atttgcacac ggatcatgaa ggcaatacca atccatgttg
    52381 ttacgctcat ggcaaaaatc agattccaga atccagctcc gattgagtaa gtcaagacaa
    52441 taacaatcaa aagaggtggg atgtttgaga tgacgttgta aacttccatc atgacacggt
    52501 caactgattt tgaaataccc caaataccac cgacaaaaac accgataacc aagttaatca
    52561 ctgtcgcaat cacagaaatg aggatggagt tacgagctcc gaaccagaca ccgtcaaaga
    52621 gcgatttacc gttactgtca gtaccgaacc aatgctccgc atttggcttg atataacgaa
    52681 cactaaagtc gtttaccttg ctgacatcat tgaaatcaaa cttagaaaac attgggtaga
    52741 tgaaacttat caaaatgatg gctaccaaga ttcccaacat gactacagtt gattttttct
    52801 tcataaattg tttaaacact gatttccagt aagaatatgc tggcgcatca atagtttcag
    52861 aggcaaaatc gtcacgtttt acaaactgaa atttttcttt atcgattgta gacattattt
    52921 gcctcctttc tcagtcaatt taatacgtgg gtcaataata gtcatccaaa tatctcccaa
    52981 aagacgtgag aagatagaaa tacatgtaaa gatgaagaca agaccaacga ccatagagtt
    53041 attagatgct tttacagagt caatcaacat tttacccata cctgggaagg cgaagactgt
    53101 ttcagtaagg gttgcaccac cgataacccc aataatggca ccaggaattc ctgaaaccag
    53161 cggaaccatg gcatttttaa agatgtgttt gtttgaaatt tctttttcag acaaaccttt
    53221 tgcacgagcg aaacgaacaa agtcttgaga ttgcaagtca atcatgtaac gacgaatcca
    53281 aatggctgta ccaggagcac ccaacaaacc aaggatgact gctggtaaaa cgtaagaacg
    53341 ccaatctcca gctcccaaga tagggaatga atctggaagg gaaatagatg atccaatcaa
    53401 tcgaacgatg taaaccaagg caatcgttgg aagagcaagc aagaaggtca aagcccctgt
    53461 tgagaggcta tcaatccaag tgttcttgaa acgagccatg gctgaaccaa gtggcacggc
    53521 aagagcatag gcaagaacca aaccaatcaa accagtaata gcagagctga caatcataga
    53581 tggatattgg taattacttt cagtcgctgt ataaggatca tctttcccat agctagctac
    53641 ttcacgagag tcagcctgac taggtgactt gtaggttctt gagtaaatat ttacagaaga
    53701 cgttttctta cctgttggga actgaacttg ggcagttttg gtttgtcctt gaccttgagt
    53761 aataacctga agaactggtg tattagcata ggttgggtaa gagtcaccta aattcaagtt
    53821 cacaaagttt tgatgaacaa atgggaactg actgttaaag tacaagagat atttatgttt
    53881 agttcctgaa ccgaccaatg accatccgat agctggatca ttttcaaaac gaaggtagcg
    53941 tttcaagtct ggattttcag ggtcttggat tttatttgta tggtcaatgt caatcaagtt
    54001 agcatagaag tgaaaaacac gttcaaaaat tggaatttca cgagtagcat agaattgacc
    54061 actttcagta aattctccca aagtccaacc atgacctaat tgattgatgt acttttcata
    54121 aatagcttta ttggtcgcat ttgcttctac tgttacagaa gaatccatgc tacttgcctt
    54181 ttcttgcaac tctttagtat cgtaatactc aatgtagccc atacgctcaa acacagtatt
    54241 ttcatagtta tcacgtttat cagccgttgt cgcaatttta ttatagttag gatcctgctt
    54301 gaaaatcaat tttcgaggaa ccaaggtata gataatcgtg taggtcaaag tcgttactaa
    54361 gaaaatcgaa accaatgacc gcaaaacacg cataaaaata tattttttca tattatttcc
    54421 tttaaaaatc ccaaaagaac cttctcctca tggagagaaa gttctattag aaattattta
    54481 cttcacatga cttgccaatt ctttttgagc tttctcattt gattcagctt tttctttcaa
    54541 ccatttttca cgagcttttt catactcttc cttagtcacc gctttatctt gtaatttcaa
    54601 atatttgaag taaacatctg accccttaga gcctgtttgc gcagaagctc cagtaaatgg
    54661 aacaattcgt gaaagcactg gtgctgcacc agaagaagcc atagcaggaa taaagagtga
    54721 actatctgtc aaccatgctt gagccgctgc atatttttca taacggacat tcaagtcgct
    54781 tgtctctttg gcagcttcat caactaattt atcgtattct ttcaaaccaa cttgaactac
    54841 tgaagggcta tttggattat caaatcctaa atatgttttt gtagtttcac tgctagttgt
    54901 ttttaaaata tccaggtaag tagatgggtc ttgatagtct ggcccccatg aaactcctcc
    54961 cgatacatcc caatcctcag atgaagcatt ggcagcatag taagtaatat taaggaattc
    55021 atcacttgtc atttgttgaa tatcaacaac gacattttca acaccaagaa ctgtttctac
    55081 agattgttta aaggactgaa tacgagatat atagtttttt gatgcttggt ctactggaac
    55141 gtccagatga ataggaaact gaacgccgtc tgcttctaaa gctttcttag ctttcgcaaa
    55201 ctctgccttg gccttgtcag cattgaataa accatcctgc ccatcagcta aattcacacc
    55261 tttccactca tcaccataag caggaagttg agcagcgact aaatcaccaa aggtcttctc
    55321 accagctgaa acaaagtctg gttttacaaa taaattacga actgctaaag ctgctccatc
    55381 tttaccattg atttgagctg agtaagctga gcgatcaaga gcaaaattca aggcttgacg
    55441 gaaatctttg ttaagcaatg ccttcttagt agctactttc tctgaatctg tagttttaga
    55501 agtatagttg taactttggc gatcaatatt cacacccaga ccagcaatcc cagagcctga
    55561 ttgtgtgtaa tagatattgt ccttgtattc ttctgcaacc ttagaatagt tggagctggt
    55621 agggtaaaga cgggcataac tataagctcc actagtgaag ttacgctcta gcgactcctg
    55681 atctgatcca tcatagtaag ctagattgat agtatctagg tggacatttt ctttatccca
    55741 atattgctca ttttttacaa actctacaga agattttgca gtcaaccctt tcaacaagaa
    55801 tggaccatta taaagcaagg atgtcggatc tgttggttta gcaaaatcgc ttccttttga
    55861 tgtttcgaat tcttcattca gaggccagaa aatagaatag gtcaacttag agttccagaa
    55921 cggttcaggc tggttcaaag tgtattgtaa cgtataatca tcaaccgcct tgacaccaac
    55981 tgttgaaaaa tctgttgaag ttcctgatag ataatctgcc aagcctttaa ccgaattttc
    56041 agctaaatac atagcttctg attttttatc tgctgcgtgt tttaaaccgt tcacgaaatc
    56101 tttagccgtc acctctgcat attcttctcc atcagaggta aaccatttaa cccctttacg
    56161 aatcttataa gtgtaggtca aaccatcctt agagacttcc caatcctctg caactgcagg
    56221 agcaagatta ccgtaattat cgttagtgaa taaaccatca atcccatttg aagtcactac
    56281 tgttgtacta tttttacttg aaatcaggta gtccaaggtt tctgggtctg ctgtataaac
    56341 atagccataa gctttagggg ctgatgaatc agatgatttt gaagaactgc atgctgcaag
    56401 tacacctgct gctaataaaa caagacctgc tgtagcaaat acacgatttt ttttcatttt
    56461 ctactcctct gtttatgtga attatagatt gacaaccatt atatcacatt atccattaaa
    56521 aatcaaacaa attttcagaa tatttaggct tgttggcaca aatttttcat tttttttgaa
    56581 tatatgattc aaattgtcgt tcgaagtgtc aaagactaca gtgaaaatag gaaatttgac
    56641 acagaaattt tggagcttag gaagacatac agtaaaatga aatacggacg gaacaatgtg
    56701 attttggaat tcaaattaaa
//
LOCUS       DBEJKC010000005        49982 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.005, whole genome shotgun sequence.
ACCESSION   DBEJKC010000005 DBEJKC010000000
VERSION     DBEJKC010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 49982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49982
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.005"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            9..89
                     /locus_tag="ACL3G6_000309"
     tRNA            9..89
                     /locus_tag="ACL3G6_000309"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:43..45,aa:Tyr,seq:gta)
     gene            94..164
                     /locus_tag="ACL3G6_000310"
     tRNA            94..164
                     /locus_tag="ACL3G6_000310"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:126..128,aa:Trp,seq:cca)
     gene            179..251
                     /locus_tag="ACL3G6_000311"
     tRNA            179..251
                     /locus_tag="ACL3G6_000311"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:212..214,aa:His,seq:gtg)
     gene            262..333
                     /locus_tag="ACL3G6_000312"
     tRNA            262..333
                     /locus_tag="ACL3G6_000312"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:294..296,aa:Gln,seq:ttg)
     gene            343..426
                     /locus_tag="ACL3G6_000313"
     tRNA            343..426
                     /locus_tag="ACL3G6_000313"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:377..379,aa:Leu,seq:caa)
     gene            complement(537..1268)
                     /locus_tag="ACL3G6_000314"
     CDS             complement(537..1268)
                     /locus_tag="ACL3G6_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGR0544906.1"
                     /translation="MAKLYAISDIHGYLDEFRDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEVYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GMLWKELTSSKIFTNKFPITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYLI
                     DGDVTNSKTIPVLYYDTITQKYHFL"
     gene            complement(1261..1497)
                     /gene="relB"
                     /locus_tag="ACL3G6_000315"
     CDS             complement(1261..1497)
                     /gene="relB"
                     /locus_tag="ACL3G6_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HGR0544907.1"
                     /translation="MNNVVTTQISIQLSQELNSLLNAIVEENNTTKTDFIRQAVIEKI
                     EDMYDIKVADEAYKKWVECGKKATSHEEMMRRYG"
     gene            complement(1713..2150)
                     /locus_tag="ACL3G6_000316"
     CDS             complement(1713..2150)
                     /locus_tag="ACL3G6_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGR0544908.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVASFVATDEE
                     KAVAYLHDVIEDTSLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKKNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRAKKKS"
     gene            complement(2191..3324)
                     /locus_tag="ACL3G6_000317"
     CDS             complement(2191..3324)
                     /locus_tag="ACL3G6_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0544909.1"
                     /translation="MAIRKGKDGNWVVDISNGFDPITLKQRRLVRKGYKTKKEAIEAE
                     HYLRSVELKERFYGAKITIPILYELLKEEDSINHRKASYINTQDNNYNKHIKDYFSMV
                     DNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILLKKIFDVGLRKGYYSSN
                     PAKLIKKLPIEKTKMQFWTVKEFQKFLTLFEPEEYNIKLLFTVLFFTGLRLGEALALT
                     WQDIDFSSNTIHITKSVYVNKGVTHISTTKTKAETRRIVINKKLSQELQDWKKRQKHL
                     LEQFTNNSLTLQVFQNSPITITKNAIEKQYKKIIERDSTLKKIRIHDFRHSHASLLIN
                     QGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDLL"
     gene            complement(3328..3531)
                     /locus_tag="ACL3G6_000318"
     CDS             complement(3328..3531)
                     /locus_tag="ACL3G6_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HGR0544910.1"
                     /translation="MIATVTKNDLIALGFFEGTSKRIIRQGKELLITRGFTVYQNKRI
                     GTIPATIATELLVFDVQNSTLKE"
     gene            complement(3545..4327)
                     /locus_tag="ACL3G6_000319"
     CDS             complement(3545..4327)
                     /locus_tag="ACL3G6_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HGR0544911.1"
                     /translation="MTSYNKKIVRTSSYIEIWEYEKPIFSKGKSILDTNTENKEKAKR
                     RTFDELTPLEQEQRLERMKKTRLEAKWNLLRLVDCNFDDTTSFLTLTTKENISDRNHF
                     KDSLKTFIKRFNYHIFNTKKSKLKYIAVLERQKRKAWHSHILLFSVPYIPHKQLLELW
                     GHGAVWINKVDVDSKENRGRYVTKYFEKGIGQELLENFGKQAYFSSRNLKKPDEDKFY
                     TYEDFNYDSSVVLYETEYTSKVYKYGQYFDNHVKYKKIRLDE"
     gene            complement(4511..5284)
                     /locus_tag="ACL3G6_000320"
     CDS             complement(4511..5284)
                     /locus_tag="ACL3G6_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR0544912.1"
                     /translation="MKTLLIGDLHLKSQLILPIVDKIIQTHNIKRIIFLGDYVDLHGQ
                     TNNIQLYAKDLTFLYSWKIDKEQNGIDVINLIGNHDAYYLLGEQAPFSIQNLEVFFAV
                     KELLQDLKLQIAYQLDDYLVSHAGFNLIFDPKEWHFNLYTKEYEEELDILAYTIGPMR
                     GGKALGGSPLWAHFRELELLPNQDFPKQIVGHTPKESIDISKNVIGIDTFSLYIDKDN
                     KYQFIGNGDLLVYDQGHLEIISTNWATDETLKQLSKPQI"
     gene            complement(5328..6098)
                     /locus_tag="ACL3G6_000321"
     CDS             complement(5328..6098)
                     /locus_tag="ACL3G6_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGR0544913.1"
                     /translation="MAIYYSVSDIHGHYNEFIKSLNKIDLSDKQSKLILLGDYIDYGS
                     QSFQVISKIIELEKIYPKQIITLFGNHEEWFYDWLILDNPTASAFPETIKSFFSTEEL
                     NYILKTNPNNFETGVRNEIRNNDKYIPFINWFQKRYEDSRYFETENQIFVHAGIDEEA
                     NNLWKDLTSPEIFTNKFPITTGRFYKDIISGHFASWEVAKDKSYLGKIYHDSKSHYFI
                     DGDVKNSKTIPVICYDTVKKSYQYSKNTSLLPKKFDRA"
     gene            complement(6117..6506)
                     /locus_tag="ACL3G6_000322"
     CDS             complement(6117..6506)
                     /locus_tag="ACL3G6_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544914.1"
                     /translation="MQIFTYNDFLKDKEIVTFEQAEIILDELIKSSNIYDPEFQAYWK
                     ELIEYSAKYAEMRGKWRILTKEEQDTLDDTRTNIHNRIRDNLISIRGLAQINNKDTSW
                     FDKFHNDRKRMGDFANYINYIYAVNSR"
     gene            complement(6544..6858)
                     /locus_tag="ACL3G6_000323"
     CDS             complement(6544..6858)
                     /locus_tag="ACL3G6_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544915.1"
                     /translation="MKLNDFLKPELLGNKFIAVKGYTEVLDRETNKPVALRLNVSIQD
                     EDSDFFMEMIQVKVNTLSPTASVQEMANNKTCPVTLKDLNVGQYNGNLWFSCSNVILI
                     TK"
     gene            complement(6948..8270)
                     /locus_tag="ACL3G6_000324"
     CDS             complement(6948..8270)
                     /locus_tag="ACL3G6_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HGR0544916.1"
                     /translation="MFKLRQSADLTRNNIISCYKLKIMHWLILSISACILFSTIVNIR
                     APTFVQILFIFLGGFIIYKIHLKIKIFRYDLEHYLIIRESLLYVLHTNRLYTTSKDGS
                     GYEKIVRSAVLEYEIDRQKGHVLIKALITGDEFSKKVQSLDDVLSDVLELELEEKIIR
                     PSFIEYHFYYIKPKRLVLQSHSQRQEIDSLDIDLGYGVNYNPVKCSHILVSGGTGSGK
                     SVLISVLILEFLKRQSTVYIADPKNSDLGSLSHYFGNKYVATTPNNIARIVRVVVEEM
                     QERYQVMRDNFQYGSNFTNHGFKPVWLIFDEMGAFQATGSDKKSREIITEVMDGIKQI
                     ILLGRQSGIFILVSAQQVNASTTLSTELRDNLGLRIALGANSSEGYHMVFGSATPDKL
                     KPIEEKGSGYLYIQGSGKESAQYWESPYLDTTQFDFIKELQLYVTKSK"
     gene            complement(8276..8494)
                     /locus_tag="ACL3G6_000325"
     CDS             complement(8276..8494)
                     /locus_tag="ACL3G6_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544917.1"
                     /translation="MSDNLKAYLFLLGFVILAGIAIFIFPQGHFFSNSILILGCIPLL
                     ISTYYFAKIKLLGFYELLKELLDKIKGI"
     gene            complement(8534..9289)
                     /locus_tag="ACL3G6_000326"
     CDS             complement(8534..9289)
                     /locus_tag="ACL3G6_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGR0544918.1"
                     /translation="MIQLTASTWNINLRSRKGKQIPEMIAQELAQQNSDIICLTEYVK
                     TDNHSQFCSSLQTNGYTIFEDVRTIDFGNEILIAIKSDLVNDCQVITIDNDDNNPNFL
                     HVRVTIEGQELNIIGVRIKIGGENVFEDFKHRKTQLDKLIFNLPIHENTIILGDFNNG
                     FFKQNDDTHSYQGKPREFYSYPLLKSEMNKAGLTVHTPSEENSWKYCKLDHIIGNIPI
                     SNVCYSWRFLENPDYQNKVGFPDHAILSATISL"
     gene            complement(9717..10220)
                     /locus_tag="ACL3G6_000327"
     CDS             complement(9717..10220)
                     /locus_tag="ACL3G6_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544919.1"
                     /translation="MTQFQVRISGEAAYYLRMLKEKYETSEGINITKATILTRAFQNS
                     KTVTNWTKVVQDNSISLKNIYPVEEKELKLNVALSDEVAEGIKKYKEILPSATNTQSV
                     TLGVCVKFLLKAELMTQLNHDISEPEKDFDKKFSILEKQLLEIVAPVNHKLLSDTIWN
                     FKNNFIK"
     gene            10649..11926
                     /locus_tag="ACL3G6_000328"
     CDS             10649..11926
                     /locus_tag="ACL3G6_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HGR0544920.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKIDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFSLNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            12002..13486
                     /gene="thrC"
                     /locus_tag="ACL3G6_000329"
     CDS             12002..13486
                     /gene="thrC"
                     /locus_tag="ACL3G6_000329"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HGR0544921.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGETVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNMQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYELDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVRHKTTVAAADMQVAVEAYLGL"
     gene            13547..14827
                     /locus_tag="ACL3G6_000330"
     CDS             13547..14827
                     /locus_tag="ACL3G6_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGR0544922.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            14831..15451
                     /locus_tag="ACL3G6_000331"
     CDS             14831..15451
                     /locus_tag="ACL3G6_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0544923.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLDPEKTY
                     YIGDRTLDVEFAKNSGIQSINFLESSFEGNHRIQALADISRIFETK"
     gene            15617..16795
                     /locus_tag="ACL3G6_000332"
     CDS             15617..16795
                     /locus_tag="ACL3G6_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGR0544924.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASNSEVAETV
                     TAAEEVAPSTGTSVPEEQTAETTRPVEEVAPQATTLAEKQETQVSSQTESAVEATTMP
                     VEEKATETTATSSEAKEVASSNGATAAVSTYQPEETKTISTTYEAPAAPDYAGLAVAK
                     SENAGLQPQTAAFKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPESSELGDKIA
                     EYAIQNMASRGISYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG
                     "
     gene            17223..17646
                     /locus_tag="ACL3G6_000333"
                     /pseudo
     CDS             17223..17646
                     /locus_tag="ACL3G6_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
     gene            17657..18025
                     /locus_tag="ACL3G6_000334"
     CDS             17657..18025
                     /locus_tag="ACL3G6_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HGR0544925.1"
                     /translation="MSIITIILTTIVAWEHFYIFYLESIATQSDATSRVFNMEREELA
                     HPSVSLLFKNQGIYKALLGVCLLYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            18132..18750
                     /locus_tag="ACL3G6_000335"
                     /pseudo
     CDS             18132..18750
                     /locus_tag="ACL3G6_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(18778..19635)
                     /locus_tag="ACL3G6_000336"
     CDS             complement(18778..19635)
                     /locus_tag="ACL3G6_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HGR0544926.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            19765..20907
                     /gene="tgt"
                     /locus_tag="ACL3G6_000337"
     CDS             19765..20907
                     /gene="tgt"
                     /locus_tag="ACL3G6_000337"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HGR0544927.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            21008..22825
                     /locus_tag="ACL3G6_000338"
     CDS             21008..22825
                     /locus_tag="ACL3G6_000338"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGR0544928.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            22978..24129
                     /gene="nagA"
                     /locus_tag="ACL3G6_000339"
     CDS             22978..24129
                     /gene="nagA"
                     /locus_tag="ACL3G6_000339"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HGR0544929.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            24292..25350
                     /locus_tag="ACL3G6_000340"
     CDS             24292..25350
                     /locus_tag="ACL3G6_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HGR0544930.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            25501..25866
                     /locus_tag="ACL3G6_000341"
     CDS             25501..25866
                     /locus_tag="ACL3G6_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HGR0544931.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            25942..26883
                     /gene="comGA"
                     /locus_tag="ACL3G6_000342"
     CDS             25942..26883
                     /gene="comGA"
                     /locus_tag="ACL3G6_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HGR0544932.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDIETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            26831..27847
                     /gene="comGB"
                     /locus_tag="ACL3G6_000343"
     CDS             26831..27847
                     /gene="comGB"
                     /locus_tag="ACL3G6_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HGR0544933.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            27849..28175
                     /gene="comGC"
                     /locus_tag="ACL3G6_000344"
     CDS             27849..28175
                     /gene="comGC"
                     /locus_tag="ACL3G6_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HGR0544934.1"
                     /translation="MKKMMTFLKKAKVKAFTLIEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQADGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            28168..28572
                     /gene="comGD"
                     /locus_tag="ACL3G6_000345"
     CDS             28168..28572
                     /gene="comGD"
                     /locus_tag="ACL3G6_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HGR0544935.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            28535..28837
                     /gene="comGE"
                     /locus_tag="ACL3G6_000346"
     CDS             28535..28837
                     /gene="comGE"
                     /locus_tag="ACL3G6_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGE"
                     /protein_id="HGR0544936.1"
                     /translation="MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQE
                     EAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            28800..29261
                     /gene="comGF"
                     /locus_tag="ACL3G6_000347"
     CDS             28800..29261
                     /gene="comGF"
                     /locus_tag="ACL3G6_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HGR0544937.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            29239..29685
                     /gene="comGG"
                     /locus_tag="ACL3G6_000348"
     CDS             29239..29685
                     /gene="comGG"
                     /locus_tag="ACL3G6_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HGR0544938.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKNQKRSLKRKRIPSQFNYNALNPE"
     gene            29788..30382
                     /locus_tag="ACL3G6_000349"
                     /pseudo
     CDS             29788..30382
                     /locus_tag="ACL3G6_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            30443..31396
                     /locus_tag="ACL3G6_000350"
     CDS             30443..31396
                     /locus_tag="ACL3G6_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0544939.1"
                     /translation="MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFTEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGF
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            31447..32637
                     /locus_tag="ACL3G6_000351"
     CDS             31447..32637
                     /locus_tag="ACL3G6_000351"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HGR0544940.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADVIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            32638..32769
                     /locus_tag="ACL3G6_000352"
     CDS             32638..32769
                     /locus_tag="ACL3G6_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544941.1"
                     /translation="MKLKKYSIQGVGKVIFPASFSDEIVQNLAMIGFFEKYGIIVVI"
     gene            32786..33157
                     /gene="rnpA"
                     /locus_tag="ACL3G6_000353"
     CDS             32786..33157
                     /gene="rnpA"
                     /locus_tag="ACL3G6_000353"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HGR0544942.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            33132..33956
                     /locus_tag="ACL3G6_000354"
     CDS             33132..33956
                     /locus_tag="ACL3G6_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGR0544943.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            33975..34961
                     /gene="jag"
                     /locus_tag="ACL3G6_000355"
     CDS             33975..34961
                     /gene="jag"
                     /locus_tag="ACL3G6_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HGR0544944.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            35012..35635
                     /locus_tag="ACL3G6_000356"
     CDS             35012..35635
                     /locus_tag="ACL3G6_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HI_0552 family protein"
                     /protein_id="HGR0544945.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            35766..37223
                     /locus_tag="ACL3G6_000357"
     CDS             35766..37223
                     /locus_tag="ACL3G6_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR0544946.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            37246..37527
                     /locus_tag="ACL3G6_000358"
     CDS             37246..37527
                     /locus_tag="ACL3G6_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0544947.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            37604..38089
                     /locus_tag="ACL3G6_000359"
     CDS             37604..38089
                     /locus_tag="ACL3G6_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0544948.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            38106..38771
                     /locus_tag="ACL3G6_000360"
     CDS             38106..38771
                     /locus_tag="ACL3G6_000360"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HGR0544949.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDIFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            38775..39638
                     /locus_tag="ACL3G6_000361"
     CDS             38775..39638
                     /locus_tag="ACL3G6_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HGR0544950.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            39640..40344
                     /locus_tag="ACL3G6_000362"
     CDS             39640..40344
                     /locus_tag="ACL3G6_000362"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HGR0544951.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            40523..42196
                     /locus_tag="ACL3G6_000363"
     CDS             40523..42196
                     /locus_tag="ACL3G6_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR0544952.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            42308..43399
                     /gene="ulaG"
                     /locus_tag="ACL3G6_000364"
     CDS             42308..43399
                     /gene="ulaG"
                     /locus_tag="ACL3G6_000364"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HGR0544953.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            43513..45489
                     /gene="tkt"
                     /locus_tag="ACL3G6_000365"
     CDS             43513..45489
                     /gene="tkt"
                     /locus_tag="ACL3G6_000365"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGR0544954.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGINTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            45606..45905
                     /gene="yajC"
                     /locus_tag="ACL3G6_000366"
     CDS             45606..45905
                     /gene="yajC"
                     /locus_tag="ACL3G6_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGR0544955.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            45952..46380
                     /locus_tag="ACL3G6_000367"
     CDS             45952..46380
                     /locus_tag="ACL3G6_000367"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HGR0544956.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            46382..46792
                     /locus_tag="ACL3G6_000368"
     CDS             46382..46792
                     /locus_tag="ACL3G6_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HGR0544957.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            47092..49743
                     /gene="adhE"
                     /locus_tag="ACL3G6_000369"
                     /gene_synonym="adhC"
     CDS             47092..49743
                     /gene="adhE"
                     /locus_tag="ACL3G6_000369"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HGR0544958.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSVHA
                     ARIVRDAAIAAGAPENCVQWITEPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFRPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        15271 a         8756 c        10514 g        15441 t
ORIGIN      
        1 tatattttgg aagggtagcg aagaggctaa acgcggcgga ctgtaaatcc gctccttcgg
       61 gttcgggggt tcgaatccct ccccttccat tttacgggca tagtttaaag gtagaactaa
      121 ggtctccaaa accttcagtg tgggttcaat tcctactgcc cgtgttaata gaattatggc
      181 gggtgtggtg aagtggttaa cacaccagat tgtggctctg gcatgcgtgg gttcgatccc
      241 catcactcgc ctattttata ttggggtata gccaagcggt aaggcaaggg actttgactc
      301 cctcatgcgt tggttcgaat ccagctaccc cagttactat ttgccggcgt ggcggaattg
      361 gcagacgcgc tggactcaaa atccagtgtc cgcaaggacg tgccggttcg accccggccg
      421 ccggtatagt attaaagaca aggttttagg accttgtctt tttgttatgt cataagaaat
      481 ttcttggaat tgttactaat aattactaat ttcatataaa agcacatgat taaaagttat
      541 agaaagtgat atttttgggt aattgtatca tagtaaagaa caggtattgt tttgctattc
      601 gttacatctc catcaattaa gtaatgactt ttactatcat agtaaatctt acctaggtat
      661 cttctatctt tagctacttc ccaagaagca atatggcccg aaataatagc tttatgaaat
      721 ctaccagtgg taattggaaa tttgtttgta aatatctttg aactcgttag ttctttccaa
      781 agcattcctg cttcttcatc aatgcctgca tgaacaaaaa tttgggtatc agtttcataa
      841 tagcgtttat ccctatatcg ctttttaaac cagtttataa atgggttgaa tttgatatta
      901 tttttaattt catttctaac acctgtttca aagttgttag cattcgattt aaaaatatag
      961 ttcaattcct ctggagagaa gaagcttttt attgtttctg gaaatgctga agcagtaggt
     1021 ttatctaaaa tcaaccaatc ataaaaccat tcttcatgat tccctagaag agtaataatt
     1081 tgattaggat aaacctcctc aagttcgatt attttggaaa tgacttgaaa agattgaagt
     1141 ccattatcaa gataatctcc tagtaaaaat aggcgattat ctttatcgtt taaatttact
     1201 ttattgagag cgtctctgaa ttcatccaag tatccatgta tatcagatat tgcgtataat
     1261 ttagccatag cgtctcatca tttcttcatg tgaggtagct tttttgccac attcaaccca
     1321 ttttttataa gcttcatcag cgaccttaat atcatacata tcttcaattt tctctataac
     1381 agcttgtcta ataaagtcag tctttgttgt attattttct tcaacaatag catttaataa
     1441 agaatttaac tcttgactaa gttgaataga aatttgtgta gtaacaacat tattcatata
     1501 acagccacct aatagttatt ttagatacat tatactccta gtctaaaagt ttctcaataa
     1561 aaaatttcac tttttatagt tatttatttt aataaaattg tagtatctgc aaggatgtgc
     1621 cagttcgaga ccgaccgcca gtatagtaat aaagacaaag tttataagcc ttgtcttttg
     1681 ttttctcttt ataaaatttt atagtttagt tactaacttt ttttctttgc tcttaaaaat
     1741 ctaatagcag aactgtattt cttatttctc tctaagtctt tttcagtaat taatggtagt
     1801 cttgttaaat ctgaattatg ccgtaaatcc gccaacttta caactctagc gagttcattt
     1861 ttctttacta gattgagata agattgataa tcttgtcctt ttttctttgt gagtatatcg
     1921 acggcttcta taatgttttt tgaaaaacct tcctttttta ggtctagtag ggttagtgaa
     1981 gtatcttcaa ttacatcatg tagataggcg acagctttct cttcatcagt tgcgacaaaa
     2041 ctagctactg tttcagggtg tttaatgtag tcaattcctg ctctatcaat ttgtccaaag
     2101 tgtgcttttt tagctacttc atgtgctttt attacttgtg atgtatccat gatttaatta
     2161 taaactttcc atttataaaa ctcaattact ttatagtaaa tcatctagtt tatcagctaa
     2221 atccttttgc ttacttgggt acaagtgaga gtaggtatca atcgtggttg ttatagaagc
     2281 atgtcctagt cgctctttta caactagata atcttcccct tggttaatca gcagggaagc
     2341 gtgtgagtgc ctaaaatcgt gtatgcgtat cttttttagt gtgctatcac gttcaatgat
     2401 tttcttgtac tgcttttcaa tagcattttt tgtaattgtg ataggactat tttgaaacac
     2461 ttgtaatgtt aggctattgt tggtaaattg ctctaataga tgtttttgtc gctttttcca
     2521 atcttgtaat tcttggctta attttttatt gataacaatt cttcttgttt ctgctttagt
     2581 ttttgttgtg ctgatatgag ttactccttt attaacatag acagacttcg tgatatgaat
     2641 tgtattactt gaaaagtcga tgtcttgcca tgttagggca agagcttccc caagtcttaa
     2701 tcctgtaaag aatagaacag taaagagtag tttgatattg tattcttcgg gttcaaatag
     2761 tgtcaaaaac ttctgaaatt ctttgactgt ccaaaattgc atttttgttt tttcaattgg
     2821 caactttttt attaattttg ctggattgga ggagtaatag ccttttcgca aaccaacatc
     2881 aaaaattttt ttgagtaaaa tcatgatttt gttaatagta tttgtgctta acggtttatc
     2941 agaattttta gctacttttt gcctaagatg ttctctaaat tggtagatgt cttcataggt
     3001 tagttttccg acattatcga ccatagaaaa ataatctttg atgtgtttgt tgtaattatt
     3061 atcttgtgta ttgatatagc ttgcttttcg atgatttata ctatcttcct ccttaagtag
     3121 ttcatatagt atggggatag ttattttagc tccataaaag cgttctttta actctacact
     3181 tcgtaagtag tgttctgctt caatagcttc ttttttcgtc ttatagccct ttctgacaag
     3241 tctacgttgc tttagtgtta ttgggtcaaa accgttgcta atatcaacta cccaattacc
     3301 gtctttacct tttctaattg ccatatttta ctccttgagg gtactgtttt gaacatcaaa
     3361 aacgagtaat tcggtagcaa tagtagcagg tatagtacca attcgcttgt tctgatagac
     3421 tgtaaagcct cgggttatca gtagctcttt cccttggcgg ataatacgtt tagatgttcc
     3481 ctcaaagaaa ccgagggcaa ttaggtcatt cttagtaaca gttgctatca tgtgacttac
     3541 tcctttattc atctagtctt attttcttgt actttacatg attatcgaaa tactgaccgt
     3601 atttatagac cttactagtg tattccgttt catatagcac gactgaacta tcatagttaa
     3661 aatcttcata agtgtaaaat ttatcttcat caggcttttt caagttgcgt gatgaaaaat
     3721 aggcttgctt tccgaagttt tccaacaatt cttgtccaat acctttttca aaatactttg
     3781 tgacatatcg accgcgattt tctttgctgt cgacgtcaac tttatttatc catactgcac
     3841 catgccccca aagttctaat aattgcttat gtggaatata gggaacactg aatagcaaaa
     3901 tatgactatg ccatgcttta cgtttttgcc tctctaatac tgctatatat tttaatttac
     3961 ttttcttggt attaaaaatg tggtagttaa agcgtttaat aaatgttttg agtgagtctt
     4021 tgaagtggtt tctatcgctg atattttcct tagtggtcag tgtaagaaaa gaagttgtat
     4081 catcaaaatt acaatcaact agacggagta agttccactt ggcttctaag cgagtcttct
     4141 tcatacgttc aagacgttgt tcttgttcta ggggtgttag ttcatcaaat gttctgcgtt
     4201 ttgctttttc cttgttttca gtattagtat ctaaaataga ttttcctttt gaaaatattg
     4261 gcttttcata ttcccaaatt tcaatatagg aagaagtgcg gactattttt ttattatatg
     4321 aggtcataaa aaatagttcc ttttaggttg gctttcgcca aaagattgtc tatataataa
     4381 ataaactagg aggagcaaag ctcctccaca cttctatcat gtgtttctaa gcatcgctcc
     4441 gctaaacacg cttccagctt gctgacctcc agtcagcagt ttcgcttagt cacatgatga
     4501 gaagtagtag ttaaatttgt ggtttagata attgttttaa tgtttcgtct gtagcccagt
     4561 tggttgaaat gatttcaaga tggccttggt catagactag caaatctccg ttaccaataa
     4621 attgatattt attatctttg tcaatatata atgaaaaagt atctatacca ataacatttt
     4681 tagaaatatc aatagattct ttaggggtat gtccaacaat ttgtttagga aagtcttggt
     4741 tgggaagcaa ttctaattct ctaaaatgtg cccataaagg agaaccccca agagctttcc
     4801 caccacgcat tggtcctatt gtataagcta ggatatctaa ttcttcttca tactctttgg
     4861 tataaaggtt aaaatgccat tcttttgggt caaatatcag attgaaacca gcgtgactga
     4921 ctaaataatc atctagttga taagctattt gtaatttcaa atcctgcaac aattctttta
     4981 ctgcgaaaaa cacttctaaa ttttgaattg agaaaggagc ttgttctccc agtaaataat
     5041 aagcatcatg attacctata agattaatta catctattcc gttttgctct ttatctattt
     5101 tccaagagta taaaaaagtg aggtctttgg cataaagttg gatattgtta gtttgaccat
     5161 gtaaatcaac ataatcacca agaaaaatga ttctcttaat gttatgtgtt tggataattt
     5221 tgtcaacaat gggtaaaatt agttgagatt ttaaatgtaa gtcaccaatt aataatgtct
     5281 tcatatatat tcccctcttt atttttgata ttagtctaag aatagaatta agctctatca
     5341 aattttttag gcaatagaga agtgtttttt gaatattgat aggatttttt aactgtatca
     5401 tagcagataa caggtattgt tttgctattt tttacatctc catcaataaa gtaatgactt
     5461 ttactatcat ggtaaatctt acctaggtaa cttttatctt tagctacttc ccaagaagca
     5521 aaatgcccag agataatatc tttataaaat ctaccagttg taataggaaa tttgttggta
     5581 aatatctctg gactcgttag gtctttccaa agattattag cttcttcatc aatgccagca
     5641 tggacaaaaa tttgattttc tgtttcaaaa taacgactat cttcatatcg tttttggaac
     5701 cagtttataa atggaatata cttatcatta tttctaattt cgtttctaac acctgtttca
     5761 aagttgttag gatttgtttt taaaatatag ttcaattcct ctgtagagaa gaaactcttt
     5821 attgtttctg gaaacgcaga agcagtagga ttatctaaaa tcaaccaatc ataaaaccat
     5881 tcttcatgat ttccaaaaag tgtaataatt tgttttggat aaatcttttc aagttcaatt
     5941 attttagaaa tgacttgaaa agattgagaa ccgtaatcaa tatagtctcc aagtaagata
     6001 agtttacttt gtttatcaga taaatctatt ttattgagag atttaataaa ctcattgtag
     6061 tgcccatgta tatcagatac ggaataataa attgccatat aagattcttt ctataatcaa
     6121 cgtgaattta cagcgtatat gtaatttata taattagcaa aatcacccat acgttttcta
     6181 tcgttatgaa acttatcgaa ccaagaggta tctttgttat tgatttgagc caagcctcta
     6241 atagatataa ggttatctct aattctatta tgaatattag ttcttgtatc atcaagtgta
     6301 tcttgctctt cttttgtaag tattcgccat tttcctctca tttcagcata cttcgcactg
     6361 tactcgataa gttctttcca gtatgcttga aattcagggt cataaatgtt tgatgatttt
     6421 ataagttcat ctaaaattat ttcagcttgt tcaaaagtta cgatttcttt gtcttttaga
     6481 aaatcgttat aagtaaaaat ttgcatagta agctccttta atttttgaaa taattataac
     6541 acattattta gtaattagaa ttacattaga acaagaaaac cataaatttc cattgtattg
     6601 acctacgttt aaatctttta gagtaacagg acaggtttta ttatttgcca tttcttgaac
     6661 agaagcagta ggggataatg tatttacttt gacttgtatc atctccataa agaaatcaga
     6721 atcctcatct tgaattgaca cgttaagtcg taaagctacg ggcttattag tctctctgtc
     6781 taatacttct gtatagcctt ttactgctat aaatttgttg ccaagcagtt ctggctttaa
     6841 aaaatcattt agcttcatgt gtacctcttt tctatcatcg cagagcgatg aggaacagat
     6901 atttttgctg aaaatctatt aaatttaagc aaaaatatct gttgaaatta ttttgacttt
     6961 gttacgtata attgtagttc ttttataaaa tcgaattgag ttgtatcaag ataagggctt
     7021 tcccagtatt gggcagattc tttaccagag ccttgtatat aaagatagcc tgaacctttt
     7081 tcttcaatag gttttaactt atcaggagta gccgaaccaa agaccatgtg atagccttca
     7141 ctagaattag caccaagagc aattctcaat cctaaattat ctctgagttc agtacttaaa
     7201 gtagtactag catttacttg ttgggcagac actaggataa aaatgcctga ctgtcttcca
     7261 agtagaatga tttgtttaat cccatccata acttcagtga taatctctct tgatttttta
     7321 tctgaacctg tagcttgaaa tgctcccatt tcatcaaata taagccatac tggcttaaat
     7381 ccatggttag taaaatttga accatactga aagttatcac gcatgacttg atatcgttcc
     7441 tgcatttcct caactacgac tctcacaatg cgagctatat tatttggggt ggttgctacg
     7501 tatttatttc caaagtaatg agacaagcta cctaggtcag agttcttagg gtcagctata
     7561 taaactgttg attgacgttt tagaaattct aaaatcaaaa cagatataag cacggatttc
     7621 ccacttccag ttccacccga tactaaaata tgtgagcatt tgacaggatt ataatttaca
     7681 ccatatccta aatctatatc aaggctatct atctcttgtc tttggctgtg agattgtaga
     7741 actaaccttt ttggttttat gtaatagaaa tgatattcta taaaactagg tcgaataatc
     7801 ttttcctcaa gctctagttc aagcacgtca gaaagtacat catcaagaga ttgaactttt
     7861 ttactaaatt catcgcccgt tataagagct ttgataagaa catgaccttt ttgtctatct
     7921 atctcgtatt ctaatactgc acttctaacg attttttcat agcctgaacc atctttagat
     7981 gtggtataaa gtctgtttgt gtggagtaca taaagtaagc tctcacgtat aataaggtaa
     8041 tgctctaagt catatcgaaa aatttttatt ttcagatgaa ttttatagat aataaatcca
     8101 cctaaaaata tgaagagaat ttgaacaaaa gttggagccc taatattaac aatagtggaa
     8161 aatagaatgc aggcagagat acttagtatc agccagtgca ttatttttaa cttataacag
     8221 gaaattatat tgtttcttgt taaatcagca ctttgtctta atttaaacat attagttaga
     8281 taccttttat tttatctaaa agctctttta aaagttcgta aaaccctaag agcttgattt
     8341 ttgcgaaata atatgttgag ataagtagtg gaatacaccc aaggataagg atagaattcg
     8401 aaaagaaatg tccttgaggg aatataaaaa ttgctatgcc agctaatatc acaaatccta
     8461 aaagaaatag atatgctttt aaattatcac tcatttcatt acctcctcta ataagcaatt
     8521 attttaagga aaactataaa gatatagtcg ccgataaaat agcgtggtcg gggaaaccga
     8581 ctttattttg ataatcagga ttttctaaga atctccaaga ataacacaca ttagaaatag
     8641 gaatgtttcc tataatatgg tctaatttac aatatttcca agagttctcc tcagacggag
     8701 tatgtacagt taaacctgct ttattcattt ctgattttag taatggatag gagtaaaatt
     8761 ctctaggttt accttgatag gaatgagtat catcattctg cttgaaaaag ccattattaa
     8821 agtcacctag aataattgtg ttttcatgaa ttggtaaatt gaagattagc ttgtctagtt
     8881 gtgtttttct gtgtttgaaa tcttcaaaaa cattttcccc tcctatcttg atacgaactc
     8941 caataatgtt taattcttgt ccttcaattg tcactctaac gtgtaaaaag tttggattat
     9001 tatcatcatt atcgatagta atgacttggc aatcattaac taaatcactc tttattgcaa
     9061 taagaatttc atttccaaaa tctatagtac gcacatcttc aaagattgta taaccattag
     9121 tttgaaggct agaacagaat tgagaatgat tatctgtttt tacatactct gtcagacaga
     9181 taatatctga attttgctga gctagttcct gcgcaatcat ttcaggaatt tgttttcctt
     9241 ttcttgaacg tagatttata ttccaagtgg atgctgtaag ttgtatcata aaatttcctc
     9301 ctaaaagtta gtccgcagga ggaggcacct cctcctgcta tccttcgaat ccatcaaaga
     9361 tttctcctag ttcgtcttca tcatagtagc tttccaattc ctcatagaag taatctaagg
     9421 cttcttggtc aaaaaagttc attgctattc ctcctctcag tatttttttg tacattttaa
     9481 ttgtacaaaa ttaaaagaag aaagtcaaca aaaaagtata ctttaatttc caaaatgtac
     9541 aaatttaata aaaaaagaat gagtctggga caaaaagatt ttgattttag gaattcttta
     9601 ttataaattt taaaaatcga tagattatac aaaaaagcga acaagacaga attctgagta
     9661 tcagataact cgttttgttc gctttttata tttaagatta gacttttgtt ccagactcat
     9721 tttataaaat tatttttgaa attccatatg gtatcagaaa gtaatttgtg gttgactggt
     9781 gcaacgattt caagaagctg tttttctaga atagagaatt tcttgtcaaa atctttttca
     9841 ggttctgaaa tatcgtgatt taattgggtc atcaattctg ctttaagaag aaatttaaca
     9901 catacaccta aagttacact ttgagtattt gtggcactag gcaatatttc tttatatttt
     9961 ttaattcctt ctgctacttc atcggacagt gcaacgttca attttaattc cttttcttcc
    10021 actggataaa tattttttaa agagatagag ttatcttgta caacttttgt ccagtttgtt
    10081 acagtctttg aattttgaaa cgcacgcgtt aaaatggtag ctttagttat attgatacct
    10141 tctgaagttt catatttctc ttttagcatt cttaaatagt aagctgcttc accagatatt
    10201 cggacttgaa attgtgtcat tattagtacc tccgtattgt attataccat ttgtacatta
    10261 aaaggacaat gtataaacga ataatctacc ttctcgttca agcattttta caagtttagt
    10321 aatcttgttg aagatgcatt ccatgtgtta cgtttaaaaa agggaattaa agtaatctag
    10381 ttcctaaaag gttactaaaa ataaaaaaac tatcgttttt gtgatagagg taactttttg
    10441 aaaaggctat ttgactggct ttatatactt atgaaatgtt aagagcccaa ctcaaaatcc
    10501 agtgtccgca aggacgtgcc ggttcgaccc cggccgccgg tatagtatag tgttaggaac
    10561 gttgttattc ttcgttcctt ttttatatta tttttggtat aattatagtt attcaaattt
    10621 tatttagatt aagaaagtgt aggggagtat gtcttgttct atcgatttat taaaacatcg
    10681 gtatttgaaa aatattaaag aaaatcctga attgtttgtc ggaattgagt tggagtatcc
    10741 tgttgcaagt ttagaagggg atgctacaga tgttgaagtt ataaaggatc tatttcatta
    10801 tttagtttct actttggatc tcaccgtagc aaagatagat gattttggca atctgatcca
    10861 gttagtagat ccgataagtc aggatgctat tttatttgaa gtttcctata caacgattga
    10921 gtttgcattt ggtaaggctg aaacgattca agaggtcgaa aatcgtttca ataattatat
    10981 gaatgtaatt cagagaaagt tagctgaatc aaatcatgct attgttggct gtggtatcca
    11041 tcccaactgg gataaaaatg agaattgtcc agtggcttat ccacgctatc agatgttgat
    11101 ggattatttg aatttgagta gaaatattat taaatcagat ttacatcatt tccctgaata
    11161 tggtactttt atctgtggga gccaggttca gctggatatt tcaaaaacca actacttacg
    11221 ggtgattaat gcttttactc aaattgaagc ggctaaggct tatttatttg caaactctga
    11281 gttttcgggt gcggattggg atacgaaaat ttcaagggat attttctggg aagaatctat
    11341 gcatggtatc tatccagaga atgttggggt caatgctaga ctccttaatg atgaagctga
    11401 tttttttgac tatctaaatc attctgcgat ttttactgcg gaacgtgatg ggcagaccta
    11461 ttatttttat cctattcagg ctggggacta tttggctacg cctgaaatcc aagcattttc
    11521 tctgaatggg gatgaggtta ttatttaccc ccaagagaag gattttgaaa ctcatcgtag
    11581 ttaccagtac caagacttaa cgactcgagg aacagttgag tttcgtagtg tgtgtacaca
    11641 gccacttgat agaacttttg cttctgcagc ttttcacttg ggattattgg ttaatttaga
    11701 caagttagaa gcttacttag aaacagcacc tttctttaaa gtatttggtt atgattacaa
    11761 gtctttaagg agacaatttt ctaagaaaaa tcttacagat gaggaagaaa ctacgattat
    11821 tgaattttcc aaagacttac tcctactagc tgaggaggga ctagtggtga gaaataagga
    11881 agaaatgacc tatttacagc ctttgagaga agaattgagc ctataatttc tcttataaag
    11941 ggagaatttt ctgaaaaatc atgatataat ggacgagact atagataaag gatagagagt
    12001 aatgacatta gtttatcaat caacgcgtga tgccaacaat acagtaactg ccagtcaagc
    12061 aattttgcaa ggtttggcga cggacggcgg tttgtttaca ccggttactt atccaaaggt
    12121 agatttggac tttgacaaat tgaaagatgc ttcttaccag gaagttgcta agctagtttt
    12181 gtcagcattt ttagatgact ttacagctga ggagttggac tactgtatca acaatgccta
    12241 cgatagcaaa tttgatactc cagctattgc accattagtg aaattagatg ggcaatacaa
    12301 tttggaactt ttccatggtt caacgattgc ctttaaggat atggccttgt ctattttgcc
    12361 atactttatg acgactgctg ctaagaaaca tggtttggag aacaagattg ttatcttgac
    12421 agcgacatct ggtgacacgg ggaaagctgc tatggcgggg tttgcggatg tgcctggtac
    12481 tgagattatc gtcttttatc caaaggatgg tgtcagcaag attcaagagt tacaaatgac
    12541 cactcagact ggcgacaata ctcatgttat tgctattgat ggtaactttg acgatgcgca
    12601 aacaaatgtg aagcacatgt ttaacgatgt ggctcttcgt gaaaaattga ctaccaacaa
    12661 gttgcaattt tcatcagcta actctatgaa cattggtcgt ctggtgccac aaattgttta
    12721 ttatgtttat gcttacgctc aattggttaa gactggtgaa actgtagctg gtgaaaaggt
    12781 taacttcaca gtaccaacag gaaactttgg aaatatcttg gctgcctttt atgccaaaca
    12841 aattggtttg ccagttggta aattgatctg tgcttcaaat gacaacaatg ttttgacaga
    12901 cttctttaaa acacgtgtct atgacaaaaa acgtgagttt aaggtaacaa ccagcccatc
    12961 tatggatatc ttggtatctt caaacttgga gcgcttgatt ttccatcttt tgggaaataa
    13021 tgctgaaaag acagctgaac tcatgaatgc tttgaacatg caaggacaat ataagttgac
    13081 agactttgat gcagagattt tggacctctt tgcagctgaa tatgcgactg aggaagaaac
    13141 agcggcagaa atcaagcgtg tttatgagtt agattcttat attgaggatc cacatacggc
    13201 ggttgcctca gcagtttata gaaaatacca agcggttact gatgatgcga ctaagacagt
    13261 gattgcttca acagctagtc cctacaagtt cccagtagtt gcagtagaag ctgtaactgg
    13321 aaaagcaggt ttaacagact ttgaagcttt ggctcaatta catgaaatct caggcgttgc
    13381 agtgccacca gcagttgatg ggcttgagac agctcctgtt cgtcacaaga caacagtggc
    13441 agctgctgac atgcaagtag cggttgaggc ttatttagga ctttaagata gagggagtaa
    13501 actcggttgg gaaaccaact gagtttcttt tcatcaggag gagagattgt ttaagaaaaa
    13561 taaagacatt cttaatattg cattgccagc tatgggtgaa aactttttgc agatgctaat
    13621 gggaatggtg gacagttatt tggttgctca tttaggattg atagctattt caggggtttc
    13681 ggtagctggt aatattatca ccatttatca ggcgattttc atcgctctgg gagctgctat
    13741 ttccagtgtt atttcaaaaa gcatagggca gaaagaccag tcgaagttgg cctatcatgt
    13801 gactgaggcg ttgaagatta ccttactatt aagtttcctt ttaggatttt tgtccatctt
    13861 cgctgggaaa gagatgatag gacttttggg gacggagagg gatgtagctg agagtggtgg
    13921 actgtatcta tctttggtag gcggatcgat tgttctctta ggtttaatga ctagtctggg
    13981 agccttgatt cgtgcaacgc ataatccacg tctgcctctc tatgttagtt ttttatccaa
    14041 tgccttgaat attctttttt caagtctagc tatttttgtt ctggatatgg ggatagctgg
    14101 tgttgcttgg ggaacaattc tgtctcgttt ggttggtctt gtgattttgt ggtcacaatt
    14161 aaaactgcct tatgggaagc caacttttgg tttagataag gaactgttga ccttggcttt
    14221 accagcagct ggagagcgac ttatgatgag ggctggagat gtagtgatca ttgccttggt
    14281 cgtttctttt gggacggagg cagttgctgg gaatgcaatc ggagaagtct tgacccagtt
    14341 taactatatg cctgcctttg gtgtcgctac ggcaacggtc atgctgttgg cccgagcagt
    14401 tggagaggat gattggaaaa gagttgctag tttgagtaaa caaacctttt ggctttctct
    14461 gttcctcatg ttgcccctgt cctttagtat atatgtcttg ggtgtaccat taactcatct
    14521 ctatacgact gattctctag cggtggaggc tagtgttcta gtgacactgt tttcactact
    14581 tgggacccct atgacgacag gaacagtcat ctatacggca gtctggcagg gattaggaaa
    14641 tgcacgcctc cctttttatg cgacaagtat aggcatgtgg tgtatccgca ttgggacagg
    14701 atatctgatg gggattgtgc ttggttgggg cttgcctggt atttgggcag ggtctctctt
    14761 ggataatggt tttcgctggt tatttctacg ctatcgttac cagcgctata tgagcttgaa
    14821 aggataggaa atgcaaaaaa cagcttttat ttgggattta gacgggactt tattggactc
    14881 ttacgaagcg attttatcag ggattgagga gacttttgct cagttttcta ttccttatga
    14941 taaggagaag gtgagagagt ttatcttcaa gtattcggtg caaaatttgc ttgtgcgggt
    15001 ggcagaagat agaaatctgg atgttgaggt gctaaatcag gtgcgtgccc agagtctggc
    15061 tgagaagaat gctcaggtag ttttgatgcc aggtgcgcgt gaggtgctag cttgggcaga
    15121 cgaatcagga attcagcagt ttatatatac tcataagggg aacaacgctt ttaccattct
    15181 caaggacttg ggggtggaat cctattttac agagatttta accagtcaga gtggctttgt
    15241 gcggaagcca agtccagaag cggctaccta tctgctagat aagtatcagc tggatcctga
    15301 gaagacctat tatatagggg accggacttt agatgtggaa tttgccaaga atagcggtat
    15361 tcaaagcatc aactttttag aatcttcttt tgaaggcaat cacaggattc aagcactagc
    15421 agatatttcc cgtatttttg agactaagtg ataaaaagat tgtgtcagtt ttgtgacaga
    15481 gacctaacaa actatttcaa gtaatctagt ttgttacaag gaatagacag ttctgttaaa
    15541 taggcccgag agggcttttt ttctacattt tttgtgttat gatagacagg tactcatttg
    15601 aaaggaattt gaaagaatga agaaaagaat gttattagcg tcaacagtag ccttgtcatt
    15661 tgccccagta ttggcaactc aagcagaaga agttctttgg actgcacgta gtgttgagca
    15721 aatccaaaac gatttgacta aaacggacaa caaaacaagt tataccgtac agtatggtga
    15781 tactttgagc accattgcag aagccttggg tgtagatgtc acagtgcttg cgaatctgaa
    15841 caaaatcact aatatggact tgattttccc agaaactgtt ttgacaacga ctgtcaatga
    15901 agcagaagaa gtaacagaag ttgaaatcca aacacctcaa gcagactcta gtgaagaagt
    15961 gacaactgcg acagcagatt tgacaaccaa tcaagtgacc gttgatgatc aaactgttca
    16021 agttgcagat ctttctcaac caattgcaga agctccaaaa gaagtagcat caaattcaga
    16081 agttgcagag acagtgactg ctgcagaaga agtggcacca tctacgggca cttctgtccc
    16141 agaggagcaa acggccgaaa caactcgccc agttgaagaa gtagctcctc aggcaacgac
    16201 tctagctgag aagcaggaaa cacaagtgag ctctcaaacc gagtcagcag tggaagcaac
    16261 tacaatgcca gtagaagaaa aagcaaccga aacaactgca acaagttcag aagcaaaaga
    16321 agtagcatca tcaaatggag ctacagcagc agtttctact tatcaaccag aagagacgaa
    16381 aacaatttca acaacttacg aggctccagc tgcgcccgat tatgctggac tggcagtagc
    16441 gaaatctgaa aatgcaggtc ttcaaccaca aacagctgcc tttaaagaag aaattgctaa
    16501 cttgtttggc attacatcct ttagtggtta tcgtccagga gacagtggag atcacggaaa
    16561 aggtttggct atcgacttta tggtaccaga aagttcagaa ttaggggata agattgcgga
    16621 atatgctatt caaaacatgg ccagccgtgg cattagttac atcatctgga aacaacgttt
    16681 ctatgctcca ttcgatagca aatatgggcc agctaacact tggaacccaa tgccagaccg
    16741 tggtagtgtg acagaaaatc actatgacca cgttcacgtt tcaatgaatg gataaacccg
    16801 acttggtaac atcattttga cgaatgagat ctagctttcg tgataggaag cgattctcgt
    16861 tcgttttttc tttgtcatac tcttcgaaaa tctcttcaaa caacgtcagt tttatctgaa
    16921 acctcaaagc tgtgctttga gcaacctgcg actagcttcc tagtttgctt tttgattttc
    16981 attgagtatc aatttgaatg gaaaatggaa agttatcatc ttgtaatgag ttaagcaaca
    17041 ttcttgcaat ctattttata gtagattgaa actagaatag tacacaactg cttctaaaac
    17101 attgttagaa atcgatttga ctgtcctgat cgatttgtcc tgctcttatt tcatttcact
    17161 atactttata ttataattga ctggtcaaat attgataaat caataaaaag agaggggaag
    17221 aaatgctaga gattcaagat ttactgtatc aactccgctt gtctgagcaa gtgagtacgc
    17281 aattgtttga aaaagcttgg gattagtttg acacggtatc agattttact gtttttgctg
    17341 gagcattctc tttgtaacca aatggcggtt caggagcgtt tgaaaattga tcaggctgct
    17401 ttgacacgga atttcaagat tttggaaacg gaaggtttgg tggagcgtca tcgtaatcct
    17461 gaaaatcagc gggaagtatt ggtagaggct gcgaagtatg ccaaggagca gttagtggtg
    17521 aatccccctc tgcaacatat caaggttaag gaagagatgg aaagtatctt aacagagttt
    17581 gagagaacag aactcagccg tttattaaat aaattggttt tgggtattga aaatatagaa
    17641 atttaaggag aaatagatgt caattattac aattatttta acaacgatcg ttgcttggga
    17701 gcatttttac attttttatt tagaaagtat tgccacgcaa tcagatgcga ctagtcgtgt
    17761 atttaatatg gaaagggaag aattggctca tccgtcagta agtttattgt tcaaaaatca
    17821 agggatttat aaggctctgc taggagtctg tctcttgtat ggcatttatt tctcacagaa
    17881 tttagaaatt gtgactattt ttgtcttatt tgtgattggt gctgcgactt acggctcttt
    17941 aacagcggat aaaaaaatta ttttgaaaca aggtggatca gctattttgg ccttgattag
    18001 tattttactc tttaaataca cttgaaggtc gattctaatc tcgctaatcc tttttaatcc
    18061 agaataaggg aaatatgtta tacttgtttt taagaaaaaa gtttcattga attggttttg
    18121 aggagttaga aatgaaagta ttagtgacag gttttgagcc cttttgaggc cattaaaggt
    18181 ttaccagctg aaatccatgg tgctgaggtc cgttggctag aggtgccgac agtttttcac
    18241 aaatctgctc aagtattgga agaagagatg aatcgttatc aacctgactt tgtcctttgt
    18301 attgggcaag ctggtggaag aactagtttg acacctgaac gagtggccat taatcaagac
    18361 gatgcacgta cttctgataa cgaagataat caaccgattg accgtcccat tcgcccagat
    18421 ggtgcttcgg cctactttag tagtttgccg attaaagcga tggttcaagc tataaaaaaa
    18481 gagggcttac cggcctctgt ttccaatacg gcagggactt ttgtctgcag ccatttgatg
    18541 tatcaggctc tctatttggt agaaaagaaa tttccatatg ttaaggcagg ttttatgcat
    18601 attccttata tgatggaaca ggtggtgaac agaccgacta ctccagctat gagtttagtg
    18661 gatattcggc gagggataga agcagcaatc ggcgctatga tagaacatgg agatcaggaa
    18721 ctcaagttgg taggcggaga aactcattga tagaaaaaag cttgagggga aaaaccttca
    18781 agcttttgga cgttttcgag ccaatactgc tcggtaaaac ataattttag tgcattggat
    18841 ataaggtagg agtgaaaaac tagcaatgcc aaaggtaatc caattgagga agtaccaagg
    18901 aagaagctgt aaatctagga caaagcgctg gaacttgtag cccttcataa aggaacggct
    18961 agtttttagg attcgtcttg gtgggacctg tcctaggtct agactataac agagaagaaa
    19021 ttccacctgt gaataggcat aatactgtgg aatatagagg atatttccta caatgatcaa
    19081 gatgagactt gcaagaaagt agagtccaaa gaccatgagg aaacgctcgg tttcaactga
    19141 tgagagatct agatttggaa actcaggatg tagggtgacg aattttttgg ctaaaaagct
    19201 actataaaag aggaggtaaa tcccaagtaa attagggata ctccataaaa agagatagaa
    19261 acgtttgaga agtagggtca aaaaggtttg agaaaagcgc tcctcatcaa agagagctag
    19321 gctgtttttt acagatggct ccgttttaga atctttcatg agtgtcagtg ttgcatagac
    19381 ggaactggtc aaaagaatag tcccgataaa ggagactagt agaggaaaga ggtaggtttg
    19441 aagtatttgg ccaagtatgc tgaaaaatgg ctgttctaaa acagtcccgt ggatccgaga
    19501 taagggatta agaaaactag ataagatgac cagcatactg ggaaggatat agaggagaaa
    19561 gagacggggg gtgtcagcct gaaaatgttt tgactcctga cgaattgttt ttaaatcaat
    19621 ttttggatag ttcattctct tattatacca tagttcttat acatagttcg tgacagttcc
    19681 tacttttttt gataaaatca tacagtgtgt ccttgggcac actgtatgaa ctgggactgt
    19741 ctttcccagc ttcggaggta aaaaatgtca gattcaccaa tcaaatatcg tttgattaag
    19801 aaagaaaaac acacaggagc tcgtctagga gaaatcatca ctccccacgg tacctttccg
    19861 acacctatgt ttatgccagt tgggacacaa gccactgtca aaactcagtc acctgaagaa
    19921 ttgaaggaga tgggttcggg aattatccta tcaaacacct atcatctctg gcttcgccct
    19981 ggagatgaac tcattgcacg cgctggtggt ctccacaagt tcatgaattg ggaccagcct
    20041 atcttgacag atagtggtgg ttttcaggtt tattctttag cagatagccg taatatcaca
    20101 gaagaaggag taacctttaa aaatcatcta aatggttcta agatgctcct atccccagaa
    20161 aaagccatct ctattcagaa taatctgggt tcagacatca tgatgtcctt tgatgaatgt
    20221 cctcagtttt atcaacctta tgactacgtt aagaaatcga tcgagcgtac cagccgttgg
    20281 gctgagcgtg gtttgaaggc tcaccgtcgt ccacatgacc aaggtttgtt tggaattgtg
    20341 caaggtgcag gatttgaaga ccttcgccgc caatcagctc atgatcttgt cagcatggat
    20401 ttctcaggct actctatcgg tggtttggca gtgggagaaa cccatgaaga gatgaatgcg
    20461 gtcttggact ttacaactca actgctgcct gaaaataaac ctcgttatct gatgggtgtg
    20521 ggagcgccag atagcttgat cgatggggtc attcgtgggg tggatatgtt tgactgtgtc
    20581 ttaccgactc gaattgctcg taacgggact tgtatgacca gtcaaggacg tttggttgtg
    20641 aaaaatgccc agtttgctga ggactttacg ccactggatc ctgagtgtga ttgctacaca
    20701 tgtaataact atacacgcgc ttaccttcgt cacctgctca aggctgatga aacctttggt
    20761 atccgcttga ctagctacca caatctttac ttcttgctta acctgatgaa gcaagtgcga
    20821 caagccatca tggatgacaa tctcttggaa ttccgtaagt attttgtgga aaaatatggc
    20881 tataataagt caggacgtaa tttctaaaat ggaattgata taagctaaaa atcctaagtt
    20941 ttctcttagg atttttcttc tttttttgat agaataaagt gtacaatgaa aggaagaata
    21001 aactcgtatg cgcattaaat ggttttcctt ggttaggatt acaggtttac ttttggtact
    21061 cttgtatcac ttctttcaga cgatctttcc tggaggattt ttcggggtag atgtcttttt
    21121 cacattttca ggtttcctga ttacagctct actcattgaa gaattttcta aaaaccatga
    21181 gattgatttg ataggatttt ttagaagacg cttttatcgg attgtgccac ctgtggtttt
    21241 gatggtcttg gtgaccatgc cttttacttt cttggttcgc caagactatg ttgctggaat
    21301 tggtggccag attgcgagcg tcttaggctt tatgaccaac ttctatgaac tcctaacagg
    21361 tgggagttat gaatctcagt tcattcctca tttgtttgtt cataattgga gtttggcagt
    21421 tgaggttcac tactatattc tttggggatt ggcagtttgg ttcttatcca aacaagctaa
    21481 atcaaatggt cagttgaagg ggatggtctt tctcttatct gctgttgcct tcttgatcag
    21541 tttcttctcc atgtttattg gtagttttct agtgacctct tattcctctg tttatttctc
    21601 cagtttaact catgtctatc cattcttttt gggaagtatg ttagcaacta ttgtaggcgt
    21661 tcgtcagacg acttccctcg tcaagcagtt ggataaaatc tgggatttac gaaagacttt
    21721 ggtagttttt ggaggaggct ttggtttcct agttcttttg actttctttg tcaaattcac
    21781 ttatcttttt gcctatctta tcggcttctt acttgccagt cttgcagctc ttgccatgat
    21841 tctggcggcg cgtgtcttac atgaaaagac acatcatata caggagccga agattatcag
    21901 ctttttagcg gatactagct atgcggttta tcttttccat tggcctttct atatcatttt
    21961 ctcacagttg acatcaaatc ttcttgctgt attactgact ctgatttgtt cttatggctt
    22021 tgccagtctg tcattctatg tattggaacc ttggattgca ggcaagaaca cacctattgt
    22081 ccaaaccctt cgtcccctgc cttatattca cgcaattctt gcagcaggta caggaatctt
    22141 gaccatcatt gtctgcacgg tgaccttgtt ggcaccacaa gtgggagcgt ttgagacaga
    22201 cttgactgtc aatggcttga agcaagctgc aacaaatatt ggccagacca aggtgatggc
    22261 agaacgggca gatgcaaaca gtttgggaat tgctgatggc actatgttaa ttggtgactc
    22321 agtggcttta agggcaaata cagcactaca gacagctctt cctggagcac agattaacgc
    22381 gcaggtcagc gtaacaacca agaccgcaaa tgaaatcatg ctaaataata gccagaataa
    22441 atttttacct aagacggtgg tcattgcgac tggggtaaat aatcctgaga attacaagga
    22501 tgactgggac agtatcgtga aaaatcttcc taagggacac catatgattt tggtgactcc
    22561 ttatgaggga gataagacaa aagagaccta tgccatcgtt gagaaggctg ctgcctatat
    22621 gagagaattg gcagagaaga caccttacat tacgatagca gattggaatc aagttgcgaa
    22681 agagcatcca gaaatttggg caggaacaga ccaggttcat ttcgggagtg agagtagcac
    22741 tatcgaagca ggagcaaaat tgtatgcaga tacgattgcc acagctttgc agacagctca
    22801 agacaagccg gttaaatcaa aataacttgt attaaaaaag agaagagttg gagaaatcca
    22861 gctcttttaa aatatctcca aaaaataggt ctataccatt tacaaataaa aaagaaaggt
    22921 ttataatgta attgacataa taaattgtag aatcaatctt ttaaggaggt taacattatg
    22981 cctaactata ttaaagcgga tcagtttttc tacccacacg gagttcgtcg aggtggttac
    23041 ttggaacttg tggacggcaa gtttgggaaa catgtagagc agattcctga aggggctgag
    23101 gtgattgact atacaggtta tagcattgcc ccaggtcttg tggatactca tattcatgga
    23161 tatgcaggtg tagatgtgat ggacaacaac attgaaggta cattgcatac tatgagtgaa
    23221 ggacttctta gtaccggtgt taccagtttc ttacccacaa ctttaacagc cacttatgag
    23281 caattgcttg cagtcactga aaatcttgga aaccattata aagaagcaac aggtgctaag
    23341 attcgtggga tttattatga aggtccatat ttcacagaaa cttttaaggg ggcacaaaat
    23401 ccaacttata tgagagaccc gggtgttgag gagtttcatt cttggcaaaa agcggcaaat
    23461 ggcttgctta ataaaattgc ccttgcacca gaacgtgatg gggtggagga ctttgttcgt
    23521 acagttacgg gcgaaggtgt gacggttgct cttggacatt caaacgcgac ttttgatgaa
    23581 gccaaaaaag cagtcgatgc tggagcgagt gtttgggtgc atgcctacaa tggaatgcgt
    23641 gggttgactc accgtgaatt gggtatggtt ggagccatgt accaattgcc acatacctat
    23701 gcagagttga tctgtgatgg ccaccacgta gatccaaagg cttgcgaaat tcttatcaaa
    23761 caaaaaggaa cagaaaacat cgctcttatc acagactgta tgacagctgg gggattggaa
    23821 gacggagatt atatgttggg agaattccca gttgtcgttg caaatggaac tgcacgcctc
    23881 aaatcgacag gtaacttggc aggttctatc ctcaaactca aagatggttt gaagaatgtg
    23941 gtcgaatggg gaattgcgaa tccgcatgaa gcagtcatga tggccagctt caacccagct
    24001 aaatccgttc acatcgatga tgtctgtggc caaatccgtg aaggctacga cgctgacttc
    24061 atcgtattag ataaagattt ggaattggta gcaacctacc tagatggcgt aaaacgttat
    24121 caagcataag agagaaagca gaagttagag actaacttct gcttttttat gcagggtact
    24181 ttactggtaa ataaaaagtt aaaaaaatca caaaaaaagc ttgaagaaac aaagaaaaag
    24241 gcttacaatt gaactataaa tattacaaat aaaaaaacgg aggagtgctt tatgaaagcc
    24301 tatacttatg ttaaaccagg acttgcttct tttgttgatg tagacaaacc agttattcgc
    24361 aagccaacag atgctattgt gcgtattgta aaaaccacta tttgtggaac agacctccat
    24421 attatcaaag gggatgttcc tacttgccaa agtggtacca ttcttggcca cgaagggatt
    24481 gggattgttg aagaagttgg ggaaggagtt tccaacttca aaaaaggtga caaggtcttg
    24541 atttcttgcg tctgtgcctg tggtaaatgc tactactgta aaaaaggaat ttatgctcac
    24601 tgtgaagacg aagggggctg gattttcggt cacttgattg atggtatgca ggctgaatat
    24661 ctacgtgtcc ctcatgcaga taatactctt taccatactc cagaagactt gtcagatgaa
    24721 gctttggtta tgctgtcaga cattctgcct actggatatg aaattggtgt cttaaaaggg
    24781 aaagtagaac ctggttgcag cgtagccatt attggttcag gtccagttgg attggctgct
    24841 cttttaacag cccaattcta ttcaccagct aaattgatta tggtagacct agacgataac
    24901 cgcttggaaa ctgccctatc attcggtgcg actcataagg ttaattcttc agaccctgaa
    24961 aaagccatta aagaaattta tgatttgaca gatggtcgtg gtgtggatgt cgctatcgaa
    25021 gctgttggta ttcctgcaac atttgatttc tgtcaaaaga ttatcggtgt agacggaacg
    25081 gttgccaact gtggtgtgca tggtaaacca gttgaattcg atttagataa actttggatt
    25141 cgcaacatca atgtaacaac tggtttggta tctacaaata cgactccaca attgttgaaa
    25201 gcacttgaaa gtcataagat tgaaccagaa aaattggtaa ctcactattt caaactcagt
    25261 gaaattgaaa aagcctatga agtcttcagt aaggcagcag accaccatgc cattaaggtc
    25321 attatcgaaa acgatatctc agaagcctaa gtagtaaaaa tatttttgta cataagtaaa
    25381 tagaaattca gtcatccatc agatggctgg attttttatc aaaaaattaa gaaatgagca
    25441 tatttctttc cttgtctggc ggaattggtt ataatatacg gtacaaagga atgaatgaat
    25501 atgtatcgtg ttatagaaat gtacggagat tttgaaccgt ggtggttctt agaaggttgg
    25561 gaagaagata ttgtagcaag tagaaaattt gaccagtatt atgatgctct caaatactac
    25621 aaaacttgct ggtttagatt ggaacaagaa tcccctcttt ataaaagtag aagcgacttg
    25681 atgaccattt tttgggaccc ggaagaccaa cgctggtgtg atgaatgtga tgagtattta
    25741 caacaatacc attctttggc tcttttgcag gatgagcagg ttatcccaga cgaaaaacta
    25801 cgctcaggct atgaaaaaca aaccagtcag gaaaggaatc gttcttgccg tatgaaatta
    25861 aaatagagaa aagtaacttt tttggagttg ctttttttat ttttctaacg ctttgcgaat
    25921 agtataggtg aggaggtaag tatggttcaa gaaattgcac aagaaatcat tcgttcagct
    25981 cggaaaaaag ggacgcagga tatttatttt gtccctaagt tagacgccta tgagcttcat
    26041 atgagggtag gagacgagcg ctgtaaaatt ggtagctatg attttgaaaa gtttgcagcc
    26101 gttatcagtc actttaagtt tgtggcgggt atgaatgtgg gagaaaaaag acgtagtcaa
    26161 ctgggttcct gtgattatgc ctatgaccag aagatggcgt ctctacgttt atctactgta
    26221 ggcgattatc ggggacatga gagtttggtt atccgtttgt tgcacgatga ggagcaggac
    26281 ttgcattttt ggtttcagga tattgaagaa ttaggcaagc agtacaggca acggggactc
    26341 tatctttttg ctggcccggt tgggagtggt aagacgacct tgatgcatga attgtccaag
    26401 tcactcttta aaggacagca agttatgtcc atcgaagatc ctgtcgaaat caagcaggac
    26461 gacatgcttc agttgcagtt gaacgaagca atcggcctaa cctatgaaaa tctaatcaaa
    26521 ctttccttgc gtcatcgacc agatctcttg attatcggag aaattcgtga catcgagacg
    26581 gcgcgtgcag tggtcagagc tagtttgaca ggtgcgacag tcttttcaac cattcacgcc
    26641 aagagtatcc gaggtgttta tgagcgtctg ctggagttgg gtgtgagtga agaagaattg
    26701 gcagttgttc tgcaaggagt ctgctaccag agattaatcg ggggaggagg aatcgttgac
    26761 tttgcaaaca gagattatca agaacaccaa gcagccaagt ggaatgagca aattgaccag
    26821 cttcttaaag atggacatat cacaagtctt caggctgaga cggaaaaaat tagctacagc
    26881 taagcaaaaa aatatcatca ccctatttaa caatctcttt tctagcggtt ttcatctggt
    26941 ggagactatc tcctttttag ataggagttc cttgttggac aagcagtgtg tgacccagat
    27001 gcgtacaggc ttgtctcagg ggaaatcatt ctcagaaatg atggaaagtt tgggatgttc
    27061 aagtaccatt gtcactcagt tatctctagc tgaagttcat ggcaatcttc acctgagttt
    27121 gggaaagata gaagaatatc tagacaatct ggccaaggtc aagaaaaagt taattgaagt
    27181 agcgacctat cctttgattt tgctgggttt tcttctctta attatgctgg ggctacggaa
    27241 ttacctgctc ccacaactgg atagtagcaa tattgccacc cgaattatcg gtaatctgcc
    27301 acaaattttt ctaggcatgg tagggcttgt ttccgtgctt gcccttttag cactaacttt
    27361 ttataaaaga agttctaaga tgagtgtctt ttctatctta gcacgccttc cctttattgg
    27421 aatctttgtg cagacctact tgacagccta ttatgcacgt gaatggggga atatgatttc
    27481 acagggaatg gagctgacgc agatttttca aatgatgcag gaacaaggtt cccagctctt
    27541 taaagaaatc ggtcaagatc tggctcaaac cctgaaaaat ggccgtgaat tttctcagac
    27601 gataggaacc tatcctttct ttaggaagga attgagtctc atcatagagt atggggaagt
    27661 taagtccaag ctgggtagtg agttggaaat ctatgctgaa aaaacttggg aagccttttt
    27721 tacccgagtc aaccgtacca tgaatttggt gcagccactg gtttttatct ttgtggcact
    27781 gattatcgtt ttactttatg cggcaatgct catgcccatg tatcaaaata tggaggtaaa
    27841 tttttaaaat gaaaaaaatg atgacattct tgaaaaaagc taaggttaaa gcttttacat
    27901 tgattgagat gttggtggtc ttgctgatta tcagcgtgct tttcttgctc tttgtaccta
    27961 atctgaccaa gcaaaaagaa gcagtcaatg acaaaggaaa agcagctgtt gttaaggtgg
    28021 tggaaagcca ggcagaactt tatagcttag aaaagaatga agatgctagc ctaagaaagt
    28081 tacaagcaga tgggcgcatc acggaagaac aggttaaagc ttataatgaa tactatacta
    28141 aaaatggagg ggcaaatcgt aaagtcaatg attaaggcct ttaccatgct ggaaagtctc
    28201 ttggttttgg gacttgtgag tatccttgcc ttgggcttat ccggctctgt ccagtccact
    28261 tttgcagcag tagaggagca gattttcttt atggagtttg aagaactcta tcgggaaacc
    28321 caaaaacgca gtgtagccag tcagcaaaag actagtctaa atttagatgg gcagacgctt
    28381 agcaatggca gtcaaaagtt gacagttcct aaaggaattc aggcaccatc aggccaaagt
    28441 attacatttg accgagctgg gggcaattcg tccctggcta aggttgaatt tcagaccagt
    28501 aaaggagcga ttcgctatca attatatcta ggaaatggaa aaattaaacg cattaaggaa
    28561 acaaaaaatt agggcagtga ttttactgga agcagtagtc gctctagcta tctttgccag
    28621 cattgcgacc ctccttttgg gacaaattca aaaaaatagg caagaggaag caaaaatctt
    28681 gcaaaaggaa gaagtcttga gggtagctaa gatggccttg cagacaggtc aaaatcaggt
    28741 aaacataaac ggagttgaga ttcaggtgtt ttctagcgaa aagggattgg aggtctacca
    28801 tggttcagaa cagttgttgg caatcaaaga gccataaggt caaggctttt accttgttag
    28861 aatccctgct tgccctgatt gtcatcagtg ggggcttact cctttttcaa gctatgagtc
    28921 agctcctcat ttcagaagtt cgctaccagc aacaaagcga gcaaaaggag tggctcttgt
    28981 ttgtggacca acttgaggca gaattagacc gttcgcagtt cgaaaaagta gaaggcaatc
    29041 gcctatacat gaagcaagat ggcaaggaca tcgccatcgg taagtcaaag tcagacgatt
    29101 ttcgtaaaac cgatgctagt ggacgggggt atcagcctat ggtttatggc ctcaaatcag
    29161 ctcagattac agaggacaat caactggttc attttcgttt ccagtttcaa aaaggcttag
    29221 aaagggagtt catctatcgt gtggaaaaag aagaaagtta aggcaggtgt tctcctctac
    29281 gcagtcacca tagcagccat ctttagtctt ttgttgcaat tttatttgaa ccgacaaatc
    29341 gcccactatc aagactatgc tttaaataaa gaaaaattgg ttgcttttgc catggctaaa
    29401 cgaaccaagg ataaagccga gcaagaaagt ggggaacagg tttttaatct aggtcaggta
    29461 agctatcaaa acaagaaaac aagcttggtg acgactgttc gtacgtctaa gagccaatat
    29521 gagtttctgt ttccttcagt caaaatcaaa gaagagaaaa gagataaaaa ggaagaggta
    29581 gcgaccgatt caagcgaaaa agcggagaaa aaaaatcaga agagaagcct gaaaagaaag
    29641 agaattccta gtcaattcaa ctataatgcg ttgaatccag aatagtccac tgtagtttct
    29701 agaaaattgc tggaaatgga tgttaagctc caattcattt gtttatatct tatttcagtt
    29761 tactatactt tgtgctaaat taaagatatg aaacatgatt ttaaccacaa agcagaaact
    29821 ttcgattccc ctaaaaatat cttcctcgca aacttggtat gtcaagcagc cgagaaacag
    29881 attgatcttc tatcagacaa agaaatttta gatttcggtg gtgacacggg tctattagcc
    29941 ttgcccctag cccctagcca agcaggctaa gtcagtcact cttgtagaca tttctgagaa
    30001 aatgttggag taagctcgtt tgaaagcgga gcagcaagca atcaagaata tccagttttt
    30061 ggagcaagat ttaccgaaaa atcccttgga gaaagagttt gattgccttg ctgttagtcg
    30121 gcttcttcat catatgcctg atttggatgc ggatctctca ctgtttcatc aacatttgaa
    30181 ggaagatagg aaactcatca ttgctgattt taccaagaca gaagctaatc atcatggatt
    30241 tgatttagct gaactggaaa acaagctaat tgagcatggt ttttcatctg tgcatagtca
    30301 gattctctat agcgctgaag acctgtttca agggaatcac tcagaattct ttttaacagt
    30361 atcccaaaaa tcactcgcct agtcagggag tgatttttct ataaggatgg aaaaaagaag
    30421 ggaaatttga taagatagga atatggattt tgaaaaaatt gaacaagctt atatctattt
    30481 actagagaat gtccaagtca tccaaagtga tttggcgacc aacttttatg acgccttggt
    30541 ggagcaaaat agcatctatc tggatggtga aactgagcta aaccaggtca aagacaacaa
    30601 tcaggccctt aagcgtttag cactacgcaa agaagaatgg ctcaagacct accagtttct
    30661 cttgatgaag gctgggcaaa cagaaccctt gcaggccaat caccagttta cgccagatgc
    30721 tattgcctta cttttggtat ttattgtgga agagttgttt acagaggagg aaattactat
    30781 cctcgaaatg ggttctggga tgggaattct aggcgctact ttcttgacct cgcttgataa
    30841 aaaggtggat tacttgggaa tggaagtgga tgatttgctg attgatctgg cagctagcat
    30901 ggcagatgta attggtttgc aggctggctt tgtccaagga gatgccgttc gcccacaaat
    30961 gctcaaagaa agcgatgtgg tcatcagtga cttgcctgtc ggctattatc ctgatgatgc
    31021 cgttgcgtcg cgtcatcaag ttgcttctag ccaagaacat acttacgccc atcacttgct
    31081 catggaacaa gggtttaagt accttaagtc agatggatat gctatttttc tagctccgag
    31141 tgatttgttg accagtcctc aaagtgattt gttgaaagtc tggttgaaag aggaggcaag
    31201 tctggttgct atgattagtt tacctgaaaa tctctttgct aatgctaaac aatctaagac
    31261 tatttttatc ctacagaaga aaagtgaaat agcagtggag ccttttgttt atccacttgc
    31321 tagcttgcaa gatgcaagtg ttttaatgaa atttaaagaa aattttcaaa aatggactca
    31381 aggtactgaa atataaaata gattttgtta taatagttga aaacgcttaa aaaggggtat
    31441 catgttatga caaaaacaat tgcaatcaat gcaggaagtt caagtttgaa atggcaatta
    31501 tacttaatgc cagaggaaaa agtgttagcc aaaggtttga ttgaacgtat cggtttgaaa
    31561 gattcaattt caactgtaaa atttgacggc cgttctgaac aacaaatttt ggatattgaa
    31621 aatcatacac aagccgttaa aattttattg gatgacttga ttcgtttcga tattatcaag
    31681 gcttatgacg agattacagg tgttggacat cgtgttgttg ctggtggaga atatttcaaa
    31741 gaatcaacag ttgttgaggg agatgtttta gaaaaagttg aagagttgag tttgttggct
    31801 cctctacaca acccggccaa tgcagcaggt gttcgtgcct tcaaggaatt gttgccagac
    31861 attaccagtg tagttgtttt tgatacttcc ttccacacaa gtatgccaga gaaagcttat
    31921 cgctaccctc taccaacaaa atattacaca gaaaacaagg ttcgtaaata cggtgctcat
    31981 ggtacaagtc accagtttgt agcaggagaa gctgcaaaac tcttgggacg tccattagaa
    32041 gacttgaagt taattacctg tcatattggt aacggaggct caattacagc tgtgaaagcc
    32101 ggcaaatctg tagacacttc tatggggttc actcctcttg gtggtattat gatgggaacg
    32161 cgtacagggg atattgatcc agctatcatt ccttatttaa tgcaatatac agaggatttt
    32221 aacacaccag aagatatcag tcgtgttctt aaccgtgaat caggtctttt gggagtttct
    32281 gctaattcta gcgatatgcg cgatatagaa gcagctgtag cagaagggaa tcacgaggct
    32341 agcttggctt atgaaatgta tgttgaccgt atccaaaaac atatcggtca gtaccttgca
    32401 gtgctaaatg gagcagatgt cattgttttc acagcaggtg tcggtgaaaa tgcagagagt
    32461 ttccgtcgtg atgtaatctc agggatttcg tggtttggtt gtgatgttga tgatgaaaag
    32521 aatgtctttg gcgttacagg agacatctca acagaggcag ctaaaatccg tgtcttggtt
    32581 attccaacag atgaagaatt agtcattgcc cgtgacgttg aacgcttgaa aaaataagtg
    32641 aaactaaaaa aatattcaat acaaggagtt gggaaagtta tttttccagc ttctttttct
    32701 gatgaaattg tccaaaacct tgctatgatt ggcttttttg aaaaatatgg tataatagta
    32761 gtaatttaat agatggagtt gagttttgaa gaaaaacttt cgtgtaaaaa gagagaaaga
    32821 ttttaaggcg attttcaagg aggggacaag ttttgctaat cgcaaatttg tggtctacca
    32881 attagaaaac cagaaaaacc attttcgagt aggtctatca gttagcaaaa aactggggaa
    32941 tgccgtcact agaaatcaaa ttaagcgacg gattcggcat attatccaga atgcaaaagg
    33001 gagtctggta gaagatgtcg actttgttgt cattgctcga aaaggagtcg aaaccttggg
    33061 atacgcagag atggagaaaa atctactcca tgtattaaaa ttatcaaaga tttaccggga
    33121 aggaaatggg agtgaaaaag aaactaaagt tgactagttt gctaggactg tctctgttaa
    33181 tcatgacagc ctgtgcgact aatggggtaa ctagcgatat tacagccgaa tcggctgatt
    33241 tttggagtaa attggtttac ttctttgcgg aaatcattcg ctttttatcg tttgatatta
    33301 gtatcggagt ggggattatt ctctttacgg tcttgattcg tacagtcctc ttgccagtct
    33361 ttcaggtgca aatggtggct tctaggaaaa tgcaggaagc tcagccacgc attaaggcgc
    33421 ttcgagaaca atatccaggt cgagatatgg aaagcagaac caaactagag caggaaatgc
    33481 gtaaagtatt taaagaaatg ggtgtcagac agtcagactc tctttggccg attttgattc
    33541 agatgccggt tattttggcc ctgttccaag ccctatcaag agttgacttt ttaaagacag
    33601 gtcatttctt atggattaac cttggtagtg tggatacaac ccttgttctt ccgattttag
    33661 cagcagtatt caccttttta agtacttggt tgtccaacaa agctttgtct gagcgaaatg
    33721 gcgctacgac tgcgatgatg tatgggattc cagtcttgat ttttatcttt gcagtttatg
    33781 cgccaggtgg agtcgcccta tactggacag tgtctaatgc ttatcaagtc ttgcaaacct
    33841 atttcttgaa taatccattc aagattatcg cagagcgcga ggccgtagta caggcacaaa
    33901 aagatttgga aaatagaaaa agaaaagcca agaaaaaggc tcagaaaacg aaataaataa
    33961 ggaggaatct ggtaatggta gtatttacag gttcaactgt tgaagaagca atccagaaag
    34021 gattgaaaga attagatatt ccaagaatga aggctcatat caaagtcatt tctagggaga
    34081 aaaaaggctt tcttggtcta tttggtaaaa aaccagccca agtggatatt gaagcgatta
    34141 gtgaaacgac tgttgtcaaa gcaaatcaac aggtagtaaa aggcgttccg aaaaaaatca
    34201 atgatttgaa cgagcctgtg aagacggtta gtgaagaaac cgttgacctt ggtcatgtag
    34261 ttgatgctat taaaaaaata gaggaagaag gtcaaggtat ttctgatgaa gtcaaggctg
    34321 aaatcttaaa acatgaaaga catgccagca ctatcttaga agaaactggt cacattgaga
    34381 ttttaaatga acttcaaatc gaggaagcga tgagggaaga agcaggcgct gatgaccttg
    34441 aaactgagca agaccaagct gaaagtcaag aactagaaga cttgggcttg aaagttgaaa
    34501 cgaactttga tattgaacaa gtagctacgg aagtaatggc ttatgttcaa acgattattg
    34561 atgacatgga tgttgaggct acactttcaa atgattataa ccgtcgtagc atcaatttgc
    34621 aaattgatac taacgaacca ggtcgtatta tcggctacca tggtaaagtc ttgaaggcct
    34681 tgcaactgtt ggctcaaaat tatctttaca actgctattc aagaaccttc tatatcacta
    34741 ttaatgtcaa tgattatgtt gaacaccgtg cagaagtctt gcagacctat gcgcaaaaat
    34801 tggcgattcg tgttttagaa gaaggacgta gtcatcaaac agatccaatg tcgaatagtg
    34861 aacgcaagat tatccaccgt attatttcac gtatggatgg cgtgaccagt tactctgaag
    34921 gtgatgagcc aaatcgctat gtcgttgtag atacagaata agtaaaatca gggttgacct
    34981 gattttttgc tagctagagg aggttaaact gatgttgaat aagataagag actatttaga
    35041 ctttgctggt ttgcagtacc gtaatcctga taaagcggga gcagagcgag agaagatgct
    35101 ggcattccgc cacaaaggac aagaggcccg aaaggctttt acagaactgg ccaaagcctt
    35161 tcaagcaagc catccagaat ggcaactcca acagactagt cagtggatga atcaggccca
    35221 gcgtttgaga ccacattttt gggtttatct acagagagac ggacaagtga cagaacctat
    35281 gatggcctta cgtttgtatg ggacatctac tgactttgga atttctttgg aagtcagttt
    35341 catcgaacgt aagaaggatg agcaaacact gggcaagcag gccaaagttt tagacattcc
    35401 aaccgttaaa gggatttatt atctaaccta ctctaatggt caaagtcaac ggtgggaggc
    35461 gaatgaagaa aagcgtcgta ctttacgcga gaaggtgaga agtcaagaag ttcgaaaagt
    35521 tttagtgaag gtagatgttc ctatgacaga aaattcgtct gaagaagaaa tcgtagaagg
    35581 cttattgaag tcttattcta aaattcttcc ctattatcta gctacgagaa aataagataa
    35641 tttgtaaaac atcataaatc atacagtcca agagtgaaca gtccgctgtg taattcttgg
    35701 tctttttgtt tgcgctttcg cattatataa taaacttaca aaaacaattc aaaaggagaa
    35761 caattatgga agtcgtttca agtgttctaa attggttttc tagcaatatt ttgcagaatc
    35821 ccgcattttt cgtaggttta ttggtgttga taggatatgc acttttgaaa aaacctgccc
    35881 atgacgtttt ttcagggttt gttaaagcaa cagtagggta tatgttgctt aacgtgggtg
    35941 ctggtggttt ggttacaacc tttcgtccaa tcttagcagc tcttaactac aaattccaaa
    36001 ttggtgcagc ggttatcgac ccttactttg gacttgctgc agcaaacaac aaaattgcag
    36061 cagagtttcc agattttgtt ggaactgcaa ctacagctct attgattggt tttggaataa
    36121 atatcttgct cgtagctctt cgaaagatta cgaaggtaag aaccctcttt attactggtc
    36181 acatcatggt acaacaagct gcaacagtat ctcttatggt tctattctta gtaccacaat
    36241 tgcgcaatgc ttacggtaca gcagcgattg gtatcatctg tggactttac tgggcagtta
    36301 gttcaaatat gactgttgag gcaactcaac gcttgactgg tggtggcgga tttgcgattg
    36361 gtcaccaaca gcaatttgca atctggtttg tagataaagt agcaggacgc tttggtaaga
    36421 aagaagaaag tttagacaat cttaaattac ctaagttcct ctcaatcttc cacgatacag
    36481 ttgttgcatc tgctaccttg atgctcgtat tcttcggagc cattctttta atcttgggtc
    36541 cagacattat gtctaataaa gaagtcatca cttcaggaac tctattcaat cctgctaaac
    36601 aagatttctt tatgtacatt atccaaacag cctttacctt ctcagtttac ttgttcgttt
    36661 tgatgcaagg tgtccgaatg ttcgtatctg agttgacaaa cgccttccaa ggtatttcaa
    36721 acaaattgtt gccaggttca ttcccagcgg ttgacgttgc agcttcttat ggatttggtt
    36781 ctccaaatgc tgtcttgtca ggatttacct ttggtttgat tggtcaattg attacaattg
    36841 tcttgctcat cgtctttaaa aatccgattc ttattattac aggatttgta ccagtgttct
    36901 ttgacaatgc agccattgcg gtctacgctg ataaacgcgg cggatggaaa gcggctgtta
    36961 tcctttcctt tatatcaggt gtccttcaag ttgctctagg agctctttgt gtggcccttc
    37021 tcgatttggc atcttatggt ggctaccatg gaaatatcga ctttgaattc ccatggcttg
    37081 gatttggata tatcttcaaa taccttggta ttgttggtta tgtacttgtg tgtctcttct
    37141 tgcttgttat tcctcaactt caatttgcca aagcaaaaga taaagagaaa tattacaacg
    37201 gtgaagttca agaagaagct tagtatctag aaaaggagaa ataaaatggt taaagtatta
    37261 gcagcgtgcg gaaatggaat gggttcatca atggttatca agatgaaggt tgaaaatgct
    37321 ctccgtaagc ttaatcaaac agattttaca gtcaattcat gcagtgtcgg tgaagctaaa
    37381 ggtttagcag taggatatga catcgtaatc gcttctcttc atttgattca agaattggaa
    37441 gggcgaacta atgggaagtt aattgggctt gataacttga tggatgataa agaaatcacc
    37501 gaaaaactca gtcaagcact acagtaaaag gttggagggg gctggacaga aactgagagt
    37561 tatcgtttct gtccttctcc ctctttaaat aaaggaggca gatatgaatt taaaacaagc
    37621 tttaattgac aatgactcga tccgactagg tttagaggct aacaattgga aagaagcagt
    37681 caaggtagca gtagatccct taattgaaag tggggcaatt ttgccagagt attacgatgc
    37741 tatcattgaa tcgactgaag agtatgggcc ttactatatc ttgatgccag gtatggctat
    37801 gccccacgct agacctgaag ctggtgtgca aagtgatgcc ttttcattga ttaccttaca
    37861 aaatcctgtt gtattttcag atgggaaaga ggtatctgtt ttgttggcac tagcagcaac
    37921 aagttcaaaa attcacacaa gtgtagccat tccacaaatt attgccctgt ttgaattaga
    37981 agattctatt gcacgtttac aggcttgcca gactaaagaa gatgtcttgg ctatgattga
    38041 agaatctaag gatagccctt atctcgaagg attggatttg gaaagttaga aagaggaata
    38101 aagaaatgac aaaaagaata cctaatttac aagttgcatt agaccattca gacttgcaag
    38161 gagcgattaa agcagctgtt tctgttggtc aggaagtaga tattatcgaa gctggaactg
    38221 tttgcttgct tcaagttgga agtgaactgg ctgaagtctt gcgtagcctt ttcccagata
    38281 agattattgt ggcagacaca aaatgtgctg atgctggtgg aacagttgct aaaaataatg
    38341 cggttcgtgg agcagactgg atgacttgta tctgttgtgc aaccatccct actatggaag
    38401 cagctctaaa ggctatcaag actgaacgag gagaacgagg cgaaatccag atcgagcttt
    38461 atggcgattg gacttttgaa caagctcagc tttggctaga tgcaggtatc tcacaagcta
    38521 tttatcacca atctcgtgat gctcttcttg ctggtgaaac ttggggtgaa aaagacctta
    38581 ataaggttaa aaaactcatt gatatgggct tccgtgtatc tgtaacaggt ggtctagatg
    38641 tagatactct caaactcttt gaaggtgttg atatctttac ctttatcgca ggtcgtggaa
    38701 ttacagaggc tgcggatcca gcaggagcag cgcgtgcctt caaggatgaa atcaaacgaa
    38761 tttgggggta aatcatggta cgtccaattg gaatttatga aaaggcaacc ccaacacact
    38821 ttacttggct agaacgttta aattttgcca aggagttagg ctttgatttt atcgagatgt
    38881 ctattgacga acgtgacgag cgtttagcaa gacttgactg gagtaaggaa gaacgcttgg
    38941 aagttgtcaa agaaatctat gaaactggtg ttcgtattcc ttctatctgt ttttcaggcc
    39001 atcgtcgcta cccattggga tcaaaagatt cagttctaga ggaaaaatct ctagaactca
    39061 tgaaaaaatg tatcgaatta gctcaagact tgggagttcg tacgattcaa ttagctggtt
    39121 acgatgttta ctatgaggaa aagtcacccc agacacgcca acgttttatc aaaaatttga
    39181 gaaaagcctg tgactgggct gaagaagctc aggtggtact tgctattgaa attatggatg
    39241 atcctttcat cagtagcatc gaaaaatatt tggctataga aaaagagatt gactctccct
    39301 tcctctttgt atatccagat attggtaatg tgtctgcatg gcataatgat atctatagtg
    39361 agttttatct tggtcatcat gccatcgcag ctctccatct caaggatact tatgcagtga
    39421 cagaaagttc aaagggccag ttccgagatg tacctttcgg gcaaggttgt gtcaaatggg
    39481 aagaagcttt cgatatttta aaggaaacca attataatgg acctttccta atcgaaatgt
    39541 ggtctgaaaa ttgtgaaaca gtagaagaaa cacgcgcagc cattcaagag gcgcaagctt
    39601 ttctctatcc actcattaag aaagcaggtt tgatgtaaga tgaatcaagt aatcaatgct
    39661 atgcgtaaac gagtctgtga tgccaatcaa tcattgccaa aacatggact tgtcaaattt
    39721 acctggggga atgtatctga agtcaatcgc gaactcggtg tcattgttat caaaccatca
    39781 ggcgtggatt atgacgaatt gacacctgaa aacatggtag tgactgatct agatggtaag
    39841 atcctagaag gggatttaag accatcttcc gacctcccaa ctcatgtgca attatataag
    39901 gcttggtcag aaattggtag tgtggttcac acccattcga cagaagctgt tgcttgggct
    39961 caggcaggtc gtgatattcc tttctacgga acaacccatg cagattattt ctacggttca
    40021 attccttgcg cccgtagttt gaccaaggac gaagtagaag tggcctatga aaaagatact
    40081 ggcctggtta tcgtagaaga gtttgaacat cgcggactta acccggttga agtaccagga
    40141 attgttgtac gcaatcacgg tccattcacc tggggcaaaa atccagagaa tgctgtttat
    40201 cactctgtcg tactagagga agtatcaaag atgaatcgct ttacagaaca aatcaatcca
    40261 agagttggac ctgctcccca gtacatacta gaaaaacact accaacgtaa acatggacca
    40321 aatgcttatt atggtcaaaa gtaagaacga tgaaggagga gaaaaagata aatttagctc
    40381 ctctttttac atttgatttt tattgagagt aaagttggag ttgaagtaat tttaaaagat
    40441 tttttagaaa tagcgcttga tatatatatg gtaaaataaa aagaattgct gtgatatcaa
    40501 tagatttggg ggatttttta atatggtact ggataaggca agttgtgatt tgcttcaata
    40561 tttgatggat caagaaacgt ccaaaacgat tatggcgatt tcgaaagatt tgaaagagtc
    40621 aagaaggaaa atttattatc acattgacaa aatcaatgct gctctgggtg acgaggcgct
    40681 tcacatcatt agtattccac gaattggtat tcacttaacg gaagagcaga gagatgcttg
    40741 ttgtaaacta ttatcggaag tagattcgta cgattatatc atgagtgcgc atgaacgtat
    40801 gatgataatg ttactatgga taggtatttc taaagaacgt attacgattg aaaaattgat
    40861 agagttaaca gaggtatcta ggaatactgt tctcaatgat ttgaatagta ttcgttatca
    40921 actaactttg gaacaatatc aggtgatctt gcaagtgagc aagtcacagg gataccacct
    40981 tcatgcccac cctcttaata aaattcagta tcttcaatcg cttctatatc atatttttat
    41041 ggaagaaaat gccacttttg tatctatttt agaagataag atgaaagaga ggttagatga
    41101 tgagtgtttg ctttctgttg aaatgaacca attttttaag gaacaggttc ctttagttga
    41161 acaagattta gggaagaaaa taaatcatca tgaaataact tttatgttgc aggttctacc
    41221 ttatttgctg ttaagctgtc ataatgttga acagtatcaa gaaagacatc aggatataga
    41281 gaaagaattt tctttgataa gaaaaagaat agagtatcag gtgtctaaga aattaggaga
    41341 acggttgttt caaaagtttg aaatttcttt gtcaggactt gaagtttctc ttgtagctgt
    41401 tctcctcctc tcctatcgta aagatttgga tattcatgca gaaagtgatg attttcggca
    41461 attaaaactt gctttagaag aatttatctg gtattttgaa tcacaaatcc gaatggagat
    41521 tgagaacaag gatgatttgt tacgaaattt gatgatccac tgtaaagcct tgttatttag
    41581 aaagacttac ggtatttttt ctaaaaatcc tctaacaaaa caaattcgat ccaagtatgg
    41641 agaattattt ttagtcacta gaaaatctgc ggaaatttta gaaggagcat ggtttattcg
    41701 gctaacagac gatgatattg cctatttgac gattcatatt ggaggatttt taaagtatac
    41761 accatcgtct caaaaaaata tgaaaaaagt ttatctcgtt tgtgatgaag gtgttgcggt
    41821 ttcgagactt ttgctgaaac aatgcaaact ttattttcca aatgagcaaa ttgacactgt
    41881 atttacaaca gaacaattta agagtgtgga agatattgca caagttgatg tagtgattac
    41941 tactaatgat gatttggata gcagatttcc gattttaagg gttaatccta tccttgaagc
    42001 agaagatatt ttgaaaatgc tagactatct taaacacaat atatttcgta ataagagcaa
    42061 aagtttcagt gaaaatcttt ctagtcttat ttcgtcttat attgtagaca gcaagttggc
    42121 tagtaagttc caagaagagg ttcaaacact tataaatcaa gaaatagtag ttcaagcttt
    42181 tttggaagat atttgaagga cagtccaatg atgaacacaa acctgtgttt ttcttggtct
    42241 tttttagtgt tttgaagggt ggtatactaa tctcaaagat aacaattata tccaaaggag
    42301 gcaacatatg ccaaacgtca aagaaattac aagagagtca tggattttag ccactttccc
    42361 agagtgggga acatggttga acgaagaaat cgaagaagaa gtcgtacctg aaggcaactt
    42421 tgccatgtgg tggctaggca actgtggtac ttggattaag acaccagctg gtgctaacgt
    42481 tgtcatggac ctttggtcaa accgtggaaa atcaaccaaa aaagtgaaag atatggttcg
    42541 tgggcaccaa atggcaaata tggcaggtgt tcgtaaattg caaccaaact tgcgtgttca
    42601 gccaatggtt atcgatccat ttgctatcaa cgaactagac tattacttag tttcacactt
    42661 ccacagtgat catatcgacc catacacagc tgcagcaatt ctcaacaatc ctaagttaga
    42721 gcatgttaag tttatcggtc cttaccactg tggacgaatc tgggaaggat ggggggttcc
    42781 aaaagaacgt atcatcgttg ttaaaccagg tgacactatc gaattaaaag atatgaagat
    42841 tcatgcagta gaatcatttg accgtacttg cttggtaact ctcccagtga acggtgctga
    42901 tgagacaggc ggtgaacttg ctggcttggc tgttacagat gaagaaatgg ctcaaaaggc
    42961 tgttaactat atctttgaaa caccaggtgg aaccatctat catggtgcag attctcactt
    43021 ctcaaactat tttgcaaaac atggtaaaga ctttaaaatt gatgttgctt tgaataacta
    43081 tggtgaaaat ccggtaggta tccaagacaa aatgacatct atcgaccttc ttcgtatggc
    43141 agaaaatctg cgtaccaaag tcattatccc agttcactat gatatctggt ctaacttcat
    43201 ggcttctact aatgagattc tagaactttg gaaaatgcga aaagatcgct tgcaatacga
    43261 tttccatcca tttatctggg aagttggcgg taagtacact tatcctcaag atcaacactt
    43321 agtagaatac catcatccac gtggttttga tgattgtttt gaacaagact ctaacattca
    43381 atttaaagct ttgctataat ataaaaatat tctttggagg ttatccgtat gttgcatgat
    43441 acggataatt ttcatataat agtaaaatag aatgtgtgat tcaataatca cctcaaatag
    43501 aaaggaaatt ctatgtcaaa tctatctgtt aatgcaattc gttttctagg tattgacgcc
    43561 attaataaag ccaactcagg tcatccaggt gtggttatgg gagcggctcc gatggcttac
    43621 agcctcttta caaaacaact tcatatcaat ccagctcaac caaactggat taaccgcgac
    43681 cgctttattc tttcagcagg tcatggttca atgctccttt atgctcttct tcacctttct
    43741 ggttttgaag atgtcagcat ggatgagatt aagagtttcc gtcaatgggg ttcaaaaaca
    43801 ccaggtcacc cagaatttgg tcatacggca gggattgatg ctacgacagg tcctctaggg
    43861 caagggattt caactgctac tggttttgcc caagcagaac gtttcttggc agccaaatat
    43921 aaccgtgaag gctacaatat ctttgaccac tatacttacg ttatctgtgg agacggagac
    43981 ttgatggaag gtgtctcaag cgaggcagct tcatacgcag gtttgcaaaa acttgataag
    44041 ttggttgttc tttatgattc aaatgatatc aacttggatg gtgagacaaa ggattccttt
    44101 acagaaagtg ttcgtgaccg ttacaatgcc tacggttggc atactgcctt ggttgaaaat
    44161 ggaacagact tggaagccat ccatgctgct atcgaaacag caaaagcttc aggcaagcca
    44221 tctttgattg aagtgaagac ggttattgga tacggttctc caaacaaaca aggaactaat
    44281 gctgtacacg gcgcccctct tggagcagat gaaactgcat caactcgtca agccctcggt
    44341 tgggactacg aaccatttga aattccagaa caagtatatg ctgatttcaa agaacatgtt
    44401 gcagaccgtg gcgcatcagc ttatcaagct tggactaaat tagttgcaga ttataaagaa
    44461 gctcatccag aactggctgc agaagtagaa gccatcatcg acggacgtga tccagtcgaa
    44521 gtgactccag cagacttccc agctttagaa aatggttttt ctcaagcaac tcgtaattca
    44581 agtcaagatg ccttgaatgt tgtggcagct aaattaccaa ccttcctagg tggatcagct
    44641 gaccttgctc actcaaacat gacttatatc aagacggatg gacttcaaga cgataccaat
    44701 cgcttgaatc gtaacattca gtttggtgtt cgtgaatttg caatgggaac aatcttgaac
    44761 gggatggccc ttcatggtgg acttcgtgta tacggtggaa ctttcttcgt cttctctgac
    44821 tatgtgaagg cagctgtccg cttgtcagcc ttacaaggac ttcctgtgac ttatgtcttt
    44881 acccatgatt caatcgcagt tggggaagat ggtccgactc acgaaccggt tgagcattta
    44941 gcaggtcttc gtgctatgcc aaatctaaat gttttccgtc cagcagatgc gcgtgaaacg
    45001 caagcagctt ggtaccttgc agtgacaagt gagaaaacac caactgccct tgtcttgaca
    45061 cgtcaaaact tgactgttga agatggaaca gacttcgaca aggttgctaa aggtgcttat
    45121 gttgtatatg aaaatgcagc cgactttgat accatcttga ttgcgacagg ttcagaggtt
    45181 aatcttgctg tctcagctgc taaagaattg gctagtcaag gcgaaaaaat ccgcgtagtc
    45241 agcatgccat ctacagatgt ctttgataaa caagatgcag cttacaagga agagattctt
    45301 ccaaatgcag tccgccgtcg tgttgcagtc gaaatgggtg caagtcaaaa ctggtacaaa
    45361 tatgttggtc tcgatggtgc cgttctaggt attaatacct tcggagcctc tgccccagca
    45421 ccaaaagtat tggcagaata tggctttact gtagaaaatc ttgtaaaaat tgttcgaaac
    45481 ttgaaataat cctaaaaatc agggcgtaag ctctggtttt tcttaccaga aaagtaaggt
    45541 acaatcttgt aaaagtagct gaaatttgat atagtagtcc tatgtaaaag acaaaggaga
    45601 aaacaatgaa tccaaatatt acttttttaa tcatgcttgt aggtatgatg gccttgatgt
    45661 tctttatgca acgttctcaa aagaaacaag ctcaaaagcg tatggaaagc ttaaataaac
    45721 tacaaaaagg ctatgaagtg attacaatcg gtggacttta tggaacagtc gatgaagtag
    45781 atacggagaa gggaacaata gttcttgacg tagatggagt ttacttgact tttgaactag
    45841 ctgctatcaa gacagtatta ccgctgaaag aaacagcttc actagaaggc gcaattgaaa
    45901 aataagacgg gatcacgaac tcccgttttt ctataaaaga aaggaaatgg gatgaaaaaa
    45961 ttagtctttg tctgtctggg aaatatttgc cgtagcccta tggccgagtt tgttatgaaa
    46021 tcaatgacag ataactacga aatccaaagt cgagcaactt cctcttggga acatggcaat
    46081 ccgattcata aggggactca gggaattttt caagagtatg agattcctta tgacaagaac
    46141 aagacatcgc ttcagattag taaggaagat tttgaagcct ttgattatat tatcggaatg
    46201 gacgcttcaa atatttctga cttacgtcag atgtgtccag tagactgtca agataagatt
    46261 tactcatttt catctgaaag tgttccagac ccttggtata caggagattt tgaagaaacc
    46321 tatcgacgtg ttcaagaggg ctgtcaagct tggttagaac gtttagaaaa ggagagttaa
    46381 ggtggaaaat cttacgaatt tttacgaaaa gtatcgtgtc tatctgactc gtccacgatt
    46441 agagcttttg gcagtagtta ccattgtttt ctgtgctgta ctcgtctttt ttctaaatat
    46501 tccaggaaaa ggtgtcttaa aactcgataa tggaacgatt gtttatgatg gcagtcttgt
    46561 ccgtggtaaa atgaatggtc aaggtaccat taccttccaa aatggagacc aatatacagg
    46621 tggcttcaac aatggagcct tcaacggaaa aggtaccttt caatctaaag aaggctggac
    46681 ctacgaaggt gattttgtaa atggtcaggc tgaaggaaaa gggaaactaa caacagaaca
    46741 agaagtcgtt tatgaaggaa cttttaaaca aggcgttttt caacaaaaat aaagcctcct
    46801 tatcaaagga ggtattatta gaatcgcaag gtaagcgctt acctgcaaat ccctttcttt
    46861 ccaaatccct cttccaacca agtttgtgaa ataaaaaata tttgaaataa atttcacaaa
    46921 cttcaaagat aaaacctgat aagaaaagaa gatgagaaaa gtttcacaag agtttaaaaa
    46981 ttctttgtga aatgtttatg aaactgttta caaagttgaa ataatgcgtt ataataaact
    47041 tgtgaaaaaa ttaacaaagg atatcgttcc ttgaaagcta tggaggaaaa tatggctgat
    47101 aaaaaaactg tgacaccaga ggaaaagaaa ctcgttgctg aaaaacacgt agatgagttg
    47161 gttcaaaaag ctctagttgc ccttgaagaa atgcgtaaat tggatcaaga acaagttgac
    47221 tacatcgttg ccaaagcatc agtagcagct ttggatgccc acggagaatt ggctttacat
    47281 gcctttgaag aaacaggacg tggtgtattt gaagataaag caactaagaa cttgtttgct
    47341 tgtgaacacg tggtaaacaa catgcgtcac actaaaacag ttggcgttat cgaagaagat
    47401 gatgtaacag gattgaccct gattgctgaa ccagttggtg ttgtttgtgg tatcactcca
    47461 acaacaaacc caacatcaac agcgatcttc aaatcattga tttcattgaa gacacgtaat
    47521 ccaatcgtct ttgccttcca tccatcagct caagaatcat cagttcatgc agctcgtatc
    47581 gtccgcgatg cagctatcgc agctggtgct cctgaaaact gtgtacagtg gatcactgaa
    47641 ccatctatgg aagcaactag tgcccttatg aaccacgaag gtattgcaac aatccttgca
    47701 acaggtggta atgccatggt taaagccgca tactcatgtg gtaaaccagc tcttggggta
    47761 ggtgccggaa acgttccagc ttatgttgaa aaatcagcaa acattcgtca agcagcacac
    47821 gatatcgtca tgtctaaatc atttgataac ggtatggtct gtgcatctga acaagcagtt
    47881 atcattgata aagaaattta cgatgaattt gtagcagagt tcaaatctta ccacacttac
    47941 tttgtaaaca aaaaagaaaa agctcttctt gaagagttct gcttcggcgt caaagcaaac
    48001 agcaaaaact gtgctggtgc aaaattgaac gctgacatcg ttggtaaacc agcaacttgg
    48061 attgcagaac aagcaggatt tacagttcca gaaggaacaa acattcttgc tgcagaatgt
    48121 aaagaagttg gcgaaaatga gccattgact cgtgaaaaat tgtcaccagt tattgcagtt
    48181 ttgaaatctg aaagccgtga agatggtatt actaaggctc gtcaaatggt tgaatttaac
    48241 ggtcttggac actcagcagc tatccacaca gctgacgaag aattgactaa agaatttggt
    48301 aaagctgtta aagctattcg tgttatctgt aactcacctt ctacttttgg tggtatcggg
    48361 gacgtttaca atgccttctt gccatcattg acacttggat gtggttctta cggacgcaac
    48421 tcagttgggg ataacgttag tgccattaac ctcttgaata tcaaaaaagt cggaagacgg
    48481 agaaataaca tgcaatggat gaaacttcct tcaaaaacat actttgaacg tgattcaatt
    48541 caataccttc aaaaatgtcg tgacgttgaa cgtgtcatga tcgttactga ccatgccatg
    48601 gtagagcttg gtttccttga tcgtatcatc gaacaactgg accttcgtcg caataaggtt
    48661 gtttaccaaa tctttgcgga tgtagaaccg gatccagata tcacaactgt aaaccgtggt
    48721 actgagatta tgcgtgcctt cagaccagat accatcatcg cactcggtgg tgggtctcca
    48781 atggatgctg ccaaagtaat gtggctcttc tacgagcaac cagaagtgga cttccgtgac
    48841 cttgtccaaa aattcatgga tatccgtaaa cgtgccttca agttcccatt gcttggtaag
    48901 aagactaaat tcatcgcgat tccaactaca tctggtacag gatctgaagt aacaccattt
    48961 gccgttatct ctgataaagc aaacaaccgt aaatacccaa tcgctgacta ctcattgaca
    49021 ccaactgtgg caattgtaga ccctgctttg gtattgacag ttccaggatt tgttgctgct
    49081 gatactggta tggacgtatt gactcacgcg acagaagcat acgtatcaca aatggctagt
    49141 gactacactg atggtttagc acttcaagct attaaattgg tctttgaaaa tctcgaaagc
    49201 tcagttaaga atgcagactt ccactcacgt gagaaaatgc ataacgcttc aacaatcgct
    49261 ggtatggcct ttgccaatgc cttcctaggt atttctcact caatggccca taagattggt
    49321 gcgcaattcc acacaataca cggtcgtaca aatgctatct tgcttccata cgttatccgt
    49381 tacaacggta cacgtccagc taagacagca acatggccta agtacaacta ctaccgtgca
    49441 gatgaaaaat accaagatat cgcacgcatg cttggacttc cagcttctac tccagaagaa
    49501 ggggttgaat cttacgcaaa agctgtctac gaactcggtg aacgtattgg gatccaaatg
    49561 aattttagag accaaggaat tgacgaaaaa gaatggaaag aacattctcg tgaattagcc
    49621 ttcctggctt atgaagacca atgttcacca gctaacccac gtcttccaat ggtagaccat
    49681 atgcaagaaa tcatcgaaga tgcatactat ggctacaaag aaagaccagg acgccgtaaa
    49741 taattgttta tcagtctaga agcaagacaa aaactcaatt tgagggaaag atccagtaat
    49801 ttttctatga taaaaggcat cctatcaagg tttttgaaca cctgatagga tgccttttta
    49861 tgatattgag gcctttttgc cctttttgaa aaactagaat agaaacaaaa tatataatag
    49921 attgaaactg gaatagtaca cttctgcttc taaaacattg ttagaattcg atttgactgt
    49981 cc
//
LOCUS       DBEJKC010000006        48445 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.006, whole genome shotgun sequence.
ACCESSION   DBEJKC010000006 DBEJKC010000000
VERSION     DBEJKC010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 48445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48445
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.006"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            148..6834
                     /gene="bgaA"
                     /locus_tag="ACL3G6_000370"
     CDS             148..6834
                     /gene="bgaA"
                     /locus_tag="ACL3G6_000370"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000515226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored adhesin/beta-galactosidase BgaA"
                     /protein_id="HGR0544959.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SSQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVEEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAIRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTANVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEVTVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPSKLVLERYVGPGFEVPTYYSNYQAYESGHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKVGKERIFT
                     VINPDGSKEEKLREVVEVPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSEADQTN
                     KAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(7082..7219)
                     /locus_tag="ACL3G6_000371"
     CDS             complement(7082..7219)
                     /locus_tag="ACL3G6_000371"
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0544960.1"
                     /translation="MKPVFGQIKACLGYKRCNLRGKRQVRIDMGLVLMANNLLKHSEM
                     K"
     gene            complement(7216..7623)
                     /locus_tag="ACL3G6_000372"
     CDS             complement(7216..7623)
                     /locus_tag="ACL3G6_000372"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544961.1"
                     /translation="MEENDREILRQTSRTDTGLFSRRNPPLLIKYAMFDKKQKRGHKQ
                     SAKNLANWHYNDKEDSYTHPDGWYYRFHHTKHQKTQTDFQQEIKVYYADEPESVPQKG
                     LYMNERYQNLKAKECQALLSPEGRQISLNARLM"
     gene            complement(7691..7936)
                     /locus_tag="ACL3G6_000373"
     CDS             complement(7691..7936)
                     /locus_tag="ACL3G6_000373"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544962.1"
                     /translation="MHIHYNTNQTTLPLEISSFLPQDHLVFTIEKVVNTLEEHHFYAF
                     YHAFDRPSYHLKMLVSTLLFAYSQGIFSGRKIEKWKS"
     gene            complement(8148..8507)
                     /locus_tag="ACL3G6_000374"
     CDS             complement(8148..8507)
                     /locus_tag="ACL3G6_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HGR0544963.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKLSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            8599..9555
                     /locus_tag="ACL3G6_000375"
                     /pseudo
     CDS             8599..9555
                     /locus_tag="ACL3G6_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            9539..10096
                     /locus_tag="ACL3G6_000376"
     CDS             9539..10096
                     /locus_tag="ACL3G6_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0544964.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLDKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            10089..10343
                     /locus_tag="ACL3G6_000377"
     CDS             10089..10343
                     /locus_tag="ACL3G6_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544965.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            10355..12409
                     /locus_tag="ACL3G6_000378"
     CDS             10355..12409
                     /locus_tag="ACL3G6_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGR0544966.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLILPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETTIISSGAFVERVINRVKPNNIN
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            12588..13448
                     /locus_tag="ACL3G6_000379"
     CDS             12588..13448
                     /locus_tag="ACL3G6_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HGR0544967.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSINFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQFLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGVLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDQVFKKD"
     gene            13659..14369
                     /gene="ccdA2"
                     /locus_tag="ACL3G6_000380"
     CDS             13659..14369
                     /gene="ccdA2"
                     /locus_tag="ACL3G6_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGR0544968.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGFLVLFGNASILSQLFE"
     gene            14389..14955
                     /locus_tag="ACL3G6_000381"
     CDS             14389..14955
                     /locus_tag="ACL3G6_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HGR0544969.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            14966..16078
                     /gene="msrB"
                     /locus_tag="ACL3G6_000382"
     CDS             14966..16078
                     /gene="msrB"
                     /locus_tag="ACL3G6_000382"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGR0544970.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            16346..17083
                     /locus_tag="ACL3G6_000383"
     CDS             16346..17083
                     /locus_tag="ACL3G6_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR0544971.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            17080..18771
                     /locus_tag="ACL3G6_000384"
     CDS             17080..18771
                     /locus_tag="ACL3G6_000384"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0544972.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            18887..19450
                     /locus_tag="ACL3G6_000385"
     CDS             18887..19450
                     /locus_tag="ACL3G6_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HGR0544973.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALTSRPKLIGGARAHYPQDAIRKF"
     gene            19472..25192
                     /locus_tag="ACL3G6_000386"
     CDS             19472..25192
                     /locus_tag="ACL3G6_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGR0544974.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNYVNK
                     EIISQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYK
                     RKKIASVFLVGTMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTL
                     GLDTVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPK
                     EEPKSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPA
                     EESKVEQAGEPVAPRKDEQAPVEPENQPEAPEEEKAVEETPKQEESTPDTKAEETVEP
                     KEETVNQSIEQPKVETPAVEKQTEPTEEPKVEQAGEPVAPREDEQAPTAPVEPEKQPE
                     VPEEEKAVEETPKPEDKIKGIGTKEPVDKSELNNQIDKASSVSPTDYSTASYNALGPV
                     LETAKGVYASEPVKQPEVNSETNKLKTAIDALNVDKTELNNTIADAKTKVKEHYSDRS
                     WQNLQTEVTKAEKVAANTDAKQSEVNEAVEKLTATIEKLVELSEKPILTLTSTDKKIL
                     EREAVAKYTLENQNKTKIKSITAELKKGEEVINTVVLTDDKVTTETISAAFKNLEYYK
                     EYTLSTTMIYDRGNGEETETLENQNIQLDLKKVELKNIKRTDLIKYENGKETNESLIT
                     TIPDDKSNYYLKITSNNQKTTLLAVKNIEETTVNGTHVYKVTAIADNLVSRTADNKFE
                     EEYVHYIEKPKVHEDNVYYNFKELVEAIQNDPSKEYRLGQSMSARNVVPNGKSYITKE
                     FTGKLLSSEGKQFAITELEHPLFDKIKAGTVKNINFENIDINVSNQDNIATIANEING
                     TTRIENIKATGTITARNNVAGFVNNIKENAALENVAFIGNINSVGNNSTVGGIAGSNY
                     MGFVNKAYVDANITAANASASMLVPLVTYMLNSYQYGTKSKVTNSVAKGTLDVKNTRF
                     VGGVVAKTWPWGVIKDIVTYAKVIKGEEVYGSNEINDGDARQFLSDIYRVNGASSGAN
                     NFTNLQKIKQLTKEQADAKVATFNITADKLESELSPLAKLNEEKAYSSIQDYNAEYNQ
                     AYKNLEKLIPFYNKDYIVYQGNKLNKEHPLNTKEVLSVTAMNNNEFITNLDEANKIIV
                     HYADGTKDYFNLSSSSEGLSNVKEYTITDLGIKYTPNIVQKDNTTLVNDIKSILEPVD
                     LQSQTMYQHLNRLGDYRVNAIKDLYLEESFTAVKKNLTNLITKLVQNEEHQLNDSPAA
                     RQMLRDKVEKNKAALLLGLTYLNRYYGVKFGDVNIKELMLFKPDFYGEKVSVLDRLIE
                     IGSKENNIKGSRTFDAFGEVLAKYTKSGNLDVFLNYNRQLFTNIDNMNDWFIDATKDH
                     VYIAERASEVEEIKNAKYRAYANLNVAQHRKMILPLLNITKSHMFIASNYNAIAIGSA
                     EKLGKKSLEDIKASVDYAADGYRNYYDFWYRLVPDNVKQYLLRDTVIPIWEGYNAPGG
                     WVEKYGRYNTDNVYTPLREFFGPIEKYYGYNGTGAYAALYDNPMDPRSDVSYVALNMI
                     GDYGISVYTHETTHINDRKIYLGGFGRREGTDAEAFAQGMLQLPVPGSGFNEYGSLGL
                     NTVFKKPNDGNQWYDTDPKSLTTRDDIDKYMRGYNDALMLVDHLEADAVINQNNKELN
                     GAWFKKIDKKFRDASQLNQWDEIRNLTTEEKDNLNITSIDSLIDQQLMTNRQIGNRVY
                     KPEVVSQYDQSPYVGVEMTAGIYGGNTSKGAPGAVSFKHNAFRLWGYYGYLNGFLGYT
                     SNKYKQQSTKDGESVLSDEYIIKKISNNTFNTIEEFKKAYFKEVKDKATKGLTTFEVN
                     GSSVSSYDDLLTLFKEAVKKDAETLKQEANGHKTVSMTNTVKLKEAVYKKLLQQTDSF
                     KTSIFR"
     gene            25253..26974
                     /gene="pabB"
                     /locus_tag="ACL3G6_000387"
     CDS             25253..26974
                     /gene="pabB"
                     /locus_tag="ACL3G6_000387"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008153 - para-aminobenzoic acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HGR0544975.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKNLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            26975..27592
                     /locus_tag="ACL3G6_000388"
     CDS             26975..27592
                     /locus_tag="ACL3G6_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR0544976.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            27642..28640
                     /locus_tag="ACL3G6_000389"
     CDS             27642..28640
                     /locus_tag="ACL3G6_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
                     /protein_id="HGR0544977.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLTSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTV
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            28767..29726
                     /locus_tag="ACL3G6_000390"
     CDS             28767..29726
                     /locus_tag="ACL3G6_000390"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HGR0544978.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTVGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            29823..30662
                     /locus_tag="ACL3G6_000391"
     CDS             29823..30662
                     /locus_tag="ACL3G6_000391"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HGR0544979.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRIDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(30710..30880)
                     /locus_tag="ACL3G6_000392"
     CDS             complement(30710..30880)
                     /locus_tag="ACL3G6_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HGR0544980.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            31001..31885
                     /gene="miaA"
                     /locus_tag="ACL3G6_000393"
     CDS             31001..31885
                     /gene="miaA"
                     /locus_tag="ACL3G6_000393"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HGR0544981.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVLHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHFVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            31878..33116
                     /gene="hflX"
                     /locus_tag="ACL3G6_000394"
     CDS             31878..33116
                     /gene="hflX"
                     /locus_tag="ACL3G6_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HGR0544982.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKFQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDS
                     EVITGYISEKNKWRLEEFYD"
     gene            33109..33732
                     /locus_tag="ACL3G6_000395"
     CDS             33109..33732
                     /locus_tag="ACL3G6_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HGR0544983.1"
                     /translation="MTDIKALALKYGGYTSLDKVYLVQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     DSDGLGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            33747..34676
                     /gene="rnz"
                     /locus_tag="ACL3G6_000396"
     CDS             33747..34676
                     /gene="rnz"
                     /locus_tag="ACL3G6_000396"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HGR0544984.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTVRPRKISKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTNASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            34697..35452
                     /locus_tag="ACL3G6_000397"
     CDS             34697..35452
                     /locus_tag="ACL3G6_000397"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR0544985.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(35506..36414)
                     /locus_tag="ACL3G6_000398"
     CDS             complement(35506..36414)
                     /locus_tag="ACL3G6_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGR0544986.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLSHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            36478..36747
                     /locus_tag="ACL3G6_000399"
     CDS             36478..36747
                     /locus_tag="ACL3G6_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HGR0544987.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            36747..37127
                     /locus_tag="ACL3G6_000400"
     CDS             36747..37127
                     /locus_tag="ACL3G6_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGR0544988.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILRARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            37216..37443
                     /locus_tag="ACL3G6_000401"
     CDS             37216..37443
                     /locus_tag="ACL3G6_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544989.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLEYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(37483..38208)
                     /locus_tag="ACL3G6_000402"
     CDS             complement(37483..38208)
                     /locus_tag="ACL3G6_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HGR0544990.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            38370..40211
                     /gene="typA"
                     /locus_tag="ACL3G6_000403"
     CDS             38370..40211
                     /gene="typA"
                     /locus_tag="ACL3G6_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HGR0544991.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            40231..40485
                     /locus_tag="ACL3G6_000404"
     CDS             40231..40485
                     /locus_tag="ACL3G6_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HGR0544992.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            40849..41148
                     /locus_tag="ACL3G6_000405"
                     /pseudo
     CDS             40849..41148
                     /locus_tag="ACL3G6_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            41219..43240
                     /locus_tag="ACL3G6_000406"
     CDS             41219..43240
                     /locus_tag="ACL3G6_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGR0544993.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            43242..43883
                     /locus_tag="ACL3G6_000407"
     CDS             43242..43883
                     /locus_tag="ACL3G6_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0544994.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            43987..45339
                     /gene="murD"
                     /locus_tag="ACL3G6_000408"
     CDS             43987..45339
                     /gene="murD"
                     /locus_tag="ACL3G6_000408"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HGR0544995.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIATD
                     KNTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            45343..46401
                     /locus_tag="ACL3G6_000409"
     CDS             45343..46401
                     /locus_tag="ACL3G6_000409"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:0051991 -
                     UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-
                     glutamyl-meso-2,
                     6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol
                     4-beta-N-acetylglucosaminlytransferase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0007049 - cell cycle [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030259 - lipid glycosylation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HGR0544996.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            46411..47610
                     /gene="divIB"
                     /locus_tag="ACL3G6_000410"
     CDS             46411..47610
                     /gene="divIB"
                     /locus_tag="ACL3G6_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HGR0544997.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEESES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     NQRSSRR"
     gene            47741..47866
                     /locus_tag="ACL3G6_000411"
     CDS             47741..47866
                     /locus_tag="ACL3G6_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544998.1"
                     /translation="MSDEVFLFEEIEEIVAPTDGEFLGEVLLGTGVVLLIGVACC"
     gene            47887..48009
                     /locus_tag="ACL3G6_000412"
     CDS             47887..48009
                     /locus_tag="ACL3G6_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0544999.1"
                     /translation="MQDNFLFEEIEEISVPVSDFSAGLATGIGFGLAILALAGC"
BASE COUNT        15049 a         8876 c        10633 g        13887 t
ORIGIN      
        1 aatcatatct acggcaaggc gacactgacg aagtttgaat tggattttcg cagagtgtaa
       61 attgttgaaa ctaggttgtc ataccatgta taccacttgg gctttggtag tagctaactg
      121 cactaaatat aatataagga gggttttatg gggaaaggcc attggaatcg gaaaagagtt
      181 tatagcattc gtaagtttgc tgtgggagct tgctcagtaa tgattgggac ttgtgcagtt
      241 ctattaggag gaaatatagc tggagaatct gtagtttatg cggatgaaac acttattact
      301 catactgctg agaaacctaa agaggaaaaa atgatagtag aagaaaaggc tgataaagct
      361 ttggaaacta aaaatgtagt tgaaaggaca gaacaaagtg aacctagttc aactgaggct
      421 attgcatctg agaagaaaga agatgaagcc gtaactccaa aagaggaaaa agtgtctgct
      481 aaaccggaag aaaaagctcc aaggatagaa tcacaagctt caagtcaaga aaaaccgctc
      541 aaggaagatg ctaaagctgt aacaaatgaa gaagtgaatc aaatgattga agacaggaaa
      601 gtggatttta atcaaaattg gtactttaaa ctcaatgcaa attctaagga agccattaaa
      661 cctgatgcag acgtatctac gtggaaaaaa ttagatttac cgtatgactg gagtatcttt
      721 aacgatttcg atcatgaatc tcctgcacaa aatgaaggtg gacagctcaa cggtggggaa
      781 gcttggtatc gcaagacttt caaactagat gaaaaagacc tcaagaaaaa tgttcgcctt
      841 acttttgatg gcgtctacat ggattctcaa gtttatgtca atggtcagtt agtggggcat
      901 tatccaaatg gttataacca gttctcatac gatatcacca aataccttca taaagatggt
      961 cgtgagaatg tgattgctgt ccatgcagtc aacaaacagc caagtagccg ttggtattca
     1021 ggaagtggta tctatcgtga tgtgacttta caagtgacag ataaggtgca tgttgagaaa
     1081 aatgggacaa ctattttaac accaaaactt gaagaacaac aacatggcaa ggttgaaact
     1141 catgtgacca gcaaaatcgt caatacggac gacaaagacc atgaacttgt agccgaatat
     1201 caaatcgttg aacgaggtgg tcatgctgta acaggcttag ttcgtacagc gagtcgtacc
     1261 ttaaaagcac atgaatcaac aagcctagat gcgattttag aagttgaaag accaaaactc
     1321 tggaccgttt taaatgacaa acctgccttg tacgaattga ttacgcgtgt ttaccgtgac
     1381 ggtcaattgg ttgatgctaa gaaggatttg tttggttacc gttactatca ctggactcca
     1441 aatgaaggtt tctctttgaa tggtgaacgt attaaattcc atggagtatc cttgcaccac
     1501 gaccatgggg cgcttggagc agaagaaaac tataaagcag aatatcgccg tctcaaacaa
     1561 atgaaggaga tgggagttaa ctccatccgt acaacccaca accctgctag tgagcaaacc
     1621 ttgcaaatcg cagcagaact aggtttactc gttcaggaag aggcctttga tacttggtat
     1681 ggtggcaaga aaccttatga ctatggacgt ttctttgaaa aagatgccac tcacccagaa
     1741 gctcgaaaag gtgaaaaatg gtctgatttt gacctacgta ccatggtcga aagaggcaaa
     1801 aataaccctg ctatcttcat gtggtcaatt ggtaatgaaa taggtgaagc taatggtgat
     1861 gcccactctt tagcaactgt taaacgtttg gtcaaggtta tcaaggatgt tgataagact
     1921 cgctatgtta ccatgggagc agataaattc cgtttcggta atggtagcgg agggcatgag
     1981 aaaattgctg atgaactcga tgctgttgga tttaactatt ctgaagataa ttacaaagcc
     2041 cttagagcta agcatccaaa atggttgatt tatggatcag aaacatcttc agctacccgt
     2101 acacgtggaa gttactatcg ccctgaacgt gaattgaaac atagcaatgg acctgagcgt
     2161 aattatgaac agtctgacta tgggaatgat cgtgttggtt gggggaaaac agcaaccgct
     2221 tcatggactt ttgaccgtga caacgctggc tatgctggac agtttatctg gacaggtacg
     2281 gactatattg gtgaacctac accatggcac aaccaaaatc aaactcctgt taagagctct
     2341 tactttggta tcgtagatac agccggcatt ccaaaacatg acttctacct ctaccaaagc
     2401 caatgggttt ctgttaagaa gaaaccgatg gtacaccttc ttcctcactg gaactgggaa
     2461 aacaaagaat tagcatccaa agtagctgac tcagaaggta agattccagt tcgtgcttat
     2521 tcgaatgctt ctagtgtaga attgttcttg aatggaaaat ctcttggtct taagactttc
     2581 aataaaaaac aaaccagcga tgggcggact taccaagaag gtgcaaatgc taatgaactt
     2641 tatcttgaat ggaaagttgc ctatcaacca ggtaccttgg aagcaattgc tcgtgatgaa
     2701 tctggcaagg aaattgctcg agataagatt acgactgctg gtaagccagc ggcagttcgt
     2761 cttattaagg aagaccatgc gattgcagca gatggaaaag acttgactta catctactat
     2821 gaaattgttg acagccaggg gaatgtggtt ccaactgcta ataatctggt tcgcttccaa
     2881 ttgcatggcc aaggtcaact ggtcggtgta gataacggag aacaagccag ccgtgaacgc
     2941 tataaggcgc aagcagatgg ttcttggatt cgtaaagcat ttaatggtaa aggtgttgcc
     3001 attgtcaaat caactgaaca agcagggaaa ttcacactga cagcccattc agatctcttg
     3061 aaatctagtc aagtcactgt ctttactggt aaaaaagaag gacaagagaa gactgttttg
     3121 gggacagaag tgccaaaagt acagaccatt attggagagg cacctgaaat gcctaccact
     3181 gttccgtttg tatacagtga tggtagccgt gcagaacgtc ctgtaacctg gtcttcagta
     3241 gatgtgagca agcctggtat tgtaacggtg aaaggtatgg ctgacggacg agaagtagaa
     3301 gctcgtgtag aagtgattgc tcttaaatca gagctaccag ttgtgaaacg tattgctcca
     3361 aatactgact tgaattctgt agacaaatct gtttcctatg ttttgactga tggaagtgtt
     3421 gaagagtatg aagtggacaa gtgggagatt gccgaagaag ataaagctaa gttagcaatt
     3481 ccaggttctc gtattcaagc gaccggttat ttagaaggtc aaccaattca tgcaaccctt
     3541 gtggtagaag aaggcaatcc tgcggcacct gcagtaccaa ctgtaacggt tggtggtgaa
     3601 gctgtcacag gtcttactag tcaaaaacca atgcaatacc gcactcttgc ttatggagct
     3661 aagttgccag aagtcacagc aagtgctaaa aatgcagctg ttacagttct tcaagcaagc
     3721 gcagcaaacg gcatgcgtgc gagcatcttt attcagccta aagatggtgg ccctcttcaa
     3781 acctatgcaa ttcaattcct tgaagaagcg ccaaaaattg ctcacttgag cttgcaagtg
     3841 gaaaaagctg acagtctcaa agaagaccaa actgtcaaat tgtcggttcg agctcactat
     3901 caagatggaa cgcaagctgt attaccagct gataaagtaa ccttctctac aagtggtgaa
     3961 ggggaagtcg caattcgtaa aggaatgctt gagttgcata agccaggagc agtcactctg
     4021 aacgctgaat atgagggagc taaaggccaa gttgaactca ctatccaagc caatactgag
     4081 aagaagattg cgcaatccat ccgtcctgta aatgtagtga cagatttgca tcaggaacca
     4141 agtcttccag caacagtaac agttgagtat gacaaaggtt tccctaaaac tcataaagtc
     4201 acttggcaag ctattccgaa agaaaaacta gactcctatc aaacatttga agtactaggt
     4261 aaagttgaag gaattgacct tgaagcgcgt gcaaaagtct ctgtagaagg tatcgtttca
     4321 gttgaagaag tcagtgtgac aactccaatc gcagaagcac cacaattacc agaaagtgtt
     4381 cggacatatg attcaaatgg tcacgtttca tcagctaagg ttgcatggga tgcgattcgt
     4441 ccagagcaat acgctaagga aggtgtcttt acagttaatg gtcgcttaga aggtactcaa
     4501 ttaacaacta aacttcatgt tcgcgtatct gctcaaactg agcaaggtgc aaacatttct
     4561 gaccaatgga ccggttcaga attgccactt gcctttgctt cagattcaaa tccaagcgac
     4621 ccagtttcaa atgttaatga caagctcatt tcctacaata accaaccagc caatcgttgg
     4681 acaaactgga atcgtagtaa tccagaagct tcagtcggtg ttctgtttgg agattcaggt
     4741 atcttgagca aacgctccgt tgataatcta agtgtcggat tccacgaaga ccatggagtt
     4801 ggtgcaccga agtcttatgt gattgagtat tatgttggta agactgtccc aacagctcct
     4861 aaaaacccta gttttgttgg taatgaggac catgtcttta atgattctgc caactggaaa
     4921 ccagttacta atctaaaagc ccctgctcaa ctcaaggctg gagaaatgaa ccactttagc
     4981 tttgataaag ttgaaaccta tgctattcgt attcgcatgg ttaaagcaga taacaagcgt
     5041 ggaacgtcta tcacagaggt acaaatcttt gcgaaacaag ttgcggcagc caaacaagga
     5101 caaacaagaa tccaagttga cggcaaagac ttagcaaact tcaaccctga tttgacagac
     5161 tactaccttg agtctgtaga tggaaaagtt ccggcagtca cagcaaatgt tagcaacaat
     5221 ggtctcgcta ccgtcgttcc aagcgttcgt gaaggtgagc cagttcgtgt catcgcgaaa
     5281 gctgaaaatg gcgacatctt aggagaatac cgtctgcact tcactaagga taagaactta
     5341 ctttctcata aaccagttgc tgcggttaaa caagctcgct tgctacaagt aggtcaagca
     5401 cttgaattgc cgactaaggt tccagtttac ttcacaggta aagacggcta cgaaacaaaa
     5461 gacctgacag ttgaatggga agaagttcca gcggaaaatc tgacaaaagc aggtcaattt
     5521 actgttcgag gccgtgtcct tggtagtaac cttgttgctg aggtcactgt acgagtgaca
     5581 gacaaacttg gtgagactct ttcagataac cctaactatg atgaaaacag taaccaggcc
     5641 tttgcttcag caaccaatga tattgacaaa aactctcatg accgcgttga ctatctcaat
     5701 gacggagatc attcagaaaa tcgtcgttgg acaaactggt caccaacacc atcttctaat
     5761 ccagaagtat cagcgggtgt gatcttccgt gaaaatggta agattgtaga acggactgtt
     5821 gctcaagcca aacttcactt ctttgcagat agtggtacgg atgcaccatc taaactcgtt
     5881 ttagaacgct atgtcggccc aggctttgaa gtacctacct actattcaaa ctaccaagcc
     5941 tacgaatctg gacatccatt taacaatcca gaaaattggg aagctgtgcc ttatcgtgcg
     6001 gataaagaca tcgcagctgg tgatgaaatc aacgtaacat ttaaagctgt caaagccaaa
     6061 gccatgagat ggcgtatgga gcgtaaagct gacaagagcg gtgttgcgat gattgagatg
     6121 accttccttg caccaagtga attgcctcaa gaaagcacgc aatcaaagat tcttgtagat
     6181 ggaaaagaac ttgctgattt cgctgaaaat cgtcaagact atcaaattac ctataaaggt
     6241 caacggccaa aagtctcagt tgaagaaaac aatcaagtag cttcaactgt ggtagatagt
     6301 ggagaagata gccttccagt acttgttcgc ctcgtttcag aaagtggaaa acaagtcaag
     6361 gaataccgta tccagttgac taaggaaaaa ccagtttctg ctgtacaaga agatcttcca
     6421 aaactcgaat ttgttgaaaa agatttggcc tacaagacag ttgagaaaaa agattcaaca
     6481 ctgtatctag gtgaaactcg tgtagaacaa gaaggaaaag ttggaaaaga acgtatcttt
     6541 acagtgatta atcctgatgg aagtaaggaa gaaaaactcc gtgaagtggt agaagttccg
     6601 acagaccgca tcgtcttggt tggaaccaaa ccagtagctc aagaagctaa aaaaccacaa
     6661 gtgtcagaaa aagcagatac aaaaccaatt gattcaagtg aagctgatca aactaataaa
     6721 gcccagttac caaatacagg tagtgcggca agccaagcag cagtagcagc aggtttagct
     6781 cttctaggtt tgagtgcagg attagtagtt actaaaggta aaaaagaaga ctagaaattt
     6841 tgataccttc tttatcatta aagaccaaag aaaaactctt gtcctaaata gaagataaag
     6901 agtctggaac aaaatagttc tcaaccacaa aaaagctaga tatttccaat tgcggaactc
     6961 tagcttttta attttgagtc gttctcttat tgtatagtag attgaaacta gaatagtaca
     7021 cttctacttc taaaacattg ttagaaatca atttgactgt ccttatcgat ttgtcctggt
     7081 cttatttcat ttcactatgt tttaggaggt tattggccat aagtaccaat cccatgtcaa
     7141 ttctcacttg acgcttccct ctcagattac atctcttgta acccaaacaa gcctttatct
     7201 gcccaaagac aggtttcaca tcaatcttgc gttgagcgaa atctgtctac cttcaggaga
     7261 taaaagcgcc tgacattctt tagctttcaa gttttgatag cgttcgttca tatacagtcc
     7321 cttttgaggg actgattcag gttcatcagc gtagtaaacc ttgatttcct gttgaaagtc
     7381 tgtctgtgtt ttctgatgtt tggtatggtg aaaacgataa taccagccat caggatgtgt
     7441 gtagctatcc tccttgtcat tatagtgcca attcgctaag tttttagctg actgtttatg
     7501 tcctctcttt tgtttcttat caaacatggc atatttaatc agaaggggag gatttcttct
     7561 tgaaaataga cctgtatctg ttcttgaagt ttggcggaga atttctctgt cgttttcttc
     7621 cacacaaaac tatacttgtt ggcattggct tcaatcttag ttccgtcaat aaacaaacaa
     7681 tctaaggtca ctaactcttc catttttcaa tttttcgacc agagaaaatc ccttgtgaat
     7741 aggcaaatag aagagtagat acaagcattt taaggtgata agacgggcga tcaaaggcat
     7801 gatagaaggc gtagaagtga tgttcctcca aggtattcac cactttttca atagtaaaga
     7861 cgagatggtc ttgtggtaag aaggaactga tttctagtgg taaagttgtt tgatttgtgt
     7921 tatagtgaat atgcatggga tagcctttct aaatggttta ttgggcaatt ctattttacc
     7981 aagactatcg taaccatgca aaaaaagcaa cggcaaatcc gttgcttttt ttggagataa
     8041 gagactattg tcccagactc ttttctttgt ataaaattgt atagtgttat tgtctatact
     8101 attttgtaga gaaagcaaaa atccctagaa aatgcttagg gattcgacta tttcattaag
     8161 aacaattcaa caatcatttc tatatacatg ataagggtta ataagaatcc tgcacgccag
     8221 aagaatttga tgaatttagg atagtaaaag ctgagttttt tcaaaaggaa gaaaaagacg
     8281 agaataatgg ctaggattga gagggctagc cccagtctag ggaggaaatt atgggtaaag
     8341 gttttagctg taatcaggta atattcaaat accaagaccg gaaaagccaa atccgcaaag
     8401 tttcgtccta gtttttttaa tctaaaaagt ttggttagga taatgcagac gactaaggtc
     8461 agtatcaata ataaaataga tgctaatttc attaaaatca tacccatatt gtatcataaa
     8521 aaaaagctaa tggaaacgag aaacagagga atttatagga aagtcaggct tttgagattg
     8581 tgggtgattt ttgttataat gaaagttata aaatcttata ataccttgaa tgattattat
     8641 cgaaaactct ttggagaaaa gacttttaaa gtccctattg atgcggaatt tgactgtccc
     8701 aatcgtgatg gaactgtggc tcatggaggc tgtacttttt gtacggtttc aggttctgga
     8761 gatactattg tagccccaga tgcgcctatc cgtgagcaat tttataagga aattgacttt
     8821 atgcaccgta agtggccgga tgttcagaag tatctggttt attttcaaaa ttttaccaac
     8881 acccatgaaa aggtggaagt tattcgagag cgttatgaac aggctatcaa tgagccaggt
     8941 gtggtaggaa tcaatattgg aatgcgccca gactgtttac cagacgaaac catcgaatat
     9001 ttggctgagt tatcggagtg catgcatgtg acggttgaat tgggcttgta gactacttat
     9061 gaagcaactt ctgacctgat taaccgtgcg tattcttatg aattgtaggt ggaaacggtc
     9121 aagcgtttga gaaagtatcc caagattgag attgtttccc atttgattaa tggtttgcct
     9181 ggtgaaaccc atgagatgat ggttgaaaat gtccgccgtt gtgtcacgaa taacgatatt
     9241 caagggatta aactgcattt gctccatctt atgacaaata ctcgtatgca acgagattac
     9301 catgagggac gtttacaatt gatgagtcag gacgaatatg tcagggtcat ctgtgaccaa
     9361 ctggaaatca ttcccaaaca tatcgtcatc catcgaatca caggagatgc acctagggat
     9421 atgctgattg ggcttatgtg gagcctcaat aaatgggaag ctctcaacag cattgagatg
     9481 gagatgcgac gtcgtggaag tgttcaagga tgcaaggctg taaaacagga gtttgaaaat
     9541 gaaaagacca cttgagatgg cacatgattt tttggctgag gtcgtgacaa aagaggatgt
     9601 cgtagtggat gcgactatgg gaaatggtca tgacacgctt tttttagcca agctagacaa
     9661 gcaagtctat gcctttgata ttcagaagca agccttggaa aagacccaag agcgtttgca
     9721 tcaggctggc ttgacaaatg cccagttaat cttgcaaggc catgagacac tggaccagtt
     9781 tgtgacaaaa gctaaggcag ggatttttaa tttgggctat ttgccgtcag ctgataagtc
     9841 tgtcatcacc cgaccgcaga caacgattga ggcattagaa aagctatgtg gcttacttgt
     9901 caagggtgga cgaattgcta ttatgattta ctatggtcat gaaggaggcg acctcgagag
     9961 agatgctgtc ttggattttg taatccagtt gaaccaacaa gagtacacag ctgccattta
    10021 ccgaacttta aaccaagtca acaacccgcc gtttttagtg atgattgaaa aattagagag
    10081 atacagacat ggataaacaa tacctacacg aaaagctgga tgccatgcgc cagaattttg
    10141 ttgaatcaac ccaccacgaa cgatcggtgg gcgtgctaga ccaagcgcat atgagcaaaa
    10201 aaatgcttaa aatcaagaaa aaattagttg ctcttgaaat ggaacggtgc cagagaaaaa
    10261 ttgagcacaa agactgttcc aagattgacc aaaaaatcaa agagcagaag gagatatttg
    10321 aatcctgttg taaaaaagat taaggaggac gtgcgtggaa ttactgattt acctcatcct
    10381 atttttactg gttttgattg tctcaagtac aaccaataag ctcctgccct ttttgcctct
    10441 ccctttggtg caaattcttt tgggaattgt gattggtctc tttttaccca ataccgactt
    10501 tcacctcaat acggagttgt ttttggccct ggttatcgga cccttgcttt tccgagaggc
    10561 tgaagaagca gatgttacgg ctattttaaa acactggcga atcattgttt atctcatatt
    10621 tccagtgatt tttatctcga ccctgagttt gggtggcttg gcccatcttc tttggttcag
    10681 ccttcccttg gcagcttgct tggctgttgg ggcagccctt ggtcctacgg acttggtggc
    10741 ctttgcctct ctttcggagc gttttagctt tcctaagcgc gtgtccaata ttcttaaggg
    10801 cgaaggactc ttgaatgatg cttctggttt ggtggctttt caggtagctt tgacagcttg
    10861 gacaactgga gctttttctc tggggcaagc tagcagttcg ctcatctttt caatcctagg
    10921 cggtttttta attggatttt taacagccat gaccaaccgc ttcctccata ccttcttgct
    10981 aagtgtgcgc gcaacggata ttgccagtga acttttatta gaattaagtt tgcctctagt
    11041 gaccttcttt ctggcagaag aagttcatgt ttcagggatt attgccgtcg tagttgctgg
    11101 aattttaaag gcaagtcgtt tcaagaaaat cacgctcctc gaagcccaag tggatacggt
    11161 gaccgagacg gtctggcata cagtgacctt tatgctcaac ggttctgtct ttgtgatttt
    11221 agggatggag ttggaaatga tagcagaacc tatcttgacc aatccaatct ataatcctct
    11281 acttttattg ctatctctca tcgcccttac ctttgtcctc tttgtcattc gttttattat
    11341 gatctatggc tattatgcct atagaacccg acgcctcaag aaaaagctaa ataagtatat
    11401 gaaggacatg tttctcttga ccttttcagg tgttaaggga acggtgtcga ttgctacgat
    11461 tctcttgata ccaagtaatc tagaacaaga gtatcctctt ttgcttttcc ttgttgcagg
    11521 tgtgacgctt gtcagctttt taacaggtct cttgatcttg cctcatcttt ctgatgaaga
    11581 ggaagaaagc aaggattatc tcatgcatat cgccattttg aatgaagtaa cgctagagtt
    11641 ggaaaaagag ttggaagaca ccagaaataa acttcccctc tatgcggcta ttgacaatta
    11701 tcatggacgt attgaaaatc tcattttaag ccaagaaaac caggatgatc aagaagactg
    11761 ggctgctttg aaactcttga ttcttagtat tgaaagtgat ggtttggaac aggcctatga
    11821 agaggggaac attagcaatc gtgcttaccg agtttaccaa cgttatctga aaaatataga
    11881 acaaggaatc aatcgtaaac ttgcctcaag actgacctat tattttcttg tttccttgag
    11941 gattttacgt tttctccttc atgaagtttt tactcttgga aagaccttcc gtagctggaa
    12001 ggacaaggag caaagccgtc tccgtgctct tgattatgac caaattgcag agctctatct
    12061 tgccaatacg gagatgatta ttgaaagttt ggaaaacctg aagggagtct acagacgctc
    12121 tttgattagt tttatgcagg agtctcgtct tcgagaaaca actattatca gcagtggtgc
    12181 atttgtcgaa cgggttatca atcgtgtcaa acccaacaat atcaatgaaa tgctgagagg
    12241 ctattatctg gagcgcaagt tgattttcga atacgaagaa aaacgattaa ttacaactaa
    12301 gtatgccaag aaattacgac aaaatgtaaa taacttagag aactattcct tgaaggaagc
    12361 tgccaatacc ctgccgtatg atatggtgga attggtaaga agaaattagt taatactctt
    12421 cgaaaatctc ttcaaaccac gtcagcgtcg ccttaccgta tgtatgtgac tgacttcgtc
    12481 agtcttatct acaacctcaa aacagtgttt tgagcagctt gcggctagct ttctagtttg
    12541 ctctttgatt ttcattgagt ataagattat aaatgaagga gtatgacatg aaaaagtggt
    12601 ggaaagagct gatagacaag cctttattaa aagctttttt gcattattat caagcatcag
    12661 atagtgagtt gaccagtgtc gcagtagcct actattggtt gatttcgatt ttccccctgc
    12721 ttttggtggt ggtcaatatc ctcccctatt ttcagattcc tgtgggagaa tttctgggct
    12781 ttatgaaaga cgtcctgccc ccaagcctct atgaaggtgt ggaaaaaata gccagagaag
    12841 tcttgacgca accttcaaca ggtttattga gtttttctgt tttatcggcg ttatggagtt
    12901 tttcaaaatc tataaatttc ttgcaaaaag cttttaacaa ggcttatggc gtcgaaaaga
    12961 gtcgtggact tatttcccat cagatgctaa gtctcctagt cagttttggc ttgcagttcc
    13021 tctttgcgtt tgccttgttt ttgatcttat ttggtcagat gattttggct ttacttgctc
    13081 attattggac aaaagatggc attatctatc aggctttaca agggttggca ggtcctctga
    13141 tttacgccct cctctttgct atcttggtca tgctttatta ttttcttccc aatctatcta
    13201 acaggaaaat tagctatacc ctaccaggca gtgcctttgt tctcttggtg attttaggtg
    13261 tactaactct gttctctagt tatctcaatt actatgtcca tcatttggtg gatgtccgaa
    13321 ttttaggttc cgttcttctt gttgttatga tgttttggtt tatcttgatt gctaaaattg
    13381 ttatcctagg cgcggtgatc aatgccagta tgcagagttt gaaagatcag gtctttaaaa
    13441 aagactaact atttatccat tacaaaagcg catagtatca aggctttata gaatcttgat
    13501 actatgcgct tttgtgcttt gacagttttt tgtatagttt ttgtccaaga tttctaaatc
    13561 atctgattaa attcctattt tcccctatca ttgtccctgt tttttcgaaa atggaaggag
    13621 tataataaat ctatcaataa aatgatagga ggaactttat gggtcatatt ttcttttttc
    13681 taagtgtctt tttggcaggg attctatcct tcttttctcc ttgtatctta cctttgttac
    13741 cggtctatac aggagtgtta ctagatgata aggatggtgc tcaggcttct agcggcaaat
    13801 tttcaatctc agttactagt ttattacgaa ctctggcctt tatagcagga atttccttta
    13861 tatttatttt gttgggctat ggagctggtt ttttaggcga tttgctttat gcttcttggt
    13921 tccaatatct tactggggca attattatcc ttcttggttt gcaccaaatg gagattctac
    13981 actttaaggg gctttataag gaaaagaggc tacaactgca aggacagggg caaaatggta
    14041 agggctatag tcaggcattt ttattgggct tgacctttag ttttgcttgg acgccttgcg
    14101 tggggccggt tctggggtct gttttggcct tggcggcttc aggtggttca ggagcttggc
    14161 agggagctgg tctcatgttg gtgtatacgc tgggcttggc gctaccattc ttgcttctag
    14221 ctctgacctc tagttatgtt ttgaaacatt tccgaaaact tcatccctat ctcggaatcc
    14281 tcaaaaaagt gggtggtttt ctcattattg tgatgggatt cttggttctg tttggaaatg
    14341 cttcaatttt aagtcaatta tttgaataaa atggaaagga atatcaatat gaaaaaatgg
    14401 caaacatgtg ttcttggagc aggttcgctc ctttgtttga cggcttgttc aggcaagtcc
    14461 gtgactagtg aacaccaaac gaaagatgaa atgaagacgg agcagacagc tagtaaaaca
    14521 agcgcagcta aagggaaaga ggtggctgat tttgaattga tgggagtaga tggcaagacc
    14581 taccgtttat ctgattacaa gggcaagaaa gtctatctca aattctgggc ttcttggtgt
    14641 tccatctgtc tggctagtct tccagatacg gatgagattg ctaaagaagc tggtgatgac
    14701 tatgtggtct tgacagtagt gtcaccagga cataagggag agcaatctga agcggacttt
    14761 aagaattggt ataagggatt ggattataaa aatctcccag tcctagttga cccatcaggc
    14821 aaacttttgg aaacttatgg tgtccgttct tacccaaccc aagcctttat agacaaagaa
    14881 ggcaagctgg tcaaaacaca tccaggattc atggaaaaag atgcaatttt gcaaactttg
    14941 aaggaattag cctaggaggc gtcttatgaa tgataagtta aaaatcttct tgttgctagg
    15001 agtatttttt ctagccataa ccggtttcta tgttctattg atacgaaatg cagggcagac
    15061 agatgcctcg caaattgaaa aggcggcagt tagccaagga ggaaaagcag tgaaaaaaac
    15121 agaaattagt aaagacgcag acttgcacga aatttatcta gctggaggtt gtttctgggg
    15181 agtggaggaa tatttctcac gtgttcccgg ggtgacggat gccgtttcag gctatgcaaa
    15241 tggtagagga gaaacaacca agtacgaatt gattaaccaa acaggtcatg cagaaaccgt
    15301 ccatgtcacc tatgatgcca agcaaatttc tctcaaggaa atcctgcttc actatttccg
    15361 cattatcaat ccaaccagca aaaataaaca aggaaatgat gtggggaccc agtaccgtac
    15421 tggtgtttat tacacagatg acaaggattt ggaagtgatt aaccaagtct ttgatgaggt
    15481 ggctaagaaa tacgatcaac ctctagcagt tgaaaaggaa aacttgaaga attttgtggt
    15541 ggctgaggat taccatcaag actatctcaa gaaaaatcca aatggctact gccatatcaa
    15601 tgttaatcag gcggcctatc ctgtcattga tgccagcaaa tatccaaaac caagtgatga
    15661 ggaattgaaa aagaccctgt cacctgagga gtatgcagtt acccaggaaa atcaaacaga
    15721 acgagctttc tcaaaccgtt actgggataa atttgaatcc ggtatctatg tggatatagc
    15781 aactggggaa cctctctttt catcaaaaga caaatttgag tctggttgtg gctggcctag
    15841 ttttacccaa cccatcagtc cagatgttgt cacctacaag gaagataagt cctacaatat
    15901 gacgcgtatg gaagtgcgga gccgagtagg agattctcac cttgggcatg tctttacgga
    15961 tggtccacag gacaagggcg gcttacgtta ctgtatcaat agcctctcta tccgctttat
    16021 tcccaaagac caaatggaag aaaaaggcta cgcttattta ctagattatg ttgattaata
    16081 ctcttcgaaa atctcttcaa accacgtcag cgtcgcctta ccgtatgtag ggttactgac
    16141 ttcgtcagtt ttatctacaa cctcaaagct atactttgag ctgacttcgt cagttttatt
    16201 tacaacctca aagctatact ttgagaaacc tgtggctatc ttcctagttt actttttgat
    16261 ttttattgag tataagaggt ctttcctaag cagttagagg agaattttgc tatactgata
    16321 ctagtaagtg gtaaaggagc agagcatgac ctacacaatc ttaatcgtag aagatgaata
    16381 tctggtaaga caaggtttga ctaaactggt caatgtagca gcctacgata tggaaatcat
    16441 cggtcaggct gaaaatggaa ggcaggcttg ggaattgatc caaaagcagg tgccagatat
    16501 cattttaacc gatatcaaca tgcctcatct aaatggcatc cagttggcca gtctggtacg
    16561 agaaacctat cctcaggttc atttggtctt tttaacaggt tacgatgatt ttgattatgc
    16621 cttgtctgct gtcaaactag gtgtggacga ctacctgctc aaaccctttt ctcgtcagga
    16681 tattgaggaa atgttgggga aaatcaaaca aaaactagac aaggaagaga aagaagagca
    16741 gttacaagat ttattgacta ataggtttga aggaaacatg gcccagaaaa tccagtctca
    16801 tctggctgat agccaattta gtttaaagtc tttagccagt gacttaggtt ttagtccgac
    16861 ctatctgagt tccttgatta agaaagagtt gggcttgcct tttcaggatt atctggtgag
    16921 agaacgtgtt aaacaagcca agctcttgct tttaactaca gatctgaaga tttatgagat
    16981 cgcagagaag gttggttttg aagatatgaa ctattttacc caacgtttta agcagattgc
    17041 aggtgtgaca cctcgtcagt ttaagaaggg agaagaccga tgaagcgttc ttctctttta
    17101 gttagaatgg ttatttccat ctttctggtc tttctcattc tcctagctct ggttggaact
    17161 ttctactatc aatcaagttc ttcagccatt gaggccacca ttgagggcaa cagccaaacg
    17221 accatcagcc agactagcca ctttattcag tcttatatca aaaaactaga aaccacctcg
    17281 actggtttga cccagcagac ggatgttctg gcctatgctg agaatcccag tcaagacaag
    17341 gtcgagggaa tccgagattt gtttttgacc atcttgaagt cagataagga cttgaaaact
    17401 gttgtgctgg tgaccaaatc tggtcaggtc atttctacag atgacagtgt gcagatgaaa
    17461 acttcctctg atatgatggc tgaggattgg taccaaaagg ctattcatca gggagctatg
    17521 cctgttttga ctccagctcg taaatcagat agtcagtggg tcatttctgt cactcaagaa
    17581 cttgttgatg caaagggagc caatcttggt gtgcttcgtt tggatatttc ttatgaaact
    17641 ctggaagcct atctcaatca actccagttg gggcagcagg gctttgcctt cattatcaat
    17701 gaaaaccatg aatttgtcta ccatcctcaa cacacagttt atagttcgtc tagcaaaatg
    17761 gaggctatga aaccctacat cgagacaggt cagggttata ctcctggtca caaatcctac
    17821 gtcagtcaag agaagattgc aggaactgat tggacggtac ttggcgtgtc atcattggaa
    17881 aagttagacc aggttcggag tcagctcttg tggaccttgc ttggggccag tgtcacatct
    17941 cttcttgtct gtctctgctt agtgtggttc agtcttaaac gctggattgc tcctttgaag
    18001 gatttgagag aaaccatgtt ggaaattgct tctggtgctc aaaatcttcg tgccaaggaa
    18061 gttggtgcct atgaactgag agaagtaact cgccaattta atgccatgtt ggatcagatt
    18121 gatcagttga tggtagctat tcgtagccag gaagaaacga cccgtcagta ccaacttcaa
    18181 gccctttcga gccagattaa tccacatttc ctctataaca ctttggacac catcatctgg
    18241 atggctgaat ttcatgatag tcagcgagtg gtgcaggtga ccaagtcctt ggcaacctat
    18301 ttccgcttgg cgctcaatca aggcaaggac ttgatttgtc tctctgacga aatcaatcat
    18361 gtccgccagt atctctttat ccagaaacaa cgctatggag ataagctgga atacgaaatt
    18421 aatgaaaatg ttgcctttga taatttagtc ttacccaagc tggtcctaca accccttgta
    18481 gaaaatgctc tttaccatgg cattaaggaa aaggaaggtc agggccatat taaactttct
    18541 gtccagaaac aggattcggg attggtcatc cgtattgagg atgatggcgt tggcttccaa
    18601 gatgctggtg atagtagtca aagtcaactc aaacgtgggg gagttggtct tcaaaatgtc
    18661 gatcaacggc tcaaacttca ttttggagcc aattaccaga tgaagattga ttctagaccc
    18721 caaaaaggaa cgaaagttga aatatatata aatagaatag aaactagcta actcccagtc
    18781 aattctggga gttttatgcg taattgggca aactttctag gttgtctatc ttgctaaaaa
    18841 caagaaaaaa cggtatgata gaagagtgac aacagaggta acagagatga acgagacaca
    18901 gattcaaaga gaaacacgtc aggtagtgga agatgtttta gaaaagacca atttgaaaca
    18961 gggggccctt tttgttttag gtctatcttc tagtgaggtg ctaggtggtc agattgggaa
    19021 agaatccagt caagagattg gtgagctgat agtggagact atcttgggta ttctaggtag
    19081 tagaggtatc catttagcag ttcaaggttg tgagcatgtc aatcgggctc tcgttgttga
    19141 acgtcaggtg gcagagcagt ttggtctgga aattgtcagt gtccatccta ctcttcatgc
    19201 aggaggttcg gggcagttgg cagcctttaa gtttatgcag gatccagttg aggttgaatt
    19261 tatcaaggct catgctggat tggatatcgg agacactgca attggcatgc atgtcaagca
    19321 tgttcaggtt ccgattcgcc ctattttgag agagattggt catgcccatg taacggcact
    19381 gactagtcgt ccaaaattaa tcggaggtgc gcgtgcgcac tatccgcaag atgctattag
    19441 gaagttttga gaatgaataa aggagataaa agtgtttaaa aaagaccgtt tttcaattcg
    19501 taagattaag ggagttgtag gctctgtatt tcttggaagc cttttgatgg ctccttctgt
    19561 agtggacgca gccacctatc actatgtaaa ttatgtaaat aaagagatta tttcacaaga
    19621 agctaaagat ttaattcaga caggaaagcc tgacaggaat gaagttgtat atggtttggt
    19681 gtatcaaaaa gatcagttgc ctcaaacagg gacagaagca tctgttttga cagcttttgg
    19741 tttgctgact gttgggagct tgcttttaat ctacaagaga aagaaaattg ctagcgtctt
    19801 tctagttgga actatgggat tggtagttct tcctagtgca ggggctgtag acccagttgc
    19861 gaccctagca ctggctagtc gagagggtgt tgttgaaatg gagggctatc gctatgttgg
    19921 ttatctatca ggtgacatcc tcaaaacgct tggcttggac actgttttag aagaaacctc
    19981 agcaaaacct ggagaggtga ctgtagtcga agttgagact cctcaatcaa caacaaatca
    20041 ggagcaagct aggacagaaa accaagtagt agagacagag gaagctccaa aagaagaagc
    20101 acctaaaaca gaagaaagtc caaaggaaga accaaaatcg gaggtaaaac ctactgacga
    20161 cacccttcct aaagtagaag aggggaaaga agattcagca gaaccagctc cagttgaaga
    20221 agtaggtgga gaagttgagt caaaaccaga ggaaaaagta gcagttaagc cagaaagtca
    20281 accatcagac aaaccagctg aggaatcaaa agttgaacaa gcaggtgaac cagtcgcgcc
    20341 aagaaaagac gaacaggcac cagtcgagcc agaaaatcaa ccagaagctc ctgaagaaga
    20401 gaaggctgta gaggaaacac cgaaacaaga agagtcaact ccagatacca aggctgaaga
    20461 aactgtagaa ccaaaagagg agactgttaa tcaatctatt gaacaaccaa aagttgaaac
    20521 gcctgctgta gaaaaacaaa cagaaccaac agaggaacca aaagttgaac aagcaggtga
    20581 accagtcgcg ccaagagaag acgaacaggc accaacggca ccagttgagc cagaaaagca
    20641 accagaagtt cctgaagaag agaaggctgt agaggaaaca ccgaaaccag aagataaaat
    20701 aaagggtatt ggtactaaag aaccagttga taaaagtgag ttaaataatc aaattgataa
    20761 agctagttca gtttctccta ctgattattc tacagcaagt tacaatgctc ttggacctgt
    20821 tttagaaact gcaaaaggtg tctatgcttc agagcctgta aaacagcctg aggtaaatag
    20881 cgagacaaat aaacttaaaa cggctattga cgctctaaac gttgataaaa ctgaattaaa
    20941 caatacgatt gcagatgcaa aaacaaaggt aaaagaacat tacagtgata gaagttggca
    21001 aaacctccaa actgaagtta caaaggctga aaaagttgca gctaatacag atgctaaaca
    21061 aagtgaagtt aacgaagctg ttgaaaaatt aactgcaact attgaaaaat tggttgaatt
    21121 atctgaaaag ccaatattaa cattgactag taccgataag aaaatattgg aacgtgaagc
    21181 tgttgctaag tatactctag aaaatcaaaa caaaacaaaa atcaaatcaa tcacagctga
    21241 attgaaaaaa ggagaagaag ttattaatac tgtagttctt acagatgaca aggtaacaac
    21301 agaaactata agcgctgcat ttaagaacct agagtactac aaagaataca ccctatctac
    21361 aactatgatt tacgacagag gtaacggtga agaaactgaa actctagaaa atcaaaatat
    21421 tcaattagat cttaaaaaag ttgagcttaa aaatattaaa cgtacagatt taatcaaata
    21481 cgaaaatgga aaagaaacta atgaatcact gataacaact attcctgatg ataagagcaa
    21541 ttattattta aaaataactt caaataatca gaaaactaca ttactagctg ttaaaaatat
    21601 agaagaaact acggttaacg gaacacatgt atataaagtt acagcaatcg cagacaattt
    21661 agtctctaga actgctgata ataaatttga agaagaatac gttcactata ttgaaaaacc
    21721 taaagtccac gaagataatg tatattataa tttcaaagaa ttagtggaag ctattcaaaa
    21781 cgatccttca aaagaatatc gtctgggaca atcaatgagc gctagaaatg ttgttcctaa
    21841 tggaaaatca tatatcacta aagaattcac aggaaaactt ttaagttctg aaggaaaaca
    21901 atttgctatt actgaattgg aacatccatt atttgacaag attaaagctg gaactgttaa
    21961 aaatataaat tttgaaaata ttgatattaa tgtgtctaat caagataata tcgcgacaat
    22021 tgcgaatgaa atcaacggaa ccacacgtat agaaaacatc aaagcaactg gaacgataac
    22081 agccagaaat aacgttgctg gatttgtaaa caatatcaaa gaaaatgctg ctctagaaaa
    22141 cgtagcattt ataggtaata tcaattctgt tggtaataat tctacagtcg gaggaattgc
    22201 tggttcgaac tacatgggat ttgttaataa agcttatgtt gatgctaaca ttactgccgc
    22261 taacgcaagc gcaagtatgc tagttccttt ggttacatat atgttaaata gctatcagta
    22321 tggaactaag tcaaaagtta ccaattcggt tgctaaagga actttagatg ttaaaaatac
    22381 tcgttttgtt ggtggtgttg tagctaaaac ttggccttgg ggagttataa aagatattgt
    22441 tacctatgct aaagtaatta aaggtgaaga agtatatggt tcaaacgaaa ttaatgacgg
    22501 agatgcacgc caattcttat ctgatattta tagagtcaac ggcgctagca gtggagctaa
    22561 taattttacc aatctgcaaa aaataaaaca attaactaaa gaacaagctg atgctaaagt
    22621 tgctactttc aatattactg ctgataaatt agaaagtgag ctatctcctc ttgcaaaact
    22681 taatgaagaa aaagcttatt ctagtattca agattacaac gctgaatata atcaagccta
    22741 taaaaacctt gaaaaattaa taccattcta caataaagat tatattgtat accaaggtaa
    22801 taaattaaat aaagaacacc ctctaaatac taaagaagtc ctttctgtta cagcgatgaa
    22861 caacaatgag tttatcacaa acctagatga agctaataaa attattgttc actatgcaga
    22921 cggtacaaaa gattacttta acttatcttc tagcagtgaa ggtttaagta atgtaaaaga
    22981 atatactata actgacctag gaattaaata tacacccaat atcgtgcaaa aagataacac
    23041 tactcttgtt aatgacataa aatctatttt agaaccagta gatcttcaat ctcaaacaat
    23101 gtatcaacac ctaaatcgat taggtgacta tagagttaat gcaatcaaag atttatattt
    23161 agaagaaagc ttcacagccg ttaaaaagaa cttaacaaac ctaatcacaa aattagttca
    23221 aaatgaagaa caccagttaa atgattctcc agctgctcgt caaatgcttc gtgataaagt
    23281 cgagaaaaac aaagctgccc tattattagg tttaacatac ttaaaccgtt actacggtgt
    23341 taaattcggt gatgttaata ttaaagaatt aatgttattc aaaccagact tctatggtga
    23401 aaaagttagc gtattagaca gattaattga aatcggctct aaagagaaca acattaaagg
    23461 ttcacgtaca ttcgacgcat tcggtgaagt attagctaaa tatactaaat caggtaattt
    23521 agatgtattc ttaaattata atagacaatt attcacaaat atagataata tgaatgattg
    23581 gtttattgat gctacaaaag accatgtcta catcgcagaa cgcgcatctg aggtcgaaga
    23641 aattaaaaat gctaaatata gagcatatgc taacttaaac gtagctcagc acagaaaaat
    23701 gattttacca ttattgaata taactaaatc acacatgttt attgcctcta actacaacgc
    23761 aattgcaatt ggtagtgctg agaaattagg aaaaaaatca ttagaagaca ttaaagcatc
    23821 tgttgattat gctgctgatg ggtacagaaa ctactatgat ttttggtatc gtctagttcc
    23881 agataatgtt aaacaatatc tactaagaga tactgtgatt cctatctggg aaggttataa
    23941 tgcgccaggt ggctgggttg aaaaatacgg tcgatataat actgacaatg tatatactcc
    24001 tcttagagaa ttctttggac ctatagaaaa atattatggt tataatggaa caggagcata
    24061 tgctgcactt tatgataatc caatggatcc tcgttctgat gtaagttatg ttgctctaaa
    24121 tatgattggg gattatggta tttctgtgta tactcatgaa acaacacata taaacgatcg
    24181 taaaatctat ttgggtggtt ttggacgtcg tgaaggtact gatgctgaag catttgctca
    24241 aggtatgtta caactaccag tcccaggaag tggatttaac gaatatggtt cattaggtct
    24301 gaataccgta ttcaaaaaac ctaatgatgg taatcaatgg tacgatacag atcctaaatc
    24361 tcttacaaca cgtgatgata tcgataaata tatgcgtggt tacaatgatg ctttaatgct
    24421 tgtcgatcat ttagaggcag atgctgttat taatcaaaat aataaagagt taaatggagc
    24481 atggttcaag aaaatagata agaaattccg agatgccagc caattaaatc agtgggacga
    24541 aattcgaaat ctaacaactg aagaaaaaga taacttaaat attacatcaa ttgatagttt
    24601 aatagatcaa cagttaatga ctaatagaca aattggaaac cgtgtttata aacctgaagt
    24661 cgttagccaa tacgatcaat caccttatgt gggggttgaa atgacagccg gtatctacgg
    24721 aggtaatact agtaaaggtg ctcctggagc tgtttcattc aaacataacg cctttagatt
    24781 atggggttac tacggatacc ttaacggatt cctaggctat acttcgaata aatataaaca
    24841 acaatctaca aaagatggcg agtcagttct aagtgatgaa tatattatca agaaaatatc
    24901 taataataca ttcaacacta ttgaagaatt taaaaaagct tatttcaaag aagttaaaga
    24961 taaagcaacg aaaggattaa caacattcga agtaaatggt tcttccgttt catcatacga
    25021 tgatttactt acactattta aagaagctgt taaaaaagat gctgaaactc ttaaacaaga
    25081 agcaaacggt cacaaaacag tatctatgac taatacagta aaactaaaag aagctgttta
    25141 taagaaactt cttcaacaaa cagatagctt taaaacttct atctttagat aatcgaaatc
    25201 tctcatctgc tttgcggatg agggttttct tattttatgc tatacttaag gtatgcatag
    25261 aaaaacagtg attgatttta ggactttagg ggagagatat acctttaccc agcctattaa
    25321 agagttgaaa acgagaaatg tagaagaagt ggcagatttg ctggcacaag tggaaagcta
    25381 ccaagagcaa ggttattatg tggtggggta tgtcagctac gaggctgcac ctgcttttga
    25441 ggaaaaatta gcagttcaca aggatcccct actgggagag tacctgcttt attttactgt
    25501 tcatgatagc gtagaaactt cccctattcc tctgacttat gaggatattg atttgccctc
    25561 aaattggcag gaagtaacgt ctgcagcaga ctatgaaaag gccattgccc agatacacca
    25621 tcacttgagg cagggagaca cctatcaggt caactacacc gtccaactca agcaaaagtt
    25681 aagtgccaat ccttttgcca tctacaatcg tatggtggta gagcaggagg cgggctacaa
    25741 tgcctatgtg gaacatgacg agatggcagt gatttccatg agcccagagc tcttttttga
    25801 gcaaaatgat cgcgagttga caacacgacc aatgaagggg acgactcagc gtggggtaac
    25861 tgaccaagaa gatcttgaac aggccagttg gttggaacag gatcccaaaa atcgctctga
    25921 aaatatgatg attgtggacc tcttgcgcaa tgatatgaac cgtatttctg aagttgggag
    25981 cgagcacgtg gagcgtctgt gccaggtaga gcagtattca actgtttggc agatgacttc
    26041 gaccatcaag agtcagttgc gagaggatgt ggaccttgtt gaaatcttcc gctcactctt
    26101 tccttgtggt tccataacgg gtgcaccgaa aattgcgaca atggagatta tcaagaactt
    26161 ggagcctcaa ccgcgtggag tctactgtgg aacgattggt ctcttgcttc caaatggacg
    26221 acggattttt aatgtggcca ttcgtaccat tcaacttcac aaaggtcaag ccatttatgg
    26281 agttggcgga gggattactt gggatagcac atgggaatct gaataccgag aggttcatca
    26341 aaaggcagca gttctttatc gtaaacaagc tcgcttccaa ctgattacga caggggaaat
    26401 cagccagaag aacctgctgt ttgaagatca acatctggaa agactgagaa aagctagtcg
    26461 ttattttgcc tttccttttg atgcagaaga cttgggacac aagattgagg aagagtgtca
    26521 ggattgtgaa gctaatcaag attaccgctt gcgaatcagc cttagcaaat ctggagagat
    26581 agaagtcaat cgtcaagtat taacccctct cagtacaagc ttttgtcagg cccaagtctg
    26641 ccttcaggaa gctgctttga atcaatcctt tacctacttt aaaaccactc accgaccgca
    26701 tttgagccta ggagaacaag agaagattta ccacaataag tcaggagaac tgcttgaaac
    26761 ctctatagga aatttggttc tgaaaatcgc tggaaaactc tacacaccgc ctatccgact
    26821 tggaatcttg ccaggaattt accgtcagca tttgctagaa acaggacagg tagaagagaa
    26881 agtcttgacc ttggcagatt taacccaagc agaagctatt tacggctgta atgcagtgag
    26941 aggcttgtat gaactaagcc ttgaggagaa ctagatgaaa ttgatatttt tgcatgggtt
    27001 agggcagtca gcagagtctt ggaaagaagt tcggaatcta ctgacagatt atccttctga
    27061 ggctatcgag ttatttcctt ctggagttag taactatcaa caagctaaag agcgagttta
    27121 tcagcaccta gctcaagaga cagaaccttt tgttttgatt ggattgtcct taggtgctgc
    27181 cctgacacta gaactttcca gttacgattt accaaatctt cgagctttga ttctgtcagg
    27241 atgcccgctt aaattagcag ggaatatcct attttatctt cagttgctga tttttaaact
    27301 acttcccaaa agagtatttg aaaaacaggg agcagacaag actcttatgg tcggagtttc
    27361 tgaggaattg aagacacttg atttaacgga tatagcaggg acttgctcct atccaacctt
    27421 actaatttgt ggcagcaaag ataaaccgaa tcttagttct atgaaagctc tccatagact
    27481 gttaacagat tcgcagtttc agatcattcc tgatggccct catgtcttga ataaggcaaa
    27541 accaaaggag tttgtagaaa agaccagaag tttccttgaa ttgctgaaat aagtttgata
    27601 aaataatatt gaaatcgata tcataattat gggagaaaga aatgaataaa cgtctatttt
    27661 taaaaatgag tctggtgacg ttgccaattt tagccttgtt ttcacaacca gttttggcgg
    27721 aagaaaacat ccatttttcg agctgtaagg aagcttgggc gaatggctat tcggatattc
    27781 acgagggaga acctggttat tctgccaagt tagaccgtga tcatgatggt gtggcttgcg
    27841 aattgaaaaa tgctcctaag ggtgctttta aagcaaaaca gtcaacggct attcaaatca
    27901 acacaagttc agcaacaaca agtggttggg ttaagcagga cggcgcttgg tactactttg
    27961 atggaaatgg aaatctagtg aaaaatgcat ggcagggaag ctattacctg aaagctgatg
    28021 gtaaaatggc acagagtgaa tggatttatg actcttctta tcaagcttgg tattatttga
    28081 catcagatgg ttcttatgca aaaaatgcat ggcaaggagc ttattacctt aaatcaaacg
    28141 gtaaaatggc acaaggtgag tgggtttatg attcttctta ccaagcatgg tattacttga
    28201 aatcagatgg ttcatatgct cgcaatgcat ggcaaggaaa ctactatttg aaatcagatg
    28261 gtaaaatggc taaaggtgaa tgggtttatg atgccaccta tcaagcttgg tattatttga
    28321 catcagatgg ttcttatgct tacagtacat ggcaaggaaa ttactatcta aaatcggatg
    28381 gtaaaatggc tgtcaatgaa tgggttgatg gtggacgtta ttatgttggc gctgacggag
    28441 tttggaagga aggtcaagca agtacagttt cttctagtaa tgatagcaat agtgaatatt
    28501 ctgctgcttt aggaaaggca aaaagttata attcgttatt ccacatgtca aaaaaacgta
    28561 tgtatagaca attaacttct gattttgata aattttcaaa tgatgcagct caatatgcca
    28621 ttgatcattt agatgattaa cagatactgg taggcgaaaa aattccttat aattcattta
    28681 cgcaaacctt tgcataagtg aatggatttt gatatactag tactgtaagc attttcaatt
    28741 actacacaat gaaaaaggag aatatgatga gtcaaaagat tattgggatt gaccttggtg
    28801 gaacttctat caaatttgca atcttaacaa cagtaggaga aatccaagga aaatggtcaa
    28861 tcaagaccaa cattttggat gagggaagtc atatcgttga tgatatgatt gagtctattc
    28921 aacatcgttt ggacttgctt ggattggcag cagcggactt ccaaggcatt ggaatgggat
    28981 caccaggtgt ggttgaccgt gacaaaggga ctgttatcgg tgcctacaac ttgaactgga
    29041 aaacccttca accaatcaaa caaaagattg aaaaagcttt gggcattcca tttttcatcg
    29101 ataatgatgc caacgtagca gctcttggtg agcgctggat gggtgctgga gataaccaac
    29161 cagacgttgt ctttatgaca ctcggtactg gtgttggtgg tggtattgtc gcagaaggca
    29221 aattgcttca tggtgttgct ggtgcagcag gtgaacttgg tcatatcact gttgactttg
    29281 accaaccaat ctcatgtact tgtggtaaaa aaggctgcct tgagacagtt gcttcagcaa
    29341 cagggattgt caacttgact cgtcgctatg ccgatgaata cgaaggcgat gcagccttga
    29401 aacgcttgat tgataacgga gaagaagtaa ctgctaagac tgtctttgat ctcgcaaaag
    29461 aaggagacga ccttgctttg attgtttacc gtaacttctc acgttacttg ggaatcgctt
    29521 gtgctaacat tggttcaatc ctaaacccat caacaatcgt catcggtggt ggtgtgtcag
    29581 ctgcgggaga attccttcta caaggtgttc aaaaagttta cgatgaaaat agtttcccac
    29641 aagtacgcac atctactaaa ttagctcttg caactctagg aaatgacgct ggagttatcg
    29701 gagcagcatc acttgtattg caataagata atgagagagg aaaatgctaa cctagagtta
    29761 gtaatgttcc tcttttattt tttatgctat actagttagg acaatgaatg aggtgaaacg
    29821 aaatgacaaa agcagatacg atttttaaag agaatattga acgcattcta aaggaaggtg
    29881 ttttctcaga gcaggctcgt cctaagtaca aggatgggac tgttgctaat tccaagtatg
    29941 taactggtgc cttttccgag tacgacttat ctaaaggaga atttcctatc acaaccttgc
    30001 gtcccattgc aatcaaatcc gccatcaaag aagttctctg gatttaccaa gaccagtcaa
    30061 atagcttaga agtgcttaat gacaagtaca atgttcacta ctggaatgac tgggaagttg
    30121 gagacacggg aaccattggt gagcgctatg gtgccgttgt taagaaacac gacattatca
    30181 ataagcttct caaacagttg gaaaccaatc cttggaaccg ccgcaatatt atttcgctct
    30241 gggattacca agctttcgaa gaaacagatg ggctgctccc gtgcgccttt cagaccatgt
    30301 ttgatgtccg ccgtatagat ggagaaatct atctggatgc gaccttgacc cagcgctcga
    30361 atgatatgct ggtggcccac cacatcaacg ctatgcagta tgtggctttg cagatgatga
    30421 ttgccaaaca ttttggctgg aaggttggga agttcttcta cttcatcaac aacctccata
    30481 tctatgataa tcaatttgaa caagctcagg aattgctccg tcgggagccg tcaaactgcc
    30541 aaccacgctt ggttttaaat gttcctgatg ggactaattt ctttgatatc aaagcagaag
    30601 attttgagtt ggtggattat gaccctgtta agccacagtt gaagtttgac ctagctattt
    30661 aaaagaatag aaaaaagaag ttgagaataa tcccaacttc ttttgtttct taacgtgata
    30721 ctcggcgacg agctgctttt ttacggtttt cttcgatgaa agctgctttt tgctcttctg
    30781 gttcgattac tttcttttta aatgcgtata ctgcacctgc aacggcagcg acagttcctg
    30841 cgacacctgt tacaagacct ttagcgaatc ctttagccat gagtcttcct cctttatatt
    30901 ctcaatcagc cagcctcctc aagaggtcac atttttctga ctgacctttt tgtgttataa
    30961 taatagtaac gaaaaaatgg gaatttttca aggaaaaaag atgaaaacaa aaataattgt
    31021 gattgttgga ccgactgctg ttggaaagac ggctctagct attgaagttg caaagcgttt
    31081 taatggcgaa gtggttagtg gagatagcca acaagtctat cgaggacttg atattgggac
    31141 agctaaggct agtccagaag agcaggcagc tgttcttcat catttaatcg atgttagaga
    31201 gataaccgag tcttactcgg cttttgattt tgtttcagaa gctaagatga ctattgagga
    31261 tattcacagc cgtggcaagc tagccattat cgccggtggg actggacttt atatccagag
    31321 cttgctagaa ggttaccacc taggtgggga gactcctcat gaggagattt tagcttatcg
    31381 agctagtttg gagccgtatt cagatgagga attagcccat tttgtggagc aagcaggcct
    31441 tgagattccc cagtttaatc gtcgtcgtgc tatgcgtgcc ttagaaattg cccattttgg
    31501 tcaggatttg gaaaatcaag agaccttgta tgaaccgctg attatctgct tggatgatga
    31561 acgtagtcaa ctttatgagc gtatcaacca ccgagtggat ttgatgtttg aggctgggct
    31621 tttggatgag gccaagtggc tgtttgacca ttcccctaat gtacaggctg ctaaaggaat
    31681 tggctataag gaactctttc cttatttccg tggagagcag acctttgagg aagctagtga
    31741 gagtcttaaa caggcgaccc gtcgttttgc caagcgtcag ctgacctggt tccgtaatcg
    31801 catgcaggtc accttttatc agattggaga atctggtgta caagaccgca ttttaagcca
    31861 gatagaggag tttttagatg attgaaacgg agaaaaaaga ggagcgagtc ctgctgattg
    31921 gtgtggaatt gcagggtatg gacagttttg acctctccat ggaagaattg gctagtttag
    31981 cgaaaacggc aggggcagtc gttgtagata gctacagaca aaaacgtgaa aaatatgatt
    32041 ccaagacctt cgtcggctct ggtaagttgg aagagattgc gcttatggtg gatgcagaag
    32101 aaatcactac tgtcatcgtc aacaaccgtc tgaccccaag gcagaatgtc aatctagagg
    32161 aagttctcgg tgttaaggtc attgaccgta tgcagttgat tttggatatc tttgccatgc
    32221 gggctcgaag ccatgaaggg aagttccaag tccacctagc ccaactcaaa taccttttgc
    32281 ctcgcttggt tggtcagggg attatgctca gccgtcaggc agggggaatt ggttcccgtg
    32341 gtcctggtga aagccagctg gagctgaacc gtcgtagcgt tcgcaatcaa atcacggata
    32401 tcgagcgcca gctcaaggtg gttgagaaaa atcgtgcgac tgtcagagaa aaacgtttgg
    32461 agtctagcac ttttaagatt ggtttgattg gttataccaa tgctgggaaa tcaactatca
    32521 tgaacatctt gaccagtaag acccagtatg aagcagatga gctctttgcg actctggatg
    32581 cgacaaccaa gagtattcat ctgggaggca atctccaagt aactttgaca gataccgttg
    32641 gctttatcca agatttgccg acagagttgg tgtccagttt caagtcaacc ttggaagaaa
    32701 gcaagcatgt ggaccttctg gttcatgtta tcgatgctag caatccttac cacgaggagc
    32761 atgaaaaaac ggttctctcc atcatgaaag acctggacat ggaagatatt cctcacttga
    32821 cgctttataa taaagcggat ttggtggagg atttcacgcc tacccaaacg ccatataccc
    32881 tcatttctgc caagtctgag gacagtcgtg aaaacttgca agcattattg ctagataaga
    32941 ttaaggaaat ttttgaagca tttaccctgc gagtgccttt ttcaaagtcc tacaagattc
    33001 atgatttaga gagtgttgca attctggaag aacgtgatta tcaggaagac agcgaagtga
    33061 ttacaggcta catttccgaa aaaaataaat ggaggttaga agaattttat gactgatatt
    33121 aaagctttgg ctctaaagta tggaggttat acaagtctgg acaaggtcta tctggttcag
    33181 cttctagctg gtaaaacaga gcaggagcag ttaacactta ttacacctcc gccaagtgtt
    33241 gttaatgcct actttgcaga actctatcag aaaaagagtc ctcaggctgc gacggattat
    33301 tttgcagaac tcagtcagga actgaatctt tacaatactg agccaagttt caccctagaa
    33361 aataagcctt ttattcggct taatctgtct ggtaaatcct ttggtttttg ttatgatagt
    33421 gacggccttg gtcggatttt ctctgaaaat gaggagaaaa tctcggatga cttgctcttt
    33481 gaaattgcgc aaattttccc ccatcaatta gtctttgaag agtctggtaa gatttacatg
    33541 aagcctgtcg aggacgagga agttgtcagc ctagaaagtc tcacagcttt gactgatttg
    33601 gaaagattgg ctgatggtcg aaaacgtctc aaaggctaca gccaagagga tttattgcaa
    33661 gaagctgctg ctttttctgg caaacgctat ttccgatcgg aaaaccgcac agccatgtta
    33721 tatattgatt aattagaaag tatcgaatgg atattcaatt tttaggaacg ggggctggtc
    33781 agccctctaa agctcgcaac gtttcaagtc tcgccctgaa acttttggat gagattaacg
    33841 aagtttggct ctttgactgt ggagaaggta cgcaaaatcg cattctggaa accacagttc
    33901 gaccacgtaa gatcagcaaa atctttatta cccatctgca tggagaccac atttttggtt
    33961 tgccaggttt cctttctagc cgtgcctttc aggccaatga agagcagaca gatttggaaa
    34021 tctacggacc tcaaggaatc aagtcatttg tcttaaccag ccttcgtgtg tcaggttctc
    34081 gtctgcccta ccgcattcat ttccatgagt ttgaccaaga ttctctagga aaaatccttg
    34141 agaccgataa attcactgtg tatgcagagg agctggacca tactattttc tgtgttggct
    34201 atcgtgtcat gcaaaaggat ctagaaggga cgctggatgc tgaaaaactc aaggctgctg
    34261 gtgttccgtt cggcccgctt tttggtaaaa tcaaaaacgg ccaggatctt gttttggaag
    34321 acggaactga aatcaaggcg gctgactata tctcagcgcc acgtccaggt aagattatca
    34381 ctattttagg agacactaga aaaaccaatg ctagtgtgcg tctggctgtc aatgcagatg
    34441 tcctagttca tgagtccact tatggcaagg gtgatgaaaa aattgctcgt aaccatggtc
    34501 actcaactaa tatgcaagct gcacaagtag cggtagaagc aggtgccaaa cgcctcctac
    34561 tcaaccatat cagtgcccgt ttcctctcaa aagatattag caaactcaag aaagacgctg
    34621 ccacaatttt tgaaaatgtc catgtggtca aagacttgga agaagtggaa atctagcagt
    34681 cacagaaagg ataagtatgc ctactattct cattaccgga gctagcggtg gtctagctca
    34741 agaaatggtc aaactcctgc ccaatgacca actcatcttg cttggtagaa ataaggaaaa
    34801 attagcccaa ctctacggaa attattccca tgcagaattg attgaaattg atattaccga
    34861 cgattcagcc ctagaagctc tggtaactga tctttatctc cgctatggca agattgatgt
    34921 cttgattaac aacgctggtt acgggatttt tgagggattt gaccagattg ctgataaaga
    34981 cattcaccag atgtttgagg tcaatacctt tgccctgatg aatctgtctc gtcaccttgc
    35041 ggctcgtatg aaggaaagca gcaaagggca tatcatcaac atcgtcagca tggcaggtct
    35101 aatagctact ggcaagtcta gtctttactc agcgaccaag tttgcggcta ttggtttttc
    35161 aaatgctctg cgactcgaac ttatgcccta tggagtctat gtgacaacag tcaatccagg
    35221 tccaatccga acaggatttt ttgaccaagc tgacccagat ggaacttatc ttaaatcggt
    35281 tgaccgcttc ctcttagagg cagatgcagt ggctaaaaag attgtcaaga ttataggaaa
    35341 aaataaacga gaactcaatc tcccgatttt gttgaaccta gcccataagt tttatactct
    35401 ctttcccaag ctagctgata agttggcagg ggaaactttt aattataagt aaaaagaacc
    35461 aatgtgcagg ttgttgctag cctacatatt ggttcttatc atttctcaac tatcaaactg
    35521 aacttcttct agtagatagt cgataaagcg ttcgcccatc ttagataggc tggttttctc
    35581 atgctggata tagaccagct caatcgggtc atcaatatcc agtgggatag aaacgatatt
    35641 gtctccgttt aggttgctgt tcaaaatccc tgtcgcaatg gtataaccat ccaaaccaat
    35701 caagagatta aagagggtgg cacggtcact gaccacaatg gatttcttgt ggtgttcttg
    35761 agaaagaatc tcttctgaaa agtagaagga gttgtgcgtc ccttggtcat agctgaggta
    35821 agggaaattc tccaaatcag acagtttcac cttgtctttc tttgccagag ggttggtctt
    35881 gctgacaaag atatgcggtt gcgctgtgaa gagatggtgg gatagcaggt gattgtcatc
    35941 cagcatcttg gttaaaacat cacggttgta actgtttaag aagaggaccc cgacctcact
    36001 gcggaagttc ttgacgtcgt cgataatctc ccaagtccga gtttcacgaa ggaagagttc
    36061 gtatttctcc atatcgcttt tcttgagcaa agagacaaag gcattgacca caaaggcata
    36121 gtgttgagac gaaacgctaa agagttcgcg gtgggcgaca ggatttttat agcgttcctc
    36181 cagaagctga gtttgctcga caacctgacg ggcataagag agaaactcca tcccatcacg
    36241 ggtcaaggta atacccttgg gattgcggat aaagatttca atgcccattt cattttccaa
    36301 atctcgcact gcattggaga gactgggctg agtgataaag agttgcttgg ctgcctcatt
    36361 catagagcca gtttcgacga ttttgataat ataatgtaat tgttgaattc tcatgttttt
    36421 attgtaccac acttgcctta gaatcgccaa agaagatagg aaaataagga gcattgtgtg
    36481 agtctcttct tgaaaaaaac acaaaatttt gctagaatga gtcttatgaa aacattctat
    36541 gatgtgcagc aattcctcaa acgatttggt attattgttt acatgggaaa acgcttatat
    36601 gatattgaac tgatgaagtt ggaactatct cggatttacg atgcagggtt gatggataaa
    36661 ttagactatc tagaggcaga agcagttctt cgcagagagc acaaggtaga attggattat
    36721 attgagaaaa atggagaaaa gaactaatgg ttacttggat tttgtgggca cttatactag
    36781 caatgttggc gtggatgggc tttaactatc ttcgtattcg ccgtgcggct aaaattgtgg
    36841 acaatgagga gtttgaagcc ttgattcgta cgggtcaatt gattgatttg cgcgacccag
    36901 cagaattcca cagaaaacat atccttcgtg cacgcaatat tccttcaagt cagttgaaaa
    36961 ctagtcttgc agcccttcgt aaagataaac ctgtccttct ctacgagaac caacgtgcgc
    37021 aacgagttac aaatgcagct ctttacttga aaaaacaagg tttttctgag atttatatcc
    37081 tttcttatgg cttggattct tggaaaggga aagtgaagac tagctaacct tatttccaaa
    37141 ttagtcgaat gataggatga agctattgtt ttatagtata attaatttgt ataaaattta
    37201 aagagttctt agaacatgaa agaaaagaag aaaaatccac tttttgtggg tatcttgtcg
    37261 attattcttg gtttgttatt tccaattgta ggcctgattt tgggtatcat aggattggtc
    37321 ttggctattt cataccaaaa agagtcacaa ttagagtata aaatagaaaa gattcttaat
    37381 atcttaggaa ttgtgatttc tgtagttaac tggattgtag caatcgcctt aatttttcgg
    37441 taaataaaag aaaaaagctt tagttttaaa gctttttttg ttttatcgac tcatctctaa
    37501 atagttttta atgatttgta actctttttg gttcaaaggg cggtagttac cttctgctaa
    37561 atctgggttc aatgtgaagt ccccaaattg gattcttttg aggctagtca ccttaacacc
    37621 aaccgagagg aacattttct tgatttgatg aaattttcct tctgaaatgg tgatagaggc
    37681 ttgactgagg gagggacttg cagatagaat ctctagtttt gcgggtttac agacagtacc
    37741 atctaaaaag acaattccct tttgaaaggc ttggatatgg tcaggtgtta gaagtccatt
    37801 aacctcaact tgataagtct tatcgacatg atattgggga tggaggagtt ggaagcccaa
    37861 gggaccgtta tcggtcaaga gaaggagtcc tgttgtatct cggtccagtc ggccgacggc
    37921 atagagcttg tcagactgga tgtcagatgg aagcaagtcc atgacggtcg gaagttcctt
    37981 gtctttgttg gctgtaacga caccagcagg tttatgaagc ataagatagg tgtgttcata
    38041 gccttgaatg attcgatcct gaaaaaggag ttcttgtagt cctgtatcga tattttgagc
    38101 tagggagcgg gctgggcaac catcgactag aatttcccct ctgaggagtg cttgcttcat
    38161 ggcctttcgg ctaacttttt cttgggctaa taaattatct aaacgcatac tgtgcctatc
    38221 ttatcataag tcgcttgctt tgaaaaggct tgacgtgaaa agaaaagcgg agtgaaaaca
    38281 tttacacttg cttgagttat gttatttatt tgaaattatg gtataatcgt tcagttagaa
    38341 aataaatttt gaatattata gaggaaatca tgacaaaatt aagagaagat atccgtaaca
    38401 ttgcgattat cgcccacgtt gaccacggta aaacaaccct ggttgacgaa ttattgaaac
    38461 aatcagaaac gcttgatgca cgtactgaat tggcagagcg tgctatggac tcaaacgata
    38521 tcgaaaaaga gcgtgggatt accatccttg ctaaaaatac tgccgttgct tacaacggaa
    38581 ctcgtatcaa cattatggac acaccaggac acgcggactt tggtggagaa gttgagcgta
    38641 tcatgaaaat ggttgacggt gttgtcttgg tcgtagatgc ctatgaagga accatgccac
    38701 aaactcgttt cgtattgaaa aaagccttgg aacaagacct tgtcccaatc gtggttgtta
    38761 acaaaatcga taagccatca gctcgtccag cagaagtagt ggatgaagtc ttggaacttt
    38821 tcatcgagct tggtgcagat gacgaccagc ttgatttccc agtggtttat gcttcagcga
    38881 tcaacggaac ttcttcattg tcagatgatc cagctgacca agaagcgact atggcaccaa
    38941 tctttgacac gattatcgac catatcccag ctccagtaga taactcagat gagcctttgc
    39001 agttccaagt gtcacttttg gactacaatg acttcgttgg acgtatcggt atcggtcgtg
    39061 tcttccgtgg tacagttaag gttggggacc aagttaccct ttctaaactt gacggtacaa
    39121 ctaaaaactt ccgtgttaca aaactcttcg gtttctttgg tttggaacgt cgtgaaatcc
    39181 aagaagccaa agcgggtgac ttgattgccg tttcaggtat ggaagacatc tttgtcggtg
    39241 aaaccatcac tccgacagat gcagtagaag ctcttccaat cctacacatc gatgagccaa
    39301 ctcttcaaat gactttcttg gtcaacaact caccatttgc tggtaaagaa ggtaaatggg
    39361 taacttctcg taaggtggaa gaacgcttgc aggcagaatt gcaaacagac gtttcccttc
    39421 gtgttgaccc aactgattca ccagataaat ggactgtttc aggacgtgga gaattgcact
    39481 tgtcaatcct tatcgaaaca atgcgtcgtg agggctatga acttcaagta tctcgtccag
    39541 aagttatcgt aaaagaaatc gacggtgtta aatgtgaacc atttgaacgt gtacaaatcg
    39601 acactccaga agaataccaa gggtctgtta tccaaagcct ttctgaacgt aaaggtgaaa
    39661 tgttggatat gatttcaact ggtaatggtc aaactcgttt ggtcttcctt gttccagcgc
    39721 gtggtttgat tggatactca actgagttct tatcaatgac tcgtggttac ggtatcatga
    39781 accatacctt cgaccaatac ttgccattga ttccagggga aattggtgga cgtcaccgtg
    39841 gtgcccttgt ttctatcgat gctggtaagg ctacaactta ctcaatcatg tctatcgaag
    39901 aacgtggtac gatctttgtc aacccaggta ctgaggttta tgaaggaatg atcatcggtg
    39961 aaaactctcg tgaaaatgac ttgacagtta acatcacgaa ggcaaaacaa atgaccaacg
    40021 ttcgttcagc tactaaggac caaacagctg ttatcaagac gcctcgtatc ttgacacttg
    40081 aagagtctct tgagttcttg aacgacgatg agtacatgga agtaacgcct gagtctatcc
    40141 gtttgcgtaa acaaatcctt aacaaagcag agcgtgagaa agctaacaag aagaaaaaat
    40201 cagctgaata agagctagaa agagagaaag atggtctatt tagtcctagg aattttactg
    40261 ctcctactct atgtatttgc gacaccagaa agcattaaag ggactgtcaa tatcgtcgct
    40321 atggtatgta ttttagtggc actcttgatt ttattggttc tatcttttct gaaaattttt
    40381 caattaccaa cagaaatatt cctagcaata gccatgttga tcctagctta ctttagtgtt
    40441 agagacatca cactcatgcc agtcaaaaaa agtaaaagaa gataaaaaag agagtttcgg
    40501 ctctcttttt gctaggaatt ttacaatagt ttgaattgct ttttagttaa caccatctct
    40561 tttacttgta tagtatgaat gggaaaaact tgaataaaat tcgttaatgg catctatttt
    40621 atatttggtt agtactggtt gcatattatt ttgaaataaa actactatat aatattattc
    40681 acagaggtaa tatagtaaaa tatctaaaaa attcgatttt ttccttgaca acaaataata
    40741 aaaaagttat tcttatcaca taagaaagcg gtttcaataa aagagagagg aggatttatt
    40801 ttgttgcatt gttgctcaag gtgtgctttt tttgaaagaa aaaataaaat gaaaacgaaa
    40861 aaacatagat tacttgctct agctcttatt tcaaatttta cattattggg agctgcatca
    40921 gctgctgtac aatatccaga tggaggagta tggacatatg gagaaggttc aggaggtggt
    40981 taggcttttt caaattacta tcatggtaaa aaatatcatt attcatccat cgtgagcaga
    41041 tgggatggtc attctgataa aggagaagct cctgctggaa aaacctccta tgcatggatt
    41101 tggactaaat ggggagaaca agtagcattt tactgtgatt atgactaatc gttcattgat
    41161 ttaaatcgtt ccccttgtaa gaaattacag ggggaatttt gtttacaagg agtctactat
    41221 gaagaaacta ttcatattat tatcaacttt ttttctcagc ttcttccttg cttggattat
    41281 tgtcttacgt gcgccacaat atttatatgc aagctatgat tccgtttctt tacttcgtgt
    41341 caaaaaagat actcaggaac cgacgcgtga ggtatttgaa caggaattgg agaattttgc
    41401 aaactcagaa cagagtttaa tagctagaag aattgtagag ccgagtaagg atgggacgac
    41461 tcactttact tatgcaactt atggtcaggg aactttacca aaagaattcc aagaagctag
    41521 ccaagaaagt cgtgaacgta gtgatccgct aaatagttat ctccttttgt caggctcctt
    41581 gacgaaagaa aagcttgccg ataaattagg agatttgggt tataaagcaa gtgctgaccg
    41641 aaagataccg ccctattttc ttgcttttcg aatattacta aatcccctta ttttaattag
    41701 tttagcaata tttggcttat ctttctttgc tttagtgatt atcactcgga ttaaggaaat
    41761 gagagcagca ggtataaaac tcttttctgg tcagactctc ttatccatca tggggcattc
    41821 tttatctact gatatcaaat ggctccttct atcagccctc ctttccttcc taggtggggg
    41881 agtcgttctt tttagtcaag gtttgtttta tcctatcttg ttagccacct atggttttgg
    41941 gattagtttc tatctgttgt ttttattggc gatttcaatt ttactaatgc ttctttatct
    42001 aatgagtttg aattacaaag cattagttcc cgttattaag gggagattac cccttaaacg
    42061 cctgatgatt ttaaccctat tgtgtcagtt ggttgctgtc tttacagtag gatacgctgt
    42121 taagacaggt ttgacgtctt accaacgatt gaaagaactt gaaatttcaa aacaagcatg
    42181 gcaggataga gcagactatt atcaaatttc ttttggctta ggtgatagag gaaaagatac
    42241 agaaaatcag agcaagtggt atgcctttgc caaggaagca atcgaagaag aacaagctct
    42301 ttatgtaaag gataatctgc tccattttgc caatccacaa ggaaaaaatg aacagggaga
    42361 gacactggat acctatagtc cagatgctaa tacgctctat gttagtccca gttatttgga
    42421 caaggaaaag gtcgtggtag atgctgagac caaacagaag ttagcccatc tccaaaaagg
    42481 tgagtttatc ctcttgctcc cagaacattt gcgctctcga gaagcagaac ttaagaaagt
    42541 ttttgaagaa agattgagtt attatggaaa atctggtgag gaggcaagtg ctcctttgga
    42601 ttatgagatg aaagcgcacg ttagttatct ttcaatggga gaaaagcggt ttgtttataa
    42661 taacggtgag aatcccgtat ccactcagta tttgactgat ccgattttag tggtattcac
    42721 gccgacttct acaggtgata gttttatatc cctatctagt tggtctatca atgctggaaa
    42781 acaactcttt atcaaaggat atgagagtgg gctagaactt ttgaagaaag ctggaattta
    42841 tgagcaagta tcctatctta aagaaggaag aagtgtttat ctaactcgtt ataatgaagt
    42901 tcaaactgaa acagcaactt taatcttagg agctattgtg gggatagcta gttccttgtt
    42961 actattttat tctgtcaatc ttctatattt cgagcaattc cgccgagata tcttgattaa
    43021 acgaatttca ggtttacgat tttttgaaac acatgctcag tatatggtta gtcaatttgc
    43081 cagttttgta tttggtgcta gtctttttat tttaagcagt cgagacttgg tgattggctt
    43141 gctcacttta ttagtctttc tagctagtgc agttctgacg ctttaccgtc aagcgcagaa
    43201 agaatctcgt gtttctatga caattatgaa aggaaaatag gatgattgaa ctaaagaata
    43261 tatctaaaaa atttggaagc cgtcagctat tttcagatac gaatcttcat tttgaaggtg
    43321 ggaaaattta tgccttaatc ggtacaagtg gctgtggtaa gacaacactc ttgaatatga
    43381 ttggacgatt agagccatat gacaaagggc aaatcatcta tgatggcact tctcttaagg
    43441 acatcaagcc ttctgttttc tttagagatt acttaggata cttatttcaa gattttggct
    43501 taattgaaag ccaaaccgtc aaagagaatc tcaatctggg tttagttggt aaaaagttga
    43561 aggaaaaaga gaaaatctct ttgatgaaac aagctctaaa ccgtgtaaac ctctcttatt
    43621 tggatttgaa gcaacctata tttgagttat caggaggaga agcacaacgt gttgcattag
    43681 cgaagataat tttaaaggat ccacctttga tcctcgcaga tgaaccaacc gcttccttag
    43741 accccaaaaa ctctgaggaa ttactttcca tcctagaatc tttaaaaaat ccgaatcgaa
    43801 ctattattat tgcgacccac aatcctctta tttgggaaca agtggaccaa gttattcgag
    43861 ttaccgattt atcacataga tgatatggca agattcagct agaagaaaga gtcacaaaca
    43921 cactttgtgg cttttttatt tccataaaaa tggtaaaata gtaggagtag aaatggagtt
    43981 cgagacatga aagtaataga tcaatttaaa aataagaaag tccttgtttt aggtttggcc
    44041 aagtctggtg aatctgcagc tcgtttgttg gacaagctag gtgccattgt gacagtaaat
    44101 gatgggaagc ctttcgagga caatccagct gcccaaagtt tgctggaaga agggatcaag
    44161 gtcattacag gtggccatcc tttggaactc ttggatgaag agtttgctct tatggtgaaa
    44221 aatccaggta tcccctacaa caatcccatg attgaaaagg ctttggccaa gggaattcca
    44281 gtcttgactg aggtggaatt ggcttatttg atttcagaag caccgattat tggtatcaca
    44341 ggatcgaacg gtaagacaac cacaacgact atgattgggg aagttttgac tgctgctggg
    44401 caacatggtc ttttatcagg gaatatcggc tatccagcta gtcaggttgc tcaaatagcg
    44461 acagacaaga acacgcttgt tatggaactt tcttctttcc aactcatggg tgttcaagaa
    44521 ttccatcctg agattgcggt tattactaac cttatgccaa ctcatatcga ttatcatgga
    44581 ttatttgagg aatatgtagc agccaagtgg aatatccaga acaagatgac agcagctgat
    44641 ttccttgtct tgaactttaa tcaagacttg gcaaaagact tggcttccaa gacagaagcc
    44701 actgttgtac cattttcaac acttgaaaag gttgatggag cttatctgga agatggtcaa
    44761 ctctacttcc gtggtgaagt agtcatggca gcgaatgaaa tcggtgttcc aggtagccac
    44821 aatgtggaaa atgcccttgc gactattgct gtagccaagc ttcgtgatgt ggacaatcaa
    44881 accatcaagg aaactctttc agccttcggt ggtgtcaaac accgtctcca gtttgtggat
    44941 gacatcaagg gtgttaaatt ctataacgac agtaaatcaa ctaatatctt ggctactcaa
    45001 aaagccttat caggatttga caacagcaag gtcgtcttga ttgcaggtgg tttggaccgt
    45061 ggcaatgagt ttgacgaatt ggtgccagac attactggac tcaagaagat ggtcatcctg
    45121 ggtcaatctg cagaacgtgt caaacgggca gcagacaagg ctggtgtcgc ttatgtggag
    45181 gcgacagata ttgcagatgc gacccgtaag gcctatgaac ttgcgactca aggagatgtg
    45241 gttcttctta gtcctgccaa tgccagctgg gatatgtatg ctaactttga agtacgtggc
    45301 gacctcttta tcgacacagt agcggagtta aaagaataaa atatgaaaaa aattgtcttt
    45361 acaggtgggg ggacggttgg acacgttacc ctcaatcttt tgttaatgcc caagttcatc
    45421 gaagatggtt gggaagtcca ctatatcggg gacaagcgtg gtatcgaaca ccaagaaatc
    45481 cttaagtcag gtttggatgt caccttccat tctattgcga ctgggaaatt gcgtcgctat
    45541 ttctcttggc aaaatatgct ggacgtcttc aaagttggct ggggaatcgt ccaatcgctc
    45601 tttatcatgt tgcgacttcg tccacagacc cttttttcaa agggaggctt tgtctcagta
    45661 ccgcctgtta tcgctgcgcg tgtgtcagga gtgcctgtct ttattcacga atctgacctg
    45721 tctatgggct tggccaataa aatcgcctat aaatttgcga ctaagatgta ttcaaccttt
    45781 gaacaagctt cgagtttggc taaggtcgag catgtgggag cggtgaccaa ggtttcggat
    45841 caaaaaaatc cagaaccaga tgaattggtg gatattcaaa gccactttaa tcataaattg
    45901 ccgactgtat tgtttgttgg cggttctgca ggtgctcgtg tctttaacca attggtgaca
    45961 gaccataaga aagaactaac agagcgctac aatattatca atctaactgg agattctagc
    46021 ctgaatgagt tgagccaaaa tctttttcgt gttgactatg tgaccgatct ctatcaaccc
    46081 ttgatggaat tggctgatat tgttgtgaca cgtggtggtg ccaatacgat ttttgagctc
    46141 ttggcgatag caaaattgca tgtcattgtg ccacttggtc gtgaagctag tcgtggtgac
    46201 cagattgaaa atgcagctta ctttgttaag aaaggctatg cagaagacct tcaagaaagc
    46261 gatttgacct tggatagttt ggaagagaag ctttctcact tactaagtca caaggaagat
    46321 taccaagcta agatgaaagc ttctaaggaa ttgaaatctc tagcagattt ttatcaattg
    46381 ttgaaaaaag atttatcata aggaaagtaa atgtcaaaag ataagaaaaa tgaggacaaa
    46441 gaaatcctcg aagaattgaa agagttatca gaatggcaga aacgaaacca agaatatcta
    46501 aaaaagaagg ctgaagaaga agcggctcta gctgaggaga aggaaaagga aagacaagct
    46561 cggatgggag aagaatctga gaagtcagag gacaaacagg accaggagag tgaaacagac
    46621 caggaagatt cagaatcagc taaggaagag tctgaagaaa aagtagcatc ctcagaggct
    46681 gacaaagaga aagaagagaa agaagaatca gagtctaaag agaaggagga acaggataaa
    46741 aagcttgcta aaaaggctac aaaggaaaaa ccagccaaag caaagattcc tggtatccat
    46801 atcttgcgag ccttcacgat tttatttcca agtctgcttt tattgattgt ctctgcctac
    46861 ttgctcagtc cttatgcgac catgaaagat attcgtgttg agggaacggt gcaaactaca
    46921 gctgatgata ttcgacaggc ttcaggcatt caggattcgg attatacgat taaccttctg
    46981 ctagacaagg caaaatatga aaagcagatt aagtctaact attgggttga atcagctcaa
    47041 cttgtctatc aatttccaac taagttcact attaaggtca aggaatatga tattgtggcc
    47101 tactatattt ctggtgaaaa tcattatcct attctttcca gtggtcagct tgagactagt
    47161 tctgtgagtc tgaacagttt accagaaact tatttatcag ttctctttaa tgatagtgaa
    47221 caaatcaagg tttttgtctc agaacttgct caaattagcc cagaactcaa ggcggctatc
    47281 caaaaggtgg aattagcccc aagcaaggtg acatccgatt taattcgatt gaccatgaat
    47341 gattcggacg aagtcttggt tcctctatct gaaatgagta agaaactgcc atattacagt
    47401 aagattaagc cacaattgtc agaaccgagt gtggtcgaca tggaagctgg aatttacagt
    47461 tacactgtgg cggataaatt aattatggag gctgaggaaa aagccaaaca agaggccaag
    47521 gaagctgaga aaaaacaaga agaagaacag aaaaaacaag aggaagagag caatcgaaat
    47581 caaacaaatc agcgttcatc gcgtcgctag gtttaccttt tctcttatag ttctttagtg
    47641 accatgtttt tacgtttaat atttgacatt tgtttttctt tatgttacat ctgcaatgta
    47701 atcgattaca aaataatttt tgatgaagaa ggtaacacat atgtcagatg aagtattctt
    47761 atttgaagaa attgaagaaa tcgtagcccc tacagatggt gaatttttgg gggaagtttt
    47821 acttggaact ggggtagttc tcttaattgg agtagcctgt tgttaaaaag atagggagtg
    47881 ataatcatgc aagataactt tttatttgag gaaattgaag aaatttcagt accagttagt
    47941 gatttttcag ctggacttgc aacaggtatc ggatttggtt tagcaatcct tgctcttgct
    48001 ggttgttgaa gtttgttcat ttactaacat caagcttttt caatttcatt ttagacagtc
    48061 atttgaattt tccgtattag tcttgcagca agagattaat agaattagtc attattttat
    48121 tgattgcgga ctgagggact agagtatgtt ttacttagcc cctcttttat ttattaaagg
    48181 ttaggtttgt tatgagaatt gttgataaga ttaagatatt acctactcct tatgagggac
    48241 agtatcatct atatatacca tccagtaaga aacatgtatt agttgggaaa caggaaaaaa
    48301 atggttagag caactaatag gtcaagaatt taccatatcg gacttattag tgttagtagg
    48361 gaagaaatat tatttaagat tttatattgt tcttagtaaa atgggactta tagattctat
    48421 gaaatcacga aaaaagataa atatt
//
LOCUS       DBEJKC010000007        48237 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.007, whole genome shotgun sequence.
ACCESSION   DBEJKC010000007 DBEJKC010000000
VERSION     DBEJKC010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 48237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48237
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.007"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(1..410)
                     /locus_tag="ACL3G6_000413"
                     /pseudo
     CDS             complement(1..410)
                     /locus_tag="ACL3G6_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
     gene            complement(412..1449)
                     /locus_tag="ACL3G6_000414"
     CDS             complement(412..1449)
                     /locus_tag="ACL3G6_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HGR0545000.1"
                     /translation="MNQTINYIKELTAIASPTGFTREISDYLVHTLEKLGYQPVRTAK
                     GGVNVTIKGQNDEQQRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQTVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDAKVTNEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRVYKEEGIELPVTTHFAFSVFEE
                     VGHGANSNIPTQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLRSNLVD"
     gene            complement(1547..2872)
                     /gene="brnQ"
                     /locus_tag="ACL3G6_000415"
     CDS             complement(1547..2872)
                     /gene="brnQ"
                     /locus_tag="ACL3G6_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGR0545001.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAVAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(3043..3330)
                     /locus_tag="ACL3G6_000416"
                     /pseudo
     CDS             complement(3043..3330)
                     /locus_tag="ACL3G6_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658232.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(3490..4068)
                     /locus_tag="ACL3G6_000417"
     CDS             complement(3490..4068)
                     /locus_tag="ACL3G6_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HGR0545002.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFVAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     DFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMSKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(4122..5522)
                     /gene="pepV"
                     /locus_tag="ACL3G6_000418"
     CDS             complement(4122..5522)
                     /gene="pepV"
                     /locus_tag="ACL3G6_000418"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HGR0545003.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFDFAGPAKEYLDITGKILLNDHEGESLKIAHVDEKMGALSMNAGV
                     FRFDETCADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLQGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(5535..6140)
                     /locus_tag="ACL3G6_000419"
     CDS             complement(5535..6140)
                     /locus_tag="ACL3G6_000419"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGR0545004.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVCEKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            6311..7111
                     /locus_tag="ACL3G6_000420"
     CDS             6311..7111
                     /locus_tag="ACL3G6_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0545005.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKESSSQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTYLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSTDSPSN
                     YIVFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(7289..8122)
                     /locus_tag="ACL3G6_000421"
     CDS             complement(7289..8122)
                     /locus_tag="ACL3G6_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR0545006.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLQGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEVLDGEYGLEYPKEIQSMRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSKGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRREDNYQRHNLKLLASLIEKHRYVEDVKNFFDF
                     L"
     gene            complement(8112..9956)
                     /gene="uvrC"
                     /locus_tag="ACL3G6_000422"
     CDS             complement(8112..9956)
                     /gene="uvrC"
                     /locus_tag="ACL3G6_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HGR0545007.1"
                     /translation="MNNLIKPKLELLPTSPGCYIYKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNEHYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKNDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVTAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(9995..10696)
                     /locus_tag="ACL3G6_000423"
     CDS             complement(9995..10696)
                     /locus_tag="ACL3G6_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M57 family metalloprotease"
                     /protein_id="HGR0545008.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWPQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETNE"
     gene            complement(10775..12007)
                     /gene="murN"
                     /locus_tag="ACL3G6_000424"
     CDS             complement(10775..12007)
                     /gene="murN"
                     /locus_tag="ACL3G6_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HGR0545009.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQNKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(12012..13232)
                     /gene="murM"
                     /locus_tag="ACL3G6_000425"
     CDS             complement(12012..13232)
                     /gene="murM"
                     /locus_tag="ACL3G6_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HGR0545010.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(13344..14123)
                     /locus_tag="ACL3G6_000426"
     CDS             complement(13344..14123)
                     /locus_tag="ACL3G6_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR0545011.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(14192..15853)
                     /locus_tag="ACL3G6_000427"
     CDS             complement(14192..15853)
                     /locus_tag="ACL3G6_000427"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGR0545012.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(16028..18250)
                     /gene="recJ"
                     /locus_tag="ACL3G6_000428"
     CDS             complement(16028..18250)
                     /gene="recJ"
                     /locus_tag="ACL3G6_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HGR0545013.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            18527..19285
                     /locus_tag="ACL3G6_000429"
     CDS             18527..19285
                     /locus_tag="ACL3G6_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0545014.1"
                     /translation="MVLVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAKKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDRMNMIIVTHEMGFAREVADRIIFMSDGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            19325..20089
                     /locus_tag="ACL3G6_000430"
     CDS             19325..20089
                     /locus_tag="ACL3G6_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGR0545015.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            20102..20779
                     /locus_tag="ACL3G6_000431"
     CDS             20102..20779
                     /locus_tag="ACL3G6_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0545016.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGATLLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            20789..21448
                     /locus_tag="ACL3G6_000432"
     CDS             20789..21448
                     /locus_tag="ACL3G6_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0545017.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLCILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            21706..22896
                     /locus_tag="ACL3G6_000433"
     CDS             21706..22896
                     /locus_tag="ACL3G6_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HGR0545018.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHSLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVSSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(23217..24098)
                     /locus_tag="ACL3G6_000434"
     CDS             complement(23217..24098)
                     /locus_tag="ACL3G6_000434"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HGR0545019.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(24237..25565)
                     /gene="vncS"
                     /locus_tag="ACL3G6_000435"
     CDS             complement(24237..25565)
                     /gene="vncS"
                     /locus_tag="ACL3G6_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HGR0545020.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(25562..26218)
                     /gene="vncR"
                     /locus_tag="ACL3G6_000436"
     CDS             complement(25562..26218)
                     /gene="vncR"
                     /locus_tag="ACL3G6_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HGR0545021.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(26267..26350)
                     /gene="pep27"
                     /locus_tag="ACL3G6_000437"
     CDS             complement(26267..26350)
                     /gene="pep27"
                     /locus_tag="ACL3G6_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HGR0545022.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(26530..27909)
                     /gene="vex3"
                     /locus_tag="ACL3G6_000438"
     CDS             complement(26530..27909)
                     /gene="vex3"
                     /locus_tag="ACL3G6_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HGR0545023.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(27961..28608)
                     /gene="vex2"
                     /locus_tag="ACL3G6_000439"
     CDS             complement(27961..28608)
                     /gene="vex2"
                     /locus_tag="ACL3G6_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HGR0545024.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(28621..29898)
                     /locus_tag="ACL3G6_000440"
     CDS             complement(28621..29898)
                     /locus_tag="ACL3G6_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0545025.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(30255..30425)
                     /locus_tag="ACL3G6_000441"
                     /pseudo
     CDS             complement(30255..30425)
                     /locus_tag="ACL3G6_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron maturase-specific
                     domain-containing protein"
     gene            complement(30711..31166)
                     /locus_tag="ACL3G6_000442"
     CDS             complement(30711..31166)
                     /locus_tag="ACL3G6_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545026.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKMPLLKN"
     gene            complement(31303..32187)
                     /locus_tag="ACL3G6_000443"
     CDS             complement(31303..32187)
                     /locus_tag="ACL3G6_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0545027.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(32191..32577)
                     /locus_tag="ACL3G6_000444"
     CDS             complement(32191..32577)
                     /locus_tag="ACL3G6_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HGR0545028.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(32570..33913)
                     /gene="cysS"
                     /locus_tag="ACL3G6_000445"
     CDS             complement(32570..33913)
                     /gene="cysS"
                     /locus_tag="ACL3G6_000445"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HGR0545029.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(34000..34884)
                     /locus_tag="ACL3G6_000446"
     CDS             complement(34000..34884)
                     /locus_tag="ACL3G6_000446"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0545030.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(34896..35513)
                     /gene="cysE"
                     /locus_tag="ACL3G6_000447"
     CDS             complement(34896..35513)
                     /gene="cysE"
                     /locus_tag="ACL3G6_000447"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HGR0545031.1"
                     /translation="MGWWHETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(35529..37742)
                     /gene="pnp"
                     /locus_tag="ACL3G6_000448"
     CDS             complement(35529..37742)
                     /gene="pnp"
                     /locus_tag="ACL3G6_000448"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HGR0545032.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMTGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            complement(38427..39293)
                     /gene="metF"
                     /locus_tag="ACL3G6_000449"
     CDS             complement(38427..39293)
                     /gene="metF"
                     /locus_tag="ACL3G6_000449"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HGR0545033.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(39357..41606)
                     /gene="metE"
                     /locus_tag="ACL3G6_000450"
     CDS             complement(39357..41606)
                     /gene="metE"
                     /locus_tag="ACL3G6_000450"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HGR0545034.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVVAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNSITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(41867..42133)
                     /locus_tag="ACL3G6_000451"
     CDS             complement(41867..42133)
                     /locus_tag="ACL3G6_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0545035.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            complement(42259..42674)
                     /locus_tag="ACL3G6_000452"
                     /pseudo
     CDS             complement(42259..42674)
                     /locus_tag="ACL3G6_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            42830..43831
                     /locus_tag="ACL3G6_000453"
     CDS             42830..43831
                     /locus_tag="ACL3G6_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGR0545036.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            complement(43899..46301)
                     /gene="pheT"
                     /locus_tag="ACL3G6_000454"
     CDS             complement(43899..46301)
                     /gene="pheT"
                     /locus_tag="ACL3G6_000454"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HGR0545037.1"
                     /translation="MLISYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEERQIVCGAPNVRAGIKVMVALPGARIADNYK
                     IKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDDE
                     IIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDKA
                     PYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDNF
                     EGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKSS
                     RVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGAT
                     VRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFTV
                     RVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAEG
                     AGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNVA
                     RKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYAK
                     GILEALFTRLGLQVTYTATSEIASLHPGRTAVISFGDQVLGFLGQVHPVTAKAYDIPE
                     TYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVKR
                     LTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNAE
                     VR"
     gene            complement(46378..46887)
                     /locus_tag="ACL3G6_000455"
     CDS             complement(46378..46887)
                     /locus_tag="ACL3G6_000455"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0545038.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(46887..47933)
                     /gene="pheS"
                     /locus_tag="ACL3G6_000456"
     CDS             complement(46887..47933)
                     /gene="pheS"
                     /locus_tag="ACL3G6_000456"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HGR0545039.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
BASE COUNT        13673 a        10992 c         9108 g        14464 t
ORIGIN      
        1 tctcatccgg ttttgcttgg cgggtttctg cggtcatttt ttcaaaaggg acccaccaga
       61 ctggcccaca gtccttgaga ccgtggccat tcatatcacc tcttcgtcta gggaaaaggt
      121 gccagtggag atgggcatcg ccatttccta gaagttcaat attcattttc tcagcagtaa
      181 agcccttggc aactgcctct tggactaaac tcatttcttc tagaaaatgg agtcttgtgt
      241 ccttttctaa aatggtgcaa ttccgtgaca tgttccttgg ctagaaagag actatagctt
      301 gcaaaatact gatggtctcc aatcacaaga tagcctgttc ccaactcttt gacaaagtag
      361 ggattttctc ccttcttgat gagctcaatt ctctggcaaa taaggcacat atcaatctac
      421 taaattgctt ctaagatagg catcgaccat tcgttctgtt gcgaccaccg agtcaatatg
      481 agtgcgctca taagaatgac tagactcgat acccgcacca agaagggcat gcttgacctc
      541 tgcccctgca gacatagccg ctgaagcatc cgaaccataa aatggataga tgtccagctt
      601 aaaaggaata tcttgctctt tagccaaggc aaccaagtgt tgacggaagt catagtgata
      661 aggacctgaa gcatccttga cacagataga tactgtgtac tcatctgtct gctggtcatc
      721 tcccattgcc cccatatcga cagctagata ttccaccact tgagttggaa tattggaatt
      781 agcaccgtgg cccacctctt cgaaaactga aaaagcaaaa tgagttgtta ctggcaattc
      841 aattccctct tccttataaa cacgaagaag attgagcaaa attgctgcgc tgaccttgtc
      901 atccaagtgg cgagacttga taaaaccagt ctctgtcaca acagttcgcg gatcgaaact
      961 aataaagtct ccaacctcaa tacccaaggc gcgcgtttct ttttcattgg ttacttttgc
     1021 gtccaaacgc acttccatat tgtcctgcgt acgttctgca gttcctgcat ccttgtagac
     1081 atgacaagaa gtctggtgga tgaggatggt cccagatacc gtttgacctg tgctagccac
     1141 atgaacggta cagttttctc cttcaatcat gttccaagga aaaccaccaa tacgatccaa
     1201 tttgagacgg ccatctggtt tgactgcacg aacaatagca cccagcgtat ccacatgggc
     1261 tgtcacatag cgttgttgtt catcattttg acctttaatg gtcacattga caccaccctt
     1321 agctgtacga acaggctggt aaccaagttt ctctaaagta tggactagat agtctgagat
     1381 ctcacgagta aagcccgttg gagatgcaat agcggttagt tctttgatat agtttatagt
     1441 ctgattcatt tcttcacctc tttcgctacc tattataaca catttatcat cggataaaaa
     1501 aagaaaatca ctcctgtaga cttggctaca aaagtgattt aagtgattat tccatttcaa
     1561 aaacatcgct ttcttgcttg tttggtagaa ccaatgagag caagattcca acaatggctg
     1621 gcaccaacca tgggagagat gccttggcaa aaggaagaac gctaacaaga tttgcaagaa
     1681 actcaacctt aaacgagctt cctagtacgc ttgcaatggc aataactgta accacagcaa
     1741 ttgtcaactg catacctggt tttgaaaggg caacaaattt gttgacaatg acaatcataa
     1801 cgatagcaat cgtgattggg tacaagataa ccagtactgg aattgagtac ttgataatcg
     1861 catcaagacc caaattggca atagcaaatc caatcaaggt aaaggctgtc gcataaacct
     1921 tgtagctgat ttgtgggaag cgctcattaa agaactcagc tgttgacaca atcaaaccaa
     1981 cagtcgttgt gaagcaggtt acggtaacca tagctgcaag gaagagttga gctgttgagc
     2041 caaagatttc ttgagtggct tgtgacaaga tgtaaacacc tggtgttcca cccttcatcg
     2101 cttcagctgg tactgggaaa tgatttccaa gaaaacctaa accgatgtaa agagcgctga
     2161 aggcaagggc aacaacgata ccaacaaccc aaatagttga aatgtattct ttcttacttg
     2221 aaaatccaag ttgtttcaag gtttgaactg cgattacgct aaaggccact gaggcaaggg
     2281 cgtccaaggt attataacct tctaggaaac ctgtaccaaa ggcagaagct tgataagcag
     2341 ctgaagcagc ttgaggactt gttccaccat atttgatagc tcccagaacg accaagataa
     2401 caatcaaaat tgcaaagact ggcgttaaaa tacgtccaat gcggtctaag atttttgatg
     2461 gattaagcga aatcaaatag gctaccgcaa aatacagaac cgtaaataca atcaagccaa
     2521 gtcctttatt tgcatccgac aaaagggggc taatccctac ttcgtaagct gttgtagcag
     2581 tacgtggggt agcaaagaat ggaccgattg acaagtaaag aactgagagg taaagagtcg
     2641 caaaccaagg cgctatcttc gttgaaatct cgtagatata tcctttagga tttagcgttc
     2701 caataataag ggtcaagacg gcgataccaa cgcctgaaaa gacaaaacct gcgatggcag
     2761 gaagaaaatg ttctccagat agagcaccta gagaaggcgg aaaaatcaag ttccccgcac
     2821 caaaaaatat tccaaacagg agcaaacctg ttagggtacc ttttttagcc ataaaaatct
     2881 ccttcatatt tataaaatac tgacctagta taccacgatt aggagtctga aaaaagcatc
     2941 acgaggcaaa tattaaatgt tttcaatttt cttaaaaata agaattatct aaaaacaaaa
     3001 ctctcctacc cagtccacac caagtaggag aaatgcaaaa ttttaaagtt cttcaaaggc
     3061 taacatgcca ccctggacat tgataacatt ataaccttgt tctaacagga attggcaagc
     3121 acgcgccgat ctcattccag atttgcaaat aatataatgc aagcgatctt tgtccaatta
     3181 atcataacta tcagccaatt gactaagcgg taggttgtgg gtaccttcta aatgaagagc
     3241 tgcaagctca tccacttctc tcacatccac tagagaaagc tggtcgtttt ggtaaagctg
     3301 ataaaatgcg tcaaaggcta tttctttcat tctttttctt ctaatactct tcgaaaatct
     3361 cttcaaacca cgtcagcgtc gccttaccgt gcgtatgtta ccgacttcgt cagttttatc
     3421 tgcaacttca aagctgtact ttgagcagcc tacgactagc ttcctagttt gctctttgat
     3481 tttcattgac tataaaatgg ttttaattct ttttttcaaa tctggcacta cttctgcctc
     3541 aaaccaagga tttttggaca tccagatttg atttcgtggt gatgggtgaa ctagcggaaa
     3601 ataggctggc agatagtctt tatagtgttt caccctctcc gttaccttcc cactgatttt
     3661 ctcctgtaaa tagtaggctt gggcatattg cccaatcaag agggttaact gaatatcagg
     3721 caattcctgt aagagctgcg gatgccattt ttctgcaaaa tctgtacgag gcggaagatc
     3781 acccgacttg ccatgtcctg gaaagtagaa atccataggc aaaacagcaa aataacctga
     3841 attgtaaaag gtatcttcat ccacacctag ccagtcccgc aagcggtcac cacttttatc
     3901 tttccagtaa aggcctgctt cttgagtttt aagtcccgga gcctgaccga tgatattgat
     3961 gcgagcagtt tttggcgcta caaagagagg ctcaatgcca cgctctgtat agctggcatt
     4021 ctgcgaatcc gccatgatag cctgtttgat tctttcgatt tgagacatct actttccctc
     4081 caaaaagaag tccaagcata agatctcaga cttctatcgt tttatttgat caattcgtaa
     4141 atagcttcgg cataaattgc tgctgctcgg aagagatcgt ccaaggcaat aaattcattg
     4201 gcttggtgca tagtatcaat tgagtctggg aacatagcac cataggcaac tccgcgctct
     4261 aacaagcgac caaaggttcc accaccgatg acttgttcat gaccttgtag gcctgtttgt
     4321 ttttcataga cattcaacaa ggtttgcaca agtggatctt ccattggcac atagtgaggg
     4381 gtatgaccat gttctgatag actgacagaa gcaactggca agttttctag gattgacttg
     4441 atttgttctg gacttgttcc ttttggatag cggatgttga gggcaatggt attatcagca
     4501 catgtttcat cgaagcggaa gacgcctgca ttcatagaaa gggcacccat cttttcatcc
     4561 acatgagcaa tcttgagact ttcaccctca tggtcgttca agagaatttt accagtgatg
     4621 tcaaggtatt ctttggctgg accagcaaag tcaaactggc taaggaagag ggctaggtaa
     4681 gtcgcaccat tgacacctga agcaggcata gcaccgtggg ctgatttacc aatgatcgtc
     4741 accttgtatt tgccagcttc ttcttggagt tctcctctaa gtttgtgttc tgcaacaaag
     4801 gcatctagtt tagcttgcaa gtcagccaaa tcacctgaaa cgactgctgt tgctgattct
     4861 ggtaccatat tttcacgtaa accacctgta aagctgtgaa gacgggcagc acctgtattt
     4921 tctcctgcaa agtggaggta ttccgtgata tttccttttt caccattgat gatagggaat
     4981 tcagcgtctg gagagaaacc gaaatctggt ttggcaagtc ctacgtgctc aaagtagtag
     5041 tccatatctg cccagcctga ttcttcgtct gttccaacga tgaagcgaac tttcttagaa
     5101 gttggaagac ccaattcttt gatgattttc aaaccatagt aacaagctgt tgtaggaccc
     5161 ttatcgtccg aagccccgcg cgcataaagg cgaccatctt tgatagttgg tgtgtaagga
     5221 tctgtatccc aaccgctacc agctggaacc acgtccatat gggcaaagat tccgagaact
     5281 tcttctccat caccaaactc aaaatgtcct gcatagttat caacattttt agttggataa
     5341 ccatcacggt ctgcgatttc aaggaatttt tccaaggctt ttactggacc aggtccaaat
     5401 ggatgttggg catcagcctt gctatcatca cgttctgagt tgatttccaa aaggctaaac
     5461 aagtcagcca agaggtcttc tttgcgtttt tctacttctg ctgtaaaatc aattgctatc
     5521 attttttctt cttcctatct tttttcgatg atttcatcta ctggcaagcg gtagcttggt
     5581 tccaatttgt cgtctgtgta acccactgtg atcaagagtt ctgggcggaa acggtcttcg
     5641 atttccaaaa cttcattaac ttttgatttg tcaaaaccaa ggataatatt ggaaccaatt
     5701 ccttggtctg taagagcgag aaccaagttc atagcaacca aacctgcatt gagtgctagg
     5761 tagtcgctga cttgttgttc attgtagcgt gcaaattcag ctggcaaatt tttcatgaag
     5821 tattgaagtt gttcttctga gaaattgtta gcaccaccaa ctcgggcaat cttacgagcg
     5881 cgtttggcaa ggtctgtatc tgtaaatagg gcaatggtta caggtgctga tgatacctgt
     5941 tcaaaattgg aaccataagc taactttgcc agttcagcat ttttctcaca taccaccaca
     6001 aatttccaag gctggctgtt gtgggcgctt ggcgccaagg ttgcaatttc gatagccgta
     6061 cgcacatctt ttggatcaac aggcttatca gtgaaatgct tggtcgcatg acgtttttta
     6121 tttaattcaa gaaatttcat aatcgatttc cttttctaat tctactgctt ccattctacc
     6181 ataatttgaa agagcttgca gggatttttc atgattaagt ttttctatca cagacataaa
     6241 agatatatat tggtttatca ggaaagtttc tgataaacta gcaagtactt tacatttgaa
     6301 tggagacagt atgaaaaaat ttagcctatt actagctatc ctaccatttt tggttgcctg
     6361 tgggaatcaa gctacaccca aagagtccag ctctcaaaag acaatcgtcc ttgctacagc
     6421 tggcgatgtg ccaccatttg actacgaaga caagggcaat ctgacaggct tcgatatcga
     6481 agtcctaaaa gcagtggatg aaaaactcag cgattacgag attcaattcc aaagaactgc
     6541 ttgggagagc atcttcccag gacttgattc tggtcactat caagcagcag ctaataattt
     6601 gagttacaca aaagagcgcg ctgaaaaata cctctactcg cttccaattt ccaacaatcc
     6661 cctcgtcctt gtcagcaaca agaaaaatcc tttgacttat cttgaccaga tcgctggtaa
     6721 aacaacacaa gaggataccg gaacttctaa cgctcaattc atcaataact ggaatcagaa
     6781 acacactgat aatcccgcta caattgattt ttctggtgag gatattggta aacgaatcct
     6841 agaccttgct aacggagagt ttgatttcct agtttttgac aaggtatccg ttcaaaagat
     6901 tatcaaggac cgtggtttag acctctcagt cgttgattta ccttctacag atagccccag
     6961 caactatatc gttttctcaa gtgaccaaaa agagtttaaa gagaaatttg ataaagcgct
     7021 caaagaactc tatcaagacg gaacccttga aaaactcagc aatacctatc taggtggttc
     7081 ttacctccca gatcaatctc agttacaata acactcttcg aaaatctctt caaaccacgt
     7141 cagctttatc tgcaacctca aagctgtgct ttgagcaacc tacggctagc ttcctagttt
     7201 gctctttgat tttcattgag tataagatat ataaaagcga ttggactacc aatcgttttt
     7261 agtttgcatt ggttatttta ggaaactctt acaaaaaatc aaaaaaattc ttcacatcct
     7321 ctacatacct atgcttttct attaagcttg ctaatagttt cagattgtgc ctctgatagt
     7381 tatcttcacg acgtagttct tcatacattt cgataaaggg aagccccttg gatttggcca
     7441 attctaactc agcctcgtaa tcataagcaa ctttacgaaa ttggatattg agtaattccc
     7501 catcttcaac ctctatcacg gcatactggg cacggtgatt ttttaacgcc tcccaattaa
     7561 aatagggcat gccaatcgac cctggattga tgatttgttg ccctttactg ccgtagcgaa
     7621 gcaactgctt gtgaacatga ccataaactg ccacgtccgt ttccgcatct agcagttggt
     7681 caaatttctc tgtatcattc tcaactagca agtcaccacc atagtttttg tcaggtaaat
     7741 tatgagagat agaaaagcgc aatccgtcaa tttctttctt ttccagcaaa ggcaagcttc
     7801 gtagccagac aatcgttgca ggatccattc gctccatcaa aaactgggtc atgcgcattg
     7861 actggatttc tttcggatat tccaaaccat attcgccatc caagacctca aggacacgat
     7921 catcccaatt gcctcgaaca cttgctgtga taggaaggtc ctttagcagg gcgactaagt
     7981 catttgcgcc tggaccagga agaaaaatat ctccctgaag ccaatattca ctggcccctt
     8041 gatttttagc atctgcaatc actgcttcta gcgccgtcgc attgccatga acatctgata
     8101 aaattgcgat tttatggttc attgtggttt ccttccgttt ggtaatctac tctttcttct
     8161 gctacttgag gcaaggcttc tccctgcggg ttcaactttc tttgcacagc ctctgcaacg
     8221 actctaggta ccccaacttc gacaatctca tccacactgg cttccttgat tttggtcaaa
     8281 gacttgaaat gcttcataag attctgcttg cgtttaggtc ccagaccgtc aatcccatcc
     8341 aattgagatg agaaagaatt tttggagcgc agttggcggt ggaaagtgat agcaaagcgg
     8401 tgcacctcat cttggatgcg ttggaggagg aaaaattcct gagaattgcg agacaagtcc
     8461 accacctcaa gcggatctcc aaagagcaat tcatgggttt ggtgcttatc attcttttgc
     8521 agcccagcaa ttggaatatc caagcccagt tcctcttgga tgacttgctt agcaatattg
     8581 acttgacctt gccccccatc aatcacaatc aaatctggag gagtcaaagc ctcacgctgt
     8641 actcgaccat agcgtctgcg aatgacttct ctcatactag catagtcgtc cggcccaaca
     8701 acggttttta tcttgtactt acggtaatct tttttacttg gcctgccgtt aacaaagacc
     8761 accatggctg aaacaggact ggtccccatg atgttggagt tatcgaagga ctcgatgcga
     8821 actggagtcg gaatttggag caaacgtcct agattttcaa tagctccttg ggtcttttcg
     8881 actgattttt ctagcagatt gaacttctgc tctagactaa cacgagcatt ttttatggct
     8941 agattgacca gctgtttttt ctctccacgt tggggtttga gaatcttggt atccaccaaa
     9001 gccttgacag cttcttcgtc aatatcctgc ggaatcagta cctcattggg aactaggtga
     9061 gatttttctt gatagaattg tcccacatag gtcaagaaat cctcatctgg atcattgaag
     9121 taggggaaga gattgacatc gcgctcgatg agcttgccct gacgaacaaa gaaaacctgc
     9181 acacacatcc agcccttatc cacatagtag ccaaagacat cgcgattttg gagatcctta
     9241 gccatgaccc gttgcttggt tcgaagtgtt ccaatggcct gaatcaggtc acggtattcc
     9301 gctgcccgtt caaactccat actttgtgct gttactgcca ttttactctt gagatcatcg
     9361 atgattttgt catcctgacc tttcagaaaa tcagacacct cctgggccat ggacttgaaa
     9421 taggcctcgt cattcttaca gatggtgtgg gccatacatt ggccgatatg gtagtaaaaa
     9481 cagaccttag agggcgggtt ggtacatttt cgaaaaggga aaatcctatc tagaagtcgc
     9541 ttgatttcat tggctgcccc cacatctgga taagggccaa aataaagacc accgtccttt
     9601 ttgacctgac gagtaatgat aagccgtgga tagtgctcat tggtgatttt gataaaagga
     9661 taagacttgt catccttgag catgatattg tacttgggct tattttcctt gatcaggttg
     9721 atttccagca gaagcgcctc aatattagac tccgtaacaa taaattcaaa atccacaatt
     9781 tcagacacca aggcctctgt tttggtatca tgacttccac ggaaataaga cctcacgcga
     9841 ttacgcagat ttttagcctt tcctacatag ataatggtgc cgtttttatc cttgtaaatg
     9901 tagcaaccag ggctggtcgg caagagctct agttttggtt taatcaagtt gttcatagtt
     9961 ccattatagc aaaaaagtag ggaaagatag taccctactc attagtctca tatatttttc
    10021 ggaggtttgc aacatcctct tcctggatac cataaaagga acctgctggt tgcatgacag
    10081 acttctcatc tgtatggtcc aagccaatcg catgacctaa ctcatgttct gccgtatgga
    10141 caaggcgttc ataggaatag ccatagtatg gattggacaa ataataatga ttcaaccgca
    10201 ccgttacgga caagaattgc cctgttaaga gattagtttg actttccgcc tctcctgcca
    10261 caggagtgcc tccgtcgttc atctccgtag ccgtaatatc cgccttacta gactcagtca
    10321 cgagttcaaa gttaaaagca ccagtttgat tccagttctg gattgcttct aaataagcct
    10381 cttgaaagcg tgaatccatc tgcggatcca ggtaaatacg agcagaggcc tgtggccacc
    10441 ttccttcaga atgctggtga ctatctgtct ggcttaactt aggcagttgc cctgttttct
    10501 cccattggtc aatactttgt tgaccaattt ttactgaccg ttctgcttgc tttagcgctc
    10561 cttgaaaatc cccgttcaga taccagagaa gtccgaaagc aagcacacat aagagcacaa
    10621 ctatccaaac cagacgccaa aacaaacgcc acacaaaaga aaagaaagcc cctatcaaac
    10681 gaaaaagcca gcgcatgtct ctccaccttt ctagcaaata aaaattattt tactaaaaga
    10741 agctaaaaga aatctaaata ctgacttttt catcttaacg tcctactatt tttttgagta
    10801 actggatagc tttgtatttt aaaggagatg gatggtaacg gaaagtacct gctttgcgta
    10861 caatatagcc attaaaattc tgtttaaaac gcaaaacacc atcacttcca tcaaaaatcc
    10921 cttgaatgcc taggaagttg tatttaggta ttccacgttt tatgctttcc aacataacat
    10981 atttttgaag cagtgcaggg gcatagaact tattaaactc agtgtaggaa ccactaaaga
    11041 gataagtcgt ttcctgaggc atataaacaa ataaactccc agctaaaaca atatcttctt
    11101 ctccatattt ttcaatcaag tctcgcgctt ctgcttttcg aacttcaaac gtttcaaatt
    11161 gactagaata ttctctcagt tgattttgtt ttttctcaga atgaggattt ttactcaaat
    11221 caagtcgcaa cttgtccaag ttttcttcta gtttattttg ttcaccttgc aatttgctca
    11281 tatagtccga aaaatttaag cttgctatga gaaactccgc ttgttctcca aaagtatcat
    11341 aaaaatgctc ataatattct aaacttttat cactatattc tctacgttca gaggtttctt
    11401 ttgttatatt cttaaaaatc gatagttctt cacgttttaa ctttttcaat cgaatgccaa
    11461 aggtttcagc ctttttcacc aagggtttac cctttttgct aaaactttta agcaaactct
    11521 tttcagttaa ttcagttaaa tctttatagt ataaccaatc tggttctcca cctgggtaac
    11581 ctgttgttaa gccatcaaat tgataaccta aatcagtcaa accttgaata atactttttt
    11641 tctcagcatc tattggatta ccttggctat caaaagtttg ataagtttca taaggtttta
    11701 caagcaactc taatacacca ttttgcttgg catattcttt taactctgca taaaaaactg
    11761 gaagagcatc ttgttgggta taaatcggcc ccgaattgag ttccatatgc agaccaccca
    11821 gcatgggcaa gctataaacc agagctgcaa cttgaatttc tccttcttgt ttcaaagcaa
    11881 gataaacaat tcgagcccct cttttttcta gcaaatcccc catctggaca gattgcataa
    11941 aggaacgaga agaaacctga tcagaataag tctgaaactc ttctttcgtg agtgttgtta
    12001 gtgccatata cttactttct atgttttttt cttaatgttt tacggaaatc aagagcaagt
    12061 cttaacagag gatagagagg atgagtgggc attgtaaatt cacccaagta ttcttcaatc
    12121 gttggattaa atttttcctt aaaatgataa agtccaccat tgagagagtt ttcaacacca
    12181 cctaaatttt gccagaccat acctcgctca aaggcatagc gagccgtttc ataccatgtt
    12241 aaaattggtg cattgtaacg tttaaaatca tcatccatac cagcatatat attgacagag
    12301 gtagtaccaa attccaaact caaagtagcc gctaaaggaa ctctcgcttg acctacatct
    12361 atatattcct gcaagaaggt caattcctct aacaaacgtt ctttttcctt cttctgcgct
    12421 tctacttttg aagttcgagt cgactcagta aaggtctctt ccaaggctct atttttcgct
    12481 aactgttctt ctaattcttg cgaacgttta gaaacatcca aggtggccaa ggtgatatag
    12541 gccttgtcct taaaattatc taacaatttt ttataatagg cttcattcct caaatgaatc
    12601 tcttttcgct tctcagtttt tttcatcaac tccgaaaatg aatctaatag ttccagtcca
    12661 ccatattgaa tctcaagccc tttgtttcgt gctgttcgaa tagcctgttt tgttgacttg
    12721 gaaagtttat cttcttcaaa attttccttg tatattttcg cctgaatacg aggttgaatg
    12781 gtgtctccca tttcctccgt ttttcctgac caccttactc ccatttgttg caaactatca
    12841 ataatagcca gattttcagg aaattctgtc ttttcctgat tgattaaact ttgagatagg
    12901 caaatacttg ggtcaaaagt cacaaaaacc gctctcttac tgcgagcata ggacttaata
    12961 gactgaatgg caaaattcaa gagttcttta tccccataat ccaatatagg tcctcttggg
    13021 atgtaaaaca ttttatagcc tagcggaaga gttctaatca aaatactagc tgtcgccagt
    13081 aatttttctt ccctgtaaac accaaacttc tcatgttgcc aattagactt aacttcctcc
    13141 caagcactac tttgtaatac attggctaat tcatgttctt tgacaaactg atcatattct
    13201 aatgtgggaa tgccaatttg ataacggtac atttcctact ctctttcctc cagtatttta
    13261 ttactattct actactttcg tttgaaaagt ctagtgaaaa catattttat tttagttcta
    13321 ctccccctat gctgaagttc aaactaagtc agtctctctt ctaatttgaa atcaattggt
    13381 agggttgtta aaaaaacttc caattgtttt tcccagtagt accactcgtg agttccagca
    13441 ctatggctat aggtcacatc aaaacctagt tttttgagat ttttcactgc gagattattg
    13501 gcttcgtaca agaaatcctg ttcgccacac cacgcccaaa gtttggtctt tttatccgat
    13561 tttttagcca gactttcaag agaataggga ctagttgtcc agtctctaat ctctccaaaa
    13621 acacctctcc agtaggctgg acttcccaga ttttgacttt caggagaaaa gttttgaaag
    13681 ctgagggcac ctgaaaaact agctgcatga gaaaaacgat ttgtcgtaag agccagtttg
    13741 aagcagccgt agcctcccat agaaagacca gcgataaagg tcttttcacg cttgctagtc
    13801 atattaggga agaagcgttt cagaacctgc ggcaattcct ctgctagagc cgtgtagtag
    13861 tcaaaaccat actgggtatc ggtgtaccaa ccattgctgg tattgggcat aacaacgatg
    13921 agattagttc ctcgaagcaa gcgttctaca ttggtccgct taagccaact attatgattt
    13981 ccagacatcc cgtgcaaaag gtacaagacg ggaatatctt cacactctgg ttcttccact
    14041 cgattggcat cagggtagag gacattcacc ccccactcca tatccaatac ttgtgagtaa
    14101 tactcgattt tcattactgc catgattttc tccttctatt tttctataag aaaaagccga
    14161 aactcgactt tctctctgtt tatttcaacg attattttgc ttccatgact actggtaaaa
    14221 tagctggacg acgcttggtt tggtcaaaga gatacttggt caaattatct cgaaccttcc
    14281 ctttaagatc tgcccagtca aagtcatctc cttgaagata atcttctacc gtttggttaa
    14341 tcaattctga actttcacgg agaatatcgc gactcttctt gagataaaca aatccacgcg
    14401 tgtgaacacg agccctagcc acaattttct tctcacgacg gttgactgta atagccacga
    14461 tgaaaattcc atcctctgac aagaccttac ggtcacgaag aacaacattt ccaacatcac
    14521 caatggcatt cccatcaatc aagatatctc ctgctgaaac cgatccagct ggaacaaagt
    14581 ctccattctc gtaagccatg gtcgtcccct ttttaggaat gaaaatgcgt tctggcaaca
    14641 tcccaactgc catggcagcc ttagcgtgag catccaactc acgatactcc ccttggacag
    14701 ggaagaggta cttaggttgc aaaagattga tcatcagctg caaatcacgc acatttccgt
    14761 gccctgatac atgtaaactt tgggtaatca atttgacaac cccacctgcc tgataaatca
    14821 tattttccac acgcgcaaca aaggcttctt tagcaataga cggagccgta gcaatataga
    14881 ccaggtcccc atccttgatt tctacataac gatggcgacc aatcgacatc ttacgaagtc
    14941 cattgatagg ttcacccata cgacctgtct caagaataat caactcatgg tcttcaaagc
    15001 gagacatatc tttaggctta atcaagagaa tttcgttggc taaagacaac ttcttaagac
    15061 gaatcgctgt gcggacgata ttttcaatat caaatcctgt caagacgata cgtcgacctg
    15121 ttttatccgc agcgtcaaaa atctgctgaa tacgagaaag attactggaa acagctgcaa
    15181 cgatgatacg accttcccag tcagcaatag tttgggtaat ttcatcccta acttcacttt
    15241 cactagccac ctgaatattg ctgtctgcat tggccgaatc actgaggaga gccaggacgc
    15301 cgtcacgacc aatctctgcc aaacgagcaa aatcagttgc ataagattca ctagccgttt
    15361 ggtcaaattt gaagtcacct gtataaacga tgcttccttc cgatgtcttc aagacaattc
    15421 ccagactctc tggaacggag taagtcgtag ggaagaagga aaccactgtc ccaccaaaat
    15481 caatctccgt attctcatca atgacatgga aatcattaaa tttcttaacg gcatcatttc
    15541 ctttgacaaa gagctttgcc aactcaatgg tcaactcaga cccaaataca ggaactttag
    15601 cctctgccaa gagataaggt agagcaccaa tggcatccgc atgcccgtgg gtcaagaaaa
    15661 ccccagcaat acggtcgcta ttttcaaaaa ggtaatccat gtttggaatc accacatcga
    15721 cccctaattg ttcattttca ggatatttta accctacatt caaaacaaaa atggactctc
    15781 caatttcagc aatgtacata ttttttccat tctcacgcac accaccaagt gttgttaaac
    15841 tgatattact catttttcct ccaaaatctt agtttatctt gattataggg caattctacc
    15901 ctcttattct aaaagttctg atactttcag ccgaatcttt tcctaccatt ataccatttt
    15961 tttgatgatt ttcaaaatga aggtctgttt tcaaaaaaga gttgatttcc caactctttc
    16021 ctaacttcta ctctttttcc atcaaaaaat cataaatttc ttgcaccgta cccagcgcca
    16081 tcatttcttg gtctttaacg gtttgtttga gattttggta aatttgactt tctcctatct
    16141 cccgctttgg cgcctcttta ttgactgtca tcacaccatc ttttatcgtc acaaagccta
    16201 gttcttcaaa tacttgaatc atcttgacca gcaagatttg ttgaatatta agatatgcag
    16261 ccaaatcttt cagcttgtag cgaatatcaa actctgggaa ctggtaaata gtcttgtaca
    16321 atttagcaaa ctgatctcta gtcccataac ctgtcagata ataggtcttg tcaatatcat
    16381 ttttgaaata gacagcagag aaatgctgtt cctgaaaaat ggtcttcagc tgagtaatat
    16441 cctctggaat gttttttacg acaacagctt cactagccgc aagatttggc agttctccag
    16501 gaaaatccaa gactggaaca ccttctggca agactgcatt ttttccacga atgttaaaaa
    16561 gttgaacacc ttccactcgc gcatccacca tcatcaactg gagggcagtt tggccattcc
    16621 attggttgac agacaattta accgctaact ctagattctt ggtttgagaa aactctgtcg
    16681 cccatctgcc ttgaccaaag gctaccactt caaaactcgc ctcacccttg gaaattttca
    16741 gctttagatg ggcattacct gcccccatag tacgagcact ttcgacctga aaattcttga
    16801 tataaaaaat aggtttctga ttatccattc caaaaggagc taaacgttca aaacttttga
    16861 ccgtttccaa gctaagtgcc tccaaatcca actcttcatc taggtttaac ttattcttgc
    16921 caccagcatc tgcacctttt tcacgaacat aatcttccaa aacctgagat aaatctgaga
    16981 gttgctcaac ttccagcgtc atacccgctg cacctgcatg acctccaaag gcgatgaaga
    17041 ggtctcgatg gggatccaga gcttcaaaaa tatcgaccgc ttccacacta cgagcactgc
    17101 ccttggcacg accgtcttct atattaagaa caatgactgt ctgtcccaat tcttccaata
    17161 aacgaccagc cacgattcct agaaccccag gattccagcc ttccttggcc aagacctgaa
    17221 ccttcttctc aggatccacc atggtcttgg cttcttcata gatagactga acgatttcct
    17281 tgcgctcttc gtttttctgg tgaatcataa gggcaatctc atgcgcttcc tcatcatcaa
    17341 atccagtcaa caaatcaatg gcaggattgg gatcatccaa gcgacccaag gcattcaaac
    17401 gaggagcaat ctggaaacca accgtttctt ctgttacttc gttggcagca atcccagcca
    17461 tgtccagcat ttcttgcaga ccaatgcgct gggtatgacc caacatttcc agaccatatt
    17521 gaactaagat acgattttca tccgtcagac tcaccatatc tgcaatagtt ccaatagcga
    17581 ccaaatcaag caattccact tgcacttctt ctaacagggc acaagccaac ttgaaagcaa
    17641 ctccacaacc agccaaatat ttaaaaggat aatccgcatc tggatgttca ggatggacaa
    17701 tagcataagc atctggcagg gtttcaggca tggaatgatg gtctgtcaca atgacatcta
    17761 ctcccataga ctgagccaat gcaatagcct catgaccagc aaccccattg tccaccgtca
    17821 caatcaagga aattccttct tgctcgataa agtatttata aacactagca ttagggccat
    17881 agccatcggt aaaacgattt ggcaggtaaa ctcggcactc agcaccaagt tgttccaaac
    17941 tttccttcac aatagaagcc gaagtcatgc catccgcatc atagtctcca taaacgagaa
    18001 tattttcccc ttcttcaata gcctgacgaa tccgctccac tgccttgtcc atatcatgga
    18061 gcagataagc atcatgtaag tcctccaagg aaggttctaa aaacttcttc agactttctt
    18121 ggtcctgaat ccctctctca aacaataacc gagccacctc aggacccagt ccagccttct
    18181 tggctatctt tgtaaaatcc gcatcttcta cctgcagggc aaactgccat tcataagtag
    18241 gtgttatcaa aaagacatcc actctttcta agaattctat tgcttcatta taacatgatt
    18301 tagacgtttt ctctatccag attgcttttt tataacattt tatagtatat tgaaactaga
    18361 atagtacacc tctacttcta aaatattgtt agaaatcgat ttgactgtcc cgatcgattt
    18421 ttcctgttct tatttcacta tagtgaattt tttcagatat gatttgacaa gaacattctt
    18481 ttattgcaga atcgtgttat aaaatctaac ataaaggagt tctctcatgg ttttagtaga
    18541 atttaaaaac gtcgaaaaat attacggaga ctaccacgca ctccgcaaca tcaatctccg
    18601 ttttgaaaaa ggacaagttg ttgtcctgct tggaccttct ggctctggga agtccactct
    18661 tatccgtacg atcaatggtt tagaggctgt tgacaaagga agtctcctag tcaatgggca
    18721 ccaagttgct ggtgccagcc agaaagattt ggtacctctt cgcaaggaag tcggcatggt
    18781 ttttcaacat tttaaccttt atccacacaa aacagtgtta gaaaacgtga cacttgcgcc
    18841 cattaaagtt ctaggaattg ataaaaaaga agctgaaaaa accgccaaaa aatatctgga
    18901 atttgtaaat atgtgggaca agaaagattc ctatcccgcc atgctatctg gtggacaaaa
    18961 acagcggatc gccatcgctc gtggtcttgc tatgcatccg gaactcctcc tctttgatga
    19021 accaacatct gctcttgatc ctgagactat cggagatgtt ctagcagtta tgcagaaact
    19081 ggcgcgtgat aggatgaaca tgatcatcgt tacccacgaa atgggctttg ctcgagaggt
    19141 tgcggaccgc attatcttta tgtccgacgg agaagtttta gtagatacga cagatgtcga
    19201 taactttttt gacaatccaa gcgaacctcg tgcccaacaa ttcctcagca aaattatcaa
    19261 ccacgaaagt gacaaagtca aataaggagg cgcctatgaa aaaaaattct ttttatcagc
    19321 attattgatt agccttttcg gccttgctgc tgccaaacca gtccaggctg atacaagtat
    19381 cgcagacatt caaaaaagag gcgaactggt tgtcggtgtc aaacaagacg ttcccaattt
    19441 tggttacaaa gatcccaaga ccggtactta ttctggtatc gaaaccgact tggccaagat
    19501 ggtagctgat gaactcaagg tcaagattcg ctatgtgccg gttacagcac aaacccgcgg
    19561 cccccttcta gacaatgaac aggtcgatat ggatatcgcg acctttacca tcacggacga
    19621 acgcaaaaaa ctctacaact ttaccagtcc ctactacaca gacgcttctg gatttttggt
    19681 caataaatct gccaaaatca aaaagattga ggacctaaac ggcaaaacca tcggagtcgc
    19741 ccaaggttct atcacccaac gcctaattac tgaactgggt aaaaagaaag gtctgaagtt
    19801 taaattcgtc gaacttggtt cctacccaga attgattact tccctgcacg ctcatcgtat
    19861 cgatgccttt tccgttgacc gctctattct atctggctac actaataaac ggacagcact
    19921 actagatgat agtttcaagc catctgacta cggtattgtt accaagaaat caaatacaga
    19981 gctcaacgac tatcttgata acttggttac taaatggagc aaggatggta gtttgcagaa
    20041 actttatgac cgttacaagc tcaaaccatc tagtcatacc gcagattaag gaggataccc
    20101 tatgacagat ttatcatctt ggacagccta ttttcaggat tttggacaat ttttcaatgg
    20161 tttcctcttt actcttgccc tagcgattgg atcctttatc ctcgccatgg tcttaggaat
    20221 cttctttggt gccatgtcaa ccagtaaacg tccaatttta cgcattttag ctcgcatctt
    20281 tgtggaattt taccaaaata ctcctctctt ggtgcagttt gttattgttt tttatggcct
    20341 acctcttatc agtgaccata tcatcatgat tccaatttat tggacagccg ttctctgcgt
    20401 gggactctat cacggcgctt atatcgctga ggttattcgt tcagggattc agtctattcc
    20461 tagtggtcag atggaggccg ccttgtcgca aggttttacc tatatcagtg ccatgcgctt
    20521 gattaccttg cctcagacct tccgcatcat tctccctcca ttgaccaacc aaattgttaa
    20581 cctcatcaag aacacctcta ctgtagctat catctctgga gtagacttga tgtttgtgac
    20641 taagtcttgg tcggctctca acggaaacta tatcccagcc tttttaggtg ctactcttct
    20701 ctactttgcc ctatgcttcc ctgttgccca gtttggtcgc aagatggagc aagccaacaa
    20761 aaaagcctat tcactttagg aggttactat ggaatctatt ttagaagttt taaccccaga
    20821 taacctagtc tttatcttta aaggatttgg cttgaccctc tatatttctc tgattgccat
    20881 catcctctct actatcatcg gtacggtgct agctgtcatg agaaatggca aaaatcctgt
    20941 cttgcgaatc atctccagca tttatatcga atttgtgcgc aacgttccca accttctctg
    21001 gatttttact atctttttgg tgttcaaaat gaaatccaca ccagcaggta ttacagcctt
    21061 tactctcttt acatcagcag ccttggctga gattattcga ggcggtctca atgccgtaga
    21121 caagggacaa tacgaagcag gaatgtcaca aggcttcacc tcagcccaaa tcctctacta
    21181 catcattctc ccacaagcca tccgcaaaat gctaccagcc atcatttctc agtttgttac
    21241 cgtgattaag gataccagcc tcctctactc tgttatcgcc ctacaagaac tctttggagc
    21301 cagccaaatt ctcatgggcc gttatttcga accagagcag gtcttcagtc tttgcatcct
    21361 gattgccctc atctacttca gctttaacct agcaatttct agcctgtctc atatgctagc
    21421 caaacgttgg caacaagctg cagaataata ctcttcgaaa atctcttcaa accacgttag
    21481 ctctatctgc aacctcaaaa cagtgttttg agcaacttgc ggctagcttc ctagtttgct
    21541 ctttgatttt cattgagtat aaacagccac tctccagttc aattggagag ttttttgatg
    21601 agagtagata tttatagacc tcaatttgac accatacatt ttctatgata aaatgtaaca
    21661 aatttattta caacaaatcg aaatctagat gaaatggaat tttctatgaa atcagtcaaa
    21721 ggactactct ttatcatagc tagttttatc ttgactcttt tgacttggat gaacacttct
    21781 ccccaattca tgattccagg actagcttta acaagcctat ctctgacttt tatcctagcc
    21841 actcgtctcc cactactaga aagctggttt cacagtttgg agaaggtcta caccgtccac
    21901 aaattcacag cctttctctc aatcatccta ctaatctttc ataactttag tatgggcggt
    21961 ttgtggggct ctcgcttagc tgctcaattt ggcaatcttg ccatctatat ctttgccagc
    22021 atcatccttg tcgcctattt aggcaaatac atccaatacg aagcttggcg atggattcac
    22081 cgcctggttt acctagccta tattttagga ctctttcaca tctacatgat aatgggcaat
    22141 cgtctcctta catttaatct tctaagtttt cttgttagta gctatgccct tttaggctta
    22201 ctagctggtt tttatatcat ttttctatat caaaagattt ccttccccta tctagggaaa
    22261 attacccatc tcaaacgctt aaatcacgat actagagaaa ttcaaatcca tcttagcaga
    22321 cctttcaact atcaatcagg acaatttgcc tttctaaaga ttttccaaga aggctttgaa
    22381 agtgctccgc atcccttttc tatctcagga ggtcatggtc aaactcttta ctttactgtt
    22441 aaaaattcag gcgaccatac caagaatatc tatgataatc ttcaagccgg cagcaaagta
    22501 accctagaca gagcttacgg acacatgatc atagaagaag gacgagaaaa tcaggtttgg
    22561 attgctggag gtattgggat cacccccttc atctcttaca tccgtgaaca tcctatttta
    22621 gataaacagg ttcacttcta ctatagcttc cgtggagatg aaaatgcagt ctacctagat
    22681 ttactccgta actatgctca gaaaaatcct aattttgaac tccatctaat cgacagtaca
    22741 aaagacggct atcttaattt tgaacaaaaa gaagtgcccg aacatgcaac cgtctatatg
    22801 tgtggtccta tttctatgat gaaggcactt gccaaacaga ttaagaaaca aaatccaaaa
    22861 acagagctta tttacgaagg attcaagttc aaataagtaa tcatactctc ctgggatttc
    22921 ccaggagagt tttttatagc caaatgaaat aagacaggaa cgatggaatt ttggcattca
    22981 aatcaattga taagaatgtt ttatagtgga gtgaaatagg atacgaacaa attgattagg
    23041 aaaatcaaat gaatttatag aaatctttta gcagttatgt tgtcctattc tagtttcaaa
    23101 acgctataga agcagcattg tgctagtcta gattcagttt actatactaa aacgagtagc
    23161 ttgaaatcaa aaaacccacc ctcacaggca ggttttatct gtattattca gctagattat
    23221 gctttacctt ctgaaccgaa tacgtcgata cgttcttcaa ccgatgcttg gatagctttt
    23281 acaccgtcag ccaagaattt acgtgggtcg aagagttttt tcttgtcgta ttctgcttcg
    23341 tttgcttcgt agtcacgagc aaatttacga gttgcgttag cgaatgcgat ttggcattct
    23401 gtgttaacgt taactttggc aacaccaagt ttgatagctg cttggatttg ctcatcagga
    23461 atacctgatc caccgtgcaa tacgattggg aatcctggaa gagcttctgt caatttttgc
    23521 aagtggtcaa ggtctagacc ttcccagttt actgggtaag ggccgtggat gttaccgata
    23581 ccagctgcca agaagtcgat accagtttca accattgctt tagcgtcttc gattggagcc
    23641 aattcacctt taccgatgat tccgtcttct tcaccaccga tagtaccaac ttcagcttct
    23701 actgagatac ctttagcgtg tgctttttca acaacttctt tagccaattt aaggttttct
    23761 tcaactggaa ggtgtgaacc gtcaaacatg attgaagtat aaccaacttc gatacactca
    23821 agtgcatctt cgtagtgacc gtggtcaagg tggatagcta ctggtacagt gatacccatt
    23881 gattcaacaa ggttagcgat caagttgcga gcaactttgt aaccacccat gtatttagca
    23941 gcacccattg aagtttggat caaaactgga gcttttttag cttctgctgc gcgcaagata
    24001 gcttgagtcc actcaaggtt gtttgtgtta aatccaccaa ctgcataacc gttgtcacgg
    24061 gctgcttgga caaatttttc tgctgaaacg attgccattt tatcaggcct cctgtatatt
    24121 tttatgggtc atcccattta cattgttcat tttatcactt tttgccaaaa aaatctagtt
    24181 tttcccgcag tttcgattga ttttcttcta actccatcta tgtaaaccct ttctccctag
    24241 tcttggacga cttttggaaa atctataaag aaggttaaac gattctcctc catctcgaaa
    24301 cgataagcta atttttcatg ttctaataga ctcttaacca caaagagccc cataccagac
    24361 cccttgacct tgcgactagc attgtcagaa aaagactggg ctagtttttc ttgttcctct
    24421 gagctacagc tattttcgat aaaaagttct ccttctcttt ctccaattcg aactaagcca
    24481 cctggaacag agtgcttaat ggcattgctg atgagattag aaagaatcaa cttcataact
    24541 gatgggttta gataagcctg ctgatgggtc aaactattgt ctatctggag ctctctttcc
    24601 tttgctagca aggcataatc tttgaccaga ttttgcgtca tctggaggag gtcaattgtt
    24661 tccctatcat ctcgcaattc ctgcacagaa gagagggaaa gtatctgcag aacatggtga
    24721 ttgagttcat ccacaatccc caaggcaact cccagatact ggtctctatc cttataacga
    24781 ccgatattct ctctcatatt ttcgattagg attttcaaac tagccagcgg tgttttcaat
    24841 tcatgagaag ctcctcgtag gaattcgacc ttcatcttct ccagctggag aatggcttca
    24901 ttcttttcat gcaagtccgc aataacagtc aagagatgct ggtagaggct attgatttgt
    24961 tccttgagat tacctatctc atccttagaa tccacgcgca atcgcacttg ggaatccagg
    25021 tccatcatcc gacgggtcac ccgcttgatt tccaaaatcg gtgcaacaat agtccgagcg
    25081 tagatgtagg ccaccaagag ggaaatcaga aaggaggcca gcaaggtata gggaagaaac
    25141 tggagactga tttgctccgc ttccttttgt aaatccatgg aagctagaaa ctggagaatc
    25201 atagtaccac cgtcttgcgt tttcacctcg cgctcctcaa taaagagaga ggttgtctgg
    25261 cggtctgtgt ccagaggaag actgtccttg acttctaact tgtcctcggt catctcacct
    25321 ttgacggtcc ccttgatatc actagtctgg gaatacaagt ctaacacttg ctcgatactc
    25381 tgcctatctt tcccttctag ggactgggca atggctgttg ccttttgacc aatggtttcc
    25441 tgacgatgac tcagataagt cgaaggaaaa agaaaataaa tagctaaatg aaggcagata
    25501 accagaacac taaatatcga gaaggtatag ataaatatct ttgcaaataa acctgttcgt
    25561 ttcattttcg ctccaattta taaccaacat tgcgcacagt gaggatacaa tccaagtcta
    25621 gctttttccg caattccttg atataaacat caataacacg gtcaaaggga acctcatctg
    25681 tcgctttcca gacggcatcg ataatctgag atcgagtcaa ggcccggcct tcatttttca
    25741 ctagatagtc cagaatttcc aactctttgg cattgatagg cacttcttgg cctgcgaggc
    25801 ttgcactgta gctttcaaag tccaccttgg tatccttgta agaaaagatt cgtcctgtat
    25861 cgtagtagcg cttgaaaatc gcgtccaccc tcacttttaa aagggagagg gagaaaggtt
    25921 tttccagata gccatctgcc aaagaggcaa aggcactcat cttgtattcc tcatcttgaa
    25981 aagctgtcaa catcaagaca ggaacctgac tggttttacg aatctcagct aggacttcta
    26041 agccgttgag cttgggcatc tggatatcca gtaaaaccag ggccacctca tagctagaaa
    26101 attgctccag agcttcctga ccgtccgctg cctcaatagt ttcatagcca caatccgtca
    26161 aataatcact gaccccctca cggatcatct cttcatcttc tacaattaaa attttcatac
    26221 tttaactgct ctctattttt tatttttctt agaataaata cctaccctat tttctattat
    26281 agtctcttgc tggccttttg tctgcaagca actgaccact agataaaacg ttgtgaaatt
    26341 cctttctcat aaattccata actttagtat attatattta agcactaaag tacaaagaaa
    26401 gcaactgaaa gcaatgattt tcaccactgc tttcggattt attttgaatt gttaaatagc
    26461 cattcctatc cactattctt gaatagaaac acaagatgca atctttattc tagactcatt
    26521 ttttcaaatt tattcaccat ccagcaagag ctcttttggt tgttttctaa ggagattgct
    26581 tgaagcaagc gccataacga gaaccactag aaccaaggca aggacaaaaa tgatgataaa
    26641 gtctgatgtc tgaatggaaa tgtctaggct cgacaaggtc ttgctaaagc catctacttc
    26701 tgcaccacca ccaaggttag aggcttgagc cgccttacta gcctgtttgg caacacctga
    26761 agtcacattg gcaaggacag tgtttccaat tgcacgggca gtgtaattag ctaggaagta
    26821 agcagaaact agagcaggga tagcaatcaa gatagattcg gtgatgaatt gacccaagat
    26881 acttgcctgc ttgaggccga tagagaggag aattcccact tccttgcgac gggcgttgat
    26941 ccaaaggctg agcaagaggg caaggaggag aactgagaag ctcaagctac cccagaagag
    27001 gaggttggcc atcttgtaca taccagagat agattgctca agagctgggt agttagagga
    27061 gctcttgacg agtgtgtagc tcttccagtt gataccactg atgccattca actctttcat
    27121 aacatcatcc aagttcttgt ctgctgttac aaagaaggtt gcgtccccat aaatggctgt
    27181 gtcttctgtg tatccataaa gttttgcagc agtgtgaatg tctgtaatag ctgtgttttc
    27241 gtaaagttct tgtgagtagg ttactgctga cttattatga ccatcaaaga gtcccttgat
    27301 tgtcacttca actgtttcct tggctccttt ttcattatct gcatcgtaga tattagagtc
    27361 cagtttaacc ttgtccccta ctttccagcc gtgtttggct gccaagtcct tgtgcaagag
    27421 gattttatcc ttgtcgtcgt tggttaagtg ctctccttcg actagtttat aagaaccaga
    27481 gacaaacttg tcttctttag aggagtcatt gacacctgta atcatcaagc tacttccaaa
    27541 acgcttggca cgatcagcag tgagattctt cttggtttct ggcgtttcaa tcaggtcata
    27601 tccagtcaaa tctccgatag cgttgatacg tttgacataa gactcaatgg ccttgttttc
    27661 ggtgattttt ttgatgtctt cacccttgat attcccagca ccacgaggcg ttccttggtt
    27721 gacgcgacga ttgatttgca tggagaagct attggtgata tttttaaagg tctcctgaga
    27781 agccttggca gtagctccct tgattgacaa gccgaccaaa ctcaagctcg ccatgaggag
    27841 aataatcagg aagatgacaa tcgatttgaa aaacttcctt gtaacatagg caaatgcgtt
    27901 gtgtaacata gattcccttt ctagattttg ttttaatcat tctattaaaa taagctcaaa
    27961 ttatttacta gtattgcgcg tttcagtcag tttcttatcc tttaattcaa gtgtaatatc
    28021 tgacgcttgt gccacttctt tactgtgagt tacgacaatc acacatttac ctgttttctg
    28081 ggcaagtgat ttgagtagtt cgacaatatc tccagcagtt ttaggatcca gatttcctgt
    28141 tggctcatca gctagaataa ctggagcttc tgagaccaaa ctgcgagcaa tggcaacacg
    28201 ttgctgttga ccacctgata actggagaac attccgcttg atctggcttt catccaaacc
    28261 aagctcaaga agtgtattct tgcttgcctt tttgttgacc aatcggatat tttccagcgg
    28321 agaaagataa tctatcaagt tataattttg aaagaccagg gaaatatggt gcatgcgatg
    28381 gtaagaatag cccttcttac gaatatcctc tccttgaaaa aggatagaac cttcaacagg
    28441 actatctaga ccagcaagta gggacaagag tgtggatttt cctgctcctg actccccaat
    28501 aatactgtaa aattttccgg gttcaaaatt ataattgatc tgatatagga ctgcttcagc
    28561 agtattctta taacggtagg taacatcttg taattgtaat aaagtcatga tttctccttc
    28621 ttaactaata gatgataaaa tttctttcgg tgattttcta aataagaata ggaaacaaag
    28681 ggctacagat aagcaactaa gcagaactag aaaaacatag gattctgcaa aagataagat
    28741 gctagttgat aaactgcttg ctttggctag tgtatcttgt aagcttgcct gatctccact
    28801 tgctagtaga gtttggagta ggtaagttgt gattgcgttt cctgcaacaa atgctggaag
    28861 caaagctcca agagatacca aaactacctc taaacagaat tgtaggaaga tcgagctctt
    28921 gccttttcca agtgcaagta aaatccccac ttcatagacc cgttctctca accagagaga
    28981 caaaaccaga attaaggctc cagctcctgc tatcaacatc ccataaagga agatggtcag
    29041 gaaggtttgg aaagttgcaa ctgagtcttt gatttgttca aaagccttgt tttccttttc
    29101 gacttggtag ccttgatttt ccaaagccaa gttttctacc tgcttcatga gtccgtccat
    29161 ttccttagga ttttctacat agaagcgtgc tgcactgact tgagcttcac tattgcccaa
    29221 aagggtttgg ctactttcat agtctgtaaa gacttgattt tcactgaagt cagaagacaa
    29281 gcctgtgaat ttctcttgtt ttttaccaga aaagatgccg ataatctcaa actctactgt
    29341 ttgtcctttt ccagattcag actgaccagc atccaagcca atcttgtcat gaagcgaaag
    29401 accgttcttc ttagccaatt cttcgtggat aaggattttc ttggaatccc ctttttgaag
    29461 gtgtcgccct tcttttagat tgaaagccga actggtaaag gttacatcct tggatgaatc
    29521 ctcaagagcc gttaagctaa ccaagttatt gtctgcagct gataaatcat cacgctccac
    29581 gctctgctcg ccagtcactg cttccttgtc ttttagtttt gcgaccgtct caagttcagg
    29641 agagacattt tccagcccct taatcttgct tacagatgct aggtctgaca acttgaatgt
    29701 ctgaccattc tctatcttct taatagaaaa agatgtattg agtgatttat aaagattgct
    29761 ttctactgtt ttgttggact tcatcagagt caaacaggct gaaattccgg ccaataagac
    29821 caataaaatc agaaataaaa taaaacttct cagtcgcttt ctgctgacat aagcccaaga
    29881 tctttggatt ggattcattt gtcacctcca tatttgtaag actattataa aacccaaata
    29941 tgaaatgttt atgaaatacg aaaaaaaaat atcgagtagg ggataatctc tagcccctct
    30001 cacaccacca tacgtgccgt tcggcatacg gcggttcaac taacttttaa cgcatgtcgt
    30061 tcaaggtaat aatccaaaca cgaaaccagt ccacgttttt caaggactgg ttttgatata
    30121 gcacgtttaa gtaccgactt ctgagctact atagtagatt gaaactagaa tagtacacct
    30181 ctacttctaa aatattgtta gaaatcgatt tgactgtcct gaacgattcg tcctattctt
    30241 atttcatttt actataattg atagtggtcg ccccagccag ataccttatc tgctatccat
    30301 ttaggaaccc ctaacttaag caatccccat aatcgtctcg atttcttctt ccattgcttc
    30361 cagataatca ctcgtaggcg agtacgcaag cgctcatcta tgctagtgac tatacttttc
    30421 atatttataa ttcattcctt tcgtttcact caaggcacaa cacagaatga aaaagtgttg
    30481 tgatctttat tttgttttat aataatagtg agaaagccta tcactactac aaatcacggg
    30541 gaggtgaata agtgagtggt acagccacta cctcgcatat tttgtcacat catttaacgg
    30601 tacataataa gttgtaccat ctgaataagt tgctacaata tcatttgcat gctctccttc
    30661 acctttagca aaggttggag ctcctgctgg atgattttta tttgcctctt tcaatttttc
    30721 aataatggca ttttttctgt atcttttata ttatcaggat ttttcactaa gattttgtct
    30781 ggatatgtcg gtttagcaga aacaattttt actgttattt cttttttatt cgaagcactt
    30841 gtccagtttc cagcattatc tttagcattt aattttacag taattcctga actaggaact
    30901 tcagtagcag gttgattatc aacattattc aactttaatt tcaaaagagc tgttgcatca
    30961 gacgttttat caatcgttat atataatgat gaattgttat tataaccagt ttcttcatat
    31021 ttagctgttt gtgagctact tgaaacagaa ctgaaattat gcccactacc tccctgatta
    31081 tcttcaatgc ttacgtctaa atgaacttcc ccactattat ttggcttagc aacaactgtt
    31141 atagtaaaat aacataaaat ttgcataaat agattaggta aatcaaagca acttctagga
    31201 atgttttagc agtcacagtg tactttccca gcatcaagcc actataactc tgcacataaa
    31261 aatggagaag atggcaatcc tcttctccaa atattaactt ctttacaaac caactatagt
    31321 tgacaaagaa cctaaaatca attgataaca caaggtcagg tcggtcaact ctttcaactg
    31381 aagccctgtc aactcttccc atttatcaat cttgtattgg agagaattgc ggtgcagata
    31441 gagttgctgg gctgttttag tgagaacagc actattttcc caaagagaga gaatgatttc
    31501 ctgaatctga tcttgatcca aaatcatctg gtgtagacat tctttaattg gcttcaagtc
    31561 cacgagtctt tctcccatac tccaaagata gagctgagaa aaagtatgaa caccttggtg
    31621 accctgacgc caccatgtct tgaacaaatc ccgctcagct ttgattaagt ctgatagggc
    31681 ttgatgtcct gtctgagacc aaacctgacc caacatgata gaaagacgaa gtccaaagtc
    31741 atactcaacc gcttcaatcg tatcacttaa aatatctctt acagaagtgt atttgtcttg
    31801 ttgaagcacg aaaacataat cctgagctcc gacctgtagc actgtctgac aattcggaaa
    31861 aagagtccgc atcatatcta gccaagaagc cagattttcc tgctgaaaat aagaaagatg
    31921 gcaataaacc aactgaatct ttttaaaaac ttgcggtgcc tgtcccttgc cttcaaccag
    31981 ataggaatac caagggttta gcgaacgagc ctgctcctgc tgggtcaaaa gggcaaccaa
    32041 ctgcttttca cgctcgctga gcccagcttc ctccagcaaa atccactgct gagaagctaa
    32101 agggagcgtg agatagccct ctttctctac tggttggtct gaaatccgag cctcaggaaa
    32161 ccagtcttgt agttcttttg ccctcatgtt ctagccctcc actttttgga tgcaccatga
    32221 aaccaaactc tcaagacgtt ccagattctc agtcatatgg agatagccca taaccgcttc
    32281 aaatcccgtg gacatacgat aagtcacgac atctgcattt ttagcctttg tgtggctatt
    32341 ggtattgcgg ccacgtttat agatttcttc ttctttttcc gttaggacct gctcctccaa
    32401 catgagagca atcaggcgag cctgagcctt ggctgacaca tacttggttg cttcttgatg
    32461 gagtttattg ggtttggtca tacctttgag gatgaggtga cggcgaatat acatagaata
    32521 caccgcatcc ccctcaaagg ctagcgcaat cccgttaatg agattgacat caatcacgtg
    32581 tccacctcac tccatctttt gtatccaata gtttaattcc ttgagtaacc aattggtcac
    32641 ggatttggtc tgctgtctca aagtcacgat tggcacgcgc ctcttggcgt ttttgaatca
    32701 agtcttcaat ctctgcatcc aaaacttcct caacaaagac aattccaaaa atttctaaca
    32761 tatctgcaag agcttgcttg acacttgcat catagttccc tgagttgatc catttggcca
    32821 tttcaaagac aactgtgata ccgttggcag cattaaaatc ttcatccata gctgctacaa
    32881 acttatcttt aaagttttgt aactcttggg catccacgtt tcctgtaaat ggttgttcgt
    32941 aagtattctt cagatacttg agattggtct cggcatcgcg aactgccttt tccgtgaagt
    33001 tgataggctt acggtagtgc tgggtcgcaa agaagaaacg aagtacttgc ccatcaagag
    33061 ttttaagggc atcgtgtacc gtaatgaagt tacccaagga cttagacatt ttgacattgt
    33121 cgatattgac aaagccattg tgcatccagt agttagcaaa agccttgcct gttttagctt
    33181 cagattgggc aatttcattg gtgtggtgtg gaaactctag gtcagctcca ccaccgtgga
    33241 tatcaatggt atcacctaaa atctctgtcg acatgactga acactcaata tgccaacccg
    33301 gacgtccagg tccccaagga ctatcccaag aaatctcacc tggtttggaa gatttccata
    33361 gagcaaagtc tacaggattt tccttacgag ccgtttcttc atcggtacga cctgaagcac
    33421 ctagctccaa atcttccaag gttttattag ccaatttagc atagttgtgg gatttttcta
    33481 cacggaaata gacatcccct tgactctcat aggcaaagcc tttctcgatc aagtcttcca
    33541 caaaacggat gatgtctgcc ataaactcca ctacacgcgg atggcgagtc gcaggtttca
    33601 cgcctaaggc cgtcacatcc tcacgaaagg cagcgatgta cttatccgca acctcctgag
    33661 gtgtgatgcc ttcttccctg gcacggttga taatcttatc atccacatct gtaaaattgg
    33721 aaatataggc aaccttatac ccacggtact caaaatagcg acgaatcgta tcaaaagcta
    33781 ccgtcgaacg ggcgtttccc acgtgaatat agttgtacac ggttggccca caaacataca
    33841 tcttgatctt gccgtcctca atcgggacaa attctcgcaa atcacgagac atggtgtcat
    33901 agattttaat cataaatcat aatcaggaaa gctaaaatcc aagaactgtt agtttcatca
    33961 ctaaactaag agctcaagta aatttcagtc cgaatgtctc tacacttcgg aatcccttgc
    34021 tcctttctca ttcagataaa ccacctgtgt ctgtttgaca aagccaattt tttcatacaa
    34081 acgtttggca cctacattgc tatcttccac tgcaatctga aattccttgt cattttgctc
    34141 aattagttgg ttgacgaggg attttgctaa gtagcttcca tagcctttcc cacgttcagg
    34201 ttccgatatt gctaaaccgt agaagtaatt cgtattagtc gataaatcta ccgtgcaagt
    34261 cccaataacc tgaccgtctt ttaacaaaat atataagcga ctttctggat ccttcagagc
    34321 ttcagcgaca tatctatcca caacttctct cgattcatgt tcctctgaaa atgcctgaaa
    34381 ttttaattga ctaatttgat cctgatacga actatctgct aacaaaactt caagatggga
    34441 aacatttgct aacggataag gtcttctatc cttacctaac caagtttctg tctcttcatc
    34501 ctcgattagt ccccagttac tggcaaagtc aggatgattc tctaaaaaaa tacgttctgt
    34561 ctgaaaagtg actgaccgaa tggggaaaga agctgtttct ctctcaaaac tagtaaacaa
    34621 tgcacgcgca atcccctgac ggcgatgacc tggatgaacc aatatcgtca cttctacatc
    34681 ttggtcatct gcatagacag ttaataaacc aacaagtttg cctttttcat aataaaggaa
    34741 aaaggcgggc atgtttgggt caaaattaag catgttagag agatagggat cgcgataggt
    34801 accgtcatag ttttggcaac agttaattac ttttttcgcc tcagatagct cctcttggct
    34861 taacttgttt cttgcttgaa tcatataggt atcctctaca aaccagacga tctgtgactg
    34921 gcatctttag cctgctcgag tttattgaca taatactccc gtttttcttc gacttcgtga
    34981 ataacaggct catctttctt accatgaaga cggacaatct tggccggaat accgacaacc
    35041 gtcacatcac taggtacatc tgctacgaca actgctgcag caccgacctt ggcattttca
    35101 ccaatttcca caggcccgat aacttgggca tgggctgata tgagggctcc ctttcgtaca
    35161 gtcggatggc gtttgccaca gtctttccct gttcccccga gagtcactcc gtgatagaga
    35221 agaacgcctt tttcaacaat cgctgtctct ccaatcacca gaccagaacc atggtcaata
    35281 aagacacctg aatcaatctg ggctcctgga tgaatctcaa tctgagtcca aaagcgccaa
    35341 aactgactgt gcatacgagc taagagtttg aagtcgtact tccagagaaa atgcgagaga
    35401 cggtgggccg ccaaggcctt gacacctgga taagtcagca aaacctccaa agtggtgcgg
    35461 gccgctggat cattttcttt tacgatatca atggtttcgt gccaccaccc catacatttc
    35521 tccttttctt actctgaatc ttttggtgtt tctgtaaatt ctttcttagg tttgtgatcc
    35581 ttgtgatgac gtgggcggtg agggcgctca gacttttcac ctttttcatc atgctcaggt
    35641 tttggcggac gaggtagaag agccttcata gaggcatcga tacggccttt ttcatcaatc
    35701 ttgataacct taacatcaac ttcatccccg atttctacca aatcctctac acgattggta
    35761 cgagtccaag ccatctcaga gatatgaaca agggcatctg tcttatcaaa gaggttaaca
    35821 aaggcaccaa atttctcgat acgaacgact ttagcacggt aaacttcatc cactttggct
    35881 tcacgaacca aaccagcaat aatttctttg gcacggttaa tagcatcttg gtcactagag
    35941 tagatagaca catttccttc ttcgtctata tcaatcttaa cacctgtttc agcgataatc
    36001 ttgtcgatgg tttctccacc cttaccgatg acaatcttaa tcttgtccac atcaatcttg
    36061 atcgtatcaa ttttcggagc agttggagcc aattctggac gaacttctgg aatggttgct
    36121 tcaatgacat caaggatttc aaaacgcgct ttcttggctt gagcaagagc ctccgtcaag
    36181 atttctgcag taatcccttg aatcttgata tccatttgaa gggctgtaat cccatcacga
    36241 gtacctgcaa ccttgaagtc catatctcca aagtgatctt ccaaaccttg gatatctgtc
    36301 aatactgtgt agttatttcc atctgagata agtcccatag caataccagc tactggcgcc
    36361 ttgattggca caccaccagt cataagggca agagttcccg cacagataga agcttgagat
    36421 gaagaaccgt ttgattccaa aacttctgct actagacgga tagcgtatgg gaattcttcc
    36481 aagcttggca agacttgagc aagagcacgc tcaccaaggg caccgtgacc gatttcacga
    36541 cgacctggcg caccgtaacg acctgtttcc cctacagaat attgagggaa gttatagtgg
    36601 tgcataaagc gtttcttgta ctctggatcc aaaccatcaa tgatttgagt ttctcccatc
    36661 ggagccaagg tcaagactga aagagcttga gtttgcccac gagtaaagag acctgaacca
    36721 tgtacacgag gaaggaagtc aacaaccgca tccaaaggac ggatttcatc gaccttacga
    36781 ccatcaggac gcaccttgtc ttctgtaatt aaacgtcgca cttctgcgtg ttccatttgt
    36841 tccaagattt cagccacatc acgcataata cggtcaaatt cttcgtggtt cgcatatttt
    36901 tcttcgtaaa cggcagtcac ttggtctttc actgcttgag ttgcagcttc acgggccaat
    36961 ttctcttcta cttgaactgc cttttggagg tcactgttgt aggctgcaat gatttcagct
    37021 tgcaattcag catccacgtg aagcaattcc acttctgctt tttctttacc gacagcagca
    37081 acgatttctt cttggaaggc aatcaattct ttgacagctt cgtgcccttt aagaagcgct
    37141 tccaacatga tttcttctga caattctttg gcaccagact ctaccatgtt gatagcgtgc
    37201 ttggttccag ctactgtcaa ttcaagaaga gattgctctg cttgttcttg acttgggttg
    37261 atgatgattt ggccatctac atatcccact tgtaccccag caattggtcc gtcaaatgga
    37321 atatctgaaa tagacagtgc caaagatgaa ccaaacatag cagccattgg tgcagatgca
    37381 ttttcatcat aagaaagcac tgtattgatg acttggactt cattacggaa accttccgca
    37441 aacataggac gaatcggacg gtcaatcaaa cgcgctgtca aggtcgcatc tgttgaagga
    37501 cgtccttcac gtttcataaa gccaccagga aacttcccag ccgcatacat tttttcttcg
    37561 tagttgactt ggagtgggaa gaaatcccca gttgccattt tcttagacat aacggcagca
    37621 gtcaagacag ttgactcacc gtaacgtacg acaacagagc catttgcttg cttagcaacc
    37681 tgaccagttt ctacaattaa ctcacgaccc gcaaaagtcg tttgaaacac ttgttttgcc
    37741 attttaatcc cctttggatt gatgaaatta tacgccttgc ctacaaagat caagatacca
    37801 aggacgtcaa aagcaaagta aaaataggaa actgacgaag tcttcgatga agacaagaca
    37861 gtttatcttt tttacacagc ttttcggccg tgttcaatta cacaagatat tttggacggt
    37921 tcggcttgcc gaacatttct gtagaaaaat aggaaggtga cgtcgcactc gacgagtgct
    37981 aggaagctta tcttttttcc taagaaatga gaccaaaatt caagtcatca agataccaag
    38041 ccgtcaagca actcaaagga aaataggaaa tcgaacgacg gagcgactgc tcctagggag
    38101 atttatcttt ttccacagag ttgtaggcaa gttcagtttt caagatacat cattagaaag
    38161 gtttaatact aaagtatcta aagctttcac gctaatcgct atcgggcgat tagctaaatg
    38221 ctttactaac tctctcgtca aataacatcg atttgactca ctcgtgtcgt taaatcttac
    38281 agtttaaatg cattgtatta tttaatacct tcatctttgt atcaagtacg tacagaattt
    38341 attttatcat atttttctta aaaagtgagg tctttaccat taaaaaggaa ccattcccct
    38401 cacctgagaa gaatggtttg cttttattat cctagagact ggtgattaaa caaggcatgg
    38461 gttgcttgat ggatgtattt tgctgtatca gcattattca tcgtatagag atgcacaccg
    38521 gcaacatcct gagttaccaa gtccacgatt tggtccactg cataggcaag tcctgctgct
    38581 ctgagcgact cagggtcatg ctcatacttg tctaagatgg ctttaaattt gcgtggaaga
    38641 tggatattct cacaagtctt caagagtcgg agagcctgat ttcgattcag aattggcata
    38701 attcctgcat gaatgggaac atcaatccca gccaaaatac acttgtcctg aaaatcatag
    38761 aagcgctcat tatcaaagaa gagctgagtt acgaggctcg aacagcctgc atccactttc
    38821 ttcttaagat tttgaatatc tgaaatctga tttggcgaat ctggatgccc ttctggatag
    38881 caagctccaa taatatcaaa gtgaggggct tgttccttga taaactcaat caagtcggtt
    38941 gcatagcgga aatccttttg tggttctacg tctggaataa tatccccacg aagagccaag
    39001 attttctgca ccccaacttt gtccaagtca gcaatagttt cagcaacctt gtccttagtt
    39061 agataaatag ctggcaagtg ggcaatggtc ggaatcgcca agtcattttg gataaagtca
    39121 gccaaacgaa ccgtcgtttc cttgatatta aatttattat tgctggcagt tacactgata
    39181 aaatggggag ccaactcctg catatcctgc aaggctgaaa taatgttacc attacccacg
    39241 gctgggtttg gagggaacac ttcaaatgag agtgacggtg tttggcgtga catatgtaat
    39301 aaccttttct agttgatttc tttttgaaca accactgtat ggagagaaat ccaatcttac
    39361 aatttctcac gcgcagcttt agctgcttca acaaggcgga tcaagctttc ttttgtttct
    39421 gggataccac gtgttttcaa accacagtca gggttgatcc aaactttctt gcttggcact
    39481 ttagcaagga tggcttcgat tgtgttgtcg atttcgcctt catttggtac acgaggtgag
    39541 tggatatcgt aaaccccagg tcccacttct gtttggaagt ttttcgcttt gagttcgtcc
    39601 aagatttcaa ggtttgaacg gctagcttca aaggaaataa cgtctgcatc catgttatcg
    39661 atagctggga tgatatctgt aaattctgag taacacatgt gagtgtggat ttgtgtgtct
    39721 ggcgctactg ttgagtgtac caagcggaag gcaggaatag cccagtcaag gtagtcttcg
    39781 taccagtcgc tacggcggag tggcaatttt tcacgaagag cagcctcgtc gatttggatg
    39841 attttcacac cagcagcttc aaggtcaagt acttcatcct tgatagcaag ggcgatttga
    39901 agagttgaat ccttgataga gatgtcttca cgtgggaatg accagttaag gatggtaaca
    39961 ggtccagtca acataccttt aacaggtttg tttgtacgac tttgtgcata gctagaccat
    40021 ttaacagtga tagagttaag acgagtgaca tcaccccaga tgattggtgg ttttacccca
    40081 cgcataccgt atgattgtac ccatccattt ttagagaaga ggtatcctga caagttttga
    40141 ccgaagtact caaccatgtc attacgctca aattcaccgt gaacaaggac atcaaagtca
    40201 atatcttctt gccacttgat ccattcgtca atcgtttcag caaggaaagc atcgtactct
    40261 ttttgagaca attcaccttt acggtaagcc aaacgtttgg cacgaacttc ttttgtttga
    40321 gggaatgaac caatcgttgt tgttggaaga gctggaagtt tgaaagcttc ttcttggata
    40381 gcttcacgtt ctgcaaaggc tggcaaacga gtgtagtctg cgtctgtcaa gccagcgata
    40441 cgcgcacgaa gttcagcatt ttcaccaaca cgctcagtcg caaagagttc tttgttggct
    40501 gcaagagctt ctgaaccttg accattgcgg atagcatcca agtcacggat ttcatccaat
    40561 ttttcaactg caaaggcaaa gtggttcaag agtgctggtt caaattcttc attagcagtt
    40621 gtaaatggca catgaagaag tgagcaagag cttgtcaaaa cgatgttttc agctgggatt
    40681 tgctcaagaa cagccaagct cttttcgtag ttgttgcgcc agatgttttt accattgaca
    40741 atacctacat agagagtctt gtcagctggg aagccacctt taacgagttc aagagttttc
    40801 ttaccttcaa caaagtcaag accgatagca tctactggca agtttacaag gtcagcgtat
    40861 acgtcacgaa catcaccgaa ataagtttga agcaagactt caagaccttt tttgtcagcc
    40921 aagagtttgt tgtaaaggtt caagaagaga gctttttctt cagctgtcaa gtcttttaca
    40981 agagccgctt catccaattg gatgcgagtc gcaccaagtt cagccaattt agcaaaaact
    41041 tcttggtaag caaccactaa gctatctacg aagtcgtctg ctttcacgcc ttcttcaaag
    41101 tctgacaatt gaaggaaagt gaagggacct acaagaacag gacgagtgtt caatccaagt
    41161 tctttggctt cttggaactc atcgaaaatc ttgtgaccag ccaattttac ttgagtgtct
    41221 ttttcaaatt taggaacgat gtagtggtag ttagtgttga accatttctt cattggaagg
    41281 gcgcgaacgt cccctttttc tccctggtaa ccacgtccca aagcgaagta gcgctcaagg
    41341 tcagacaagt ccaagttttg aacggatgca ggcaccacgt tgaaaaggaa agccgcatct
    41401 aggaagttat catagtgaga aaagtcattt gatggaattt cagtgatgcc tttttctttg
    41461 acaatgttcc agtgtttagc acgcaagtct tttgctgctg ctaaaagttc ttcttctgag
    41521 atttcttttc taaagtattt ttcagttgta aattttaatt cacggaattc gcccaaacga
    41581 gggaaaccga tgattgtagt tgacatgatg tgtcctccaa aatttgttgt tgaaactatc
    41641 ttaacagaaa agaaagcgtc tgtataattg taaaaaatta gggtttgata tagtttgaaa
    41701 ctatatatct gtttcggaca aaagaaaaag acttgaagca aacgtctcaa atcctttgta
    41761 attcttactt tacagctata ttccaattag aatactaaaa catgttatta gtaattctta
    41821 taagtgacta tgacctgtta ttagaaaaga ctataactga ttctagtcaa ctttttccct
    41881 gttcaagtgg gacgattgct agtgtctttc ctaaactggc taggactttt aagactgtat
    41941 ccaactgagg actagtcttt cctgtctcca tcctagctat gacaggctgg cttattccac
    42001 tgacttcttc cagctttttc tgactgattc cttgttcata cctagcctca atcaactcgc
    42061 tcatgatagc cactcgcata tcactttcaa ggatttcctc cttgctaaag agctcagatg
    42121 gacatccttc caattactcc caatagcact attcttcatc acttaaccct ctttttttta
    42181 cgtctatgta tttttaaaaa aatgagcgaa ttatgattcg atagattgac cagtgggttt
    42241 aaagttggtg ctagcctatt tcttaagcga ttttcctttt ctaggataaa gcagttcctg
    42301 cttgcttaac cccaattttc cacgatgaat ccaatagtaa atggttgaaa ttcccacgtt
    42361 aaccccttta gccatcacca tcatttcagg cgaaaatttt tggttatgtt tttggttatg
    42421 tatagtggag aatcttttcc tttagtttct taagactgtt gagcgtagtc ggcagaataa
    42481 atctctttga agcgcccttt tccaagacat tgtcggactg tcccacgctt gatttcagtg
    42541 tggatagttt gaggagcttt tccaagtaga gaggcaattt ctctatttga ttttccttct
    42601 tttttccatc gttcgattaa gcgacggcta tcgattgtca aatgtttgcc ttttgtagta
    42661 taattgtctt gcatttctgt gccttttaat catttcaatc ttaaattgga ctttttttac
    42721 ttgggttgta cttaatctat gaggaagaca agaaaaagaa tatcaatcaa gtaaagtcac
    42781 aaagtcacat tagctccgag caaccattgc aaattgaggt actcacacaa tgattaaaac
    42841 atttctctct gccctttcgg tcattctctt ttctatccct atcataactt attctttttt
    42901 cccatcttct aatcttaaca tttggctatc tacccaacct atcttggcac agatttatgc
    42961 cttcccctta gctactgcaa ctatggctgc tattttaagt ttcgtatttt tttccctatc
    43021 tttttacaag aaaaataaac aaatacggtt ttactctggc attttgctct tactatcgct
    43081 catattacta ttattcggaa cagataaaac cctttcttct gcatcaaata agactaaaac
    43141 cttaaaatta gtaacttgga acgtcgctaa tcaaatagaa gcacaacata ttgagcgaat
    43201 ttttagccat tttgacgccg atatggctat attccctgaa ctagctacca atatcagagg
    43261 tgagcaagaa aaccagagaa tcaaactatt gtttcatcaa gttggacttt ctatggccaa
    43321 ctatgatatt ttcacttctc cacctaccaa tagtggaata gctcctgtga ctgtgattgt
    43381 caagaaaagt tatggtttct atacagaagc taaaactttt catacaacac ggttcgggac
    43441 aattgtatta cattcgagaa aacaaaatat accagatatc attgccttgc atactgctcc
    43501 tcctctgcca ggtttaatgg aaatctggaa gcaagactta aacatcattc ataatcaatt
    43561 ggcttcaaaa tatccaaagg ctattattgc aggtgatttt aatgcaacta tgcgtcatgg
    43621 agcacttgca aaaataagct ctcataggga cgcattaaat gtactgccac cttttgaaag
    43681 aggaacttgg aatagccaaa gtccaaaact ttttaatgca acaatagatc atattttatt
    43741 gcctaaaaac cactactatg ttaaagattt agacattgta agttttcaaa actctgatca
    43801 tagatgtatt tttacagaaa tcacatttta attattttat ataaaatcac ccctctagtg
    43861 ttcataaact agagggggaa tttgtatcat actatcgttt aacgcacttc tgcattgact
    43921 ttttcttcga gcgatgcttg gattttttcc atatagcgtg cgacttcttc gtccgttaag
    43981 ctatcttctg gattttggaa ggtcaagcta taagccattg acttcatacc aagtcccaat
    44041 ttctcacctg agaagacgtc aaagagtttg atatctgtca aacgtttcac gccggcagct
    44101 tggatagcat ctacaacttc ttgatgagtc acttctgcct tgaggagaag ggcaacgtca
    44161 cggctgactg ccgggaattt ggtgatttct acaaatggag tcgctggctg aagcgcagct
    44221 tcgatagctg aaaggttaag ctcagccaca tacgtttctg gaatatcgta agccttggca
    44281 gtgactggat gcacttggcc aaggaaacca agaacttggt caccgaatga aatcacggct
    44341 gtacgacctg gatgaaggct agcgatttca gatgttgctg tataggttac ttggagtccc
    44401 aaacgagtaa atagggcttc aaggattccc ttagcataga agaaatcaac tggaactgct
    44461 gctgtttgga aatctttttc agcaaccaag cctgtcaagg caaaggcaaa actgttgatt
    44521 tcatttggaa gttcttcttt tggattacct gtttgttcaa agacttttcc aatctcgtaa
    44581 agggccaagt ttttattctt acgagccacg ttgtaggcaa cggtatcaag gatacctgaa
    44641 atcatatttt gacggaggac tgaacgatcc acagtcattg gccacatgag ttccgtaagg
    44701 ttacttggtt gagccgtaaa ctcaactgct ttttcaggag ttgttagagt ataggtgatg
    44761 atttctgtca aacctgctcc ttcagcaata gtacgaactt gacggcggag tttttgtgtg
    44821 gctgtcaatt cacctgctgt accatcgtct tttggtagac tagttggcaa gcggtcataa
    44881 ccatagatac gagcaatttc ttcaaagagg tcagcttcga ttgtgatatc ccaacgacga
    44941 cgtgggactc tgactgtaaa gctgtctgca tttccagaaa gaccaaagcc aagacgacgg
    45001 aagacgtctt ctacatcagc ataagacagc tcagttccga ggacacgatt aacatcagca
    45061 agggttgaag aaacttctac atctgaagta tcaagctcac ccgctgaaac gatgccctta
    45121 cgcaccgtcg cacctgcaag ttccgcaatc aggctagctg ccgcatcaag ggcttcatta
    45181 actgttgcca cattaattcc tttttcaaag cgagaagatg actcagaacg aaggttcagg
    45241 cgaccacttg tcttacggat agatttgcca ttgaaaacag cagcttcaag gacaacacga
    45301 ctagattttt cagagatttc tgttgcttga ccacccatga cacctgcaag ggctactggc
    45361 ttgtctgcga cagtgatgac taggtcattc acgtccaagt cacgttcttc accgtccaag
    45421 gtcaccaatt tttcaccagc acgcgcttca cgcacacgga tgtcagtccc ttcaaagtta
    45481 tccaagtcaa aggcatgcat tggttgacca aaatagagca ggatgtagtt ggtcacgtcc
    45541 actacgttat tgatgggacg gattccttcg ttcatgagaa gattttgcaa ccattgtgga
    45601 cttggtgcga tggtcacatt gtccaagata cgagctgcat agtaaggcgc cttgtctgtc
    45661 tcaatgctga cagaaagggc atctgccgca gcttcattag tttctgttag agtaaattct
    45721 ttaaagttga ctgccttgtc atagatggct gccacttcgt gagccactcc acacatagaa
    45781 agggcatctg cacggtttgg tgtgatggaa agttcgatga tttcatcatc caagtctagg
    45841 taagaaaaga cttcctcacc tggcacggca tcttcaggca agatttggat gccatctgcg
    45901 aattccttag gcacaactga gtcagaaatt cccaattcac caagtgaaca gatcattcca
    45961 agtgactcca aaccacggat ttttcctttt ttgattttgt agttatcagc gatacgagct
    46021 cctggaagag ccaccatgac cttgatccca gcacgcacat ttggggcacc acaaacgatc
    46081 tgacgctctt cttcgccaac gttaacctga caaacatgga ggtgagtctc tggcacatct
    46141 tcgcaagaca agacctcacc gacgacaatt tttgagagac cagcagctgg tgattcgaca
    46201 ccctctacct cgattcctgt agttgacatt ttttcagcca actcttgtga tggcacatca
    46261 atgtccacca attcttttaa ccatttataa gatataagca taatttagtt ctccagaatg
    46321 accattgcca cactggttct tttcctttcc tatcatttca atagaagaat cctcttctta
    46381 ccttaatttc tttctcagta accaatccgt atctactttt tgaccaacca taaaatgatg
    46441 ttggctaaat ttttcaaaac catatcgatt ataaaacgct tgagcttttg tattatgctc
    46501 ccaaacacct agccaagccc aagaaaaact attttttgta gcaagttcaa gtgcgaattc
    46561 aaacagttgc ttacctagtc caaatccttg gaatttttgt agcacataga ggcgttgaat
    46621 ttcaaaagcg tcctctaatt ctctctcagt ttgagcactt ccccagttga ctttgagaaa
    46681 accagctatc tcctcctcat gcataatgaa ataggtttca gagtcaggat ttcccaactc
    46741 agttgacaaa gttttcagac tataagcctc ttcaaagtat tcctgtaact gctcttccgt
    46801 attatcatac gcaaaggttt cacgaaaggt ttgtttggca attttagcca acacctcaac
    46861 atctgccatt tctacttttc taatcattat ttaaactgtt ctgagaagcg gacatctcct
    46921 tggtagaatc cacggatatc gttgattcca taacggagca tagctacacg ctcttgtcca
    46981 agaccaaagg caaagccaga gtatacagtc gcatcgatac cactcatttc aaggacacgt
    47041 gggtgaacca taccggcccc cataatttcg atccaacctg ttttcttaca tacattacag
    47101 ccttctccac cacacttgaa gcaagaaaca tccacctcaa cagatggctc tgtgaatggg
    47161 aagtaagatg gacgcaaacg aatttgacgc tcttcaccaa acattttttg gacaatcaac
    47221 tgaagcgttc cttgaagatc agccatagag atatttttcc caactaccaa gccttcgatt
    47281 tggtggaatt ggtgactgtg ggtcgcatcg tccgtatcgc gacggaagac acgccctggc
    47341 gagatcatct tcaaaggacc tttagaaaaa tcatgggcat ccatagcacg cgcctgaact
    47401 ggagacgtgt gggtacggag caagatttct tcagtgatat agaaagtatc ctgcatatca
    47461 cgagctgggt ggtcttttgg aaggttcata cgttcaaagt tatagtagtc ttgctccact
    47521 tcaaaaccat ccacgacttg ataacccata ccgatgaaga tatcttcgat ttcttcactg
    47581 gtttgtgtca aaacgtgacg gtgaccagtc gcaactggac gacctggaag cgtcacatct
    47641 atactctcgc tagccagttg agccgcgact ttcttttctt ccaagagctt agctgtttct
    47701 tcaaaagcag cagtcaagac atcacgagct tcattgacgt gtttcccgat gattggacgc
    47761 atctcagcag aaacatcttt catccctttg aggatttcag tgagcgaacc ctttttacca
    47821 aggacagaga cacgcaaatc ttgcatctct ttttcatttc cagcagtaat ctgcttcaag
    47881 ctagccagcg tttcttcgcg aagcgctttt aattgttctt caatagttga catatttcct
    47941 ccatcagtct ctcgtagata aaaagaaaac cacatgccaa aaactccact cggagcgttg
    48001 acacgcggta ccatccgttt tcatctgaca agtcagacct tcatttctaa atccatgcgc
    48061 aagtgaattc acccagcttt catatagaga gcttgcagtc acggctctcc tccctgatat
    48121 acttcccttg ggctactagt ctttcagatt cctattcaat tactacttag tttatcagat
    48181 ttttaccatt cttgcaagac ctatcttact tctgcttgtt agcttattct tatctaa
//
LOCUS       DBEJKC010000008        46539 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.008, whole genome shotgun sequence.
ACCESSION   DBEJKC010000008 DBEJKC010000000
VERSION     DBEJKC010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 46539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46539
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.008"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(612..1025)
                     /gene="ndk"
                     /locus_tag="ACL3G6_000457"
     CDS             complement(612..1025)
                     /gene="ndk"
                     /locus_tag="ACL3G6_000457"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HGR0545040.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(1136..4813)
                     /gene="rpoC"
                     /locus_tag="ACL3G6_000458"
     CDS             complement(1136..4813)
                     /gene="rpoC"
                     /locus_tag="ACL3G6_000458"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HGR0545041.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(4846..8457)
                     /gene="rpoB"
                     /locus_tag="ACL3G6_000459"
     CDS             complement(4846..8457)
                     /gene="rpoB"
                     /locus_tag="ACL3G6_000459"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGR0545042.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            8873..8943
                     /locus_tag="ACL3G6_000460"
     tRNA            8873..8943
                     /locus_tag="ACL3G6_000460"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8905..8907,aa:Cys,seq:gca)
     gene            complement(9141..10472)
                     /locus_tag="ACL3G6_000461"
     CDS             complement(9141..10472)
                     /locus_tag="ACL3G6_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HGR0545043.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(10763..11587)
                     /gene="endA"
                     /locus_tag="ACL3G6_000462"
     CDS             complement(10763..11587)
                     /gene="endA"
                     /locus_tag="ACL3G6_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HGR0545044.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(11626..11814)
                     /locus_tag="ACL3G6_000463"
     CDS             complement(11626..11814)
                     /locus_tag="ACL3G6_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGR0545045.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(11807..13090)
                     /gene="murA"
                     /locus_tag="ACL3G6_000464"
     CDS             complement(11807..13090)
                     /gene="murA"
                     /locus_tag="ACL3G6_000464"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGR0545046.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(13114..13344)
                     /locus_tag="ACL3G6_000465"
     CDS             complement(13114..13344)
                     /locus_tag="ACL3G6_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HGR0545047.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(13402..14439)
                     /locus_tag="ACL3G6_000466"
     CDS             complement(13402..14439)
                     /locus_tag="ACL3G6_000466"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HGR0545048.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     INDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(14423..14911)
                     /gene="coaD"
                     /locus_tag="ACL3G6_000467"
     CDS             complement(14423..14911)
                     /gene="coaD"
                     /locus_tag="ACL3G6_000467"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HGR0545049.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPIENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(14901..15440)
                     /gene="rsmD"
                     /locus_tag="ACL3G6_000468"
     CDS             complement(14901..15440)
                     /gene="rsmD"
                     /locus_tag="ACL3G6_000468"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HGR0545050.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQITKEIGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYTKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(15505..16497)
                     /gene="asnA"
                     /locus_tag="ACL3G6_000469"
     CDS             complement(15505..16497)
                     /gene="asnA"
                     /locus_tag="ACL3G6_000469"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HGR0545051.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(16608..17291)
                     /locus_tag="ACL3G6_000470"
     CDS             complement(16608..17291)
                     /locus_tag="ACL3G6_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1 family protein"
                     /protein_id="HGR0545052.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(17347..18087)
                     /locus_tag="ACL3G6_000471"
     CDS             complement(17347..18087)
                     /locus_tag="ACL3G6_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HGR0545053.1"
                     /translation="MTIITSKANSVVKNTKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFTLENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQREEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            18121..18399
                     /locus_tag="ACL3G6_000472"
     CDS             18121..18399
                     /locus_tag="ACL3G6_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HGR0545054.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            18477..19403
                     /gene="yidC"
                     /locus_tag="ACL3G6_000473"
     CDS             18477..19403
                     /gene="yidC"
                     /locus_tag="ACL3G6_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGR0545055.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(19478..20272)
                     /gene="pflA"
                     /locus_tag="ACL3G6_000474"
     CDS             complement(19478..20272)
                     /gene="pflA"
                     /locus_tag="ACL3G6_000474"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HGR0545056.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(20398..21648)
                     /locus_tag="ACL3G6_000475"
     CDS             complement(20398..21648)
                     /locus_tag="ACL3G6_000475"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HGR0545057.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(21715..22542)
                     /gene="purR"
                     /locus_tag="ACL3G6_000476"
     CDS             complement(21715..22542)
                     /gene="purR"
                     /locus_tag="ACL3G6_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HGR0545058.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(22809..23750)
                     /locus_tag="ACL3G6_000477"
     CDS             complement(22809..23750)
                     /locus_tag="ACL3G6_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HGR0545059.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(23740..24996)
                     /gene="rmuC"
                     /locus_tag="ACL3G6_000478"
     CDS             complement(23740..24996)
                     /gene="rmuC"
                     /locus_tag="ACL3G6_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HGR0545060.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYEVGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(24998..25660)
                     /locus_tag="ACL3G6_000479"
     CDS             complement(24998..25660)
                     /locus_tag="ACL3G6_000479"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HGR0545061.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLLLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEQNPQAEV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(25623..26279)
                     /gene="rpe"
                     /locus_tag="ACL3G6_000480"
     CDS             complement(25623..26279)
                     /gene="rpe"
                     /locus_tag="ACL3G6_000480"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGR0545062.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(26290..27168)
                     /gene="rsgA"
                     /locus_tag="ACL3G6_000481"
     CDS             complement(26290..27168)
                     /gene="rsgA"
                     /locus_tag="ACL3G6_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HGR0545063.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(27170..28042)
                     /gene="rsmA"
                     /locus_tag="ACL3G6_000482"
     CDS             complement(27170..28042)
                     /gene="rsmA"
                     /locus_tag="ACL3G6_000482"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HGR0545064.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILVDTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(28293..28574)
                     /locus_tag="ACL3G6_000483"
                     /pseudo
     CDS             complement(28293..28574)
                     /locus_tag="ACL3G6_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333255.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(28567..29208)
                     /locus_tag="ACL3G6_000484"
     CDS             complement(28567..29208)
                     /locus_tag="ACL3G6_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0545065.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(29210..31240)
                     /locus_tag="ACL3G6_000485"
     CDS             complement(29210..31240)
                     /locus_tag="ACL3G6_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGR0545066.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(31317..31613)
                     /locus_tag="ACL3G6_000486"
     CDS             complement(31317..31613)
                     /locus_tag="ACL3G6_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGR0545067.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(31933..32832)
                     /locus_tag="ACL3G6_000487"
     CDS             complement(31933..32832)
                     /locus_tag="ACL3G6_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0545068.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(32904..33464)
                     /gene="rnmV"
                     /locus_tag="ACL3G6_000488"
     CDS             complement(32904..33464)
                     /gene="rnmV"
                     /locus_tag="ACL3G6_000488"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HGR0545069.1"
                     /translation="MKERISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(33464..34237)
                     /locus_tag="ACL3G6_000489"
     CDS             complement(33464..34237)
                     /locus_tag="ACL3G6_000489"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HGR0545070.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPMIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIRLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(34542..35435)
                     /locus_tag="ACL3G6_000490"
     CDS             complement(34542..35435)
                     /locus_tag="ACL3G6_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall surface anchor protein"
                     /protein_id="HGR0545071.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEVTPEY
                     KLETTPGGDKGGNIGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRLVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(35719..35853)
                     /gene="rpmH"
                     /locus_tag="ACL3G6_000491"
     CDS             complement(35719..35853)
                     /gene="rpmH"
                     /locus_tag="ACL3G6_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HGR0545072.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(35998..37212)
                     /locus_tag="ACL3G6_000492"
     CDS             complement(35998..37212)
                     /locus_tag="ACL3G6_000492"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR0545073.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(37368..37661)
                     /locus_tag="ACL3G6_000493"
     CDS             complement(37368..37661)
                     /locus_tag="ACL3G6_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545074.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVKVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            37810..38262
                     /locus_tag="ACL3G6_000494"
     CDS             37810..38262
                     /locus_tag="ACL3G6_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGR0545075.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(38297..39685)
                     /locus_tag="ACL3G6_000495"
     CDS             complement(38297..39685)
                     /locus_tag="ACL3G6_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0545076.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELHRQL
                     KAYERHKERNKS"
     gene            39751..40713
                     /locus_tag="ACL3G6_000496"
     CDS             39751..40713
                     /locus_tag="ACL3G6_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HGR0545077.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HTLDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLTMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(40710..40901)
                     /locus_tag="ACL3G6_000497"
     CDS             complement(40710..40901)
                     /locus_tag="ACL3G6_000497"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545078.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHVFEVVDRTDEVS
                     NHTYGKATLTWFAEIFEEY"
     gene            complement(40965..41975)
                     /gene="ccpA"
                     /locus_tag="ACL3G6_000498"
     CDS             complement(40965..41975)
                     /gene="ccpA"
                     /locus_tag="ACL3G6_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HGR0545079.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(42400..42999)
                     /locus_tag="ACL3G6_000499"
     CDS             complement(42400..42999)
                     /locus_tag="ACL3G6_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0545080.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVAVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(43001..44098)
                     /locus_tag="ACL3G6_000500"
     CDS             complement(43001..44098)
                     /locus_tag="ACL3G6_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0545081.1"
                     /translation="MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGLMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMCEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     DSMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(44098..44835)
                     /locus_tag="ACL3G6_000501"
     CDS             complement(44098..44835)
                     /locus_tag="ACL3G6_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0545082.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGDINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(44837..45721)
                     /locus_tag="ACL3G6_000502"
     CDS             complement(44837..45721)
                     /locus_tag="ACL3G6_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0545083.1"
                     /translation="MDMIKVQGLHKNIKGKAILKDISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLSVTSSQLDYIRGYLPQENVIVQKLKVKELVAFFQSIY
                     PNPLSNQEIDQLLQFDKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVQDLKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(45708..45902)
                     /locus_tag="ACL3G6_000503"
     CDS             complement(45708..45902)
                     /locus_tag="ACL3G6_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545084.1"
                     /translation="MKKAFLYLFIGLSLVVWLVEMFTGWFDQALLRQFIRGAWGLGFM
                     IFIAFPMGMEWLKGEYHGHD"
     gene            complement(45899..46090)
                     /locus_tag="ACL3G6_000504"
     CDS             complement(45899..46090)
                     /locus_tag="ACL3G6_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545085.1"
                     /translation="MKNKMIVAMSLVAAGVMTYLMFSGLDEDFYHFPWELFAGFGMMS
                     WLIREGLKLVSDVKKEFEK"
BASE COUNT        13312 a        10796 c         8829 g        13602 t
ORIGIN      
        1 tattccatgt tattttgagg aagatattgt gaaagtcaaa gatgatgata aagttgagtg
       61 gaatttgtta gaatttcaaa aatttagagc atttttgact tagtaatctg tgttgaaggc
      121 tcaaaaccta tggtaaaaaa gtaactttga aaacgtattg cctccaaaga tttagttaaa
      181 taatgattta acacaaaaag aaattattga agttctggaa agatgttgtt tcagtattga
      241 gaaaaggtgg gaaaaacttg cgattttcac agagaaagga agaaaaagta tagaaatata
      301 gtcaattgaa acaagaacag gataaaagaa ccttttgtgc catatttttc tcctttcgct
      361 ttacaattgg attgaacacc tttattgtat cgcgtttgga gtttttttgg tataaccttc
      421 gacgcgcacc cgcatagcgg gtgttttttt gtctcgcacc taacggagcg agacgaacta
      481 atagtcactt aatcaaaaaa cgcaccatat caaaaactaa aaagtttgat atcatgcgtc
      541 atgtcttaaa ctaattgact atactttcta ttcaaatgag cttttaacca attgattgag
      601 ccaatccact cttaaaacca aagagcaatt tctcgcttag ctgactcttc tgaatctgaa
      661 ccatgtacaa cattttggat aacctcattt tctccagcag cttttgcaaa gtcacctcga
      721 atagtgcctg gtaaagcttc ttctggacga gttgcaccca tcatggtccg ccaagtttcg
      781 attactttgg gaccagaaat gacacccaca agaactggac ctgaagtcat gaattcacga
      841 atcggtgggt aaaaactctg accaaccaag tcctgatagt gctggtcaat caactcttct
      901 gaaacctgtg aacgaaactc caatttttcg attgtaaatc cacgttgttc gatgcgcttt
      961 aacacttcac ccactagccc tctttttaca ccatctggtt tgatgataaa gaatgtttgt
     1021 tccatacccg tctcctttgt cagcttcttt cttttatttt accacatttc gtggaaaaat
     1081 ggagaaagtt ttcagaagag agaatgagag aacccgaggg ttctctcatt ctctcttatt
     1141 ctactgtttc ttccacagtt tcaacggcag tatccacaac tacttctgtt gtttcttcat
     1201 ttccttcttc ctctactgga ggattaaggt attcttcttc gttgacagca tgtggttcaa
     1261 ggttacggta acgggccata ccagtaccag ctgggatgat cttaccgatg ataacatttt
     1321 ctttaagtcc aaggagatgg tctttcttac cacggatagc tgcgtcagta aggacacgag
     1381 ttgtttcctg gaaggaagcc gctgacaaga aactgtttgt ttcaagtgag gctttggtaa
     1441 ttcccataag gactgggcga cctgtcgctg gaactccacc tgcgataagg acatctttgt
     1501 tggcatctgt aaagtcattg atatccatga gggtacccat gagaagatct gtatcacctg
     1561 gatccatgac acggacttta cggatcattt gacgaaccat tacctcgatg tgtttgtcac
     1621 cgatttctac cccttggcta cggtaaactt tttgtacttc accgagaagg tacgtttcaa
     1681 ctgacaagac atcacgaact gcaaggagac gttttggttg gatagaacct tctgtcagag
     1741 cagcaccacg cgctacttgg cccccaactt cgacacgcat acgagctgta aatggaacga
     1801 catattcacc ttcgccagtt tcacccttaa caaagacttt cttggtacga gttgatgcat
     1861 cctcttcgat agcagtaact tgtcctttaa cctctgtgat aaccgcttcc cctttaggat
     1921 tgcgggcttc aaagatttct tggacacgag gaagaccctg agtgatatcg gtatttgagg
     1981 caaccccacc tgtgtggaag gtacgcattg taagctgtgt accaggttcc ccgatagatt
     2041 gggcagcgat tgtaccaact gcttcaccaa cttcaaccgc atcaccagtc gccaagttga
     2101 taccgtaaca gtgacggcag acaccgtgac gagtgttaca tgtaaataca gaacggatag
     2161 tcacttcttc cacaccagca ttgacaattt cacgcgcctt gtcttctgta atcaattcat
     2221 ttggaccaat aatcactgca ccagtttctg gatgtttaac agttttctta gtgtaacgac
     2281 cgttgagacg ctcttcgaga gactcgatca tctcttttcc ttctgcgata gaacggatca
     2341 agagaccacg gtcagttcca cagtcgtcct cacggatgat aacgtcttgg gcaacgtcga
     2401 ccaaacgacg agtcaagtaa cctgagtcgg ctgtcttaag ggccgtatcg gtcatacctt
     2461 tacgagcacc gtgagttgag aagaacattt ccaataccga caaaccttcg cggaagtttg
     2521 aaaggattgg caattccatg atacgtccat tcggagcagc catcagacca cgcataccgg
     2581 caagctgtga gaagtttgag atgttaccac gggctccaga gtccatcatc ataacgattg
     2641 ggttcttagg atcttgatta gcaatcaagc gtttctcaag tttttcacgg gcagcacgcc
     2701 attcagctgt aacagcattg taacgctcgt cgtctgtgat cataccacga cggaattgtt
     2761 tggtgatttg ttcgacacgt ttgtgtgatt cttcaatgat ttcagccttg tcatcaacga
     2821 ctgggatatc ggcaataccc actgtcaatc ctgcaagagt tgagtggtgg taaccgaggt
     2881 tcttcatgcg gtcaagtagg gcagaagttt ctgtcgtacg gaaacgtttg aagatttcag
     2941 cgatgatatt tccgaggttt ttcttcttga atggagggtt gagctcaaga ttgctgatag
     3001 cttccttgat atctccacca agtggcaaga agtatttagc tggaacacct tctgtcaagt
     3061 tggcattgtt tggttcttgc aagtatggta gcccctctgg catgatatcg ttgaagagaa
     3121 ttttaccaac tgttgtaagc aagaccttat gtctttgctc ttctgtccaa ggcttgttga
     3181 ggctgtctgt tgcgatacca acacgtgagt ggaggtgaac ataaccattg cggtaagcca
     3241 taaccgcttc gtcacggtct ttgaagacca ttccttcacc ttcgcgacca gcttcttcca
     3301 tggtcaagta gtagttaccc aaaaccatgt cctgagatgg agtaactacc ggtttcccat
     3361 ctttcgggtt caagatgtgc tcagcagcta gcatgaggat acgagcttct gcttgtgctt
     3421 cttctgaaag tggtacgtgg atggccattt ggtccccgtc aaagtcagca ttgtaggctt
     3481 cacagacaag tgggtgcaag cgaagagcct taccatcaat caagactggc tcgaaggctt
     3541 ggatacccaa acggtgaagg gtcggtgcgc ggttcaaaag cactgggtgt tctttaatca
     3601 cttcttcaag gatatcccag atacgctcat ctccgcgttc caccaagcgt ttagctgctt
     3661 tgacgttttg cacgatatca cgggcaacga tttcacgcat gacaaatggt ttaaagagtt
     3721 caatcgccat ttcacgtgga acaccacatt ggtacatctt aagagttgga ccaacggcga
     3781 taacggaacg tcctgagaag tcaacacgtt taccgagcaa gttttgacgg aagcgtccct
     3841 gtttaccttt aagcatgtgg ctcaatgatt tcaatggacg gctacctggt cctgtgattg
     3901 gacgaccacg acgaccattg tcaatcaaag cgtcaactgc ttcttgaagc atacgcttct
     3961 cattttgaac gatgatacct ggtgcattta actcaagcaa acgagccaaa cggttgttac
     4021 ggttgataac acggcggtaa aggtcattca agtcagatga ggcaaaacgg ccaccatcca
     4081 actgcaacat tggacgaaga tctggtggga taaccggaag gatgttaaga atcatccatt
     4141 caggtttgtt tccagacttg taaaaggcat ccaaaacatc caaacgacgg atggctttga
     4201 cacgtttttg tccagtagct gttttcaatt cttctttgag ttcagcaatt tctttttcaa
     4261 gatctacttg cttcaaaagg tcttggatgg cttccgcacc catcttggca acaaatgaac
     4321 cataaccata ttcacgcaag cgctctcggt attcgcgctc tgtcatgata gacttgtgct
     4381 caagtggtgt atccttagga tcaatcacca cataagccgc aaagtagata acttcctcga
     4441 gggcacgagg gctcatatca agggtcaagc ccatacggct tggaatcccc ttgaagtacc
     4501 agatgtgaga tacaggagct ttcaattcga tatgtcccat acgctcacga cgaactttcg
     4561 tacgcgttac ttcaacccca cagcggtcac aaacaattcc tctgtaacga atgcgtttgt
     4621 acttaccaca agcacattcc cagtcttttg taggaccaaa gatcacttca tcaaagagtc
     4681 cttcacgttc tggtttcaag gtccgataat tgattgtttc aggttttttg acttctccat
     4741 aagaccatga acggacttta cttggagaag ctagggtgat ttgcatactt ttaaaacgat
     4801 ttacatcaac cactatttct tccctttcta ttctaagtga actgcttatt cttgttcagc
     4861 agcttcttct gttgcttccg cttttgttgc tttctcagct tcttcagctt caaaggctgc
     4921 tttagcctct tgggctgctt tttcgcgggc tttttcaagg tcatctacgt ggatgacatc
     4981 ttcgtccatt ccttcatcca agtcgcgaag ttccacttct tggtcatctt cgtctaggac
     5041 acgcatgtca agaccaagag attgcaattc tttgacaaga actcggaagg attctggaac
     5101 acctggtttt ggaattggtt tgccttttgt aatagcttca taggctttca aacgtccgtt
     5161 gatatcgtcc gacttgtaag tcaagatttc ttgaaggaca tttgacgcac cgtaggcttc
     5221 aagagcccaa acctccatct caccgaaacg ttgtccacca aactgagctt tacctccgag
     5281 tggttgttgg gtaacagttg agtaaggtcc gactgaacgc gcatgcaatt tatcgtcaac
     5341 catgtggtgg agtttaatca tgtacatgac tccaacagaa acacggttat caaatggttc
     5401 acctgtacgt ccatcgtaaa ggattgtctt ggcatcgcta tccatacctg cttctttaac
     5461 agttgaccaa agatcttcag agcttgctcc atcaaagact ggtgtcgcaa tgtgaatacc
     5521 aagagtacga gctgccatac caaggtgaag ctccataacc tgaccgatat tcatacgtga
     5581 tggcacccca agtgggttca acatgatgtc gactggagtt ccgtctggaa ggtaaggcat
     5641 gtcttctaca ggaacgatac gagagacaac ccctttgttt ccgtgacgtc cggccatttt
     5701 atctccgacc ttaatcttac gtttttgagc gatgtaaaca cgaaccaaca tgttaacacc
     5761 tgattgcaac tcatctccat ttacacgtgt aaagatctta acatcacgaa cgacaccatc
     5821 ggcaccgtgt ggtacacgaa gagaagtatc acgcacttca cgagacttgt ctccaaagat
     5881 agcgtgcaag agacgttctt cagctgaaag atctttctca cccttaggtg ttactttacc
     5941 tacaagaata tcaccttctt taacctcagc accaatacgg ataatcccca tttcgtcaag
     6001 gtctttgagg gcatcttcac caacgtttgg aatttcgcga gtgatttctt caggcccaag
     6061 ctttgtatcg cgcgtttctg attcgtattc ttcaaggtga acagatgtgt agacatcgtc
     6121 cttcaccaag cgttcgctca tgataacggc atcctcgaag ttgtaacctt cccaagtcat
     6181 gtaggcaacg attgggtttt gtccaagcgc catttctcca ttttccatag aaggtccgtc
     6241 agcgatgaaa tcgccttttt caacgacatc accaactttt acgagagtgc gttggttgta
     6301 agcagtacct gagtttgaac gacggaattt ttggatgtgg taaacatcca atgaaccatc
     6361 ttcacgacga acttctacct tgtcagcatc tgcgtaagta actttaccat catactgagc
     6421 aatcacagcc gcaccagaat cgtgggctgc ttggtattcc ataccagtac caacgtaagg
     6481 tgcctgagga ttaatcaatg gcacagcctg acgttgcata ttggctccca tgagggcacg
     6541 gttggagtca tcgttttcca agaaaggaat acatgctgtc gcaacggcaa ctacctgttt
     6601 tggtgaaacg tccatgtagt caacaatatt agctggatac tcttggttga ccccttggtg
     6661 acgtcccatg acaatcttct cagcaaaggt tccatcttca ttcagacgag agttagcctg
     6721 agctacagta tattcatctt cttcatcagc tgtcaaccaa acaatttcgt tcgtgacaac
     6781 acctgtttca cggtcaacct tacggtatgg tgtttgaaca aaaccatatt tgttcaagtg
     6841 tccgtaagat gacaagttat tgatcaaacc gatgttaggt ccttcaggtg tctcgattgg
     6901 acacatacga ccatagtgag tgtagtgcac gtcacgtact tcatatccgg cacggtcacg
     6961 agtcaaacca ccaggtccta aggctgacaa acggcgtttg tgagacaact cagaaagcgg
     7021 gttgtgttgg tccatgaact gtgacaactg tgatgaacca aagaattctt taactgcagc
     7081 tgttacagga cggatattga taatttgttg tggtgtcaag acttcattgt cctgaacaga
     7141 catacgttca cggacattac gttccatacg agaaagtccc aaacgtactt ggttggcaag
     7201 caattcacca accgcacgga tacgacgatt tccaaggtgg tcgatatcat ctacacggcc
     7261 aagtccttca gccaagttga ggaagtagct catctcagca aggatatctg caggagtcac
     7321 cgtacgaacc ttgtcatctg ggttagcatt accaatgatc gttacgacgc gatctggatc
     7381 agttggagca ataaccttga atttttgaag aacaacaggc tcagtcacaa cggctgcatc
     7441 gtttgggatg tagacaatct tgttcaagtc gccatccaaa tggctttcaa tgctttcaat
     7501 cacgctacga gtcataatcg taccagcttc taccaagatt tctccagttt cagggtctac
     7561 caatggctct gcaatggttt ggttgagcaa acgtgtttta acattgagtt ttttattgat
     7621 tttgtaacga ccaactgctg ccaagtcata acgacgtggg tcaaagaagc gagctacaag
     7681 caagctacgt gagctttcag ccgtcttagg ctcacctgga cgaaggcgtt cgtaaatttc
     7741 tttcaaggct tcgtctgtac gagagtccat tggattcttg tggatatctt tttcaacagt
     7801 gttgcgaacc aattcgctgt ctccaaagat atcaaagatt tcatcatcac ctgagaaacc
     7861 aagagcacga accaaggttg taaatggaat cttacgagta cggtcgatac gagtgtaggt
     7921 gatatctttt gagtcgcttt caagttccaa ccaagctcca cggttaggga taacagttga
     7981 accatagccc accttaccat ttttgtctac tttgtcgtta aagtaaacac ctggtgagcg
     8041 gaccaactga gaaacgataa tacgttcacc accattgatg atgaaagtac ccatttctgt
     8101 catgattggg aaatcaccaa agaaaacttc ttgggtcttg atttcgcctg tttctttatt
     8161 gatcaaacgg aaggttacaa aaattggtgc tgagtagcta gcatcgtgga tacgagcttc
     8221 ttctagcgtg tattttggtt ccttgatttc atatccaaca aattccaact ccattgtgtc
     8281 tgtgaagttt gaaattggca atacatcttc aaacacttcc ttaagaccgt ggtctaggaa
     8341 agctttgaat gagtcagttt gaatttcaat caaatttggt aagtcaagaa cttctttgat
     8401 tcttgaaaaa ctacgacggg tacgatgttt cccgtattga acgtcatgtc ctgccaagat
     8461 gattctcctt tgtaaataag ttccaagcct tgtcaatcag gcttttctaa tcgtcatatg
     8521 gttgtaaacc ccttatcacc gtgtcctctt gacgaatttt cagaatcttt aagcctctgt
     8581 tacaaatgct cataatcttg aaaaaaagca caaaaagagc agctaaatct gactttttca
     8641 gaagatttaa ctgctgtgag ccttgtctgg acaatatttc agacaaaacc tacgacaaat
     8701 gattacccat attataccct atttagctag atttttcaag gggtttcagt aggtttttgg
     8761 taaatttttt cccatagaaa acttggcatc acattcgaat cacgctatgg tacaaaaaac
     8821 tgaaaaaact attgactgaa aatcattttc aaggtataat aataaacgtt aaggcggtat
     8881 agccaagtgg taaggcacgg ctctgcaaaa gcttgatcgt cggttcaaat ccgtctaccg
     8941 ccttctataa cttgatttat caggtttcaa atgaacagaa agcccaattt gaagggcttt
     9001 ttttattttc cctcgaataa atacgtataa ctttaaaaac ttttggagcg agtttgtggc
     9061 agagttcttt ccatggcata attccctttt gaaatcaatt gaaaaaagct tcgtcacgcc
     9121 tggtgacaaa agcctctagt ttattctgtt tcttcttcta tttcgacttc tgtgatttgg
     9181 acttttacct tggtaacacg tccattcttc actttatcat tggttaagat aaactgtttg
     9241 ttttggctga ccaattcata gctgagtttc tcagtcgttg gaatggttcc cactcctgtc
     9301 aaataataac cagcgatggt atcaacgtca tcactttcca gctcaacatc aaagtaatta
     9361 ttgaaatcat tgagggtcat agttccttga acaatgtagg tatcctcgcc aatctgatga
     9421 acatctattg ctgctttgtc cgtttcatca tcaatttcac caacaatttc ctctaagagg
     9481 tcttccaaag tcactaaacc agccatacca ccgtattcat ccagcaagat tgccatttgt
     9541 ctttgggtat ttcgcagttc ttttagcaag tcatccacaa aaatagtttc aggtacaaaa
     9601 agtggatctt gtaaaattct cttccaaaca atattgtcaa aaccgtccac aaagcctgcc
     9661 ttaaggagac tcttggtgtg aatgattcca attacattgt ccttatcccc atcataaacc
     9721 gggatacgag aataattttg ttttaaaata ctttggataa tggcttgact atcatcctga
     9781 atatccacca taaaggcatc cgttcgagga accataacct ctcgtgccat cagttcatcg
     9841 agcgaaaaga caccttgtag catctcaatc tcatcagcat ccaatgtttc ttcactattt
     9901 gtcagcatat aggcaatttc atcacgggtc attttttcat ccgcatcatc gaatgacata
     9961 ggagtcaaat ggctcaagaa attggtcgaa gcagctaaaa gccaaacaaa aggactgact
    10021 agttttccga tcccaatgat aaccggcgct gtacgaattg ccaaggcatc ctttagatta
    10081 agagcgattc tcttaggata taattcccca aaaacgatgg aaatataggt caaaaatgcc
    10141 aaggatagaa aagttgccac ggcttgtgct gtttcgccat tcccaagcca agaggcaatc
    10201 acacgtccta gagtatcagt taaactcgcc cctgataaga ttgtaatcag ggtgattcct
    10261 acctgaatgg ttgataaaaa gtggttagga ttttctagta ccttcagcag gcggatgtag
    10321 cgtctgtctc cttcttccgc cttttgttca actcgggcac gattaagaga aaccatggcc
    10381 atttctgtgg ctgagaaaaa ggcatttaat accgtcaaga taaacaataa aacaaattgt
    10441 agcaacaaat tctgactact tgggtcttcc atagttcttc tcctaaaata gtatcttatc
    10501 ctttattata tcacaaaatt taatccaata catattattt ttttcttagc gtaacttcca
    10561 tctctctccc aaaactggaa gttagtctaa gacggatttc cactgatttc acgcgttttt
    10621 ctcatactaa aagctaggtt gtgggaaact ggaagttagt tttagaagtt actatttttt
    10681 cttagtacct attctagccc tgcttaaact agtaaaaaga actcctacat ccataagtga
    10741 cataggagtt taggcttatc ttttactgag ttacagttac ttctccagtt cggtaatcca
    10801 gttgaagtcc cttttgaaca ttgggaacta gaacattgaa ttccaattct ccatccgaag
    10861 acttggcttc aatctgtgaa gctgagggaa ctaaatcctc gtttgaagcg tagtaaaggg
    10921 ttacacggta acggacacgc ttgttttggt ccaaggcttt acgcaccttg ctttcatagt
    10981 agttttgacc agtcgaatac tcggcttgtg cctgatttgc ccaggctgtc tgaacagcaa
    11041 tgtttttagg attgcttgtt gaggcatcaa aaccatccaa accaccgatt aaggcatagc
    11101 ctaacaaatg acctctatcg actgcatggg tataagagcc ctttagattc ttgacctgat
    11161 gccaacctgg aggagtccaa gaagttgaac cattcccagt ttctttacga ttcttgtact
    11221 gacgagtggc cttagacaag agggcattag ctacggttgg aacagtttcc ttgcccactg
    11281 tctttgtttt attgtcagcg tagggcttac ttgaaacctt ggcatctaga tttgttttat
    11341 taccattgac gataaaagca cctgagccat tccactccag actccccttt atttgactct
    11401 tgactgcgtc tgttaagaca ctctctgcca atgcttgact aggagcttca gacgcttgtt
    11461 ttttctgact aagattggtt ttgggactat taggtgccga ctgcatctgc ttgatataat
    11521 agctccctgt agacaaaagc aataacacta gcagtccgat tagtgtctgt cttgtttttt
    11581 tgttcatatt tctccttatc tttagaaaaa ggctggttct ccagcctaat ttcctgtaaa
    11641 tttatgaatc aattcctgcc attttgctgg agacaggata gcccatggat cttgaccctt
    11701 gcccaagatt ccataaccta ccattagacc gattcctaga gccagagtac ctaaaatcag
    11761 tactatgatg actaaaagta aacgattgat tacgtagctt gatttcttat tcatcttcat
    11821 cgcttgcctc aatccgctga atcttagcac ctagctgcgc caacttctca tggaaaccgt
    11881 agtaacctct atccaagtga accaatttac cgaccacagt ttctccctgt gctaccaaac
    11941 ctgtcaaaat caaggctgca ctggcacgaa ggtcagttga aagaacttct gctccctgca
    12001 aaggctgtcc accaacaata cgagctgtat cacggataat ctcagaatgc aagcccatgc
    12061 ggcgcatctc ttctaggtgt tggaaacgat tttcgaaaac tgtctccacc atggttgatt
    12121 cgccttttgc aactgtcatc aaggctgtaa attgagcctg catatctgtt ggaaatcctg
    12181 ggtggggcaa ggttttcaca tgaacagctt ttagattttc tagttgagaa cgaacacgaa
    12241 ttccttcgtc ttcttcaatt acttcaacac ccatttcaag taacttggca atcaagggac
    12301 ggttgtgctc ccagacagcg tctcgaatca agacatcacc accagtcatg gcagcagcta
    12361 ccataaaggt tcctgcttcg atacggtctt ggactacatt gtgagtcgta ccatgaagtt
    12421 tctcaacacc agtaatggtt atagtctctg taccagcacc tttgaccttg gctcccattt
    12481 cattaaggag aatggctaag tcaacaatct caggctcacg cgcagcattc tcaatcactg
    12541 tcaccccatc agccagagtc gctgccatca tcaagttctg cgttgcacca acacttggaa
    12601 agtccatata gatatgagca ccatgcaagc gttctgcctt ggcttcgatg taaccagctg
    12661 tctgactaat cttaaccccc atagcttcca gacctttcaa atgaagatca ataggacggc
    12721 taccaatcgt acaaccacct ggcatggata ccttggcatg acccacacgg gcaaggattg
    12781 gccctaatac aacgatggag gcgcgcatct tgctgacata cttgtaaggg gcttcctcag
    12841 tgatgtcgcc agtagcatcc accttgacaa gatgagcttc ctcatcaaag tcaaccttgg
    12901 cattcaaacc accaactacc tgattcataa taaagacatc cgacaaaatc ggaacattct
    12961 gcaagacggt ctttccttca cttgctagaa tagtcgctgc caacaagggt aagactgcat
    13021 tttttgctcc ctcgatcgtc acgcttccta ccagacgatt atcgccacct tgaaccacaa
    13081 ttttatccat actcgtttcc tttactcttg atttcataat aatcctctaa gcgcttcttg
    13141 ccacaaatga tacaggctaa taaagaaaga actcaggatg tagcctatga caatgctaaa
    13201 aaaggctact aataaacgaa cttttcttgt attctcatct gtcactttta aaaccttctc
    13261 ccatctaaca agatccttta aaaggtaaaa actcacataa ataaagagca tatgactact
    13321 tagagtgaat aataattgaa ccatttgact attataccat cttctctgtt tgtgcgctag
    13381 tttggaaact tcactcaaaa attagggatt gtttttcaag taatcaatcg catcttgtag
    13441 ggttttaacg ggcacgattt tcatatccgt cttgattgtt ttagccgctt ctagggctgt
    13501 ttggtagttg tttttcgcgt ccggatgcgc cttttgttct tcttcgctaa cagggttatc
    13561 aggagcaaag aaaatagcag cacctgccct agccgaagct acaaccttct tatcaatacc
    13621 tccaatgtct cccacattac catcgcggtc aatggtacct gtaccggcaa caatacgacc
    13681 attacgaaga tctgggtgag ctatttgagt atagatagct agactaaaca tgagaccagc
    13741 acttggaccg ccaataccag ctgttgaaaa gctaattggg acattgctga ttacctctgt
    13801 acggtcaatc aagccgattc caattccatt tttgccattt tccaaggtga taatctttcc
    13861 ttctgcagac ttggtttgcc catcctcttc ataggtgacc ttgacggaat cccctaattt
    13921 ttgagaactg acgtaatcaa tcaagtcttt ggaactatca aaggtctgat cattgactgc
    13981 tgtgactgta tcagagatat tgagaatccc tttaaaggtt gaattatccg tcacattcaa
    14041 aacataaact ccaaagtact tgagttcgat atccttacca gctgttttta gtccttgata
    14101 cttggccata ttttgcgatg tttgcatgta gaattgattg attcgcataa attcaacatc
    14161 ggaagaacca cctgtagtct cctgagcact acgaatatct gtaaaaggtg tcaaccaagc
    14221 ataaatcata tgagctaaag tggcatgttg aacaccaacc gtaacgaatt gataggcacc
    14281 agcttcctta tcttctgtgt catttatttt aaggacttgg cgaatatctt ccgaaccacc
    14341 tggaacctct atataataag gcaagggcac tacaaatgcc aagaaagtca caatcaaggc
    14401 cgcaatgacg tataagggcc atctaatctt ttttttcatt tcttatttcc tccaaaatac
    14461 tctcgggaac atagcaggca atatcctgac caaacttcaa aagctctcta acgcctgatg
    14521 aactgatata gagatgttca ggtcgactat gtaaataaat agtctctata tcagaagaca
    14581 gctgatgatt gtagtaatca aaactggctt catattgcaa atccgacgca ttcctcaaac
    14641 cacgcactag acaagtagca cccaatcttt ttgcaacatc gaccaccaat tcatcatgag
    14701 aagccacgac ttcaacattt tccagatgtc ccaaagcctt ttctagcccc cgtttacgat
    14761 tttcgatagg aagaaatcct tgtttgtggg gattaaaaaa aataccgaca tagagcttat
    14821 caaagagtct gctcgcccgt tcaatgatat ccagatgccc atttgtcatc ggatcaaatg
    14881 agcctgtgaa taagccaatc ttatctgaca tagactgtca ccttactaat tccataaatc
    14941 ttttccttcc agatacccag acaggcaatt tcttctggaa gttcaacggc cttatccgtc
    15001 tcgcacacaa ccataacatc ttcagaaaaa agctctctct cagccatttt ttcaatatct
    15061 gctacgattt gttccttggt atagggaggg tctaagaaaa cgaggtcaaa ttccccagat
    15121 acctgttcca atgccctttc tgcatccatc ttgaggagtt gaaattttcc aatttccttg
    15181 gttatctgga tattttcagc cacgatggtc tgagccttac ggtctcgctc caccaaaaca
    15241 gcactggaca tgccacgcga tactgcttcg atagataaac caccactacc tgcataaagg
    15301 tccaagactc gtcccccttc aaagtaggga ccaatcatgt taaaaatggc tcccctaacc
    15361 ttatccgaag taggtcttgt cgtcttgcct tctagtgtct tgaggggacg tcccccatag
    15421 attcctgata cgattttcat actgtttatt ataccaaatt atagacaaaa agagaaagaa
    15481 aaccgaacct tgcggttcga ttctctacaa aatattttcg taagtatcgc ggacttcttg
    15541 aggccaaaca cttgtttgca cttctccgat gtgtctcttg cgaagtagga acatggccat
    15601 acgagattgt ccaattcctc caccgattgt caatgggaat agaccattca acaaagactt
    15661 gtgccattcc aattccaagc ggtcttcatc acctgtaatt tccacctgac gtctaagagt
    15721 ttcttcatct acacgaattc ccatagaaga caactcaaag gctccaccta aagactcatt
    15781 ccagacaaga atatcaccat ttagaccctt gtagccattc tcagactcgc ttgtccagtc
    15841 atcatagtct ggtgcacgtc catcgtgcgg tttaccatct ggcaactcgc caccgatacc
    15901 aatcaaaaag acggctccaa attctttaca aatcgcattt tcacgttctt tcggtgtcaa
    15961 gtctgggtag cgttctacca attcttctgt atggataaag gtgatttgtt ttggcaagat
    16021 agactcgatg tcatagcggg cttcaacagc tagctcagtc aggcgaatag ccttataaat
    16081 cttctcaact gtttctttta gataaacgat gttacgctta ccatttggga taaccttctc
    16141 ccagtcccac tggtcaacat aaacagagtg ggttgcatcc aaggaatcct catctggacg
    16201 aagggctttc atgtggacaa agagaccctc tccttcacca aagccaaaac gagccaaggt
    16261 gtggcgtttc catttagcaa gtgagtgcac cacttcataa gtagcatcag ggatttggag
    16321 aaccttgacc gatactggat tttccacacc agacaggttg tcctgcattc cgtcaccgac
    16381 cttactcaag ataggacctt gaacttcgac aacttctagc ttatctttca aatactgggt
    16441 aaaagtgttt ttgacaaagg aaatttcttc ttgttgatgg ataaaacttt tcttcataga
    16501 caactcctca aaaatttaat aaacgtatta tacacctatt tccaagaaaa gaaaagagaa
    16561 aatttaaaaa aatcagtgtc actcaaaaca ctgatttcat agacctttta gtcattgcga
    16621 ccaaagatac gtagaatact taggaaaaga ttgataaaat caagatagat gctgagagcc
    16681 attgacacca cccaacctgt cgctacacga ccttgtgatt gttcataggc gaggcgaatc
    16741 ttttggttat cccaagcaat caaccctgaa aaaaccaaaa ccatggctac gctaatcata
    16801 taatcaaaga agccactagc caagaaaata ttgactacca tagcaatcag taaaccaatg
    16861 agagctgcca tcattgctcg accaatccca ctcaagtctt tcttggtaaa gataccaact
    16921 gccgccatga caaagaagag aagggcgctc gatacaaagg cagataaaac tgtacccgga
    16981 gtatagaaag ccaccacaaa actaagggta aagccgttta aaacggagta aagtaaaaat
    17041 actggaagag cagctggact atttcttgaa gccatgctac tggcaacgaa aaccaaagcc
    17101 aactccgcaa aagtagcaat ggtcaaccag agacgcccct gcatcaaaaa gtaaaccaac
    17161 tgagactgaa agaccgtcaa cataaggcct gataccaaag cagatagtcc gattcccaga
    17221 ccaacaaagg cataaacctt agcgtaaaat tgattgagac ctgcacggtc atgtataata
    17281 gtgtgattca tccatttctc cttttctgtg aacatctttc cttgattata acaaaaaaag
    17341 ttaaaattag cttaaatgga agattaaaat accggctgca accgcaacat tcaaactctc
    17401 ggcctgcccc ttcatgctaa tatggaccaa ctggtctgca ctttcagcca taaggggact
    17461 aattccttga ccctcatttc ccataactag tacaaaattt tctatagaag gcagttctct
    17521 gtaatcaaca gaatctttag atagggttgt tgctagcact gggatagcta cctttttagt
    17581 ttcgtcaaga agcgcttgac tagtcatccg gtaaatgggc agatggaaat gactaccttg
    17641 catggaacgt agggttttga gactgtagat gtctgccgac ttatctgaaa caatcactcc
    17701 tgtaaaacct gctgcatccg cagttcgaat gatagttcct acattaccag gatcttgcac
    17761 atcttccaaa aacaagaact tgccctgact caaatcagct tgtcctactt cttctctttg
    17821 aaccacggca acaattccct gtggagtctg agaatccgcc aaatctagca aaatatcctc
    17881 tgacacccag acagtttgcg aaaaagtagc taactgatct cgataatttt ctagggtaaa
    17941 gattttctca atcgtcactc cagcttgaac agcttcttca aacaagtgcc agccttcaat
    18001 caaataggct gacttgcggt attttttttg gtgtaatttc ttggtatttt ttaccacaga
    18061 attggctttt gaggttataa tagtcataga aatattataa cacaatcaaa ggggtttggt
    18121 atgcaaaagg ttagaatgat tgcccaaggt agggtacagg gagtcggctt tcgttggggt
    18181 gtttacagct tggcccttga aatcggtggc atcacaggtc gggtatggaa taacgacgat
    18241 ggcacagtgg aaatcttagc ccaagcagac tcatctgcta tcatggcaaa atttatccaa
    18301 gaaatccgaa aaggaccgac acctttttca aaagtaagct acttagatgt caaactaagc
    18361 aactttcctc cctactctga ctttaaaatc gcaaattagg tctccagaac tattgtatat
    18421 tttgtaaaaa aacagtagaa tagaaaggta taatttttaa agaaggaata aaaacagtga
    18481 aatctattaa acgttttgca ttctcggcta tgggagtggc tatgttgctt gtcttgactg
    18541 gctgtgtcaa tgtcgataaa accacaggtc agccaacagg atttatttgg aatacgatcg
    18601 gagcgcctat ggctgaagcc atcaagtact tcgctactga taaaggtcta ggctttggtg
    18661 tcgctatcat tatcgtaacc attatcgtac gcttgattat cttaccactt ggtatctacc
    18721 aatcatggaa ggcaacgctt cactctgaaa agatgaacgc tctcaagcat gtccttgagc
    18781 cacaccaaac acgtctcaaa gaagcaacta ctcaagaaga aaaactcgaa gcccaacaag
    18841 ccctctttgc cgctcaaaaa gagcacggca tcagcatgtt tggtggtgta ggatgtttcc
    18901 ctatcctcct tcaaatgcct ttcttctctg ctatctactt tgctgcccaa catactgaag
    18961 gggttgctca agcaagctac ctaggcattc ctctaggttc tccaagtatg attttggttg
    19021 cctgtgctgg tgtcctttac tatcttcaat cgctcctttc acttcacggg gtagaagatg
    19081 aaatgcaaag agaacaaatc aagaaaatga tttacatgag cccactcatg atcgtcgtct
    19141 tctccctctt ctcaccagcc agtgttacac tttactgggt tgtcggtggt ttcatgatga
    19201 ttctccaaca gtttatcgtc aactatatcg ttcgtccaaa acttcgcaaa aaagtccgtg
    19261 aagaactagc caagaaccca ccaaaagcaa gtgctttctc taaaccaagt ggacgaaaag
    19321 acgttacccc tgaacaacca actgctatca caagcaagaa aaaacacaaa aatcgcaacg
    19381 ctggaaaaca acgttcgaga taagaagaaa aaggcttagc tgatttgcta agtctttttg
    19441 caaatcaaaa gcccgatgtt tccatcaggc ttcttttcta tccatgtaca cgtttcatat
    19501 aatcttgata actttcggta tccatgagtt ttttagcgtt cttgacgcga tctgctgttg
    19561 gtggtttgac tccttcgagg gaatatggaa ttccaagttc acgccacttg aactcaccca
    19621 tggtgtgata aggtagaatt tcaaacttat caacattttt gagggtcttg acgaacttac
    19681 caagttcaat caagtcatca tctctgtctg tcaatcctgg aactagcacg tggcgaatcc
    19741 agacaggttt tccaatatct gatagatact gggcacaagc caagatattt ttattagttt
    19801 gtctagtgac aatcttgtgc tgttcttcgt tgatttcctt gatatccaaa agaaccaagt
    19861 cagtgacagc catgagtttg tcaaacttct caaggtaacg tggtttatta cggaaaggaa
    19921 gagcacaggt atccaaggta cagtggattc cttgttcctt agccttggtg aagagagcaa
    19981 tcaggaaatc aatctgcaag agagcttctc ctccactgac tgtaatccca cccttatttc
    20041 cccagaaacc acggtagcgc aaggcctctg tcaagacatc atctaccgtc cgttcacgtg
    20101 acttattgga ctccatagcc caagtgtctg ggttgtggca atactggcaa cgcatgtgac
    20161 agccctgcaa aaagacaata aagcgaatac caggcccatc tactgaccca aagctttctg
    20221 tcgaatgcac cattcctgtc acttgtccat aatcaattgt ttcttcagac atatcgttac
    20281 cttccttgaa aacgttttat agttttatta tatcatgact tgaaggaaaa acaagatttt
    20341 tgcctatttt ttagaaagca atctgttttt caatttcatt ttcaatctat tatcagatta
    20401 ttcttcaaaa tcgaagccat ataaggttgc aaaatagtcc tcagggcgct ctgcacggcg
    20461 gatttgacgg gctttacctt cttcggtata gaggatttcc gcagaacgta atttggcatt
    20521 atactggtag cccattgaaa atccgtgggc acctgtatca tgaatgacca gcaaatcacc
    20581 gatttctgta tgaggcagtt cgcgattgac tgcaaattta tcattgtttt cacagagtga
    20641 accaaccaca tctaccgctt cagctggtcc atctggatgg gtcacgttgc taatatgatg
    20701 gtaagctccg tacatagctg gacgcatgag gttgactgct gaggcatcca cacctagata
    20761 ggtacggtag gtttccttct tatgagtcac tcttgtgact agagcaccgt gaggtgccag
    20821 cataaaacga cccaattcgg tgaaaatctt gacctgacca agacctgctg acgtaagaac
    20881 ttcttcatac accttacgaa ctccctcacc aatcaaggcg atatcgttcg gctcctggtc
    20941 tggacgataa ttaacaccaa taccgccaga aagattgata aagtctagcg aaatgcccaa
    21001 cttttccttg atttcaacag ccagttcaaa gagctgacga gccaactctg gataatagag
    21061 atgggtcacg gtattggacg ctaggaagga gtgaatccca aaagtcttgg ctcctttttc
    21121 cttcaagata gcaaaggctt caaagagctg gtccttggtc atgccaaact tagcctcccc
    21181 aggattgtcc ataatgtctg tccccagttc aaaaacgcct ccaggattat aacgacaaga
    21241 gatgatttct ggaatgcctg ctactctctc cagatgttca atatcttcaa aggcatccaa
    21301 gttaatggtc gcacccaatt cacgtgcata ggcgtattcc ttgtctggcg tgttgttgga
    21361 agagaacata atctcagaac ccagaaagtc cagtttatgg ctcatcaaaa gctctacata
    21421 actagagcag tccacaccac aaccttcttc ttggagaatt ttcaaaatag ctggagttgg
    21481 agtagcctta actgcaaaat attccttaaa gcccttgttc cacgaaaaag cttggttgac
    21541 ggctcttgcc ttctcacgaa tccccttctc atcatacaag tgaaagggag tcgggaactc
    21601 ggcaacaatc gcttctaact cttctctatt gataaatggt gttttcataa gcttccttct
    21661 attctgtttg caaagaaagg ctgggacaat cgttccaacc tttagttcta tctcttattt
    21721 atcttcgtca aagatattgc caacctcaac atcgatggct tggttcttga catcaatatt
    21781 agttaccttc aagagtgact tgtagtcaaa ctgcttttca cgttcttctt gggcattgtc
    21841 cgcaaagacc gctacacctg ccagttctga gtcgaactcg cgcaagagac taatcatacc
    21901 gttgaccgtt ccgccacctt tcaagaagtc atccacaatc aagacacggc tgcctgcctt
    21961 aagactacgt tttgaaagga acattttctc gatacggtca ccacttgaac ctgaaacata
    22021 gttgacgcta acagttgaac cttcggtaat tttcaggtca cggcgcacaa tgacaaaaga
    22081 gacattgagg acattggcaa ctgcatttgc aagtggcaca cccttagttg ctacggtcat
    22141 aaccgcgtca attttttggt ccataaagct tttggcaata atacgaccaa tatttttcaa
    22201 gatggctggt gtgctaagca aatcagacag atagatataa ccacctggca agatacggtc
    22261 actttctgac aacttggtac gcaagtcttc aaccatttcc ttagcatcct gactcgaaat
    22321 agacggtgtg aagatgacac ctccgccagc cccagtcact gtctggatat gaccgatttc
    22381 aatttcctca aaggcgcgtt tgataatgac gatatcttct gagatggatg atttagcaga
    22441 ctcatacttt tcagcaaaag tattgagact agttagttta taaggattat taatcaaata
    22501 gttggaaatg acaaccatcc gatcacttct tcttaatttc atttctattt cctattccat
    22561 ttttattcaa aaaatcaaaa agcaaactag aaagctggtc gctggtggtt caaaacactg
    22621 ttttgagatt gtcgatagaa ctgacaaacc ctgtaatata cctgcatata tacatacgac
    22681 aaagcgatac taccctagtt tgaagatatt ttcgaagagt attcattttt gtcttttact
    22741 tattatacca tattcacata aaaaaacgaa cattcttatc ctaaaaaatg ctcatttttc
    22801 ttaaattatc aatctaaatc tggtttatag aaggaacgat tatccatagc gaagatttta
    22861 ttggtcatct ctcctttatc caccaaagcc agagctgttg acatcatcat catgcttgca
    22921 tccagattgt caatcatatg gataatctct gcctccataa tacgtggacg gactggactt
    22981 ccatattcaa gcaagccgtg gtgactgagg atgacatgac gaagcaaaac gacttcttcc
    23041 ttggtatcat cgatgccgag ttccataact gtcttggtaa tttcgctatc aatgagagcg
    23101 atatgtccaa gaagattacc tcgcactgtg tactctgtct ggtctggccc cgtcaactcg
    23161 atgaccttag ccaagtcgtg caacataatc cccgcataga gcagactctt attgagctga
    23221 ggataaactt cgctaatagc gtctgccaaa cgtaccatgg tcgccgtatg ataagccaac
    23281 cccgtttcaa aggcatggtg gttggtcttg gcagctggat aggagtagaa ttccttatca
    23341 tacttggtgt agagatttcg gacaatccgt tgccagacag gattttcaat tttgaaaatc
    23401 atttgcgaca tgtagtcacg aatttccttg acatcaactg gtgacttgac cttgaaatcg
    23461 gctgggtcat tgggttcacc agcttgaggc aggcggagag taatttgatt gacttgaggg
    23521 gtattgttat aaacttctcg gcgtcctttc atgtggacaa ccttacctgc ggtaaaggcc
    23581 tcaatgttat gaggttgggc atcccagagc ttcccatcaa tctcgccact atcatcttgg
    23641 aaggtaaagg ctaggtagtt tttcccagct cgagtttgcc tcaggtcagc tgatttgatt
    23701 aggtaaaagc cttcaaatag ctcatctttt ttcatgtgac taatcttcat attcttcctc
    23761 attttcttga aaatggagta gatcaagcgc aggctcgcct tctgacaact caatgtgacg
    23821 gagcgtccgc tcgatagcta tggtacgacg gtttaataat tcatcaatat tgccagaggc
    23881 atgttggaga tgtttttgtg ccttgaccag aataccacca aacttgccaa actcggtctt
    23941 gacactggca agagtcttgc tgatatggtc ggcactcttt tggatattaa gggtcttgaa
    24001 accaactgat agggagttaa gaagggctga tagggtactt ggtcctgcaa caataatctg
    24061 ttcttcccgt ctcaaatcat caaagaagac cggattgcgg acgatttctg agtagagacc
    24121 ttctgtcgga acaaacaaaa ctccaaaatt ggtcgtccga ggtggtgcta tgtacttgtt
    24181 cctaatatcc ctagcaaaac gcttgacact tgctaggagt gacttacgac agcgttcgat
    24241 ttcatccttg tcacctactt cataggcttc ttctaagcgg taataatctg ccagtggaaa
    24301 cttagagtca attggtaggt agacgtattc ttggtcgcct tgtccgggta acttgatggc
    24361 atactccact cgttcactag agttttcaac cgttgcgtat tctcgttcgt actgggcagg
    24421 tgtcatgatg tcttcaataa tttgccccag ttgcaattct cccagaatcc ctcgcgtctt
    24481 ggttccagag agaaccttgt taagagctcc gacatcacgg gcaactgtct gcatttctcc
    24541 aagaccacga ttgacagact ccagttgttt agaaactgtc tcaaaggaag cctgtaagcg
    24601 tgtctgcaag gtcttttcta gtttttcctc gaccgtctgg cgcatttgtt ccaaacgttg
    24661 ctcatttgat tcctgcaagg cttggagacg ttggtctgtc ttgtctctag tttggaggag
    24721 attatctgtc atttcttgac ggacttgggt caggccttgg tgcaattcaa tccgcacttc
    24781 ttgcaaacgg tcgctgacag ccacttccaa atctttttgg tctaactggc tggcttgtct
    24841 ggcttggtca aagcggtaat ccaactggtc tgacaaatga tctgcctgat cctccaagct
    24901 cttacttaag tgtttctcct gcctatcctg tctttgccaa atcagaaaga gaccagctag
    24961 gttggcaatt aataatagaa taagtaaact ttccatccta cctcctgtcc ttgctatgca
    25021 gtacgaccac ataaccatct gggcaagtca ccgacacttc cctatctata tattcgttag
    25081 aagcgtacac ttttttaaag aaaaaattct cctctgtcaa ctcatactta gctccaagaa
    25141 tagtcagctg gctatcccga actggcataa aggctagata gtcgtagtct gaacgaggtt
    25201 ctagctgact ggtcccttct gaacaatagg caatcaaatt ttgcccatcc tcaatttcta
    25261 tttgacgcat atagggtgcc aacttaggat tgctaggtag aaagacattg gccaacatat
    25321 ggtcaatacg gccacccaag gcaccgaaaa tagtgacctc agcctgagga ttttgttcaa
    25381 agatggttaa gagagccaat tccagatctg tatcatcctt ttctggtcgg gcttggacaa
    25441 aatgctgggc acgtttttga atcacctgtc gctcttcttc cgtcacagaa tcaaaatccc
    25501 caactgctag agcaagaagc aagtcttctt ccaagaccca gagcgagcct cgatccaccc
    25561 caacaaaagc atcaaaatct gtccgataat gaccgcggtc tccgcctgca aaaacggcaa
    25621 ccctagtcca gttgttttct gagagtttgt actcgctcat tgacatctcc cttaaagaca
    25681 taggaacctg ctacaaaaac ggtcgcacca gcttctttag cttgggcaat agtttggtca
    25741 tcaatcccac catccacttc gatttcaaag ttcaaacctt tttcctcacg aagagcaacc
    25801 aactcacgaa ccttatccat ggtttctggc agaaaggctt gcccaccaaa acctggatta
    25861 accgtcatga ctaaaacttg gtcaactaga tgaaggacgt gcttgatggc ttcaactgat
    25921 gtgccaggat tgataacgac tgaaggctta actccgagtg aacgaatttt ttggagggcg
    25981 ccatgaatat gaggcgttgc ttctacatgg atactgatga tgtctgcacc tgcacgcgca
    26041 aaatcttcca gatgatgctc agggtttgac accatcaagt ggcaatcgaa aaccatctta
    26101 ctatgaggac gaaggctctc gaccacacct gcaccaaaac tgatttgcgg tacaaaatga
    26161 ctgtccatga tatcgatatg ggcatattct gccccagttg cttctagacg tttgatttca
    26221 cgttcaaagt tggcataatc tgctgccaga attgacggag caatcttgta ttgagacata
    26281 ggtttctcct tattttggaa tttttttgct gactttttta taggtttctc tacgattttc
    26341 aatttcacta aggaattgca ggtaattgtc aaaacggaag gttgcaataa caccctcttc
    26401 aacagctggt ttgacggcac aagacggctc atgggtatgg gtacaagtac ggaacttaca
    26461 atctcggcta acagtagcaa tctctgggaa agcctgattg aggtcttcag cccttgatac
    26521 ttcatagtcc aaggatgaaa atcctggtgt atctgcgatt ttacccccgt tgagattgta
    26581 aaaactaaca gctcgagtgg tatggcgacc gcgacctaga ctgtctgaaa tttctcccgt
    26641 ttcaagattg aggtctggtg cgattttatt gagaagagtt gacttcccaa cacctgtctg
    26701 ccccataaag accgtaacct tgcctgttaa caaagacagg agttcctctt tactggtcac
    26761 aaagtcatag ccgatgtcac cataggtctg ctggtaaaaa tccagttctc ccctatcttc
    26821 caacaaatcc attttggaaa tatagacaat gggatggatg cccttgtgct ccaaaagaac
    26881 caagaaacga tccagcaaat tgctgttaaa atcaggttcc ttgacggaca tgattactac
    26941 agcttgatcg atattgacaa taggcggacg aaccagactg tttttccgtt cgtgaatttt
    27001 gaggatatag ccttctgaat tttcctcggc agagaaatct acccagtccc caacataagg
    27061 ggtatggcct tttttacgga aattcccacg cgcgcgtgtt tgataaacct ggccatcact
    27121 ctccacatag tagaaacctg ccaaggcttt aatgatttgt ccctgcatct tagagtcctt
    27181 gccctttaag tgcgtctgct agaccggcaa attctgccaa gctgagagct tccccacgca
    27241 cacttggtga caagcctgcc tggtccaaag ccttggtcag cttgtccttg acctcttcag
    27301 tcttaccaaa gtaacctgtc aagttattcc acaaggtctt gcggcgatgg gtaaaactag
    27361 ccttggaaac cttaaagaaa aagttctcat cttctactgc tacggctggc tctggacgac
    27421 gcaccatttt caagatggct gaatccacat ttggcgctgg cacaaagacc gtacgaggca
    27481 cgataaaggc aaccttggct gtcatgtaat actgcacggc gatagacaag ctaccgtaag
    27541 ccttggtgtt aggctgggct gaaatgcggt ccgctacttc tttctgcatc atgaccacaa
    27601 actcactaaa aggaatgcca ctctcaatca agtgcatgag aataggcgtc gtgatgtagt
    27661 aaggcaaatt agccactacc ttgattggca ggttaggatt tttaaaattt tggatatgtt
    27721 gcgccaaatc aaccttgaga atatcttcgt taactacagt cacattatca aaatcacgca
    27781 gggtatctac caaaattggc accaaacggt ggtcaatctc aaaagccatg acttgggctg
    27841 cacgctcagc cagaaactcc gtcaaggcac caatacctgg cccgatttcg atgacattga
    27901 cctggtcatc aatttcagcc gtatccacaa ttttttgaag gatattggta tccgtcagga
    27961 aattttgccc gaaggacttt ttaaaggtaa aaccgtgacg ctccagcact gccttggtca
    28021 cgctataatc tgcaattctc atctattctc ttttctatta tctgttacta ctattgtaac
    28081 acattcccct tgtattttgg gaatgaaaat cataccaaaa aactatcttt cctcatgaag
    28141 aaagatagtc ttggaaatct ttaaaagtgg ccttaacagt tctctcgaaa catgcgttca
    28201 tactcttcga aaatctcttc aaaccacgtc agcttcacct tgtcgtactc aagtacagcc
    28261 tgcggctagc ttcctagttt gctctttgat tttcattgag tatcaaaaaa atcagcttct
    28321 tgataacttc tattttcggg tagggtcaaa tccacatcct cctccacatc atccactgtc
    28381 agttcaaccg tttgaggtaa atttttcaaa cgataatgct tttgccttta cccttcaata
    28441 ctagcaaaat caagcaaata gccatgcact aggatttgaa ccaaaaggag atgattggtc
    28501 atatttttat cttctaaacc acctctggca ctaggataat cagataccct gcgaatacgg
    28561 attttttcac acatgagcaa gtttcctcat atcaatgatt tcatcagcct tattccagac
    28621 taggggatta tgggtcgcaa tgatgataat tcgattttca tctttcaaat ccaccaagag
    28681 attcataacc tcctctgaat tttcaggatc aagagctgct gttggttcat ctgccaaaat
    28741 caagggtgga tttttcaaaa tagtttttgc aagggcaact cgttgggcct ctcccccaga
    28801 taaagtatag attttttgtt ctaaatccaa ataccctaga ttaacttttt ctaaagcccc
    28861 cacttgcctt tccaaacgtt ctacttttga gattttctga ccaacaaaac ccaaatccaa
    28921 attttctttg attgattggt tttctaagag gccgaaattt tgaaagagat agcccatctg
    28981 gtctcgaaaa tactcacgag taggaatggt ttttaaatct ttcccctgat agagaaccct
    29041 tccaccatct atcttttcta gctttcccaa gatattcagc agcgtcgtct ttccgcttcc
    29101 actctttccg attaaggcat aaaccttgcc cttctccagc ttgagattca aaccagagaa
    29161 aatcgcgcgg tcattaaatt tcttttccaa tccttgaata tcaatcatct tattttcctt
    29221 tcaatactgc catgctacca gcttcttctt ttttgtcctg ccttactaaa atcaagaggg
    29281 cgttaagcgt aaacaaagct acaactagag cgctaatcaa accatctctt gtcaaaatac
    29341 tagataggac taggccaagc aagagaactc ctccttgcgc cagtaaatac ttgccatgaa
    29401 gttcatagat tgtcatacca gcaagacgtt taatcataag ctcccgtctg aactgctcaa
    29461 aatagagaag attcatggaa tcaaataaca agatagccgt agacagggtc aaaatcgtcc
    29521 caataaggag agagtaaaac tccacccgtt tgtcatttag taccttggca aaaaatagct
    29581 ggctttttac caagtaagaa accttgtgat acagaccttg ctcttttaga gctgtgatgc
    29641 tgtctccata tcgatctagt ttcaaggcac tattagccgt agttccccac aacatccctg
    29701 caacaggtct tgttccagtc gcttgcggcg ttagaactac aataatcgga tcttttaggt
    29761 actggcgtgt tgtcttgtac ccatcattat agaggaaacg ttcctgtcct gtttctgtaa
    29821 aagctagcct tacctgtggg aggtagtgtt tctgactcgt cacttctaca ctttcagatg
    29881 aaaagttttg caggtaatct gtaaacaatc cttggtagta gacagactgc tctcgcaagc
    29941 tctcaggcaa gatcagccca aactctccct cagacaagtt ttgcatcttg tccataaact
    30001 ctgaagaaac ggtaatcttt tcttctatca gatagcgtgg tgagacatag ataacattcc
    30061 ctgacggtgt gtagtcactg agacgattgc catctaggtc cacttctgct ccatctgaga
    30121 aattgtcaac attgctcata atataaaaag agtctgtatt ggctaaccgt tcttcagtaa
    30181 atgtctgcca ctcacgatta tccttacgcg ttccttcttc atcggcaaat gcactagacc
    30241 aaccaaagga tagacggtaa cggtctgagg actggctcca tttattgcta gctctctcca
    30301 tttcctgcat ttcacggtag tggggtagga gagctgtcgc actcgatccg accaccaata
    30361 cagctaagag ttgccccacc atcatcaatg tcatcatacg tttgagaggg agtttccctt
    30421 tcaatagatc caccagacta ttttcctgta aaccaagtag atagacgaca cttagtaagg
    30481 tagaaatccc tgccaaggtc aatccataaa gtagaagagc aatgatgacc agttgcaccg
    30541 ttgccataaa caaggcacct tgataccaga gaatccccaa tcccaaaaga ctggatacca
    30601 gcactgagca gataagctgt ctcacatctt ctaacactgg tctgagagca actccaaaca
    30661 agctctcacc agctattaag cgaatccctg cctgacgaag ggatttgatc cgataaatca
    30721 gggtcagact cataaaggtc agcagaaaaa tagctaaact cagtagcacc ataggggtgg
    30781 ccgtcaatag taagactatc gaaaatggat cttctccatt cgaaacaaag ccttgataac
    30841 caagctcttt caaggtggtc tgtaagctca ctccatccaa acttcctgac acaatcaagt
    30901 aagaccctaa taaatcactc gtttctgcac tctccttgga ggaaatggtc agaccttctg
    30961 gaagctttcc ctcaccataa gtggcatagg taaagcgtgt ttctccagct tcatttggct
    31021 caacgattcg acgagcaatg agactattgt gctctaccgc caagtgactc aaagcctctg
    31081 tcacctcttc ccgactagct actggttgat ttatcatcat tcctgtcaca tcaacagaag
    31141 gatagttacc aaataaaatc tcttctcgat ggtcaacgga agttatcacc atataaagcg
    31201 ataccaatac cattgaaatc aaaataaata aacgtttcat catttcctcc aaaaagttac
    31261 ttggtcactt agtgagaagg tgaccaagta aagctaaaca atagggctat accattctaa
    31321 acattatagt agaatgcaac tttctctccc caagaagtac gaatccatgc acgagaagtc
    31381 cctccagcac cagcatatcc cttgtcagat gaaccagttt ttctgctaac aactgttgaa
    31441 ctatggtatt ttgaagggtg atagtagttt gagtaagcac caccgttacc tgaaccataa
    31501 gtccaaacac caccttctgg gtattgaacg gctgcagagg caactgctac acttccacct
    31561 aatgttgctg caatgctcgc tacaagagct aattttttaa ctgtttgttt catattgata
    31621 ctcctctatt tttgattaca agattgttga gttacttgct cctctttcca ttatcaacgt
    31681 tgatactatt atattaccaa atgatattct aaaattattt gtttttctct aaattgtcaa
    31741 aatagcaccc tgaaatgaac ttttatagtc attatactcc atctttatca cactatcaag
    31801 gacatcaatg tccttaaaat ctaactattt catattattt ttagcttata tctaaaaaaa
    31861 cagttctaaa gacgaacttt agaactgttt tgatacgagg acaaggacat ttttgtcact
    31921 gattcactat gtttataaat attttttgac atcctcttgc cattcctctg tcaatttctt
    31981 tactagaaat ccatctccaa ttagcttcgc aaatgtttta gaagactgat aaaatgattc
    32041 agctaaacta aaatctcttt ctactcttaa tgcttgcttc cacaaaaaca taaatacaag
    32101 aggtttcttt tgataatctt gagttttatc cataatttct tgtaaacacg atagataatc
    32161 attaaaacaa tcagttactc ctaccttttc aagacaacac attcctgaaa taagagtatc
    32221 tctaattata aagtaattct ctatttgagt taccttcttc tgttccaaaa gaaagagcat
    32281 tagcttttcg atttgattta taaatttggc aagatctttt ctaatgagca tttgataaaa
    32341 aaacaaacga atcaacaaca tatcatttat tgaataagct tctttttcta taatctgagg
    32401 catatgttcc tcaagtatta actctgcata ttcaggcctt ctagttctag aagtatccaa
    32461 acacgcctgc aatacttcac atgctaattg ttcttcttta ggaagattat caaagtatgt
    32521 tttataaatc tcttccaaac acgcttcctt cttatcgtac tcctcttctt taccatagat
    32581 tggttcacgt aaaatctggt atttcaattc taaataagca gaaggaagag ctgaaaaatc
    32641 cggcataagg ctataaactg gaactcctag ccggcgagca atataggcta acttgggcaa
    32701 actcggttgc gaagctccac tttcaattcg cgacagttga cgaactgtca gttcttgctc
    32761 atctccacaa aaatctggac gactaattcc tttttctatc cgaatctctt taattttttg
    32821 accaattaac atcagacgcc tcctcttcta cctgcttcga aaaatactgt gaaacttaaa
    32881 aaattgtaac ggctacatct ttcctactca taagatttca tagcttcttc cacttctgcc
    32941 aaagtaaccc caaacaactc taggcgtttg aggagttgct tgccgttaga atagccgatt
    33001 cggagagtct ctccgagata ttctctacgc ttacggctgt ctgcccctgc tagaaaacca
    33061 aggcgaatca aatcgctacg actaatgtca aactgactct catgttcaaa ttgttctgtc
    33121 acctgagcta gagccgtttt caggtcttca tagctggcat gctcaattcc cagagaacgc
    33181 cccttggtct tggacttggg aacagcttca tctcgcttga gaaaggcatg ctgaactgtt
    33241 ggaatggccg tcataatcat gcgccgaatc cgctccccat taaaatctgg gtctgtaaag
    33301 acaatgactc catgacgttg gtgtagacgc tgaatccgct ctatgtcctg gtcattgatg
    33361 gcagaacctc gagtctcata ggtctccaca tcgaaataac gcttgagatt gaccgtatca
    33421 tcacgacctt caaccacgat aacttgggaa attctctctt tcattacttg ctgtccaatc
    33481 caaaaatgcg ttctgcattt gcagtcgttg ctaccgccag ctcttctgtc gtcataccac
    33541 gcaagtcagc gataaagtcg accacatagc gagtataggc tgttttattt tcacgaccac
    33601 gcttgggtac aggtgctaag taaggcgcat ctgtttctac caacatcttg tccaaaggta
    33661 actctttagc tgcttcttgg aggtcagttg ccttcttgaa ggtcaccact cctgagaagg
    33721 aaatggtcat accaagatcc acaaacttct ctgcccactc aagcgtccct gaaaatgaat
    33781 gcatgatacc accacgagga ccaacgccct cactcttgat aatctcatag gtatcttcca
    33841 gcgcatcacg ggtatggaca acaaaaggca aatccaagtc cttagatagc cgaatctgac
    33901 ggcgaaaaac ctgctcctgc acctctttgg gcgctgtcat ccaatggtaa tctaagccaa
    33961 tttcacctaa agccacaacc ttgggatgtt ttaacttatc caacaagtaa gcctcaactt
    34021 cctctgtata agtaccagct tctgtaggat gccaaccaat agtcgcatag agctgctcat
    34081 actcatctac caactccaag gcacgctcaa tcatcggttt atcaaaacca acaatattca
    34141 tctgtatcac acccatctca gcagccaagg caatttcttc tgcctcacga cctgcaaatt
    34201 cttctacatt caagtgtgta tgtgtatcaa aaatcatctc ttctaacctc gttttctatc
    34261 ttctattata ccaaaaaaga ggaggggcac ctaatttttc ggtttcccct cctctcttca
    34321 atagagagct attctgctat cttttctatc cgatattgcc catctcctat tccacagtta
    34381 gagacagaag agattggcta cattgataga atattcctat tcagctaaag tatgtgatta
    34441 tcttgggttc tcacttttct cacccatcac taggattgat gacttctcaa aatccccctt
    34501 ataatctaac tttaagtaga gaatagaatt ttctagctgt tctattttct acgtctagtc
    34561 tttcttccta gcaaagcaaa accacttgtt gccaccacta gaccaagact agcaagtgct
    34621 gcacttgatg ctgaacctgt gttaggtaat tgtttgccag caggtgactg gtaggtaaca
    34681 tcttgcattg ttcctgcagt tgcttgcggt gcacttgttg tcttaggagc agcattagga
    34741 gccactagtc tcttaggaac tgtaaccatg gcaatggctt gcactccaat cgtttctgct
    34801 tccttcacat cttccatagt tttcgcattt tcaatctctt tgagagctgc ttgtttttct
    34861 gcttccactc ttgctaaaag ttctgctttt tctttatcag aaagcggtgc gcctttgatt
    34921 tcatcctgct tgtccttggc tgctttttca atggcatttt tagctgattc tttttcagta
    34981 gctaattgct tagaagcttg tgattgagct gagttttgtg aacctgtgtg agctgatcca
    35041 cccgcctggc taccaccgcc ttcattcgca ttagcatctg agcttccaat attgcctccc
    35101 ttatctccac ctggtgtagt ttctagctta tactctggtg taacttcttg agttacagat
    35161 tcacctttcg cagattgttg aactgtatct tttcctagaa tcgtcactac tgaaccatct
    35221 gggaatgtga ttgttgctgt accatctcca gctacattga ttgtcgctcc gtctaatgct
    35281 gaaccatttg cttgtaaaat agcaacctta actttttctt catctgttaa atgagttata
    35341 tcttttacat ctactctttg agcaggtgct ttaacagttg atttttcagc agtcggttta
    35401 gtgctatctt gtgcttttgg atcttgtgct accaattgat ttcctggaat tgtaatagct
    35461 gaaccatctt taaagacgat tgttgctgta ccatctccac ctacttcaac tttatagtaa
    35521 aataaaataa taacaggaca aatcgatcag gacagtcaaa tcgatttcta acaatgtttt
    35581 agaaacagag gtgtactatt ctagtttcaa tctactataa catcgcttcc gaatccattt
    35641 gcatctactg aactttttta caaaaataaa aatcagtaga ctcgagttcc tactgatttt
    35701 tgatagaatt cgtttggatt atgcagccaa aactttgcgt cctttacgac gacgagctgc
    35761 caatacgcga cgaccatttt tagttgacat acggttacgg aatccgtgtt tgcgcgcacg
    35821 acgaagttta cttggttgat aagtacgttt cacgatgaat acctcctcat agattttgta
    35881 ttcgtttagc cggctataaa gtgatcagtt actaaacata ctttactatt ctatctgatt
    35941 ctttcacttt tgtcaatagc tctaggcaaa tgtttccagc tttttcgaat gcaagcccta
    36001 tctacgatac tgtttcaaga aacgagtcat cttttcttgg atttgggcta actcatcaac
    36061 acgaggaagg taaacgatac ggaagtggtc tggttcctgc cagttaaagc ctcgaccatg
    36121 aaccaagaga accttttcct gcttcaagaa atcaaggaca aactgctcat catcatcgat
    36181 acggtacata ttgcggtcga tttttgggaa gatatagagc cccgccttgg gtttaacggc
    36241 agacaaacct ggaatatctt gaatggcatt atagatgaaa tttctttgct cgtagattcg
    36301 tccaccagga agaagcaatt catcgactga ttggtgaccc cccaaggaag tttgtacgac
    36361 ttgttgggcc aaaacgttag agcaaaggcg catattggac agcatattga gcccttcgat
    36421 atagccctta acatgagtct tagggccaga caagaccatc caacccacac ggaaacctgc
    36481 tatgcggtgg gattttgaca gaccattcat gctgacacag aagacatctg gtgccaagct
    36541 cgccacaggc gtatgcacat gtccgtccat taccatgcgg tcatagattt catccgcaaa
    36601 gataatcaaa tcgttttgac gggcaatctc aataatctcc agcaagagtt ccttaggata
    36661 aagggctcca gttgggttat ttggattgat aaggacgatt gccttggtat tggaagtgat
    36721 ttttgacttg atatcgtcaa tatctgggta ccattcaaca gcttcatcac agatatagtg
    36781 aacggcattt cctccagcta ggctgacagc cgccgtccat agaggatagt ctggcattgg
    36841 cactaagacc tcatccccat tgtccaaaag cccctgcatg gacatgacaa tcaactcact
    36901 gacaccattt ccaaggtaaa tatcatcaat atctacgttt gggaatttct tcagctggca
    36961 atactgcatg atggccttac gggctgagaa aatccctttg gagtcagaat agccttcact
    37021 atcacgcgca ttcataatca agtcatgaat gacctcgtct ggcgctgtaa agccaaattc
    37081 tgctggattt cctgtattca gacgtaaaat cttttctcca ttcgctcgca tccgcatggc
    37141 ttcttccaat acaggaccac ggatatcata agcaacatgc tctaacttac tagacttgtt
    37201 atattctttc atcttgtttc ctcaattcat caggatagta acattatacc actagaaaga
    37261 gaatgcgaca agtttactga aatgtgttac tagtttcgta tagaagaaaa accttgctaa
    37321 aggcgaggtt aagaacgtag agatagcagg tattttgcaa agacacatca cataccaaaa
    37381 gataaaccta gaaaaagcaa gcctagaaag gagtcataaa gaagattaaa catgaggaaa
    37441 agcccccata tcatcaagta atcccaacgc ccacttcgtt ttgcaactag aaataagatt
    37501 agatggtaga gtacatgaaa gactaaaaat ccaataaaac ttggataaag aagcggtacc
    37561 agactctcta attgacagat catgatcact tttaccaaga ctgaaactag gataattcca
    37621 taataaagga aatttgattt ttgaaaagag tttttcatca ttctcctttc ctcctatcct
    37681 ttcttttatt ttatcatata tttatataga gtttaagccc taatattctt ttgaaaaata
    37741 ctttttttgc tttacttcta tagtgaaaag gtttacaatt atagtaagaa aatttcagga
    37801 ggtttcatta tggcacaacg ttaccaaaat atcatggtcg caatcgatgg ttctaaggaa
    37861 gcggacttgg cttttgtcaa gggagttcat tctgctctac gaaacgacgc taaactcacc
    37921 atcgcacatg tcattgacac acgcgctctc caaagcgtat ccacctttga tgctgaagtt
    37981 tacgaagaac tccaagtcga cgctgaaagt ctgatgaaag agtacgaaaa acgtgctaaa
    38041 gatgctgggg tagcagatgt tcatatcgtc attgaaatgg gaaatccaaa gaccctgcta
    38101 gcacgtacta ttccagatgc cgaggaagtg gacctcatcc tcgtgggcgc aactggtctc
    38161 aacgcctttg aacgcctctt ggtcggctct tcatctgaat acatactccg ccatgctaag
    38221 gtcgatttgc tggttgtgag agaacaagaa aaaaccttat aatcacaaag aaaaggagcc
    38281 cctagctcct ttttgtttac gatttatttc tctctttatg gcgttcgtaa gccttgagct
    38341 ggcgatgcag ttccttttta atagcaggtt ctggagcata tttttcttcc caattatctg
    38401 gttttaagat tttatgggtc actggatcaa aatgagcctt gccatctgga aaaattttcc
    38461 ccatattggc ctgatggaca atatcaaaaa tacgttctgg gtccaccccc atcaagacaa
    38521 aactgccgta ggtgaagtaa agcgtgtcaa tcaaggcatc cacttgccct atcaaatctt
    38581 gctgagcagg tgtcttcttg gctactttac ctgctgcctt atcaagggcc tgatgaagtt
    38641 gcgatacagc ttgaccaaaa tcttcttcag aaggactggc tgctcgaaca aactccacca
    38701 attcttctat tttaaaacca gccctatggg ttgcaccctc taaatcccaa gctcgaggtt
    38761 cttcttgggt tcgttcatcc atcatgtggt ggaaggtctt gaccttattg aaatgatagt
    38821 cacggctgac aaagactttt tctgaagaca aaacaccaaa atgttccaag gccttgtgga
    38881 tcccatcttg ttgattgcta gtggtaatgt gcttggcagc ttccttgaca ctgctactac
    38941 catttcccat agcgaccgac ataccgacgc cagccagcat ttcaaggtca ttatctgagt
    39001 caccaaaagc catgacttgg ttgaggtcaa agccatattc tttcccaact cggcgaatgc
    39061 cttctaattt agaatttccc tgattgatga catccgatgc aaaaggattg ctacgtgtca
    39121 atttcaagtc ttcaaaatca gctgccgcct tctcagattc ttctggtgtc atcagcatca
    39181 aaacttggta gataggctga ttcatcaggt gaagcaggtc ctcttccttt tggggaacaa
    39241 ccttgctgac catgcgatta aaagactgac tcaccgtccg agttaaaaca gagggaacga
    39301 agcgactaat tcgttgggaa aaagaaccca gaccaaagga catgatttta gaacccaaca
    39361 tggcatcctt ggtccctaga gcaatctccg tgccctcttt tttagcatag ctaattagat
    39421 ggcgcaaatg taacttggaa atagggctcg tgaacaagac tctgtcttta ctaaagatat
    39481 actggccatt ataggttacc gcaaaatcca gatccaaatc gtccatcaat tccttaacaa
    39541 aaaaaggtcc tcgccctgtc gctacgccaa ctagtacccc ttgttctttg acaatcttaa
    39601 tcgcgtcctt agtggatttc aaaacactct tgcgattgtt gaccaaggtt ccatcgatat
    39661 caaaaaaaac agctttgact tccatcctat tccaatctcc ccttttgtga tacaatgatt
    39721 ataccacatt tcagaaagag tgagtaaatc atgcctaaga aaatccttgt tttacatacg
    39781 ggtggaacta tttccatgca ggccgatgct tctggcgctg ttgtgacgag ttcagataat
    39841 cccatgaacc atgtgtccaa cccacttgaa ggaatccaag tccacacctt ggactttttt
    39901 aaccttccaa gtccccatat caaacccaaa catatgctgg tcctctacca gaaaattaaa
    39961 gaggaagcag ataactacga tggagtggtg atcacacacg gaaccgatac tttagaggaa
    40021 acagcctatt tccttgatac catggaagtt ccccatatgc ctatcgttct aacaggagcc
    40081 atgcgtagct ccaatgagct cggtagtgat ggtgtttata attacctaag tgctttacga
    40141 gtggccagcg atgacagggc tgctgacaaa ggagttttgg tcgttatgaa cgatgaaatc
    40201 cacgctgcca agtatgtcac caaaacacat acgactaatg tcagcacctt ccagactcca
    40261 acacatggcc ccctcggtct caccatgaaa caggaaatcc tctacttcaa aacagctgaa
    40321 cctcgtgttc gctttgacct tgatcacata caaggtttag tccctatcat ctcggcttat
    40381 gctggtatga cagatgagct gattgatatg ctggatttag aacacttgga cggtttgatt
    40441 atccaagcct tcggagctgg taatattccc aaagaaacgg ctcaaaaatt agaaagcctt
    40501 ctgcaaaaag gaattccagt cgctctggta tcacgatgct ttaacggtat tgccgagcct
    40561 gtttatgcct accagggtgg gggcgtacag ttgcaaaaag caggcgtttt ctttgttaaa
    40621 gaactcaacg cccaaaaagc tcgcttgaaa ctcctcatcg ccctcaatgc cggactaaca
    40681 ggacaggctt tgaaagacta tatggaaggc taatactctt cgaaaatctc tgcaaaccac
    40741 gtcagcgtcg ccttaccgta tgtatggtta ctgacttcgt cagttctatc tacaacctca
    40801 aaaacatgtt ttgagctgac ttcgtcagtt ctatctacaa cctcaaaaca gtgtgttgcg
    40861 cagcctttaa ccagccgcct agtccgctct atggtattca ttaagtcaac atctcttgtt
    40921 taagagcaca aaatcaggaa atcttctcga ttccctgatt ttttctattt acgttttcgt
    40981 gttgagctac gttctgtcaa accatgaggt aagagaactt cacgttcttc caactcttcc
    41041 ttatgcataa tcttggtcaa catacgcata ctaatggcac caaggtcata aagaggttgg
    41101 gcaatcgttg tcaagtttgg acgggtaaag cgtgagattt gtgaatcatc actagtaata
    41161 atttcaaaat cttctggcac agaaacaccc ttatcagcca aaccgttcaa gactcctgct
    41221 gccaactcat cacctgtcac aactgctgca gttgcatttg atgaaatcaa acgctctgct
    41281 aaggcgtaac catcatcata gctatattta gattcaaata ccaaaccctc actataagtg
    41341 attcctgctt ttttcaaggt ttccttgtag ccaactaaac gaaccttacc attgatgtca
    41401 tccactagcg gaccgctaac gaaagcaata cgctcatttt ctttagcaag gtaactcact
    41461 gcatcaattg ttgcttgctt atagtcaata ttgacacttg gcaactggtg ctcaacatcg
    41521 acagttcctg cgagaacaat cggagtacgt gaacgcgaaa attctgagcg aattttatct
    41581 gtcaagtgat aacccatata gataatgcca tctacctgct ttgaaaagag ggtattgaca
    41641 acagaaactt ctttctcgtt atcttcatcg ctattagcta ggacaatatt gtacttgtac
    41701 atttctgcaa tatcatcaat ccccttagcc aaactcgaaa aataaccatt ggtaatattt
    41761 ggaatcacga caccgacagt ggttgtcttt ttacttgcaa gaccacgcgc aactgcattt
    41821 ggacgataat ccaaacgatc aattacctct agcacttttt tacgggtatt ctcttttaca
    41881 tttttattgc cattgaccac acggctgacc gtcgccatgg aaacacctgc ttcacgagcg
    41941 acatcataaa tggttactgt atcatctgca ttcattcctt ttcctgtcct ttctatctca
    42001 cacattcttt tacaagtaga ggtactgatt gaagctctat atctacttac aaaagtgaag
    42061 atgtgaaaat ttcgttttca tatttctact tattccattc tatcactaat tgtaaacact
    42121 ttcaagtgtt ttttgaagat tgattgaaaa aatttcatag aaaacctagg tttagctcct
    42181 tgctaccacc ttagactaaa caaaaaggag gaaactaagc cctcctaaag ttatagtaaa
    42241 atgaaataag aacaggataa atcgatcagg acagtcaaat cgatttctaa caatgtttta
    42301 gaagtagagg tgtactattc tagtttccat ctactatagg tattgttcca ttcactaccg
    42361 tcaattttag cacatagtct tcatgaaaat attatatcat cataaccaac cagattcttt
    42421 tgcgatatta gctgcctctg ttcgattacc agcatccagt tttgaaagaa tattggtgac
    42481 atagtttcga atagttccgt ttgagaggta aagctgatct gcgatttctt ggttggataa
    42541 gccccgggcg attcccttta agacagcaat ctcttgttct gtcaacggat tgggacgggt
    42601 catcaccact tccatcaatt caggcgaata ctccttgcgt ccttcgagga cggtgtgcaa
    42661 ggtttgcatg aggtctgcaa tgcttcgttc ctttaataca taagcatcca ctccagcctt
    42721 gaccgcacgt tcaaaatacc cagcacgctt gaaggtcgtc accacagcca cctttgtttc
    42781 aagcctttct gatcgtatcc actccaagac ttcaagacct gtcttaacag gcatttctac
    42841 gtcaaggatg gcgatatcta cagactcctt ttctaatagt tggattgctt cttgcccatt
    42901 cttggcttga aggacagact ccacatctgg ttgaagcgtg agcaattgac acatggcatc
    42961 tcgcaacata ctttgatctt ctgcgactaa tactttcatc ttagtttctc tccttataag
    43021 gtagtcgaac ttgcacttcc gttggatgtt tctgactgat tacacttact tctcctgaaa
    43081 atggaaaaac acgatctcgg actgtatgga gctcatctcc ttttagaaaa gcaaagccgc
    43141 agccatcatc acttactgtt aaaatgagtt ccttctctgt ccgttctaat tttaagtaag
    43201 ctttagacgc tttggcatgt ttgatgatat tggtcaccaa ctcaagcaaa atcatagaag
    43261 ccattgaatc caattcttga gtaaggctag cagtatctag ttggttatct gtttccacct
    43321 caattccagc aatttctaac atctttttca cagtctctag ttcggatgtc aaagttctag
    43381 acttaagatt ttccacaatg gttcgaactt cacacattga ttctttgcta atttgctgta
    43441 tttctcttaa ttccttttcc acttgtggat aagcctgcat ttgaaatagc tgcaaggcta
    43501 gatctgtctt gacactaagc atagcaaagg tatgtcccag actatcatgc aaatcctgac
    43561 cgatacgatt gcgctcattt tctgctagca atagatttat ctgggtattt tgcttgacct
    43621 gagcttcttt caaatcctcg acaaggcgaa ttcgaaccga gcccaaagtc atcaaatcga
    43681 caaaagtaag aattacaagc atatagacta gaaactcaac ttcgattctc tgaaaaatca
    43741 aaagtcgccc cacaacaagg acttgagcaa ggagaaatgt ccatacatgt aaagacttta
    43801 aactacgtac gccaaaatga taaattaaga gattggaaag gaaaaagaaa aaccagatat
    43861 aattcccagc aacaaaggcg gtattcccag ctacatagac cagcatgagc ccccagaaaa
    43921 gccaagatag gcgctggttc ttagttatta aaacacccaa atacgtcact acaaatagaa
    43981 tatcaaccaa taaatgccaa gcaggaagct ccccaatcac tacaggtagg atgggaaaaa
    44041 gcataaaaat caaactggtc caaaacatat agtgtatgct tttcagtctt tcaagcatta
    44101 agcattctcc ttatgacctt gaaggtaaat agtcaaacca aataaaactg ctgaaaaaac
    44161 aagtaaataa actgtggctg atagattgat gtcaccctcg tttaagaagg tcttgagcaa
    44221 ctccatcaat tgataggtcg ggagacactt accaactgct tgcatccagt ctggaaataa
    44281 agaaatgggc atccagagtc cgcctaaaac agccaatcct agataaagaa gattgcccac
    44341 aacagacatc agctgactag ttggtaagag agtcaaggtc aagccaagtg ctacaaaagc
    44401 aatactcccc acaatcagca aaatcgcagc tccaacccat tttactagag gcatgtctac
    44461 acctcttaca aaatgtccaa ctgtaaaaac aaccagaatt gagaccaaat aatcaaccag
    44521 catacttgtt atctttgata gataatattc taccatattt acagggctat gacgcaatgt
    44581 tttctgccag ttgttcatct tatcggtatg taaaacagct ggaaatgaga ggatagttgt
    44641 cgacatcatg gaaaaggcag tcatggagat gaggtaatca cgcataaaat tcgcgagttc
    44701 acctggtgtg tcctgataga taccagaaaa aaataaatag aaagccgtcg gcatccctac
    44761 cgacaataga taatagatta attgtcgttt ggtcaataaa aattctatct tactaagtgc
    44821 tatccatcgt ttcatcttag ttatctccct tctgcgtctc ttcaaagatt gtattcaaca
    44881 aactacgatt attaacttcg atttcttgca tcctacatcc tgcttgggct aatagttccc
    44941 agaaagcatc tgcttctcga gtgactactt gtaaagaatc ttgctttagg gtccagtttt
    45001 caaccaaatt tgactgctct acgacttcct tgtaagctat aggaaggata aagtgctttt
    45061 ctatttcctc gctacgcata gctagaggcg tcgtatctcg aatcaactct cccttattta
    45121 agagcaaaat gcggtctgca gtgtgttcca cttcctcaat ataatgggac gaatagagaa
    45181 tggtaactcc ctgcgctttt agatcctgaa caatttccca aaaacgttgg cgggttgagg
    45241 tatccatggc cgcagttggc tcatctaaaa agacaagttt tggtcggcca atcaaggtca
    45301 agacaaaaga gaaaagacgc ttttgcccac ctgacaattt ttctgccaat tgctctttct
    45361 gttgcttgtc aaactgcaac agttgatcga tttcctggtt gctcaaggga tttggataaa
    45421 tgctttgaaa gaaagcaacc aactctttga cctttaattt ctgaacgatg acattttctt
    45481 gaggcagata acctctaata tagtctaact gagaactcgt cactgacaag ccttggatgg
    45541 atacttgacc gcttgtgacc agtttatctc caagcagaca gtccaagagt gtggtcttcc
    45601 cagcaccatt tggcccaatc aaggcgacgc attcaccttc agctacctca aaggaaatat
    45661 ccttcaaaat agcctttccc ttgatgtttt tatgtaatcc ttgaacctta atcatgtcca
    45721 tgatattctc ctttcaacca ctccattccc ataggaaagg cgataaaaat cataaatcct
    45781 agtccccagg caccacggat gaattggcga agcaaggctt gatcaaacca acctgtaaac
    45841 atttctacca accataccac tagtgatagt ccaataaaaa gatagagaaa cgcttttttc
    45901 atttttcaaa ctcctttttc acatctgaga ctaatttcaa accttctcgg ataagccagg
    45961 acatcattcc aaatcctgca aatagctccc aaggaaaatg atagaaatct tcatccaatc
    46021 ctgagaacat gagataagtc atgactcctg ctgctactaa actcattgcg acaatcattt
    46081 tatttttcat ctcttcttcc tccgtttcat acttcaatta tagacttttg aagttggcgg
    46141 agctagatgc ttctgtcact agaaaatatg acaaatgtca taaaaattct gtacaaaaca
    46201 agcaagatac actatataat aaaacacaag tagaaaaaat ctaaggcagc tttcaaaaga
    46261 gatatcaaac ccaattcaca ccataatgta aactaatact tatttaaaat caaaaagagc
    46321 ggaaattttt atcgcacaaa cacatatatt ataagcagag cgaaaaactc ttcaattact
    46381 ttcttaaaag tttgtaagaa ttatacaatc tgttaaattt taatttatgt acctaaacta
    46441 cagtattcat tgaacaaatt aggaaacaaa aaagtatacg ctgctaaaat gaattactga
    46501 aattcaaaaa agagagaagc aaactgattc tctcttaat
//
LOCUS       DBEJKC010000009        44816 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.009, whole genome shotgun sequence.
ACCESSION   DBEJKC010000009 DBEJKC010000000
VERSION     DBEJKC010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 44816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44816
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.009"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(468..2195)
                     /gene="ezrA"
                     /locus_tag="ACL3G6_000505"
     CDS             complement(468..2195)
                     /gene="ezrA"
                     /locus_tag="ACL3G6_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HGR0545086.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAESYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2277..4223)
                     /gene="gyrB"
                     /locus_tag="ACL3G6_000506"
     CDS             complement(2277..4223)
                     /gene="gyrB"
                     /locus_tag="ACL3G6_000506"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HGR0545087.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4238..4801)
                     /locus_tag="ACL3G6_000507"
     CDS             complement(4238..4801)
                     /locus_tag="ACL3G6_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0545088.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTSFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4886..5440)
                     /locus_tag="ACL3G6_000508"
     CDS             complement(4886..5440)
                     /locus_tag="ACL3G6_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1 family glyoxalase III"
                     /protein_id="HGR0545089.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGNLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5451..6674)
                     /locus_tag="ACL3G6_000509"
     CDS             complement(5451..6674)
                     /locus_tag="ACL3G6_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGR0545090.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPRLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6711..9161)
                     /locus_tag="ACL3G6_000510"
     CDS             complement(6711..9161)
                     /locus_tag="ACL3G6_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HGR0545091.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSCRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVVSLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9361..10290)
                     /locus_tag="ACL3G6_000511"
     CDS             complement(9361..10290)
                     /locus_tag="ACL3G6_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HGR0545092.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            10430..10717
                     /locus_tag="ACL3G6_000512"
     CDS             10430..10717
                     /locus_tag="ACL3G6_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HGR0545093.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10751..12085)
                     /gene="ciaH"
                     /locus_tag="ACL3G6_000513"
     CDS             complement(10751..12085)
                     /gene="ciaH"
                     /locus_tag="ACL3G6_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HGR0545094.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12075..12749)
                     /gene="ciaR"
                     /locus_tag="ACL3G6_000514"
     CDS             complement(12075..12749)
                     /gene="ciaR"
                     /locus_tag="ACL3G6_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HGR0545095.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12858..15404)
                     /locus_tag="ACL3G6_000515"
     CDS             complement(12858..15404)
                     /locus_tag="ACL3G6_000515"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HGR0545096.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15527..15967)
                     /locus_tag="ACL3G6_000516"
     CDS             complement(15527..15967)
                     /locus_tag="ACL3G6_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HGR0545097.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15942..16811)
                     /locus_tag="ACL3G6_000517"
     CDS             complement(15942..16811)
                     /locus_tag="ACL3G6_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative PEP-binding protein"
                     /protein_id="HGR0545098.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLDRILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16789..17289)
                     /locus_tag="ACL3G6_000518"
     CDS             complement(16789..17289)
                     /locus_tag="ACL3G6_000518"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0545099.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(17300..17998)
                     /locus_tag="ACL3G6_000519"
     CDS             complement(17300..17998)
                     /locus_tag="ACL3G6_000519"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HGR0545100.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDAYKPLLEQTAQEIQEIFEINYMTPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(17991..18227)
                     /locus_tag="ACL3G6_000520"
     CDS             complement(17991..18227)
                     /locus_tag="ACL3G6_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018367459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HGR0545101.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFFMWSPTACDVLATDWVEVHD"
     gene            complement(18327..19253)
                     /locus_tag="ACL3G6_000521"
     CDS             complement(18327..19253)
                     /locus_tag="ACL3G6_000521"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HGR0545102.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19328..20143)
                     /locus_tag="ACL3G6_000522"
     CDS             complement(19328..20143)
                     /locus_tag="ACL3G6_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545103.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20147..20467)
                     /locus_tag="ACL3G6_000523"
     CDS             complement(20147..20467)
                     /locus_tag="ACL3G6_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGR0545104.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(20557..20703)
                     /locus_tag="ACL3G6_000524"
     CDS             complement(20557..20703)
                     /locus_tag="ACL3G6_000524"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545105.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSNHTYGRATLTWFEEI
                     FEEY"
     gene            complement(20753..22750)
                     /gene="metG"
                     /locus_tag="ACL3G6_000525"
     CDS             complement(20753..22750)
                     /gene="metG"
                     /locus_tag="ACL3G6_000525"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HGR0545106.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(22874..24133)
                     /locus_tag="ACL3G6_000526"
     CDS             complement(22874..24133)
                     /locus_tag="ACL3G6_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0545107.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(24135..24836)
                     /locus_tag="ACL3G6_000527"
     CDS             complement(24135..24836)
                     /locus_tag="ACL3G6_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0545108.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(24820..26019)
                     /locus_tag="ACL3G6_000528"
     CDS             complement(24820..26019)
                     /locus_tag="ACL3G6_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HGR0545109.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            26305..27651
                     /gene="gor"
                     /locus_tag="ACL3G6_000529"
     CDS             26305..27651
                     /gene="gor"
                     /locus_tag="ACL3G6_000529"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HGR0545110.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFNFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            27848..28384
                     /locus_tag="ACL3G6_000530"
     CDS             27848..28384
                     /locus_tag="ACL3G6_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HGR0545111.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            complement(28585..28800)
                     /locus_tag="ACL3G6_000531"
     CDS             complement(28585..28800)
                     /locus_tag="ACL3G6_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HGR0545112.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            28898..29218
                     /locus_tag="ACL3G6_000532"
     CDS             28898..29218
                     /locus_tag="ACL3G6_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545113.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(29249..29587)
                     /locus_tag="ACL3G6_000533"
     CDS             complement(29249..29587)
                     /locus_tag="ACL3G6_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP cone domain-containing protein"
                     /protein_id="HGR0545114.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(29599..30318)
                     /gene="trmD"
                     /locus_tag="ACL3G6_000534"
     CDS             complement(29599..30318)
                     /gene="trmD"
                     /locus_tag="ACL3G6_000534"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HGR0545115.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(30308..30826)
                     /gene="rimM"
                     /locus_tag="ACL3G6_000535"
     CDS             complement(30308..30826)
                     /gene="rimM"
                     /locus_tag="ACL3G6_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HGR0545116.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELTLFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(30856..31644)
                     /locus_tag="ACL3G6_000536"
     CDS             complement(30856..31644)
                     /locus_tag="ACL3G6_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR0545117.1"
                     /translation="MKRFEVSTEIGSLSVTYKKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGRNHHYLQWSESEKIAAIIRELSE"
     gene            complement(31748..32072)
                     /locus_tag="ACL3G6_000537"
                     /pseudo
     CDS             complement(31748..32072)
                     /locus_tag="ACL3G6_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654120.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
     gene            complement(32221..32460)
                     /gene="kphA"
                     /locus_tag="ACL3G6_000538"
     CDS             complement(32221..32460)
                     /gene="kphA"
                     /locus_tag="ACL3G6_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein KphA"
                     /protein_id="HGR0545118.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(32480..32752)
                     /gene="rpsP"
                     /locus_tag="ACL3G6_000539"
     CDS             complement(32480..32752)
                     /gene="rpsP"
                     /locus_tag="ACL3G6_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HGR0545119.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            32922..33131
                     /locus_tag="ACL3G6_000540"
     CDS             32922..33131
                     /locus_tag="ACL3G6_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545120.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMDL
                     LADDSLAGDIILLWRIQFGTFTTET"
     gene            33613..33825
                     /locus_tag="ACL3G6_000541"
     CDS             33613..33825
                     /locus_tag="ACL3G6_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545121.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            33909..34712
                     /locus_tag="ACL3G6_000542"
     CDS             33909..34712
                     /locus_tag="ACL3G6_000542"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGR0545122.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGNGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(34768..36309)
                     /locus_tag="ACL3G6_000543"
     CDS             complement(34768..36309)
                     /locus_tag="ACL3G6_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR0545123.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(36311..36793)
                     /locus_tag="ACL3G6_000544"
     CDS             complement(36311..36793)
                     /locus_tag="ACL3G6_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGR0545124.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(36793..37878)
                     /gene="rlmN"
                     /locus_tag="ACL3G6_000545"
     CDS             complement(36793..37878)
                     /gene="rlmN"
                     /locus_tag="ACL3G6_000545"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HGR0545125.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMTIGARHITVSTLGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDSVEQALE
                     LTELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(37899..38429)
                     /locus_tag="ACL3G6_000546"
     CDS             complement(37899..38429)
                     /locus_tag="ACL3G6_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HGR0545126.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(38585..39190)
                     /gene="sodA"
                     /locus_tag="ACL3G6_000547"
     CDS             complement(38585..39190)
                     /gene="sodA"
                     /locus_tag="ACL3G6_000547"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase SodA"
                     /protein_id="HGR0545127.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(39363..40400)
                     /gene="holA"
                     /locus_tag="ACL3G6_000548"
     CDS             complement(39363..40400)
                     /gene="holA"
                     /locus_tag="ACL3G6_000548"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGR0545128.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(40434..41369)
                     /locus_tag="ACL3G6_000549"
     CDS             complement(40434..41369)
                     /locus_tag="ACL3G6_000549"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HGR0545129.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(41922..43112)
                     /gene="metK"
                     /locus_tag="ACL3G6_000550"
     CDS             complement(41922..43112)
                     /gene="metK"
                     /locus_tag="ACL3G6_000550"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HGR0545130.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(43327..44670)
                     /locus_tag="ACL3G6_000551"
     CDS             complement(43327..44670)
                     /locus_tag="ACL3G6_000551"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0545131.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
BASE COUNT        13273 a         9803 c         8104 g        13636 t
ORIGIN      
        1 tagaatgtct tccaaacgag gaaactctcg taaacaaaga ggttttagag gcctatttac
       61 cgtggactaa agttgtacaa gaaaagtgca aataagaaat ctccagatta ggaactatcc
      121 gtgagttctc tagtctggag atttttcaat agacttcgtt attggacggt taccaagtta
      181 ctcaaagtac agatttgaag ctgcagataa gactgacgaa atcactttaa tactaaatga
      241 aaatcaaaaa gcaaactaag aagctagcct caggctgtac ttgagtacgg taaggcgacg
      301 ctgacgtgat ttgaagagat tttcgaagag tataaaacac tgttttgagg tggtggataa
      361 atcggctggg taaaaactca atctcaggag aaaatgaagt aaatctcccc gcaactatag
      421 aaaaagattt gattctgctc ctcacacaat aaaatctttt tcttttatta aaaacgaatc
      481 gtttcacgtg ttttctcata tgaggtaaca aagcgattag ttacaccagg ctctgccact
      541 tccaatgctt gagaaatctt gtcaaatgaa gcgtgataat caaattcttt ttcaaaaata
      601 tctaaagctt cgttaaatgc ttcttgaatg cgttcatcaa atgagcgata gcggttagaa
      661 tattgcaaga gttgctctgt caaagttgca tattgtacaa tattataagt ttccgtttct
      721 aaagcttcca tatcattcgt tgcaatttca agaactcggg taacagattc aatgttaatc
      781 attttttgtt ctaactcaac cattaaatcc tcggtattat tgcttgccgt aaagaataac
      841 ttcaagaaag tttgtggaat acctggcaga ttgcgttttt ccatgtatcg cttgatagta
      901 tggagacgat tgacataaac attggccttt tgacgtgcat taatatcatc tttctcaatt
      961 tgtgtcaggc gctcactaac tgaaatttgc tcatcttcaa tatcttttag ttgagtttgt
     1021 aaatcctcaa gattttcttc aagaactgaa taagcttggg ttggttcttc ttgattcgaa
     1081 gttacctcaa caatagctgc ctcaaaactc tctaattctg tctgaatacg acgaacatgg
     1141 cttgcagctg tctcaggaag taaataggtc ttgttcaaac gtgcaatatc ttctcccaat
     1201 aaagtattat tctctttcat atgttgaagg taagttggaa gagttgcaag tagattttcc
     1261 actactttct gagcagcaat ttctcgagta aaaatatcat acaaggcatt gatttcctct
     1321 tgtgcctgtc cattctcata ttcggcatta tccaattcca actgacgaat attctcttgg
     1381 tttttcttga atgcttcata aagcaagtgg aaacgcgctt caatatccgt ttcaacaaaa
     1441 tgataattag catcaattag tttacgataa ccggcttcca aatcctgtaa ttgatctggc
     1501 aattctgtag aaagcgtcgt aaccaaggct ggaacacgat ccacaatatg acttaaggcc
     1561 aaaatgtgat tttctgtatt atccaaaatc actgcggctt ccacagggtc acccgatgaa
     1621 ttcaaggtta caaattgtga aaattcagat tggatatttt ctaattgttt ttcaatttca
     1681 tccaaggctt gaccatactg ttctgaattt tcagcaactc tatgctgaag ttcctcaaat
     1741 aaatccaaag catgaagaac acgaccacta tttttagatt cttgcttctc taagtctgcc
     1801 aaagcattgc gaattgccgc aatatcttct tcaatcaaag taatttgact ctcaatttgg
     1861 tcaatttgat gactggcctt gagaaaacga aatgaatggt tatagctctc tgcttcaaag
     1921 agattatttt caatatcggc aaaagagttg agagataaat cgacccattt ttgattccat
     1981 tcacggaaag ccacttgact ttgtccaatc aagtgcatat tttttacagc ttctacttca
     2041 tcatttactg gaagattgta tagttcttct tttctttctt ctagtgcctc taatctcccc
     2101 tcgtttcgct tacgtagaaa gattgccact acataagcca gaactaaaat gactgcaatt
     2161 gcaaccatta aataaattag ttgtccatta gacatatcaa actccttttt tacttgaaac
     2221 aatcgtaacg attatatcat attttttaga ccaagggaac tacttctccc tattttttag
     2281 acatcaagtg tactatagac agcattttct tcgataaact cacgacgagg ctctactcga
     2341 tcccccatca acatatcaaa gattttatct gcttctgcag catcatctac agaaactcta
     2401 gccatcaagc gatgttcggg atccatggtt gtttcccaca gctgatgatc gtccatttca
     2461 cctagcccct tataacgctg aatagtcggt ttggtacgac cttcactata acgggctaaa
     2521 gcttcttgga gtttgatttc ttgatctgca cccggctgga tatattcttt aatctcgctt
     2581 ccaaccttga caccatagat tggtggttgg gcaatataaa cataaccagc ttctaggatt
     2641 ggtttcatat aacgataaat caaggttaaa agaagggtac gaatgtgggc tccatcgaca
     2701 tcggcatcgg tcatcaaaac gagtttttgg taacgggctt tcgaaacatc aaattctgcg
     2761 ccaaatcctg ttcccatggc tgtgaaaaga ctacgaattt cttcgttagc tagaatctta
     2821 tccatacttg ctttttcaac gttcaaaatc ttaccgcgaa ttggaaggat agcctgaaac
     2881 tcacggttac gaccagattt ggctgatcca ccagctgagt ctccttcgac gatgaagagt
     2941 tctgtttcag cagggttatt agaagaacag tctgctagtt tccctggaag gttggaaatt
     3001 tccaaaccag attttttacg tgtgacttca cgcgcacgct tggcagccac acgagccttg
     3061 gcagccaaaa ttcctttttc tacgatacgt ttggcaatct gtggattttc catgaggaaa
     3121 tcggagaagg cttcactgaa gaggcgattg gtaatcttga ccacttcgct atttcccaat
     3181 ttggtcttgg tttgtccttc aaactgtgga tttgggtgtt taactgagat aactgcagtt
     3241 aagccttcgc gaacatcttc ccctgttagg ttgtcttcat tgtctttcag taacttattt
     3301 ttacgagcat aatcattgat aacacgtgtc aaggctgtac ggaaaccttg ttcatgcgtt
     3361 ccaccttcat gtgtatgaat attattggcg aaactcatga cattttcatg gtaaccagtt
     3421 gtgtactgca tggctacctc aactgtgata tcatccatct caccgtctgt atagattggt
     3481 gtatcaaaga ttacatcctt gttctcgttg atatattcaa cgtaactagc aatcccacct
     3541 tcataatgat aatgcttggt ttgttccaaa ccttggcgct tatcagtgat agaaatttga
     3601 agaccgcgat ttagaaaggc caactcttga atccgtttat ttaatttatc aaaatcaaag
     3661 attgttgttt cagtgaaaat ttctgggtcc ggtgtgaagt gaaccgttgt tccagttcta
     3721 tctgtatccc caaccacctc aaggtctgca acaacatgac cacgacggta ttcttggtaa
     3781 tgaatcttac cgtttttatg gacatgaacg tctaattgag tggaaagggc attaactact
     3841 gacgacccca ccccgtgaag accacctgaa accttgtatc caccaccgcc gaactttcct
     3901 ccagcatgaa ggactgtaaa gacggtctca acagcaggac ggcctgtttt ttcctgaata
     3961 tcgactggga taccacgccc atcatccaca acagtaatcg aatcatctgg ctcaataaaa
     4021 acttgaatat ggctggcaaa tcctgccaag gcctcgtcaa ttgagttatc aacaatttcc
     4081 cagactagat ggtgaagacc ttcttttgag gttgatccaa tgtacatccc tggacgcata
     4141 cgaacagcct ctaagccctc taaaacttga atttgactgg catcataatc ctgtgcctgc
     4201 agatttttga tttcttctgt catcttattc ctttttctta tatgtctaat acttgtctta
     4261 aattcacgat actggtaaac aagtgggtat caagtcctgc agcttgacct gcttcgatat
     4321 caatcggccg atcaccaatg acaagaccag agctaatctg atacttttct cttaaataaa
     4381 gcatggattc gggatttggc tttctcttaa agcctgagct agaagtcacc acttctgtaa
     4441 aataagctgc tatagaggtt ttttctaaaa tttccaaaac ctgatcattt cgatgagaga
     4501 ccaaaaaatg acggccacct tgatttgaaa tgacttccaa taggtcagaa actccttcaa
     4561 ataaaatcgg gtgttcaagc tctctggctt cattttcctt gtacttttct aaaaaattct
     4621 ctaaattggg agcgaatgtc tcaatcgcaa aagaagtaga aacctttaaa gcttgataga
     4681 cactgtcatg gtcttgtgtg ataccataca gtgccaatgt ttcaacaaat gcagctgttg
     4741 aagtttcata attatccagt aaagttccac ctaaatccca gatgtaatcg tgatatttca
     4801 tacccttcat tatagcattt ttttatgaaa aaagcgatga tttccctgag ttttccacat
     4861 aaaaaacgag agaataactc ccgttttact gatttttacc aaagacatct cgatagagca
     4921 ttcctgttcg taaactctct gcgtcccctc ctagttgctc caccaactcg taggcaaagg
     4981 caagggctgt tgaaggaccc cgactggttg tcaactgacc atctaccact actgtttcct
     5041 tgacgtagtg accatcaagg atttgctctt gaacgccgtc ataacaagtg tatcgcttat
     5101 ttttcaatat ctctgcttga ttgagggcaa ttggtgccgc acaaatggct gctagtttct
     5161 tcccttcttg ctcgaagctt tgcaattctt gaatcaaggt ctgattatca cgtaaatgtg
     5221 cagaaccagg catacctcca ggaagaacaa tcatatcata gtctgataaa tttccatcaa
     5281 agacatgatc tgctcttact tggattgcat gcgaacccgt tacttgctct tcaaaaccaa
     5341 ccatatcaca tgtgatattg gctcgacgca agacatctac aactgtcaag gcttcaattt
     5401 cttcaaagcc ctgagctaac ataactgcta cttttaccat gattttctcc ttatttaatt
     5461 tgttttaata caaccttttt ccgtttgaat gggacttttc cgctcttttc ttcagctaga
     5521 ttagtctggt aactcatcga taaaagcaaa ccaacaccaa tcagattact gataatagct
     5581 gatccccctt gcgaaatgaa aggcaaggga atccccgtca aaggaagtag tccagtcaca
     5641 gcaccgatat tctcaaagat gtggaagagc aacatcataa tcaaacctgt ggaaatataa
     5701 gtgtagaact ggttatttga tttaagagta atcttcaaca tacggtaaat caacatgaga
     5761 tagagggcaa taaccaggac agagccaata aagccaaaat cttctgcaat aaccgtaaaa
     5821 atcatatctg actctcgaac tgggataagc agattcgaag cattaaatcc ctgaccaaat
     5881 aagccaccac tcccaatggc aatctgccct tgagcctgct ggtaagtcgt tgtttgggca
     5941 aactcaaagg gattgagcca agccaaaatc cgattgattt ggtaggtcgg cattccaatc
     6001 tggtgaagaa aagctcgtcc gtccttgcta ataaagatag ctaagaaacc agcaactcct
     6061 gttacagcag tcacaaatac tgggataata attttccaag aaacccctga taataaaacg
     6121 attcctgaga aaatggctac aaaaaccaaa gccgtcccca agtcactttg aagtgctaaa
     6181 agaactagga ctggaatggt aaagagaatc atccagaaaa ttaacaaaaa gtccagcgga
     6241 accgtgcgtc tccattcctt atgtttcttt gtaaattgga caatgacacg agccaacatg
     6301 aggatataag atatcttcat aaattctgac ggttggaata gggtaattcc atttattgat
     6361 acccagtttt tggcacccgt tgatgcaact aatcttggat tataaaatac aatcggcaag
     6421 atcataagtc ccaagcctaa aatatataga aagggggtca ccttccaaag aaattctgta
     6481 ttaaagagca tgaccacaaa accaatcaca agccccaagg caatccaggc gacctgctgc
     6541 cctaaaatgg gcaaaatatt attgggataa tcatgactaa cggctatata gatagccacc
     6601 acaccgatga ccagtagaaa aaatactggc aagagcaaac tgtaatcgac tcttgagtcg
     6661 agagaacgtt tcatatatac taaccttata ctttcataca atactattta tcaaagttca
     6721 ttaaaaaatc tatcaatagc ctcgtcaact tcggatcgag agatggtttt aacagtcgct
     6781 tcttctgcta gagatactac tatttgtttg ccgtatcgtt ttccgacgat tctcctatcc
     6841 aaaataagag ttaaggaacg ttggtattca cgtctcatac ttcttcccaa agcctgtttt
     6901 aaacgaataa tggccattgg caattgataa tcataaaagg catttttccc ttcttgattc
     6961 agttcttgat taatcttttt cgtcaagggt tcttgaggat tttggaaagg aagcctcggt
     7021 acaacttgaa tcacaaaagg atggcttgaa aaatcaactc cctcccagaa acttgctgca
     7081 ccaagcaaga tttgttgttc acctttttca aagcgtttct ttagctgatg aacatcccca
     7141 tttttatact gggccaagtg gctaactgta agtaaatccg atactgctag aagcatgtct
     7201 ttagcggtaa agagaaccaa aatcggttgc tggaaagctt gaatttccac tagtaaagca
     7261 gctacctctc tggcatagac ttctaaggag gtttctgtta ccagagggaa atctttgacc
     7321 atgaccactt cttgttcctg ttttccccga gattcaatct tgacaaattt ggcttcagga
     7381 tagcctaaaa ggtctgccaa agaaaccctc tgactaatct caagagtagc cgatactccc
     7441 aagacttggc aactctcagg aagtaaagag gacagaagag tacggcatga ttttgtagaa
     7501 gaaatctgaa ttttcttttg actcgtttca gttacttcaa gccagtaatc accttcagct
     7561 gtaaaatagc gaaccagctc atcaaagcct tctacttcta attctgaaaa atactgatgg
     7621 agattgtcca gagaatctaa gatatttttc ctagatttac cagactgaaa ttgttctatc
     7681 aagtagagac actcaaagcg aatactttct agtatccgtt gttgaaccct gttttcttct
     7741 cctactaaag ccttatcaat taaatcgata atagattgta tatcgtaggt ctcttgaagc
     7801 agattttcta gagctaacaa aatcttttgg acttcatcaa taatcagtaa acggtcactg
     7861 acaaattcag gattatcttc aagtctggtc acgagatagg catgattagt cactaaaagc
     7921 ttgcaagtct ctgccctttc ttgactacgt ttccaaaaat cttccgtcac aaataagctc
     7981 tgggatgata aattcccatc atgacgaagg tctgctagaa aatgttggta acggtagagt
     8041 tgcccgattt catccaaatc tcctgtctct gtctcagtaa gccagaccaa gacttgcatt
     8101 ttaaagcgtc taaataagcg attttcatca ttttcctgca aggaatgata aaaggcatcc
     8161 aacttcagat aattttgtgg tccctttaag ctatgaatat ctgtatggaa cacttccttg
     8221 aggcgtttac cttcttcttc catgatttga ttttgaagaa tctttgtcgg aacactaaga
     8281 acaatttgtc gctctttgga ttgagataaa gcgggtaaga gatagccata ggttttccca
     8341 atccctgtcg gcgcttgaat cagagagaca ggttcatctt tcaatagcaa gccaacctct
     8401 ttagcaaaac tttcttgttc ctccctcact tcaaggttca acagagaaat atttttagaa
     8461 aagtcttgag atagttttcg tggctccaga gaagctgccg ttttcttaaa atacagacct
     8521 tgaacttgga ccaagtctgg agaactcagg atagattggt tgcgataagt ttcctcaata
     8581 accaggtagg actcatatag gagagcgtca gccatttcca gcaagcgttc caagagacct
     8641 ttaggaagct gggtcatctt ttcccgtaaa aaaagaagta attctgctgt agcttgggca
     8701 tctgaaaggg ctgtgtgtgc gtgtttaaga ggaattccta attctcgaca caaaatcggc
     8761 aagctatatt tttccagttc agggaaaaag acctgggcca attcgaccgt atcaacacga
     8821 gggtttctta gctcatagcc ttcaaaaaat aaattttccg ccaagagatt agcatcaaac
     8881 tgaacattat gggctacaaa aatcccatcc tccaccaagt caaatatttt tctggcaact
     8941 tgcgaaaaat caggtgcttg cgccagacgt tggtctgtca atcctgtcag ttctttgata
     9001 tgagcatcca agggttcatg tggattgaca tccgtcgtat agtgatcgac gatttctccg
     9061 tcctcaatca cgacaattcc cacttggata attttagcct tactacctgt gctagttgcc
     9121 tctaaatcca ccacaacata gcgattacca atcgttttca ttataaaaaa ttataccaaa
     9181 aaaagggcca tttggcacct gcaaacatag gataattttc aaactcaaga acactacttt
     9241 tcttaaaaat cccatcgaat agagcattct agcctgctga tttttgtaaa atagtgaaga
     9301 aatacgaaaa attgagagaa gaaatgtttg catcttcctt ctctcaacga atcatgtatt
     9361 ttatctaacc atgtcaggat cgtagtcata aaatcctgta tcaaggaaac ggtttttagg
     9421 gtgaagttta cgaacttctt catccagcaa gaaggcttga tcatggctaa agttgccctc
     9481 ttgaatcaag ttacgcgctt ggataaagag ttttgcaatc tcaacaaagt tctgaccagg
     9541 agtgtagagc ccttctagtt tccagcgagt aaagccatgc tccaccaatt ctgttaattt
     9601 gatcatcaaa tcaaggtcat tgttggcaaa gatatgggtc ccatgattat cttcaaaaat
     9661 ggaatagtgg ctctctggat cacttggctc agccaagaag aggtcacgtt tatgcgtctt
     9721 ttcatcatcg atatgtgtaa agttatagta gttttgcaag agtggacgtt tagaatgatg
     9781 gatgacgcta gcaccgtaaa ccaaaacttc agcaggaatt tccaaaatct ctggcatttt
     9841 gaaaagttca gctgatggaa tttcacgcgc caaaacagcc tcagatgcgc cagccttttg
     9901 tccccagaag ttaatctgac gactgctagt taccatggtt gaagcatcgt agatggtctt
     9961 aaatgaataa ccatcgcggt taactacgta aaagacgcct gcatccccaa tcgtaatata
    10021 gtctgtcttg atttcttcca agaagtctaa gaaaggcttg atacggtcca tcatatcttg
    10081 gtgcatgaga gcattgaccg caacgatcaa ttccttacca gcatcatgaa ccaacttagc
    10141 gatttcacgt aattggtcat aactaaaggt cgttggcaga cgaaggccaa aatctttctc
    10201 accgacatag atacggtcta cgccagcttc gagtagttgt tcaacttgtt caatactttc
    10261 agcagttgct gtaatgacaa tcttttccat aagaaaaatt ataccacatt tctccaaaat
    10321 catccatgct ttgaaaatga aaagggactt tattcttttt gtaacctttc tgtaataatt
    10381 ctctgccgaa aaaatgataa aataggtatg tactgttaag gagagaatta tgcccgtaag
    10441 aaaattacaa tcctatgagg tagactatca agaagaatta aaccagcagc ttcctcatta
    10501 ccaagcttat acacctgaag cgcaatctga tgccaatctc aaggaaatcc tattttttat
    10561 taatatcgct gttttttgta tctgtattgc tatctttagt tttatctttt tagcattaaa
    10621 attatcaact gctcttgcct ttgccgcagc aatcggattc agcttacttg ttttaaaagt
    10681 tcaacggtct attatcaaac gaaaacgtag aagataaatc caaaatatcg ccccagttgg
    10741 agcgatattt ttattttttc tttttagatg gtgtctgaat ggcaatcttc acttcaaaga
    10801 ttgttccctt gggtttatta tctttgacag taacagttcc ttttagagca tctacaattt
    10861 gcttggctag ggataatcct aaaccaaaac cacctttttg ccgggttcta gccttgtcta
    10921 ctcgataaaa acggtcaaaa attttctttt tatcttctgt cgaaataccg attccattat
    10981 cagaaacaag taaataaaga ttgcgatcgg tcgccgagat aagaaaatca atttcaccat
    11041 cctcctcagt atacttgacg gcattatcga aaagaatggt catcagttgt ttcagaagaa
    11101 gctgatctgt gacaattgtt cgatggatac gattttcaaa acggaagaca cgattatttt
    11161 ccgaagcaat catctcgtag tttgtgaaag ttgtattaaa aaagctagtt ggaacttctg
    11221 caagctccgg cttaatccca tcatctctcc gagctaagtt cagcaagctt gtcgttaaaa
    11281 aacgcatatt tcggacttct tccaaactcg atgcaatgct ttcgctcaca tccataatgg
    11341 tagcttctgg cttacgaaaa agggtctcta agcgattttg caaaactgcg agtggagttc
    11401 gtaactcatg actggcattt tccacaaaag actgttgctt ctgcatactc tcaagcaggg
    11461 gcctaacact gaccctagct agatagagac tggcaagtaa agacaaaatc cagaaactag
    11521 ccatcacgac cacaatcaat tgctcatgct tttgactagc ctgttccaac tgactggtat
    11581 taatcaagac agcagcatac ttgatattgg ttgaaaccga actaatattg gtctccatca
    11641 aaatcacacg atagatttct tcctgcccat agctattaaa aacctgaatc tggtagatat
    11701 gtcctagttc tttcttttct aacttaatct tatccaagcc caaaaatcga tttccagaaa
    11761 gaagttgagt aaagtcttta tcaaagagaa tgacttccgt attggaactg acattaggtt
    11821 ttatttctac tttactagcg tccgccctag cattttctaa atctttaatc tcttctgttg
    11881 ccctatttat agccagctga ataactgctt gaggattttc actcagtcca tgaagcttat
    11941 cgtccaccga agtataaaga ctcgaatgca tgacttgtaa aataatcaga gtcattgtag
    12001 aaaaaatcag ggtgaagaca ccgaagttgc ggataaaata actaaagtca tccgcatacc
    12061 atgttttttt aagtttactg aacatctttt aaaagatacc caacactacg caaagtttgc
    12121 aaattctctg caaaagtggt tccctttaat ttcttacgga cttttgaaac atagacttcg
    12181 acaaccgaaa tcgttgtatc actatcaaat ccccatagac ggtcaaaaat ctgcgtctta
    12241 ggtaaaatca cattttgatt ttgaaggaaa taaactagta aatcgaactc tttccccagc
    12301 aattcgacag gagtatcttc aactttaacg gtattggttg ataaattaac cacgatattc
    12361 ccataagtca aggtgttttc attaaacttc cctgaacgtt tgagaagagc ctgaatccgc
    12421 attttaagtt cttctaggta gaaaggtttg gtcagataat catccgctcc cagttcaaat
    12481 ccatgtccct tgtcatccaa actttccttg gcagtcataa tcagaactgg tgtcgtaatt
    12541 cccttttcac gcaattcttt taagacttgg aaaccatttt tttctggcaa catcaaatcc
    12601 agcaaaatca agtcatagac accactctca gcttcgtaga gaccttcttc tccatcaaat
    12661 acctgcataa catccgcaaa atcgtctaaa aagtcaaata ctgaatttga cagacctagg
    12721 tcatcctcaa ccaataagat ttttatcatg agaaactcct ccttattaaa actattatac
    12781 caaatttgcc ttaaaaaaaa ctcaactctc tgcattttac atgagatagc tgagttttct
    12841 ttttatttta ggcttattta tgcatttccg tattgaagaa caactgcttc gactgcagct
    12901 ttttcacggc taatcaagtc aacacgcgct gcaatttcct tgattcccat accgatgtta
    12961 cggctaagag caaggtcaga aagttgcggc tcaaagaact ccttgtattc cgccaagcgt
    13021 tgctgagtct taaatacatg agcaggaagg ataacaaagc tatcaaagct catatctcct
    13081 ccaagggctg ccttaatcca agcccagttt tcacgcgccc aagaccaagc tgttttctga
    13141 gttgcttgat gagctaggaa ttggtaatac caagcagaca agtcctgtgg tttgaccaca
    13201 aatttgtcct tccaagaagt aatcaggttt tggatattat ccgcatctgt actgtatgca
    13261 agagctgctg ccaactggcg tttaaagaca gcatctgttg cgtgagtata agtatcaaga
    13321 taaagtgcta acaagtcttt agtctcatga tgtttcatct cattaatcag aacttgtgag
    13381 cgaatagctg ctgggagtcc tgcaagattc tccttgtgtg ttgcgaagat ttggctagcg
    13441 acttgactag cttctgcatc atttgagcga atcatcatcg aaacagccag ctgacgaacc
    13501 aattcatcct catctgattc tccgtcttta gcttcaaaac caagacggtc atagttatga
    13561 cgagccaatt tagcaaccag tcctttgaag gctgtttcag catccgttcc ttcatcaata
    13621 aagcgctcaa gggctgaaat cacttgagaa acagctgaaa ccaccagata agactcttcc
    13681 ttagcaagtt tatcaagaac tggaagcaag tctgcataag aaatgtgccc tgcctcagcc
    13741 aacaaacgac gttcttgaac aatttgcagt ttgcttgtgt tatcaagtgt ctctagctca
    13801 gcaagaacag cttctaacaa gtctccttga tagtcggtaa tatagtgggc agtattttca
    13861 gtgttgagac gaagagctcc ttcattttca gcaagaagag ctgcgtagcc agggatttcg
    13921 atactttcag tttcgagtgt atcaggcaag cctttccagt tgctattgag gggcaccacc
    13981 cagagacggt tcttgtcttc gttctcaccg atgaagaatt gtttttgtga aatcttcaag
    14041 acatcatttt caactttaac agtaagaact gggtaaccag gctgttccaa ccaagaatcc
    14101 atgaaggctg cgacatcacg tcctgacgct tgaccaaggg catcccaaag gtcactacca
    14161 atggtgttgc tgtattggtg tttttcaaag taggcgtgca aacctttagc aaaatcagca
    14221 tctcctagcc aacggcgaag catgtgcatg agacggcttc ctttggcata gacgatagcg
    14281 ccgtcaaaga gtgtattgat ttcatctgga tgtttaactt cgacgtggac agactgaacg
    14341 ccatcagtag cgtcacgttc aagagcaaga ggtactccac ctgtttggaa atcttcaaag
    14401 atattccagc ttggttcgat ggtatccaca cagacgtatt ccatcatatt agcgaaactt
    14461 tcattgagcc aaaggtcatc ccaccatttc atagtcacga ggttcccaaa ccattggtga
    14521 gccaattcat gggccacaac aagggcaact tgttgacggc tagcaaatgt agagttctca
    14581 tcgacaacca agtaaacttc acggtaggtc acaagacccc agttttccat agcaccagct
    14641 gagaagtcag gaagggcgat gtggagagat tgaggaattg ggtacttaac tccatagtaa
    14701 tcttcgtaaa actcgataga gcgaacagcg atatccagtg agaaatcaag atttgaaagt
    14761 ggatgtgctt tggttgagta gacacctacc agggtaccat ttttagtttt agcggtcacc
    14821 ccttgcaaat caccagcaac aaaggccaac aagtaagaag acatgcgagg tgttgtctca
    14881 aacttccaga tacctgtttc cttacggttt tcaacatcga tttctggcat gtttgacaag
    14941 gccaattcac cttctgcttg gtcaaagcga agagagaggt caaaagttgc tttggcttca
    15001 ggctcatcca cacatgggaa agcttcgcgc gcaaaatggc tctcgaactg agtagacaag
    15061 acctccttct tgactccatc aactgtataa taagaagggt aaatccctgt catgttgtct
    15121 gtaattttac cagaaaaggc aagaaccaat tcaacttgac cagcctcagc caattcgata
    15181 tgaagggctt cattgtcatg gtcaactgta aatggacgag cttgacctgc aacttctaca
    15241 gaggtgattt ccaagtcttt ttggtggagg gagatgcggt cactctgtgc ttgaccagtg
    15301 atggtcactt tcccagaaaa agtcttggtc tcacgactca aatctaaaaa taaatcataa
    15361 tgttcaggaa caaattgctt aataaaatgt tcaactgctt gcatagtttt ctcctattct
    15421 aagtttaaga gctgctgctc ttcttcaaac aaacttatta tatcatattt tgcttgagaa
    15481 aaaaggattg gacagcgatt tccaaaactt tcttccttct aatagtctac agtgggtaga
    15541 ccttgcgaaa ttcttctaaa acaaccttgc tttcaggtgt aaaagtcagc cctacttcac
    15601 ccaaacagtc tgtgaaaaag tcctcatgaa cctggcgcca ataggcaagt gatttgtctc
    15661 cctcaccttc cttaaaggca tgttgcgcag aaacttgatt gaagagttca acagaaacct
    15721 ttgtaatttc gacaatgcag acagactgat tttgactatc taaaatgaca tcgaaggtcc
    15781 ctacttgggg aagtggttcg tcttctagta catagaggtc ataggctgat gctgttgctg
    15841 tcttttctcc tttaaacacc aaatccgcta aaaggtctgg ttcaactcca aaagcccaag
    15901 catcgatttc atctccgatc aaaggattga tttgcttgta tttattccac atttcttgcg
    15961 gtatcatggg tactcctttg taatttttta ctttcttctt ttatgtgttt aagatgatct
    16021 ggatggtcaa tctctaaatc aaaaatctct ggaatagaac tgtagtggat aatgcacttg
    16081 atacccaact gattcatttt ttgtatgaaa gaagtattca gatagcctgc tacagcaaaa
    16141 tcaatcttgt tctttcttgc tttatcctgc atatctctta gcatatctaa cattattgga
    16201 ctttccatat catgccattg actgtttctc atagtcgcaa aaacaaagga agtcaaatca
    16261 ttcattccaa ctacaatctt tgaaatgccc gtttccagta tcctatccaa gtcaaaatac
    16321 gctgacggta attcaatcat cgttccgact ttcccagtaa agccatactg acgcaatact
    16381 gtaatagctt gttttaattg gtcggcatca ttgacaaaag gaaagataag agatagattg
    16441 ggattggttt gataaacttc tgtaacgaca tgtgcttcag cctgaaattc atccaaacac
    16501 gccagtaaac gcctggttcc tctatagcca aacaagggat gcccttcgtc aaaaaactct
    16561 ctagtcccca ctaaacaatt ggcttctgta ttcgttaatt cagaaaaacg ataccaaact
    16621 tcttcatctg agtacaggga gcagatagtc tctagataat cttttacaaa ttgctgacaa
    16681 cttgctaata tgatgttttg attaagctct ctcaacaaat attccccacg aatcatgccg
    16741 acgtggtgaa atagttgagg ataaattttt tcaagaattt tttcgccact aagggcaagt
    16801 tgatttctca tcattcacct tccaattcat gtaagaagtc ttgtccagtt ctggaaatcc
    16861 taataattca gacttaacct tcaagactaa tggcgatgca ttttcttctg taatctcttg
    16921 aatatccatc caaatatatc caagtgaatc attcgcacca tcagacacag cttccgaagt
    16981 cgtaacttga ggtgcactct cattcatttc aacatcatac aaggccatga catggtgaac
    17041 cataaaattt gttaactctt ctctgacgaa aacatcgtag attcgaggat tagagtagct
    17101 tctaacagta aatcccgtct cttccataac ttctctagtc agcgtttccg tcagtccttc
    17161 accaagttgc tgactgcctc caggtagatc ataccgatgt tgataagggc ctctcgtttt
    17221 ttcaatgcag agtaacttcc cattttctaa gcaaacagcg tagactccaa agtgtttttt
    17281 gatttccatc caactcctcc tacttcaaag accagccacc atctattgtc aagatttgtc
    17341 cttgcatggc gctcgctttt ccacttgcta aaaaaagact aagctctgct atttcctctg
    17401 gctcaatcca gcgcttgatt ggggtttcac tagccaccca gtcagccaaa ccacctggtt
    17461 caaaatccgc agcggtcata gctgtcttga ctgctcctgg agcgatacca aagacctgaa
    17521 tcccagcttc agcatagtct agagccaact gcttggtgaa gccagccaag gcatgcttgg
    17581 atgaagtata ggcgtgacca cctccacctg ctaggctaga agcaatggaa cacatattga
    17641 tgatgattcc ctttttattt tccagcattt gtgtcaaata ataccgagtc aactcaacag
    17701 gagtcatgta gttaatttca aaaatctctt gaatttcctg cgcagtctgt tccaacagtg
    17761 gtttgtaagc atccaaaact ccggcagtat tacacaaaac atccacctga gggcaccagt
    17821 caaaaatagg ttccaagtcc aaggtcaaat ctctctgtaa aaagtgaaaa tcaccctcta
    17881 agagtggctt ttcaccttgg tcaactccat aaacttgata gcccttctct aaaaagaggc
    17941 gagcttgagc caatccgatc cctgaactca ctcctgtaat gagtacacgt ttagtcatgc
    18001 acttctaccc aatccgttgc caaaacatca caagctgtcg ggctccacat gaaaaaacct
    18061 tctccttctc cagacacgtt gattaagaaa taaggtgtca cttcaagtgc aagcccattt
    18121 tgctcgatgg tatcaaagag ttggacatag ttttcagcac ctccccaacc agttcgtaca
    18181 tattttttct tagcctttaa gccaggtaga atttcttcaa atgtcatgtt tttctccttt
    18241 aatgtcaata attctcccct tcattataac aaaaaaaccg ctttaaaacg gctttttgac
    18301 tgtgatttat ttacatcttc ttctacttac ggcaaattat tccctgcagc aagataaatt
    18361 tcataccatt cttttcttgt taagctaaag tttgccgctt ggctaacttc tctcaagtgc
    18421 ttaggatttg tggtacctac aactgcctgc atttttgctg gataacgcaa tatccaagaa
    18481 atggcaatag ttgaagaggt tactccatat ttaatagcta aacgatcaag tacttgattt
    18541 aaagcttgaa atttctcatt tccaacaaag ttccctttaa aatacccgaa ttgcaagaca
    18601 gaccatgctt gaatgaccac atcgtgtaat ttgcaatatt caaaaatgct gccatctcgc
    18661 atagctgctt gactatcttc catattaaca tgaaaagctg attcaaatcc tggagtaaaa
    18721 gccgcactca attgtagctg attaacagct aacggctgct tgacatcttt tttaagcaac
    18781 tccatcatca taggattttg attagaaact ccaaaatctc gaactttacc ttgtttataa
    18841 aggagatcaa aggcttctgc tacttggtca gattccatca aagcatctgg tcgatgaagg
    18901 agcaagctat ctagatgatc aatcttcaat ctttgcaaaa taccgtctac tgattttata
    18961 atatagtcct tagaaaaatc aaaataggta aattcttcaa tgcgaatgcc acatttggac
    19021 tgaatccaca tcttttctct taaatctgga cgatttttta ggacaagacc taacagttct
    19081 tcacaacgac cacgaccata aatatcagcc aagtcgaagg cattgattcc aacagaaagt
    19141 gctgtttcta caagctcttc aacttctttt acagacttat cttttattct catcattccg
    19201 agaacaattt ctgataattc tttgtcatct tgaccaagag ttatgtatct catcaaattt
    19261 ttctccttta atttctaaca ttcttccctt cattataaca aaaaaccgct ttgcaacggc
    19321 tttttgacta tacttcactc cattttatct tcttaaaccc acggaacaag acaaagattc
    19381 caataaagag gacagctaaa ggaataactt ttgtaaggaa aacatttgaa attcccatcc
    19441 actcataata acggagcaga gaacccacca caagatgggc aataatcata ctgacaaatg
    19501 gacgaaagac cgcttctttc caattccaaa taccgataac tagcgaaatc gtaaagacag
    19561 acaaactatc ccagggagcc ggaatataaa aggctccttc ttgtatgaag cttgccattc
    19621 ctacatatcc taaaacaact agaagaacta tagtcccaac aacaatgtaa gtgccaattt
    19681 tcattttagg agaatcttgg actaaacttc ttcgtaaaat tgtggccaca agtccaaatc
    19741 caatcagaaa aataagaagt tgccctaaaa atgtgagcaa attgactgtt aagagaggac
    19801 ctttagaaaa atcacttagt agttgataat aacgtaatac cgccaggaca agaattggcg
    19861 tcaaaaggga ctctttgata gaactgcgag gtgctccctt gagaatctct ttcattattt
    19921 ttttaggatt cttacctaga taatcctctg cactcatgcc atctcgttct gcttctgaga
    19981 aatctagcat catcaaatag atctgctctc tgagatagtc ttcatcatag agaaatccag
    20041 caagattaaa actttcccac aactcctcaa aatacttttg attctcctca gaaaactcat
    20101 gtagcaaagc gcttgtttct tcgtaatact tcattttctt catggtttaa cccccattct
    20161 taatcccttc tactttttga ctcaaatcgt cccattgttg ccaaaagact gagacacgct
    20221 cttctccttc tttcattaat gaaaaatact tccgatctgg accatctggc gacgggcgca
    20281 tgtcgcctct tatccattga tttttttcta acttttgcaa caaaggataa atagttcctg
    20341 gaacgatagt atcaaatcca gcctctcgca aagtctgaac caactcataa ccataccgct
    20401 ctttttgacc aatcatatcc aagacacaac cttcaagaac accttttaat agctgagttt
    20461 ctttcatcac ttctcccttc taatctattt tgtaatacct actagtaact tcacctatag
    20521 tatatcactt ctacactagt ttgtaaagca taatagttaa tactcttcga aaatctcttc
    20581 aaaccacgtc agcgtcgccc taccgtatgt atggttactg acttcgtcag tttcatctac
    20641 aacctcaaaa cagtgttttg agcaacctgc ggctagcttc ctagtttgct ctttgatttt
    20701 cattgagtat aaataaaaaa acagaactag tctgaactag tcctgtctac ttttacccaa
    20761 tcacacttcc atttggtaca gctggatcaa ctgtgagaag ggttaatttg ccatcatgtt
    20821 cagctgatag aatcataccc tggctgacat attttttcat cattttacgt ggtttgaggt
    20881 tagcaacgat ttgaactttc ttgccgacca attcttgttc atttggatag tattttgcaa
    20941 ttcctgaaag aatctgacga tcttctccat caccagcatc caagcggaat tgaagcaact
    21001 tatctgaacc ttctacttta gacacttctt tgacttctgc gacacggatt tcaaccttgt
    21061 caaagtcttc aaacttgatt tcatccttgt ttagtttgag ctcaacttcg tccggattcc
    21121 attctttttc gactgctggt ttattgcctt ccatttgttc cttgatatag gcgatttctt
    21181 cttccatatt tagacgtgga aagataggtg ttcctttggc aactacagtc acatctgctg
    21241 ggaagtcagc caaactcaag ttttcaagac tagaaacttc ttccaaacca agttgagtca
    21301 aaactgcacg actagtttcc atcataaatg gttcaatcaa gtgagcaact acacgaatgc
    21361 tggctgccaa gtggctcatg acacttgcca attggtcacg aagagcttca tccttggcca
    21421 agacccatgg tgcggtctca tcgatgtatt tattggtacg agagatcaga gtccagactg
    21481 cttcaagcgc acgtggatag tcaactgctt ccatgtgtgt atggaagtct gcgattgatt
    21541 gttctgcaac ctcagcaaga acatgatcaa attcagtcac accttctaca taggcaggga
    21601 tttgtccatc aaagtactta ttaatcatgg aaaccgtacg gttaaggagg ttcccaaggt
    21661 cattagccaa ttcatagttg atacggccga catagtcttc aggagtaaag gttccgtctg
    21721 aaccaactgg aaggttacgc atgaggtagt aacgaagtgg atctagtcca taacgctcta
    21781 ccaacatttc agggtaaacg acattccctt ttgacttaga catttttccg tctttcatga
    21841 caaaccaacc atgggcaatc aaacgatcag gtaatttaac atccaacatc ataagaagga
    21901 ttggccagta gatagagtgg aagcgaagga tatcttttcc taccatatgg aagactgttc
    21961 cattccagaa cttgtcaaag ttaccatgtt cgtcttgagc gtagccaaga gctgtcgcat
    22021 agttaagaag ggcatcaatc caaacgtaga caacgtgttt tggatttgat gggacaggca
    22081 ctccccatgt aaaggttgta cgagataccg ccaaatcttc caagcctggc tcgatgaagt
    22141 tgcgtagcat ttcattaagg cgaccatctg gcgtgataaa ttcaggatga gctttgaaaa
    22201 attcgaccaa acggtcttgg tatttgctaa ggcgaaggaa gtatgattct tcagaaaccc
    22261 attcaacctc atgacctgat ggagcaatac caccagtcac atttccagct tcatcacgga
    22321 aaacttctgc cagctggctt tctgtaaaga attcttcgtc tgatactgaa taccaaccag
    22381 agtattcacc caagtagata tcatcttgag caagtaagcg ttcaaagacc tgtgcgacaa
    22441 ctttttcatg gtagtcatcg gttgtacgga taaatttatc gtatgagata tctagtaatt
    22501 gccagagttc tttaactcca accgccattc catcaacata ggcttgaggt gtaataccag
    22561 cttcttccgc tttctgctgg attttctgac catgttcatc aagacctgtc agataaaata
    22621 catcgtagcc catcaggcgt ttgtaacgtg ctaggacatc acatgcgata gttgtgtagg
    22681 cagaaccgat atgaagtttc ccagatggat agtaaatcgg cgttgtaata taaaaatttt
    22741 tttcagacat aatttttcct ttccaggcaa atgaaacctg tttttctaac acttcattat
    22801 atcacatttt taatgaattt cgatagggaa atccatacaa aaacaagata gacgagtgtc
    22861 catcttgttg atctcattca taacgaaggg cttcaattgg atcaagtttc gatgccttgt
    22921 tggctggcaa gactccaaaa atcataccaa cactagccga aactgcaaga ctaaataggg
    22981 caactgggat tgatactcca acttctatac cttctattaa accttgcagt aacaaacctg
    23041 ctaaggcagt taaaccactt gcaattgtca agccaattaa gccacctaac aaggtcaaaa
    23101 tcatggattc aatcaaaaac tgaattaaaa tattggcacg tgttgcaccc aaagccttac
    23161 gaagaccaat ctcacgagtg cgctctgtca ccgaaaccag catgatgttc atgacaccag
    23221 ttcctccaac aaagagagaa atccctgcga tggaactaat aatcgtcgtc ataaaactaa
    23281 acgattgttg aatttctgca aatacaacgg actcatctgc cacctggtat tctccctgtt
    23341 gtaagcctgc aagctctgtc atttttcgtg ccagttctgg acccagagtt ggggttaaac
    23401 tggtatcatt cactcgaaag acaatattag ctatttcatc tacattaaaa ttcgcagcaa
    23461 gggagatatt ggtagtaata ggcaagccac caaacccata tatttttgat cttttagcct
    23521 ccggactagt ataaacccca atgacccggt aactaaatcc attgacttct acaaccttgt
    23581 taatagcctc ttgaggagat tcaaataaac taatggacaa ttcctcatct agcaaaatga
    23641 cacttgcaaa ctctttgaaa tcttgctctc tcagactacg acctgcaata atttcattct
    23701 taacagcgtc catgtaagtt ctgtttccac ctgtcaaatt agcattctca acctttttat
    23761 cttgataggt caagatggca ttcgttgaat tggttacata gtaactatcc actcccttca
    23821 gtttagctgc ctcttgaacc caggattctt gcggttttgg cggttcaaca ggaacttcct
    23881 cttcctttcc agaaaccgta aaagctgatt gtttctgagt aaaagaccca tctttacttt
    23941 ttttaggaga gaaaaagacg ctaatatttt tctgagattt agtcatatct ttattgactt
    24001 gacgagatag ggaatcaccc aaagccataa tcacaacaac tgatgaaaca ccgataataa
    24061 tcccaatcat agtaagcaaa gaacgcatct tgtgagccat gatagatgaa aaggcaaatt
    24121 tcagattctg catcttagtt ttcctccttt cctaactgag cactgtcaga cgaaatgacc
    24181 ccatcccgaa tgacaatctg acgtttggca taggcagcaa tctcaggctc atgcgttacc
    24241 atgataatgg tttttccttc tttattcaaa tcaaccaata attgcataat ttggttacct
    24301 gttttggtat ccaaggctcc tgtcggttca tccgctagga taatagaagg attgtttacc
    24361 aaggcacgcg caatggctac acgttgcttt tgaccaccag ataattctga aggtaaatgg
    24421 tgactacgtt ctgtcaattc aaccttgtct aaatattcct cagccaactt gcgacgtttt
    24481 gaagacgaaa ctcctgcgta aatcaagggc aattctacat tttgcagagc attgagcttc
    24541 gatagaagaa agaactgctg aaagacaaaa ccgatttgtt ggttacggac cttagccagt
    24601 tgtttttcac caagcccagc cacttcttga ccttcaagat aatattctcc actggttggt
    24661 gtatccaaca tgccaatcgt attcatcaga gtggacttac cagacccaga tggtcccatg
    24721 atggctacaa attcaccctc attcacttct agattgatat ttttgagaac ctgcaattct
    24781 tggtcaccat tacggtagct tctgaagata ttttttagac taattagttg cttcatcagc
    24841 cttcacctct tttccttctt ccaaggaaga tgttggatta ctgatgacct tagcaccgtt
    24901 cgttaaacca gaagtgattt cttgattttc tgcgtcagca tttcccaatg aaacctcaac
    24961 ttttttagcc ttttgttgtt catccacaat ccagacataa tttttactat catccattac
    25021 tagactgcta acaggaacaa gaatagcctt agttttgctt ttaacctcaa tgttgacaga
    25081 aaaaccttgt ttcaaatcac caacctcgcc tgtcacatca atagtataag ggtatttaga
    25141 acctgtatta ttcccggctg ctggactagc tgcttcacca ttgtttttag gatagtcaga
    25201 aatatagctt aatttcccag tccatttttt atcaggatac actttagaag taaagcttac
    25261 ttcttgacct acagaaaggt tggctagatt gtactcagac aattctccct tgacttgtaa
    25321 attttcattg ctgacaatat gaaccataac ttggctcgcc cctgttggag atttagaaac
    25381 attgctattg acttcgacta cagttccctc tagggtactg agaacagttg ttgcatccaa
    25441 ttgactttga gccttactta attgcgccgc agcatctgca cgcgcatcac gggcatcacc
    25501 caattgagcg tcaatagaag caacagaatt tccagccact ggagttgggc tttgcaccgt
    25561 tgcatcttct cctcctactg gcgctggtaa ctgtggagcc ggagctgaag cggcttcatt
    25621 tcgtgcttga ttgagttcat tgatatgacg atctgcctta gctactgctc gactagctga
    25681 atcataggcc gcctgcgctt ctgaactact gtacttgact aaagcctgcc cttcgctgac
    25741 cttatcgccc acagaaacaa ggatttcatc taaatcaccc ttactagcat caaaataaac
    25801 atattgttca ttttttgctg ttactgtccc tgacaataaa acagaggatg ccacgcttcc
    25861 ttccttggca acaacaagat gagtaggctc atcttttaga gcagtctgag aaggttgtct
    25921 aaagagtaaa atccccccgg cacccaatac aactacactc gcagcaccga ttgctgcata
    25981 cagttgccac tttttagctt taccattctt tttcttcata atgaaactcc ttttcttttt
    26041 tacaatactt tgctattata ccaaatttcc ctccagcaaa caatgcagtt cagatggaaa
    26101 taatggcagt tcaggattaa acaatcgttc ggaattttgc ttttctattg tactagatat
    26161 ataatacact atcttgactt atttggcaag cttttttgca attttttgtg cgtagcagat
    26221 ttttgcaatc aaatcaaaaa aagaataaaa tataactatc aaaaaagaca ctctactatt
    26281 taaaagatta caaaggagtt ttcaatgaga gaatatgata tcattgctat cggtggaggt
    26341 agcggaggaa tcgctaccat gaaccgtgct ggtgaacatg gagccaaagc agccgttatt
    26401 gaggaaaaga aattaggtgg aacctgtgtc aacgtcggtt gtgttcctaa aaaaatcatg
    26461 tggtacgggg cgcaaatcgc tgagactttc catcaatttg gagaagacta cggctttaag
    26521 actactgatc ttaactttaa ctttgcaacc ctacgtcgca atcgtgaagc ctacattgat
    26581 cgcgctcgtt cttcttatga tggtagtttt aaacgcaacg gtgtagactt gattgaaggt
    26641 catgctgaat ttgtagattc tcatactgta agcgtaaatg gtgaactgat tcgtgctaaa
    26701 catatcgtga ttgctacagg tgcccatcca agtattccta atattcctgg tgctgagcta
    26761 ggtggctctt ctgatgatgt atttgcctgg gaagaacttc cagagtcaat tgccattcta
    26821 ggcgctggtt atatcgccgt tgaattagct ggcgtactcc acacttttgg tgtcaagaca
    26881 gatctctttg ttcgccgcga tcgtccttta cgtggttttg attcctacat cgttgaaggt
    26941 ttggtcaagg aaatggaaag aacaaactta ccacttcaca ctcacaaagt ccctgtcaag
    27001 ttagaaaaaa ctactgacgg cattaccatt catttcgaag atggtactag tcacacagct
    27061 agccaagtta tctgggctac aggtcgccgt ccaaacgtta agggcttgca acttgaaaaa
    27121 gctggagtga ctctgaacga acgtggcttt atccaagtgg atgaatacca aaatactgtt
    27181 gttgagggaa tctatgctct aggtgatgta acgggcgaga aagaactgac tccagttgca
    27241 atcaaggccg gacgtaccct atctgaacgt ctctttaacg gaaaaactac tgcaaaaatg
    27301 gattactcaa ctattccaac tgttgtcttt tcacaccctg ctatcggaac tgttggtttg
    27361 acagaagagc aagctattaa agaatacggt caagaccaaa tcaaggttta taaatcaagc
    27421 tttgcatcta tgtactctgc ttgcactcgc aaccgtcaag aatcccgttt caaactcata
    27481 acagctggtt cagaagaaaa agttgtcgga cttcatggaa ttggctacgg cgttgatgaa
    27541 atgattcagg gatttgccgt tgctatcaaa atgggagcaa ccaaggctga ctttgatgca
    27601 actgtggcaa ttcacccaac tgcatctgaa gaatttgtaa ccatgcgtta atcgaaacaa
    27661 aagaagctga tataaatatg tctgcttctt ttttaatgat tttcgaatca acaaaaaaat
    27721 tatccaactt gactagtcac gaaaatcggc tgttacagtt tttgttacct tgtttttaaa
    27781 aaatggttga catcgactcc tatatgagta taatagttac tatacattag aaaagaggtt
    27841 aactattttg aaaaaagctc acgtttatgc tatccctgct attggggctg ctctcattgc
    27901 tgttttggca caaatcagtc ttccaattgg acctgttccc ttcactctgc aaaactttgc
    27961 aatcggcttg attgctactg tctttagacc gagagaggct gtactttctg ctggactcta
    28021 tcttcttcta ggtgctatcg gtcttcctgt ctttgcagga ggtggagctg gttttcaggc
    28081 tttagttggc cctactgcag gctatctttg gttttatctc gtttactctg gacttacttc
    28141 ctctctaacc aacagcaaga gtggtgttgt taagattttt cttgcaaacc tcttgggtga
    28201 tgcccttgtc tttgtcggcg ggattctcag cttgcatttc ctagctggaa tggcatttga
    28261 aaaagctctt gttgtggggg ttcttccctt tatcattcca gaccttggca aacttctggc
    28321 tattagtttt attagccgtc ccctacttca acgccttaaa aatcaggctt actttactaa
    28381 ctaaaaaagg ataccgagtt atcatgactc aatatccttt tttttatttt gaaaacttat
    28441 actcaatgaa aatcaaagag caaactagga agctagccgc aggctgctca aaacactgtt
    28501 ttgaggttgt agatgaaact gacgaagtca gtaaccatac ggcaaggcaa agctgatgcg
    28561 gtttgaagag attttcgaag agtattagtt gcctttaaag gcatccacca tcgtttgaaa
    28621 ttcttcattt gagagagtaa tccctttgcc cattttagta tggtctggac tccaagcacg
    28681 aatatcaaac tttgcagggg caccattaaa gctcacacgg ttaatttcct tggtccaacc
    28741 tttttcgttt tcagaaagag tcaacaagtg ctcttcgatt tcaaatgtaa attctgccat
    28801 tttcttctcc ttttttagtt tcattagttt attcgtaaaa tcttgtagat tttaggaaaa
    28861 ttttatataa tattgatata aaagaaggga ggccaatatg agacataaat tccagcaagt
    28921 tctagataaa atacatgatt ttttaaatgg acatgaccaa cctgaccaga ctgaaaccaa
    28981 ctcccttaca gccactattg aagaggctat ccagaaacaa accgctgttc accttatctt
    29041 gtctgagaca agctttacag gtgatatcat caaatatgat cagcaaggcc agcaaattat
    29101 cgtgaaaaat tttgccaaaa atgtgagccg gattatccgt ataagcgata ttcaacgcct
    29161 gcgatttgtc ccctcaactg tccaaacagc ccaaaaaaat agatttaaga aagagtgaga
    29221 tgtagttgct tcatcccact cttttttctt agcgaatttg ttcaaaatgt aaatgaactg
    29281 cgatatgatc tccataacca cttctttcca agtcacgttg taaacgatag gaaatgtagt
    29341 gttctgcaat ggtaatgtaa cctgcgccca ataaacgatg ttcaaccata gattgaatca
    29401 tactgatagt cgcacgttcc accttggctt cttgtaaatc caaaactacc ttcttagtga
    29461 cttgagcaag attttgacgc aaatcatctg tcaaaacata aacagtttgg gctgccttca
    29521 agatggcttg gtaaatctta tctggattaa attcagcaat ttcgccatta cgtttgatta
    29581 cttgcatagg tttctccttt attctttgtt ttctttgatt tctgccagca ttttttcttc
    29641 ttctactgtc agttgataat gttcaagtaa atccggtctg cgctcgtagg ttttctttaa
    29701 actctcgtac aatcgccact gacgaatctt ttcatggtgg ccactcatca atacatctgg
    29761 cacgaccatg cctcgataat catagggacg tgtgtactga ggatattcta aaagacctga
    29821 agaaaaacta tcatcttggt ggctagactc cttgccaatc acttctggaa tcaggcgaac
    29881 tgtagcatca atcatggtca tagctgccaa ttctccacca gtgaggacat agtcgcctag
    29941 ggaaatctca tctgttacca aggtcttaat gcgctcatca taaccctcat agtgcccaca
    30001 gataaagatt agctcttcct cttgagccaa atcttcagca taagcctgat caaactgctt
    30061 tccagcagga tcgaggagaa taacgcgcgg atttttcttt tcaatagcat caaaggaatc
    30121 gaaaataggt tgtgctctga gcaacatgcc ctgaccgcct ccgtagggct catcatctac
    30181 atgacgggcc ttttcagcat tttctcgaaa attatgatac tggatatcca agagcccttt
    30241 ttctcgagcc tttccaacga ttgagtgctc cagtggagaa aacatctctg gaaagagggt
    30301 taaaatatca atcttcatcg tctaaccctt ctaagatttc cacatcgacc cgtttatttg
    30361 gaatatcaac attgagaacc actggtggga tataaggtaa aagcaaatca cgtttgcctt
    30421 ttcgtttgac cacccagaca tcattagcac ctggttgcag gatttccttg atggttccaa
    30481 ccaagctatc accctcatag acttccaaac cgataatctc gtgatagtaa aattcaccat
    30541 cgtctaggtc attcaaatct tcctcagcga ccttgagact gtatcccttg tacttttcga
    30601 tagtattgat atggtacata tctttgaatt taataatgtc aaagttcttc tgtttacggt
    30661 ggctagcgat ggtcactgtt tggacaaact gatctttttc atcaaacaaa gtcagctcag
    30721 ctcctttttt aaaccgttct tctgcaaaat ccgtcacaga caatactcgc atctcaccct
    30781 gtaatccctg cgtattaacg attttcccaa cattaaagta gttcatcttg tctcctgtaa
    30841 tctccttttt ccatcttatt ctgacaattc tcgaataata gccgcaattt tttccgattc
    30901 tgaccattgt aaataatggt gattccttcc taaaatgagt ttagtattgg aagtccaata
    30961 ttctgattct ctgtactctt tttctctata agtctgacaa aaaataaata cagggacatg
    31021 agattctatc gacaaattct caaaatcttc ctcagtaatc tctccagata tctgaaattc
    31081 tggatcttga ttttccaact ctaagccttt ttcttgcatt aattcccaga tttttttatt
    31141 cgtttcagga ctaaatgttg cttgagttaa gttcttaaaa taaagttcag gaccacactc
    31201 gtcaatcagc ctcatctgct cttccatttc tggataagga ttttctgaaa aatcagcaaa
    31261 catgactttt ttagttgtcg gttcaattgc tactaaagtc tgacacttaa ttggtttctc
    31321 gagtaatttg caagctaaaa ttccactcca actatgtgca caaagtatat attcagaaat
    31381 tcctaattct tcaagtactt cataaaccgc atctgcaaga ttatctagat tttttccagc
    31441 ttggtcatga atcggactcc tacctgtgtt cggaaaatca attgtcaaat aaccaattgt
    31501 aggaggaggt ttttcaagta taagtgaaaa attttcataa cttggtagca aacctgctcc
    31561 gtttagacaa actagcactt tcttttgctt tttataagta acagagaggc taccaatttc
    31621 tgtagatact tcaaacctct tcataaagaa atccactcat tctatataat gaattattaa
    31681 aaatccttat cctttatttt atcacgttcc aaagattttc tcaagttgga ggaaggggac
    31741 aatatctcta ctttcccttc aagaatcctt ccaaatcatg tttatgttgg taattaacgg
    31801 ctgcggtttt gtctttctca aagatggttc tagttaggtc aatatgcttg atagcagcaa
    31861 tagcgacggt gtagtgaatg atattagcca gttctatggc aggttcctcg ttcgaatcct
    31921 atcccttctt ttcgaccaga gcgcctattc aaaacctcgg ctacttctcc gacttcctcc
    31981 actaacttca taaagagacc ttcatcagtc cgagactgct gttaatgttc gagtaagtag
    32041 tcttggaatt gcctaaacgt tcaatctttt atagtatatt gaaactagaa tagtacacct
    32101 ttacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttg tcctgttatt
    32161 atttcatttt actatatctt ctattccaca caaaaaagcg agacatccgt cccgcccttc
    32221 ttatttttcg tcaataacga ttcttacttt tttgtattca gttgggacag agtagacaat
    32281 cgttcttatc gcagaaatag tgcgaccctt acgaccgatt acacgaccca catcgctttg
    32341 atcaagattc aaatgatatt ccaaaaattc tggtgtatcc tcaatcttga tagttaaggc
    32401 atctggttgt gaaattaagg gtttcacaat cgcaataatg agattttcaa tcgtatccat
    32461 ctgtcaacct actttaaact tattttgaga atttagaatc gtggaatttt ttcaatacgc
    32521 cttcttttga aaggatgtta cgtactgtgt ctgaaggttg agctccatta gccaaccatg
    32581 caagaacgcg gtcttctttc aaagttactt ggttttcagc aacaagtggg ttgtaagttc
    32641 caactgtttc gatgaaacgt ccgtcacgtg gtgaacgtga atctgctacg ttgatacggt
    32701 agaaaggttt tttcttagaa cccatacgag tcaaacggat tttaactgcc atttttaaag
    32761 tctcatttct ttaatttttt atttcggtga aatagctgag ctatttagca catgttctat
    32821 tatagcagat ttctggcagg tgtcaagaaa aaaacttgac agactataaa tttcttaaag
    32881 catttagaaa tttgttagaa taggaaataa atgtttgaaa gatgctatcc gtgaatacta
    32941 ttttagaaaa attttataaa gaacaccaag tcaaaccctt catatcgcct gaacgagatt
    33001 tggatacttg gcttctaagt cccaaacccg ttcccaagcg aaatatggac ttattagcag
    33061 atgattcact agcaggagat atcattttac tatggagaat ccagtttggt acttttacca
    33121 ctgaaacatg attttaaaaa ctcccattcg aatatgattc aaaattcgct tagaatcaat
    33181 gttttcccac tttttcaaaa aataaatttt catctaattt aaataacttt caattaagtg
    33241 tgaattttgc ttaaaatcat taaaaaacac cccatggtgt gaaccatgaa gtgttgtaaa
    33301 tgctgtgttg tagctagttc ttagcgttta gagaactggc tagctttacg agctttctta
    33361 agatctggtt ccctaaatac tttgagtaca cttatggcat tgatgcccca aaacatctaa
    33421 aaactctggt agaaaaaggg tatgctcttg tcgaaacttc ttttgactca cttgaccatc
    33481 taaataatac catgaaaaag aatatcctga agaagaagaa gggagttact ggactttcta
    33541 aaatgaaatc ttgcgacctg gatcaagccc ttcatgagca tttttcagaa gaagaattag
    33601 ctggtcactt tcatgtcctt ctatggactt ttttacaatg gcattgctat cacacccaat
    33661 acctatctaa gcgcctggtt cgtaaacttt attgcagctc ttcctctaaa tttcctaatt
    33721 gttgaaccaa ttgcccgttt tatactaagt tcttttcaga aaccatttac tggggaagaa
    33781 gttgaagatt ttcaagatga tgatgaaatc ccaactatta tctaagccag ttctgtaaac
    33841 tactaatatt tgaaatccac ttccttttag ggtacaatgg ttataaatga atttttgaga
    33901 ggatcagaat gaaaaaacta gcaacccttc ttttactgtc tactgtagcc ctagctgggt
    33961 gtagcagcgt ccaacgcagt ctgcgtggtg atgattatgt tgattccagt cttgctgctg
    34021 aagaaagttc caaagtagct gcccaatctg ccaaggagtt aaacgatgct ttaacaaacg
    34081 aaaacgccaa tttcccacaa ctatctaagg aagttgctga agatgaagcc gaagtgattc
    34141 tccacacaag ccaaggtgat attcgcatta aactcttccc taaactcgct cctctagcgg
    34201 ttgaaaattt cctcactcac gccaaagaag gctactataa cggtattacc ttccaccgtg
    34261 tcatcgatgg ctttatggtc caaactggag atccaaaagg gaacggtaca ggtggtcagt
    34321 ccatctggca tgacaaggat aagactaaag acaaaggaac tggtttcaag aacgagatta
    34381 ctccttattt gtataacatc cgtggtgctc ttgctatggc taatactggt caaccaaaca
    34441 ccaatggcag ccagttcttc atcaaccaaa actctacaga tacctcttct aaactcccta
    34501 caagcaagta tccacagaaa attatcgaag cctacaaaga aggtggaaac cctagtctag
    34561 atggcaaaca cccagtcttt ggtcaagtga ttgacggtat ggatgttgtg gataagattg
    34621 ctaaggccga aaaagatgaa aaagacaagc caactactgc tatcacaatc gacagcatcg
    34681 aagtggtgaa agactacgat tttaaatctt aaaaaccaaa aaaatacagt atccacattc
    34741 ggtactgtat ttcttttact ctcattctta agttaaatta ttaaaatccc atatttggtc
    34801 tatccagcct tcataaaagt ctggctcgtg gcagaccata aggatagatc ccctatattc
    34861 tttgagagcg cgtttgagct catcctttgc atccacatcc aaatggttgg tcggctcgtc
    34921 cagcactaaa acgttgtttt cacgattcat caagagacag aaacgaacct tggcttgctc
    34981 tccccctgat aatacttgaa tctggctttc aatatgtttg gttgtcaaac cacaacgggc
    35041 aagggctgca cggacttctg cttgattaag ggcaggaaag gcattccaga cagcttcaag
    35101 aggagtttgg cgattaccgc cttctacttc ctgctcaaaa taaccaagtt ctaaataatc
    35161 tccacgctcc acttccccag cgattggcga gataatgcct aagagactct tcaagagagt
    35221 tgtttttcca ataccattag caccaataat cgcaaccttt tgattgcgtt cgaaggtaag
    35281 atttaaaggc ttagtaagag gacggtcgta accaatttgc aagttcttgg cttggaagat
    35341 aaagcgccct ggtgtacgag ctggtttgaa atcaaaggat ggttttggtt tctcactttg
    35401 gagttcgata atatccatct tatccaattt cttttgacga gacatagcca tattacgagt
    35461 tgcaacacgg gctttattac gagccacaaa gtccttgagg tctgcaatct ctttctgctg
    35521 gcgttcgtag gctgcctcta gctgagattt cttcatagca taaacttctt ggaactggta
    35581 gtagtcacca gagtaacgcg tcagctgttg attttccaca tgatagacaa tattaataac
    35641 gtcattgagg aatggaatat cgtgcgaaat gagaacaaag gcattctcat agttttggag
    35701 atagcgcttg agccaatcaa tatgctcagc atccaagtag ttggtcggct cgtccaacag
    35761 caagatatca ggcttttcaa ggagaagttt tgccaaaagc accttggttc tttgcccacc
    35821 tgacaaagaa gttacatccg tatccatgcc aaagtccata acaccaagag cacgcgctac
    35881 ttcgtcaatc ttagcatcca aggtatagaa atcacgactc tccagacggt cttgaagttc
    35941 tcctacttct tccatgagag catcaacatc cgcgccgtct tcagccattt tcatatagag
    36001 gtcattgata cgagcttcag ctttaaaaag ctcatcaaaa gccgtacgga gaacatcacg
    36061 caccgactgt ctttcagcaa ggacagagtg ctgatccaag taaccagccg tcacatattt
    36121 ggaccactca acctttcctt catctggcag cattttacca gtcacgatac tcataaaggt
    36181 tgattttcct tcaccattgg caccgaccag gccgatatgt tctcccttga ggagacggaa
    36241 ggacacatct tcaaaaattg cacggtcacc aaaaccgtga ctcagatttt taacttctaa
    36301 aatactcatt ttaattcctt atcttgtttt tatgtaatcg tttataaagg agccaagcca
    36361 gatagccacc caaagtgttg gtccacaaat catcaatctc aaagacgcga ttgaaatcaa
    36421 agaaaaagtc caagattaat tgcgtacact cgattccaag actcacaaga aaactaaaaa
    36481 gaaggacctt ttttgttttc cgcaaatttg gaaatagata aaggagttgg aaaatcagag
    36541 gaaaaaacaa gaagacattg aggacatttt gtaaaaaaat ccaacataat tgtccaatgt
    36601 cactcacttc gcccagtttc cagagagaat tgaaaggagt caaaagaaaa accaggcgtc
    36661 caagatgctg aatacctgga gttcccactc ccacggtaga ttgttcttga ggagtaaagc
    36721 aaaaacagac aatgcaaatg ctatagaaaa tgactcccca gaccaaaata tgattataag
    36781 tcttcttcat cattaaggat ttaccgctgc gactgccttc tggcggtcac gtttcattgt
    36841 gttagagcgc aattgtccac aagctgcgtc aatatctgta ccatgctctt gacgaaccac
    36901 acagttgacc ccttttttct taagcgtatc atagaaagcc aacacgcgct ctttgggact
    36961 acggctatat tggtcatgct cactaactgg gttataagga atcaagttta cataagacaa
    37021 tttcttgatg ttcttgagca attcagtcaa ttccaaggct tgttctacac tgtcgttgac
    37081 ttcattaagc atgatatatt caaaggttac acgacggttt gttgtctcaa tgtagtattc
    37141 aatagcagca aagagttttt caatcggaaa ggcacggtta atcttcatga tacttgaacg
    37201 aagttcattg ttaggtgcgt gaagagacac ggcaagattg acctgaaccc cttcatcagc
    37261 aaagtcacga attttatgag ccaaacctaa ggttgaaacc gtgatgtgac gagcaccgat
    37321 agtcattcct ttatcatcat tgatagtacg aaagaaattc aagacattgt tgtaattatc
    37381 aaagggctca ccgattccca tgacaacgat atggctgacg cgttcatcct gaccacgctc
    37441 atcaaagtat ttctgaacca gcatgatttg cgctacgatt tcaccgttat tgaggtcacg
    37501 ttgcttctta atcaaaccag aggcacagaa ggtacaaccg atattacagc cgacctgagt
    37561 ggtcacacag acagataaac catagtgttg acgcatgagt acagtctcaa ttaacatacc
    37621 gtcgggcaat tcaaagagat atttgactgt accatcagca gactcttgca caatacgttg
    37681 tttcaaggga ttgaccacaa actggtcatt gagcttagca atcaaatcct tggaaaggtt
    37741 ggtcatttct tcaaatgact gcacacgttt acggtagagc cattcccaga tttgatctgc
    37801 acggaatttc ttttctccct gctccaatac ccattcctgc atggtttgat gtgccaaact
    37861 atgaattgag ggtttcattt cttctcctta ttctctactc acttctgacg aatgacaaaa
    37921 tgacgttgtc ccttgtcctc tttctgagaa tgctggtctt tctgacgacg tctattcttc
    37981 ttatctgcat tcgactttcg tttagtttga gtcggtttct ttccttttct agaaggtgtt
    38041 tcttcttccg tcttacgcat tttcttgtca aatgatgctc gcttaggggc ttcattttct
    38101 aagacaaaat aggcacaacc ataactacaa tactctaaaa ggtagtcttg taaacgactg
    38161 attttttcaa gtttttcttc tgttcggtca tccttgtaaa aacctcgtag gcgaagctgt
    38221 tcgttgctcc agtcccccac gatataatca aacttggtta atacttctga aaaacgctga
    38281 ttaaaagtcg tcacatcaaa ggcatccttg atattttcaa ccaaggaaaa agctatccct
    38341 tccgtttcga ccttgtcccc gtgtaaatgg aactccggac caggaaactt gttatagttg
    38401 tataattcag gtgcaatttc ttttcgcata gatatccttt ttccacgatt acttaatact
    38461 ttattctacc ataatttcta gcagttagca cgtttctcat aaaaatgaaa aaagtctgac
    38521 gattttgtca gaccagaatc ttataaccta aaaagagaag aacaattctt ccctccaact
    38581 atcattattt agcagctgcg tacaattcat ctactttatt ccagttgatt actgaaaaga
    38641 aagctttgat gtagtcagga cgcacgttgc ggtatttcac gtagtaagca tgttcccaaa
    38701 cgtccaagcc caagattggt tttttacctt ctgagattgg tgtgtcttgg tttgctgttg
    38761 aagtcacttc aagtttccct tctttgttga caaccaacca tgcccaacct gaaccaaaac
    38821 gagttgttgc tgctgcagtg aaggctgctt ggaattcttc aaatgaacca aatgttgcat
    38881 cgattgctgc tgccagttct gctgaaggag ctgttttctc gggagtcatc aattcccaga
    38941 aaagagcgtg gttcaagtgt ccgccaccat tgttgataag tgcttgacgg atatcagctg
    39001 ggatagattc tacatcagca agcaaggctt caaggtcttc accgatttca gggtgttttt
    39061 ctaaagctgc attggcattg ttgacataag tttgatggtg tttgtcatgg tgcaaatgca
    39121 ttgtttccgc atcgatgtat ggttccaaag cgtcgtatgc atatggaagt tctggtaaga
    39181 taatagccat ctgtaatacc tctttttctt tctatatgaa aatgataacg caaacattca
    39241 cttttttcaa gttttttgct tatagataag gaaatcactg acatactttc taataaaata
    39301 agcaaatcag caagaaaccc acgacaagat aatcctgacg cgggttgtag tttcaacaaa
    39361 tgtcaattga cctgactagc aatctgtaag agtgcctttt caaaaaggaa acctttttca
    39421 taaagacctg tcttaatctg atagtctgtc tcaatcaaat aggaaatagc ttgcttcaga
    39481 aagctcaaag aaagtcctct cgaatctctt aatgcaaact tgatttgata aggatttggg
    39541 ttacgtccca gataactacc taaactactt gcaatctgcg attctgtttg gccagactcc
    39601 gccaaaatct tcacctgagt aaaagtccga aattgtccca gcatgactgc aatcagtttg
    39661 atttcatctt ccccttgcaa ggtcaagtct ctcaccaaat cgcgcgcctg atccatcttt
    39721 ttagtcagaa taaactgagt taaatcaaaa atattgtcct gcaaggtctt gggaattgcg
    39781 ttaacaatat cctcttcctc gataacagaa tccgccttat aggactgtaa aaagagaaga
    39841 tttttctgga tttcgctaaa ttgaaacccc gacttgatga ggagattttc aaaagaatga
    39901 ttggtaaact gcagaccttg tttctgactc cacttttgga aatactggcg caattcttgt
    39961 tcttttactt ctactgcatc gaagaccttg gcatcacgct taagtaattt gactaaccgt
    40021 cttttgctat ccagctttcc ttctgcaaag attatcaact tggttgttgg agaaggattg
    40081 tcaaggtatt cctcaaatga cttaagctca tcatctgtca aaaagcgttt cttagcagtc
    40141 gtgatatcca taaaataatc taatatcacg attttctcat ccgcaaagaa aggaaggctg
    40201 accaactcca gttccacatc cttgtaaact acttctttca tatcaaagta ggcaaagttg
    40261 aggtcagcag aatcataccc aatctgtttc aacacttgac tcttcatcac ttcaaactga
    40321 ccctgatctg tccctgtaaa taggctcagg ctcggtaaat ttgataaagt caacttctga
    40381 ctttcttcaa tggctagcat cgtctctcct ttcttcagat ttttcgattt aatttagtca
    40441 atatagcgca atttcccacg gaaatcttct aagctctcgt agcctttttc caccatgatt
    40501 gctttcagtt cattggtaat gcggtcaaaa gcactgacgc cttctttgtg aagggtcgtt
    40561 cccacctgca ccatacttgc tccacagagg atgtgttcaa aggcatctcg accagtcaga
    40621 acgccacctg ttccgataat ttggatttga ggatttaaac gttgataaaa ggcgtgaaca
    40681 ttggctagag cagtcggttt gatgtattct ccaccaattc caccaaaacc attcttaggc
    40741 cgaataacga cagattcgtc ttctatatag aggccgtttc cgatagagtt aacgcagttg
    40801 acaaacttga gcggatattt gttgaaaata gctgccgctt gatcaaagtg aacaatatca
    40861 aaataaggtg gcaatttaat tccaagaggt ttggtgaagt aagcaaacac ttctgccaaa
    40921 atccggtctg ttgtctcaaa atcataggca atctgaggtt tacctggaac atttggacag
    40981 gaaagattta gctcagtcag accacgaaaa tcactctctt ggactttttt caaaatagta
    41041 tgggtttcct ctggagacat gccgaccaga gataagaaga aagttcggtt cgactctttt
    41101 tcctgcaaat ctaaaagata atccaaataa tagtctaagc cattatttgg caagcccata
    41161 gagttgatgg aaccaagtgg aacatcttgg tagcgtggct caggattccc ctgacggaag
    41221 tccaaggtcg ctgtcttagt aacaaaggtt cctgccgctg agtttttgac ctcttctaac
    41281 tcctctatcg tcatacaagc cacacctgct gcattcatca agcaattgtc aaactcaaaa
    41341 ccagcaattt gtgttttcgt tgataccatg attctaatcc tccagatttc ttttattgct
    41401 aatattatac cataatttta attctaggtt tactagattc tgtggttcta tctatttatt
    41461 cggaaaagaa agtctagtac agaagtcatg ctatggaaac agctagtgta ttagaagttt
    41521 gaacaaggct tgggtaacag acttttgaat gaagtccaag caacaaggag aaatctcaac
    41581 catgagtcca ttccatgact ctgttgctct agaaaacctt gcaatagtca agtgataacg
    41641 aataaaactt tggattgaaa tatccccaag attatctatt acgaggagaa atcttaacct
    41701 ttatcatttt taaagaaata tagtaaaatg aaacaagaac aggagaaatc gatcaggaca
    41761 gtcaaattga ttgctaacaa tgttttagaa gttgaggtgt actattctag tttcaatcta
    41821 ctatacatgt aaatctctac tttcgcaaaa tggattttca gaacagtatc ccagtatagt
    41881 taaaaactat aaaaaagaga ggacgttccc ctcttaaaat cttattttac tgcttctttc
    41941 aaagcatcta ccttatccaa acgttcccat ggaagatcaa tatctgtacg tcccatgtga
    42001 ccgtaagccg atgtttgacg gtaaattgga cgcttgaggt ccagcatttg gataatccct
    42061 gcagggcgaa ggtcaaagat ttgacgagcc gctttttcaa gttgactttc agctactgtt
    42121 cctgtaccga aagtatcgat acgaacagaa acaggttgcg caacaccgat agcataggcc
    42181 aactgcactt ctgccttctt agcaaggcct gctgcaacga tattcttggc aatatagcga
    42241 gccgcataag aggctgaacg atccacctta gtcgcatctt taccagagaa ggcaccacca
    42301 ccatgacgag agtagccacc ataagtatct acaataatct tacgaccagt caaacctgag
    42361 tccccttgag gaccaccgat tacaaaacga cctgtcggat tgataaagaa ttttgtctta
    42421 tcatcaagat aagaagatgg aataacttct ttgatgacct tgtcaatcac atcttgatgg
    42481 atttgttcat tagtggcctc tggatcatgc tgagtagaaa taacgactgt atctacacgt
    42541 accggacggt cattttcatc gtactcaact gtaacttgtg attttgcatc tggacggaga
    42601 tagctaattt ctccagactt acgaagttct gccagacgac gaaccaattt atgactgagt
    42661 gcaattggca atggcataag ctcttctgtt tcatctactg caaatccaaa catgagccct
    42721 tggtcacctg ctccaatcaa gtccagtgga tcttgatcag catttccacg aacctccaag
    42781 gcttcgttaa caccttgagc gatgtcagga gattgttcca ccaaagatgg gtgtactccc
    42841 accgtctcag cagaaaatcc atattctgta ttggtataac caatctctgc aatggtatca
    42901 cgaaccacac ggttaatatc cacataggca tttgtagaaa tttcaccaaa aacgtggaca
    42961 gaaccagtat atacagctgt ttcagcagca acgtgcgcct ctggatcctt tgctaaaata
    43021 gcatccaaaa tcgcatctga aatttggtct gcaatcttat ccggatgccc ctcagataca
    43081 gattcagacg tgaataattt acgttctgac ataaaaatgt ccccccttaa aaaatattgt
    43141 tatagagtta caaagtactg ataggaaaac tcttcgtaat aaatacctac catcttatcg
    43201 ggactatata actttatcat tataccattt ttaatcgcaa tttgcagtct ttaatgtagt
    43261 gtttcggttt agatagttcg ttctcataaa gcaaaaagtt ggagctcagt actccaacaa
    43321 tttctattaa aatgtttgac gtttagcttt acgctctgca cgaccgcgag cgcgattttc
    43381 agcacgcttg gttttacggc gcttttcatc aaccgcccat tgaattttct tcttataacc
    43441 cggtttgact tttttctttt tctttttaac caaaccaatc atttcgatat caagtttatc
    43501 ttgttttttc tcacggttgg cacgacgatc acggtcatag gtatcttgaa attccccgtc
    43561 tttgaccatc ttaggactaa acttgattcc caatttctcc aactcacgga tatccgagtc
    43621 atcacttggc tgataaaggg taatagctgt acctggtagg ccatttcgtc cagtacgacc
    43681 aacacggtga acaaaaaaag ataagtcttg cggaatggca tcattgatga catggctgac
    43741 accttcaatg tcaatcccac gtgctgccaa atctgttgcg acaatatact caaaatccag
    43801 attttgcacc tgattcatga ttcgcttgcg ttcacgaggg gcaatatcgc catggatttt
    43861 tgcaaccttc aagccttgag cagtcagata tgaatgcaat tcatcagcac gcgttttagt
    43921 gttaacaaaa atcattgcca aatacggctg catcaactga gtcaactggt aaatttgagc
    43981 attcttatca tgtcccttgg tcgaaatcaa ccaattatca atggtgtcag aaataaccgt
    44041 tttggtctta attttctcca taacaggatt ggataagtat tttttcaaga atggttgcag
    44101 tttttgtggg atagtcgctg agaagaccat gaattgcaag tcttttggaa gactgccagc
    44161 aatcttatca acagtttcca agaatcccat atccaaggtc atatccgctt catcaacaac
    44221 aaatgtcttg gctttatgaa tagctaaatc accagattta accaagtcgt agatacggcc
    44281 tggtgttcca ataacaatat gaggctgatt gcttgccaat ttctcaatct ggcgagcctt
    44341 atccgtacca cccacataat taaccacacg aacttcgaca tctgagtgag ctgaaatctg
    44401 acgcgctact tggtaaattt gagtagccaa ctcacgactc ggtgcagtaa tcactgcttg
    44461 tacactatcg ctagcttcat ctaattgctg gaaaatcggt aacaagaaag tatgagtctt
    44521 acctgaacct gtttttgatt ctcctactag gtcacgacct gccaaaacaa taggaatcaa
    44581 cttgtcttgc acctctgttg gagttgtaaa ttttaactcc tccaaggctt ctctaatata
    44641 gtttttaaat tgaaatttcg taaatgacat aacatcctcg attctatcta tcttatcaat
    44701 tataccatat tttattccat tacagtagtc tcacttattt aggctatttc cagtagcttc
    44761 tctagtaaga aaaggctgga attttatacc ccaattattc acccctaatc taaaaa
//
LOCUS       DBEJKC010000010        44577 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.010, whole genome shotgun sequence.
ACCESSION   DBEJKC010000010 DBEJKC010000000
VERSION     DBEJKC010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 44577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44577
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.010"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(115..330)
                     /locus_tag="ACL3G6_000552"
     CDS             complement(115..330)
                     /locus_tag="ACL3G6_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545132.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(1201..2451)
                     /gene="ilvA"
                     /locus_tag="ACL3G6_000553"
     CDS             complement(1201..2451)
                     /gene="ilvA"
                     /locus_tag="ACL3G6_000553"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HGR0545133.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(2501..2857)
                     /locus_tag="ACL3G6_000554"
     CDS             complement(2501..2857)
                     /locus_tag="ACL3G6_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGR0545134.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(3095..3331)
                     /locus_tag="ACL3G6_000555"
     CDS             complement(3095..3331)
                     /locus_tag="ACL3G6_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545135.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(3438..4460)
                     /gene="ilvC"
                     /locus_tag="ACL3G6_000556"
     CDS             complement(3438..4460)
                     /gene="ilvC"
                     /locus_tag="ACL3G6_000556"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGR0545136.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGSRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(4526..5002)
                     /gene="ilvN"
                     /locus_tag="ACL3G6_000557"
     CDS             complement(4526..5002)
                     /gene="ilvN"
                     /locus_tag="ACL3G6_000557"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HGR0545137.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(4995..6695)
                     /locus_tag="ACL3G6_000558"
     CDS             complement(4995..6695)
                     /locus_tag="ACL3G6_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HGR0545138.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(6896..8563)
                     /locus_tag="ACL3G6_000559"
     CDS             complement(6896..8563)
                     /locus_tag="ACL3G6_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HGR0545139.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(8566..8931)
                     /locus_tag="ACL3G6_000560"
     CDS             complement(8566..8931)
                     /locus_tag="ACL3G6_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR0545140.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(9088..9276)
                     /gene="rpmB"
                     /locus_tag="ACL3G6_000561"
     CDS             complement(9088..9276)
                     /gene="rpmB"
                     /locus_tag="ACL3G6_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HGR0545141.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(9392..9628)
                     /locus_tag="ACL3G6_000562"
     CDS             complement(9392..9628)
                     /locus_tag="ACL3G6_000562"
                     /inference="COORDINATES: protein motif:HMM:NF013652.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR0545142.1"
                     /translation="MCGFFRYFIPKYVSESRVLYLDLDIVVRKSIDELWDLDLTAIPL
                     AAVRDDFYTHNFNSGVLLINNGMWRAENVTQDLI"
     gene            complement(9779..9877)
                     /locus_tag="ACL3G6_000563"
     CDS             complement(9779..9877)
                     /locus_tag="ACL3G6_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HGR0545143.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHLL"
     gene            complement(10305..11849)
                     /locus_tag="ACL3G6_000564"
     CDS             complement(10305..11849)
                     /locus_tag="ACL3G6_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HGR0545144.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNKRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            12062..12364
                     /gene="gatC"
                     /locus_tag="ACL3G6_000565"
     CDS             12062..12364
                     /gene="gatC"
                     /locus_tag="ACL3G6_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HGR0545145.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            12364..13830
                     /gene="gatA"
                     /locus_tag="ACL3G6_000566"
     CDS             12364..13830
                     /gene="gatA"
                     /locus_tag="ACL3G6_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HGR0545146.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQTTLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLSAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            13830..15272
                     /gene="gatB"
                     /locus_tag="ACL3G6_000567"
     CDS             13830..15272
                     /gene="gatB"
                     /locus_tag="ACL3G6_000567"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HGR0545147.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNTEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            15401..15961
                     /gene="efp"
                     /locus_tag="ACL3G6_000568"
     CDS             15401..15961
                     /gene="efp"
                     /locus_tag="ACL3G6_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HGR0545148.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            15983..16372
                     /locus_tag="ACL3G6_000569"
     CDS             15983..16372
                     /locus_tag="ACL3G6_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR0545149.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            16365..16787
                     /gene="nusB"
                     /locus_tag="ACL3G6_000570"
     CDS             16365..16787
                     /gene="nusB"
                     /locus_tag="ACL3G6_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HGR0545150.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQMVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(16837..17073)
                     /locus_tag="ACL3G6_000571"
     CDS             complement(16837..17073)
                     /locus_tag="ACL3G6_000571"
                     /EC_number="3.4.26.-"
                     /inference="COORDINATES: protein motif:HMM:NF014566.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HGR0545151.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(17086..17559)
                     /locus_tag="ACL3G6_000572"
     CDS             complement(17086..17559)
                     /locus_tag="ACL3G6_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545152.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(17577..17762)
                     /gene="briC"
                     /locus_tag="ACL3G6_000573"
     CDS             complement(17577..17762)
                     /gene="briC"
                     /locus_tag="ACL3G6_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HGR0545153.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(17921..18688)
                     /locus_tag="ACL3G6_000574"
     CDS             complement(17921..18688)
                     /locus_tag="ACL3G6_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HGR0545154.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(18685..19551)
                     /gene="accD"
                     /locus_tag="ACL3G6_000575"
     CDS             complement(18685..19551)
                     /gene="accD"
                     /locus_tag="ACL3G6_000575"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HGR0545155.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(19588..20955)
                     /gene="accC"
                     /locus_tag="ACL3G6_000576"
     CDS             complement(19588..20955)
                     /gene="accC"
                     /locus_tag="ACL3G6_000576"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HGR0545156.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVKKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(20967..21389)
                     /gene="fabZ"
                     /locus_tag="ACL3G6_000577"
     CDS             complement(20967..21389)
                     /gene="fabZ"
                     /locus_tag="ACL3G6_000577"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0019171 -
                     (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HGR0545157.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(21386..21871)
                     /gene="accB"
                     /locus_tag="ACL3G6_000578"
     CDS             complement(21386..21871)
                     /gene="accB"
                     /locus_tag="ACL3G6_000578"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HGR0545158.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(21874..23109)
                     /gene="fabF"
                     /locus_tag="ACL3G6_000579"
     CDS             complement(21874..23109)
                     /gene="fabF"
                     /locus_tag="ACL3G6_000579"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HGR0545159.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(23131..23862)
                     /gene="fabG"
                     /locus_tag="ACL3G6_000580"
     CDS             complement(23131..23862)
                     /gene="fabG"
                     /locus_tag="ACL3G6_000580"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HGR0545160.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(23896..24816)
                     /gene="fabD"
                     /locus_tag="ACL3G6_000581"
     CDS             complement(23896..24816)
                     /gene="fabD"
                     /locus_tag="ACL3G6_000581"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HGR0545161.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(24809..25783)
                     /gene="fabK"
                     /locus_tag="ACL3G6_000582"
     CDS             complement(24809..25783)
                     /gene="fabK"
                     /locus_tag="ACL3G6_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HGR0545162.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(25903..26127)
                     /locus_tag="ACL3G6_000583"
     CDS             complement(25903..26127)
                     /locus_tag="ACL3G6_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGR0545163.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(26187..27161)
                     /locus_tag="ACL3G6_000584"
     CDS             complement(26187..27161)
                     /locus_tag="ACL3G6_000584"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HGR0545164.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(27161..27595)
                     /locus_tag="ACL3G6_000585"
     CDS             complement(27161..27595)
                     /locus_tag="ACL3G6_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGR0545165.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(27689..28474)
                     /locus_tag="ACL3G6_000586"
     CDS             complement(27689..28474)
                     /locus_tag="ACL3G6_000586"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HGR0545166.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            28844..30208
                     /locus_tag="ACL3G6_000587"
     CDS             28844..30208
                     /locus_tag="ACL3G6_000587"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HGR0545167.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREIGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYYAFFGE
                     SKED"
     gene            30211..30582
                     /locus_tag="ACL3G6_000588"
     CDS             30211..30582
                     /locus_tag="ACL3G6_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HGR0545168.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKVSRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            30796..32070
                     /gene="serS"
                     /locus_tag="ACL3G6_000589"
     CDS             30796..32070
                     /gene="serS"
                     /locus_tag="ACL3G6_000589"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HGR0545169.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(32095..32994)
                     /locus_tag="ACL3G6_000590"
     CDS             complement(32095..32994)
                     /locus_tag="ACL3G6_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HGR0545170.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(33104..33652)
                     /locus_tag="ACL3G6_000591"
     CDS             complement(33104..33652)
                     /locus_tag="ACL3G6_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HGR0545171.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(33870..35186)
                     /locus_tag="ACL3G6_000592"
     CDS             complement(33870..35186)
                     /locus_tag="ACL3G6_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HGR0545172.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALTQS
                     AFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLMVL
                     LGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFNK"
     regulatory      complement(35277..35365)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(35529..37865)
                     /locus_tag="ACL3G6_000593"
     CDS             complement(35529..37865)
                     /locus_tag="ACL3G6_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HGR0545173.1"
                     /translation="MNKKILETLELDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLTSREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKVKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYVEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(37969..38517)
                     /locus_tag="ACL3G6_000594"
     CDS             complement(37969..38517)
                     /locus_tag="ACL3G6_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HGR0545174.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(38514..38816)
                     /gene="zapA"
                     /locus_tag="ACL3G6_000595"
     CDS             complement(38514..38816)
                     /gene="zapA"
                     /locus_tag="ACL3G6_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HGR0545175.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            38903..39784
                     /gene="rnhC"
                     /locus_tag="ACL3G6_000596"
     CDS             38903..39784
                     /gene="rnhC"
                     /locus_tag="ACL3G6_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HGR0545176.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFDYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKKRLER"
     gene            39788..40402
                     /gene="lepB"
                     /locus_tag="ACL3G6_000597"
     CDS             39788..40402
                     /gene="lepB"
                     /locus_tag="ACL3G6_000597"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGR0545177.1"
                     /translation="MNSLKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKLLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            40482..40604
                     /locus_tag="ACL3G6_000598"
     CDS             40482..40604
                     /locus_tag="ACL3G6_000598"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545178.1"
                     /translation="MKIKEQTRKLAVGCLKQWFEVVDRTDEVSSKYCFEVADGS"
     gene            40681..43047
                     /locus_tag="ACL3G6_000599"
     CDS             40681..43047
                     /locus_tag="ACL3G6_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HGR0545179.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGEQKRQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLTNQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGVALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(43095..44378)
                     /gene="tig"
                     /locus_tag="ACL3G6_000600"
     CDS             complement(43095..44378)
                     /gene="tig"
                     /locus_tag="ACL3G6_000600"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HGR0545180.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
BASE COUNT        13008 a        10182 c         8417 g        12970 t
ORIGIN      
        1 aaataaaaag aaaaggctgc atcaaccgtg cagtcttttt gctgtcctca aaatgaaaag
       61 gcagattctc tatctctact acttgaaggt caagaatcca ccgttatcca aagattaatc
      121 ttcaaatttt tcatgatttt tttcatagaa atcaattaag cctagggctg tttcaaatga
      181 aatatttttt acttttgcac gaccctgcgc cagagcaatg atagacattt cacgcgcatt
      241 cgtttcttta gagatacggt agcctgtgat tttcttatca cgaacccagc caacaactga
      301 ttctactttt tcaaagtttg acttagccat gtttttctcc tattttcttc tttataatat
      361 ttaattgtat acgtttttac tacttttgtc aataaaaaaa acatatattc aacgaaaata
      421 attagttcag aattttctta cttccttttt aaatccgata atatataggt tttgctagcc
      481 tctacaccat aaatatttgc taataaaaat actgtattat taccctctta aggtgcgaaa
      541 ttattcaagt tcttaaaaaa tgcttctcta tttccgtaag atagcttatt tcttcgattt
      601 aagaactgaa gatgatagtt ctaaccttta gaaatccaag ccttctctag ctcaaaaact
      661 cctatctttc ttcctcaata aatcatctga gagataggta ttccttatat ccttcaaatt
      721 catcactcct ttggatattg aggtgctagc ctagaagcag acacccgatt atctaaacca
      781 tccttaatag agatgacaag acagataagc tcagttaatt acttatatat ctttttaata
      841 tggtatattt gtcaacaaaa agaaatcaaa tcatacctta tactcaatga aaatcaaaga
      901 gcaaactagg aagctagccg caaattgctc aaaacactgt tttgaggttt cagatagagc
      961 taacgtggtt tgaagagatt ttcgaagagt attaaagaca gtatgactat gcttgtcaat
     1021 agataggaaa tcaaaatgaa ggatggaaat ctgagccaaa catcataagt gctataatga
     1081 acagaagtaa gaattgcacg ataagttttc taaaaccata ggaatcgtcc cctttcttca
     1141 tcttcattat agcacatata catcagttgt acaaataata tgatattttt ttattagtcc
     1201 tcagacaagc atattataaa gcgtttcatt accatttaag ttaatataag ctggatcaaa
     1261 accttccatt ctacggatca aacctgcata atcatgctta tctgccaaag cgatcccaat
     1321 caatactggg cctgttccct tgctagctcg tttgatatac tcaaaacgtg tgatatcatc
     1381 atttggcccc aggatatcat ttacaaactc acgcaaagct cctggacgct gtgggaaatt
     1441 gaccacaaag taatgtttga taccatcata aatcaaggca cgctcttcca tttctggcat
     1501 acggttgata tcattatttc ctccagaaat gatacaacaa atggttttcc ccttaatata
     1561 ttcagctaaa acctctaaag aggcgatact agccgctcca gcaggttctg cgactatccc
     1621 ttgcttagag taaaggtcaa tcaaggtttc agaaatcaat ccctcatcga cacctaccaa
     1681 agtttgaata tgttgacgag ttgcttcata ggtcaactga cctacctttt gcacagcaat
     1741 cccatccgca aatttatcaa tttccttgag tttgactgga cctccagcct caaaggcagc
     1801 tttcatggaa cgcgctccat tcgcctctac tccgataacc tcaatctctg gacttgtttc
     1861 cttgatatag gtagaaaccc cggcaatgag accgccacca ccaacaggaa ccaagacagc
     1921 atcaaaatca atcgattctt ttcgagcttc ttctaaaatc tcataagcaa ctgttccttg
     1981 acctgcttga acatgagcat catcaaaagg atcaataaag gtacgatttt cagagactgt
     2041 aaattcttga gctgctttgg ctgaggcatc aaaggtatct ccaactagtt taatagttac
     2101 aaaatcccca ccaaaaaagc gaacctgacc aatcttttgt tgtggcgtag taataggcat
     2161 aaagatagta gcaggaattt tcatttcatt acaagtatag gctactccct gcgcatgatt
     2221 tcccgcagaa gcgcagacta ccccacgttc acgttcttcc ttgctgagct gggaaatggc
     2281 ataataggca ccacgaattt taaaggagcg aacacgctgg gcattttctt ttttcaaata
     2341 aatcttagca ccatacttct ccgataaata atgatcgtaa tccagtggag tattcacaac
     2401 cacaccgttc aagaccttgt gagccttgat tatatctttt gaacttaaca tataaaacct
     2461 ctttttctat aaaaaacagt cactaatgac tgttttttag ttattcatct ccgaaaactt
     2521 cagtaacact ttcatggtat ttatgagcca tacgaatcga aaactcttta ggaagttcat
     2581 aacgatttgt ggaaatccaa tcatataacc attctaccaa actttcttca ctatcattac
     2641 gatggaagat aaaatagttt aaaatttctt tatattctac atcattcaaa tccaacgtgt
     2701 ctacaaattg actacgagga acaaaattag aatctaattt tcttagttga tctgtcaatt
     2761 ctcccaattg taaatccaac tgaaaaaata gtttttgcag ttgcctatca gtttcatcac
     2821 atcctgtctt gatagaaaac aaattggtaa tattcatatg atttcaaccc ctaaataagt
     2881 acatctaata tcccacgaat agctgaagct aaagttttcg cagtccagtc atttaaaccc
     2941 gattctttca atccagatgc aataatttgc tctatttgat ataaaccgcc atctatcgtc
     3001 tcatttattc tgcgaagagg accttcaata taggataaag cttctccgaa tctaacagct
     3061 gatttaggtc ctaatgattt accaactata tttgttaatg ttttttattt ctcaaaatcc
     3121 atttcgctat ataacgagca gatttagtcg caccagctct ctcaaacgga gaatgaattt
     3181 caagaccttc ttctctagct atttgtgcca atttgaagaa ttgttcaaag gtcatatgca
     3241 acctaccatc ttcaaaatta gcatcatcat aaatgttaat tacagcattt tcatcatacg
     3301 accaatctgc tttattttgg tctgctagca ctattaccga cggtgtaatt acattataca
     3361 actagaacca ataataacga tgcaattttt ctcataatct ttttcataaa atcatctcca
     3421 gcgctatata tttctaatta gttatagatt ttgaatgcat catcgtcgtt tttaccaaca
     3481 aatggcattg ctttacgcaa ttctgcacca actttttcaa tttcaaggtt agctgcttgt
     3541 tcacggtaag cagtcaattt tggacgtcca gctttatagt catttacaaa gtcatttgca
     3601 aatttaccat tttggatgtc tgccaagaca gccttcatat tttctttaac ttgttcagtg
     3661 attacacgtg aacctgatac atagtcaccg tattcagcag tgtttgaaat agattgacgc
     3721 attttcttga atccaccttc gtagatcaag tcaacgatca atttcatttc gtgaagaact
     3781 tcaaagtaag ccaattctgg agcgtaacct gcttctgtca agacttcgaa acctgcttcg
     3841 ataagggcag tcaaaccacc acaaagtaca gcttgttcac caaacaaatc ttcttcagtt
     3901 tcttctttgt aagttgtttc aagaagacct acacgagccg ctccaacacc tttacaccag
     3961 tccatagcaa tgtttttagc atttcctgtt gcatcttggt atactgcata aagagctgga
     4021 acaccaaatc cttcttcgta agtacgacgt accaagtgtc ccggtccttt aggagcacac
     4081 atgaagacat ctacatccgc aggaactttg ataaattcaa agtggatgtt gaaaccatgg
     4141 gcaaatccaa ctgcgtttcc agcttccaag tttggagcga tttctgcttc gtacaattct
     4201 tgttgaattt cgtctggcgc caagatcatg ataacatcag ccaacttagt agcttctact
     4261 actgtgtaag tatcaaatcc atcttctttt gctttatcaa aagatttacc tggacgtaca
     4321 ccgataataa cgtcacgacc tgaatcacgc aagttttgag catgcgcatg tccttgtgaa
     4381 ccataaccga taacggcgat ttttttaccg tcaagtgctg ctactttaac atctttttca
     4441 tattccattt gaactgtcat agcttttctc tcttttctat tatttattgc cttttaggct
     4501 ggtttaataa atttaagttg gatttttaat cgcgggtaaa tccagttgca cccgttcgag
     4561 caatattgcg aataccgtat gggcgaatga ctcgcaatag ggcttcgctc ttttctgcat
     4621 ttcccgtcat ctgaatggta atcgagcttg gcgctacgtc taccactgtt gcacggaaag
     4681 gttgaataat cgctaaaatc tcagctctct tctcagctgg cgctgacatc ttaaccaaaa
     4741 tcacctcgcg ctccaaatga ggcttgtctg taatatctcg aatgcgaatc acatcaatct
     4801 gacgattgag ctgtttgatg atttgctcca cttcatcatg agaagcaaca tcaataataa
     4861 tagtgatacg cgatacattc ggatcttctg ttgctccaac agagatgctt tcaatattaa
     4921 cctgacgacg agataggaca cctgtaaagc gattgaggac tcctgaacga ttttgtagtt
     4981 ttgctgttaa cattctacgc atggaactgc acccccaaca tctcatgatt actcttacca
     5041 gccggtacca ttggtaacac ctgttcctta cgagaaatat ctacctcaat tagcatagga
     5101 acatcctcag tgatgacttc aaggtcttga gccaaggtct caggattgtc aaacttatag
     5161 tttttaatac cataagcctg cgccatcaat tggaaatcag gaagggtatc aaagaccgac
     5221 tctgatgttc tgccttcata gaaggattcc tgccactggc gaaccattcc aagtgaatga
     5281 ttgttcagca taaccacctt gattggcacc ttgtaaatat tcaaaatagc caactcctgg
     5341 ttggtcattt ggaaaccacc atccccaaca aacaagacta cttccttatc tgggttagca
     5401 attttagcac cgattgctgc tggaattcca aagcccattg ttcccaaacc acctgaagtc
     5461 actaactgac gctcattttg gtagggataa tactgagctg tccacatttg gtgttgacca
     5521 acgtctgtta ccacaatggc atctccattc gtcaattcac caattcgttc aataactgct
     5581 tgcggttgaa ccacacgctc tttcttgtca taagaacgaa cacgattctt gtctttagtg
     5641 actttctcaa tccacttttc agtattgttg tgaactgttg gttctgctag caacatttgc
     5701 aaggccttct tagcatctcc aactacagga atgtctgcac tgataatctt gccaatctca
     5761 gctgggtcaa tatcaatgtg ggcaacctta gcattcttag cgaaagtctt aggattcccc
     5821 gtcaaacggt catcgaaacg agaaccaata ctaatcataa agtccgcttc cgtcatggca
     5881 atatttgctg cgaatgaccc gtgcatgcct cccattccaa gaaagagtgg gtgactcgtt
     5941 gcaatcgttc cttgtcccaa aagactggtt accactggaa tttgatagcg ttctgcaaat
     6001 tcatttagtt ccgtagcagc ctcagcataa ctaattccac caccagctaa caagactggc
     6061 tttttagcct tggacaattg cttcaagatt ttcttgattt gcatatcatt cggctcaaga
     6121 gtcggctgat aacttggtaa attcacttct ggtgaataaa tgaagtctgt ttctaaagca
     6181 gatatgtctt ttggtaggtc aattacaact ggccctggac ggcctgtagt tgcgatatgg
     6241 acagcttccg taatgatacg cggaatatca gctgtctcac gaacttggta attgtactta
     6301 gtgattggca tggtaattcc tacgatgtct gcctcctgaa aggcatcctt cccaatccct
     6361 gctcgcgcca cctgacctgt aaagaccaaa aggggaacgc tatcgctcat agcatccgca
     6421 atccctgtaa tggcatttgt tgctcctggt ccactagtga cgacggcaac acccaacttt
     6481 ccagttgatt tggcataacc ttcagcttca tgcaaacaac cttgctcatg gcgccctaga
     6541 atgtggcgaa tgcctttaaa attatatatc gcatcataaa aaggcaaaac cgcaccacca
     6601 ggataaccaa agatggtatc aactcctaaa tcacgaagtg tttccaaaac taggtccgac
     6661 cccgtcttag gagattctaa actgattttc tccattgttc ccctttcttt cctcttaaaa
     6721 ataacttgtt actatcatac cattttttca aaatttttca agataaaaga agaaattttc
     6781 tgaattttct attttaacgt ttatttatga atgttatttt tgtttttatt aaaaagatac
     6841 cgatttcatt tactaaaaaa gaaaaaagaa ctgatttctc agtccttcat taatcttatt
     6901 ccacactaaa taggtatggg taaacaggtt gttgaccttg gtgaatctcg acttcaacgt
     6961 cttcgaattc ttctacgatt tcttgagcga tttcattggc aagttcttcg cttccgtctt
     7021 caccgacata gaaggttacg atttcactat cttcatccaa catatgtttc aaggtttcag
     7081 tcaatgtttg gtgcatatca gggtttgaca caagaatttt tccatccacc atacctagat
     7141 tatcgttttc atggatttct aagccatcga tcgttgtatc acgcacggct gttgtgacgc
     7201 ttccgctaac gacatcgcta agagcagctg tcatacgctc ttggttttct tcaatggact
     7261 tgcttggatc aaaggcaaga agacttgtca taccttgagg aagagtgcga gcctctacca
     7321 ctactgctgg ttgctccaaa acttctgccg cagattgagc tgccatgaag atgttcttgt
     7381 tgtttggcaa gaagatgatg ttacgggcat tgacctgttc aacagccttg ataaagtctt
     7441 ctgttgaagg gttcatggtt tgaccgcctt cgataacata atccacgcct tgagaacaga
     7501 agatatctgc tagaccttta ccagccacca cagcaatcaa agcatactct ttttcttcag
     7561 ccgacttgat aacttgagta gcttctttct caacctgtgc ttcgtgttgg ttacgcatat
     7621 tgtcaacttt taccttgacc aagctaccat atttgagacc ttcttgcata acaagtcctg
     7681 gatcttctgt atgaacatgg actttgacaa tttcatcatc gttaacaacg aggagagaat
     7741 ccccaagctc atccaagtag ttacggaatt catcgtagtc aaaatcttta gcataggttg
     7801 gaccttgctt aagagctacc atgatttcag tacagtaacc aaacgtgatg tcctcagtcg
     7861 ctacgtgacc agctacagac ttatgatgct ctacattgat catctcactc atgttggcag
     7921 gagtcgctac aaagtcctca gatgcaatat attcgccagt aagggctgaa aggaaacctt
     7981 cgtagatgaa gaccaatcct tgaccacctg agtccacaac gccaacttct ttcaatactg
     8041 gaagcatgtc tggtgtttta gctagagctg ttttagcacc ttccaaggct gcgcgcatga
     8101 cttcaacagc gtcatctgtt tgctcagctt ttttcttagc accgatagca gctccacgag
     8161 aaactgttaa aatcgttcct tcaacaggtt tcatcactgc cttataggca acttccacac
     8221 ctgattggaa ggccagagcc aagtcttgac ctgttaactc gtctttatcc ttgatagctt
     8281 gggaaaatcc acggaaaagc tgagacgtaa tcactcctga gttcccacgc gcacccatca
     8341 aaagcccttt ggcaagaatg ctcgctactt ctccaactgt agaagctggc ttgtctgcaa
     8401 cttctttagc accattttca atggtcattc ccatatttgt cccagtatct ccatctggaa
     8461 ctggaaagac gtttaatgaa ttgacatatt cagcttgctt attcaagcga gttgatgcag
     8521 cctgcaccat ttcttgaaat aagctagtag taatttttga cacggttatt ctcctacaac
     8581 tttgatattt tgaatgtaga catttacagt ctgagcagta attccaagct ggttttccaa
     8641 gctaaaggca acacgctctt gaatgttttt tgacacttca ctaatctttg ttccgtagct
     8701 taacacggta tatacatcaa ctgcaatact gccatcttcg gctgccttta cgacgacacc
     8761 tttagaataa ttttccttac ctagcagggc ttggaaatta tctttgaggg catttttact
     8821 agccataccg accacaccaa aaatctcagt tgctgctcca cctacgacgg ttgcaatcac
     8881 ttcatctgtt agttcgattt gaccatcttt tgtattaatt tttacagtca tcctttttac
     8941 ctcaactagt tgatactcta ttttatcata tttcagccca agtgtaaaag cagaatgatg
     9001 tatcagcgga tatttactct atttttcaaa cgatgttata cccacaataa aagaaaaaag
     9061 accctaaggt ctcctttgct tttattatta aacgcgttca actttacctg atttcaaagc
     9121 acgagctgaa gcccaaactt ttttaggttt accatcgata agaacagtaa ctttttgaag
     9181 gtttggtttt acggcacgtt ttgtttggtt catcgcgtgt gaacggttgt ttcctgatac
     9241 agtcttacga cctgtaaagt aacatacttt agccattgtg ttttcctcct attagatcta
     9301 atatagcgga tgtgctagca ccacataccg tactatgtta tcacactttc ttgttttttg
     9361 caagggaatt ggaagatttt ttatttgtgt cttaaatcag gtcttgcgtg acattttctg
     9421 ctctccacat gccattgttg attaacagaa caccagaatt aaaattatgt gtataaaaat
     9481 catctctaac tgcagctaag ggtatagccg tcaagtccaa atcccacagc tcatctatcg
     9541 attttcttac aacaatatct aaatccaaat acagtacacg agactcgctt acatactttg
     9601 gaataaaata cctaaaaaag ccgcatatga aagtccctca aaggggagac gataaccttt
     9661 cagaatacta ctgtcaatct aaacattcac aatctcacta ttcaaagtct ctagtctttt
     9721 ttccatcaat tggaaccatt ctcgcggaag gtcatcatta aaaacataaa acttaagatt
     9781 ataatagatg aacacaaaga gattttattg ttgtttcaac tttatccata taagcattat
     9841 ctgcacctaa gacaatcgct tttttctctt ctttcactct ttatctcatt tctttttatt
     9901 cccatcatat gtttctacgt aaccattatt ttcgcccatt cgttcgtaaa accataccag
     9961 tggagatttt agatgaagtc ccattacggt ttacaatttt tacattacga cacggagttt
    10021 tacaaatcga tttcatttgc caaacgtagt tagtaaggca gttagctagg ctacctactt
    10081 tctgctacga cggaaaaatc cacaaatcaa taccattcgt ggatttttcc tagtgaagcg
    10141 tttaggtaag ccgccatagc ggttaccgat tattagatta cgacacggag tttggcaaat
    10201 cgattctatt tgccaaacgt agttagtgag gcagttagct agttcgccaa atagcgacta
    10261 gcgtccaaca atttggaact ttagttccaa ttgttggtac tgagtcacat cttctcctct
    10321 aactctacgt ctggatactt gtccgcaaac cagcggaggg caaagtcatt ttcaaagaga
    10381 aagactggtt ggtcaaaacg gtctttggct aagatattgc gacttgatga catccgttca
    10441 tccaaatcct caggcttgat ccaacgaacg gtctttttac ccattgggct catgaccact
    10501 tccgcattat attctccttc catacggtgc ttaaagactt caaactggag ttgacctaca
    10561 gcgcctagca tgtactcacc tgtttggtaa ttcttataaa gctgaacggc tccttcttgc
    10621 actagttgct caatcccctt gtggaaggat ttttgcttca tgacattctt agcagaaact
    10681 ttcatgaaaa tttcaggagt aaaggttggc aatggttcaa attcaaattt gtttttccca
    10741 actgtcaagg tatccccaac ctgataagtg cctgtatcgt aaaccccgat aatatcacct
    10801 gccacggcat tggtcacatt ctcacgactt tccgccataa actgggtaac attagacagt
    10861 ttagccccct taccagtacg agggagatta acactcatgc cgcgctcaaa ttcgccagat
    10921 acgatacgga caaaggcaat acggtcacgg tgacgagggt ccatgttggc ttggatttta
    10981 aagacaaagc ctgagaaatc cttgtcataa ggatccacaa tttcaccgtc tgttttcttg
    11041 tgaccatgtg gttctggagc aaacttgagg aaggtttcaa ggaaggtctg cacaccaaag
    11101 tttgtcaggg ctgaaccgaa aaagacaggc gtcaattctc cagccagaat agcttcctct
    11161 gaaaactcat tcccggcttc atttaaaagc tcaatatcat ccttgacttg ctcgtagaaa
    11221 ggattgctac caaaaagttt gtccccatct tctagactag caaaacgctc atccccttta
    11281 taaagctcta aacgtttgtt atagaggtca tacaagccct caaaggcttt ccccatcccg
    11341 ataggccagt tcatagggta gctagcaatg cccaagattt cttccaattc ttgtaagaga
    11401 tccaaaggct cacgaccgtc acggtccagc ttgttcataa aggtaaagac tggaatgcca
    11461 cgatgtttca caacctcaaa caatttcttg gtttgagcct cgatcccctt ggcagagtcc
    11521 acgaccatga ccgcagcatc caccgccatc aaggtacgat aggtatcttc tgagaagtcc
    11581 tcgtgccctg gcgtgtctaa gatattcacg cgcttgccgt cgtagtcaaa ttgcataaca
    11641 gatgaagtaa cagaaatccc acgttgcttc tcgatatcca tccaatcaga tttagcaaaa
    11701 gtccctgttt tcttcccttt taccgtacca gcctcacgaa tttcaccccc aaagtagagt
    11761 aactgctcag tgatggttgt tttccccgcg tccgggtggg agataatggc aaaggtacga
    11821 cgtttcttaa tttcttcttg aatattcata agttctcttt ctttgattct ctatttttct
    11881 tgtttcaata gctgagaatg atttttacat tggattttac cattcctttc aacactccat
    11941 tatatcggat tttagcattt ttttcaattt ctatttcttt tcacttcccc ctcccttatt
    12001 tataggaaaa tatggtaaaa tagaacagac taaaaatcat catttcacga aaggatgcaa
    12061 gatgaaaatt acgcaagaag aggtaacaca cgttgccaat ctttcaaaat taagattctc
    12121 tgaaaaagaa actgctgcct ttgcgaccac cttgtctaag attgttgaca tggttgaatt
    12181 gctgggcgaa gttgacacaa ctggtgtcgc acctactacg actatggctg accgcaagac
    12241 tgtactccgc cctgatgtgg ccgaagaagg aacagaccgt gatcgcttgt ttaaaaacgt
    12301 acctgaaaaa gacaactact atatcaaggt gccagctatc ctagacgatg gaggagatgc
    12361 ctaatgactt ttaacaataa aactattgaa gagttgcaca atctccttgt ctctaaggaa
    12421 atttctgcaa cagaattgac ccaaacaaca cttgaaaata tcaagtctcg tgaggaagct
    12481 ctcaattcat ttgtcaccat cgctgaggag caagctcttg ttcaagctaa agccattgat
    12541 gaagctggaa ttgatgctga caatgtcctt tcaggaattc cacttgctgt taaggataac
    12601 atctctacag acggtattct cacaactgct gcctcaaaaa tgctctacaa ctatgagcca
    12661 atctttgatg cgacagctgt tgccaatgca aaaaccaagg gcatgattgt cgttggaaag
    12721 accaacatgg acgaatttgc tatgggtggt tcaggtgaaa cttcacacta cggagcaact
    12781 aaaaacgctt gggaccacag caaggttcct ggtgggtcat caagtggttc tgccgcagct
    12841 gtagcctcag gacaagttcg cttgtcactt ggttctgata ctggtggttc catccgccaa
    12901 cctgctgcct tcaacggaat cgttggtctc aaaccaacct acggaacagt ttcacgtttc
    12961 ggtctcattg cctttggtag ctcattagac cagattggac cttttgctcc tactgttaag
    13021 gaaaatgccc tcttgctcag cgctattgcc agcgaagatg ctaaagactc tacttctgct
    13081 cctgttcgca tcgccgactt tacttcaaaa atcggccaag acatcaaggg tatgaaaatc
    13141 gctttgccta aggaatacct cggtgaagga attgatccag aagttaagga aacaatctta
    13201 aacgcggcca aacactttga aaaattgggt gctattgtcg aagaagtcag ccttcctcac
    13261 tctaaatacg gagttgccgt atactacatc atcgcttcat cagaagcttc atcaaacttg
    13321 caacgctttg acggtatccg ttacggctat cgcgcagaag atgcaaccaa ccttgatgaa
    13381 atctatgtaa acagccgaag ccaaggtttt ggtgaagaag tgaagcgccg tatcatgctg
    13441 ggtactttca gtctttcatc aggttactac gatgcctact acaagaaggc tggacaggtc
    13501 cgtacactta tcattcaaga tttcgaaaaa gtcttcgcgg attacgattt gattttgggt
    13561 ccaactgctc caagtgttgc ctatgacttg gattctctca accatgaccc agttgccatg
    13621 tacttagccg acctattgac catacctgta aacttggcag gactgcctgg aatttcgatt
    13681 cctgctggat tctctcaagg tctacctgtc ggactccaat tgattggtcc caagtactct
    13741 gaggaaacca tttaccaagc tgctgctgct tttgaagcaa caacagacta ccacaaacaa
    13801 caacccgtga tttttggagg tgacaactaa tgaactttga aacagtcatt ggacttgaag
    13861 tccacgtaga gctcaacacc aattcaaaaa tcttctcacc tacttctgcc cacttcggaa
    13921 atgatcaaaa tgccaacact aacgtgattg actggtcttt cccaggagtt ctgccagttc
    13981 tcaataaagg ggttgtcgat gccggaatca aggctgctct tgccctcaac atggacatcc
    14041 acaaaaagat gcactttgac cgcaagaact acttctatcc tgataacccc aaagcctacc
    14101 aaatttctca atttgatgaa ccaatcggat ataatggctg gattgaagtc gaactagaag
    14161 acggtacgac caagaaaatc ggtatcgaac gtgcccacct agaggaagac gctggtaaaa
    14221 acacccatgg tacagatggc tactcttatg ttgacctcaa ccgccaaggg gttcccttga
    14281 ttgagattgt atctgaggca gatatgcgtt ctcctgaaga agcctatgct tatctgacag
    14341 ccctcaagga agttatccag tacgctggca tttctgacgt taagatggag gaaggttcga
    14401 tgcgtgtgga tgccaacatc tcccttcgtc cttatggtca agagaaattc ggtaccaaga
    14461 ctgaattgaa gaacctcaac tccttctcaa acgttcgtaa aggtcttgaa tacgaagtcc
    14521 aacgccaggc tgaaattctt cgctcaggtg gtcaaatccg ccaagaaaca cgccgttacg
    14581 atgaagcgaa taaagcaacc atcctcatgc gtgtcaagga aggggctgct gactaccgct
    14641 acttcccaga accagaccta cccctctttg aaatttctga cgagtggatt gaggaaatgc
    14701 ggactgagtt gccagagttt ccaaaagaac gtcgtgcgcg ttatgtatct gaccttggtt
    14761 tatcagacta cgatgctagt cagttgactg ctaataaagt cacttctgac ttctttgaaa
    14821 aagctgttgc cctaggtggt gatgccaaac aagtctctaa ctggctccaa ggggaagtcg
    14881 ctcagttctt gaatactgaa ggtaaaacac tggaacaaat cgaattgaca ccagaaaact
    14941 tggttgaaat gattgccatc atcgaagacg gtactatttc atctaagatt gccaagaaag
    15001 tctttgtcca tctagctaaa aatggcggtg gcgcgcgtga atacgtggaa aaagcaggta
    15061 tggttcaaat ttcagatcca gctatcttga tcccaatcat ccaccaagtc tttgccgata
    15121 acgaagctgc tgttgccgac ttcaagtcag gcaaacgtaa cgccgacaag gcctttacag
    15181 gattccttat gaaggcaacc aaaggccaag ccaacccaca agttgccctt aaactacttg
    15241 cacaggaatt ggcgaagttg aaagaaaact agacagaaca aaaccagccc taaggttggt
    15301 tttttcttct ctcccaactc ccaataacta ttttggcttt atttccagag tattttatgg
    15361 taaaatgaag agtaataata tttattaaag aggtaaaaac atgattgaag caagtaaatt
    15421 aaaagctggt atgacctttg aaacagctga cggcaaattg attcgcgttt tggaagctag
    15481 tcaccacaaa ccaggtaaag gaaacacgat catgcgtatg aaattgcgtg atgtccgtac
    15541 tggttctaca tttgacacaa gctaccgtcc agaggaaaaa tttgaacaag ctattatcga
    15601 gactgtccca gctcaatact tgtacaaaat ggatgacaca gcatacttca tgaatacaga
    15661 aacttacgac caatacgaaa tccctgtagt caatgttgaa aacgaattgc tttacatcct
    15721 tgaaaactct gatgtgaaaa tccaattcta cggaactgaa gtgatcggtg tcaccgttcc
    15781 tactactgtt gagttgacag ttgctgaaac tcaaccatct atcaaaggtg ctactgttac
    15841 aggttctggt aaaccagcaa cgatggaaac tggacttgtc gtaaacgttc cagacttcat
    15901 cgaagcagga caaaaactcg ttatcaacac tgcagaagga acttacgttt ctcgtgccta
    15961 atctctagaa agaggtcatt ctatgggaat tgaagaacaa cttggcgaaa tcgttatcgc
    16021 cccacgtgta cttgaaaaaa tcattgctat cgctactgca aaggtagagg gtgttcactc
    16081 tttttcaaac agatcagtgt ctgataccct ttcaaaactt tcactcggcc gtggcattta
    16141 tcttaaaaac gtggacgaag aactcacagc agatatctat ctctaccttg agtacggagt
    16201 aaaagttcct aaggtagcgg ttgctatcca gaaagctgtc aaagatgccg tccgtaatat
    16261 ggctgatgta gaactcgctg ctatcaatat tcacgttgca ggtatcgtcc cagataaaac
    16321 accaaaacca gaattgaaag atctatttga cgaggacttc ctcaatgact agtccactat
    16381 tagaatctag acgccaactc cgtaaatgcg cttttcaagc tctcatgagc cttgagttcg
    16441 gtacggatgt cgaaactgct tgtcgtttcg cctatactca tgatcgtgaa gatacggatg
    16501 tacaacttcc agcctttttg atagacctcg tttctggtgt tcaagctaaa aaggaagaac
    16561 tagataagca aatcactcag catttaaaag caggttggac cattgaacgc ttaacgctcg
    16621 tggagagaaa cctccttcgc ttgggagtct ttgaaatcac ttcatttgac actcctcaga
    16681 tggttgctgt taatgaagct atcgagcttg caaaggactt ctccgatcaa aaatctgccc
    16741 gttttatcaa tggactgctc agccagtttg taacagaaga acaataaaaa gaaaaagtgt
    16801 ttgatagata tcaaacactt ttttctttgc ctcccactat ctaaaaaaat gataatagat
    16861 ataattgtaa acaaaaatcc agataggttt tgcatgattg agaaagttaa aaaaactatg
    16921 gcagagaatc gttaatctca gattgtcggt agaacgataa acaagggcaa aaaagaaacc
    16981 aatcagacta taatataata aactaattgg atctctgtga gatagtatca aatggctaat
    17041 cccaaagatg atagcagata ggataacatc caaatagtac ttggactagg gaaagaaggt
    17101 attcataaaa taccctctat caagagtctc ctcaaaaaca ggaccgatga ttacaggcag
    17161 gacaaaagat aagatagtcg ataaaaaggt tggttgtcca tttgaaaaaa gcacggtaaa
    17221 atactcatca tgaatattcc tatgattaat caaatgagca tagcgtgccc aaaaattacc
    17281 gagaatctga taaaccacat aagttgcaaa taagtagaag acaaatgacc agttccagct
    17341 ctttttctca aagataaaga gcatcttttt cttttttaac ctccaaatta atagaaggaa
    17401 acttcccact aatcccattg ttaaaataag agaatagaca tcagctccta accctaaaat
    17461 gatcgtcaca tacaatccaa ttgtttgtgg taaataggta gatagtaaaa taataagcaa
    17521 aaatattcca aattgtctta gtttttttgt gtttctcatc gtactttttt gaaagattac
    17581 cctgctcgga agccgtactt ccaagcatct atataagaat taagtgcccc ttgcctcata
    17641 tagggagcaa attctctata atataaccat ctactatatc catcttccca aacagcaaga
    17701 ccacctgaag tttgctccaa gtcctcagtt gaaagaactg taaatgtatt tgtacctgtc
    17761 attgcaagta ccttcttaaa atagattgtt gtaggttcac atttatagta tatttctttt
    17821 tttgtctatt ttatagccca tctcctcaac tggcaatttt tcgacctgaa ttacattttt
    17881 ccataaaaaa tgagaccttt ctagtctcat ttagtcattc ttagtatttt ctaaatcgtt
    17941 gatagcgttc ttccagcaac tcttctagcg gtttttgtga aagtctagcc agctccgttt
    18001 ggagttcttt tttgacactc ttaatcagtt ctttactaga aagtcctatt tcagaaatca
    18061 ccttatccac cacgtccatt tctaacagtt catgcgaagt gattttcatc agttctgctg
    18121 cttccatagc gcgagtaccg tccttccata aaatggaagc aaagccttct ggactgagaa
    18181 tggcatagat agaattttcc agcatccaga cacggtccgc gacagctaga gccagagccc
    18241 cgcctgaacc accttcaccg ataataatgg cgataatagg aactttcagg tcactcattt
    18301 ccatgagatt gcgagcgata gcttcccctt gaccacgttc ttccgctccg acaccaggat
    18361 aagcacctgc tgtattgata aaggtcacaa ctggacggcc aaatttctca gcctgtttca
    18421 tcaaccgcag tgcctttcgg tagccttctg gatgtggttg gccaaaattc cgtttgaggt
    18481 tgtcttgcaa actcttgcct ttttggatac caaccactgt tacagcttga tctccaagcc
    18541 aaccaatacc accaacaact gcaccatcat cacgaaaaga acggtcacca tgtaattgga
    18601 taaattcatc aaaaatgcct gtcgcaaagt ccaaggttgt caagcgactc tgctcacgcg
    18661 cttctctgac tatttttgca atattcatct aggactccct ccatgcaatc tgactaggct
    18721 agcaatcgta tctggtaagt ctcttctttt gacaatagca tccacaaagc catgttctaa
    18781 taggaattct gccttttgga aatcctcagg caagctttca cgaaccgtat tttcaatcac
    18841 acgacgccca gcaaaaccaa ccaagctctg tggttcagcc agaatgatat cgccttccat
    18901 agcgaaagaa gctgtcacac caccagtcgt tggatctgtc aaaatggtca ggtaaaagag
    18961 accagcattt gaatggcgtt taaccgccgc agagatctta gccatctgca tgagactcat
    19021 gattccttcc tgcatacggg ctccaccaga ggctgtgaat aggacaactg gcaatttttc
    19081 gacagtcgca tactcaaaca aacgagtgat tttttcacct acaaccgtac ccatagaagc
    19141 catgataaag ttagaatcca taatcccaag agccacagtc tgacctttaa taagagcagt
    19201 tcctgtcaca acggcttcat gcagacctgt tttttcacgc atagatgcca gtttcttttg
    19261 gtaaccaggg aaatgcaagg gatccttgct ttcaatccct gtaaacaatt ctttgaaggt
    19321 tcccatatca atcgtcaaag ccaagcgttc ttgggcagaa atacgaaagg tatagctaca
    19381 gtgcggacag atacgttcac ttcccagatc cttctgatag atggtatgct tacagcctgg
    19441 acactgggaa aataattcat ctggaacctc tggcttagct tgaggttttt ccctaaccga
    19501 acgattggga ttgattcgaa tatacttatc ttttttacta aatagagcca ttgattcccc
    19561 ttttcggttt aaactcttaa agtcatttta ttctttttct tgatatttag gtaagaaggt
    19621 ttccatcaag aaggaagtat cataatcccc agcaatgaca ttgcgatctg aaatgaggtc
    19681 aagctggaaa tctgcattgg tctgcactcc ttcaatctct aattcataga gggcacgttg
    19741 cattttcatc aaggcgtcaa aacgattttc gccgtgtact atgattttgg caatcatact
    19801 atcataataa ggcggaatgg tataacctgg ataaactgct gaatccacgc gcaagccaac
    19861 tccaccactt ggcagataga gattagtaat cttacctgga cttggagcaa agttaaaggc
    19921 tgggttttct gcattgatac gacactcgat ggcatgaccg cgtaggacaa tatcttcttg
    19981 cttaacagac aaaggctgac ctgccgcaat gcaaatctgt tccttaacga tatcaacacc
    20041 tgaaacaaac tctgttactg gatgttctac ctgaacacga gtattcatct ccatgaaata
    20101 gaaattgcta cttgcttcat caagaagaaa ttcaatggtt cctgcattct catagccaac
    20161 aaactctgcc gctcgaacag cagcagcacc tatttcatga cgcagcgttt ttccgattgc
    20221 aatcgaggga ctttcttcca aaaccttttg gttattcctt tgaagagaac aatcccgttc
    20281 acccaagtga atcacatgtc catgctcatc acctaggatt tgaacctcaa tgtgccgagc
    20341 tggatagata acccgttcta tgtacatggc accattgcca taattggcct tggcctcact
    20401 agaggcagtt tcaaaggcag aaacgaggtc atctggtttt ttaaccttac gaatcccttt
    20461 accacctcca cctgctgaag ccttgagcat aacaggatag ccaatttttt cagcaacaat
    20521 caaagcttct tcagagttat gcacttctcc atctgaacct ggtataacag gcacacctgc
    20581 tttaatcatc tgagcacgcg cattgatctt atcccccatc atatccataa catgaccaga
    20641 tggaccgata aacttgatac ctacttcttc acacatggtc gcaaatttgg aattttcact
    20701 gagaaatcca aaaccagggt gaatagcttc tgcctcagtc aagactgcag ctgatagaac
    20761 tgcattaata ttgagataag actctgttgc cttgccagga ccaatacaaa ctgcttcatc
    20821 tgccaaaagc gtatgaagag cttccttatc agcagttgaa taaaccgcta ccgtcgcaat
    20881 ccccaattca cgtgccgcac ggataatacg aaccgcaatt tcaccacgat tggcaattaa
    20941 aatttttcga aacatggaga acctccttag ttcccaattg caaaagtaag ggtaccactg
    21001 gctgcaagct tgccatccac ttcagccttt gcttcaacca cagctatggt gccacgacgt
    21061 tttacaaaag tcgctgtcat aaccaattgg tcgcctggta caacttgctt cttgaactta
    21121 accttgtcca taccagcgta aaagaccagt tttcctttat tttcaggttt tgataactcc
    21181 aacacaccgg cagtttgcgc caaggcttcc ataatcagaa cacctggcat aactgggtat
    21241 tgaggaaagt ggccgttaaa gaaaggttcg ttaatggtca catttttgat agcaacaatg
    21301 gtatcctcgc tcacttccaa gacacggtcc actagaagca taggataacg gtggggaaga
    21361 gcttctttga ttccttgaat atcgatcatt tgatacgtac caatccttta ccaaactcaa
    21421 ccatttcttc gttagagacg agaatttccg ttaccacacc atccttagga gctgggattt
    21481 cattcatgac tttcatggct tcgataatta ccaatgtttg accttttttg acactatcac
    21541 caactgtaac gaaggcaggt ttatctggtc cagcagccaa gtaaaccact ccaacaagtg
    21601 gactctctac aagatttccc tcagtagcca cacttgcttc agctggagct ggaacttctt
    21661 ctgctacagt ctctgctgga gcagatgtag gagctactgg actcggtgtt gctagaacgg
    21721 gtgctggagc gacttgagtt gcaacttcag gcacaggtct tgcttcattc ttgctaaact
    21781 gcaactcatc cgtcccattt ttataagaaa attctctcaa acttgactgg tcaaattgag
    21841 tcatcaagtc tttaatatcg tttaaattca tacttatcta ttctcccaac gtttgaaagc
    21901 aagaactgca ttgtggcctc caaaaccaaa agtatttgaa atagcgtatg gaatttcttt
    21961 ctccaagcct tgtccataaa cgacattagc ttcgatataa tctgatactt cacttgtccc
    22021 agctgtcatt ggtacaaagt tatgacgcat agcttcgatg gtgacgatag cttctactgc
    22081 acccgcagcc cccagcaaat gtcctgtaaa agacttggtt gatgatacag gtacttcctt
    22141 accaagaaca gctacgatag caccactttc tcctttttca ttggcaggag ttgacgttcc
    22201 gtgagcattg acataggcta cttgctctgg agaaatctca gcttcttcca aggctagttt
    22261 gatggccttg atagctccct gaccttctgg atgtggagaa gtcatgtggt aggcatcaca
    22321 agtatttccg taaccaacca cttcagccag gatagtagct ccacgttttt cagcgtgttc
    22381 aagactttct agaaccaaca tccctgaacc ttcacccata acaaacccat tgcgatcctt
    22441 atcaaatggg atcgaagcac gagttggatc ctctgtagta gagagagctg ttaaggcttg
    22501 gaaaccagcg atggcaaaag gtgtgataga agcttctgtt cctcccacca acatcacatc
    22561 ttggaaacca aacttaatgg agcggaaggc atccccaatc gcatcatttg atgaagagca
    22621 ggcagtattg atagatttac aaacaccgtt tgcaccaaaa cgcatggcta cattcccaga
    22681 agccatattt ggtaaagctt ttggaagagt cattggtttg acacgtttgg gtcctttttc
    22741 atgaaggcga agtacctgat cttcaatttc cttgattcca ccaataccag atgcaacgat
    22801 aacaccaaaa cgatccctat taagagcctc tacatcaaga ttggcatgat ttacagcctc
    22861 ttgggctgca tacaaggcat ataaagaata gttatcaaaa cggttggtat ctttttttac
    22921 aaagtattta tcgaacggaa aatcttggat ttctgccgca ttatgcacat caaagtcact
    22981 atgatcaaat tttgtaatgc caccaatgcc gattttccca gttgctaaac tattccaaaa
    23041 ttcttctggt gtatttccga ttggagatgt tactccataa cctgttacca ctactcgatt
    23101 tagtttcatt cttttcacct ctagctttcg ctacatactt aagccaccat caatggcaat
    23161 cacttgacca gttagataat cttggcctgc taaaaatact gtcaaatctg caacctgctc
    23221 tgcctgccca aattctttca tcggaatctg agctagtgta gcttccttaa tcttatctga
    23281 taagatagct gtcatatcag actcaatcat tcctggagca atcacattga ctcgtatatt
    23341 ccgactagcg acctcgcgtg ccacagactt ggtaaagcca atcaagccag ccttagaagc
    23401 agcatagtta gcttgaccaa tattccccat caaaccaaca acactagaca tattaatgat
    23461 agcaccttct ctggctttca tcatcggttt caagactgat tgtgtcatat taaaggcacc
    23521 agtcagattg accttgagca ctttttcaaa atctgcttct gtcatcttga gcataagagt
    23581 atcttgggta atccctgcat tgttgaccaa aacatctact gaacccagtt ctgcaatagc
    23641 ttgatcaatc atacgcttag cgtctgcaaa atctgataca tctcctgaaa tgggaaccac
    23701 cttgatacca tagtttgaaa actcagcgag caattcttct gagattgccc cacgactgtt
    23761 taagacaatg ttggctcctg cttgagcaaa cttgtgggcg atggcaagac caattccacg
    23821 actcgaacct gtaataaaga tatttttatg ttctagtttc atttttttcc tttcaaaact
    23881 tctacttatt ttagtctatt tttctaaaag tgctactaaa ctcgcttgat cttccacatg
    23941 agctaagtga gcagtttgat caattttttt aacaaagcct gacaagactt tccccggtcc
    24001 aatctctata aagttgctta tgcctgcttc ttgcatgacc ccaatacttt catagaaacg
    24061 aacgggttcc ttgacctgac gcgtcaagag ctgagcaatg tcctcttttt gcatcacagc
    24121 agcttctgta ttgccgacta ggggacaagt aaaatctgaa aaacttacct gagctagagt
    24181 ttcagctagt ttctggctag caggctcaag gagagcggtg tgaaagggac ctgacacctt
    24241 aagaggaatc aagcgtttgg cacctgcttc ttgcaaaagt tcaaccgctc gatcaactgc
    24301 aaccacttct ccagcaatga cgatttgtgc aggtgtgtta tagttggctg gagtaaccac
    24361 tccaagttca gaagcttttt gacaggcttc ttcaatgacc tctactggcg tattgagaac
    24421 tgctaccatc ttgccagagt cagcaggagc cgcttcttcc atataggctc cacgcttagc
    24481 taccaaggca accgcatctt caaaatccaa ggcgccgctt gccaccaagg cagagtattc
    24541 tccaagagac aaaccagcaa ccatatcagg ctgatagccc ttttcttgca ataaacggta
    24601 gatagcaacc gaagtcgcta gaatggctgg ttgcgtatag cgggtctgat tgagtttgtc
    24661 ttcttccgta tcgatgagat aacgcaaatc ataacctagt acctggctcg ctcgatcaat
    24721 cgtttcttta acaatcggat actgatcata gaaatcccgt cccatcccta gatactgggc
    24781 accttgacca gcaaataaaa aggctgtttt agtcatttct tacaactcct gtccagcgag
    24841 aggcttcttc ttgaattttc ttagcggctc cgtaatacaa atcttttagg atttcttcag
    24901 ctgtttcttc tttagaaaca agccctgcga tttgacctgc cataacagag ccaccatcca
    24961 catcaccgtg aacaactgct ttggctagag cacctgctcc catttgttca aagatttcta
    25021 aatcaggatc ttcttgctta aaggcatctt tttcagccag ttcaaaatct ctagtcaact
    25081 gatttttaat agcacgaaca gcatgaccaa agtgctgagc tgaaatcgta gtatcaatat
    25141 cccttgcttt taaaattttc tccttgtagt ttggatgggc attcgactct tttgcaacta
    25201 caaaccgtgt ccccacctgt acagcctctg cacctagcat aaagccagcc gcagcacctt
    25261 caccatccgc aattcctcct gcagcaataa caggaataga tacagctgtg gctacctgtc
    25321 gcaccaaagt catggttgtt aatttaccga tatgcccccc agcttccatt ccttctgcaa
    25381 taacagcgtc tgcaccgatt ttttccatgc gtttagctaa agcaacacta ggaacgacag
    25441 gaataacgat tatcccagct tcatggaaac gttccatata cttgcttgga tttcctgctc
    25501 ctgttgtgac aactttaaca ccttcttcaa taacgagatc cacgatatct tccacaaagg
    25561 gagataagag catgatgttg accccaaagg gtttatcagt caatgatttg attttatcaa
    25621 tattggcctt gacaacttct ttcggggcat ttcccccacc gataattcct aatcctccag
    25681 ccttggaaac agcccctgcc aaatcaccat cagcaaccca ggccatccct ccttggaaaa
    25741 taggatagtc aatcttcaat aattctgtaa tacgcgtttt catagtgcct ccaaccttcc
    25801 ttgcttacgt aatagttcga tttcaccata atttgacagt caaactatta cctaaacaag
    25861 agggagtggg tttctcccta ctccttctac ttaatattct gcttattttg cttgctcttc
    25921 aacgtaagca accaagtcac caactgtttt caagtcattt tctgcttcga tttggatatc
    25981 aaaagcatct tcgatttctg agattacttg gaacaagtcc aatgaatctg cgtccaaatc
    26041 atcaaaagtt gattcaagtg ttacttctga tgcgtctttt ccaagttctt caacgataat
    26101 ttcttgtact ttttcaaata ctgccatgat aggactcctt taaaataaat agttttttta
    26161 taacaatgtg ttcaccacat gattacctaa attgtaagaa tgagcgtgcc ccaggtcaaa
    26221 cctccaccga agcctgatag aagaacagtc tggctaccat ctaaagggat gagaccttgt
    26281 tctacacact ctgaaagtaa aatcgggata ctggctgcac tggtattgcc atattccatc
    26341 atattggctg gaagtttggc tcggtcaaca ccaatttttc tagccatctt atccaaaata
    26401 cggtcattgg cttgatgaag tagcagataa tccaagtctg tcacctctat aggagattca
    26461 tcaatagtct gcttgataga cttggctaca tctcgaatgg caaaatcaaa gactgtgcgt
    26521 ccatccatct tcaaaaatga atctgcactt tcttgatctg aaaatggaga atgcaaacct
    26581 gaatgcccat aagttaaaca ctcgctgcga cttccatcgc tattgagact ctcagctaag
    26641 aaatgctctt gctcgctagc ttctaacaag acaccaccag caccatctcc aaacaacaca
    26701 gctgttgatc gatccgacca atcgactgcc ttagagaggg tttcactacc aatcaccaag
    26761 cctttttgaa agcgaccaga agcgataaac ttttcagcag ttgaaagagc aaatacaaat
    26821 ccactgcaag ccgcggttaa gtcaaaagca aaggctttat tagcaccaat attagcttga
    26881 acacgagcag ctgtagaggg catcatcgaa tctggagtaa tggtagctag gatgataaaa
    26941 tccagttctt ttcctgttat tccagctttt gccatcagtt tcttagcaac ctctgtagcc
    27001 aaatcactgg tagattctgt tcttgaaata tgcctttgtc gtattcccgt tcgacttgaa
    27061 atccactcat cattggtatc cataatctga gccaagtcgt gatttgtaac cacttgctct
    27121 ggcacataat gagcaacctg acttattttt gcaaaagcca ttatttcaaa tcctccaaaa
    27181 attggtaaag attagtcaag cctttaccca tgacagcaat ttcttcctcg ctcatgccat
    27241 caataatttt ttctaccatg gccttgtgga agcgtttatg cagtctatga atcaagcgac
    27301 ccttctttgt caaatgcaga tgcaccacac gacgatcctg ttctgaccga actcgctcaa
    27361 tgtagccctt acgctctaaa ttgttcaaac ttgtcgtaac agttccaaga gttaccatca
    27421 actcttttga cacttgactt ggagtcacat ctggagcctt accgatgaca tcaatcgtat
    27481 gcatttcttt gatggagata tccttaaaac gactacctct caagttcact tcctcaatta
    27541 caaggacatt gttaaatata gatgttaaat attcattgat tcgttggtag tccatttttc
    27601 atatccctcc ttcttcaaaa aacttttaca atcaaaacat ttgacagaaa gaattatatc
    27661 aaaattcaaa gaatgatgca agtatttttt attttcctgt aaatttaggt cttcttctct
    27721 ccgaatgagc tcgcactcct tctttgaaat cctctgtttg agctaaggat ttctgtaggt
    27781 tcagttctaa agtagcgtaa ccctgccagt ctttaaattg gctctcccaa accaacttct
    27841 taatggcagc ataggaatta cttgaagcac gtcttaattt tttaagaagc tgttctctcg
    27901 tcttttcaag tttttcagct tcagaaacgc ggtaaaccaa cccccattct agggcttttt
    27961 ctgccgttaa agcctctcct gtcatagcta attgagcagc acgcgtcaca ccgatactgc
    28021 ggctcaagag atgaattccc cctgcatctg gagccaaacc aacaccaaca aaggcttgga
    28081 taaacttagc cttatccgtc gccaaacaga aatctgccgc aacagccata ttcgctgcgg
    28141 cacctgcaac agcaccgtca acttccatta aaacaggttt ggctatttgc ttgattttat
    28201 aagaaatcgt attgaccaac tctgcgattt ttgtcaatga tggaatatca tcctcatcca
    28261 ctgcccgctt catctctacc aaatctcccc caactgagaa gacctttcca ttggcattga
    28321 ttaagataaa atgcacagct ggattttctt ctgccaaagt cagagcttct aaaatctcct
    28381 cacacatggg aatatgaaaa ccatttgcga cctcaggacg gttcaaggta aggattgcca
    28441 agtcctcttc aagctgataa ataatgtgtt ccatcagggc tcctttttat tttataagca
    28501 gtttatactc ttcgaaaatc tcttcaaacc gcgtcagctt ccatctgtaa cctcaaaaca
    28561 gtattttgag ctgacttcgt cagtcttatt tacaacctca aagcagtgct ttgagcagtc
    28621 tgcggctagc ttcctagttt gctctttgat tttcattgag tgttaaatta tttcactgtc
    28681 aaagtatatc ttttttagga gcagaaagca agaaaaaatc gactgaaagt gtctcagccg
    28741 ataagaaagg ctcgctttag gctagaaagc atcttatttt cttcattgaa aaaagccttt
    28801 ctttctgcta taatcgtata aaatacttac tttaggagtt cttatgaaag ttgttaaatt
    28861 tggaggtagt tctcttgcct ctgctagtca attagaaaaa gttttaaaca tcgtcaaaag
    28921 cgattcagag cgtcgttttg tagtcgtttc tgcgcctggt aaacgcaatg ctgaagatac
    28981 taaggttacg gatgccctga ttaaatacta ccgcgactat gttgcgggta acgatattag
    29041 caagagccaa agctggatta tcgaccgcta tgctgctatg gttagtgaat tgggactaaa
    29101 accagctgtg ctagaaaaaa tttctaaaag cattcacgcc ttggccactc ttcctattga
    29161 agaaaatgaa tttctctacg atactttcct agcagccggt gaaaataaca atgccaaatt
    29221 gattgctgcc tactttaacc aaaatggtat cgatgcacgc tatatgcacc ctagagaagc
    29281 tgggattgtg gtcacaagtg aacctggtca cgctcgcatc attccatcaa gttatgacaa
    29341 gattgaagaa ttgacaaaca ccaatgaagt ccttgtcatt cctggtttct ttggtgtcac
    29401 taaggaaaat caaatctgta ctttctcacg tggaggatct gatattacag gttctatcat
    29461 tgctgctggt gtcaaagctg acctctatga aaactttacg gacgttgatg gtatctttgc
    29521 agcccaccct ggtattatcc accaaccaca ctcgattcct gagttgacct accgtgaaat
    29581 gcgcgagttg gcctatgcag gcttctcagt ccttcatgac gaggctcttc ttcctgccta
    29641 ccgtggaaaa attcctctgg ttatcaagaa taccaacaac cctgaccatc caggtactcg
    29701 tatcgttcta aaacacagta atgatgaatt tccagttgtg ggaattgctg gtgactcagg
    29761 ctttgtcagc attaatatgt cgaaatacct catgaaccgt gagattggat ttggccgcaa
    29821 ggttctgcaa atcctggaag aacttaacat cggttgggaa catatgccaa caggtatcga
    29881 cgatctttct atcattctcc gttctcgcca actaactccc atcaaggaag aagaaatcct
    29941 gcgtcagttg gttcaaaagg ctaaagtaga tcatgcagaa atcgaacacg acctttctat
    30001 cattatgatt gttggtgaaa aaatgaagag ccatatcgga gtgactgcta ctgcgacacg
    30061 cgctctatct gaaaacaaaa tcaacatcca gatgatgtct caaggttcta gtgaagtttc
    30121 tattatgttt gttgtcaata aagaccaaga gaaagcagca attaaagccc tctactatgc
    30181 cttttttgga gaaagtaagg aagactaagc atggctcaat cacttaacaa aacagtactc
    30241 ctcagtacga caggcacttc ctacctctct atcgctggga aagttgggaa attccttgtc
    30301 ggagatcagg ctttggaatt ttacccagat gtcaatgtcg aacaatttat ccagattcct
    30361 tggagccata tcaatcagat tggagccaat gtcactggac gcaaagtcag ccgccacttc
    30421 gaagtcttta cagacaaagg aaaattcctc tttgcttcaa aagactcagg tgccattctc
    30481 aaaattgcac gcgaaaaact aggcaatgac aaggtcgtca aacttccgac cctgattcag
    30541 acaattagcc aaaaatttaa aaatctattt gcaaaaaagt agaaacttta gtataatcat
    30601 agcaacggat aagtaggtta tcttcttctt tcagaaagtc tgcgggtact gcgagcagat
    30661 aggggggata ggtgaaattc taccgttagt aacaattaca tacacaatca agtgcacacc
    30721 tgtgaagttg gatggaaccg tggccctgcc actccaacgt tttgtcaggc gtgctttttt
    30781 cataaaggag ttcttatgtt agatatcaaa cgtattcgta cagattttga agctgtcgca
    30841 gaaaaattag ctacacgtgg tgtagatgct gctgtcttga atgaaatgaa agaaatcgat
    30901 gctaaacgtc gtaacatctt ggtcaaggtt gaaactctca aagcagaacg taacacagtt
    30961 tctgctgaga ttgcccaagc taagcgcaac aaggaaaata cagatgacaa gattgctgcc
    31021 atgcaaaatc tatctgctga ggttaaagcc ttggatgctg aattggcaga aatcgatgct
    31081 aaattgacag aatttacaac gactcttcca aatatcccag ctgacagcgt tcctgttggg
    31141 actgacgaag acgacaatgt ggaagttcgc cgttggggta ctccacgcga gtttgacttc
    31201 gaacctaaag ctcactggga tctcggtgaa gaccttggta tccttgactg ggaacgcggt
    31261 ggtaaggtaa caggcgctcg cttcctcttc tataaaggcc tcggtgctcg tttggaacgt
    31321 gctatctaca actttatgtt ggatgaacat ggaaaagaag gctatactga agtcatcaca
    31381 ccttacatag tcaaccatga ttctatgttt ggtactggtc agtatccaaa atttaaggaa
    31441 gatacttttg aactcagcga taccaacttt gtcttgattc caactgctga agttcctctg
    31501 acaaactact accgtgatga aatcttagac ggcaaagatc ttccaatcta cttcactgcc
    31561 atgagtccgt cattccgttc tgaggctggt tctgccggtc gtgatacgcg tggcttgatc
    31621 cgtttgcacc aattccacaa ggttgaaatg gtcaaatttg ccaaaccaga agaatcttac
    31681 gaagaattgg aaaaaatgac agccaacgct gaaaacattc ttcaaaaact caaccttcca
    31741 taccgtgtcg ttgctctctc tactggagat atgggcttct cagctgcgaa gacttacgac
    31801 ttggaagtgt ggattccagc acaaaacaat taccgtgaaa tctcaagctg ttcaaacaca
    31861 gaagatttcc aagcccgtcg tgcccaaatc cgttaccgtg atgaagcaga tggcaaggtg
    31921 aaactccttc ataccttgaa cggttctgga cttgcagttg gacgtacagt ggctgcaatt
    31981 cttgaaaatt accaaaatga agatggttct gtgaccatcc cagaagcact tcgtccatac
    32041 atgggtggag ctgaagtcat caaaccataa aaaataaggt ttagctattt ctagctagac
    32101 cttttttcgt aaccaaatca gataagcacc tagtacaaag aataaaatag ttaggcatat
    32161 aatggtttca gccaatacca ggtaatccag aaatggaagt ttcaaaattc cctgagccat
    32221 cttgagcgag gtcgctgtga taatggttgg gaaggtgagg gctgagaagg ctggttgaaa
    32281 accttgtttt aaaatgttgg gcagacgagt taaaacaaag aaaaagaagg attgagaagc
    32341 caaaatcatg acaatcaaga cccaagtcgg caggctggtt cctcctactc gaactagaga
    32401 agccaagagt agagagaaag gagcacagta gattccttct tgtccaagca aggctagtgg
    32461 gagtggatgt ttctttaaat cgctataaat aaggggatag agatagaagg tcaagagaaa
    32521 accaaaactc aaggtcgcat aggcaatttc gataatacct accagaggat aggtcaaggc
    32581 agccactgct atccccacat agagaaccgt ccagcttgga gtggcatgaa ccctccgccc
    32641 tggacaagca aacttgatgg taaaaccagc aatcaaggtc aaatccaaga gaaatgaaaa
    32701 ccaccaaatc ccttgtgcta ccaaaggaag ataagagaat acgcgaaaga cataggtcga
    32761 taaaatcatc ccagccatag gaaaggttgc cattcctgac aaaagagggg gcttggtcaa
    32821 ttcttgcttg gtttctttcc aattaaagag atgcagaatt agaaagtaaa tccataaaac
    32881 caaaccagtc agactaaaaa gatgggatag aaccggcaac gtatctaaaa taagatttcc
    32941 agctcctgcc aaacctagca aacaacctga aaatactaag gggagttttt tcatcctaac
    33001 ctccaataat catgttagtt tcagtataac ataaaagcgc ttaaatgagg atttaaaaaa
    33061 acgaagtccg attatttcag acttcatttt actcagatat gaattaggca taaggttgca
    33121 attctggatt aattggtgta ttagctaagt tgttggcata gttacagagg attgctaggc
    33181 tgacaccaaa aaccacatcc aaggcatttt gttgagtgta gccagcttct aaaaactcag
    33241 acaaggcttc atctcctaca cgacccttgg tattgataac tgccaaggta aacttagcta
    33301 gggtatccaa tttaggatct gtttcaattg gagtacgatt gcgaagagct tgaatcaagt
    33361 catcattcat ctggatttgt ttgatggaaa aggctgtgtg acctgcgaca cagaaggcac
    33421 aaccattggt cacggctgcc gtgatttgca ccacttcacg ctcaacgggt gtcaggctgt
    33481 tgcgacggtg gatagatgag acaatttggt aggcttctaa aacagtcggg gcattggcca
    33541 agagaccgat taggttggga atatagccat tgttgtcttt ttctactgtt tcaagaattt
    33601 ctttcacttc tgctggtgct gactctactg tatggatagt aaatgttgtc ataagatacc
    33661 tcttttctta ttattgacac taatattatt ggaaaatctt ataaaatcct gattcctaag
    33721 tttatctaag ataaagcttt attctctcat aagattttcg ttgttatatt agtttatcac
    33781 acttccaatc acttgcataa tatatattat atatcaggct gataaaaatt atttataggc
    33841 aaaaaaatca cacgagctgt gtgattccat tatttgttaa aatacttttt agtttcagca
    33901 ataacgactg gcgacaagac caagagggca atcaagtttg gcagagccat caaggcgtta
    33961 acgatatctg cgataatcca gaccatatcc aactcgataa atcctcctaa caagaccatg
    34021 agcacaaaaa acacacggta gagccagata aagcgagccc caaagaggaa ctcaaaacag
    34081 cgttctccgt aatagttcca acctagaatc gttgtaaagg caaaaagtac aaggaagatg
    34141 gtcaagaggg caggcccaaa gtgtgaaaag actgttgaga aagctgactg agtcaaggca
    34201 accccattca agtcaccact ccaaactcca gttaccaaga tggtcaaacc agttagagta
    34261 caaatgatga gggtatcaat aaaggttcct gtcatggaaa tcaaaccttg ctctactggt
    34321 tcatttgtct tggcagctgc aataggagca gaacccagac cagattcgtt tgagaacaca
    34381 ccacgcgcca caccattttg aatagccatc cgaacgctag caccagcaaa tccacctacc
    34441 gcagcaaggg gactaaaagc tgaggtaaag actaaagcga ttgtgccagg gatttttccg
    34501 atattaaaga aaataactgt aagagttcct aagatataaa tgagggccat aaaaggaaca
    34561 acagtagttg aaaccttaga aatagacttg agtccaccaa agactgcaat cgctacaaag
    34621 acagacaaga cgagagctgt gatggctggc gaaatcgtcg ttgtattttg gatagattct
    34681 gtaatcgagt tgacttgggt gaaggttccg attcccaaga gagcaaccaa tactcctgct
    34741 actgcaaaca aaacagcaag tggtcgccac ttttctccca tccctagaag gatatagtgc
    34801 atgggacctc ccgctactgc accatggtcg tccttggtgc ggtatttgat ggccaagagt
    34861 ccttccgcat acttggtagc cattccaaag aaagccgcca tccacatcca aaatagagct
    34921 cctggtccac caaccttgat agccgtcgca actcctatga tatttcctgt tccaacagtt
    34981 gatgccaagg ctgtacacag agctgcaaaa ctggatacat caccatgtcc cttatcctgg
    35041 ataaaaataa gctgaaaggc cttgggcaga cgcaaaacct gcaagagtcc tagccgcatg
    35101 gttaggtaaa tccctgttcc gaccaataaa atcaagaggg gcggtcccca agcaaaagca
    35161 tcgattgatt taagcaattc taacatttcc ttctcctatc gtttcaaccc caaaagaaag
    35221 agcacatgca agatacatgt actctggaat gcttagataa atgctaaaaa gcggtctatc
    35281 ctagctctgt ccttttacct gagagtttga gcagttgcct gccttgcccc ttcggtgcct
    35341 ttacggtctc tccagagttc cgtccattta cagtcatgga aaatcaaacg attccccact
    35401 tctattaaac ttcattcggt gttggtattt aattgattct aattttacaa aaaatgttgg
    35461 cttttgtcaa tgtgtttatt agtaaaaatt agttcaacag tttttacttt ataaagtcca
    35521 gaatactgct atcctttaaa agtgacaata gtcgcaccac tgcctccagc attttgtggg
    35581 gcatagccga aactcttgac atgtttgttt ctttgcaagt atttggtaac tccttcacgg
    35641 atgactcctg ttccgatacc atggatgata tcaacttgag ccatattgtt aagcaaggct
    35701 tggtcgatga aggtatctag ctcattcatg gcttctacat agcgcttgcc tcgaagatcc
    35761 agtctagctt gaggtcctcg cccagaagtt cgtttcacaa cattgacctg tttcttcttg
    35821 actggttttt cttgctgggc ttgaacaaga tcaaactctt tctcttccaa ggtcatctta
    35881 atcaagccaa cttgggcttc ccagcgaccg tccttgagtt gactggtcaa ggtaccacgc
    35941 tgaccataac tgagaaccac gatatcatct cccacctttg gagctcgttt tttcttggcc
    36001 ttttgaagga ccttattttt agacaagtcc actttttcag gagccaattt tttcaacttg
    36061 accttggctt caatgatttc gtggggcttg agttgggatt tactgtggag atttttgaga
    36121 atctggtcac tttcacttaa ggccatatcc acaatctcag cagcctgttc acgcgccttg
    36181 ttaagctcgg tttccttttc acgattaagc tcgttgtaga gtttttttag cgcacggttc
    36241 atcttgagat tttcttgctc cacctcacgg atattgtcca aacgtttgcg gctttccagc
    36301 gtctgctctt ctaattgctc aatgatacga ttgacgtcat tgtcctgatc gatctgctga
    36361 ctggcatctc ctacgataac ttcagatagg cctagacgtt tggcaatttc aaaggcatta
    36421 cttcggccag gaacaccctg cataaagcga taggtcgggc gaagagttgc agtatcaaac
    36481 tccatactgg cattttgcac aaaggctgtc tcaataccgt aggccttgag ttctggatag
    36541 tgggtcgtcg ccatggtctt gatttgacgc aggcgaaggt cctccagaat agccatggca
    36601 agggctgctc cctcttgggg atcagtacca gcccccaact catccaaaag taagagtgaa
    36661 tgttggttga ccttgccaag aatatccacg atattggtca tatggctaga gaaggtagac
    36721 aagctctgct caatagactg ctcatctcca atatcagcaa agatttcttc aaaaatacca
    36781 acacgacttc ccttgtctgc taaaatcggc aatcctgact gggccatgac ctgtgtcaag
    36841 cccagagttt tgagcatgat ggtcttccca cctgtattgg gacctgtaat gacaatagct
    36901 gttaaatctt gaccaaaata gacatcattt gcgacggcat ttttgaccaa aggatggcag
    36961 acatggagca gttgaatctc ttgattttct gacagctgag gcacgactgc ttgtctttct
    37021 tggataaatc gaaccttggc acgaatcaag tccagatgac cgataatcca agcgtcatta
    37081 gcaatctcag ccgcatgagg gcggacacgc tcagaaattt cttggagaat gcgaagcatt
    37141 tcatagcgct catctgctcg cagactagca atttcttcgc tcagtttgac tacctcacgt
    37201 ggttcgatat agacggtgtt tccactagca gaaatatcat gaacgacacc tgcaatctta
    37261 ttgcggtagg tgtttttgac tggtaaaacc tgacggccat ttctgctagc aacaattcct
    37321 tccgtcaaca tctgcgcttt ttgcttgagc aagtcttgta aaacatcgcg tacctgactc
    37381 tcgctatcat gtatttttcg acggattcgc gccaattctt cactggcaaa attttcaatg
    37441 aaacccgcat cattaaaggc ctgaagattt ccttgtaatt gcggaaaatc atgtaatttc
    37501 tcaaaccaaa gggctaattc ttccaagctg acattttcca gattggcgta aaaactttga
    37561 agttctcggc tggtaagaag cacgcgtttc aagagtagga actcctcgat attgagatcc
    37621 gctcccatct ccaacctctt gcagactcct gcaatttcct tagttgagag aatagtaaaa
    37681 tgcggttgct cgacgaaaag agcctgcatt tctttcatct cagcaaaagc ctgtttgatt
    37741 ttatctgctt tggcagtcgg agccagctgt ctcaattgct ccaagccctg ctcggtcaac
    37801 aaatgaggct caaacaaggc cttgacctta tcgagctcta atgtttctaa tattttctta
    37861 ttcatcttta tttccttgtc tttgaatgtc taggtgtggt agctttttac attctgatag
    37921 attcgagtca aatctgtaaa caaagggcta ggaaaactcc tgcccttttt atccgattaa
    37981 atttgtcacc cagatttgtt tgagccaact ggttgttatc ggtatactct ggatgatgtg
    38041 ttttgcgacg atactctttt caagaggatt ttgtataact gccatgggga tggtcgccaa
    38101 gattgtcaag gccatttgca agacaaataa ggtcaccaac atggacaaga tacctgctga
    38161 aacttggaac aacttaccac ccagtttttt gctaggaatc aagtgtaaga gaagaccaag
    38221 caaacgacca atgctataga caatcccaaa tacaagcaag tagccgatac ctgcataaaa
    38281 gaccttatcc agctgaaaga gttgatccga tgggaaaaag aaagtcccct gaccttcctg
    38341 cgaatttgca taagggagca ataaatggaa ttgctctcca agccccttat aaaactggcc
    38401 agccataaaa gccgatgcca tggctgaaat caggtaataa acctgtaaga gcaggcctct
    38461 ccgatagccg atataaaatc cccaaaccaa gaccaataga agaaggaatg aaatcataag
    38521 gaatcctcaa tcttgctctg ttcttgctta caagtcacaa gcttgtgacg gagttcttct
    38581 agctcttgct ccttatcgtc aaattcaatc tcacggctga gctgagttga taaacagttg
    38641 actgccaaca aaagagcgat tgtttcatca tctgcgctag gcatttgttc tttaattgct
    38701 tggtattttt ctgtcgcaac cttagcgatt tcctccataa aaaggttatc atgttcgctt
    38761 gtcaaggtta acgatttttt cccgaatgta aatttgaatc gatttagatt tgccataaaa
    38821 ttcacctcac gatattatac caaaattcgc taattttgtc agtttttaca aattttactg
    38881 cttttgtggt acaatagaaa ctatggcaag tatcacactc acaccaagcg aaaaggatat
    38941 tcaggctttt cttgaacact atcaaaccag tctggctcct agcaagaatc cctatatccg
    39001 ctactttttg aaactacctc aagcaacggt ttctatctat acttctggaa aaatcttgct
    39061 tcagggtgaa ggggctgaaa aatacgccag tttctttgac tatcaagctg tagagcaaac
    39121 cagcggacaa aatcttcctt taattgggac agatgaggtg ggaaatggtt cctactttgg
    39181 tgggcttgca gttgtggctg cctttgtcac acctgaccag cacgactttt tacgaaaact
    39241 cggtgtgggg gattctaaga ctctgaccga ccaaaagatc cgtcagattg ctcctattct
    39301 caaggaaaaa atccagcacc aggcactcct tctctcaccc agcaagtaca acgaggtcat
    39361 cggagaccgc tacaatgctg tttcggttaa ggttgccctc cataatcagg ctatctatct
    39421 cctccttcaa aaaggtgttc agcctgagaa aattgtgatt gatgccttta ccagtgctaa
    39481 aaattatgac aagtacttgg cacaagaggc caatcgtttc agcaatccta tcagcttaga
    39541 agaaaaggct gagggcaaat acttggctgt cgcagtttct tctgtcattg cgcgtgatct
    39601 ctttctggaa aatcttgaaa atttgggacg agaactgggt tatcagcttc caagtggagc
    39661 tggaacggct tctgacaagg tggctagcca gattttgcaa gcctatggta tgcagggact
    39721 caacttctgc gccaaattgc actttaaaaa cactgaaaaa gcgaaaaaac gcttagaaag
    39781 gtaagttatg aattcactta aaaatttctt aaaagagtgg ggattgttcc tcctaattct
    39841 gtcattacta gctttaagtc gtatcttttt ttggagcaat gttcgcgtag aaggacattc
    39901 catggatccg accctagcgg atggcgaaat tctcttcgtt gttaagctcc tccctattga
    39961 ccgttttgat atcgtggtgg cccatgagga agatggcaat aaggacattg tcaaacgtgt
    40021 catcggaatg cctggcgata ccattcgtta cgaaaatgat aaactttaca tcaatgacaa
    40081 agaaacggac gagccttatc tagcagacta tatcaaacgc ttcaaggatg acaaactcca
    40141 aagcacttac tcaggcaagg gctttgaagg aaataaagga actttcttta gaagtatcgc
    40201 tcaaaaagcc caagccttca cagttgatgt caactacaac accaacttta gctttactgt
    40261 tccagaagga gaataccttc tcctcggaga tgaccgcttg gtttcgagcg acagccgcca
    40321 cgtaggtacc ttcaaagcaa aagatatcac aggggaagct aaattccgct tctggccaat
    40381 cacccgtatc ggaacatttt aagagaccta agaggccgag aatcacaaat ctcagcctct
    40441 tcttctatcg tgagaagtga ttgtttattg acaaatactc aatgaaaatc aaagaacaaa
    40501 ctaggaagct agccgtaggc tgcttaaaac agtggtttga ggttgtggat agaactgacg
    40561 aagtcagctc aaaatactgt tttgaggttg cagatggaag ctgacgtggt ttgaagatat
    40621 tttcgaagag tataaaataa aaacaatccc aactctcacc tattcatgca aaggaatttt
    40681 atggaagttt atttttcagg aaccattgaa cggattattt ttgaaaatcc cagcaatttt
    40741 tatcgcatcc tcctcctaga aatcgacgat acggacgcag aggattttga tgattttgaa
    40801 atcattgtca caggaaccat ggctgatgta attgagggcg aagactatac tttttggggg
    40861 caaattgtcc agcactccaa gtatggagaa caactgcaaa tcagtcgtta tgatcgcgca
    40921 aaaccaacta gtaagggatt ggtcaagtac ttttcaagta gccatttcaa ggggattggt
    40981 ctcaagacag ctcagaaaat cgtagatacc tatggcgaaa ataccattga tgaaattttg
    41041 caacacccag aaaagttaga aggcatcgca ggactctctg ccaaaaatcg cgaggctttc
    41101 gtctccactc tccgtctcaa ctacggaacg gagatggttt tggccaaact agccaactac
    41161 ggcattccca acaaactagc ctttcagatt caagactttt acaaggaaga aacccttgat
    41221 gtggttgaaa attatcccta ccagctggtt gaggatatca agggtttggg ctttacaatt
    41281 gctgaccaac tagctgagga actaggcatc gaaagtcagg ctcctgaacg cttccgcgcc
    41341 ggtctagttc acagtctttt tcaggcctgt atggaaacag gagacaccta tgttgaagca
    41401 cgggatttgc tggaacaaac ccttactctc cttgagtctt cccgtcccgt agaactagac
    41461 cccagccaag ttgcccaaga gctctcctac ctgatcgaag aagacaaggt tcagcagatt
    41521 gataccaaga tctttgacaa cagcctcttt ttcgctgagg aaggtatccg cagtcacttg
    41581 attcgtatcc ttgaaaaagg agaacagaag agacaagatt tagaaactat tcaaaagcat
    41641 atcactactg tcgagcaaga actggggatt gagtatgata acattcaaaa acaagctatt
    41701 tgtgacgcta tccagaacaa ggtctttatc ctgacaggtg ggcctggtac tggtaagaca
    41761 actgttatca atggaatcat cgctgtttat gcccttttag aaggacttga cttcaggaag
    41821 aaaagcaatc tgcccattct tcttgctgct ccaactggtc gagctgctcg tcgcatgaat
    41881 gaattgacag gtttgcctag cgcgaccata catcgccact tgggaatgac aggtgacgat
    41941 gataccagtc atctggaaga ttacctagat gctgacttta tcatcgtgga tgaattctct
    42001 atggtagata cttggctgac caatcaactc ttctccaata tctcttctaa cagtaagatc
    42061 ctcatcgtag gtgacagtga tcagctacct tctgtcagtc ctggacaggt tctagcggat
    42121 ctgcttcata ttcctttgat tcctcagact cgcttggaaa aaatttatcg acaaagcaaa
    42181 gaatcaacca tcgtcaccct agctagtcag attcgacagg gcatcttgcc agctgatttc
    42241 acccaaaaaa aagctgaccg ttcctacttt gaaattgcta gtggccatat tcctgccacc
    42301 attgaaaaaa tcttaggtgt cgccctcaga aatggtattc ctgcccgtga tatccaagtt
    42361 ctggctccta tgtaccgagg gacggcaggg attgatgcta tcaatcagct catgcaagac
    42421 ctgctcaatc ccccacaaaa agatcaactc agttttgaag ctcctcagtg ccactatcgt
    42481 aagagagaca aggtcattca tttggttaac gatgctgaaa tcaatgtctt taatggggat
    42541 ttaggagcta tcacagacct gattcctggt aaatacaccg aatcgaaaca agacgagatt
    42601 gtcattgatt ttgatggtaa tgaagtctct tacccccgta acgaatggta caagattcgc
    42661 ttggcctatg ccatgagtat tcataagtct cagggaagtg agttcccagt tgtcatccta
    42721 ccgattacta gtgctagccg acgtatgctg gagcgaaatc tcatctacac agccattaca
    42781 cgtgccaaaa gcaaactcat cttactaggc gaattacaag ccttcgacta tgctacccaa
    42841 cacatcggaa ctgcccgaaa aacctatctg attgaacgct tcagtgatct actggagaat
    42901 gttgaagaaa agcaacaagc tgtctctgaa acagtcacat caagtgcctc tgaacaatcc
    42961 tacatcctaa ccgaagaaaa ctgggacagc attccagcca tgattgggat tacagacaca
    43021 gacctcaaag agatttttgg aaaatagtac atcagaaaac ccaccaattc aggtgggttt
    43081 tctgtttatt aagattattt tactgttgct gtgcttgtga tcaattcaac agcttttttg
    43141 atagtgatat catgtttcaa catgtcagct gaaagcaagt tttgaacttg tgcaacttcc
    43201 atgttgtagt ctgctgccaa ttgctcaact tctttttgga tttcttcttc tgaagcatca
    43261 aatccttcag ctttggcaac tgcttcgata acaaggttag tcttagtacg tgactcagct
    43321 tctgcttggt attggttgtg aaggtcttct tgagtagttc cagtgatttg gaagtacatg
    43381 tcagggttga tcccttgacg ttgcaagttc ccaaggaatt catttactga acggtgaact
    43441 tcttcatgga tcatttcttc tggaagttct acgatttcag cgttttctac agctgtatca
    43501 attgctgcac cttcaactgc atctttgtaa gcttcttctt tagcagcagc caattctttg
    43561 cggtattttt ctttcaagtc agcaagtgtt tcaacttctt catcaatgtc ttttgcaagt
    43621 tcatcgtcaa gagctggaac ttctttagct tttacttcgt ggatagttgt cacgaattta
    43681 gcttctttac ctgcaaggtc ttctgcttgg tagtcttctg ggaatgttac gataacatca
    43741 acggtttcgc cagctgagtg acctaccaat tggtcttcga aaccagggat gaattgacct
    43801 gaaccaagtc caagtgagaa gttttcacct tttccaccgt caaattcaac accgtcgata
    43861 gaaccaacga agtcgatcac aacagtgtcg ccgttttcag cagcagcttc cttgataacc
    43921 aattcagcca gattgttgcg ttcgcgttcg atacgctctt caacatcagc gtcagttact
    43981 tctttttcta catcaactga tacttcaagg tttttgtagt cacccaattt tacttcaggt
    44041 tttgtaacga cttcagcagc gataacccag tcttgacctt tttccattga agttacgtca
    44101 atttttggtt gggcaaccac ttcaagacca gcttctttta cagctgcttc ataagcgttt
    44161 ggcaaaagag cgttcataac gtcttggtaa agtgattctt caccaaattt tttgtcgaag
    44221 ataggacgtg gaaggtgacc tttacggaaa cctggaacat taagagattt cttcactgac
    44281 ttgaagacac ggtccaattc tggtttgatt tggtcttgag agatagtgaa agtcaagaca
    44341 ccacggtttg tttctttgtt ttcaaatgat acagacattc tgtcatttct ccttaaaatt
    44401 ttttaaatac agtctattat aacattttct ataaataaaa tctagactaa tgcagccaat
    44461 tatagacaac aagccttttt cctaactaaa acactcataa agtatagaca attttagact
    44521 actttggata tcttttggtt agtcattttc caaaactaat ttatctaatt tttcagt
//
LOCUS       DBEJKC010000011        42768 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.011, whole genome shotgun sequence.
ACCESSION   DBEJKC010000011 DBEJKC010000000
VERSION     DBEJKC010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 42768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42768
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.011"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="ACL3G6_000601"
     CDS             complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="ACL3G6_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HGR0545181.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQNPQKS
                     ISEQTAYEIDEEVRSLLNKARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
     gene            complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="ACL3G6_000602"
     CDS             complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="ACL3G6_000602"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HGR0545182.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEVDYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="ACL3G6_000603"
     CDS             complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="ACL3G6_000603"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HGR0545183.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPKLEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKTQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3790..5058)
                     /locus_tag="ACL3G6_000604"
     CDS             complement(3790..5058)
                     /locus_tag="ACL3G6_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HGR0545184.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5051..5173)
                     /locus_tag="ACL3G6_000605"
     CDS             complement(5051..5173)
                     /locus_tag="ACL3G6_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0009 family protein"
                     /protein_id="HGR0545185.1"
                     /translation="MENLLDVIEQFLSLSDEKLEELTDKNQLLRLQEEKERKNA"
     gene            complement(5178..5546)
                     /locus_tag="ACL3G6_000606"
     CDS             complement(5178..5546)
                     /locus_tag="ACL3G6_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HGR0545186.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5539..5805)
                     /locus_tag="ACL3G6_000607"
     CDS             complement(5539..5805)
                     /locus_tag="ACL3G6_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HGR0545187.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5873..9382)
                     /gene="mfd"
                     /locus_tag="ACL3G6_000608"
     CDS             complement(5873..9382)
                     /gene="mfd"
                     /locus_tag="ACL3G6_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HGR0545188.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9383..9952)
                     /gene="pth"
                     /locus_tag="ACL3G6_000609"
     CDS             complement(9383..9952)
                     /gene="pth"
                     /locus_tag="ACL3G6_000609"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HGR0545189.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     KADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10023..11138)
                     /gene="ychF"
                     /locus_tag="ACL3G6_000610"
     CDS             complement(10023..11138)
                     /gene="ychF"
                     /locus_tag="ACL3G6_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HGR0545190.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLIESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYESEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11222..11416)
                     /locus_tag="ACL3G6_000611"
     CDS             complement(11222..11416)
                     /locus_tag="ACL3G6_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HGR0545191.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11481..12617)
                     /gene="dnaN"
                     /locus_tag="ACL3G6_000612"
     CDS             complement(11481..12617)
                     /gene="dnaN"
                     /locus_tag="ACL3G6_000612"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HGR0545192.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12776..14137)
                     /gene="dnaA"
                     /locus_tag="ACL3G6_000613"
     CDS             complement(12776..14137)
                     /gene="dnaA"
                     /locus_tag="ACL3G6_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HGR0545193.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14350..15108)
                     /locus_tag="ACL3G6_000614"
     CDS             complement(14350..15108)
                     /locus_tag="ACL3G6_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HGR0545194.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNYFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15166..16347)
                     /locus_tag="ACL3G6_000615"
     CDS             complement(15166..16347)
                     /locus_tag="ACL3G6_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HGR0545195.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16530..17009
                     /gene="rlmH"
                     /locus_tag="ACL3G6_000616"
     CDS             16530..17009
                     /gene="rlmH"
                     /locus_tag="ACL3G6_000616"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HGR0545196.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEELSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17053..17126
                     /locus_tag="ACL3G6_000617"
     tRNA            17053..17126
                     /locus_tag="ACL3G6_000617"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17087..17089,aa:Arg,seq:tct)
     gene            17292..17417
                     /gene="comC"
                     /locus_tag="ACL3G6_000618"
     CDS             17292..17417
                     /gene="comC"
                     /locus_tag="ACL3G6_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HGR0545197.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17438..18763
                     /gene="comD"
                     /locus_tag="ACL3G6_000619"
     CDS             17438..18763
                     /gene="comD"
                     /locus_tag="ACL3G6_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system sensor histidine kinase ComD"
                     /protein_id="HGR0545198.1"
                     /translation="MDLFGFGTVIVHFLIISHNYHLICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIATFLFPLGLYSYFRWIKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFS
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18760..19512
                     /gene="comE"
                     /locus_tag="ACL3G6_000620"
     CDS             18760..19512
                     /gene="comE"
                     /locus_tag="ACL3G6_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system response regulator
                     transcription factor ComE"
                     /protein_id="HGR0545199.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19564..19635
                     /locus_tag="ACL3G6_000621"
     tRNA            19564..19635
                     /locus_tag="ACL3G6_000621"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19597..19599,aa:Glu,seq:ttc)
     gene            19641..19714
                     /locus_tag="ACL3G6_000622"
     tRNA            19641..19714
                     /locus_tag="ACL3G6_000622"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19675..19677,aa:Asn,seq:gtt)
     gene            complement(19755..20297)
                     /locus_tag="ACL3G6_000623"
     CDS             complement(19755..20297)
                     /locus_tag="ACL3G6_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGR0545200.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20425..22074
                     /locus_tag="ACL3G6_000624"
                     /pseudo
     CDS             20425..22074
                     /locus_tag="ACL3G6_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            complement(22104..24656)
                     /locus_tag="ACL3G6_000625"
     CDS             complement(22104..24656)
                     /locus_tag="ACL3G6_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HGR0545201.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAIYLTTLLKFGLIGLSTFFSLNKLFQSIPQALKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISITSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTYKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24718..26340)
                     /locus_tag="ACL3G6_000626"
     CDS             complement(24718..26340)
                     /locus_tag="ACL3G6_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0545202.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26546..27571
                     /gene="trpS"
                     /locus_tag="ACL3G6_000627"
     CDS             26546..27571
                     /gene="trpS"
                     /locus_tag="ACL3G6_000627"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HGR0545203.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27723..29201
                     /gene="guaB"
                     /locus_tag="ACL3G6_000628"
     CDS             27723..29201
                     /gene="guaB"
                     /locus_tag="ACL3G6_000628"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HGR0545204.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSINEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29252..30349)
                     /gene="recF"
                     /locus_tag="ACL3G6_000629"
     CDS             complement(29252..30349)
                     /gene="recF"
                     /locus_tag="ACL3G6_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HGR0545205.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSKSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(30352..30720)
                     /gene="yaaA"
                     /locus_tag="ACL3G6_000630"
     CDS             complement(30352..30720)
                     /gene="yaaA"
                     /locus_tag="ACL3G6_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HGR0545206.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            30879..32129
                     /locus_tag="ACL3G6_000631"
     CDS             30879..32129
                     /locus_tag="ACL3G6_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGR0545207.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32126..33409
                     /locus_tag="ACL3G6_000632"
     CDS             32126..33409
                     /locus_tag="ACL3G6_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGR0545208.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33451..34272
                     /gene="rodZ"
                     /locus_tag="ACL3G6_000633"
     CDS             33451..34272
                     /gene="rodZ"
                     /locus_tag="ACL3G6_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HGR0545209.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34283..34828
                     /gene="pgsA"
                     /locus_tag="ACL3G6_000634"
     CDS             34283..34828
                     /gene="pgsA"
                     /locus_tag="ACL3G6_000634"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HGR0545210.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34825..35652
                     /locus_tag="ACL3G6_000635"
     CDS             34825..35652
                     /locus_tag="ACL3G6_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HGR0545211.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35637..36476
                     /locus_tag="ACL3G6_000636"
     CDS             35637..36476
                     /locus_tag="ACL3G6_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HGR0545212.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36469..37263
                     /locus_tag="ACL3G6_000637"
     CDS             36469..37263
                     /locus_tag="ACL3G6_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR0545213.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37322..38140
                     /gene="mreC"
                     /locus_tag="ACL3G6_000638"
     CDS             37322..38140
                     /gene="mreC"
                     /locus_tag="ACL3G6_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HGR0545214.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38140..38634
                     /gene="mreD"
                     /locus_tag="ACL3G6_000639"
     CDS             38140..38634
                     /gene="mreD"
                     /locus_tag="ACL3G6_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HGR0545215.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38728..39906
                     /gene="pcsB"
                     /locus_tag="ACL3G6_000640"
     CDS             38728..39906
                     /gene="pcsB"
                     /locus_tag="ACL3G6_000640"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan hydrolase PcsB"
                     /protein_id="HGR0545216.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40130..40909
                     /gene="rpsB"
                     /locus_tag="ACL3G6_000641"
     CDS             40130..40909
                     /gene="rpsB"
                     /locus_tag="ACL3G6_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HGR0545217.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGHQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            40988..42028
                     /gene="tsf"
                     /locus_tag="ACL3G6_000642"
     CDS             40988..42028
                     /gene="tsf"
                     /locus_tag="ACL3G6_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HGR0545218.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEDGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            42343..42597
                     /gene="tnpB"
                     /locus_tag="ACL3G6_000643"
     CDS             42343..42597
                     /gene="tnpB"
                     /locus_tag="ACL3G6_000643"
                     /inference="COORDINATES: protein motif:HMM:NF017528.4"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR0545219.1"
                     /translation="MDSLAYVVKTHFELDSFSGQVFLFCGGRKDRFKALYWDGQGFWL
                     LYKRFENGKLTWLSTEKDVKALAPEQVDWLMKGFSITPKI"
BASE COUNT        13403 a         7361 c         7879 g        14125 t
ORIGIN      
        1 tttcgtcatt catttttgac tttacttcat cataggatag tgcatgagat tcctcttcta
       61 ctgcttcagg catctttcct gtttcgtaaa gagctttaat ttgtgtacta tccaatgttt
      121 cgtatttcaa taatgcttct gcaattaact tgtgagtttc acgatttgac tgaataattt
      181 cagcagcttt atttcgtgcc ttatttaata atgaacgaac ctcttcatca atttcataag
      241 ctgtttgttc tgaaattgat ttttgaggat tctgtgcacc aaacatagca tggtttcctt
      301 catattgtac tgggccaagt ttttcactca taccgtactc tgtaaccatt gcacgtgcca
      361 tttgtgtcgc ttgttcaaag tcgtttgaag ctcctgtagt ttggacatta aagataattt
      421 cttcagctac acgtccaccc attaagccag ccaattgctc tttcatatct tctttagata
      481 gaagcatttg atcctcttta ggaagtgcaa tcatgtatcc gcctgcacgg ccgcgtggta
      541 caattgtaac cttatggaca acgcgagcat tcgacaagac tagaccaaca atggtatgtc
      601 ctgcctcatg gtaagcaacc aattctcgtt ctttttgtga aactgtctta tctttcttag
      661 aaggtccagc aataactcta tcttctgctt catcaatatc tgaagcatca attatcgatt
      721 tattgcgacg agcagcaact aaagctgctt cattcaagac attctctaaa tcagcaccaa
      781 caaagcctgg agtttgttga gccactaatt tcaaatcaac atcttctgct aaaggcttgt
      841 tcttagcgtg aactttcaag attgcttcac gacctttaac atcaggacgg ccaaccaata
      901 cttttctatc aaaacgtcct ggacgcaaaa gggcaggatc aagtacatct gaacggtttg
      961 tcgcagcgat gacgataatc ccttcatttc cctcaaaacc atccatctca atcaaaagtt
     1021 ggttcaaggt ttgttcacgt tcgtcattac ctccgccgag accaactcca cgttgacgtc
     1081 caacagcatc aatttcatcg ataaagatga tagctggtgc tgcttttttg gcatcctcaa
     1141 aaagagagcg aacacgacta gctccaactc cgacaaacat ttctacaaag tcagaacctg
     1201 agatactaaa gaatggaaca cctgcttctc cagcgactgc cttagcaagc aaagtcttac
     1261 ctgtccccgg aggtccctcc aaaagaacac ctgctggaat acgggctcca agttttgtga
     1321 atcgttttgg atcttttaag aactcaacaa cttcaactag ttcttgtttt tcttcctcag
     1381 ctccagcaac atctgaaaat cttactttaa tatcttcttt atttgctgct ttagccttac
     1441 tacgtccaaa actcattgga ttacggccat tgcctcctcc catatttccc atcatagaga
     1501 ataggaagaa gaatagaatt ccaaatggca caatggatac gagtagatta atccatatac
     1561 cacttgaact ttcatgctta acagttactt ctgctttatg gtcagtagca agtttttgca
     1621 attctgatac ggtagtatct gcaggaagaa tagtgctggt aaatttctct accttagtaa
     1681 cagatggcgt gaaaaactga atacctgttc cttctttact tgttttagga tttttataga
     1741 caccagaaac ttcgataaca ctaccatttg gttggtaagt taattctttt acattaccat
     1801 cggtaatttc ttgtaccaac tcagtatagt tgatttgctg acttcctcct gagttattcc
     1861 cagaatagaa atactggaat cctgtcacaa ggaaaaagat aaataataac catagaaaag
     1921 gatttttaat taaaccatta ttttgttttt tcattaaaga ttattctttc taatttgaat
     1981 acacttcctc tttcaatact ccaatataag gaagattacg ataattttct ttgtagtcta
     2041 aaccataacc tactacaaac tcatttggga tagtaaagca ggtatagtct acctcaattt
     2101 ctacaacacg tccttctggt ttatccaaca aggttgcaat tttaacagaa gctgcttctc
     2161 tttctttaaa catatctcgc aaattcttca aagtttgacc tgtatcaatg atatcttcta
     2221 caaatagaac atgtcttcct ttgatatctt gagtcacatc ttgtttaata ttgataacac
     2281 cactacttgc tgttccacca tggtagctag aaaccatcat gaagtccatt tcaatatgtg
     2341 tatcaatatg tttgaccaat tcagccataa aaggaataga tccttttaaa atcccaacta
     2401 agattggatt ttttcctgca tagtctttag ttaattgagc acctagtttt ttagctgctt
     2461 ctgtaatttc atcgtgtgaa acgaggactt ttttaatatc gttttctaac attttttacc
     2521 tatctatttt ttctatataa agtacagtgt tcattatatc atttttcgtt tttttactca
     2581 aattattggt cgcaattccc aaaattgaga caatttcacc aaattgctca ataataagag
     2641 cagagtttct cttttccata gggattttca aatcaataaa taaacgtctg agtttttttc
     2701 tatgcccatt ttgaatcaaa acatctcctg tttttcgatg acgaatgtgt atggatgttt
     2761 cacgtgaaac aggtatttgt tgaattaatt caccttctaa tggaagtcca aaggaaaata
     2821 aatatccttg ataagctacc tgattttgat agtgtaacac aagttcatct tccttttcat
     2881 cagcctgcgg actgatttta caaatctgaa actgttggta ctcttttatc aattcatagc
     2941 catttttaat cggatgacga tactggcttt tagattttaa aatctgctga acttcagcaa
     3001 actgagtttt tgtaagattc aaatctggaa aacgattcag ataagtttga agtaaaactc
     3061 tttgtgtaga ctcagagtaa gaaaataact gctgtaaatc ttccacatta atattgttag
     3121 ataattcagc tattgccaaa tcataatcta aaatttcatt gccaatgcct aagattgcat
     3181 ccctaaatcg aggattttct ttttccaatt ttggtaagta agaatttcga atacgatttc
     3241 gaaaataatg attctcctga tttgatgtat cttcaaagtg aaaaattgat ggaaagtctt
     3301 ttttctgaaa atgcaagaag ggacgaatga tttctatctc tccgactact tgcttctcct
     3361 taattcctga tagatagcgc aagcgagttc ctcgaatcaa gcgcatcaaa atcgtttcca
     3421 cctgatcatc agcatggtgg gcagtgacta aagctgtcgc acctgtcttt ttcatgacct
     3481 cttgaaaaaa atcataacga aaatttcgtg cacgcgcttc tgaaaattct cctgaaaaat
     3541 tgctgatata aataggaagc tctgcttcag cagccaactt ccttaattcc ttttcttccc
     3601 aatctgattc aattctctgc ttatgattca catgagccag aatcaattca atctctaact
     3661 ctttttgata agtagacaat accttaaata gaaacataga atctaatcca ccagaaagag
     3721 ctagaaccgc cttagcatgc tttttgaaat atcccttctt gagaaaatga tttaaaaaat
     3781 ctggttccct cattttagaa cctcataaac atccttggct atcttagaaa tcgtatcata
     3841 atcagaattc ttagtgaaaa tagaaagaat aaatggagaa tctgcataga caacacccgt
     3901 atcatgctta aattcatccg catctccaat tttatgagct actttaacag aaacaccttt
     3961 ggcaattcgc tgactatcaa aatctgtttt agtcaaagac tctagcacaa atccattttg
     4021 attataaata gcttccataa acttcccggc catcttagaa gaaatcaatt tttcttttgg
     4081 atcccaatca tctcccataa tggcagacat cttggatttg aatgtggcat cagattggtt
     4141 tgaaatgtaa tatcccaata gattatgagc tacattatca gattcttttg atactttcgt
     4201 aattaaatcc tttaaagaat attctttatt atcttctttt ttaggaagac taccacttcc
     4261 ctctggttta taagaacctg gaaaatcatt gactgcagat acgtatttta cagtcgtatc
     4321 taactgataa agaccctcat ttattttttc ttgcgtataa tagagatagg agagtttcaa
     4381 aacgctggct gcatacatct tttcatcttg attgatacca gcttcttttc cagtagtcag
     4441 ttgcttaaca taaatagaga aagaatcttt ctgatatttt tcagataaca tttcttgaac
     4501 tttactcatc cgattatctt cttcagaagt tgattcttta gctacccatc cagcctgatc
     4561 aatatgtaga aattctcttc cttctacaaa catggtcttg tcgattgata cttgcgaata
     4621 agctgataag gatgatttca cttcttttaa atcataagga ctattgtaca gtttaaagtc
     4681 agattctaac catgcttttt ttattgttgg agttacctct gattgatcat ataaaaatcg
     4741 tttgtccgca gctataaatt gatgatttga tagcttaaat actggaattc cttgtttatt
     4801 taagcgccac tcggttattt gaaaacttgt tttgggagtc aatttcccag attccactac
     4861 taaatcttca ttcgcataaa caggaacctc tccataaacc atgggagaac ttaatttttc
     4921 tctaaaataa ataccaaagt cagattgtga aaggtaataa atttctttcg aagtatagac
     4981 gacttctttt tctgtgctaa cgacttttga aatggtcaaa aaacttggta gcaacaaaat
     5041 aattaagaat ttacgcattc ttcctttcct tttcttcttg taaacgcaat aattgatttt
     5101 tatcagtcaa ttcttccagc ttttcatctg acaaactcaa aaattgctct attacgtcta
     5161 ataaattttc cattttatca cctttgaagc aagtcaggaa tcgtataaac tttttccctc
     5221 gacttagaat aatagtactt cgctcgtgta tatttagcag cataatcttc atctttcaac
     5281 ttggtagcaa atgctgtttc cttatccttt tcatcactca aagtttgata ctgagtttgc
     5341 aagtctgcta attgctgacg tctttggagt aattgctgat aactctgcgc caaattaaaa
     5401 gttggcaaga taaataatag cataatcaaa atcaataccc cccccataaa acgattccgt
     5461 ttttgtcgtt ctttcatcag gtagcgacga cgttggtatt cattttgaat aaaagaatta
     5521 ttcaattgta caatattttt agacattttc ttctacccgt gtttcactga taatttcata
     5581 cattcctgct gcatcttctt tttttgtact atctttcatc tctagtactt ttacaagcag
     5641 caacttattg ccaaagcgaa tttcaacttg gtcattaact ttcaagtccg ttgaactttt
     5701 ggccaagatt ccattaacct tgattctacc tttatctgct acttcctttg cgactgtacg
     5761 acgcttgata attcgcgata cttttaaata tttatctaat ctcatcctta ttacctcaat
     5821 ttattattgt accattttta tctattttta tctattttat agaagaaaaa tatcaaatgg
     5881 aattttcttc cttaaactct tttatctcta ataaactttc tccaaaaatc agcagacctt
     5941 ctaaaatttc ataatctttc ttattttgga catcaaatac aagctccatt aatcccttat
     6001 tctcagcgat gcctgctttt aagttcgtta cggataaagc tttaaaataa tcttgagcta
     6061 aaaacagtcg ttgagtgact ttttcaaatt gaattgtaat tttattatct tttctttcca
     6121 cacgttgaac aaagaccttg tccaagtatg atttgaccaa accaatctct aaaagatagg
     6181 ctactacatc tgggtattct ccaaaacggt ctatcaactc ctcttgtaac tcttcataat
     6241 tgacacggtt gtcaatttga cgaattttct tgtaaatttc aatcttatgt cgttgatcag
     6301 aaatataagt atcaggaaga taggcatcaa tttgcaaaat caactcagca ttccctttgg
     6361 ttcttgtgtt agcgttagca ttaccgtttc gtttagcaat agcttcctct aataactgcg
     6421 aatacaattc aaaaccaaca gaatcaatga aaccagactg ggattttcct aaaagatttc
     6481 ctgctccacg aatcgaaaga tctcgcattg caatcttaaa gccagagccc aattctgtaa
     6541 atcctttaat cgcttctaat ctcttttcag agacttcact gattgatttt tctggacgat
     6601 acatgagata agcataagca atacgattac tacgaccgac tcttcctctt aactgatata
     6661 aggttgacaa gcccatatgg tccgcatttt caataaataa agtattagca tttggaatgt
     6721 ccacccctgt ctcaataata gtagtcgtca ccaagatatc gtattgtccc tcaataaagt
     6781 ctaatagagt attttccaac tggacttcac tcattcgacc atgaacatat ccaatcgaag
     6841 cctccggaat caactcctgt aattctgaaa ccttctgaac aattgtgtca actttgttgt
     6901 aaagatagta aacttgacct ccacgctcca tttcacgcaa gacagcatca cgaatgacac
     6961 tatcattctt ttccaaaaca taggtctgaa caggatagcg attagtcggc ggagtttcaa
     7021 taacagacaa atctctgatt cccagcatag acatatggag ggtacgaggg attggcgtag
     7081 cggtcaaggt taggacatcc acttgtttct tcagttcttt caaagtttcc ttatgcttga
     7141 caccaaatcg ctgttcctca tcaataatca tcaagcccaa atcagcaaac acaacatctt
     7201 ttgacaaaac acgatgtgtt ccaatcaaaa tatcgacttg accgtttttc aatttttcaa
     7261 gtgttgcagt ctgctctttt ttacttctaa agcgactcaa cacatcaaca ttaactgcaa
     7321 aattttggaa tcgttcctta aaattcgtat agtgctgttg cgctaaaacc gtcgtcggaa
     7381 ctagaatgac aacctgtttg tgatcattga ctgctttaaa ggctgcacgc atagcaactt
     7441 cagtctttcc aaaaccaaca tccccaacta aaagtcgatc cattggctga gaagcctgca
     7501 tatccctttt gatttcctca atactacgaa gttgatcatc cgtttcaaca taagggaaag
     7561 catcatcaaa ggcatcttga tcatcatcat cagctgagaa agcaaaaccc ttcaactgac
     7621 tacgttcaga gtagagtttg attaaatcat cagctatatc ctctacctgg ttcttaacct
     7681 tttgcttggc ctttttaaaa tgaccgtcat ttaatttatt gagttttgga gctttaccat
     7741 cacttgaaat atatttggac agtagatgaa tctgttccac ggggatagaa atttgatcac
     7801 cattttggta ttggacactg acataatcgc gatgaattcc cttgatttca atggtttcaa
     7861 ttcctagata ttgaccaatc ccatggatat gatggacaac atagtcccct ttttcaagtt
     7921 cattgtaatc ttttaatctc tctgcatttg aaacatgttg tcttcgaaaa cgacgcttta
     7981 atttcttttg aaaaatctca tgttcagtta tcaataaaat cttttcatct acaaaatgaa
     8041 aaccatgtct gagattaccc tctattaagt ttacagattc tttacagata tttgtcttat
     8101 ctctagaatc caatttaatc tgatattcct ctaacatatc ctccaatgtt ttacttccca
     8161 ttgaattgct agactgcaga ataatggtgt aatccatttt tttatatcgt tcaatttctt
     8221 cttttagaaa agaaaactga ttgaaaaatt cctgcatagg atattgattg aattgataaa
     8281 ttttgtcaaa tttgagattt cctaaaccct tttgaagatt agagaaaaag gtcactggac
     8341 tttgtttttt atagatttgt tcaatatcag aaaaatactg catatcagaa aatgctttac
     8401 tattctgtaa ttcttctgta aagtactgcg ctaagtctct ttcaaagact tcatactgat
     8461 tcatcaattt ttgataatca tcaaagaata ttggagtatc tttttcaata taatcaaaga
     8521 cagtccatgt cttatcatag cacaaagata aaaacttccg agagtctgca tgactttgtt
     8581 tttggtgaaa acttgaaaga atttcttcta ggtatgattt caaaataggt gataaagttt
     8641 ttgaaatttg tttttctaaa gctgactgtc ctcgttgata atccttttct ctcaaaagca
     8701 tatcactagc tggaaagata gtgagttctg tcttattttc tttcgataat tgtgtttcta
     8761 cttcaaatga cctgatacca tcaatttcat caccaaaaaa ctcaattcga caaggttcta
     8821 actgggatat ttcaaaaata tctaaaatat ctcctcgaag actaaattcg ccctgagttt
     8881 gtacttgagt aacttttcga tagccatttt cctttaactg atggataaac gcgtgttgat
     8941 catattcttc accaactgag atttttacaa tactatcttt gaatgcattg ggagacggta
     9001 aaatcaatcg acttgctgcg atattacaaa ctaaaatccc tttcttagat gaatcagtca
     9061 aaaaacgcaa ggcttcaacc cgtgaaataa ttttttcctg tgaagacatc aaaaactcca
     9121 ccataggagc atcatctacc aaaaatggat agacgagttc ctcacccaag atagatataa
     9181 gatcactaac aagtccttct gcttctccat aagttgacgt caataacaca atcctatctt
     9241 ctttttctaa actgcttgca attgcaagag ccttagtaga tgttgataaa ccaagtatta
     9301 gttgtctttt cttatcagtt aaattttgat gccatttttt aatctgatca ttttctgaga
     9361 ataaatctaa taaggtcacc atttatccgt tatacctctg cattgttttc tcaaaatttt
     9421 tctcttgtaa atagtagttt acagaatcgt caactttgtc aacagactgt aaaataccga
     9481 tataatcatc cctgtcaaac ttactcaaaa catgatgaac aactgacata ccatttttag
     9541 gtcttccaat tccaatctta acacggttaa agacctgagt tcctatatgt tgaataatag
     9601 acttgatacc attatgacca cctgctgagc cttttgctct taaacgaatt ttcccaactt
     9661 ccatgtcaag atcatcgtaa atgataagta aatcgtcaat atccaaacca tagtaagtta
     9721 ataaagcatg aactgctttt ccactttcat tcataaaggt cgttggttta accagataaa
     9781 ttttttctcc atttaggaaa aaggatgcta ggtcagcttt aaatatctta tcgtgtgtaa
     9841 aagtgacatt ctgtttcttc gctagttgat caatcaacat aaaaccaaca ttgtgttttg
     9901 tttcaaaata tttatcccct ggatttccca agcctacaag taatttggtc atttattttt
     9961 cctttcaaaa gccaaaaggg ttggaatttt tttccaacct aattgacacc atttattaat
    10021 ttttagacat taaagcggaa ttccatgata tcgccatctt gaacgatata ttcttttcct
    10081 tcttcacgca agcgtccagc ttcttttacg gccttttcag attcgtattt cactagatcc
    10141 tcatatgaca tggttactgc acgaataaag cctttttcaa agtctgagtg gataatacca
    10201 gctgcttgag gagccttcat accacgtttg aaagtccaag cgcgaacttc tttttcacca
    10261 gctgtgaagt aagttcccaa tccaagcaag tggtaagctg cacgcgtcaa cttatctaca
    10321 cctgattcta tcaaaccaat ggcttcaaga aactcttttt tatcttcatc atccaattca
    10381 gaaatttctt cctcagcacg cgcagaaata acgactactt cagcattttc tgtcgctgca
    10441 aattcacgaa tttgtttgac atagtcgata gagtcaggtt ctgaaaccac atcctcgtcc
    10501 acattagcta cataaagaac tggtttagtc gtcaaaagga aaagaccttt gacaaccttt
    10561 tgttcctcat ctgtaaattc aatggtacga gctgatttcc cgtcttctag gactggttta
    10621 atcttttgaa gaacattgaa ttctgctact gattctttat ctttttgcgt acgtgccatc
    10681 ttttctacac gcgcatatcg tttattgact gattctaagt ctgcaagaat caattctagg
    10741 ttaatggtgt caatatctgc aagtggatcc acaaaggcgt cttcacgtcc ttgctcgcgc
    10801 atcacatttt catcatcaaa agcacgaact acgtgaacaa tcgcatctac ttcacgaata
    10861 ttggccaaga atttattccc tagcccttct ccttttgaag ctccttttac aatccctgca
    10921 atatccgtaa attcaaatgt tgtgggaact gtctttttag gagttatcat ttcagttagt
    10981 ttttgtaggc gttcatctgg aacttccacc attccaacat ttggatcaat agtcgcaaat
    11041 gggtagtttg ctgcctctgc tcctgctttt gtaattgcat taaatagtgt tgatttacca
    11101 acgtttggca aaccaacgat acctgctgtc aaagccatat ttctcattct ccgttttcat
    11161 ttcaatccct aatattataa cacaaaaagg gataaagtgc taaccctcta actaagggtt
    11221 ctcagtcaat aattttattc atttttcgct caaaatcata tcgccccatc atgacaacat
    11281 gctcacaatt actgcatttt attttgatat ctgctcctac acgtgtaatt tcccaacgat
    11341 tagccttttt accagtcgac ttgattgtac aagcgtgtga ttttttcatc tcaacaaaat
    11401 ttccaacttg atacatacta ctctcctttt ctttttcgat tatatcataa aagaggcgag
    11461 ccaggctcaa cctctttcac ttaatttgta cgaactggtg taatgagctg catgaagtct
    11521 tcgtcagtat ctgctggcac aagagtaaat ggacgaacag ctgagataaa gctaatagtc
    11581 accttttcgc tatttaaagc tttaagagaa tcaatcaagt aagttgggtt gaaactaatg
    11641 gtcaaatctt caccagtaac ctgatcagta tcgatttctt cgtttacttt accaacttct
    11701 ggagagtgaa catgggcgct aacaacccca tccttaattt caagtttcac agtaccattt
    11761 tgagtcgcac ttgataaaag acgggcacgc tccattgact ggcgtaagtt taccacatta
    11821 aaagtaatag tagtgttaaa gtctgttgga atcaagcgat ctgtatcagg atagtttcct
    11881 tctaggagac gagtatagaa gctaatattt tcgcttctaa agaggatttg attattggca
    11941 aagaaaatct ctacagtttc gatatcatct gtaaataccg ctgaaaattc gcgtagagaa
    12001 cggctaggaa ttacgacatc aaaatcatca ctattttttt caagagtcaa ttttttctgg
    12061 cttaggcgat gagagtctgt tgcaactgtt tttaactctt tgtgttgact caatacgaag
    12121 tggacacctg ttaaaatcgg acgactctct tgtgtacttg cagcaaaggc tgtttcatta
    12181 ataattttct tgagtaattt tgtttcaagt attaaaggag tgcttgctga aatttcttgg
    12241 attcgtggat attgttcgct atcttttcct tttagggtaa tttctgattt gccactggtt
    12301 aaaacaattt gattttgttc aatttcttta aaatcaagag ttacatcagg taaactagat
    12361 actacattga taaagaaaga agcttcaaga aggatcgaac ctaaagaagt aattaacaaa
    12421 ccagcatctt catttttttg agaaataaaa ttttcaattg aaatttgacc atttgaacca
    12481 attaaagtaa taccttcatt ggtcacgtca atttttactg ttgataaaat aggaatggca
    12541 tttttagaac taatagctct cttagtagta tttaatgctt gtagaaataa atttttatta
    12601 attgaaaaat gaatcatgga ttctccttta tttattttta gtattagaaa gataatagta
    12661 ataatagagt ctgtgaaatc tgtggaaaac agcctttaaa caagtcatat caagtttttt
    12721 agcttgttta aaaaatgtgg ataaaaaaga taaaaaacta aaagttatcc acaaattatt
    12781 tgattttctt tttgattgat tcaatttcta aacgtaaatt atcgtcttga tcaatcaaag
    12841 attttatttt ggcatgggca tgaatgactg tggtatgatc ttttccccca aattccttcc
    12901 caatttttgg aagactatta tctgttagtt ctctagataa atacatggct acttgacggg
    12961 ccaaaacaat attttgaagg cgtctacttc ccttcatttc tttgatacta acaccataaa
    13021 agttaccaac ttcagtttgg attttatcaa ttgggatgac gagcatttgg ctaacatctt
    13081 gtttgcgggc tctaatggct tctgcagcaa tatcaatagt gatatccttg atttttttta
    13141 ctctggcaat taaagtgatg tcgttgatgg ctccctcaag atctcgaaca tttgaatcaa
    13201 attgcccagc taggtattct agagtatcac tttggaaatt gtagcctaaa tgttccgttt
    13261 tactttgtaa aatggcaata cgtgtttcaa agtcaggggg tgtgatagtt tgtgtcaatc
    13321 cccaactaaa acgcgtgaca agcctctcct cgagcccttc tagatgtttt ggactacgat
    13381 cactcgttag gacaatctgt ttttgcttgt catgaagggc gttaaaggta ttgaaaaatt
    13441 cttcctgagt tgcgactttt tttccgctga gtgactggat atcatcgatt aacaaaagat
    13501 caagactacg ataggtcttt ttaaactttt ccatttcccc aagtcttagg tgatcaagaa
    13561 agtcattaat aaagctttcg gcagggatat atttaacacg cgcattagga atatttttta
    13621 gaatttcatt tccaatagcg tttaataagt gagtcttacc aaggcctggt cctccataga
    13681 taaaaagagg gttataggtc agagccaaat cttcagagac agctaaagcg gctgatacag
    13741 cccaaacatt tccatcccct tgaataaagt tatcaaaggt atacttttct tttaatcccg
    13801 tatctgaata aggaatagat actaactttg gactatagtc ataaagagtt aaatttgtag
    13861 cttcttcaac ttgtgagcta gtcgtatctt gaggtttggt gaaaatatag tggggagtta
    13921 tttcagcgtc ataaatttca aaaccagcta ctacaataat atcttttagt tgtttttccc
    13981 agaccatttc catttcagag cgaggtagaa atatagtggc aacattttcc tctaccttga
    14041 tgagttcagc ttgaatagca tagaaatcat acatggatcg agtcagtctt tcttgtgcaa
    14101 attctaatat acgattccaa aattgttttt ctttcaatcc tttctcctcc tttactattt
    14161 aaaagtttaa tactagagat attttaccat agatagcaag aattttccac aagctgtgaa
    14221 aaataatcca caatgttact aaactttatc cacaggttgg ggataaaaga agaaattatt
    14281 gatttattaa gctttttatc gaaaaacata gtggataacc ttgtgagata aaaaaataaa
    14341 agaacagcct tatttcaggc tgttgataat tctactatat tcttcttgat ttgaaaaaga
    14401 aataatgatt tttccactgt cttttttaga tagtttaatt tctacatcta atccgagtag
    14461 ttttcttaac tgtttttctt cattttgtat gaaataatta gttttttgct gtttcttttg
    14521 ttttttctct gtcagaagag cttctaactt ccttacagaa atatcttctt ctataatccg
    14581 ttgaaagaaa tagtcttgtt gttccttatt taacccaact agggaacgcg catgggcttg
    14641 tgatagtttg ccattttcta cttctgagag aatctgttct ggcaaggaaa gtaaacgaat
    14701 ggagttgctg atatatggac gagacttgcc catcttatct gcaatttcag catgggtgaa
    14761 tcctttctct acgagagatt cataggcgcg tgcttcttct attgggttta aattttctct
    14821 ctgtaaattt tcaataatgg actggaccat catctcttgg tctgaaatct gtttaacaac
    14881 agctgggata gaccgtagac cagctaaaag tgaagcccga tagcgtctct ctcctgcaag
    14941 gatttcataa ccaataacag gagattgacg aacaataatc ggttgaatga ccccattttc
    15001 tttgatagac tgtgctagtt catctagttt ttctctatca aattcttttc ggggttgata
    15061 gggatttttt tgtatatctg tgatagaaat catttcaaat ttttccatga ttctacacta
    15121 acacatcttt tctcttatgt aaagctttct ttacatagat gtcaattaag attctaaatc
    15181 acctgaactc ttgttaagtt tgatagaggt agtttcttct ttcccgttac gatagtaggt
    15241 tatcttaatg gtgtctccga tagaatggtt gtaaagagca ctttgtaagt ctgttgatga
    15301 agcaatctct ttgtcatcta cttttgtaat tacatcgtat ttttcaaggt gaccattggc
    15361 aggcatatta ctttgtaccg aacgaacaat tacaccagat gtaacattac ttggaatatt
    15421 gagtcttctg atgtcgcttg tactcacatt agataaatta accatctgga ttcccaaagc
    15481 tggacgcgtc acttttccgt ttttttctaa ctgttcaata atattgatag catcatttgc
    15541 aggaattgcg aaaccaagac cttctacaga tgttcctcca tttgtagcaa ttttacttga
    15601 ggtaattccg ataacctgcc cttgaatatt gatcagtggg ccgccagagt tacctgggtt
    15661 aatagcagta tcagtttgga tggcttttgt agaaatagct tgtccatctt ccgattttaa
    15721 ggatacattt ctattgagac tggatacgat accttgagtg acagtatttg catattcaga
    15781 acctaacggg ctaccgatgg caatagcagt ttctcctaca gttaacttac tagaatcacc
    15841 aaactcagct actgttgtca ctttttctga agagattttg acgacagcaa tatcagagaa
    15901 agtgtcagct ccgacaattt ctccaggtac tttagtccca tctgacaatc gaatatctac
    15961 tttgctggcg ccatttataa cgtgattgtt ggtgacgatg taagcttctt tatcattctt
    16021 tttataaata actccagatc cttcactaga gattcgctga gaatctgtgt cagtatcatc
    16081 attgccaaat acgctatttt gtctgtttgc cgaataagta ataacagaaa caacagcatc
    16141 ttttactttg ttaacagcct gtgttgttga attttcgttc ttataggcag tttgtgtaat
    16201 agtactattg ttgttagagt tgtttacact acttttttga gttagttgag ttattgaaaa
    16261 actacccaag gctccactaa aaaagctaat gacgataacg actaataatt gaaaccattt
    16321 tttgtaaaat gtttttagat gtttcatatt tgcctccata tgtttgaatt actgaaagta
    16381 taaactgact agcttaatta taacttaaac acaaaagttt tacacaaact gtggataact
    16441 cttttgaaac tgtgattttc ttaattgaaa tctatttttt attttgtgaa taagatgtga
    16501 aaaaatagag aatatgttag aatagagtca tgaaaattaa agttgtaaca gttgggaaac
    16561 tgaaagaaaa gtatttaaaa gatggtatcg cagagtattc aaaacgaatt tctagatttg
    16621 ctaagtttga aatgattgag ttatcagatg aaaaaacacc agataaggcc agtgaatcag
    16681 aaaatcaaaa gattttagaa atagaaggtc agagaatttt atcaaaaatt gctgaccgtg
    16741 atttcgttat tgtgttagcc attgaaggga aaactttctt ctcagaagaa ttgagtaagc
    16801 agttagaaga aacttctata aaaggatttt ctactcttac ttttattatt gggggaagtt
    16861 taggattgtc atcatctgta aaaaatagag ccaatctttc tgtcagtttt ggtcgcctaa
    16921 ccttgcctca tcagttaatg agactagttc ttgttgaaca aatctatcgc gcttttacga
    16981 ttcagcaggg attcccctac cataaataga aaattgactt ttaattgaat ttttggtaga
    17041 ataattgtgt taggtctcat agctcagctg gatagagcat tcgccttcta agcgaacggt
    17101 cgcaggttcg aatcctgctg ggatcaatat aatagcaaag ctgggaattt tcccggcttt
    17161 tttcttaaaa aagtacactt tgggagaaaa aaatgacagt tgagagaatt ttatctaaaa
    17221 cgaaattcca ttttgtataa tggtttttgt aagttagctt acaagaaaaa aacattttag
    17281 gagattttat tatgaaaaac acagttaaat tggaacagtt tgtagctttg aaggaaaaag
    17341 acttacaaaa gattaaaggt ggggagatga ggctgtcaaa attcttccgt gattttattt
    17401 tacaaagaaa aaagtaatga aataagggga aagagtaatg gatttatttg gatttgggac
    17461 agttattgtt cattttttaa ttattagtca caactaccat ttaatttgta aaggtcaaat
    17521 aaatagaaaa gaattattcg tttttggtgc ttatacatta ctaacagaaa tagtatttga
    17581 ttttccctta tatattctat atttagatgg gttagggatt gcaacatttt tatttccttt
    17641 gggcctatat tcctattttc gatggataaa acagtatgag agggatagag gactattcct
    17701 aagtttacta ctatctcttt tatatgagag cactcataac tttctgtccg taactttctc
    17761 ctctataaca ggagataatt ttgttttaca atatcatttc ccattctttt tcgttgtgac
    17821 ggtgttaacc tattttgtta cattaaaaat catttactat ttccatttgg aactagccta
    17881 ttttgacaag gactaccttt atcctttctt gaaaaaagta ttttttgctt tactattgct
    17941 acatattgta tctttcgttt cagatatggt aagtacgatt aaacatttga atagttttgg
    18001 aagtattttg tcatctattg tctttatctc tctccttttg accttctttg caatgaattc
    18061 tcataaagtt caaatggaga aagagattgc tttgaagcag aagaaatttg aacagaaaca
    18121 tttacagaat tacacagatg aaattgttgg tctgtataat gaaatccgtg gttttcgaca
    18181 tgattatgct ggaatgcttg tcagcatgca gatggcaatt gacagtggta atttacagga
    18241 aattgacaga atttacaatg aagttttagt caaagcaaat cataaattgc gttcagataa
    18301 gtacacttac tttgatttga acaacataga agactcagct ttacgaagtt tggttgctca
    18361 gtcaattgtc tatgctcgaa ataatggtgt agagtttaca ctggaagtaa aagatacgat
    18421 taccaagctt ccaattgaac tattggattt ggttcgtatc atgagcgttt tattgaataa
    18481 tgctgtcgaa ggatcggctg atagctataa aaagcagatg gaagtagcag ttattaagat
    18541 ggaaactgaa acagttattg tgattcagaa ttcatgtaaa atgacgatga ctccttcagg
    18601 agatctattt tccttaggat tctccactaa gggaagaaat cgcggagtcg gattaaataa
    18661 tgtgaaagaa ctactagata agtacaacaa tattatttta gaaacagaga tggaaggcag
    18721 tacatttaga caaatcatta gatttaagag ggaatttgaa tgaaagtttt aattttagaa
    18781 gatgttattg aacatcaagt gagactagag agaatattgg atgaaatttc gaaagaatcg
    18841 aatattccaa tatcatacaa gacaacggga aaagtccgtg aatttgaaga atacattgaa
    18901 aatgatgaag taaatcagct ttatttccta gatatcgata ttcatggaat tgagaaaaag
    18961 ggatttgaag tggctcagct cattcgtcat tacaatcctt acgctattat cgtctttatc
    19021 actagtcgat cagagtttgc gactctaacc tataaatacc aggtatcagc cctagatttt
    19081 gttgataagg atatcaatga tgagatgttt aagaagagaa ttgagcaaaa tatcttctac
    19141 acgaagagta tgttacttga aaatgaagat gttgtagatt atttcgacta caattacaag
    19201 ggaaatgatt taaaaattcc ttaccatgat attttgtata ttgaaacaac aggggtatct
    19261 cataaattgc gcattattgg taagaatttt gcaaaagagt tttatggtac catgacagat
    19321 attcaggaaa aggacaaaca tactcagcga ttttattctc ctcacaagtc atttttggta
    19381 aatataggca atatcagaga aattgatcga aaaaacttag aaattgtttt ctatgaagac
    19441 catcgttgtc ctatttcaag attaaaaatt agaaaattaa aagatatttt agagaaaaaa
    19501 tctcaaaagt gattgacaat tagcaagaaa ttgatataat ggttatatct gctacagata
    19561 gaaggtccgt tggtcaaggg gttaagacac cgccttttca cggcggtaac acgggttcga
    19621 atcccgtacg gactatttta tccgccatag ctcagttggt agtagcgcat gactgttaat
    19681 catgatgtcg taggttcgag tcctactggc ggagtataga taaaagggaa cacagctgtg
    19741 ttcctctttt tgtatcaatt tgtatcacca agcattttca taaggaagtc tgttatttct
    19801 tgagaacttt ctttttttcc atgtgcaatc caagtttggc agacaccaaa aagtgcatga
    19861 gttagataga tgctactata ttctaattca gtggtattta gattcagttg cataaatcgc
    19921 ttttgtaaat ctgtactaag catgatatga agtttatttc gtaagaaatt ttggatttct
    19981 ttagtcccat tttcagaaag aagggcagcc agaagtggtt ctgactctag atattcaaaa
    20041 acttctaaaa tagcgtctct tttgtgatga gcatgttttt gaaaaatata ttcaaatgta
    20101 tggaatagct tgctttgata gtgctcaatc atatcatact tatccttata gtgagtatag
    20161 aagctggaac gactaattcc ggctttttct actaatttga cagtagaaat tttatcaaat
    20221 ggctgttcca tcagtaattg taccatagca ttttcaatag ttcgctttgt ttttaagcgt
    20281 ttgttacttt cttgcatatt tcctccttgt aaataaatta gactatatgt ctaaaaatag
    20341 attttttatc ttgtaattta gattttttaa tgtataatct attatatcaa aattttagac
    20401 aatatgttta aaaaaggaga aactatgttt aaagaatgga aagcaattta aaaaaaacaa
    20461 cctttattat tgtcatgatc gggatttctc ttattccagc tctgtacaat atcatatttt
    20521 tgtcatcaat gtgggatcca tatgggcaat tgtctgactt atctgtggca gttgtaaata
    20581 atgataaaga ggcttcctat aatggtaata ctatggcaat aggaaaagac atggtgtcca
    20641 atttaaaaga aaataaaacc ttggattttc attttgtaga tgaagaggaa ggaaagaagg
    20701 gattggaaga tggcgattac tatatggtag tgactttacc aagtgattta tctaaaaaaa
    20761 caactacatt atccaatatt caatcgacag cagcttatca atcattgaca agtgagcaac
    20821 aaactgggat aagtgattct gtatctcaaa attcaactga tagtattcaa tcggctcagt
    20881 caattgtagc tttagtacaa ggtttacagg gaagtttaga aaacttacaa aatcaatctt
    20941 ctaatctttc gactttaaaa aatcaagcta atcaagtatt acctattact tctacttctt
    21001 tgataggatt gtcaagtgga ttaacagaga tacaaggagc tgttactagc aaattagttc
    21061 ctgccagtca gttgattgca tcaggtgtaa acgcatatac tacaggtgtt gataaagttt
    21121 ctcagggcgc aagtcaacta agtgaaaaaa atgccacctt gacaggtagt ttggataaac
    21181 tagtttcagg ctcaaacacc ttgacacaaa aatcttctag attgacagca ggagttggtt
    21241 aattacaatc aggatctggg caattagcag acaaatccag tcagttactt tcaggtgctt
    21301 ctccattaga gaatagagct aataaattgg cagatggatc tgggaaacta gcagaaggtg
    21361 gaacaaagtt aacttctgga ttggaagatt tacagacagg acttgcttct ttaggacaag
    21421 gactaggtaa tgctagtgat caactcaaat cagtatcaac agaatctaaa aatgcagaga
    21481 ttttgtcaaa tccactcaat ctttcaaaaa cagacaatga tcaagttcct gtaaatggaa
    21541 tcgcaatagc tccttatatg atatcagttg ctctttttgt tgcagcaata tcaacaaata
    21601 taatatttgc gaaattgcct tcaggacgtc atccagagag ccgttggcct tggttgaaat
    21661 ctcgagctga aataaatggt attatagctg ttttggcagg aattttggta tatggaggag
    21721 ttctattggt ttaactgcta atcatgagat gagaatattt attctcatca tccaaacaag
    21781 tttagtattc atgtctatgg tgaccacttt agcaacgtgg aatagccgta taggagcttt
    21841 tttctcactt attttgcttt tactatagtt agcatcaagt gcaggtactt atccacttgc
    21901 tttgacaaat gatttcttta gatctattaa tccctgttta ccaatgagct attcagtttc
    21961 gggattacga caaacaatct ctatcaacaa gtcattttcc tagctgtcat actagctcta
    22021 tttactggtt taggtatgct agcctatcaa cataagaaaa tggaagaaga ttaaaaaaat
    22081 cgaccgatta actggtcgat tttttatgcc ttagatgact ttcgtctgtg attatagatt
    22141 ccaaatagta agagagaagt aaaggaacag attgctccag taataaaacc attgggaatg
    22201 aaggaaagtg taatagttcc tttccccttg ggaatgtcaa ctttcataaa tccagtttga
    22261 gcttgtttaa tttctatttt cttaccatct tggtaggcag accaaccttt gtcataagga
    22321 atggtgaaga aaatagatgt atcttgttgg acatcatatg tagcaaaaac cttgttttta
    22381 taagttgata ctgtgacagg ttgttcttta attttttgaa ttgcctcggt gaaagttttg
    22441 gtatctaaac gatagaaggt aggagattca aatgatactt gtgaatttcc agggaaacta
    22501 acattgatat tgaaagtttt tttctcttta gtatatccta gattaaagaa ggagaagaca
    22561 ttatcagttg taaaagtctt tttttcacca tttacaagga tgtcaacctt cttttgttta
    22621 tcgttagaaa agtgaaggtt tatgaaagag agataaactt ggctgttttc tggaacttca
    22681 atttgatact ggattgctgc atcttcattt gaagaacttg tgatactaat caaatcatta
    22741 gtattttcta ttttttctgt tttttcataa ggtattggag aaaaataatc aaaattgacg
    22801 ttagcaagtt gatttaaaaa tgaggcctga ttatccaagg tatgttcatt gaacttgaca
    22861 tcattgtaaa cagattgact agcaactgca atcggaagag agtattgatt ttcatatagg
    22921 gtaagattat ctttttgata gatatcttta aagccatact tatcaatagg actgtctgag
    22981 atattgtact ggataccaaa taaactatca gccaaaatac tattatttgc atatcggaga
    23041 ttgagattag tcccagagga tttaaaacca agtttatcta aagtagagct tgatgaacga
    23101 tttcgaacag atgaaaattg agagattcca ttgtagttga atttcatact gtcatttcct
    23161 gtctgagttt gtagtttttc agtacgagta aattgatttc caatatatgt tgagaaagat
    23221 tccatagctg ggatatctcg actataagca cttcgagaag caaatcccca ttccttagca
    23281 attccgtcca tttgagatga agcatttaaa ctcatttcaa ccagtataaa taaagagatt
    23341 agaatggcaa atagattcac agatataaac tttttgataa ctgcaaggag taaaagagaa
    23401 tagacaacca aaaattcaag agtaagcaga atattcaaat ctgttaaaaa agaataatgc
    23461 gattttagat agatggtagc taaaaatcct gctactacaa gaaaaagcga aactaaaaaa
    23521 ttccagactt taagttcttt cagacgcttt aagacttctg ctgctgtgta aattaacaag
    23581 gtagagaaaa tccaagcata gcgatgtaaa aacatgtttg gagtatgcat gccttgccaa
    23641 aataagtcaa gagcttctat gtaaaagctt gcaattagaa atgcaaagaa tattacatat
    23701 atgagtttca cgtgaaactt aatagatttc agcgtaaaaa ataaaatggt caaaataaag
    23761 ggaaatagtc caacaaaaat cattgggatg gccccatact ttgttgtgtc aaaggaacca
    23821 atgaattgct tagcaaagag atcaagatac cagctacttt cagtttgaaa ctttgtaact
    23881 tcagtcaatt tttccccatg tgtctgtaaa tcaaatagag tgggaagagt cataatcaaa
    23941 ctagccatac cagctaaaaa ggagataact atgaaatcaa gaacagatga ttttcgagtc
    24001 ttaaagtccc acgaaatttg acagagatac cagaaaataa gaaacaatac tgtcatatat
    24061 ccaaaataat aattttgaat aaataagatt gacagacttg taaagtacaa taggagtttc
    24121 ttttcagtta tcagtagatg taaaccagtt ataattaaag gaatcaagat aaaaacatct
    24181 agccaggttt ttatctctaa ttgactgaca gtgaaactca tcagagcata ggaagtagat
    24241 aaggctagtt ttaaagcctg agggatagat tgaaacaatt tattcaaact aaaaaaggtt
    24301 gacagaccaa tcaatccaaa ttttaagaga gttgtcagat agatagcatc tggcatattc
    24361 gttagatcaa aaaagtaaac cagaggcgcg agaaaactac ccaagtaata actagatagg
    24421 gcatagaagt ttagccctag accacttgta aaggtgtaaa acagactact atttccatgt
    24481 aggatatttc gtaaggctac atcaaaaata acgtattgat gaaagccatc tcctaataga
    24541 ggagagttgt cgctattcca gtagatacct tgagatagat atactccaga cataatcact
    24601 acaggaatga tgaaagaaat aaaataggtt cgatatgttt ttaaaaatga tttcatgtta
    24661 cctcgtagaa tgatagaaaa ctcagttggt taacccaact gagttttgaa gttttattta
    24721 gtctttccaa agttctttaa cttttgcttg tacttctgca ttttctagga attcatcgta
    24781 ggtttcatcg atacggtcaa tgacgccatt tttagataag acaatgatat ggttagccaa
    24841 agtttgaata aattcgtggt catggctggc aaagatgatt gattctttaa agtttttcaa
    24901 tccatcattc aagcttgaga tagattccaa gtccaagtga tttgttggat catcaagtac
    24961 aaggacattt gattttaaga gcatgagttt tgaaagcatg acacgaactt tttctccccc
    25021 tgacaagaca tttacaggtt tgttaacttc atctccagag aagagcatac ggccgaggaa
    25081 gccacgtagg aaagtattgt catcttcttc tttacttgcg aattgacgca accagtcaag
    25141 aattgattct cctcctgcaa aatcagctga gttatctttt ggtaggtaag attgactagt
    25201 tgtaactccc cacttgacag ttccttcata gtcaatatct cccatgattg cacgaattaa
    25261 tgcagtcgtt tgaatatcat tttgtccaat aagtgctgtc ttatcatctg gacgcaagat
    25321 gaaactaata ttatccaaga tagtttcacc atcaatcttt acagttagat tttctactgt
    25381 caagagatca ttaccaatct cacgttccgc tttaaagttg ataaatggat atttacgact
    25441 agatggtaca atctcttcta gctcaatctt atcaagcatt ttcttacgtg atgttgcctg
    25501 ccttgactta gaagcattgg cagagaaacg agcaacgaat tcttgcaatt gtttaatttt
    25561 ttcttctgct ttagcattac ggtctgctag caatttagca gcaagctcag aagattcctt
    25621 ccagaagtcg tagtttccga catagagttt gatttttcca aagtcaaggt cggccatgtg
    25681 agtacaaact ttgtttaaga agtgacggtc gtgggatact acgataactg tgttatcaaa
    25741 gtcaatcaag aagtcttcta accaagtaat cgattggata tccaaaccgt tagtaggctc
    25801 gtccaagaga agaacatctg gtttaccaaa aagtgctttg gcgaggagaa cctttacttt
    25861 ttcaccgttg gccaattcgc tcatgttttg gtagtgtaat tcttctggaa tgtttaggtt
    25921 ttgaagtagt tgagaggctt cactctctgc ttcccaacct ccaagttcgg caaactctcc
    25981 ttcgagttcg gcagcacgaa ccccgtcctc gtctgagaaa tcttccttca tgtagatagc
    26041 atctttctct ttcatgatgc tataaagttt ttcatttccc atgataacga catcaatggc
    26101 acgttcatct tcgtagtcaa agtgattttg acgaagaaca gagagacgtt catctggacc
    26161 aagagagatg tgaccagtag taggttcgat atctccagct aaaattttta aaaaggttga
    26221 ttttccggca ccattagcac cgattaatcc gtaagtattt ccttctgtaa atttgatatt
    26281 gacatcatca aaaagtttgc gatcactaaa acgtagtgaa acatcagata ctgtaagcaa
    26341 tatttttctc ctatatgtgt aatatattta ttctactaga aaatacagaa atattcaaat
    26401 ttttatttgt caattttgtg taaattatat ttacagtatc ctttacacaa atctgtaaaa
    26461 agcaaggctg atttattttg ataaattacg gttatttcat taaaaaaatg ctataattga
    26521 aaggactata tcgaaggaga acaaaatgac taaacccatt attttaacag gagaccgtcc
    26581 aacaggaaaa ttgcatattg gacattatgt tggaagtctc aaaaatcgag tattattaca
    26641 ggaagaggat aagtatgata tgtttgtgtt cttggctgac caacaagcct tgacagatca
    26701 tgccaaagat cctcaaacca ttgtagagtc tatcggaaat gtggctttgg attatcttgc
    26761 agttggattg gatccaaata agtcaactat ttttattcaa agccagattc cagagttggc
    26821 tgagttgtct atgtattata tgaatctagt ttcgttagca cgtttggagc gaaatccaac
    26881 agtcaagaca gagatttctc agaaaggatt tggagaaagc attccgacag gattcttggt
    26941 ctatccaatc gctcaagcag ctgatatcac agctttcaag gctaattatg ttcctgttgg
    27001 gacagatcag aaaccaatga ttgagcaaac tcgtgaaatt gttcgttctt ttaacaatgc
    27061 atataactgt gatgtcttgg tagagccgga aggtatttat ccagaaaatg agagagcagg
    27121 gcgtttgcct ggtttagatg gaaatgctaa aatgtctaaa tcactaaata atggtattta
    27181 tttagctgat gatgcggata ctttgcgtaa aaaagtaatg agtatgtata cagatccaga
    27241 tcatatccgc gttgaggatc caggtaagat tgagggaaat atggttttcc attatctaga
    27301 tgtttttggt cgtccagaag atgctcaaga aattgctgat atgaaagaac gttatcaacg
    27361 aggtggtctt ggtgatgtga agaccaagcg ttatctactt gaaatattag aacgtgaact
    27421 gggtcctatt cgtgagcgcc gtattgaatt tgctaaggat atgggagaag tttataatat
    27481 gattcaaaaa ggtagtgaaa gagcgcgtga agttgcgggt caaaccctat ctgaggtaaa
    27541 aggggcaatg ggacttcatt actttaatta agtttatttt acaagaaact atcatttcta
    27601 tctcgaagaa aagatagttt tttatttacc cctgtaacat ttgacaaatt tttatagaat
    27661 ggtatgatag atacaatata aaaagagtca agctcaaaaa gaaagaaaag aggaaacttc
    27721 gaatgtctaa ttgggacact aaatttttga aaaaaggttt tacctttgat gatgtattgc
    27781 ttattccagc tgaaagtcat gtgttgccta acgatgcaga tttaacaact aaattggcag
    27841 ataatttgac tttaaatatc ccaattatta ccgctgccat ggacacagtt acagagagtc
    27901 aaatggccat tgctattgct cgtgcaggtg gtctcggagt tatccataaa aacatgtcaa
    27961 ttgctcaaca agcagacgag gttcgtaagg taaaacgttc tgaaaatgga gttattattg
    28021 atccgttctt cttgacgcct gaacatacaa ttgctgaagc agatgagctt atgggtcgtt
    28081 accgcatcag tggtgttcca gttgttgaaa cacttgaaaa tcgtaaattg gttggtattt
    28141 tgacaaaccg agatcttcgt tttatttcag attataatca accaatttca aaccatatga
    28201 ctagtgaaaa tcttgttact gctcctgtgg gtacggatct tgcaacggct gagagtattc
    28261 ttcaagagca tcgtattgaa aaacttccgt tggtcgatga agaaggcagt ctttctggtt
    28321 tgatcactat caaagatatt gaaaaagtta ttgagtttcc aaatgcggct aaagatgaat
    28381 ttggtcgtct tctagttgca ggtgcagtag gtgttacttc agatacattt gaacgtgcag
    28441 aggctctttt tgaggcagga gcggatgcga ttgttattga tactgcacat ggtcattctg
    28501 caggtgtctt gcgtaaaatt gccgagattc gtgctcattt cccagatcgg actttgattg
    28561 ctggaaatat tgctactgct gaaggtgcac gtgcccttta tgaagcgggt gtagacgttg
    28621 ttaaggttgg tattggacca ggttctatct gtactactcg tgtgattgct ggtgttggtg
    28681 ttccgcaagt aacagctatc tacgatgctg cagctgttgc gcgcgaatat ggtaaaacga
    28741 ttattgctga cggtgggatc aagtattctg gagatattgt aaaagcactt gctgcaggtg
    28801 gaaatgctgt tatgcttgga tctatgtttg ctggaactga tgaagctcca ggcgaaactg
    28861 aaatcttcca aggacgtaaa ttcaagactt accgtggtat gggatcaatt gctgctatga
    28921 agaaaggttc aagcgaccgt tatttccaag gttctatcaa tgaagcaaac aagctcgttc
    28981 cagaaggaat tgaaggtcgt gttgcttata aaggagcggc agctgatatt gttttccaaa
    29041 tgattggtgg tattcgctct ggtatgggtt actgtggtgc agctaacctt aaagaactac
    29101 acgataatgc tcaatttatt gaaatgtctg gtgctggttt gaaagaaagc catcctcatg
    29161 atgtgcaaat tactaatgag gcaccaaatt attctatgta aaaaacaatg aaaagaactc
    29221 cagtgaaaac aggagttctt ttacaatgtt gtcaatttcc atttacagca gctttaccat
    29281 cctgaatagt gaagatactt agattttctg gtagattttg aagatggtct aagcttgttg
    29341 ttgtgataaa ggtttggatt gattgagaaa tcgtttctaa taattttaat tgtctagtgt
    29401 tgtcaagttc actcatcaca tcgtcaagca gtaatatagg agattctgtg gtaatgcttt
    29461 ccattaattc gatttctgct aattttatcg agaggacgag actacgatgt tgaccttggc
    29521 ttccgaaact agcatccatc ccatttatat aaaaagaaat gtcatctcga tgaggaccga
    29581 caccagtatt ctttttaaat aaatctctgg atttactttt ttctaaagca attttgaaag
    29641 attcggataa gttttgtttg tcagttatat tgacagaaga ttgataggat attgacaact
    29701 cttcgatctg attagagagt tcaaaatgtt tcttacgccc aaatgattct agttttttta
    29761 tgaaatctaa gcggtgattc attacacgac atccataatc aactagctga tcatctaaca
    29821 cagaaaggaa tgtttcatct attttttgat ctgattttag gtaagtgttt ctttgcttta
    29881 ggatgtggtt ataattggtt aagtcagata agtagattgg cttaatttgc ccaagttcca
    29941 tatcgatgaa ttttcgtcga atcgaaggtg ctcctttaat tagttgtaaa tcttcaggag
    30001 caaataagac aacattcatg tgtcctacat aatctgaaag gcgtgcctgt tttaagtgat
    30061 taacttttgt tacacggcct ttttgtgtta gttcgatttc taggggaatg gatccagttt
    30121 ttttctgaac gagacctgaa agatgaagtt gttcctcatc aaaatgaatg agatttttat
    30181 ctgttcgagt tcgatgacta cgcgttaagg ctaaaaaata gatagcctct aacatgtttg
    30241 tttttccttg tgcattacgt cccaaaaaga cattcaattt aggattaaag tctattttcg
    30301 tttctttgta attacgaaaa gtcttgagag atagatgttg tagccacatg attatctacc
    30361 agggaatcgt ggagcttgtt ggcttttagg tgatgaagca ggtttcgatt tgtctttttt
    30421 aactccctta ttcatctttt tgacaagttt agcgatccgt tctttttcaa ctttatcagc
    30481 ttggtattca tcttgttctt cagaagtagg ttgtgtcaac aagatgtcaa tgttcatgtc
    30541 agggatgtca actttatcgc caatacgaag tttttttcca cgacgactct ctaattccct
    30601 attaaagtaa acagaatgtt cagagagaaa tgatttaata gctcctccgc tatgtgtaat
    30661 tccaagttct ttgagtagtg cttggagggt aataaattct tcaaataatt tgtattccat
    30721 aattcacctc aatctttggt attataccat attttcctaa aaatagtgag agagacagcg
    30781 agaaatgtaa gcgattttta tttcaaaagt gttacaggga acaagaaaat ttcaggtttt
    30841 cgtgatataa tagaagtctg tatataagga ggtaaatcat ggagttagtg catggaattt
    30901 caacacattt tatccaatca aaaaagttta aaacaaacaa aattaccgtg cgttttaccg
    30961 ctccattatc ccttgatacg attgcaggtc acatgttgag tgcaagtatg ctagagactg
    31021 ctaatcagat gtaccccact tctcaagatt tgaggagaca cttggccagt ctatacggta
    31081 cagatatgtc aaccaattgt ttcagaagag ggcaaagcca cattatagaa ttgacattta
    31141 cctatgttcg tgatgagttt ttaagtagga aaaacgtgct aacctctcag attttggaac
    31201 ttgtaaaaga aactcttttt tcacccgtag tagttgataa tgggtttgat ccggccttat
    31261 ttgaaattga gaaaaaacaa ttgctagcaa gtttagcagc tgatatggat gattcttttt
    31321 attttgcaca taaagaattg gataaattgt tttttcatga tgaacgtctt caattggaat
    31381 atagtgattt acgaaatcgt attttagctg aaactccaca aagttcttac tcttgtttcc
    31441 aagaattttt agccaatgat cgaatagatt tctttttcct aggtgatttt aatgaggttg
    31501 aaattcaaaa tgtattagaa tcatttggct ttaaaggtcg aaaaggagat gtgaaggttc
    31561 agtattgtca accttattct aatatccttc aggaaggtat ggttcggaaa aatgtgggac
    31621 aatccatttt ggaattaggt tatcattacc gttctaaata tggtgatgaa caacatttac
    31681 ccatgattgt aatgaatggt ttacttggtg gatttgctca ctctaagctc tttacaaatg
    31741 tccgtgaaaa tgctggatta gcttatacca tttcaagtga gcttgattta tttagtggat
    31801 tcttgaggat gtatgctggt atcaatcgag aaaatcgtaa ccaggctcgt aaaatgatga
    31861 ataatcaact gcttgattta aaaaaaggtt attttacaga gtttgagtta aatcagacca
    31921 aggaaatgat tcgttggtcg ttgttacttt ctcaagataa tcaatcttca ttgattgaac
    31981 gtgcttatca aaatgcctta tttggaaaat cttcagcaga ctttaaaagt tggattgcaa
    32041 agcttgaaca aattgacaaa gatgctattt gtagagtagc taataatgtg aaactacaag
    32101 cgatttactt tatggaagga atagaatgac aaaggttgtt tttgaagaaa aatactatcc
    32161 agctgtaaaa gaaatggttt atcgaactcg tttggccaac ggattgacag ttgctctttt
    32221 gcctaaaaag gaatttaaag aggtttacgg gagtgtcact gtacagtttg gttcggtaga
    32281 tacgtttgtc acagaagttg acggagatgt aaaacaatat cctggaggaa ttgctcattt
    32341 tcttgaacat aaattatttg agagagaaga ttctagtgat ttgatgtcgg cttttacgag
    32401 tctaggtgca gatagtaatg cctttacaag ctttacaaaa acaaactatc ttttttcagc
    32461 aacggattat tttttagaaa atttagattt acttgatgaa ttggtaacat cagcacactt
    32521 tactgaagct tccattttga cagagcagga tattattcag caagaacgag aaatgtacca
    32581 agatgatcca gattcgtgtt tattcttttc aactttagcg aatttgtatc ctggtacacc
    32641 tttagcaact gatatagttg gaagtgagga gtccatttcc caaatcaatc taactaattt
    32701 gcaagaaaat tttacaaagt tttacaaacc tgtaaacatg tctctgtttt tagttggtaa
    32761 ttttgatgtg gagcgagtac aggactattt tgaaagcaaa gaactgaaag attcagattt
    32821 tcaggaagta gcaagagaaa agttgttttt acagcctgta aagccaacag atagtatgag
    32881 aatggaagta tcttctccca aactagcgat tggagttaga ggtaagcgag aagtttctga
    32941 agcggattgc tatcgacatc atattttatt aaaattattg tttgcaatga tgtttggttg
    33001 gacttcggat cgttttcaaa aatgttatga atcaggtaaa attgatgcat ccttatctct
    33061 ggaagttgaa gtaacaagtc gctttcattt tgtcatgttg acaatggata cgaaagagcc
    33121 agttgctttg tctcatcaat ttaggaaggc tattcgtaat tttacaaagg atttagatat
    33181 tacagaggaa catttagata ttatcaaaag agagatgttt ggcgaatttt tcagtagcat
    33241 gaactctctt gaatttattg caacgcaata tgatgctttt gaaaatggtg agacaatttt
    33301 tgatttgccg aaaattttac aggaaattac tttagaggat gtccttgatg ctggacatca
    33361 tttaatagat gatggtgaca tagttgattt tacaatattc ccatcgtagt aacctattat
    33421 aatagacact agaaagaagg gatgacaagt atgagaaaaa aaacaattgg agaggtttta
    33481 cgattagcta gaatcaatca gggattgagt ttagatgaat tgcagaaaaa gacagaaatc
    33541 cagttagata tgttggaagc aatggaagca gacgatttcg atcaacttcc aagtcctttt
    33601 tacacgcgtt ctttcttgaa aaaatatgca tgggctgttg agttagatga ccaaattgtt
    33661 ttggatgctt atgattctgg gagtatgatt acttatgagg aagtagatgt tgatgaagat
    33721 gagttgacag gtcgtagacg ttcaagtaag aaaaagaaga aaaaaacatc atttttacct
    33781 ttattttatt ttatcctttt tgctttatcg attttaattt ttgtgactta ttatgtttgg
    33841 aactatattc aaactcaacc agaggagcct tctctttcta attacagtgt ggttcaatca
    33901 acaagttcaa ctagctctgt tccccactcc tcaagtagta gttcttctag tatagaatca
    33961 gctataagtg tatcaggcga aggaaatcat gtagaaatcg cttataagac aagtaaggaa
    34021 acagttaaat tgcaattggc agtttcagat gttacaagtt gggtcagtgt ttcagaaagc
    34081 gaacttgagg gcggtgtaac cttatcgcca aagaagaaaa gtgcagaagc aacagttgca
    34141 actaaaagtc ctgtaacaat tacgttaggt gttgtaaaag gtgttgattt gacagtagat
    34201 aatcagactg ttgatttatc gaaattaaca gctcagactg gacaaatcac tgtaaccttt
    34261 actaaaaatt aaggaaaaac gaatgaaaaa agaacaaatt cccaatctct taacaatagg
    34321 tcgaattctc tttataccta tttttatctt tattttaacg ataggaaatt cgatagagag
    34381 tcatatagtt gcagctatta tctttgctgt tgccagtatt accgactatt tagatggata
    34441 tttagctcgt aaatggaatg tggtcagtaa ttttggtaaa tttgcagatc ctatggcgga
    34501 taagttacta gttatgtcgg cttttattat gttgattgag ttaggtatgg ctccggcttg
    34561 gattgttgca gtgattatct gtcgtgagtt agctgtgaca ggtttaaggc ttttattggt
    34621 tgaaactggt ggaacaattt tagcagcagc aatgcctgga aaaattaaaa cttttagtca
    34681 gatgtttgct attattttct tgctattaca ttggactttg cttggtcaag ttctacttta
    34741 tgtagcctta tttttcacta tctactctgg ctatgactat ttcaagggta gtgcctatgt
    34801 atttaaaggg acatttggtt cgaaatgaaa tcaataattg atgtaaaaaa tctttctttt
    34861 cgctataaag aaaatcagaa ctactacgat gtgaaggata ttacgtttca cgtgaaacgt
    34921 ggagaatggc tttcgattgt agggcataat ggtagtggta aatcaactac ggttcgatta
    34981 attgatggct tactggaagc agaatccgga gagattgtaa ttgatggcca acgtttgact
    35041 gaggaaaatg tttggaatat acgtcgtcaa atcggtatgg tttttcaaaa tccagacaat
    35101 caatttgttg gagcgactgt tgaagatgat gttgcttttg gtttggaaaa tcagggactt
    35161 tctcgtcaag aaatgaaaaa gagagtggaa gaagctctgg ctttagttgg catgttggac
    35221 tttaaaaaga gagagccagc gcgtctatca ggtggtcaaa agcaacgtgt ggccattgca
    35281 ggtgttgtag ccctaagacc agctatttta atcttagatg aagcaacgag tatgttggat
    35341 cctgaggggc gtagagaact tattgggaca gtaaaaggaa ttcgaaaaga ctatgatatg
    35401 acggtcattt ctattaccca tgatttggaa gaagtcgcca tgagtgatcg cgtattggtc
    35461 atgaaaaaag gggaaattga atcaactagt agtccaaggg agcttttctc tcgaaatgat
    35521 ttagatcaaa ttggattaga cgatcctttt gctaatcaat taaaaaaatc tttgagccag
    35581 aatggctatg atttacctga aaattatttg acagaaagtg agctagagga taagctatgg
    35641 gaattgctct agaaaatgtg aattttacat atcaagaagg tactccctta gcttcagcag
    35701 ctttgtcgga tgtttctttg acgattgaag atggctctta tacagcttta attgggcaca
    35761 caggtagtgg taaatcaact attttacaac tcttaaatgg tttattggtg ccaagtcaag
    35821 ggagtgtgag ggtttttgat accttaatca cctcgacttc taaaaataaa gatattcgtc
    35881 aaattagaaa acaggttggc ttggtatttc agtttgctga aaatcagatt tttgaagaaa
    35941 cggttttgaa ggacgttgct tttggaccgc aaaattttgg agtttctgaa gaagatgctg
    36001 tgaagactgc gcgtgagaaa ctggctctgg ttggaattga tgaatcactt tttgatcgta
    36061 gtccgtttga gctgtcaggg ggacaaatga gacgtgttgc cattgcaggc atacttgcca
    36121 tggagccagc tatattagtc ttagatgagc caacagctgg tctagatcct ctagggagaa
    36181 aagagttgat gaccctgttc aaaaaactcc accagtcagg gatgaccatc gtcttggtaa
    36241 cgcatttgat ggatgatgtt gctgaatatg caaatcaagt ctatgtaatg gaaaagggac
    36301 gtttagtaaa ggggggcaaa ccaagtgatg tctttcaaga cgttgttttt atggaagaag
    36361 ttcagttggg agtacctaaa attacggcct tttgtaaacg attggctgat agaggcgtgt
    36421 catttaaacg attaccgatt aagatagagg agttcaagga gtcgctaaat ggatagtatg
    36481 attttggggc gttatatccc aggggattcg attgttcacc gattggatcc acgtagcaaa
    36541 ttgcttgcta tgatgctact gattttgatt gtgttttggg ctaataaccc cttgacgaat
    36601 ctgattcttt ttatagcgac agggatattt attgccttgt caggagtatc tctttcattt
    36661 tttattcagg gcttgaagtc tatgtttttc ttgattgcct tcacaactat ttttcaacta
    36721 tttttcattt ctaatgggaa tgttttattt gagttttcgt ttgtgagaat cacggattat
    36781 gctttgcaac aagctgggat tattttttgt cgctttgtat tgattatttt cttttcaact
    36841 ttgttaacct taacaaccat gcctttaagt ttggcatcag ctgtcgaagc tttattagca
    36901 cctttaaagc gtgtgaaagt tccagttcat gaaattggat tgatgctgtc tatgagtttg
    36961 cgttttgtcc caaccttgat ggatgatacg actcggatta tgaatgcaca gaaagctcgt
    37021 ggagtggatt ttggagaagg aagcatcgtt caaaaagtaa aggcgatgat tcccattttg
    37081 attcctcttt ttgcgacaag tttaaaacgt gcagattcct tggctatcgc tatggaagcg
    37141 cgtggctatc agggtggaaa aggcagaagt caataccgac aattgaaatg gactctaaag
    37201 gatacgctga ccattcttgt tattctcgta cttggttgtt gtttattttt cttaaaatct
    37261 tagtagcttt caggaattga taaaaagtta ctgtaacagt ttttgatata aaggtaggga
    37321 tatgaaccgt tttaaaaaat caaaatatgt cattattgtt tttgtcactg ttctgcttgt
    37381 gtcagctctc ttagcgacga cttattcaag tacaattgtg acaaaattag gagatggaat
    37441 ctcattggtt gatagagttg tacaaaaacc ttttcagtgg tttgattctg tcaaatcaga
    37501 tttggctcat ttgacacgaa catataatga aaatgaaagt ttgaagaaac agctttacca
    37561 attagaagtt aaatcaaatg aggtggaaag tttaaagaca gaaaatgaac aactgcgcca
    37621 attgcttgat atgaagtcta aattgcaagc cacaaagact ttagcagcag atgttattat
    37681 gcgttctccg gtatcttgga agcaggagtt gaccttagat gcaggtagat caaaaggtgc
    37741 ttctgagaac atgttagcta ttgcaaatgg tggcttgatt gggagtgttt caaaagtaga
    37801 ggagaactct actatagtca accttctgac aaatacggaa aatgctgata agatttctgt
    37861 taaaattcaa catggctcta ctacaattta tggaattatt attggctatg acaaggaaaa
    37921 tgacgttctt aaaattagcc aattaaatag taatagcgat attagtgcgg gagataaggt
    37981 gactactggt ggattaggaa actttaacgt tgctgatatt cctgttggtg aagtggttgc
    38041 cacaacgcat agtacagact atttgacacg agaagtaact gttaaattga gtgcagatac
    38101 tcataatgta gatgtgatag aattagtggg gaattcataa tgagacagtt gaagcgagtt
    38161 ggagtatttt tattgcttcc tttctttgtt ctaattgacg cccatattag ccagcttctg
    38221 ggctcatttt tcccccatgt acatttggct agtcattttc tttttctatt tctcttattt
    38281 gagacgatag aagtatcaga gtatctctac ctagtctatt gttttgttat aggcttggtt
    38341 tatgatgttt actttttcca tctaataggg attacaactc tcttatttat cttattggga
    38401 gccttccttc ataaattgaa tagtgttatt ttgttgaatc gttggacaag aatgctagct
    38461 atgattgtgc tgacattcct gtttgaaatg ggtagttatc ttttggcttt tatggtaggg
    38521 ttgacagtag atagcatgtc gatttttata gtctatagct tggtaccgac gatgatttta
    38581 aattttttat ggattactgt ttttcaattt atttttgaaa aatattatct ataagaacga
    38641 catataaatg taacaaaggc gtaatattta ttaggccttt ttttggtata ctagtattgt
    38701 ctttaaaaga aggagtatct acgtaatatg aagaaaaaaa tcttagcgtc acttttatta
    38761 agtacagtaa tggtttctca agtagctgtt ttaacaactg cgcatgcaga aacgactgat
    38821 gacaaaattg ctgctcaaga taataaaatt agtaacttaa cagcacaaca acaagaagcc
    38881 caaaaacaag ttgaccaaat tcaggagcaa gtatcagcta ttcaagctga gcagtctaac
    38941 ttgcaagctg aaaatgatag attacaagca gaatctaaga aactcgaggg tgagattaca
    39001 gaactttcta aaaacattgt ttctcgtaac caatcgttgg aaaaacaagc tcgtagtgct
    39061 caaacaaatg gagccgtaac tagctatatc aataccattg taaactcaaa atcaattaca
    39121 gaagctattt cacgtgttgc tgcaatgagt gaaatcgtat ctgcaaacaa caaaatgtta
    39181 gaacaacaaa aggcagataa aaaagctatt tctgaaaaac aagtagcaaa taatgatgct
    39241 atcaatactg taattgctaa tcaacaaaaa ttggctgatg atgctcaagc attgactacg
    39301 aaacaggcag aactaaaagc tgctgaatta agtcttgctg ctgagaaagc gacagctgaa
    39361 ggggaaaaag caagtctatt agagcaaaaa gcagcagctg aggcagaggc tcgtgcagct
    39421 gcggtagcag aagcagctta taaagaaaaa cgagctagcc aacaacaatc agtacttgct
    39481 tcagcaaaca ctaacttaac agctcaagtg caagcagtat ctgaatctgc agcagcacct
    39541 gtccgtgcaa aagttcgtcc aacatacagt acaaacgctt caagttatcc aattggagaa
    39601 tgtacatggg gagtaaaaac attggcacct tgggctggag actactgggg taatggagca
    39661 cagtgggcta caagtgcagc agcagcaggt ttccgtacag gttcaacacc tcaagttgga
    39721 gcaattgcat gttggaatga tggtggatat ggtcacgtag cggttgttac agctgttgaa
    39781 tcaacaacac gtatccaagt atcagaatca aattatgcag gtaatcgtac aattggaaat
    39841 caccgtggat ggttcaatcc aacaacaact tctgaaggtt ttgttacata tatttatgca
    39901 gattaattta cagagggact cgaatagagc cctcttttca ggttttaccg tgacaatccc
    39961 tattaaaaat tatatcaaaa tagcttgaaa atattggaaa agtatggtag aatgaaaatt
    40021 gtcgtgtgaa cgataatact cattcttgat gaattgtgaa gcagttgccc ttgggtcgtt
    40081 ttgcgagttg aagtcaagaa gaggaaaaaa acaaaaagga gaaatactca tggcagtaat
    40141 ttcaatgaaa caacttcttg aggctggtgt acactttggt caccaaactc gtcgctggaa
    40201 tcctaagatg gctaagtaca tctttactga acgtaacgga atccacgtta tcgacttgca
    40261 acaaactgta aaatacgctg accaagcata cgacttcatg cgtgatgcag cagctaacga
    40321 tgcagttgta ttgttcgttg gtactaagaa acaagcagct gatgcagttg ctgaagaagc
    40381 agtacgttca ggtcaatact tcatcaacca ccgttggttg ggtggaactc ttacaaactg
    40441 gggaacaatc caaaaacgta tcgctcgttt gaaagaaatt aaacgtatgg aagaagatgg
    40501 aactttcgaa gttcttccta agaaagaagt tgcacttctt aacaaacaac gtgcgcgtct
    40561 tgaaaaattc ttgggtggta tcgaagatat gcctcgtatc ccagatgtga tgtacgtagt
    40621 tgacccacat aaagagcaaa tcgctgttaa agaagctaaa aaattgggaa tcccagttgt
    40681 agcgatggtt gacaccaata ctgatccaga tgatatcgat gtaatcatcc cagctaacga
    40741 tgacgctatc cgtgctgtta aattgatcac agctaaattg gctgacgcta ttatcgaagg
    40801 acatcaaggt gaggatgcag tagcagttga agcagaattt gcagcttcag aaactcaagc
    40861 agattcaatt gaagaaatcg ttgaagttgt agaaggtgac aacgcttaat ttatacaaat
    40921 agtaattacc taggagggcg gggcttagcc cggctctcct attttcaaaa aatataggag
    40981 aattaaaatg gcagaaatta cagctaaact tgtaaaagag ttgcgtgaaa aatctggtgc
    41041 cggtgttatg gacgctaaaa aagcgcttgt agaaacagac ggtgacatcg aaaaagcgat
    41101 tgaattgctt cgtgaaaaag gtatggctaa ggcagctaag aaagctgacc gtgttgctgc
    41161 agaaggtttg actggtgttt atgttaacgg taatgttgca gcagttattg aagtaaacgc
    41221 tgaaactgac ttcgttgcaa aaaacgctca attcgttgaa ttggtaaata ctacagctaa
    41281 agtcattgct gaaggaaaac ctgctaacaa tgaagaagct cttgctttga taatgccttc
    41341 aggtgaaact cttgaagctg catacgtatc tgcaacagca actatcggag agaaaatctc
    41401 attccgtcgc tttgcattga ttgaaaaaac agacgcacaa cactttggag cataccaaca
    41461 taacggtgga cgtatcggtg ttatttcagt tgttgaagat ggagacgaag cacttgctaa
    41521 acaattgtca atgcacatcg cagcgatgaa accaacagtt ctttcttaca aagaattgga
    41581 tgagcaattc gttaaagatg agttggcaca attgaatcac gttatcgacc aagacaacga
    41641 aagccgtgca atggttaata aaccagctct tccacacttg aagtatggat caaaagctca
    41701 attaactgat gatgttattg ctcaagctga agctgacatc aaagctgaat tggctgcaga
    41761 aggcaaacca gaaaaaatct gggacaaaat tattccaggt aaaatggatc gcttcatgct
    41821 tgataacact aaagttgacc aagcttacac acttcttgca caagtttaca tcatggatga
    41881 cagcaagaca gttgaagcat accttgaatc agttaacgct tcggtagttg agtttgctcg
    41941 ctttgaagtt ggtgaaggta tcgagaaagc tgcaaacgac ttcgaagctg aagttgcagc
    42001 tacaatggca gcagccttga ataactaata atagaaagga agcaaattgc ttcctttttt
    42061 gtatagggct tagatttttc ctgaaattgt tttttcccca gtctcactcg attagaataa
    42121 ttaaaacaaa aagccctata ataagggcta agtgcattta ggagactata cttcaaattc
    42181 atagtaagcg cgtcataaca aggtatctat cctaattccc caacttccag tatactagat
    42241 aaaaaataat tatcggagga aaggtattgt actatgataa ttcaactaag tgatttaggt
    42301 caagttcacc ttgtttgtgg caagacagat atgaggtagg gaatagactc attagcctat
    42361 gtagttaaaa cccactttga attggattct ttctccggtc aagtctttct cttttgtggt
    42421 ggacgtaaag accgctttaa agccctttac tgggatggtc aaggattttg gctactatat
    42481 aaacgctttg agaacggaaa actgacttgg ctaagtacag aaaaggatgt caaagctctc
    42541 gcacctgaac aagtagattg gcttatgaag ggcttttcta tcactccaaa aatatagtag
    42601 attgaaacta gaatagtaca cctctgcttc taaaacattg ttagaaatcg atttgattgt
    42661 cctgttctta tttcatttta ctataaatcc atcagaaagt tgtgatttct attgaaatga
    42721 ggactttctt tttacactca tctgctttca aaaagcattc tagtccat
//
LOCUS       DBEJKC010000012        41725 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.012, whole genome shotgun sequence.
ACCESSION   DBEJKC010000012 DBEJKC010000000
VERSION     DBEJKC010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 41725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41725
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.012"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(175..1161)
                     /locus_tag="ACL3G6_000644"
     CDS             complement(175..1161)
                     /locus_tag="ACL3G6_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0545220.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(1171..1971)
                     /locus_tag="ACL3G6_000645"
     CDS             complement(1171..1971)
                     /locus_tag="ACL3G6_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HGR0545221.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(2224..3066)
                     /locus_tag="ACL3G6_000646"
     CDS             complement(2224..3066)
                     /locus_tag="ACL3G6_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HGR0545222.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(3068..4360)
                     /locus_tag="ACL3G6_000647"
     CDS             complement(3068..4360)
                     /locus_tag="ACL3G6_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGR0545223.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(4471..5742)
                     /locus_tag="ACL3G6_000648"
     CDS             complement(4471..5742)
                     /locus_tag="ACL3G6_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR0545224.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            6276..7808
                     /gene="malQ"
                     /locus_tag="ACL3G6_000649"
                     /pseudo
     CDS             6276..7808
                     /gene="malQ"
                     /locus_tag="ACL3G6_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
     gene            7834..10092
                     /gene="glgP"
                     /locus_tag="ACL3G6_000650"
     CDS             7834..10092
                     /gene="glgP"
                     /locus_tag="ACL3G6_000650"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HGR0545225.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYKVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(11137..11709)
                     /locus_tag="ACL3G6_000651"
     CDS             complement(11137..11709)
                     /locus_tag="ACL3G6_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545226.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     SAMNLLSPGTYLTQLWDKNDAIPNNGRINF"
     gene            11787..11993
                     /locus_tag="ACL3G6_000652"
     CDS             11787..11993
                     /locus_tag="ACL3G6_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545227.1"
                     /translation="MLKKYFSKYKWTDLFWILFVIGACLLTGNSSLFPLTHQEFSFRG
                     SVWGLVLALYHLLFIDKFVISNRK"
     gene            complement(12334..13182)
                     /locus_tag="ACL3G6_000653"
     CDS             complement(12334..13182)
                     /locus_tag="ACL3G6_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative RNA methyltransferase"
                     /protein_id="HGR0545228.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            13334..13612
                     /locus_tag="ACL3G6_000654"
     CDS             13334..13612
                     /locus_tag="ACL3G6_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6110 family protein"
                     /protein_id="HGR0545229.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            13614..15677
                     /locus_tag="ACL3G6_000655"
     CDS             13614..15677
                     /locus_tag="ACL3G6_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGR0545230.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(15755..17011)
                     /gene="tyrS"
                     /locus_tag="ACL3G6_000656"
     CDS             complement(15755..17011)
                     /gene="tyrS"
                     /locus_tag="ACL3G6_000656"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HGR0545231.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            17153..19618
                     /gene="pbp1b"
                     /locus_tag="ACL3G6_000657"
     CDS             17153..19618
                     /gene="pbp1b"
                     /locus_tag="ACL3G6_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1B"
                     /protein_id="HGR0545232.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLCFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLATADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            19683..20594
                     /locus_tag="ACL3G6_000658"
     CDS             19683..20594
                     /locus_tag="ACL3G6_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR0545233.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            20824..21522
                     /gene="dapD"
                     /locus_tag="ACL3G6_000659"
     CDS             20824..21522
                     /gene="dapD"
                     /locus_tag="ACL3G6_000659"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HGR0545234.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            21590..22720
                     /locus_tag="ACL3G6_000660"
     CDS             21590..22720
                     /locus_tag="ACL3G6_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HGR0545235.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDDAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            22732..23271
                     /locus_tag="ACL3G6_000661"
     CDS             22732..23271
                     /locus_tag="ACL3G6_000661"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HGR0545236.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMEFVAYDPQQLVKTSFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            23255..23932
                     /locus_tag="ACL3G6_000662"
     CDS             23255..23932
                     /locus_tag="ACL3G6_000662"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HGR0545237.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(23999..24898)
                     /gene="galU"
                     /locus_tag="ACL3G6_000663"
     CDS             complement(23999..24898)
                     /gene="galU"
                     /locus_tag="ACL3G6_000663"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGR0545238.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYKRTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(24920..25936)
                     /locus_tag="ACL3G6_000664"
     CDS             complement(24920..25936)
                     /locus_tag="ACL3G6_000664"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HGR0545239.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            26148..26588
                     /locus_tag="ACL3G6_000665"
     CDS             26148..26588
                     /locus_tag="ACL3G6_000665"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0545240.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDK
                     IFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW"
     gene            complement(26711..27133)
                     /locus_tag="ACL3G6_000666"
                     /pseudo
     CDS             complement(26711..27133)
                     /locus_tag="ACL3G6_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(27195..27845)
                     /gene="phoU"
                     /locus_tag="ACL3G6_000667"
     CDS             complement(27195..27845)
                     /gene="phoU"
                     /locus_tag="ACL3G6_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGR0545241.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(27860..28612)
                     /gene="pstB"
                     /locus_tag="ACL3G6_000668"
     CDS             complement(27860..28612)
                     /gene="pstB"
                     /locus_tag="ACL3G6_000668"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR0545242.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(28614..29429)
                     /gene="pstA"
                     /locus_tag="ACL3G6_000669"
     CDS             complement(28614..29429)
                     /gene="pstA"
                     /locus_tag="ACL3G6_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGR0545243.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDIMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(29422..30285)
                     /gene="pstC"
                     /locus_tag="ACL3G6_000670"
     CDS             complement(29422..30285)
                     /gene="pstC"
                     /locus_tag="ACL3G6_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGR0545244.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(30403..31278)
                     /locus_tag="ACL3G6_000671"
     CDS             complement(30403..31278)
                     /locus_tag="ACL3G6_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HGR0545245.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(31445..32776)
                     /gene="pnpS"
                     /locus_tag="ACL3G6_000672"
     CDS             complement(31445..32776)
                     /gene="pnpS"
                     /locus_tag="ACL3G6_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system histidine kinase PnpS"
                     /protein_id="HGR0545246.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(32777..33484)
                     /locus_tag="ACL3G6_000673"
     CDS             complement(32777..33484)
                     /locus_tag="ACL3G6_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0545247.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(33568..34053)
                     /locus_tag="ACL3G6_000674"
     CDS             complement(33568..34053)
                     /locus_tag="ACL3G6_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HGR0545248.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            34039..34578
                     /locus_tag="ACL3G6_000675"
                     /pseudo
     CDS             34039..34578
                     /locus_tag="ACL3G6_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(34893..36584)
                     /gene="argS"
                     /locus_tag="ACL3G6_000676"
     CDS             complement(34893..36584)
                     /gene="argS"
                     /locus_tag="ACL3G6_000676"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HGR0545249.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            36720..37166
                     /gene="argR"
                     /locus_tag="ACL3G6_000677"
     CDS             36720..37166
                     /gene="argR"
                     /locus_tag="ACL3G6_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR0545250.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            37217..39751
                     /gene="mutS"
                     /locus_tag="ACL3G6_000678"
     CDS             37217..39751
                     /gene="mutS"
                     /locus_tag="ACL3G6_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HGR0545251.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            39898..41592
                     /gene="patA"
                     /locus_tag="ACL3G6_000679"
     CDS             39898..41592
                     /gene="patA"
                     /locus_tag="ACL3G6_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HGR0545252.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEVIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
BASE COUNT        12172 a         7913 c         9081 g        12559 t
ORIGIN      
        1 ggctagcttc ctagtttgca ctttgatttt cattgagtat aaaaagatct tgggtaacaa
       61 ctcaatttca gtagaaaagg aagtaaatct tcccacaata aaacgcatag tatcaagttt
      121 tttcaatacc tgatactatg cgtttttgct tttaacgact ttttgcccag tctcttattt
      181 ttcgataatt ttgtgggcga tcaattgacg gtaacaaatt tgtttattgt ttttattatc
      241 attaataatc tggagaatag tttcaaggga aacacgacca agctctaaac tattgatatc
      301 gacataggct gccaagttga gcttgggatt aaccgagtca aagctgagaa cagggacatc
      361 cagctggtgt ttggcaatat agttacaaac accttcagct aggaggctat cggttgtgat
      421 gatagcatca atttgtggat cgtgcttgaa taatcgcttg ctaaatttat agcccttttc
      481 ttccagaaac tcgtcggcaa agtagatgcg attgttgtca gtggtaagtt tgtaatgttt
      541 aagcgcctgt tcatagcctg ttaaacggtc tttggtcacg aagagctttt tacttcctcc
      601 gataaaggca atgcgtttgc agcctttttt gatgaaatat tcagtcgcat caaaaccagc
      661 ttgaacattg tcgttgtcga caagtgggat gaaaggagat agagatttac ctaagataag
      721 gaaggggaac tgttcttctg cgacgagttt tacgagaggg tcttcttctt gggcatagag
      781 aaagattagc ccatctacac gcttgccgta gaccatttgt gaaatagcgt tgagacgctc
      841 cttctcatct ttccctgttg ctatctgaat ggcatagtgg ttttcagatg cgacttgaga
      901 gatgccacgt agaaccgatg gaaagaaagg attctggtag aaggcgtctg agtcatcagg
      961 aagaactaat ccgataacct gagtatagct gcttaccaag ctacgagcgt tgaggtttgg
     1021 gtggtagttg agttccttca tagctttgcg aacgcgtttt tttgtttcgt cgctaatggt
     1081 tgatttattt tgaataacac gggttacggt tgaaggcgaa acaccagcag ccttggccac
     1141 gtctttaatc gtaacgggca taaaaatctc ctatttatgg taatttggat cacggaaatg
     1201 tgttttataa aagatagtga ccagatacag aacaaaaaga atattttgta cagtaatcag
     1261 ggttgtcata ttttggccaa ataatcccaa aataagtgta atcagagtcg gcaatcctaa
     1321 acagttcaag ataaagtgat agcactcttt aaaggttcta aatgaaaaga ggcgtgattt
     1381 cttagtgata taaaggagaa gactagctcc tagagagacg ataaagaaat tcaaaccaaa
     1441 gaggaagctc gcaccgagaa ctaggaagag gctgatatag acacgatttt gttggtacca
     1501 gtctttagaa attgcttggg tcaagctgtc tttgcttttg aaactctcag tctgaatggc
     1561 tcggtaagag atgcgggtca gttccttgct ttccttgctg atgactagct catttgtatc
     1621 gaaatgcagt tgcaagtcct taggtaattc cttgatttga cttggaccaa tcacaacaga
     1681 aggggcttga ctagctgttc cagtataagt taatgtgcca tcgacaattg tagcatgttc
     1741 agagagatcc tggacaacct catttgtcag aggttcatag acattatcga taaaagtttc
     1801 tagcggatag gtctcctggg agctgttttg gatagcaatg ggtaccatag acaagctgat
     1861 aaggaagata ctggtaaaga gaagttgaaa ccagttgagc tcgaaacgtt tggacagggg
     1921 cttacgaaac ccccaaatac ttgaaaaata ggaaaatgga tatggaagca taggtatctt
     1981 tctaaaaggt gttttctata tgagtattat tatatagaga aatgctcttt atttcaagtc
     2041 taggagaaaa attgcttgct acaaggatat tatttacagt gacaattgct aataatcaat
     2101 gaaaatcaaa gtgcaaacta gccacaggtt gctcaaagca caactttgag gttggagata
     2161 aagctgacgt ggtttgaaga gattttcgaa gagtataaaa tgaaaaaggg tggcggggat
     2221 aaattatccc ttgtcgccac cacttgtaag tcctgaaaca aagttctttt gtaggaagaa
     2281 gaagagaata cagattggaa gggcgatgag gatagcacct gctgagaagt aggcaatctt
     2341 caagtttttc gcattgttaa cgaaggtttg gagacctacg gcaacagtaa agtattcttt
     2401 ctcacgaagc aagaaactag agaggatgta gtccccgaaa ggtcccatga aggcccagag
     2461 agcttgtacg gcaaccattg ggcgaacaag tggtagaaca atttgccaga agcggcggaa
     2521 gtgtcctgca ccgtctagtt ttgcagattc gtctaaagac attggcactg tatcgaagta
     2581 gcctttcatg agccaagcat tcatcgggat accaccacca acgtagagga agatgaggaa
     2641 ccagttgtgg ttaagggcgt tcaacataag cgccataacg aagaaggctg tcaaagcggc
     2701 catagttggc accatttgga tgatcaagaa gaagaccaaa ctttgtttac gagccaagaa
     2761 gttgtaacgg ctgtaggcat aaccagcaag tacgatgata cttgtttgaa cagccatggt
     2821 aattaaggcg ataatcaaag tgttgaggta ccaagtaccg tacaaggttt cagtgaagag
     2881 gcctttaaag ttatcaaaat tgaggtcgat attagtatct agtttaaagg ctgagacgtt
     2941 acctgcttta aaggctgaca taatggtaat caacagtgga tagataatta caattgatag
     3001 accaatcagg taaaggtaag taaggctttg agtcagtcta cgtttgagtt taattgagtt
     3061 attcatctta gacgtcctcc atatcaaatg cgtgtagttt cttgaatgcg atcatagaga
     3121 ttgagatgac aatgatagag ataatcaagg taacagctgc cgccattgag tattgaggag
     3181 atgtacctgt tgtcaaacgg tagatccatg agatcaagat atcggttgaa ccagctccac
     3241 ctccgacact accaggtcct ccaccattga agaggtacat gatagagaag ttgttaaagt
     3301 tgaaggtgta ttggctaatc aaagtaggtg ccgcaacagc caaaatcatt gggaaagtga
     3361 tgttgcggaa tttttgccaa gcgttggcac cgtcaatata agctgcttcg taaaggtcgt
     3421 taggaataga ttgcaagata cccaaagtca aaacgtagat gtatgggaat ccgagccaac
     3481 cttgcatcat aatcaaggca atcttagtcc aagttgggtc tgttttccaa ggaataagag
     3541 ctccatcaag gaaaggaagg aatttagcca agattggcaa tacttgagtg ttgatagcac
     3601 cgacactatc gttaaacatg tttgagaatg tcaagatagt gatgaaggct gggacagccc
     3661 aaggaagaag gaaaataaca ccaaagatac gttttccttt gataaatggt tggttggcaa
     3721 tgatagctgt gaagatacca attacgattt gtaaagtaga agctgccaaa gcccaaatga
     3781 tagtccaaga aagaacagaa ccaaaggcag aacggaaggt actcaagctc caaatgtttg
     3841 taaagttggt caaaccaacc cagtccaaca acttgtttgg tggcaagtgt tggaagtcgt
     3901 agttggtaaa ggcgatcatc aaggttacga taactgggaa gataatcgcg aaggtcatgg
     3961 caacataaga tggaatgatc aagaggtaag ggaagccatt ttcataaatc cctttgatca
     4021 tgtctttgag tgtgcgtgga actggaattc cattgttaat gcgttttgca atcgtatgtg
     4081 catctttgat atttgagaaa taaaagagta cataaacgat tacaaagatt agatggaagg
     4141 caccacgaat cagcataaag agggaattat cacgacctgg tttgtcacca agagtgatga
     4201 ggttgctcaa ttcaggggtt gcaagtgcta ggaagtaaag gacaaatacg atggttacac
     4261 caaggaagat aaaacctttg gctttttgtt tattgtaaat ctgtcctaac ccaggaatga
     4321 tagacagcag ggctgcttta ctaggttgtt gcttttccat attaactcct ttcataggat
     4381 actacttttt tataagaaag ctaaattatt tgtgtctcta ttgataaatt caaaggggga
     4441 tttgatttcc accccccttg aacaaatttt ttattcacca aatttttgtt tgattgtttc
     4501 tttgatcaat gttacagcat cgttagcagc tgttttagca tctttttgac cacttacagc
     4561 atcaaagagc atatttttcg ctggatccca aactgcagac atttgagaga tgtttggcag
     4621 tggttgagtg ttcttgaact gtttgataac agctgttgtc aactcatcgt ttttaccttc
     4681 agcgtatgaa cgagcctcag tattagctgg gatttcgtta gtcttatcat ataatacttt
     4741 ttgttgttca gttgcaacaa ggaagtctac aaatttttga gaagcttcaa ggttcttaac
     4801 ggcttgagga atgacccaag ctttaccacc accgaatgca gcatattctt ttccatttgg
     4861 aagagttggg atagttgcaa ctccgtagtt tactttagca tctttaaagg cttgagcttt
     4921 ccaaggtccg tcgatgatag cagctgtttt accttcttgg aattgagttt ggattaagtt
     4981 tccagcacct tctgtatctt gcataccttt aggccatttt tcgtaccaag atttagcgta
     5041 gttgatacct gcgatagaac cgtcgtttgc aagaccgatg tctttagcgt ctttaccgtt
     5101 ttggccaaag acgtaagcac cgttaccggc aagaagtcca tatgtatagt agaagtttgt
     5161 ccagtcagct aggaaggcag tagttttacc atcttcacca gcgaatgcgt atttgctatc
     5221 tttagcaagg ttttccaagt cagcaaatgt ttttggagca tctttcacca agtctttgtt
     5281 gtagtacata acaagtgact cgataacggc aggagcaccg taaactttac cattagcagc
     5341 tgttacaaga gatttagttg tgtcgtctgt tttagcacca tcgctcaatt tcacttctga
     5401 aagttgtccg tcagaaccaa ggctacctac acggtcgtat ggagccatca taacatcagg
     5461 gacattacca gattggttgt caagagaaag tttatcaaga cctcctagag catcaccagt
     5521 tttaagagtg acttttactc cagcttcttt ttcataagct ttagcaacct cttcaatata
     5581 gctcttatat ccctcgtcta catatacagt gagttctttg acttcagatg aaccagaatc
     5641 agcaggctta tcagcagttt tgcttccgca agctaccaaa agcaagctag caagtgtagc
     5701 agttccaagc accgcagtgc tcttcataaa tttagatgac atagtgtatt cctcctaaag
     5761 aatagcaagt tttattgata aggaaacgca aacgttttcc tttatgagct tagtatagca
     5821 caaatagaaa acggttgcaa gtattttttg taaaaatttt aaaaaatttt taagcttgat
     5881 ttgatagtat aattttgcat tttaatagaa gaaaagtatg aaatagataa gaatacagta
     5941 tttttaataa aaatatatgg aatctgtcta aagagggaaa tcaggagggg tacctccctg
     6001 tttctaatct atatctattt tctatagacg tttgtgcttt gttgcatata aattcaagct
     6061 ccctaaggag gttttgtact ttgtatactg tctcgtgaga gtcaaacttt aggattagat
     6121 agttttaagt tatctttgct aaaatgagtt agtctcctta aaaataatca aaaaagtttt
     6181 ttaaaaacgc ttgcaattat gcttgaaaag gagtatactt ataagtaacg caaacgtttg
     6241 cgtctgaaaa atacgcaacg ttccattatt ttaacacacg aggtgctatt atgaaaaaac
     6301 gtcaaagtgg tgtgttgatg cacatctctt ctcttccagg agcttacgga atcggatcat
     6361 ttggtcaaag tgcttacgac ttcgttgatt tcttggtccg tacaaaacaa cgttactggc
     6421 aaatccttcc attaggagca actagttacg gggattctcc ttaccaatct ttctcagcct
     6481 tcgcaggaaa cactcatttt atcgatttag atatcttggt ggagcaaggt ttgttggaag
     6541 caagtgacct tgaaggagtt gactttggta gcgatgcgtc tgaagttgac tatgctaaaa
     6601 tctactatgc acgtcgtcct cttttagaaa aagcggtgaa acgtttcttt gaagtcggag
     6661 atgttaaaga ttttgagaaa tttgctcaag acaaccaatc atggcttgag ctctttgctg
     6721 agtatatggc tatcaaagag tattttgaca atcttgcttg gactgaatgg ccagatgcag
     6781 atgctcgtgc tcgtaaagct tcagcacttg aaagctatcg tgagcaattg gcagacaagt
     6841 tggtttacca ccgtgtgact caatacttct tcttccaaca atggttgaaa ttgaaagctt
     6901 acgctaacga caaccacatc gaaatcgttg gggacatgcc aatctacgta gcggaagatt
     6961 caagtgatat gtgggcaaat ccacatctct tcaaaacaga tgtcaatggt aaggctactt
     7021 gtatcgcagg atgcccacca gatgagtttt ctgtaactgg tcagctttgg ggtaatccaa
     7081 tctatgactg ggaagcaatg gacaaagacg gctacaaatg gtggattgaa cgcttgcgtg
     7141 aaagcttcaa aatctacgat atcgttcgta tcgaccactt ccgtggcttc gaatcttact
     7201 gggaaatccc tgctggttcc gatacagcag cacctggtga gtgggtgaaa ggtccaggct
     7261 acaagctttt tgcagccgtt aaggaagaac ttggtgagct aaacatcatc gcagaagacc
     7321 ttggcttcat gacagatgaa gtgatcgaat tgcgtgaacg tactggcttc ccaggaatga
     7381 agattcttca atttgccttc aacccagaag acgaaagcat tgatagccca cacttggcac
     7441 ctgctaactc agttatgtac acaggaacac acgataacaa tacggttctt ggttggtacc
     7501 gtaatgagat tgatgatgcg actcgtgagt acatggctcg ttacacgaac cgtaaagaat
     7561 acgaaacagt ggtacacgct atgcttcgta cagtattttc atcagttagc tttatggcaa
     7621 ttgcaactat gcaagattta ctagaattgg atgaggcagc tcgtatgaac ttcccatcta
     7681 cccttggtgg aaactggtct tggcgtatga ctgaagatca attgacacca gctgtcgagg
     7741 aaggtttgct tgacttgaca acaatttatc gccgaattaa tgaaaatttg gtagatttaa
     7801 agaaataaga caataatcag gagacaacta aacatgttat cactacaaga atttgtacaa
     7861 aatcgttaca ataaaaccat tgcagaatgt agcaatgaag agctttacct tgctcttctt
     7921 aactacagca agcttgcaag cagccaaaaa ccagtcaaca ctggtaagaa aaaagtttac
     7981 tacatctcag ctgagttctt gattggtaaa ctcttgtcaa acaacttgat taaccttggt
     8041 ctttacgacg atgttaaaaa agaacttgca gctgcaggta aagacttgat cgaagttgaa
     8101 gaagttgaat tggaaccatc tcttggtaat ggtggtttgg gacgtttggc tgcctgcttt
     8161 atcgactcaa ttgctactct tggtttgaat ggtgacggtg ttggtcttaa ctaccacttt
     8221 ggtcttttcc aacaagttct taaaaacaac caacaagaaa caattccaaa tgcatggttg
     8281 acagagcaaa actggttggt tcgctcaagc cgtagctaca aagtaccatt tgcagacttt
     8341 actttgacat caactcttta cgatattgat gttactggtt atgaaacagc gactaaaaac
     8401 cgcttgcgtt tgtttgactt ggattcagtt gattcttcta ttattaaaga tggtatcaac
     8461 tttgacaaga cagatatcgc tcgcaacttg actctcttcc tttacccaga tgatagtgac
     8521 cgtcaaggtg aattgctccg tatcttccaa caatacttca tggtttcaaa cggtgcgcaa
     8581 ttgatcatcg acgaagcaat cgaaaaagga agcaacttgc atgaccttgc tgactacgca
     8641 gttgtccaaa tcaacgatac tcacccatca atggtgattc ctgaattgat tcgtcttttg
     8701 actgcacgtg gtatcgatct tgacgaagca atttcaattg ttcgtagcat gactgcctac
     8761 actaaccaca caatccttgc tgaagcgctt gaaaaatggc ctcttgaatt cttgcaagaa
     8821 gtggttcctc acttggtacc aatcatcgaa gaattggacc gtcgtgtgaa ggcagagtac
     8881 aaagatccag ctgttcaaat catcgatgag agcggacgtg ttcacatggc tcacatggat
     8941 atccactacg gatacagtgt taacggggtt gcagcactcc atactgaaat cttgaaaaat
     9001 tctgagttga aagccttcta cgacctttac ccagaaaagt tcaacaacaa aacaaacggt
     9061 atcactttcc gtcgttggct tatgcatgct aacccaagat tgtctcacta cttggatgag
     9121 attcttggag atggttggca ccatgaagca gatgagcttg aaaaactttt gtcttatgaa
     9181 gacaaagcag ctgtcaaaga aaaattggaa agcatcaagg ctcacaacaa acgtaaattg
     9241 gctcgtcact tgaaagaaca ccaaggtgtg gaaatcaatt caaattctat ctttgatatc
     9301 caaatcaaac gtcttcacga gtacaaacgc caacaaatga acgctttgta cgtaatccac
     9361 aaataccttg acatcaaagc tggtaacatc cctgctcgcc caattacaat cttctttggt
     9421 ggtaaagcag ctccagccta cacaatcgct caagatatca ttcacttgat cctttgcatg
     9481 tcagaagtta ttgctaacga tccagcagta gctccacact tgcaagtagt tatggttgaa
     9541 aactacaacg ttactgcagc aagcttcctt atcccagcat gtgatatctc agaacaaatc
     9601 tcacttgctt ctaaagaagc ttcaggtact ggtaacatga aattcatgtt gaacggagct
     9661 ttgacacttg gtactatgga cggtgctaac gtggaaatcg ctgagttggt tggagaagaa
     9721 aacatctaca tcttcggtga agattcagaa actgttatcg acctttacgc aaaagcagct
     9781 tacaaatcaa gcgaattcta cgctcgtgaa gctatcaaac cattggttga cttcatcgtt
     9841 agtgatgcag ttcttgcagc tggaaacaaa gagcgcttgg aacgtcttta caatgaattg
     9901 atcaacaaag actggttcat gactcttctt gacttggaag actacatcaa agtcaaagag
     9961 caaatgcttg ctgactacga agaccgtgac gcatggttgg ataaagtcat cgttaacatt
    10021 tctaaagcag gattcttctc atctgaccgt acaatcgctc agtataatga agacatctgg
    10081 cacttgaact aatactcttc gaaaatctct tcaaaccacg tcagctttat ctgcaacctc
    10141 aaagcggtgc tttgagcaac ctgcggctag cttcctagtt tgctctttga ttttcattga
    10201 gtataagatg caaatttata ctaatacatt ttgtaaaaaa gcgagtttcg attgaaattc
    10261 gcttttttaa atgctgtgga tttgggtcaa tcttgtctaa aaatagggaa atcctagata
    10321 cagtgaaggc tttaaatgct ggtttttact gtcttcagcc ttatattttt tcgtagttgg
    10381 ttacctcata tctcttgtat tcgcttacat aaagtattat aatataattg taggaaagaa
    10441 ggtgttttta tgatatacac acttaaattg gtgttgttta ttacctttct tgtaataagc
    10501 ttgttacctg ataagatttt tggaaaaaat aaaaaaattt ggaaaatagt ttttgcaata
    10561 ttgacggcag tggcagcatt tatatttatg tactaagtta ttttaagaat gtagggaaat
    10621 aaaccctaca ttctttttag ttttttctgt tttctaaatt ctatttatcc aagcgcttca
    10681 acatttcttg cttcttcgct tcaagttctg cacgcttttc ttcgatttcg gcatgttttt
    10741 tctcgagttc agaacaactt gcaccattgc taaattcttt tcgccatcag gagatagggt
    10801 gagtcgacat gtctattact cacccaaagc agtcctacaa agcaggaatt ttctgttact
    10861 tttttggaaa tagtaacgtt tatacagctt tgacacttcg tatcaaagcg ccaaacacac
    10921 tccgagggat ttacagaaag cagaaaagga atgatctggt ataagatcat tccttttctc
    10981 tctttttctt taagtaatta tatacaatgt acgacgaagt cgtcattgca atgctgatcc
    11041 accacctaaa gggaacttta aacaacattg ataagataaa gaatataaac aacgaaaata
    11101 cgttataccc aattaatttt attgtatatc tcatgattaa aagttaatcc ttccgttgtt
    11161 aggaatggca tcatttttat cccataattg tgttaaataa gtccccggtg ataataaatt
    11221 catagcggat tctaaagcaa catcatttac aaaccaacta cctagatatc tagaaattgc
    11281 tgaacgaata gcactttttg ctgcatgttt tccttttact ttaattagat ttgcaaggcc
    11341 tgcagtagtt cctcctaatg ctaaagctat tgcagtatct aatagagcac ccatttgatt
    11401 aactgtaata ccttgccaag ctgctctaaa tggagagtat gtaggtggga ttgtataatc
    11461 gccttgtaat tgtcggttaa ttacttcttt gatccattgt tgtgagacgt ctggatgaaa
    11521 agattggatt tcgtttgcaa gtgtattgat ttgttcttct gttagagaag tgacaggttg
    11581 aagttccata tttgtttcaa tttgtgatac ttgttcagaa gcgtatacag ctgaaacact
    11641 tggaatcgct gatacaatta acacaattga cgtcaaaaaa accgaaataa atttcattaa
    11701 tttgttcatg agcttttctc ctttttattt gtatttgctt acattttatt atatactgtt
    11761 attatagtca agaaaaatat gctattatgt taaaaaaata tttttcaaaa tataaatgga
    11821 cggatttatt ttggattctt tttgtaattg gggcatgcct cttgacgggt aatagtagtc
    11881 ttttccccct tacccatcaa gaattctctt ttcgtggtag cgtttggggt ctggtactgg
    11941 ccttatatca cttattgttc attgataagt ttgtaatttc gaatcgaaaa taaaaattag
    12001 aactatgatt gactggctac ttttaatatt gattttggag gaagattttg tctctattat
    12061 ttattatttt aaatttatct attttgtaca agatttattc tttgagacgg gagaagtcga
    12121 aatacttgat ttatacggcc tatatcatat ttggggtaaa tgtagtatat ggtattcaat
    12181 ggttattaaa agaactgatt tcaactattt ccacttaata tgtatgaaaa ctataacaaa
    12241 acgcataaga ttaaggtttt taagcacctg ttcttatacg tttttgtaat attgaagatt
    12301 ttcggtaagt tttctacttt tgcgaagtct agtttagaat gctttcccaa ccaaaatctc
    12361 tgcttcgatg gtaatctctg tcagttggct ccagtcaatc ttgctctggt caacgtgaaa
    12421 gaggagagga gtcatactga gtagggcttg gagttgttct gctgtgatag tcttagtcag
    12481 agaggcagtt tgactagata ggatggtaaa gtgttcctgg aaatgctcct tgatatcttg
    12541 gttagaatac tccttgtttg tcagctggtc ctgtactctt tgacggattt ctttgaggtg
    12601 attttcagtt gggataacct ttatcaagat accgtctttg gataaaacgc gacgaaattc
    12661 tccatagttg gcaggtgaga agatatcaag cagaatatcc atgttagcgt cttttatagg
    12721 aagtcgtgcc aagtcgccaa cgaaccaatt gactgcccag ttgggttcac ttttagcagc
    12781 gatttggact gaatctttgg agatgtcaaa ggcatagaaa gttttttcag agtgactttc
    12841 ttgtagtttg cgagaataga atccttcacc acaaccgata tccaaaattg ttgtggtagt
    12901 ttttgagctt gcaagcaagt cagatacagc atctaagata gcttggtaaa agccggcttc
    12961 taggatttgt tgacggtttt gaaaattttc cttgtcatag ttagcagatt gcttgatttg
    13021 aggtgctaga ttgacatagc caaatttcgc caagtcaaaa gaatgacggt tgcagcactt
    13081 gaaattagtc tctaacagag tcagattttc ttgacagata ggacaggcaa aggcagtcgc
    13141 agaagcaaaa cgctgaagtt tgggcttgag atttgtattc atagtttaag tgtatcaaaa
    13201 gaggcaaatg aaagcaactt taggaataag tagatgggag attcagtaga aataaaacta
    13261 attctccaat ttatagaatg aaattgcttt tatatctaaa ttgctatata ataatgataa
    13321 ggaggaaata agtatgttaa aagaagtatt aaccgttgca aaagttgcga aaaaatcttc
    13381 attatttttg ggtggtgtcg catttggtac ccttggtttg aaaatcttag caagtaagga
    13441 agctaaaaaa ggttattcta aagctttggc taaggcttac aagttgaaag acgagctaga
    13501 tgcatctgtt tctgttgtga agcaacatgg agacgatgtc ttgcaagatg ccaaatattt
    13561 gtacgagcaa gagaaaaaag aagagcaatt agatagcctt ataggtgaat aatatgtctt
    13621 ttaaagtgct acatagagga taccaacata tccgactatc atcttctttt tcacttacct
    13681 tggatattca agactatctt cgttccttgg cgagagatga aaaggggatt gagtctatcc
    13741 agttttacat ggatcaacag cactttactc tacgcataaa agaaggcttt tctgtattag
    13801 ataatgcaga agccttttta aaaagaattg ataaagggaa agtttctgag ttgatgactc
    13861 ttcccattcg tagagaagag agtgcttatt ctattgtttc aggtgcagcg gttaagcgtg
    13921 tactttttcg tagttttgtg ccgtatccta ttcgctatat atggacttgt tatcaggctt
    13981 tgggttatat tagagaagcc tatcaaacac tagcgcgtaa ggaactaacg atggaagtct
    14041 tggactgttc ggctatttta ttgtccttgt ttatgaacca atccaagaca gctagcaata
    14101 tcatgtttat gcttgatttg gggaatcatt tagatcagtg gtccttgaaa aaaactgcaa
    14161 cagatttaga acagagtctt cttgcaaaag agagcgatgt attcctagta cagggcgata
    14221 cggttgttag tataaagagt tccgatgttc aaataggaga tgtcttgatc ttatctcaag
    14281 gaaatgaaat tctgtttgat gggcaagtag tttcaggttt aggtatggtc aacgaaagtt
    14341 ccttgacagg agagagtttt ccagttgaaa aaagagagtc tgatttggtt tgtgcaaata
    14401 cagtattaga aactggagag ttacgcattc gtgtaacaga taatcagatg aacagccgta
    14461 ttttacagct gattgagttg atgaagaaat ctgaagaaaa caagaaaacg aaacaacgct
    14521 atttcatcaa gatggcggat aaagtcgtca aatataattt cttgggggct gggctgactt
    14581 acctattgac aggttctttt tctaaggcta tttctttcct attggtcgat ttctcctgcg
    14641 ctttgaaaat ctctactcct gtagcttatt tgacagttat caaggagggg ttgaaccgtg
    14701 aaatggtgat taaggatgga gatgttctgg agaaatatct ggaagttgat actttcttgt
    14761 ttgataagac aggaacaatc acaactagtt atcctatagt tgaaaaggtg ttaccttttg
    14821 gagactatag tgaggaagat attctcagaa tcagtgcctg tcttgaggaa cacatttatc
    14881 atcctattgc taatgccatc gtcaagcaag ctgagataga gggaattgaa catgaggaaa
    14941 tgcatgggaa actccaatat atcgcaagca aggggatcaa atctcatata gatggccaac
    15001 cagttcttat tgggaattat gtcttgatgc aggatgagca gattcatatc agttcagaac
    15061 aaaatgcttt aattgaagag tacaagagtc actacaatct cttattcttg gcttatcaaa
    15121 atgaattgat tggaatgttc tgcattcata ctcctttgag aaaagaagca aaaacagcct
    15181 tggataaact taaggcacag gggaaaaaat tgattctggc aacaggagac accttgatta
    15241 ggacagagga attagtcaaa gatttgccct ttgatcaggt ctatacagac ttgaaacctg
    15301 atgggaaatt tgagttagta gagaaactgc agaaagcagg tcacactatt ttgatggttg
    15361 gagatggctt gaatgactca gcggctttaa ctctatcaga tatcggtgtg gtgatgaatg
    15421 agagtgcaga tatttctaag cagatgagtg atatcttatt gttagataat cgtttggatt
    15481 tcttccaaga gttggattcg ttatcatcat ctttgcaaac actcatcaag aaaaatattc
    15541 aggataccgt tgtcgtaaat agtagtttga ttggctttgg cttatttaat tggttcagtc
    15601 cttcaaatct ctctatctta cataatctaa caaccttgcg cattgtcctg cgtagcctgt
    15661 ctattaaaaa tagatagatg agagttatta acagcaaaaa ggagttacct ttctcgaggt
    15721 taactccttt gtttatagat aaatgttgaa tagtttagta agtcaataca aagtattttt
    15781 tcttcccacg acggataaca gtcagttcat tttctaactt atcagcgtca ctcaagacat
    15841 agtcaaggtc ttggatgcgg tcgccgttta cgtagatggc tccgttttgg acgtcttcac
    15901 gggcttggcg ttttgagtta actataccag atgagacgag cagttccacg atattgttgt
    15961 tttcgtctgc ctgtacttgg tagtttggca caccacgaag tccttgtttg agctctttga
    16021 cagaaaggtt tttgatgttt cctgcaaaga gttgctcagt gatgttaagt gcttctttgt
    16081 aggcttcttc tccgtgaaca agtgtaacaa cttcacgagc caagactttt tgagccaagc
    16141 gttcgtgtgg cgctgcttca aattgtttac gaatatcttc aatctcatca agtgacaaga
    16201 aagtaaagat tttcaagaag cgaacagcgt cagcgtccat cacgttcatc cagaattggt
    16261 acatttcgta tggagaagtc ttttcgggat tgagccagac ggcatttcct tctgatttac
    16321 caaatttctt accagttgca tctgtgatta gtggaacagt gataacgtga ccagtcttgt
    16381 ccgccttacg acgaagcaat tcggtaccag ctgtcatatt tccccactgg tcagaaccac
    16441 cgatttgaag agtgacatta tggtcttggt taaggacgaa gaagtcgtac ccttgcatga
    16501 tttggtaagc gaactcagtg taagaaattc ctgtttcgat ccgtttttta acagattcct
    16561 tactcatcat gtagttgacc gtgaagtatt ttccaatatc acggaggaag tcaatgaagc
    16621 tgatgctgcc aaaccagtcg tagttgttga ccatgacagc cttgttttcg ccattttcaa
    16681 agtcaagaaa acgagaaagt tgtccttgga tagacttgac ccagccatct actgtgtctt
    16741 ttgtttggag actacgttca gcatctttga aggacggatc tccgatgaga cctgtagcac
    16801 cgccaacgag cgcataaggt ttgtgacctg ctagttgcaa gcgacgactt gtcaagattg
    16861 cgacaaggtg gcctaggtga aggctgtcag cagttggatc gtagccagta tagtaagaaa
    16921 cttgaccttc ttctagggct ttacgcaaag cttcttcatc agtcgtttga aatatcaaac
    16981 cacgctcttt tagctcatca aaaatgtgca tgtgtctttt ctccttttta aaattattgt
    17041 ttctacctat tgtatcacaa acttgggcaa tagcctagca gaatagggaa gaaagtggct
    17101 attttattga aaatttccct tttgtggtat aatagataaa gtgaggaaat ccatgcaaaa
    17161 tcaattaaat gaattaaaac gaaaaatgct ggaatttttc cagcaaaaac aaaaaaataa
    17221 aaaatcagct agacctggca agaaaggttc aagtaccaaa aaatctaaaa ccttagataa
    17281 gtcagccatt ttcccagcta ttttactgag tataaaagcc ttatttaact tactctttgt
    17341 actctgtttt ctaggaggaa tgttgggagt tgggattgct ttggggtacg gagtggcctt
    17401 atttgacaag gttcgggtgc ctcagacaga agaattggtg aatcaggtca aggacatctc
    17461 ttctatttca gagattacct attcggacgg gacggtgatt gcttccatag agagtgattt
    17521 gttgcgcact tctatctcat ctgagcaaat ttcggaaaat ctgaagaagg ctatcattgc
    17581 gacagaagat gaacacttta aagaacataa gggtgtagta cccaaggcgg tgattcgtgc
    17641 gaccttgggg aaatttgtag gtttgggttc ctctagtggg ggttcaacct tgacccagca
    17701 actaattaaa cagcaggtgg ttggggatgc gccgaccttg gctcgtaagg cggcagagat
    17761 tgtggatgct cttgccttgg aacgcgccat gaataaagat gagattttaa cgacctatct
    17821 caatgtggct ccctttggcc gaaataataa gggacagaat attgcagggg ctcggcaagc
    17881 agctgaggga attttcggtg tagatgccag tcagttgact gttcctcaag cagcattttt
    17941 agcaggactt ccacagagtc ccattactta ctctccttat gaaaatactg gggagttgaa
    18001 gagtgatgaa gacctagaaa ttggcttaag acgggctaag gcagttcttt acagtatgta
    18061 tcgtacaggt gcattaagca aagacgagta ttctcagtac aaggattatg accttaaaca
    18121 ggacttttta ccatcgggca cggttacagg aatttcacga gactatttat actttacaac
    18181 tttggcagaa gctcaagaac gtatgtatga ctatctagct cagagagaca atgtctccgc
    18241 taaggagttg aaaaatgagg caactcagaa gttttatcga gatttggcag ccaaggaaat
    18301 tgaaaatggt ggttataaga ttactactac catagatcag aaaattcatt ctgccatgca
    18361 aagtgcggtt gctgattatg gctatctttt agacgatgga acaggtcgtg tagaagtagg
    18421 gaatgtcttg atggacaacc aaacaggtgc tattctaggc tttgtaggtg gtcgtaatta
    18481 tcaagaaaat caaaataatc atgcctttga taccaaacgt tcgccagctt ctactaccaa
    18541 gcccttgctg gcctacggta ttgctattga ccagggcttg atgggaagtg aaacgattct
    18601 atctaactat ccaacaaact ttgctaatgg caatccgatt atgtatgcta atagcaaggg
    18661 aacaggaatg atgaccttgg gagaagctct gaactattca tggaatatcc ctgcttactg
    18721 gacctatcgt atgctccgtg aaaagggtgt tgatgtcaag ggttatatgg aaaagatggg
    18781 ttacgagatt cctgagtacg gtattgagag cttgccaatg ggtggtggta ttgaagtcac
    18841 agttgcccag cataccaatg gctatcagac cttagctaat aatggagttt atcatcagaa
    18901 gcatgtgatt tcaaagattg aagcagcaga tggtagagtg gtgtatgagt atcaggataa
    18961 accggttcaa gtctattcaa aagctactgc gacgattatg cagggattgc tacgagaagt
    19021 tctatcttct cgtgtgacaa caaccttcaa gtctaacctg acttctttaa atcctactct
    19081 ggctactgca gattggattg ggaagactgg tacaaccaac caagacgaaa atatgtggct
    19141 catgctttcg acacctagat taaccctagg tggctggatt gggcatgatg ataatcattc
    19201 attgtcacgt agagcaggtt attctaataa ctctaattac atggctcatc tggtaaatgc
    19261 gattcagcaa gcttccccaa gcatttgggg gaacgagcgc tttgctttag atcctagtgt
    19321 agtgaaatcg gaagtcttga aatcaacagg tcaaaaacca gggaaggttt ctgttgaagg
    19381 aaaagaagta gaggtcacag gttcgactgt taccagctat tgggctaata agtcaggagc
    19441 gccagcgaca agttatcgct ttgctattgg cggaagtgat gcggattatc agaatgcttg
    19501 gtctagtatt gtggggagtc taccaactcc atccagctcc agcagttcaa gtagtagttc
    19561 tagcgatagc agtaactcaa gtactacacg accttcttct tcaagggcga gacgataatt
    19621 ctctaaatga agtggccaat caatggattg ccactttttt cttttcgtgt tacaataagg
    19681 gtatgaatca gtatcagaaa aagattgtta acggaaaaat ttattcgctc ctatccggct
    19741 taatatgggg aatctgtgga attttaggag agtacttctt tactcattat caggtgtctt
    19801 cgggctggat tacctctatg cgtttgacac tggcagggag tcttgtactc atttggtctg
    19861 caatacaatt aaaatcgcaa gtgctagata tttggcgaga caagaaaaat tacctgccct
    19921 ttttagccta tgctattttg gggatttttt cagttcagta ttttttctat ctctgtgtag
    19981 aatactcaaa tgctacgaca gcaactattt tacagtttat tagccctgtc tttatcctct
    20041 tttacaatcg cttggtttat caaaaacgag cgtcaaaaag cgctgttttc tatgttttgg
    20101 ttgccatgct gggtgtttgc ttgatggcga caaagggaga cctctctcag ttatccatga
    20161 cgccgctagc tcttataaca ggtttgctga gtgccatggg tgttatgttt aatgttatct
    20221 tgccccaacc ttttgctaag cgttatggtt ttgttcctac ggttgggtgg gggatgattt
    20281 tggcaggttt gtttagcaat gtcctctcgc cggtttatca gctttccttt actcttgata
    20341 tttggagtat cttgatttgc ctcattatcg ctttctttgg aacggctttt gcttttttca
    20401 tttccatgaa ggctgtgtcc ttggtttctc ctttggtggt tgccgttatc agtgccagtg
    20461 aacctctctc ttctgctctc ttgagtgttt tgttcttagg attagtagtg gattggtccc
    20521 tccttctagc tatagccttg attattttac ccatgatatt tttgtctata gaagaagcga
    20581 aagaaagtag ataaaaagtc ttttcttaat tctaaaagtg tgctatactg gaatagtcaa
    20641 taaaacacgg ggagatagtt gtgaagagtg tttttaggtt gtatcggtag gggcttgctt
    20701 ttaccgacag cacgttttat ctcacatccc taaaaaatca tacctaaaaa cagacaaaaa
    20761 ggtttcaaat ttgaggcctt ttttggtaga ataggtatca ttataacgaa ccaggaggca
    20821 cctatgactg ctacaaaaat gaacgctcaa gaaattatcc aatttatcgc caatgctgaa
    20881 aagaaaacca gtgtcaaagt aacctttgag gggcaactcg caactgctgt gcctagctct
    20941 gttgtcaaac taggaaatgt cctattcgga gactggaagg acgtggctcc gcttcttgaa
    21001 ggtttggtag aaaatcaaga ttatgttgtc gagcaagatg ctcgtaattc tgcagttcct
    21061 ttgctagata agcgtgctat caacgctcgt atcgagccag gtgctattat ccgtgaccag
    21121 gtggaaattg gtgacaatgc tgttatcatg atgggagctg ttatcaatat cggtgctgaa
    21181 atcggtgctg gaaccatgat tgacatgggt gccatccttg gtggccgtgc cattgttgga
    21241 aaaaatagcc acgttggtgc aggtgcagtt ttggcaggtg tgattgagcc agctagtgct
    21301 gaaccagtcc gtgtcggaga caatgttctc atcggggcta atgcagtggt tatcgaagga
    21361 gtccaaatcg gtagtggttc agttgtcgca gcaggagcta ttgttaccca agatgtccca
    21421 gaaaacgtgg tagtagcagg tgttccagct cgtattatca aagaaattga tgcccaaact
    21481 caacaaaaaa cagcgctaga ggatgcgctt cgtaccttgt aattgtaaaa gtaaaaaaga
    21541 ggcggaaccc tttttccagc ctctttctgc tatatcggag gacagataga tgttagattt
    21601 gattcagact agacgagatt tacaccagat tccagagatt ggcttggagg agttcaagac
    21661 tcaggcttat ttgctggatg tgattgagaa attgactacg ggcaaggatt ttgttcaaat
    21721 tcgtacttgg cggacaggga ttttggtcta cctgcaggga agtcagccgg agcgaaccat
    21781 tggttggcgg acagatattg atggcctgcc tatcgtcgaa caaacaggtc taccttttgc
    21841 ttctcaacac caaggtcgca tgcatgcctg tggtcatgat tttcatatga ccattgcctt
    21901 aggctgtctt gagcgcgccc ttgaggagca acccaagaat aatctgctct ttctatttca
    21961 gcctgctgaa gaaaatgaag ctggtggtat gctcatgtat gaggacgatg cttttggaga
    22021 ttggttgcca gatcaattct atggtctcca tgttcgtcca gatttgaaag tcggccagat
    22081 tgcgactaat actcatacac tctttgcagg aacttgcgag gtgaagatcc gtttcaaagg
    22141 caaaggtggc cacgcagctt ttcctcatga agccaatgac gccttggtgg cggctagtta
    22201 ctttgtgacc caagtgcagt cagttgttag ccgcaatgtc aacccaatcg agggagcagt
    22261 ggtgaccttc ggcgtttttc aagctggaac caccaacaat gtcatcacag acacagcttt
    22321 tttacatgga actattcgtg ccttgacaca ggacatgagt ctcttggtgc aaaagagggt
    22381 aaaaacagtt gcagaagggg ttgcagctgc ctttgatatg gaagtcgaag tggaactcaa
    22441 acaaggtgga tacctacctg ttgagaacaa tccagccttg gcgcgtgaac tgatggactt
    22501 ctttgacgag aaagacggaa tcgagttgat tgatatcgaa cctgctatga caggcgagga
    22561 ctttggttat ctcctttcaa aggttgatgg cgtgatgttt tggctaggta tcgatagtcc
    22621 ctacgctctt catcaccctc aaatgagtcc taaggaagaa gtcttagcta ttggggtggc
    22681 tgcggtgtct agtttcctga aaaagaaggc agcagaatag agggcttgtc tatgaaatcg
    22741 gaattacgca agcaagtctt gcatgaaatg aaggctatat ctcaagagca aaaacaggct
    22801 atagaccaag ctttaaccga gcggctttta caccatccct tctaccaaga agccaaggtc
    22861 atcgcaacct acctctcttt ttctcatgag tttcaaacgc gggaactgat tgagcaggcg
    22921 ctgaaggacg gcaagaaggt tttaataccc aaaacttatc ccaaggggcg catggagttt
    22981 gtggcctatg atccgcaaca gttggtaaaa acttcctttg ccttactgga gccacaggga
    23041 gatgtggaag tggtggatgc atctcagatt gatttgattc atgttcctgg tctggctttt
    23101 acgacgaaag gatatcggat aggatacggt ggaggctatt atgaccgcta tctggaacat
    23161 ttttctggtc gtactttgag tacgatatat ccttgtcaaa ttcaggactt tatacctgaa
    23221 aaccatgata ttcctgttca ggaggtatta attgatgaag gaaatctttg atagacgtta
    23281 ccctgtgacg agtttcttcc tcttagtgac ggccttggta tttttactaa tgttggtcac
    23341 tgcaggcgga aactttgaca gggcagatac attatttcga tttggagcca tgtatgggcc
    23401 agctattcgc ctctttcccg agcaggtttg gcgtctcttg tctgccattt ttgttcatat
    23461 tgggtgggaa catttcattg ttaatatgct ttcactttat tatcttggaa ggcaggtaga
    23521 ggagattttc ggttctaagc agtttttctt tctctatctt ttatcaggaa tgatgggcaa
    23581 tctctttgtt tttgtattta gtcctaaatc cttagcagca ggcgcctcta cctctcttta
    23641 tgggctattt gccgcgatta ttgttcttcg ctatgcaact cgcaatcctt atatccaaca
    23701 gctagggcaa tcctatctga cactttttgt ggttaacatt attggaagtg ttctgattcc
    23761 aggaatcagc ctagcaggcc atatcggtgg tgcagttggt ggcgcatttc tagcagttat
    23821 ctttccagtt agaggagaaa aacggatgta taacaccagc cagagattag gagcggtagt
    23881 cttgttcgta ggactcgcca ttttgctttt ctacaaggga atgggaatgt gacgaagttg
    23941 aaagaaaatt tgtgtaatga aaaaagataa ggcatttttt gaaccttatc tttttatttt
    24001 attccttctc agtcaattct tttccaagtt ggatgaggta attcttcaaa tcatctttga
    24061 cttgtggatg tttgagggcg tagtcaatag atgttttcat aaagccaaac ttatccccaa
    24121 cgtcgtaacg agctcctgta aattcacggg caaaaacacg ctgtgtttta ttaagagtat
    24181 cgattgcatc agtaagttgg atttcatttc cagcaccagg agcttggttt tcgaggattt
    24241 ggaaaatttc aggcgtgagg aggtagcgtc cgataatagc aaggtcgcta ggagcgtcct
    24301 ctggagctgg tttttcaaca aaggtttcaa cactgtaaag accatctttt ccttcgcctt
    24361 gcggagcaat aaccccgtaa gcagatactt cgtcatgagg gactggcatg acagcgatag
    24421 tagacgcgtg ggtacgcttg tagtcatcca tgagttgttt ggtaagtgga acagcctttt
    24481 cgtctgtgat atccatcaag tcatcaccaa gcataacgac aaaaggttca tttccgacga
    24541 aagccttggc ttgcaaaaca gcatctccga gaccgcgtgg atgagtttgg cggataaaat
    24601 gcagacgcat gccagttgtt tcatcaacta gcttcaaaag atctgttttc cctttttctt
    24661 tgaggttata ttccaattcg aagtttgaat cgaagtggtc ctcaatagaa cgttttgatt
    24721 taccagtgac aactagaata tcttcaatac ctgatttgag agcctcttcc acgataaact
    24781 ggatagttgg tttgtctacg attggcaaca tttctttggc aagggccttg gttgctggta
    24841 aaaatcgagt tcctagtcca gcagcaggga taactgcctt tctaactttt gatgtcataa
    24901 aaatcctttc tatagagggt taagaccact cattttctgc tttaaattca ttgttcatga
    24961 tgtcataaat ggcatctttg atattggttc cgtgataaat aacttggtaa atagcctgtg
    25021 taatgggcat atagactcca agttcttggg ctagttcata ggctgctcga gtcgttgaaa
    25081 ttccttcgat taccatgccc atattagctt ctatatcagc tagggattct cctcgtccga
    25141 gagcatctcc agctctccag ttacgagagt ggatggaagt tcccgttacg atcaaatctc
    25201 ccacaccaga taagccgcta taggtcaatg gactggcccc gagtgctacc cctaggcggg
    25261 tgatttctgc taaacctcga gcgatgatgg ctgccttagc attatcacca aatccaagac
    25321 catgtaaagc tccagcaccg acagcaataa tatttttaag agcaccagca gtttcaaccc
    25381 cgataacatc cgtattggta taaagtcgga agtagtgatt actaaatagc tcctgaacgt
    25441 attgagctgt ttgtaaatct ttagaagcag cagttattaa agttaggtca cgcacaatgg
    25501 tctcttctgc atgactaggc cctgaaacaa cgacgatatc actacggaga tgttcaggaa
    25561 tttcttcttc aagaatggtt gataatcgtt tatggctatc aggttctaat ccctttgatg
    25621 cgtgcatgat gataacctta tggtccaagg tttgtgcaac ttgctgggca acaagtcgtg
    25681 tcacttttgt tgggacaaca aacaaaatcg catccacatt tttcaatgtt tctgctaagt
    25741 cggtgtaggc aatgatattt tcgtctagaa cgacatcttt aaagtagtgc ttattagtat
    25801 ggtgtgtatt aatttcattg atttgctcgg gaagatttcc ccaaatacgt acctcgtgtc
    25861 cattgtcatt taagacttgt gaaagggcgg ttccccaaga accaggcccc aagacggcga
    25921 cggtttgttt ttccatgatt tcctccttga tagatttctt tctcttattc tatcatattc
    25981 taggggattt tgcacttgca ttactggggt atggtggaaa aatacacaaa gaccgagatg
    26041 aagggataaa ctcttagtct ttagttaaag tgagaagaaa tctgatagat agtttgattc
    26101 agtatatgct tataatagag gtaaacaact caggaagttc ttgtaggttg cgagagtttg
    26161 gcgaaaaaat taaaagatta cgtttggcta aaaaaatcag tcgttcagaa ttttgtggtg
    26221 atgagtctga attaagtatc cgtcaattaa ttagaattga aaatggagaa tccagaccaa
    26281 cactaacaaa gttaaaatat attgctgaac gtttggaggt tgaagattac aagttgatgc
    26341 caagttatat agagttggat aaggaatacc tagaattgaa gtatttcttg atgaggactc
    26401 ctacatacga agatgaaact atcgcccaaa agaaagagag tgtttttgat aagatttttg
    26461 aagagtatta tgataggcta cctgaggaag aaagatttat catcccaaat tattcatatc
    26521 tagcactagc gaactacaca gttcaaaaat taccagaaaa gctagttgaa atactgtcct
    26581 tctggtgatt ttgcttaatt tctgatgttc gagacatgat tgaggagatt tgtcttgatt
    26641 ttttcctaaa aaagggcaga ctcctccctt ggtttgatgc tcgattttta aaataaggtg
    26701 acttattctg ttaggcagtt ttcccctgcc ctctagctct atatggaaca gggagtatca
    26761 gatttatctg gcagattgta tcaaataagg cttgaaactg ttttgaatag gcgtatagac
    26821 ttgagaattt gagaatatgt cgtctagcag tagagacata ttttccggca atatgaagga
    26881 agagacgtcg aaaacgcttg atagtcaagg cctttacttc atcaccagct agctgcttta
    26941 aaaagaggta gagattataa gccagacagc ccatcatcat acgtacttca ttcttaatca
    27001 tggtcgaact atctgtctta tccccaaaga atcctgcttt cctttctttg ataaagtttt
    27061 cagcattccc tcgttcacga tagaattgaa acagctcctc actatctaca ctgcttaaat
    27121 tggtcaaatg aactttttta caaccataaa aaagagcact taatcgtact cttctctttt
    27181 aaggattagt tgaattaatt caaatccact agttctcctg tttctaggta gactaggcgt
    27241 tcacaaatgt tagcaatgta atcagcgaag cgttccagat gccctatgat ataaaggtat
    27301 tgagttccat tgggaattga ggtttcttgg tctttcataa gtccaatgat ttcctttgat
    27361 aaggcataat aatattggtc aatctgttca tctttttgag caatactaat agcttttgag
    27421 gcttggtgca aaggaaaggc aaccaataaa tcggctagca tgctgaggga taatttaccc
    27481 atttggtgta actgttcttc gtcaggggct agttgatttt cttttagttg caaaacagct
    27541 ttggcaatgc ctgccatatg gtctcccata cgttcaaggt ctgaacaaga agacatgatg
    27601 ctaatcacaa atcgaaggtc agacacttgt ggctgctgca aggccaacaa acgggcacag
    27661 gtcaattcga tagcgctttg accttggttg atagcatgat ccttattgat aattagctct
    27721 gccatctcct tgtctttgga ggctaaggcc agtaaggctt ttgaagctgt ttcaaggaca
    27781 agttgcccta gtcctaaaaa ggattgttct aattcatgca attctaagtc aaattgattt
    27841 ctcataggtt tttccttcct tatccgaacc gtcctgaaat atagtcttct gtgcgctgat
    27901 cttttggatt ggtaaacacg tcaacggtat ctccaaattc gcaaatttct cctgttaaga
    27961 aaaaagcagt tttatctgaa atacgtgaag cttgttgcat gttatgggta acaatgataa
    28021 tcgtataatc cttttttagt tgctgaatga ggtcttcaat ttttaaagtg gagatagggt
    28081 ctaaggctga agtcggctca tccattaaca gaatatcagg ttctactgct aaagctcgcg
    28141 caatgcaaag gcgttgctgc tgaccgccag ataaggacat agcactcttt ttaagatcat
    28201 ctttgacttc ttcccaaatg gctgcccctt ttaaagattt ctccactaag gcatctaatt
    28261 gttttttgtc tcgaatacca tgtgtccttg ggccataagc cacgttatca tagatagaca
    28321 tggcaaaggg attaggctgt tgaaaaacca tccctacacg cttacgtagc tgattaaggt
    28381 tgaatttgct actataaata tcttgctcat ctaagaggac ttggccttca atatggcaag
    28441 aaggaaccaa atcgttcatc cggttaaggg tttttagaaa agttgatttg ccacaaccag
    28501 atgggcctat caaggcagta atctgtcttt ctggtaattg aatcgaaata ttttttaagg
    28561 cttgaaaatc cccgtaaaat aagtctaggt gtctgactga aaatgttccc atactaggaa
    28621 gctcctttca caagttttcg agataataag cttgatagag tatttatcat taaaacagta
    28681 ataatcaaaa tcacaccggt agcataggct tcattgacat gtagcccctc acttgacagc
    28741 atatacatat gcagggctag agaacgacct gaagacatga gactacttgg cgtattggta
    28801 gaggtaccta atgtatacat gagggcagct gtctcaccaa cgatacggcc aatagctagt
    28861 atcactccag ctaaaatacc tggcatggca actggtagaa caattctaaa aacagtccgt
    28921 aacttacctg ccccaagtcc ataacttgct tgacgcatga tatcactaac agataaaagg
    28981 gcttcttctg ttgagcgaat aatgactggc aacaccatga tgactgaggt taagattcct
    29041 gataacagag agtattgaaa acctaagaag actacaaaga agagcatgcc aaacagacca
    29101 aaaacaatgg aaggaatccc agacaaggta tctgaggcca atcgcatgat tttaacacaa
    29161 agggaatctt tttttgtata ttccacaaga taaaaaccag caaaaatccc tatgggcaag
    29221 gctaaaagaa gagcaccaaa gaccagaata acggtggaaa taatcgctgg cataagggaa
    29281 atgttctcag aagtataagt ccaagaaaag agggatagac ttagatgagg taagcctttg
    29341 atgaggataa aaccaatgat taaaaagaga gagccaaagg ttaaagctga aaaacaataa
    29401 acaagaagtt ttagcaggta tttactcata agatgatttt cctttcaagt aggcaaagta
    29461 ggcattaatc aagagaataa ggaaaaagag aactgctgag gttgcaataa gggcttccct
    29521 atgctgacct gatgcgtaag ccatttccag aacaatattg gttgttaagg ttctggttcc
    29581 tgaaaagagt ccacttggaa taatcggctg gttgcctgcc accaaaataa ctgccatggt
    29641 ttcacctact gcgcgaccga tgcctaaaat aactgctgat aaaataccag atctcgcagc
    29701 tggcaagatg acactaaaaa tactccgttc atgactagct cctagagcca agctaccaga
    29761 ataatacgtt ttgggaactg ttcggatagc agattctgac aaactgataa tggttggcaa
    29821 aatcattatt cctaatagta acgaagcggt taggacactc atgccatttc ctaaaaagct
    29881 tctaatccaa ggcaccaata attgtaggcc gaaaaaacca taaacaatag atggaatggc
    29941 cgccatcaag ttgatagctg attttaagaa gccatagacg ggctttggac aataataaac
    30001 cataaacacc gatgtcaaga tgcctgttgg caccccaatc acaatcgctc ctaaggtaat
    30061 taataaggaa ccaacgatca ttggtaaaat accatagctt gccggaatgt tcgttggcga
    30121 ccaatcactg cctaataaaa aacgggcaaa gccgtagtta gccatgaaag gtaagccatt
    30181 actaaaaata aagaaacaga ttagcaaaat agctacaaca gctactgttg cactcatgaa
    30241 aaaaattgcc ctaaaaactg cttctttgaa ggcttgtttt atcacatctt gtcctttcta
    30301 gtgaagaaag taagggagat acgacacctc cctacttgcc ttctttatct tattgtacga
    30361 tgaaacgtct gcatctcttt agagatttat ggagcaaaca ttttatttaa tcttgtccca
    30421 ggtggttaat ttgccactaa aaacgtctgc aagttcagcc atactgactt ggcttgcctt
    30481 attgtcatta ttgaccacaa cagcaatacc gtctaaagca atagcatcat gggtgagact
    30541 cttaccttct tcaggagtta attccctaga aaccatacca atatcagcgg ttttctcctt
    30601 aacagcggta atacctgctg aagacccatt agaggtaata tcaatcgtaa cttctggatt
    30661 ttctttttta taagcttctg ctaatttttc cattaaagaa gatactgaag tggaacctac
    30721 aacagacaac ttgcctgata agtgttggct tgtatattct gtggtttcag ttttagcttc
    30781 aataaattta ttatctgtga ccacttgttg accttgtttg gagtggataa agctgataaa
    30841 atcttgacct agcttggaaa gattagaaga ccaaacaatg ttgaagggac gttgaagagg
    30901 gtattcacca tctaaaactg tgtctcgact agccttgaca ccatcaatct ctaaagcctt
    30961 gacagatttc gttaaagatc ccaaggagat gtagccgata gcattagcat tcccttgaac
    31021 tgctgagaga acaccttctg tactattttg aatcacagct gttttggcag tgttgtcaat
    31081 ttttttatca ccgtcttttt tgagaatccc tgtgatttct gtgaaggcac cccgtgttcc
    31141 agagccattt tctcgtgaaa tcacctcaat cgttcctgaa gctgactgtt tggaagcagc
    31201 tgactgattg ccacaggcaa caagcccaaa tcctgataag ccaatggctg caagagtaag
    31261 catttttttg aatttcataa taatcacctt tatctctatg tatttttctt gtgtaggctt
    31321 actacattta tagtctaaca agtctttgta aaggtttatc cctgattcat gtaaagattg
    31381 tgtaaagaat caaaaaaagc cacttttgaa aaagggctgc tcctaaaaat agctttaaaa
    31441 attattagtc ctgtgcgaaa gattggttag gaagaaaaat cgtgaagcaa ctgcctctgc
    31501 caagctgact tgtcaccgtg acttggccac ctaataattg actgagttct ttgacaatgg
    31561 caaggccaag accagtgcca ccagtttgtc tgcttcgacc tttattaact cggtaaaaac
    31621 gttcaaaaat acgatcctgc tctaattgac taataccaat ccctgtatct gatacagaaa
    31681 tcttaatgcc ttcgttcacc ttttgggtct tgacctcaat ttttccccct tgttcagtgt
    31741 aacggatggc attggataaa agattgagta agatttggga aagtaattga ctatctgata
    31801 cgagggtgac atcatctggc acctgcacct ttagctgtaa atccttcttc ttgagctgag
    31861 gttgcaagct ttgagtcaaa tcctgtacaa attcagccaa agaaagggtc gtccattgta
    31921 taggcatttg ttgagcctta gataaggtaa gaagatgctc aacaatatgc tcaagacgca
    31981 aactttcttt gtaaataatg tctagaaagt catccttgag cgcttcttct tcagctgaca
    32041 tccccttaat ggtttcagca aagcccttaa ttgaagtaac tggtgtcctc aattcatggg
    32101 aggcatttga gacaaaggct aaatttaact tttcataagt tctaatcgtt gttaaatcat
    32161 atagcaagac gagcacagct tccacagatt gggtggggct aaaaacggga actgctgtca
    32221 cttctaaaat caagtcaccc tcatgaaacc cacttacttc ttgttttaac cttgtttttt
    32281 gatcaaaggc ttggtgaact aaattccgaa tatccatccg tttgaggtca tcaagtgaac
    32341 ttatgtcgcc gtccacatcg ggaaaataat gaggcagaga gcgactggat aataacatct
    32401 gaccttgagc ggaaactaaa aacgtcccca tggttaggtg cgacagaaga acctccattg
    32461 tttcggctag gtccttgtat tgctgatcct gttgggagac tttggttttt aggccagaca
    32521 catactgagc caaagacttt aagtcttctt gccctttttc taaaaagtat tcactactgg
    32581 tcaagagagg ttggtgcaag gtctcaaaag caacttccca tttccaaagg caaaagagcc
    32641 agtagccacc ttgtcccaaa gaaagggcta gaagaaagag accgatgcct ttactgatcc
    32701 aagttaatgc catccctgca atcagaatga ggctaacact tagattgact agccaaaatt
    32761 gaaggtagcg tttcatctat aactccttga acttataacc ataaccccga atggttcgaa
    32821 taaattgagg ggctttagga ttgtcttcaa ttttttccct caacttacca atatgaacgt
    32881 ccaccaaacg tgtttcctgc ccaaagtcat acccccagat acgttccaaa agacgctctc
    32941 tagtcagtgt catgttggga tgtttcataa gatagagcaa gagttcaaat tcttttgggg
    33001 tcaaactcag taacttattc gccttgtaga cttcatgacg ctcagggtat actttcaagg
    33061 tcccaaatag ccaagaatcg tcagcgatat tatctgaatc atctccttct tgttctcctt
    33121 tagttcgcct gaggacagcc ttgacacgcg ccagcaattc tctagggcta aaaggcttgg
    33181 tcaggtagtc atcagcccct aattccaagg ccaaaacctt atcaaattca tcacttttcg
    33241 cagaaaccat cataattgga gttttgacgc ctttggctct cagccgctta caaacttcca
    33301 tgccatctaa ttgtggtaac atgatatcaa gcaagataaa atcaaagggt tctgtttctg
    33361 ccaaagctaa ggccttccgt ccatttgtta ccaattgagt agaaaagcct tccttactta
    33421 aatggtagtc aagcaatttc agaatgtgtt cttcatcatc cactaataag acttgttttg
    33481 tcatctatta tctcctattg gtaacattat aacacaatta tcagaaatcc taacattgct
    33541 aaatcagatt aaatttgcct atcaagacta gtatctggtc aaacgctcaa tcatctcctt
    33601 gtgctctgga taggtcgcca gtagatctac cctttcaaat aattcaaaat cctcaaattc
    33661 aaaaccagga gcaacaagac aagaaaccag agcatcatcc ttatcaactg ttgatcccca
    33721 aatagtgccc ttaggaacac agtagtgaag ttgttgccct ttggatatgt ccaggcctaa
    33781 agtgactgct tcgtagtgac catctgctgt aatcatgtga acagtaagtg gggatcctgc
    33841 atgaaaatac cagatttcat ctgctgtcaa tcggtgaaaa tgtgaaggat tcgtttcttc
    33901 taataagaaa taaatactgg tataaagcgc ccttccctta ccagcaaggt ttatagtgtc
    33961 tgaagctttt tttgtttgtc taaaatagcc accttcaaca tggggagcta actctagagt
    34021 tcttatcaag tcttctttat ccgtcggagc caatgggttg aagtaactct tgttcaaagt
    34081 ggttttacga tttcaagaac tcctctcagt tctgaggaca cggtaatgat tgatgcgacg
    34141 gaagtaaaaa tcaatcgccc taaaaaaaga attagcgaat gattctggta aaaagaaatt
    34201 tcacgctatg aaggctcaag cgattgtcac aagtcaaggg agaattgttt ctattgccat
    34261 gatatgaagt tgttcaaaat gagttgcaga aatatcggaa aagctggtaa aatcttggct
    34321 gacagtgatt atcaagggct catgaagata tatcctcaag cacaaactcc acgtaaatcc
    34381 agcaaactca agccgctaac agctgaagat aaagcctgta accatgcgct atccaaggag
    34441 agaagcaagg ttgagaacat ctttgccaaa gtaaaaacgt ttaaaatgtt ttcaacaacc
    34501 tatcgaaatc atcgtaaacg cttcggatta cgaatgaatt tgattgctgg tattatcaat
    34561 catgaactag gattctagtt ttgcaggaag tctattattt ggttaggtga attagtgaag
    34621 tgtttaggca agtgtctctg gttacgacgt catggcctct aaatcgatta tatttagggg
    34681 tcatgactag tgaagcagtt agctagttcg catataagcg gctagcgtct aacaattagg
    34741 aactttagtt ccaataactt taagattacg acgttttagg acataaatcg atcatattta
    34801 tgtcctaaaa ctagtgaagc gcctagccaa agtccgaata ggatttggcg ttagttactt
    34861 agattgcttt gcaatcaagt aactttggcg atttacatct tctctggcgc ttctactcca
    34921 agcaagcgaa gggcttcttt gagaacgact gcggttgcgt agctgagggc tagacggctg
    34981 tcgcgttctg ggctttcatc caagatacgt gtatgtgcat agtatttgtt aaaggattga
    35041 gccaggctaa ttgcaaattt agcaatgata gaaggttcaa agttatctgc cgcacggttg
    35101 ataatacgtg ggaagtcttg aatgagttta atgatttccc agctttcagt atcattcaag
    35161 ctatagttgc cagctgtttc tggtttgaaa tcggctttgc gtaagataga ttggatacga
    35221 gcgtaggcat attgaacgta aggtccagtt tcaccctcga aggataccat agcttctagg
    35281 tcgaagtcgt atccatttgt acggtcagtt ttgaggtcat agaatttaat ggctccaacc
    35341 ccaacagcat gtgctacttg gtctttgttt tctagttcag gatttttagc ctcgatttgg
    35401 accttggcac ggctaacagc ctctgcaaca gtaggctcta gcaagatgac attcccttta
    35461 cgagtagaga gcttcttccc ttcttttgta accagaccaa aaggaacgtg ggtaatgtcg
    35521 tcactccaat cgtagcccat ctcttgcaag acagctttga gttgtttaaa gtgggcagat
    35581 tgctcttgac caacgacgta gatagattta gcaaattggt attcattttt acggtagagg
    35641 gctgcagcca agtcacgtgt gatatagaga gttgcaccat cagacttctt gatgagggct
    35701 ggatgttcaa ttccatattt ctcaagattc acaacttggg caccttctga ttcaagaagt
    35761 agtccttttt cagaaagaat gtctacaact gcatccatct tatcattgta gaaggcttct
    35821 ccgttatagc tgtcaaattc aaccttcaat tcattgtaaa ggcggttaaa ttccactaaa
    35881 ctttcatcgc ggaaccattg ccaaagagcg agagcttcct catctccatt ttcaagttta
    35941 cggaaccatt cgcgcgcttc ttcatccaag ctagggtcat tttcagcttc agcgttgatg
    36001 cggacataga gtttaaggag ttcatcgatt ggatgagctt ttacagcttc ttcgtcgccc
    36061 cattttttgt aggcaacaat caacatccca aattgtttac cccagtctcc caaatggttg
    36121 accttgaccg tttgataacc gattttttgg aaaatatgtg acaagctatc tccgataaca
    36181 gttgaacgca ggtggccaat agaaaatggt ttagcgatat tcggactaga catgtcgata
    36241 acaacatttt cttgtttgcc aatattttgg tcagcatagt gttctttttc agtggtaaca
    36301 gcttgcaata cttgagcaga aatggcagat ttatcaagga aaaagttaac gtaaggtcct
    36361 gttgcgacaa ctttttcaaa ggcttggctg ttcatttttt cagccagttc agccgcaatc
    36421 atttgtggtg ctttacgttc gacttttgca agagaaaaag cagggaaagc aatgtctccc
    36481 atttctgagt ttttaggggt ttccagtaac tttaaaatag cctcttggtc caggctatca
    36541 atgatgctag ataattcgct agcaatcaat tcttttgtat tcattaagag ctcctttttg
    36601 gacttttcta ctattttatc acaattttaa agaaagaaga aaaaattttt gaaatctcct
    36661 gtttttttgg tataatatgg ttataaatat agttataaat atgcacgcaa gaggatttta
    36721 tgagaaaaag agatcgtcat cagttaataa aaaaaatgat tactgaggag aaattaagta
    36781 cacaaaaaga aattcaagat cggttggagg cgcacaatgt ttgtgtgacg cagacaacct
    36841 tgtctcgtga tttgcgcgaa atcggcttga ccaaggtcaa gaaaaatgat atggtgtatt
    36901 atgtactagt aaatgagaca gaaaagattg atttggtgga atttttgtct catcatttag
    36961 aaggtgttgc aagagcagag tttaccttgg tgcttcatac caaattggga gaagcctctg
    37021 ttttggcaaa tattgtagat gtaaacaagg atgaatggat tttaggaaca gttgctggtg
    37081 ccaatacctt attggttatt tgtcgagatc agcacgttgc caaactcatg gaagatcgtt
    37141 tgctagattt gatgaaagat aagtaaggtc ttgggagttg ctctcaagac ttatttttga
    37201 aaaggagaga cagaaaatgg cgatagaaaa gttatcaccc ggcatgcaac agtatgtgga
    37261 tattaaaaag caatatccag atgctttttt gctctttcgg atgggtgatt tttatgaatt
    37321 attttatgag gatgcggtca atgctgcgca gattctggaa atttccttaa cgagtcgcaa
    37381 caagaatgcc gacaatccga tccctatggc gggtgttccc tatcattctg cccaacagta
    37441 tatcgatgtc ttgattgagc agggttataa ggtggctatc gcagagcaga tggaagatcc
    37501 taaacaagca gttggggttg ttaaacgaga ggttgttcag gtcattacgc cagggacagt
    37561 ggtcgatagc agtaagccgg acagtcagaa taattttttg gtttccatag accgcgaagg
    37621 caatcaattt ggcctagctt atatggattt ggtgacgggt gacttttatg tgacaggtct
    37681 tttggatttc acgctggttt gtggggaaat ccgtaacctc aaggctcgag aagtggtgtt
    37741 gggttatgac ttgtctgagg aagaagaaca aatcctcagc cgccagatga atctggtact
    37801 ctcttatgaa aaagaaagct ttgaagacct tcatttattg gatttgcgat tggcaacggt
    37861 ggagcaaacg gcatctagta agctgctcca gtatgttcat cggactcaga tgagggaatt
    37921 gaaccacctc aaacctgtta tccgctacga aattaaggat ttcttgcaga tggattatgc
    37981 gaccaaggct agtctggatt tggttgagaa tgctcgctca ggtaagaaac aaggcagtct
    38041 tttctggctt ttggatgaaa ccaaaacggc tatggggatg cgtctcttgc gttcttggat
    38101 tcatcgcccc ttgattgata aggaacgaat cgtccaacgt caagaagtag tgcaggtctt
    38161 tctcgaccat ttctttgagc gtagtgactt gacagacagt ctcaagggtg tttatgacat
    38221 tgagcgcttg gctagtcgtg tttcttttgg caaaaccaat ccaaaggatc tcttgcagtt
    38281 ggcgactacc ttgtctagtg tgccacggat tcgtgcgatt ttagaaggga tggagcaacc
    38341 tactctagcc tatctcatcg cacaactgga tgcaatccct gagttggaga gtttgattag
    38401 cgcagcgatt gctcctgaag ctcctcatgt gattacagat gggggaatta tccggactgg
    38461 atttgatgag actttagaca agtatcgttg cgttctcaga gaagggacta gctggattgc
    38521 tgagattgag gctaaggagc gagaaaactc tggtatcagc acgctcaaga ttgactacaa
    38581 taaaaaggat ggctactatt ttcatgtgac caattcgcaa ctgggaaatg tgccagccca
    38641 ctttttccgc aaggcgacgc tgaaaaactc agaacgcttt ggaaccgaag aattagcccg
    38701 tatcgaggga gatatgcttg aggcgcgtga gaagtcagcc aacctcgaat acgaaatatt
    38761 tatgcgcatt cgtgaagagg tcggcaagta catccagcgt ttacaagctc tagcccaagg
    38821 aattgcgacg gttgatgtct tacagagtct ggcggttgtg gctgaaaccc agcatttgat
    38881 tcgacctgag tttggtgacg attcacaaat tgatatccgg aaagggcgcc atgctgtcgt
    38941 tgaaaaggtt atgggggctc agacctatat tccaaatacg attcagatgg cagaagatac
    39001 cagtattcaa ctggttacag ggccaaacat gagtgggaag tctacctata tgcgtcagtt
    39061 agccatgacg gcggttatgg cccagctggg ttcctatgtt cctgctgaaa gcgcccattt
    39121 accgattttt gatgcgattt ttacccgtat cggagcagca gatgacttgg tttcgggtca
    39181 gtcaaccttt atggtggaga tgatggaggc caataatgcc atttcgcatg cgaccaagaa
    39241 ctctctcatt ctctttgatg aattgggacg tggaactgca acttatgacg ggatggctct
    39301 tgctcagtcc atcatcgaat atatccatga gcacatcgga gctaagaccc tctttgcgac
    39361 ccactaccat gagttgacta gtctggagtc tagtttacaa cacttggtca atgtccacgt
    39421 ggcaactttg gagcaggatg ggcaggtcac cttccttcac aagattgaac cgggaccagc
    39481 tgataaatcc tacggtatcc atgttgccaa gattgctggc ttgccagcag accttttagc
    39541 aagggcggat aagattttga ctcagctaga gaatcaagga acagagagtc ctcctcccat
    39601 gagacaaact agtgctgtca ctgaacagat ttcactcttt gatagggcag aagagcatcc
    39661 tatcctagca gaattagcta aactggatgt gtataatatg acacctatgc aggttatgaa
    39721 tgtcttagta gagttaaaac agaaactata aaaccaagac tcactagtta atctagctgt
    39781 atcaaggaga cttctttgac aattctccac ttttttgcta gaataacatc acacaaacag
    39841 aatgaaaagg agctgacgca ttgtcgctcc cttttgtcta ttttttaagg agaaagtatg
    39901 ctgattcaga aaataaaaac ctacaagtgg caggccctgg cttcgctcct gatgacaggc
    39961 ttgatggttg ctagttcact tctgcaaccg cgttatctgc aggaagtctt aggcgccctc
    40021 cttactggga aatatgaagt tatttatagt atcggggctt ggttgattgg tgtggccgta
    40081 gtcggtctag ttgctggtgg actcaatgtt gtcctcgcag cctatattgc ccaaggagtt
    40141 tcatccgacc ttcgggagga tgccttccgt aaaattcaaa ccttttctta tgctgatatt
    40201 gaacaattta atgcgggaaa tctagtcgtt cgaatgacaa atgatatcaa ccagattcag
    40261 aacgttgtca tgatgacctt ccaaattctt ttcagacttc ccctcttgtt catcggttcg
    40321 tttatcctag cggttcaaac cttaccttct ctgtggtggg tgattgttct catggtagtc
    40381 ttgatttttg gtttgactgc tgtcatgatg ggaatgatgg ggcctcgttt tgctaaattt
    40441 caaacccttc ttgagcgcat caatgccatt gccaaggaaa atttacgtgg cgttcgtgtg
    40501 gtcaagtcct ttgtccaaga aaaagagcaa tttgctaagt ttacagaggt ctcagacgag
    40561 cttcttggtc aaaaccttta cattggttat gccttttcag tagtggaacc ctttatgatg
    40621 ttggttggtt acggggcggt cttcctctct atttggctgg tcgcgggaat ggttcagtcg
    40681 gatccgtctg ttgttggttc catcgcttct tttgttaatt acctaagcca gattatcttt
    40741 accattgtta tggttggatt tttgggaaat tctgtcagcc gtgccatgat ttccatgcgt
    40801 cgtattcgag aaattcttga cgcagagcca gctatgacct tcaaggatat cccagatgaa
    40861 gagttggttg gaagtcttag ctttgaaaat gtgaccttta cctatccaat ggacaaggaa
    40921 ccgatgctga aagatgtgag ctttactatt gaacctggtc aaatggttgg tgtagttgga
    40981 gcgactggtg caggaaagtc aaccttggct caattgattc cacgtctctt tgatccacag
    41041 gacggggcca ttaaaatcgg tggcaaggat attcgagaag tgagtgaagg aaccctgcgt
    41101 aaaacagttt ccatcgttct ccaacgtgcc attcttttta gtggaacgat tgcagataac
    41161 ttgagacagg ggaaggggaa tgctactcta tttgaaatgg agcgcgcagc caatattgcc
    41221 caggctagtg aattcattca tcgtatggag aaaacctttg aaagtccagt tgaagaacgg
    41281 ggaaccaatt tctctggtgg acaaaaacaa aggatgtcga ttgcgcgtgg gattgtcagc
    41341 aatccacgta ttctgatttt tgacgattcg acctcagcct tggatgccaa atcagagcgc
    41401 ttggtgcaag aagctttgaa taaggacttg aaggggacga caaccattat tattgctcaa
    41461 aaaattagct cggttgtcca tgcagacaag atcttggttc taaatcaagg acgattgatt
    41521 ggtcaaggca cgcatgcaga cttggttgcc aacaatgccg tttaccgtga aatctatgaa
    41581 acacagaaat gaaagacaaa ctataagaaa agtcaatagt tttatctaaa ctatttctta
    41641 tttcaatttg atgatttggc gatgatttta gagcacggca aaaagccctt gaaaaagtcc
    41701 attttttcaa aggtaatcct gtgtt
//
LOCUS       DBEJKC010000013        40414 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.013, whole genome shotgun sequence.
ACCESSION   DBEJKC010000013 DBEJKC010000000
VERSION     DBEJKC010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 40414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40414
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.013"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            222..452
                     /gene="blpU"
                     /locus_tag="ACL3G6_000680"
     CDS             222..452
                     /gene="blpU"
                     /locus_tag="ACL3G6_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HGR0545253.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            455..580
                     /locus_tag="ACL3G6_000681"
     CDS             455..580
                     /locus_tag="ACL3G6_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGR0545254.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKKFLKSSEKKTEKSVKK"
     gene            1167..3320
                     /gene="comA"
                     /locus_tag="ACL3G6_000682"
     CDS             1167..3320
                     /gene="comA"
                     /locus_tag="ACL3G6_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter ComA"
                     /protein_id="HGR0545255.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLFSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNSLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGSVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            3333..4682
                     /gene="comB"
                     /locus_tag="ACL3G6_000683"
     CDS             3333..4682
                     /gene="comB"
                     /locus_tag="ACL3G6_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence pheromone export protein ComB"
                     /protein_id="HGR0545256.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQSEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQFFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4852..5559
                     /gene="purC"
                     /locus_tag="ACL3G6_000684"
     CDS             4852..5559
                     /gene="purC"
                     /locus_tag="ACL3G6_000684"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGR0545257.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIVG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5561..5704
                     /locus_tag="ACL3G6_000685"
     CDS             5561..5704
                     /locus_tag="ACL3G6_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGR0545258.1"
                     /translation="MFATENLRLSTKRTQAEKVPQTFSLCRELGELTDVYEIVWEKLQ
                     GLK"
     gene            5761..9486
                     /locus_tag="ACL3G6_000686"
     CDS             5761..9486
                     /locus_tag="ACL3G6_000686"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HGR0545259.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFTQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVCVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEAANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9579..11021
                     /gene="purF"
                     /locus_tag="ACL3G6_000687"
     CDS             9579..11021
                     /gene="purF"
                     /locus_tag="ACL3G6_000687"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HGR0545260.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDSLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            11058..12080
                     /gene="purM"
                     /locus_tag="ACL3G6_000688"
     CDS             11058..12080
                     /gene="purM"
                     /locus_tag="ACL3G6_000688"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HGR0545261.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            12077..12622
                     /gene="purN"
                     /locus_tag="ACL3G6_000689"
     CDS             12077..12622
                     /gene="purN"
                     /locus_tag="ACL3G6_000689"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HGR0545262.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12706..13215
                     /locus_tag="ACL3G6_000690"
     CDS             12706..13215
                     /locus_tag="ACL3G6_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGR0545263.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            13240..14787
                     /gene="purH"
                     /locus_tag="ACL3G6_000691"
     CDS             13240..14787
                     /gene="purH"
                     /locus_tag="ACL3G6_000691"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HGR0545264.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDATYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14909..16171
                     /gene="purD"
                     /locus_tag="ACL3G6_000692"
     CDS             14909..16171
                     /gene="purD"
                     /locus_tag="ACL3G6_000692"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HGR0545265.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKTFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            16362..16853
                     /gene="purE"
                     /locus_tag="ACL3G6_000693"
     CDS             16362..16853
                     /gene="purE"
                     /locus_tag="ACL3G6_000693"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HGR0545266.1"
                     /translation="MTKPIISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTP
                     DLMFKHAEEAYSRGIKVIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYS
                     IVQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSN
                     ELI"
     gene            16840..17931
                     /gene="purK"
                     /locus_tag="ACL3G6_000694"
     CDS             16840..17931
                     /gene="purK"
                     /locus_tag="ACL3G6_000694"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HGR0545267.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPVSRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEVD
                     LEAAYALAESADCVLEEFVNFALEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVAENPSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            17941..18168
                     /locus_tag="ACL3G6_000695"
     CDS             17941..18168
                     /locus_tag="ACL3G6_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGR0545268.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            18231..19529
                     /gene="purB"
                     /locus_tag="ACL3G6_000696"
     CDS             18231..19529
                     /gene="purB"
                     /locus_tag="ACL3G6_000696"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HGR0545269.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19584..23522)
                     /gene="strH"
                     /locus_tag="ACL3G6_000697"
     CDS             complement(19584..23522)
                     /gene="strH"
                     /locus_tag="ACL3G6_000697"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored beta-N-acetylhexosaminidase StrH"
                     /protein_id="HGR0545270.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKADVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYDDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKIISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAVTHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQEEDIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKVLPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(23835..24551)
                     /locus_tag="ACL3G6_000698"
     CDS             complement(23835..24551)
                     /locus_tag="ACL3G6_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0545271.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIEFISCDRDH"
     gene            24899..26686
                     /locus_tag="ACL3G6_000699"
     CDS             24899..26686
                     /locus_tag="ACL3G6_000699"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HGR0545272.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYIAWNLHEPREGEFHFDGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEERGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            26683..27159
                     /locus_tag="ACL3G6_000700"
     CDS             26683..27159
                     /locus_tag="ACL3G6_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0545273.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            27187..28092
                     /locus_tag="ACL3G6_000701"
     CDS             27187..28092
                     /locus_tag="ACL3G6_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR0545274.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            28079..28894
                     /locus_tag="ACL3G6_000702"
     CDS             28079..28894
                     /locus_tag="ACL3G6_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0545275.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            28901..29305
                     /locus_tag="ACL3G6_000703"
     CDS             28901..29305
                     /locus_tag="ACL3G6_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0545276.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            29604..30764
                     /locus_tag="ACL3G6_000704"
     CDS             29604..30764
                     /locus_tag="ACL3G6_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000903564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGR0545277.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATILVSFARSGNSPESVATVDLAKSLVDELYQVTITCATDGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEY"
     gene            30886..31923
                     /locus_tag="ACL3G6_000705"
     CDS             30886..31923
                     /locus_tag="ACL3G6_000705"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGR0545278.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSITPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPVGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            32130..32984
                     /locus_tag="ACL3G6_000706"
     CDS             32130..32984
                     /locus_tag="ACL3G6_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0545279.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKEELLTIVQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            33134..33391
                     /locus_tag="ACL3G6_000707"
     CDS             33134..33391
                     /locus_tag="ACL3G6_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HGR0545280.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(33559..33795)
                     /locus_tag="ACL3G6_000708"
     CDS             complement(33559..33795)
                     /locus_tag="ACL3G6_000708"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545281.1"
                     /translation="MKIKVQTRKLAAGCSKHCFKVVDGTDEVSSKHCFEVVDRTDEVS
                     NHIYGKVKLMWFEEIFEEYKFLHNKTHITKVLMN"
     gene            complement(33849..34082)
                     /locus_tag="ACL3G6_000709"
     CDS             complement(33849..34082)
                     /locus_tag="ACL3G6_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGR0545282.1"
                     /translation="MDVREAHEFQAGHAPGAKNLPLSTLEQGYKELKPDHEYYVICQG
                     GVRSASTCQFLSSQGLTVTNVEGGMNTWPGQVE"
     gene            complement(34135..34317)
                     /locus_tag="ACL3G6_000710"
                     /pseudo
     CDS             complement(34135..34317)
                     /locus_tag="ACL3G6_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691454.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            34366..35130
                     /locus_tag="ACL3G6_000711"
     CDS             34366..35130
                     /locus_tag="ACL3G6_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HGR0545283.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            35743..37122
                     /locus_tag="ACL3G6_000712"
     CDS             35743..37122
                     /locus_tag="ACL3G6_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGR0545284.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIASRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            37136..37801
                     /locus_tag="ACL3G6_000713"
     CDS             37136..37801
                     /locus_tag="ACL3G6_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HGR0545285.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            37936..38094
                     /locus_tag="ACL3G6_000714"
     CDS             37936..38094
                     /locus_tag="ACL3G6_000714"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545286.1"
                     /translation="MKIKDQTRKLAAGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NIYTARRR"
     gene            38156..38695
                     /locus_tag="ACL3G6_000715"
     CDS             38156..38695
                     /locus_tag="ACL3G6_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0545287.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            38762..39172
                     /locus_tag="ACL3G6_000716"
     CDS             38762..39172
                     /locus_tag="ACL3G6_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HGR0545288.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            39288..>40414
                     /gene="pavB"
                     /locus_tag="ACL3G6_000717"
     CDS             39288..>40414
                     /gene="pavB"
                     /locus_tag="ACL3G6_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HGR0545289.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADG
                     LNPTPGQVLPEETPGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     SPSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALSPLG"
BASE COUNT        11170 a         7838 c         9448 g        11958 t
ORIGIN      
        1 tcatgaacta ggattctagt tttgcaggaa gtctaatagt aaaaaagtga ttagaaaaca
       61 tcttttttaa aaatagagat gattttgaaa caaaaaagct aattcaagac gtttcgatgc
      121 caattcaaga tttggatgaa aaaaattaat agatactgtt atactaaact tgtcaagttt
      181 gtaacaagac aaatattaaa aataaaaaag aggtattcgt tatgaataca aaaaagatgt
      241 cacaatttga aattatggat actgagatgc ttgcttgcgt tgaaggtggc ggatgcaatt
      301 ggggagattt tgccaaagca ggtgttggag gaggagcagc acgaggtctt cagctaggaa
      361 ttaaaacaag aacatggcaa ggtgcagcaa ctggtgctgc gggaggagct atacttggag
      421 gtgtggccta tgcagcgaca tgttggtggt aattatggat tttaaaagtt ttattattgg
      481 tttagtagtt ggtatatttg gtccttatat ggatgattta attagaaaaa aatttttaaa
      541 gtcttcggag aagaaaacag aaaaatctgt taaaaaataa tcaaaactat aaatgatgaa
      601 tctgaatcaa aattattttg cgcatgtaaa gaggagtctt atagtaacga gtcaaaaaag
      661 gagtaactat gaatcgtaat ttagaacggt gttatctatt ctgactagga atagatcata
      721 ccagaggtag cttagaaata gcagagacat tagaaattga agtaataaat gggatgtcgt
      781 aagtgttact atcaatgatt tatttgtttc aagcttgcct agggtgacag taaaaaatca
      841 atttcctttc aatagcatat ttttagtggg caggactctt gttctgccta tttttttatc
      901 caaaaagtgc agttgggagg gagataggct catttgggaa ggaagtccag tttttgttta
      961 gtgattgggg taagatagtt gttatcagat gagtttatac tcttcgaaaa tcaaattcaa
     1021 accacgtcaa cgtcgccttg ccgtatatat gtgactgact tcgtcagtcc tatctacaac
     1081 ctcaaaacag tgttttgagc agcctgcggc tagtttccta gtttgctctt tgattttcat
     1141 tgagtattag ggaaaaggag atgaatatga aatttgggaa acgtcactat cgtccgcaag
     1201 tggatcagat ggactgcggt gtagcttcat tagccatggt ttttggctac tatggtagtt
     1261 attatttttt ggctcacttg cgagaattgg ctaagacgac catggatggg acgacggctt
     1321 tgggcttggt caaggtggca gaggagattg gttttgagac gcgagccatt aaggcggata
     1381 tgacgctttt tgacttgccg gatttgactt ttccttttgt tgcccatgtg cttaaggaag
     1441 ggaaattgct ccactactat gtggtgactg ggcaggataa ggatagcatt catattgccg
     1501 atccagatcc cggggtgaag ttgactaaac tgccacgtga gcgttttgag gaagaatgga
     1561 caggagtgac tctttttatg gcacctagtc cagactataa gccttataag gaacaaaaaa
     1621 atggtctgct ctcttttatc cctatattag tgaagcagcg tggcttgatt gccaatatcg
     1681 ttttggcaac actcttggta accgtgatta acattgtggg ttcttattat ctgcagtcta
     1741 tcattgatac ctatgtgcca gatcagatgc gttcgacact agggattatt tctattgggc
     1801 tagtcatcgt ctacatcctc cagcaaatct tgtcttacgc tcaggagtat ctcttgcttg
     1861 ttttggggca acgcttgtcg attgacgtga ttttgtccta tatcaagcat gtttttcacc
     1921 tccctatgtc cttctttgcg acacgcagga caggggagat cgtgtctcgt tttacagatg
     1981 ctaacagtat catcgatgcg ctggcttcga ccatcctttc gattttccta gatgtgtcaa
     2041 cggttgtcat tatttccctt gttctatttt cacaaaatac caatctcttt ttcatgactt
     2101 tattggcgct tcctatctac acagtgatta tctttgcctt tatgaagccg tttgaaaaga
     2161 tgaatcggga taccatggaa gccaatgcgg ttctgttttc ttctatcatt gaggacatca
     2221 acggtattga gactatcaag tccttgacca gtgaaagtca gcgttaccaa aaaattgaca
     2281 aggaatttgt ggattatctg aagaaatcct ttacctatag tcgagcagag agtcagcaaa
     2341 aggctctgaa aaaggttgcc catctcttgc ttaatgtcgg cattctctgg atgggggctg
     2401 ttctggtcat ggatggcaag atgagtttgg ggcagttgat tacctataat accttgctgg
     2461 tttactttac caattctttg gaaaatatca tcaatctgca aaccaagctt cagacagcgc
     2521 aggttgccaa taaccgtcta aatgaagtgt atctagtagc ttctgagttt gaggagaaga
     2581 aaacagttga ggatttgagc ttgatgaagg gagatatgac cttcaagcag gttcattaca
     2641 agtatggcta tggtcgagac gtcttgtcgg atatcaattt aaccgttccc caagggtcta
     2701 aggtggcttt tgtggggatt tcagggtcag gtaagacgac tttggccaag atgatggtta
     2761 atttttacga cccaagtcaa ggggagatta gtctgggtag tgtcaatctc aatcagattg
     2821 ataaaaaagc cctgcgccag tacatcaact atctgcctca acagccctat gtctttaacg
     2881 gaacgatttt ggagaatctt cttttgggag ccaaggaggg gacgacacag gaagatatct
     2941 tacgggcggt cgaattggca gagattcgag aggatatcga gcgcatgcca ctgaattatc
     3001 agacagaatt gacttcggat ggggcaggga tttcaggtgg tcaacgtcag agaatcgctt
     3061 tggcgcgtgc tctcttgaca gatgcgccgg tcttgatttt ggatgaggcg actagcagtt
     3121 tggatatttt gacagagaag cggattgtcg ataatctcat agctttggac aagaccttga
     3181 ttttcattgc tcaccgcttg actattgctg agcggacaga gaaggtagtt gtcttggatc
     3241 agggcaagat tgtcgaagaa ggaaagcatg ctgatttgct tgcacagggt ggcttttacg
     3301 cccatttggt caatagctag aaagaggaga ggatgaaacc agaattttta gaaagtgcgg
     3361 agttttataa tcgtcgttac cataattttt ccagtagtgt gattgtaccc atggcccttc
     3421 tgctcgtgtt tttacttggc tttgcaactg ttgcagagaa ggagatgagt ttgtccacta
     3481 gagctactgt cgaacccagt cgtatccttg caaatatcca gtcaactagc aacaatcgta
     3541 ttcttgtcaa tcatttggaa gaaaataagc tggttaagaa gggggatctt ttggttcaat
     3601 accaagaagg ggcagagggt gtccaagcgg agtcctatgc cagtcagttg gacatgctaa
     3661 aggatcaaaa aaagcaattg gagtatctgc aaaagagcct gcaagaaggg gagaaccact
     3721 ttccagagga ggataagttt ggctaccaag ccacctttcg cgactacatc agtcaagcag
     3781 gcagtcttag ggctagtaca tcgcaacaaa atgagaccat cgcgtcccag aatgcagcag
     3841 ctagccaaac ccaatccgaa atcggcaacc tcatcagtca aacagaggct aaaattcgcg
     3901 attaccagac agctaagtca gctattgaaa caggtgcttc cttggccggt cagaatctag
     3961 cctactctct ttaccagtcc tacaagtctc agggcgagga aaatccccaa actaaggttc
     4021 aggcagttgc acaggttgaa gcacagattt ctcagttaga atctagtctt gctacttacc
     4081 gtgtccagta tgcaggttca ggtacccagc aagcctatgc gtcagggtta agcagtcaat
     4141 tggaatccct taaatcccaa cacttggcaa aggttggtca ggaattgacc cttctagccc
     4201 agaaaatctt ggaggcagag tcaggtaaga aggtacaggg aaatctttta gacaagggga
     4261 aaattacggc gagtgaggat ggggtgcttc atcttaatcc tgagaccagt gattctagca
     4321 tggttgcaga aggtgcccta ctagcccaac tttatccatc tttggaaaga gaagggaaag
     4381 ccaaactcac agcctatcta agttcaaaag atgtagcaag aatcaaggtc ggtgattctg
     4441 ttcgctatac tacgactcat gatgccggga atcaattttt tctagattct actattacaa
     4501 gtattgatgc gacagctact aagactgaga aagggaattt ctttaaaatc gaggcggaga
     4561 ctaatctaac ttcggagcag gctgaaaaac ttaggtacgg ggtggaaggc cgtctacaga
     4621 tgattacggg caagaaaagt tatctacgtt attatttgga tcaatttttg aacaaagagt
     4681 aatgttcgtg tttttagagt taaataattt ttaaactgtg agaaagattc ttcttgcagt
     4741 tttttcttta caatttttga aaaacatatg ctatttattc ggttaaattc ttgtgttttt
     4801 tggttttttg tggtaaaatg tgctcaagta atacgaaagg cgaactttaa aatgtcaaaa
     4861 caattgatct attcgggaaa agctaaagat atctatacaa ctgaggatga aaatcttatt
     4921 atttcaactt acaaggacca ggcgactgct ttcaacggtg tcaagaagga gcagattgta
     4981 ggtaagggag tcttgaataa tcagatctca tcttttattt ttgagaaatt aaatgcggct
     5041 ggtgtggcga ctcactttgt ggagaaactt tcagacacgg aacaactcaa taaaaaggtt
     5101 aagattattc ctttggaagt cgtgctccgc aactatactg ctggttcctt ttcaaaacgt
     5161 tttggtgtgg atgagggaat cgccttggag actccgattg tcgaatttta ctacaaaaat
     5221 gatgatttgg atgatccatt tatcaatgat gagcatgtga aattcctaca gattgcgggt
     5281 gaccagcaga ttgcctactt gaaggaagaa acgcgtcgta tcaatgaact attgaaagtc
     5341 tggtttgctg agattgggct taaattgatt gactttaagc tagagttcgg ttttgacaag
     5401 gatggcaaga ttatcttggc agacgaattt tcaccagata actgccgctt gtgggacgct
     5461 gatggcaacc acatggataa ggatgttttc cgtagaggat tgggagaact aaccgacgtt
     5521 tatgagattg tttgggaaaa gttgcaggaa ttgaaataat ctgtttgcaa cggaaaacct
     5581 tcgtctctca actaaaagga ctcaggctga aaaggtcccc cagacctttt cactctgtag
     5641 agaactaggt gaactaacag atgtttacga aattgtctgg gaaaagttgc agggtttaaa
     5701 ataacaacct caaggctgtt tgggaatatt gcaagagctg aaataaagga ataagaattg
     5761 atggataaac gtatttttgt tgaaaaaaag gctgattttc aggtcaagtc agagagtttg
     5821 gttagagagc tccagcacaa cttgggactg tcaagcttga aaagtattcg tattgtgcaa
     5881 gtatatgatg tatttgactt ggctgaggac ttgtttgcac ctgcagagaa gcacattttc
     5941 tctgagcagg gaaccgacca tgttttagat gaagtatctg tgcaggcgga tcttgctaac
     6001 tatgctttct ttgccattga aagtctgcca gggcagtttg accagcgtgc agcttcgtca
     6061 caggaagcct tgcttttgtt gggaagttcg agtgacgtga cagtcaacac agcccaactt
     6121 tacttggtga ataaagatat tgatgcgact gagttggaag ctgtcaaaaa ctacctgctc
     6181 aatccagttg attctcgttt caaggatatc acgacaggga ttgccaagca ggagttttca
     6241 gagtcagaca agaccattcc aaaattgact ttctttgaaa gctatacagc agaagacttt
     6301 gctcgctaca aggccgagca agggatggcc atggaagtgg atgatttgct ctttatccaa
     6361 gactacttta agtcaatcgg gcgcgtgcca actgagactg aactcaaggt tttggacact
     6421 tactggtctg accactgccg tcatacgact tttgagacag agttgaaaca catcgacttt
     6481 tcagcttcta aatttcaaaa gcaattgcag tcaacctatg acaagtatat tgccatgcgc
     6541 gaggagttag gtcggtctga aaaaccacaa accttgatgg atatggcgac tattttcggt
     6601 cgttatgagc gtgctaatgg acgattggat gatatggaag tctctgacga aatcaatgcc
     6661 tgctcagttg aaattgaagt ggatgttgat ggtgtcaagg aaccttggct cctcatgttt
     6721 aaaaatgaaa cccacaacca tccaacagaa attgagccat ttggtggagc ggctacctgt
     6781 atcggtggag ctattcgtga tccgttgtca ggccgttcct atgtttacca agccatgcgt
     6841 atttcaggtg ctggtgatat tacagcaccg atttcggaaa ctcgtgctgg gaaattgcca
     6901 caacaagtca tttctaaaac agcagctcat ggttattctt catatggtaa ccagattggg
     6961 cttgccacaa cctacgttcg tgaatacttc cacccaggct ttgtagctaa acgtatggaa
     7021 cttggtgccg ttgttggtgc ggctcccaag ggcaatgttg tccgtgaaaa acctgaagca
     7081 ggtgatgtga tcatccttct cggaggcaaa acaggtcgtg atggtgtcgg tggtgcgacg
     7141 ggctcttcta aggttcaaac agttgagtct gtagagactg ctggtgctga ggttcaaaaa
     7201 ggaaatgcca tcgaagaacg caagattcag cgcctcttcc gtaatggcaa tgtcactcgt
     7261 ctgatcaaga agtccaatga ctttggggca ggcggcgtct gtgtggctat cggtgaattg
     7321 gcagacggtc ttgaaatcga cctcaacaag gtgcctctta aataccaggg cttgaatggt
     7381 acagaaattg ccatctctga atcacaagaa cggatggcgg tcgtggttcg tcctgaagat
     7441 gtggatacct tcgttgccga atgtaacaaa gaaaatattg atgctgttgt ggtggcgaca
     7501 gtaactgaaa aaccaaatct tgtcatgcac tggaatggtg agacaatcgt tgacttggag
     7561 cgtcgtttcc ttgacaccaa tggtgtgcgc gtggttgtcg atgccaaagt tgtggacaag
     7621 gatgtcaaac tcccagaaga gcgtcaaaca tctgctgaaa cactggaatc agataccctt
     7681 acggttctat ctgacctcaa ccatgcaagt caaaaaggat tacagactat ctttgactgc
     7741 tctgttggac gctcaacggt taatcaccca cttggtggtc gttaccaact cacaccaact
     7801 gaggcatctg tgcagaaatt gccagttcaa cacggtgtga ctcatactgc gtcggtcatt
     7861 gctcaaggtt tcaacccata tgtagctgaa tggtctccat accacggtgc tgcttatgcg
     7921 gttatcgaag caactgctcg tttggtggct gctggtgcca actggtccaa ggctcgtttc
     7981 tcttaccaag agtatttcga gcgtatggat aaacaagcag agcgtttcgg tcagccagta
     8041 gctgctcttc taggttctat tgaagcacaa attcagcttg gcttgccatc tatcggtggt
     8101 aaggactcca tgtctggtac ctttgaagaa ttgaccgttc cgccaacctt ggttgccttt
     8161 ggggtgacga cggcagatag ccgtaaggtg ctctctccag aatttaaagc tgttggggaa
     8221 aatatctact acatcccagg tcaagccctc tctgcagaga ttgattttga cttgattaag
     8281 aaaaatttta ctcagtttga agccatccaa gctgaccata aagtgacatc tgcatcagct
     8341 gtcaaatacg gtggtgtagt tgaaagtttg gctcttgcta cctttggaaa ctatattggt
     8401 gcagaggtga ccttgcctga acttaaaaca gctttgacag ctcaattagg cggctttgtc
     8461 ttcacatctc ctgaagaaat tgctggagta gagaaggttg gacaaacgaa agcagacttt
     8521 acactgactg tcaacggtgt gaagctagat ggacacaagc ttgacagtgc atttcaaggg
     8581 acattggaag aagtttaccc aacagaattt acccaagcga aagaactaga agaagtacca
     8641 gctgtggcat cagatgttgt gattaaagcc aaagaaaagg ttgaaaaacc tgtggtttac
     8701 atcccagtct ttccaggaac caactcagaa tatgattcag ctaaggcctt cgaaaaagaa
     8761 ggtgcagagg tcaatttggt gccattcgtg accttgaatg aagaagctat tgtcaagtca
     8821 gttgaaacta tggttgacaa tatcgacaag actaatattc tcttctttgc tggtggattc
     8881 tcggctgcgg atgaaccaga tggttcagct aagtttatcg tcaatatcct gcttaatgaa
     8941 aaagtgtgtg tggctattga tagctttatc gcccgtggtg gtttgattat cggtatttgt
     9001 aatggattcc aagccttagt caaatcgggt ctcctaccct acggaaactt tgaagctgct
     9061 aacagtacta gcccaaccct cttctacaat gatgccaacc aacacgtggc caagatggtg
     9121 gaaactcgca ttgccaatac caactcacca tggttggctg gtgtgcaagt gggcgatatc
     9181 cacgctattc ctgtttcgca cggtgaaggg aagtttgtcg tgacggctga ggaatttgca
     9241 gagctccgtg acaatggaca aattttcagc caatacgttg actttaacgg taaaccaagt
     9301 atggattcta agtacaatcc gaatggttct gtccatgcca tcgaaggaat taccagcaag
     9361 aatggtcaaa tcatcggtaa gatgggccac tcagaacgtt atgaggatgg tcttttccaa
     9421 aatatcccag gcaataaaga ccaacacctg ttcgcatcag cggttaaaca tttcactgga
     9481 aaataagact tacagatttt ctaatagata gtatcagtaa tgtaaaagtc atgtaaatct
     9541 agctcttgat gattacaaat gaaaattagg tataaaaaat gacatacgaa gtaaaatctc
     9601 ttaatgaaga atgtggtgtt ttcggtattt ggggacatcc agatgctgct aagttgacct
     9661 attttggact ccacagtctt caacaccgtg gtcaggaggg ggcaggaatc ctctccaatg
     9721 atcaaggaca actgaagcgc catcgtgaca tggggctttt atcagaagtt ttcagaaatc
     9781 cagccaattt ggataaattg acaggagctg gtgcgattgg gcatgtgcgt tatgcgactg
     9841 ctggcgaagc ttctgttgat aacatccaac ccttcctctt ccgttttcac gatatgcagt
     9901 ttggtttggc tcataatgga aatctgacca atgcagcctc tctcaagaaa gaactggaac
     9961 aaagaggagc aattttcagc gcgacttcgg actctgaaat cttggctcac ctcattcgtc
    10021 gcagtcataa tcctagcctg atgggcaaaa tcaaggaagc gctcagcctt gtcaaaggtg
    10081 gttttgccta tatcttgctg tttgaggaca agttgattgc ggctcttgac cctaatggct
    10141 ttcgtccgct ttctatcggg aaaatggcca acggagcggt ggttgtttcc tctgaaacct
    10201 gtgcttttga ggtcattggt gccgagtgga ttcgtgattt gaagccaggt gagattgtga
    10261 tcattgatga cgagggcatt cagtatgaca gctatacaga tgatacccag ttggcgattt
    10321 gttctatgga gtatatctac tttgcccgcc ctgattctaa tatccacggt gtcaatgtcc
    10381 atacggcacg taagagaatg ggagcgcaat tggcgcgaga atttaagcat gaggcagata
    10441 ttgtagttgg tgtgcccaat tcttccctaa gcgcggctat gggatttgcg gaagaatcag
    10501 gcttaccaaa tgaaatgggt ctgatcaaaa accaatacac ccagcgaact tttatccaac
    10561 cgactcaaga attgcgggag caaggagtgc ggatgaaact gtctgctgtt tcgggtgttg
    10621 tcaaaggcaa acgtgtggtt atggtggatg attccattgt acgtggaaca acctctcgtc
    10681 gtatcgttca gctcttgaaa gaagcgggtg cgactgaggt tcacgttgcc attggaagtc
    10741 ctgcactagc gtatccatgt ttctacggga ttgatatcca gacccgtcag gagctgattg
    10801 cagccaatca tacggtcgaa gaaactcgcc aaatcattgg tgcggacagt ctgacttatc
    10861 tttcaattga tagcttgatt gagtcgattg gtatcgaaac agatgcgccg aacggtggtc
    10921 tctgtgtcgc ttactttgac ggtgactacc caacgcctct ctatgactac gaagaagact
    10981 atcgtagaag tttggaagaa aagaccagtt tttacaagta ggcgacagat tctccattaa
    11041 agaaaaggaa aaaacaaatg acaaataaaa atgcatatgc ccagtcgggt gtggatgttg
    11101 aagcgggtta tgaagttgtt gaacggatta aaaagcacgt ggcccgtacg gagcgtgcag
    11161 gtgtcatggg agctcttggt ggctttggtg gtatgtttga cctttccaag actggggtta
    11221 aagaacccgt cttgatttca gggactgacg gtgtcggaac caagctcatg ttggctatca
    11281 agtacgacaa gcacgatacc atcgggcagg actgtgtggc catgtgtgtc aacgacatca
    11341 ttgctgcagg tgcggaaccc ctctattttc tcgactacgt agcgacaggg aagaatgaac
    11401 cagctaagct agaacaagtg gttgctggtg tggcagaagg ttgtgtgcag gctggtgctg
    11461 ccctcatcgg tggggaaacg gctgaaatgc cgggcatgta cggcgaagac gactatgact
    11521 tggctggttt tgcggtcggt gtggctgaaa aatctcaaat cattgacggt tcaaaggtgg
    11581 tagagggaga tgttcttctc ggacttgctt caagtgggat tcactcaaat ggttactctt
    11641 tggttcgtcg tgtctttgcg gattacacag gtgaggaagt cctaccagaa ttggaaggca
    11701 agaaacttaa ggaagttcta cttgagccga ctcgtatcta tgtcaaggct gtcttgccgc
    11761 tcatcaaaga agagttggtc aacggcattg cccacatcac aggtggtggc tttatcgaaa
    11821 atgtccctcg tatgtttgca gatgacctag ctgctgaaat tgatgaaagc aaagttccag
    11881 tgcttccaat tttcaaagcc cttgaaaaat atggtcagat taaacacgaa gaaatgtttg
    11941 aaatcttcaa tatgggtgtg ggacttatgt tggcggtcag ccctgaaaat gtagagcgtg
    12001 taaaagaatt gttggatgaa gcagtctatg aaattggtcg catcgtcaag aaagaaaacg
    12061 aaagtgtcat tatcaaatga aaaaaatagc ggtttttgcc tctggtaatg gctcaaattt
    12121 tcaggtgatt gccgaagaat ttccagtgga gtttgtcttt tcagaccatc gtgatgccta
    12181 tgtgcttgag cgtgcaaagc agctcggcgt tctgtcctat gcttttgaac tcaaggagtt
    12241 tgagagcaag gcagactacg aagcagccct tgtcgaactc ttggaagaac accagattga
    12301 cttggtttgc ctagcaggct acatgaaaat cgttggacca accttattgt cggcttatga
    12361 aggtcggatt gtcaacattc atccagccta cttgccagaa tttccaggag ctcatgggat
    12421 tgaggatgct tggaatgctg gcgtgggtca gtctggtgtg accattcact gggtggattc
    12481 gggtgtggat acaggccagg tcatcaaaca ggttcgtgtg ccacgactag ctgatgatac
    12541 cattgacaga tttgaagctc gcatccatga agcagagtac aggctgtatc cggaagtagt
    12601 gaaggctcta tttacagatt gactttttga tgattcatat gatatctttg attttaaatt
    12661 ggagtcagtg tttgttgaag acggcttcaa acggaggtat ttgtaatatt agaatctaaa
    12721 aaaacaactc gatatgtatt ttatgtctat ctgatgttat taacttgggg aatcttattt
    12781 aagtttgaaa caaatcctga atttatagca tttttcttag ctccaaggta tatcaattgg
    12841 attccatttt cagaaccact aatagtcgat ggaaaaattg tttttgctga aatgttattt
    12901 aatctgattt cctttattcc attaggtgtt tgtttccctt tgataaaaac taatttatct
    12961 agtttaagaa tagtcgggac aggtttcttg attagtttat tgtttgagtg cttacagtat
    13021 attttagcaa taggtataac agatataacg gatttgactt taaatacgct aggtgtctgt
    13081 gtaggcttac tgatttatca aatttttata agagtgttca aatcacagac tagaaaatgg
    13141 atcaatatct taggtatgct tagccttggt tttgcttatc ttgttttact gttactgcat
    13201 ttaattggtg tttaactaat gattaaaaag gagaatataa tgactaaacg cgtcttaatc
    13261 agcgtctcag acaaagcggg cattgttgaa tttgcccaag aactcaaaaa acttggttgg
    13321 gagattatct cgacaggtgg aactaaggtt gcccttgata atgctggggt ggataccatt
    13381 gctatcgatg atgtgactgg tttcccagaa atgatggacg gtcgtgtgaa gaccctccac
    13441 ccaaatatcc acggggggct tctcgctcgt cgtgacttgg atagccactt ggaagcggct
    13501 aaggacaaca agattgagct cattgacctt gtggtggtca acctttaccc atttaaggaa
    13561 actatcctta aaccagatgc gacttatgct gatgcagttg aaaatatcga tattggtggg
    13621 ccatctatgc ttcgttcagc agcgaaaaat catgccagtg ttacagttgt ggtagatcct
    13681 gctgactacg ctgtggtttt ggacgaattg gcagcaaacg gcgaaacctc ttatgaaact
    13741 cgccaacgtt tagcagccaa agtatttcgt cacacagcgg cttatgacgc cttgattgca
    13801 gaatacttca cagctcaagt gggtgaaagc aagcctgaaa aactcacttt gacttatgac
    13861 ctcaagcaac caatgcgtta cggtgagaat cctcaacaag acgcggactt ttaccagaaa
    13921 gctttgccta cagactactc cattgcttca gccaaacagc tcaacgggaa agaattgtca
    13981 tttaataata tccgtgatgc agatgctgct atccgtatca tccgtgactt caaagatagt
    14041 ccaaccgttg tggctctcaa acacatgaat ccatgtggaa ttggtcaagc tgatgacatc
    14101 gagactgctt gggactacgc ttatgagtct gacccagtgt ctatctttgg tgggattgtc
    14161 gtcctcaacc gtgaggtgga tgctgcgaca gctgagaaga tgcacggcgt tttcctcgaa
    14221 atcatcattg caccaagcta tacggatgaa gcgctagcca ttttgatcaa taaaaagaaa
    14281 aacttgcgta tccttgcctt gccatttaat gctcaagagg ctagcgaagt ggaagcagaa
    14341 tacacaggtg tagtcggtgg acttctcgtg caaaatcaag acgtggtcaa ggaaagccca
    14401 gctgactggc aagtggtgac caaacgtcag ccaaccgaga cagaagcgac tgctcttgag
    14461 ttcgcttgga aggctatcaa gtacgtcaaa tcaaatggta ttatcgtgac caacgaccac
    14521 atgacacttg gtgttggtcc aggtcaaacc aaccgtgtgg cttctgttcg ccttgccatt
    14581 gaccaagcca aagatcgtct ggacggggcg gtccttgctt cagatgcctt cttcccattt
    14641 gcggataacg tggaagaaat cgctaaagca ggaattaagg ccatcatcca gcccggtggc
    14701 tctgtccgtg accaagaatc catcgaagca gcggataaat acggcttgac tatggtcttt
    14761 acaggtgtga gacattttag acattaagaa gataaaaggg aagaaaacag tttctttcct
    14821 tttttggctt aaaatgctaa ctgaaacaag attaaaacga acttttttga tataatattg
    14881 gtaaataatt cgcaaaagag gttgaggaat gaaactgctt gttgtcggtt cgggtggtcg
    14941 tgagcatgcg attgctaaaa agttacttga atcaaaagat gtggaaaaag tctttgtagc
    15001 tcctgggaat gatgggatga ctctggatgg tttggaattg gtaaatatct ctatttccga
    15061 acattctaaa ttgattgact tcgcaaagac caatgatgtt gcttggacct ttatcggtcc
    15121 agatgatgcc cttgctgctg gtatcgtgga tgattttaac caagctgggc ttaagacctt
    15181 tggtccgact agggctgcag cggagctgga gtggtccaag gattttgcca aggaaatcat
    15241 ggtcaaatat ggtgtttcga cagcagccta tggcacattt tcagatttcg aggaagcaaa
    15301 ggcttatatc gaaaagcatg gtgcgcctat cgtagtcaag gcggatggct tggcgcttgg
    15361 gaagggtgtc gtcgttgctg agacggttga gcaagcggtc gaagccgctc atgagatgct
    15421 tttggacaat aaatttggtg actcaggtgc gcgcgtggtt attgaggaat tccttgaagg
    15481 agaggaattt tcactctttg cctttgtcaa tggtgataag ttctacatca tgccaacggc
    15541 tcaggaccac aaacgtgcct acgatggcga caaagggcct aacacgggtg gtatgggtgc
    15601 ctatgcgcca gttccacact taccacagag tgtagttgat acagcggttg acaccattgt
    15661 caagccagtt ctagaaggga tgattaaaga aggtcgccct tatctgggag ttctttacgc
    15721 agggcttatc ctgacagctg atggaccgaa agtcatcgag ttcaacgctc ggttcggaga
    15781 tccagaaact cagattatct tgcctcgctt aacctctgac tttgctcaaa atatcacaga
    15841 tatcctggat agcaaggagc caaatatcat gtggacggac aagggtgtga ctctgggtgt
    15901 ggttgtcgca tccaagggct acccgctaga ctatgaaagg ggcgttgagt tgccagccaa
    15961 gacagaaggc gatgtcatca cctactatgc aggggctaag tttgcggaaa atagcagagc
    16021 actgctctca aacggcggac gagtttatat gctcgttacc acagcagata ccgtcaaaga
    16081 agcccaagcc agcatctacc aagaactatc ccaacaaaaa atagaaggac tcttctaccg
    16141 aacagatatc ggaagcaagg caattaagta aagatataag aataacgcgc cgtagtcgcc
    16201 aaacacgata atggtcgtcg tggtgaaaag accagaacag tgaatgttct ggtcaggggg
    16261 aaatttggag accgtaggct caaagtttag gaatgaaacc gaaggtttgc ttccgcctcc
    16321 atcacctaag atcattatta aaaaagaaga aaaggaaaat tatgaccaaa ccaattattt
    16381 ccatcatcat gggctcaaaa tccgattggg caaccatgca aaaaacagca gaagtcttag
    16441 accgcttcgg tgtagcctac gaaaagaaag ttgtttctgc ccaccgtaca cctgatctca
    16501 tgttcaaaca tgcagaagaa gcatatagcc gtggtattaa ggtcatcatc gcaggtgctg
    16561 gaggcgcagc ccacttgcca ggaatggtag ctgccaaaac aacccttcct gtcatagggg
    16621 tacctgtcaa gtctcgtgct cttagtggag tggattcact ctattctatc gttcagatgc
    16681 cgggtggggt gcctgttgcg accatggcta tcggtgaagc tggagcgact aacgcagctc
    16741 tctttgccct ccgtctcctc tctgtagaag ataagtccat tgcggatgca cttgccaact
    16801 ttgctgaaga acaaggaaaa atcgcagagg agtcgtcaaa tgagctcatc taaaacaatc
    16861 ggaattatcg gtggcggtca actgggtcag atgatggcca tttctgctat ctacatgggc
    16921 cacaaggtta tcgcgctgga tcctgcggcg gattgcccgg tctctcgtgt ggcggaaatc
    16981 attgtggcac cttataacga tgtagacgcc ctccgtcagt tggcagaccg ttgcgatgtc
    17041 ctcacttacg agtttgaaaa tgtcgacgct gacggtttgg atgccgttat caaggatgga
    17101 caactccctc aagggacaga cctgctccgc atttcgcaaa atcgtatttt tgaaaaggac
    17161 tttttgtcaa acaaggctca agtcactgtg gcaccctaca aggtcgtgac ttctagccta
    17221 gacttggcag atatcgactt gtcgaaaaac tatgtcctca agactgcgac tggtggctac
    17281 gatggtcatg gacaaaaggt tattcgttca gaagtagact tggaagcagc ctatgcgcta
    17341 gcagaatcag cagactgcgt cttggaagaa tttgtcaact ttgcccttga gatttctgtc
    17401 atcgtgtcag gaaatggcaa ggaggtgacg tttttcccag ttcaggaaaa tatccaccgc
    17461 aacaatatcc tgtctaagac catcgtacca gcccgcattt ctgaaagtct agtagacaag
    17521 gctaaagcta tggcagtgcg aatcgcagaa caactcaact tgtctggaac tctctgtgtg
    17581 gaaatgtttg cgactgatga tgacgttatt gtcaatgaaa tcgccccacg accacataac
    17641 tctgggcact attctattga agcctgtgat ttctctcagt ttgacaccca tattctcggt
    17701 gttctcggag caccattacc agtcatcaaa ctccatgcgc cagccgttat gctcaatgtc
    17761 ctaggtcaac acgtcgaggc tgctgaaaag tatgtcgcag aaaatccaag cgcccacctc
    17821 cacatgtatg gtaaaataga agcaaagcat aatcgtaaga tgggacatgt gaccttgttt
    17881 agtgatgtac cggatagtgt ggatgagctt ggggaaggga ttgattttta ggacaagtct
    17941 atgatacaaa ttatcgttaa tacatttatt gaaaaggata agactggagc agttgttgaa
    18001 gtgttgtatg ccagtgctga ccaagataag gtacaagcta aatatgaaga actagctgca
    18061 caataccccg aaaattattt agctatctat gatgtaccgc tggatacgga tttgaataca
    18121 ctagatcatt acccgtctgt gtttattgga aaagaggagt ttgagtagaa atcttggttt
    18181 acctagatag cttattccca acagcttaag aagaaaggaa aaattaacac atgatcaacc
    18241 gttactctcg ccctgagatg gcgaatattt ggagtgaaga aaataaatac cgtgcttggc
    18301 ttgaggtgga aatcctctct gacgaggcat gggctgagtt gggggaaatc cctaaggaag
    18361 atgtggcttt gattcgcaag aaggcggact ttgacatcga ccgtattttg gaaattgagc
    18421 aggagacgcg ccacgatgtg gtggctttca cgcgtgcggt ttctgagact cttggtgaag
    18481 agcgcaagtg ggttcactat gggttaactt ctaccgacgt ggtggatact gcttatggtt
    18541 acctctacaa gcaggccaac gacatcatcc gtcgtgacct tgaaaacttc actaatatca
    18601 tcgctgacaa ggccaaggag cacaagttca ccatcatgat ggggcgtact catggtgtgc
    18661 acgctgagcc gacaaccttt ggtcttaaat tggcaacttg gtacagcgaa atgaaacgca
    18721 atatcgagcg cttcgagcat gcggctgctg gtgtagaagc tggtaagatt tctggtgcgg
    18781 ttgggaactt tgccaatatc ccaccatttg tagaggagta tgtctgcgat aaacttggca
    18841 tccgtgccca agaaatctct acacaagtcc ttcctcgtga ccttcacgct gagtactttg
    18901 cggttcttgc cagcattgcg acttcaatcg aacgtatggc gactgagatt cgtggtctac
    18961 aaaaatctga gcaacgcgaa gtagaagagt tctttgctaa agggcaaaaa gggtcttcag
    19021 caatgcctca caaacgcaac ccaatcggtt ctgaaaatat gactggtctg gcgcgtgtca
    19081 ttcgtggtca catgattacg gcttatgaaa acgtcgctct ctggcacgaa cgcgatattt
    19141 ctcactcatc agctgagcgt atcatcacac cagatacgac cattttgatt gactacatgc
    19201 tcaaccgttt tggaaatatc gtcaagaact tgacagtctt cccagaaaat atgatccgaa
    19261 acatgaactc gacttttggt cttatcttta gccaacgggc tatgttgaca ttgattgaaa
    19321 aaggcatgac ccgtgagcaa gcctatgact tggtgcaacc aaaaacagcc tactcttggg
    19381 acaaccaagt agactttaaa ccacttcttg aggcagattc agaagtaaca tcacgtctca
    19441 cacaagaaga aatcgatgaa atcttcaacc cagtttatta caccaaacga gtggatgata
    19501 tctttgaacg tcttggacta ggtgattaat taaaaaataa acagcgagct tcaatctcgc
    19561 tgtttatttt ttatcgaaaa gacttagtct tcttttcttt tagtgagtcc ataggctgct
    19621 agtgtggaca tgagtcctgc gactactagt cctgcagaat cgtgagttcc tgtttcagga
    19681 agttttttct ctgttaccac aggagctgga tcttgaggaa gaactttgct ttcctcagca
    19741 ggagcagttg atggagctgg ttggcttggg atttctagtt ttggtttttc ttcagcaata
    19801 gcggcttgtc cgttttcatc gcctacatgt gttaccatag ttccgacttc gactatttga
    19861 gtaacggctt cctgtgctac gacactattt acaagtgttt tcacttcctt accatcggca
    19921 gaagtgctca cagagtagaa gttgctacga tgtccattga cgcccttagt aatgacttgt
    19981 gtttttcctt tgagtaagag tggattttca cgagtcactg tggtaaatgg aatgtcttct
    20041 tcttggatat ccagtctagg ttttacctca gtagttggtg caagaccact ttcatcaccc
    20101 ttgtgagtta caggagcgcc aacttcaacc acttggttta taacttcttt ggttacctgg
    20161 ctatcaagga ctgtttctgt tgtttttcca ttttcagtga gtacagagat gtaatgagtt
    20221 cgttcacctt tgactcctgc tgtgataata ttttcctgac cggctgggag gttaggattt
    20281 tctttcttga taacttcaaa tggaatttct tcagttcttg tgatgagttc tggtctggtt
    20341 tcaacattgg cagccacttc attttcatct aggcttcctg aatgagttac agctggtttg
    20401 aggccttgaa gagcggcttt taggttggct acaagtgtgt caagctcagc ttgtttatta
    20461 cggttgaggt tgtaatttag agctgtttta gctgcgtcaa gggcctcaag actttcttta
    20521 ctatatcctt ctaagtttgt aggaatttta gctaattctt cgcggagagc attataatta
    20581 gcacggaagt agtctttgtt gtggtctgca aaggcagtca tgagttcaaa gatttcctct
    20641 tccttgtatt cagcgcttgg tctatctgcc cagattgaaa gcatacttcc gactgttgga
    20701 agatctactt caggatattt ggtagaagct agttgattga atggtgtttt tccagtattc
    20761 tcaatagctt tcttgaggaa accaccacca tcttctggtt tttgaccaag aatgtagtac
    20821 cagtcaccgt tggtattcaa gaatttatag cctttgcttg ctaggtattg aggtgatgcg
    20881 aggttatatc cccaccagcc tttagaccag taagaaatca agacatcttt gtcaaactga
    20941 acatcgtcct tgtcttcata gtagaagcca tcgttgaagg ccattggttg aagccctctt
    21001 tctttggcca tagctgcgag ggtgttggca tattcggcaa atttgccata gagttgatac
    21061 cacttgaggt agtaccagcc ttgggcacta gtcgcatcgt tggcgtattc gtcagtacca
    21121 aagttgaaaa tctttgtttt acctgcaaag aagtccatgt atttaccgat gagggctttt
    21181 acaaagttca tcgcttcttc gtttttcaag tccatagttg tttttgaaac tttatcaaag
    21241 tgggcttgag gatttttaat acctaatttt tccatggcaa ccagcatagc atccatgtga
    21301 cctggactgt taatagctgg gatgagaccg atgtccttag atttagcgta ttcaattagc
    21361 tctgtcactt ctgcctgtgt tagtgcagta ccgtttggat cgtcgtagta agctttagtt
    21421 ccttcgataa tagctttttt aacgtcatca ctagcatagg tttttccgtt ggcagtaatg
    21481 gtcatatcat cgagtagaaa gcgaagtccg tcatttccta gaaggagatg gacatcagaa
    21541 tatccgagct cactggcctt gtctacgatg cgtttgagct ggttcagagt aaagtatttg
    21601 cgtccagcat cgattgagat tatcttgttt ttggcaagtt tttcaacctc acgtttagct
    21661 tcttcttctt tttgagcttc aggcgtgagg gtcaagttgt tgacagtttc ttgaagttta
    21721 gcaatggctt gatcaatcgt atcttgttgg gcacggctaa ggttgctatc gagagagcga
    21781 atagcttttt cagcttcttt tacggccgtg acgctttctg cagtataacg gttcaggtct
    21841 tttggtacct cgttaagtgc ttgctctgca gattcataat cagctgcgaa gtattcagcg
    21901 ttggcatttg caaaatgacg catgagtttg aagaggcgtg atggtgaata acgtgcagat
    21961 ggagtgtcag cccaagcagc taccatacca ccgatgattg ggatatcagc tccttctgtt
    22021 tttggtacag aagtgattgg tgtgttttta ataccattga gcccctgatc gagattgtac
    22081 cagccttggc catcagcgtt tcgtccaaga acgtagtacc aagcatcatt ggtattaagg
    22141 atttggtgac ctttttcagc tagtagttta gaagaagcga catcgtagcc tccccaacca
    22201 ccagtccaca tagaaacgat gatgtctttg tcaaaactac caaagcttgt gtcgctattg
    22261 tagtagatac cgtcgttaaa ggccattggt ttgagaccgt gcgattttac aatacgagcg
    22321 aggtcattgg cgtaggcaat aaatttttca tagcctttta cagggtagcc ttcgtttgga
    22381 tagtatttat cagcttgaag cacactccaa cctttagcat ctgtcgcatc attggcatat
    22441 tcatcaagtc cgatgttgaa gatttcagtc tttttcgcga aataagcagc atacttgtcg
    22501 ataagggctt ttgtaaaagc gacagcttgt tcgttgtcaa gatcgacagt acgggctgat
    22561 tccttcccaa aatagctaaa gttagggttt tggattccca attctttcat ggcattgaga
    22621 atcgcatcca tgtgcccagg actatttact gtcggaatga gaccgatacc tttatctttg
    22681 gcatagttaa tcagatctgt catttgactt tctgttaagt gattgccgtt tggatcgtcg
    22741 taataatcat ttgtaccttt ttcaatggcg cgtttgacat cgtcactggc ataggtcttg
    22801 ccgttagctg tgatgctcat atcgtccaac atgaaacgga gtccatcatt tccgactaat
    22861 aggtgtaaat cagtgtagcc ataatgtttc gctttatcga tgatttcctt gagctgttct
    22921 ggtgagaaat atttacgtcc agcatcaata gaaacaattt tctttttcgc tagtttttca
    22981 tttacagttg cagcacgttc ctttcctgcc tctgtttccg gtttgtcagc ctctgctttc
    23041 gcttcatctt ttttagctgg tttatccttg tcagtcttgt ctgtatttga ctctttagaa
    23101 tcaacctctt tcgcttcttc ctttttaggg ctagcttctt ctgccttttt attagcagtt
    23161 tctttttcag cagaagttgg agttaccacg tctgctttat cactaggagt tgaactaact
    23221 tcctcttgtg gtttttcttc tgtttttgga agactagcta ccttatcagt agctggagtt
    23281 tctgtttcta cagtttttgg agcttctggt tgaagctctg ctttaggtgt ttcctcagtc
    23341 cgattttcgg atgattgagg ggaatcagaa accgtatgga tggtcggttg gttttctgta
    23401 gtagtaggag taactccatc ggctgcaaca gtctgtgctt ggaaggcaaa tccaattaga
    23461 acagaagctg ctcctacagc gtatttacga atagaaaaac gctgttgttt ttcatgtttc
    23521 attgcaaaac ctcctgattg cattgttata ttgatagcga ttatataaat caacgccttt
    23581 attttatttc ttatattaac gagagtcaag aggagatgac aaaaaactat aataagtata
    23641 aaaaaatata aaatttaaac ttaagatttc agattggtcg aaaatacata tatatatcta
    23701 gtataatttt tggttctatt tctataaaat attccacaaa ttatagaatc ttccaaaaat
    23761 aggtaagcgc tacctttttg gtgtggtata ataagcatag aaaaagcccg agcgattagg
    23821 ctcaggcttt cttcttagtg atcacggtca catgagatga attcaatctt gtagtaatca
    23881 gatcgtttgt aagtttcact gtattctaaa acttggccag ttgattcgag tttggtgatt
    23941 ttagtttgta ggacagtagg gaattgttca tcgactccga ggactgaagc cgcatgttct
    24001 ggagttggaa agactatttc gttgatttct tcaaagtgtt catcattcat gtgaatgtgg
    24061 tagtctaact tgaaacgatt atagatagaa ctatagtatt caaggtttgg ataatttgcg
    24121 ttgatatatt gttctgggat gtaggatgta tggtagatat aaacgacacc gtttgattcg
    24181 cggatacgtt caatcttgta gtagaattga tcgccgcgta gacccaattt ttccaagtaa
    24241 acaagcttgt ttccgcgttc aattgaaaga acagttacct tatcatcttt agcattgaag
    24301 agttcaatat ctgaaaactc tacaagcttg tgtttgcgtg cacgtgaaac gaaggttcct
    24361 tttccttgtt ggcggacaat atagccatct ttggcaaggt cgtttaaggc gcgaacaact
    24421 gtgatagagc tgacatcgta cattgaaatg agttctgctt cagtgtaaaa tttatctcca
    24481 ctgctaaact gcccagagat gattttattt tttaattcgt cttttatgta ttgatatttg
    24541 ggaattgcca tatttttacc tctattttcc ttctccatag aaaattttac cataaaagcg
    24601 aaaaaaatag tagtcttttg aataaaaaat tagaataata gtttgaaaaa ttaagcgata
    24661 tagggattgc tcatatttta tcaatgtatt ctatacaaaa ttattttagg tcctatattc
    24721 cgaatttaaa gagcgtttga aatgggtcta aaaatgtttg aaactaattg aatgtgtgta
    24781 taatagtaaa aatgcagtaa atatcccgac aatttctatt gacaattcaa acagattggt
    24841 ttataattaa tataacaaca aatgaaagcg caaactttcg cggtcggaag gtagttttat
    24901 gacacgattt gagatacgag atgatttcta tctcgatgga aaatcattta agattttatc
    24961 tggtgccatt cattatttta gggttcctcc agaggattgg tatcattcgc tctataactt
    25021 gaaggctctt ggttttaata cggtagagac ttatattgct tggaatttac acgagcctcg
    25081 tgaaggtgag tttcattttg acggtgatct ggatttagag aaatttctcc aaatagcgca
    25141 ggatttgggt ctctacgcaa ttgtgcgtcc gtctccattt atctgtgcgg aatgggaatt
    25201 cggtggctta ccagcttggc tcttgaccaa gaacatgcga attcgctcat ccgacccagc
    25261 atatatcgag gcagttggtc gctactatga tcagttattg ccaagactgg tgcctcgttt
    25321 gttggacaat ggtggcaata ttctcatgat gcaggttgaa aatgagtatg gttcttacgg
    25381 agaagataag gcttacctga gagcgattcg acagctaatg gaagagcgtg gcgtaacctg
    25441 tcctctcttt acatcagatg gtccatggcg agctactctg aaagctggaa ccttaattga
    25501 agaggacctc tttgtaacag gaaactttgg ttctaaggca ccttacaact tttcgcagat
    25561 gcaggaattc tttgatgaac atggtaagaa atggccactc atgtgtatgg agttctggga
    25621 tggttggttt aatcgctgga aagaaccgat tatcacacgg gatcctaagg aattggcaga
    25681 tgcagttcga gaggttttgg aacaaggctc tatcaatctt tacatgttcc acggtggtac
    25741 aaactttggt ttcatgaatg gttgctcggc tcgaggaact ttggacctgc cacaagttac
    25801 gtcttatgat tacgatgccc ttctggatga agaaggaaat ccaactgcta aatatcttgc
    25861 agtcaagaag atgatggcaa cacatttttc agagtatccg cagttggaac cactctacaa
    25921 agagagtatg gagttggatg ctattccact agttgaaaaa gtttctttgt ttgaaacctt
    25981 agatagcttg tcaagtcctg tagaaagtct ctatcctcaa aagatggagg agctgggaca
    26041 aagttatggc tacctacttt atcgaacaga aacaaactgg gatgcagaag aagaaagact
    26101 tcgtatcatt gatggtcgag atagggccca gctgtatgtc gatggtcagt gggttaaaac
    26161 tcaatatcag acagagattg gggaagatat tttttatcaa ggtaaaaaga aagggctatc
    26221 taggttagat atcttgatag aaaatatggg gcgtgtcaac tatgggcata agttcttagc
    26281 ggatacgcaa cgtaagggaa ttcggacagg ggtctgtaag gatctgcatt tcttactaaa
    26341 ctggaaacac tatccacttc cactagacaa tcctgagaaa attgattttt caaaaggatg
    26401 gactcaagga caaccagcct tttacgctta tgactttaca gtcgaagagc caaaagatac
    26461 ttacctagac ttgtctgagt ttggtaaggg agttgccttt gtcaatgggc agaatctagg
    26521 acgtttttgg aacgttggcc caactctctc actttatatc cctcatagct atctcaagga
    26581 aggtgccaac cgcatcatta tctttgaaac agaaggtcaa tataaagaag agattcattt
    26641 aactcgtaaa cctacactaa aacatataaa gggggaaaac ttatgacaat tgtaggatgc
    26701 cgtattgatg gacgtttgat ccacggacaa gtagccaatc tttgggctgg aaaactaaat
    26761 gtttcacgca ttatggttgt agacgacgaa gttgtcaaca acgatattga aaagagtggt
    26821 ttgaaacttg cgacaccacc aggtgtgaaa ttgagtattt tgccagttga gaaagctgca
    26881 gccaatattc ttgctggtaa atacgatagc caacgtctct ttatcgtggc tcgtaaacca
    26941 gaccgcttcc ttggcttggt agaagcaggt gtaccacttg aaacccttaa tgttgggaat
    27001 atgtctcaaa caccagaaac tcgttctatt acacgttcta tcaacgtagt agacaaggat
    27061 gtggaagact tccacaaact ggcagaaaaa ggtgttaaac ttactgctca gatggttcca
    27121 aatgatccaa tttcagactt tttgagctta ttaaaatagg aaaaaaattt ttaggaggtc
    27181 attgttatga tacaatggtg gcaaatttta cttctcactt tgtactcagc ttatcaaatc
    27241 tgtgatgagt tgacgatcgt ttcatctgca ggttcccctg tatttgctgg tttcattact
    27301 ggtttaatca tgggagatgt gactactggt ttacttatcg gtggtaactt gcaactgttc
    27361 gttcttgggg ttggtacctt cggtggtgct tctcgtatcg acgcaacttc tggtgcggtt
    27421 cttgcgacag ccttctctgt ttcacaagga attgatgcac cgcttgccat tactacaatc
    27481 gctgtaccag tagcagctct cttgacttac ttcgacgttc ttggtcgtat gactactacc
    27541 ttcttcgctc accgtgtgga tgctgcaatc gaacgctttg actataaagg tattgaacgc
    27601 aactacttgc ttggtgcgat tccgtgggct ctatctcgtg cccttccagt cttctttgcc
    27661 cttgcttttg gtggtgcctt tgtacaatca gtagtagact tcgttgaagc ctacaaatgg
    27721 gttgcagatg gcttgacact tgcaggacgt atgcttccag gtcttggatt tgcaatcttg
    27781 cttcgttacc ttccagttaa acgtaacctt cactaccttg ctatgggatt tggtttgaca
    27841 gctatgttga ctgttcttta ctcatatgta acaggtcttg gtggcgctgt tgctggtatc
    27901 gtaggtactc ttcctgctga agttgctgaa aaaattggtt tcgtgaacaa cttcaaaggt
    27961 ttgtctatga ttggtatttc tatcgtaggt attttccttg cagtgcttca cttcaaaaat
    28021 agccaaaaag tagctgtagc agcaccttct acaccatcag aaagtgggga aatcgaagat
    28081 gacgaattct aattacaaac ttacaaaaga agattttaat caaatcaaca aacgtagctt
    28141 gtttactttc caattaggtt ggaactacga acgtatgcaa gcttctggtt acctttacat
    28201 gatcttgcct cagttgcgta aaatgtatgg tgatggaact cctgaattga aagaaatgat
    28261 gaaagttcat actcaattct tcaatacttc accattcttc cataccatta tcgctggttt
    28321 tgaccttgcc atggaagaaa aagatggtgt aggttcaaaa gacgctgtta acggtatcaa
    28381 gacaggtttg atgggaccat tcgctcctct tggggataca atctttggtt cacttgtacc
    28441 tgctatcatg gggtcagtcg cagcaactat ggctatcgct ggccaacctt gggggatctt
    28501 cctttggatt gcagttgcag tagcgtatga catcttccgt tggaaacagt tggaatttgc
    28561 ttacaaagaa ggggttaacc ttatcaacaa catgcaaagt accttgacag ctttgattga
    28621 cgctgcatct gtacttggtg tcttcatgat gggtgctctt gtagcaacag tgattaactt
    28681 tgaaatttct tacaagttgc caatcggtga aaagatgatt gatttccaag acatcttgaa
    28741 ccaaatcttc ccacgtttgc ttccagcaat ctttactgcc tttatcttct ggttgcttgg
    28801 taagaaaggt atgaactcta ctaaagctat cggtattatt atcgtacttg ctttggctct
    28861 ttctgccctt ggtcactttg cacttggaat gtaattcctt atgactaaat cattaatttt
    28921 ggtgagccat ggtcgcttct gtgaggagct tagaggtagc acagaaatga ttatgggccc
    28981 acaagacaac atttacacag tagctcttct tccagaagat ggcccagaag aatttactgc
    29041 taaatttgaa gctgttattg aaggattgga tgatttccta gtttttgcgg atcttctcgg
    29101 tgggacacct tgtaatgtgg tgagtcgctt gatcatggaa ggtcgtgata ttgaccttta
    29161 cgcagggatg aatcttccaa tggtgattga atttatcaat gcgagcctta caggcgcaga
    29221 tgcggactac aagagccgtg ctgcagaaag cattgtgaaa gttaatgacc tgttagcggg
    29281 cttcgatgat gacgaagatg aataatactc ttcgaaaatc tcttcaaact acgtcaacgt
    29341 cgccttaccg taggtatatg ttactgactt cgtcagtctt atccggcaac ctcaaaacgg
    29401 tgttttgagc tgacttcgtc agtcttatcc ggcaacctca aagcagtgct ttgagcagcc
    29461 tgcggctagt ttcctacaga ttttagttgg aactcgattc aattcatgtg acaacgtgaa
    29521 aatcgttaga gcattttata tagaatatac atgggaatgg agcttactcc cattcctata
    29581 tttaatagaa aaagaggaac tcaatgctac attatacaaa agaagacttg ctcgaattgg
    29641 gtgcagaaat cactacgcgt gaaatctacc aacagcctga tgtatggaga gaagcttttg
    29701 aattttatca agcaaaacgt gaagaaattg cagccttcct acaagaaatc gctgataaac
    29761 atgactatat taaggttatc ttgacaggtg ctgggacttc tgcttatgtg ggagacacct
    29821 tgctacctta ctttaaggaa gtctatgacg aacgcaaatg gaatttcaat gctattgcga
    29881 caacagatat cgttgccaat ccagcaacct atttgaaaaa agatgtggca actatccttg
    29941 tgtcttttgc tcgtagtggg aactcgcctg aaagtgtggc gactgttgat ttggccaaat
    30001 ccttggtgga tgagctttat caagtgacga ttacttgtgc aacagatggt aaattggctc
    30061 ttcaagctca cggtgatgac cgtaatctct tgctcttgca accagctgtc tctaatgatg
    30121 ctggatttgc catgacttct agctttacgt ctatgatgtt gacagctctc ttggtctttg
    30181 atcctacaga atttgctgtt aagtctgaac gttttgaagt tgtatctagt cttgcccgta
    30241 aagttttaga caaggcagaa gatgtcaaag agctcgttga tttagacttt aaccgtgtca
    30301 tctatctagg cgctggtcct ttctttggac ttgctcatga agctcagctc aagattttgg
    30361 aattaactgc tggtcaagtt gcgaccatgt atgaaagccc agttggcttc cgtcacggtc
    30421 caaaatctct tatcaacgac aatacagttg ttttggtctt tggtacaacg acagactaca
    30481 ctcgtaagta cgacttggac ttggttcgtg aagttgctgg tgaccagatt gctcgtcgtg
    30541 ttgtgctttt gagtgatcaa gcttttggtc ttgaaaatgt caaagaagtg gcccttggtt
    30601 gtggcggtgt cttgaatgat atttaccgtg tcttccctta catcgtttat gcccaactct
    30661 ttgccctatt gacttcactc aaggtagaaa ataaaccaga tacaccgtct cctacaggta
    30721 cagtaaaccg tgtagtacaa ggtgtcataa ttcacgaata ttaaaagtaa gacagtgttt
    30781 atgaattctt gacaagagga tttgtaaatt atcagataaa ccatagattg tcagtacgct
    30841 ttctatggtt tgtttgcttg agagaaatag taaaaggaga acagaatgaa agcatacaca
    30901 gagcgtgtat ttggaaatgt tgagggcgag gatgtcttgg cctatcgatt tgagacagac
    30961 ggtggctacc aacttgaggt tatgacttat ggcgcgacca tcttgcgcta tgtcgcacct
    31021 gacaaggctg gaaattttgc caatgttatc ttgggatttg atgactttga tagttatgta
    31081 ggcaatagtc ccaagcatgg agcaagtgta ggtcctgtag cgggtcgtat tgcaggtgcg
    31141 acctttgagc tcaatggtaa gacctatgac cttgaggtta ataatgctag caactgtaat
    31201 cacagtggtt caactggttg ggattccagc ttgtttgaag ttgaagaagt aagcgatcat
    31261 ggcttgactc tctacacaga acgtacagat gggacaggag ggttccctgg aaatctcaag
    31321 atttggatca gttatcactt ggaagaaact ggtgcctatg aaattagcta caaggtaacg
    31381 accgatcagg atacgctggt caatccaacc aaccacagct atttcaactt gtctggtgat
    31441 ttcacgcaga cgattgaccg tcatgtcttc caactaaaca cagagggcat ttactcaatc
    31501 actcctgacg gtgttcctgc caaaactcca gaagccaacc gtgatgtggt caaacacatc
    31561 tacaatggta ccttgttgaa ggatatcttt gcagaagaag atgagcaaat ccagctggca
    31621 tcaggtttgg atcacccatt tgcccttcct gtaggccatg acaatgctgg attcctttat
    31681 gaccaaaatt caggtcgctt cctgcttttc aagacagaag ctccttgctt tgtggtctac
    31741 acagcaaact ttgtggatga aagtgtcatc ataggaggtc agccaatgct acagcacaat
    31801 gggattgctc ttgaagcgca agctttacca gatgccattc acagtgacct taaaggccaa
    31861 gtcattctta aagctggtca aaccttcacc agtaagacac gttatgaact tgttgtgaaa
    31921 taaaaaagct ggtcaaaaag tctttaaaat taaaataacg catattgtca ggtgatgaaa
    31981 agtttgatac tatgcgtttt attatgaaat gatttacttt atcttatcct gaaatggtgt
    32041 tatttttgag ttatctggct tgactttctt gatggaaatt atataatagt tgtaataaca
    32101 ataattacaa cgagaaaaga ggaccattta tgacctatga atacaagagt cacatttatt
    32161 tggcagagac agttttaaat gtaaaggatt tggccagtca aacagccttt tatcagcaag
    32221 ttattggttt agaaatctta tctcaaactg agacagagtc cattctaggc cttggtggaa
    32281 aagtcttggt acagctgatt caagcacaag agagcggaga agtgagggaa cattatggtc
    32341 tttaccattt ggccattctc ttgcccacac gcaaggcttt ggctgatgtc ttgaaacacc
    32401 tgacagattt acagattcct cttgtcggcg gtgcagacca tggttacagt gaagctattt
    32461 acttggaaga tttggaggga aatggcattg aactctatcg agataagcca gtttccacat
    32521 gggatattcg agaagatgga cgcattatcg gagtgacgga ggctcttgcg gcgcaggaca
    32581 tttatgagtt gggggaaaga gtagagccct ttatcctggc agaaggtaca agaatggggc
    32641 atattcatct ttccgtcaag gatagtcgaa agtccagcca gttttatcaa aaggtgttag
    32701 ggctagagga taaattcagt gtgcctagcg ctagttggat tgcggctgga gattaccatc
    32761 atcatttagc agttaacgaa tggggaggaa aaggtctggc ttcgcgtaag caaggcttac
    32821 caggtttagc ctactatgtc atcgaagtcg cacataaaga agaactgtta acgattgtcc
    32881 aacgagcaca agaagttgac gcaccaatca aatggatgac atcgagccaa ttggaaatca
    32941 cagactcaga tggcatcgtg acccgtattc gtttagcaag gtaaaattag gaatttctaa
    33001 taagttataa gtattgctag tttgcttttt gaacggtctt tggtaacaga actgcgtgag
    33061 ctggatgggt gagaattttg acaaagaagc tgattagaga tataatgaag aaaaatcgag
    33121 caaggaaaaa gaaatgacaa attcaaagta tattacttgt ttgaaacgtt cagagggcca
    33181 gttgtgtggg attcaaaaga tgattgaagg agatcgtgac tgtgctgata ttgtgacgca
    33241 actgacagca gtgagatcta gtgtagagcg cgtgattgag atgataatta ccgaaaatct
    33301 tactgaatgt atcaatcagc cactagatga ttctgaagct caaaaggaac gcctagaaaa
    33361 ggctatccga tacttgatta aacggaaata aatgaatgtt ttgagacgat atgtgcaaag
    33421 gtctattaac tattagaata gtttaatgtg agtcaaaaga agttgtaaaa aatctttaaa
    33481 attaaaaaaa cgcatagtat caggtgttga atgtactgac ccccaaaagt tagatttttt
    33541 ctgtctaact tttgggggtc agttcataag aaccttggta atatgcgttt tattatgtag
    33601 aaacttatac tcttcgaaaa tctcttcaaa ccacatcagc ttcaccttgc cgtagatatg
    33661 gttactgact tcgtcagttc tatccacaac ctcaaaacag tgttttgagc tgacttcgtc
    33721 agttccatcc acaaccttaa aacagtgttt tgagcagcct gcggctaact tcctagtttg
    33781 cactttaatt ttcattgagt attacttcat cttctcatga aattgagttt ttgcccagct
    33841 cctcttgatt attctacttg accgggccaa gtattcatac caccttctac gttggtaacg
    33901 gtgaggcctt gggagctgag aaattggcag gtagatgcag agcggactcc tccttgacaa
    33961 ataacatagt attcatggtc aggtttgagt tctttgtagc cttgctctaa ggtacttaat
    34021 ggaagatttt tggcacctgg tgcatgtcct gcttggaatt catgtgcttc acggacatcg
    34081 ataagttcta gattttcatt ttagtatttt ccataaaagt cagccatgct gatactagtt
    34141 tccatattct actccttctg ggttagccat tttgtatagt gaataagcgc cgtcaaggtt
    34201 ttggacggta aatcctgctt gcttgaggat aggctctgcg atatagctgc gcaaaccact
    34261 gtggcagctg acgatgtagg cttgtttttt gtccagttca tcagcttcct ccttgacact
    34321 ttgtcagttt ttgatacaat agtacaaaat tagaggaggt gggctatgat tcagaaacat
    34381 gcgattccca ttttagagtt tgatgataat cctcaggcgg ttatcatgcc caatcacgag
    34441 gggttggatt tgcagttgcc aaagaagtgt gtctatgctt ttttaggtga ggagattgac
    34501 cgctatgcga gggaagtagg ggcgaactgt gttggcgaat tcgtttctgc taccaagacc
    34561 tatccagtct atgtcatcaa ctacaagggt gaggaggtct gtctggctca ggctcctgtt
    34621 ggctccgctc cagcagccca gtttatggat tggttgattg gctatggtgt ggagcagatt
    34681 atctctactg ggacctgtgg tgtcctagct gatatagagg aaaatgcctt tctagtccct
    34741 gttcgcgctt tgcgagatga gggagccagt taccactatg tggcaccttg tcgttatatg
    34801 gaaatgcagc cagaggctat tgctgctatt gaggaagttt tggaagacag agggattcct
    34861 tatgaagaag tcatgacctg gacgacagac ggtttttacc gagaaacggc tgaaaaggtg
    34921 gcttatcgta aggaagaagg ctgtgctgtt gtggagatgg agtgttctgc tcttgcggca
    34981 gtagctcaat tgcgtggggt tctctggggt gaattgttgt tcacagcaga ttctctagcg
    35041 gacttggacc agtacgacag tcgtgactgg ggctcggaag cttttaataa ggcgctagaa
    35101 ctgagtttag caagtgttca ccacctttag ttgtacaggc aaaggatttg ttttatcata
    35161 aaatgtctag ctcatacttt tcaaaaatat gtttaaacga ggtcaccttc ctcttgtcct
    35221 aggcatgttg aggttgggaa aaatctttaa aatcagaaaa acgtatcata tcaggtgatg
    35281 aaaattttga tactatgcgt tttatgttgg taagatttag agtgagatga aatgatactc
    35341 ttcgaaaatc tcttcaaacc aggtcagctt caccttgccg taggtatatg ttactgactt
    35401 cgtcagtctt atccggcaac ctcaaaacgg tgttttgagc tgacttcgtc agttctatcc
    35461 acaacctcaa aacagtgttt tgagcaacct gtgactagct ttctaagcga tgccttggtt
    35521 ctcattgcct ataatcaaaa agagaaattt tctcctgaaa agcatataga gtagctggcg
    35581 ttaaaagctc ctgtcttgct tttttgacct atagtcacat ctatcaagta ttgttcttgc
    35641 ctaagctatc aataaaaagg tggcattttt taggcttggt gttagtgaat tttgccttat
    35701 cctatctaag tcatttcgag ctttttatgg tacaatggaa acatgttatt caaattatct
    35761 aaggaaaaaa tagagctagg cttatctcgt ttatcgccag cccgtcgtat ttttttgagt
    35821 tttgccttgg tcattttact aggctctctt cttttgagct tgccctttgt ccaagttgaa
    35881 agctcacgag cgacttattt tgatcatctt ttcactgctg tctctgcagt ctgtgtgaca
    35941 ggtctctcaa cccttccagt agctcacacc tataatatct ggggccaaat aatctgtttg
    36001 ctcttgattc agatcggtgg tctagggctc atgactttta ttggggtttt ctatatccag
    36061 agcaagcaaa agcttagtct tcgtagccgt gcaactattc aggatagttt tagttatgga
    36121 gaaactcgat ctttgagaaa gtttgtctat tctatttttc tcacgacctt tttggttgag
    36181 agcttgggag ctattttgct tagttttcgc cttattcctc aacttggctg gggacgtggt
    36241 ctttttagtt ccatttttct agcgatctca gccttctgta atgccggttt tgataattta
    36301 gggagcacca gtttatttgc ttttcagacc gatttactgg tcaatctggt gattgcaggc
    36361 ttgattatta caggcggcct tggttttatg gtctggtttg atttggctgg tcatgtagga
    36421 agaaagaaaa aaggacgtct gcactttcat acgaagcttg tactattgtt gactataggt
    36481 ttgttgttat ttggaacggc aactactctc tttcttgagt ggaacaatgc tggaacgatt
    36541 ggcaatctcc ctgttgccga taaggtttta gttagctttt ttcaaacagt gacgatgcga
    36601 acagctggct tttctacgat agattatact caggctcatc ctgtgactct tttgatttat
    36661 atcttacaga tgtttctagg tggggcacct ggaggaacag ctgggggact caagattacg
    36721 acattttttg tcctcttggt ctttgcacga agtgagcttc taggcttgcc tcatgccaat
    36781 gttgcgagac gaacgattgc gtcgcgaacg gttcaaaaat cctttagtgt ctttattatc
    36841 tttttgatga gcttcttgat aggattgatt ctgctaggga taacagccaa aggcaatcct
    36901 ccctttatcc acctcatatt tgaaaccatt tcagctctta gtacagttgg tgtaacggca
    36961 aatctgactc ctgaccttgg gaaattggct ctcagtgtta tcatgccact tatgtttatg
    37021 ggacgaattg gtcccttgac cttgtttgtt agcttggcag attaccatcc agaaaagaaa
    37081 gatatgattc actatatgaa agcagatatt agtattggtt aagaaaggaa agagcatgtc
    37141 agatcgtacg attggaattt tgggtttggg aatttttggg agcagtgtcc tagctgccct
    37201 agccaagcag gatatgaata ttatcgctat tgatgaccac gcagagcgca tcaatcagtt
    37261 tgagccagtt ttggcgcgtg gagtgattgg tgacatcaca gatgaagaat tattgagatc
    37321 agcagggatt gatacctgcg ataccgttgt agtcgcgaca ggtgaaaatc tggagtcgag
    37381 tgtgcttgcg gttatgcact gtaagagttt gggggtaccg actgttattg ctaaggtcaa
    37441 aagtcagacc gctaagaaag tgctagaaaa gattggagct gactcggtta tctcgccaga
    37501 gtatgaaatg gggcagtctc tagcacagac cattcttttc cataatagtg ttgatgtctt
    37561 tcagttggat aaaaatgtgt ctatcgtgga gatgaaaatt cctcagtctt gggcaggtca
    37621 aagtctgagt aaattagacc tccgtggcaa atacaatctg aatattttgg gtttccgaga
    37681 gcaggaaaat tccccattgg atgttgaatt tggaccagat gacctcttga aagcagatac
    37741 ctatattttg gcagtcatca acaaccagta tttggatacc ctagtagcat tgaattcgta
    37801 aagagggatg acccctcttt tttgatgccc aagatggcaa atagagacag aagccccttg
    37861 tcttctagta aaagttcttc aaaggctgga ctttatggta aaatagaagg aagtgacaag
    37921 agagagtaat actcaatgaa aatcaaagat caaactagga aactagctgc gggctgctca
    37981 aaacactgtt ttgaggttgt ggatagaact gacgaagtca gctcaaaaca ctgttttgag
    38041 gttgcagata gaactgacga agtcagtaac atctatacgg caaggcgacg ttgacgcggt
    38101 ttgaagagat tttcgaagag tataagaaaa aatcagtccc ctaaaggagc agattatgaa
    38161 gttattgtct atcgccattt ctagctataa tgcagcagcc tatcttcatt actgtgtgga
    38221 gtcgctagtg attggtggtg agcaagttgg gattttgatt atcaatgacg ggtctcagga
    38281 tcagactcag gaaatcgctg agtgtttagc tagcaagtat cctaatatcg ttagagccat
    38341 ctatcaggaa aataaatgcc atggcggtgc ggtcaatcgt ggcttggcag aggcttctgg
    38401 gcgctatttt aaagtagttg acagtgatga ctgggtggat cctcgtgcct acttgaaaat
    38461 tcttgaaacc ttgcaggaac ttgagagcaa aggtcaagag gtggatgtct ttgtgaccaa
    38521 ttttgtctat gaaaaggaag ggcagtctcg taagaagagt atgagttacg attcagtctt
    38581 gcctgttcgg cagatttttg gctgggacca ggtcggaaat ttctccaaag gccagtatac
    38641 catgatgcac tcgctgattt atcggacaga tttgttgcgt gctagccagt tctaactgcc
    38701 tgaacatact ttttatgtcg ataatctctt tgtctttacg ccccttcagc aggtcaagac
    38761 catgtactat ctgcctgtcg atttctatcg ttatttgatt gggcgtgagg accagtctgt
    38821 caatgagcaa gtgatgatta agtgcattga ccagcaactc aaggtcaatc gactcttgat
    38881 agaccaactt gatttgtccc aagtgagtca tcccaaaatg cgagaatatc tgctgaatca
    38941 tattgaactc acgacggtga tttccagtac cctgctcaac cgatctggaa cagcggagca
    39001 tctggcaaaa aaacgccaat tgtggaccta tattcagcag aaaaatccag aagtctttca
    39061 ggctattcgt aagaccatgt tgagccgttt gaccaaacat tctgtcttgc cagatcgcaa
    39121 actgtccaat gtcgtctatc aaatcaccaa atctgtttat ggatttaatt aatataagtg
    39181 ttttataaga gggatttaag aaaaatttta actttttctt agtccttttt aatttcagga
    39241 gattatacta gagtcatcaa ataaagaaag actctaagga gaatcctatg aaattcaatc
    39301 caaatcaaag atatactcgt tggtctattc gccgtctcag tgtcggtgtt gcctcagttg
    39361 ttgtggctag tggcttcttt gtcctagttg gtcagccaag ttctgtacgt gccgatgggc
    39421 tcaatccaac cccaggtcaa gtcttacctg aagagacacc gggaacgaaa gagggtgact
    39481 tatcagaaaa accaggagac accgttctca ctcaagcgaa acctgagggc gttactggaa
    39541 atacgaattc acttccgaca cctacagaaa gaactgaagt gagcgaggaa acaagccctt
    39601 ctagtctgga tacacttttt gaaaaagatg aagaagctca aaaaaatcca gagctaacag
    39661 atgtcttaaa agaaactgta gatacagctg atgtggatgg gacacaagca agtccagcag
    39721 aaactactcc tgaacaagta aaaggtggag tgaaagaaaa tacaaaagac agcatcgatg
    39781 ttcctgctgc ttatcttgaa aaagctgaag ggaaaggtcc tttcactgcc ggtgtaaacc
    39841 aagtaattcc ttatgaacta ttcgctggtg atggtatgtt aactcgtcta ttactaaaag
    39901 cttcggataa tgctccttgg tctgacaatg gtactgctaa aaatcctgct ttacctcctc
    39961 ttgaaggatt aacaaaaggg aaatacttct atgaagtaga cttaaatggc aatactgttg
    40021 gtaaacaagg tcaagcttta attgatcaac ttcgcgctaa tggtactcaa acttataaag
    40081 ctactgttaa agtttacgga aataaagacg gtaaagctga cttgactaat ctagttgcta
    40141 ctaaaaatgt agacatcaac atcaatggat tagttgctaa agaaacagtt caaaaagccg
    40201 ttgcagacaa cgttaaagac agtatcgatg ttccagcagc ctacctagaa aaagccaagg
    40261 gtgaaggtcc attcacagca ggtgtcaacc atgtgattcc atacgaactc ttcgcaggtg
    40321 atggcatgtt gactcgtctc ttgctcaagg catctgacaa ggcaccatgg tcagataacg
    40381 gcgacgctaa aaacccagcc ctatctccac tagg
//
LOCUS       DBEJKC010000014        36513 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.014, whole genome shotgun sequence.
ACCESSION   DBEJKC010000014 DBEJKC010000000
VERSION     DBEJKC010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 36513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36513
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.014"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(272..460)
                     /gene="pneA2"
                     /locus_tag="ACL3G6_000718"
     CDS             complement(272..460)
                     /gene="pneA2"
                     /locus_tag="ACL3G6_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA2"
                     /protein_id="HGR0545290.1"
                     /translation="MKNDFVIGKSLKELSLEEMQLVYGGTDGADPRSTIICSATLSFI
                     ASYLGSAQTRCGKDNKKK"
     gene            complement(467..691)
                     /gene="pneA1"
                     /locus_tag="ACL3G6_000719"
     CDS             complement(467..691)
                     /gene="pneA1"
                     /locus_tag="ACL3G6_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA1"
                     /protein_id="HGR0545291.1"
                     /translation="MTNFNSNEKFCGKSLKSLSADEMSLIYGASDGAEPRWTPTPIIL
                     KSAAASSKICISAAVSGIGGLVSYNNDCLG"
     gene            complement(794..964)
                     /locus_tag="ACL3G6_000720"
     CDS             complement(794..964)
                     /locus_tag="ACL3G6_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhrA family quorum-sensing system peptide"
                     /protein_id="HGR0545292.1"
                     /translation="MRKKRGIKKLVTFALLGVFMFSNTIPYQQFIQKNKQLEIRVQSQ
                     KKSNGLDVGKAD"
     gene            1156..2019
                     /locus_tag="ACL3G6_000721"
     CDS             1156..2019
                     /locus_tag="ACL3G6_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0545293.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEAKELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            2402..3022
                     /locus_tag="ACL3G6_000722"
     CDS             2402..3022
                     /locus_tag="ACL3G6_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545294.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            3108..3551
                     /gene="tsaE"
                     /locus_tag="ACL3G6_000723"
     CDS             3108..3551
                     /gene="tsaE"
                     /locus_tag="ACL3G6_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HGR0545295.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            3541..4059
                     /locus_tag="ACL3G6_000724"
     CDS             3541..4059
                     /locus_tag="ACL3G6_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGR0545296.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQAGGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            4067..5083
                     /locus_tag="ACL3G6_000725"
     CDS             4067..5083
                     /locus_tag="ACL3G6_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGR0545297.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            5168..6424
                     /locus_tag="ACL3G6_000726"
     CDS             5168..6424
                     /locus_tag="ACL3G6_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HGR0545298.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            6479..7645
                     /gene="recA"
                     /locus_tag="ACL3G6_000727"
     CDS             6479..7645
                     /gene="recA"
                     /locus_tag="ACL3G6_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HGR0545299.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            7952..9322
                     /locus_tag="ACL3G6_000728"
     CDS             7952..9322
                     /locus_tag="ACL3G6_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGR0545300.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     YIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            9698..10654
                     /gene="lytA"
                     /locus_tag="ACL3G6_000729"
     CDS             9698..10654
                     /gene="lytA"
                     /locus_tag="ACL3G6_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HGR0545301.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            11032..11193
                     /locus_tag="ACL3G6_000730"
     CDS             11032..11193
                     /locus_tag="ACL3G6_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0545302.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            11180..11386
                     /locus_tag="ACL3G6_000731"
     CDS             11180..11386
                     /locus_tag="ACL3G6_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545303.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            11432..11785
                     /locus_tag="ACL3G6_000732"
     CDS             11432..11785
                     /locus_tag="ACL3G6_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGR0545304.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKKCY"
     gene            11919..12344
                     /locus_tag="ACL3G6_000733"
     CDS             11919..12344
                     /locus_tag="ACL3G6_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545305.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVKEFSLEYMTTGDILVEAFKA"
     gene            12752..13742
                     /locus_tag="ACL3G6_000734"
                     /pseudo
     CDS             12752..13742
                     /locus_tag="ACL3G6_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            13732..14283
                     /locus_tag="ACL3G6_000735"
     CDS             13732..14283
                     /locus_tag="ACL3G6_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545306.1"
                     /translation="MPANTKVIFQETFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYSLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            14342..14602
                     /locus_tag="ACL3G6_000736"
     CDS             14342..14602
                     /locus_tag="ACL3G6_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545307.1"
                     /translation="MRERSATGAQDLSKSIKKHLNDITRLTASLLGDEKLSAIISSSA
                     VKADMHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(15366..15765)
                     /locus_tag="ACL3G6_000737"
                     /pseudo
     CDS             complement(15366..15765)
                     /locus_tag="ACL3G6_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            15890..16348
                     /locus_tag="ACL3G6_000738"
     CDS             15890..16348
                     /locus_tag="ACL3G6_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HGR0545308.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            16361..16969
                     /locus_tag="ACL3G6_000739"
     CDS             16361..16969
                     /locus_tag="ACL3G6_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545309.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            16962..17372
                     /locus_tag="ACL3G6_000740"
     CDS             16962..17372
                     /locus_tag="ACL3G6_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545310.1"
                     /translation="MIKRGDVVALYLPFPTISSDLAVKNHMYICIDNSMTKNKELVKN
                     QTFKPALLTRRLVKNFMIEEPDLARNPFTRPTLIDLDKVFMLDNTVIPTSYLARRRRN
                     VSEELYEEILDHLVQPRLISLNKSEFMQLNPGTY"
     gene            17383..18798
                     /gene="ply"
                     /locus_tag="ACL3G6_000741"
     CDS             17383..18798
                     /gene="ply"
                     /locus_tag="ACL3G6_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HGR0545311.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            19679..20395
                     /locus_tag="ACL3G6_000742"
     CDS             19679..20395
                     /locus_tag="ACL3G6_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0545312.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            20519..20990
                     /locus_tag="ACL3G6_000743"
                     /pseudo
     CDS             20519..20990
                     /locus_tag="ACL3G6_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
     gene            21007..21828
                     /locus_tag="ACL3G6_000744"
                     /pseudo
     CDS             21007..21828
                     /locus_tag="ACL3G6_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            21883..22806
                     /locus_tag="ACL3G6_000745"
     CDS             21883..22806
                     /locus_tag="ACL3G6_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HGR0545313.1"
                     /translation="MVSAKRINQVLDLHSSIQNPAQVQLTDENFKGQVEFKDVTFRYA
                     ANSEAVIEHVSFKAETGQTVAFIGSIGSGKSTLVNLIPRFYDVSAGEILVDGVNVQDY
                     DFSATAHAGQRVAIVGPTGAGKTTIVNLLMKFYEIDKGSIRIDGVDTKAMTRSEVHDA
                     FSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHHFIMTLPDGYDTILDDT
                     VTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQKAMDRLMEGRTSFVIA
                     HRLSTIRNADLILVMKDGNIIEQGNYEELMV"
     gene            22932..23294
                     /locus_tag="ACL3G6_000746"
     CDS             22932..23294
                     /locus_tag="ACL3G6_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HGR0545314.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGEAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            23291..23794
                     /locus_tag="ACL3G6_000747"
     CDS             23291..23794
                     /locus_tag="ACL3G6_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGR0545315.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVFIPATGFVILSLLRKKINAPRPYEEWDIKPLLDRDSPGQSM
                     PSRHVFSATIISMTCLHASLTVGFILLVLSALLGLVRVLGGVHYPKDVVVGYICGLAW
                     GVLFFLF"
     gene            23908..24354
                     /locus_tag="ACL3G6_000748"
     CDS             23908..24354
                     /locus_tag="ACL3G6_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR0545316.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            24360..25034
                     /locus_tag="ACL3G6_000749"
     CDS             24360..25034
                     /locus_tag="ACL3G6_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545317.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLAIIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYVK"
     gene            25195..25386
                     /locus_tag="ACL3G6_000750"
     CDS             25195..25386
                     /locus_tag="ACL3G6_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HGR0545318.1"
                     /translation="MSYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGAMIANDWVKDNGK"
     gene            25393..25473
                     /locus_tag="ACL3G6_000751"
     CDS             25393..25473
                     /locus_tag="ACL3G6_000751"
                     /inference="COORDINATES: protein motif:HMM:NF039231.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545319.1"
                     /translation="MASSGKMLRNTYTPDGYYVGNLGAWQ"
     gene            25671..25970
                     /locus_tag="ACL3G6_000752"
     CDS             25671..25970
                     /locus_tag="ACL3G6_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HGR0545320.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            25967..26284
                     /locus_tag="ACL3G6_000753"
     CDS             25967..26284
                     /locus_tag="ACL3G6_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HGR0545321.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            26300..26926
                     /gene="ytpR"
                     /locus_tag="ACL3G6_000754"
     CDS             26300..26926
                     /gene="ytpR"
                     /locus_tag="ACL3G6_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HGR0545322.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            26959..27720
                     /locus_tag="ACL3G6_000755"
     CDS             26959..27720
                     /locus_tag="ACL3G6_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HGR0545323.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            27798..28193
                     /locus_tag="ACL3G6_000756"
     CDS             27798..28193
                     /locus_tag="ACL3G6_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGR0545324.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            28463..28747
                     /gene="groES"
                     /locus_tag="ACL3G6_000757"
     CDS             28463..28747
                     /gene="groES"
                     /locus_tag="ACL3G6_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HGR0545325.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            28763..30385
                     /gene="groL"
                     /locus_tag="ACL3G6_000758"
     CDS             28763..30385
                     /gene="groL"
                     /locus_tag="ACL3G6_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HGR0545326.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            30523..31278
                     /locus_tag="ACL3G6_000759"
                     /pseudo
     CDS             30523..31278
                     /locus_tag="ACL3G6_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            31725..32498
                     /locus_tag="ACL3G6_000760"
     CDS             31725..32498
                     /locus_tag="ACL3G6_000760"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0545327.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGTGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAN
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            32511..32843
                     /locus_tag="ACL3G6_000761"
     CDS             32511..32843
                     /locus_tag="ACL3G6_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0545328.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADSISKSQLSRFERGENEISL
                     STFFELLSNINVSIENFCNHLEHYKRSERDDFLVNLSPNFYSLNIKGLEVIKNKQQKL
                     FEKSGKNS"
     gene            32935..33366
                     /locus_tag="ACL3G6_000762"
                     /pseudo
     CDS             32935..33366
                     /locus_tag="ACL3G6_000762"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(33724..34257)
                     /locus_tag="ACL3G6_000763"
     CDS             complement(33724..34257)
                     /locus_tag="ACL3G6_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HGR0545329.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(34346..35122)
                     /gene="recX"
                     /locus_tag="ACL3G6_000764"
     CDS             complement(34346..35122)
                     /gene="recX"
                     /locus_tag="ACL3G6_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HGR0545330.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINANQVSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            35160..>36513
                     /gene="rlmD"
                     /locus_tag="ACL3G6_000765"
     CDS             35160..>36513
                     /gene="rlmD"
                     /locus_tag="ACL3G6_000765"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGR0545331.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT        11410 a         6148 c         7757 g        11198 t
ORIGIN      
        1 atttcttcaa aagttttttc agaaataatt gacattgtag aacgccaatt atttaatgaa
       61 aagttattta aggaattatc atttcgttca gataatattt gatatctttc cttaataaac
      121 aatgttttat gcacattttt aattttatat ttcatttact tacctcaaac ctatacgact
      181 tactattgtt ttaaaaaaaa aacctctctc aaaattatta gttacgagag aggaaaataa
      241 agagcaactt ttatttttaa aattgaatat tttatttttt cttgttgtct ttgccacaac
      301 gagtctgagc tgaccccaaa tatgatgcaa taaaacttaa tgtagcagaa catataattg
      361 ttgatctagg gtcagcacca tctgtgccac cataaaccaa ttgcatttct tcaagagata
      421 attctttcaa actctttccg attacaaaat catttttcat tttaatttac cccaaacaat
      481 cattattgta gctaactagc cccccaatac cagaaacagc tgcactaatg catattttcg
      541 agctagctgc agctgatttc aaaataatag gagtaggcgt ccaacgtggc tctgcaccat
      601 cagatgcacc ataaattaaa ctcatttcat cagcagacaa tgattttaaa ctttttccac
      661 aaaatttttc gtttgaatta aagttggtca taagtaataa ctcctcctta taaaaagtta
      721 aataagttgc tctatatttt tcgttttttc agataaatta taattctctc attctcgtgc
      781 aaaatatcgg gttttaatcc gccttcccaa catcaagacc attggacttc ttttgcgatt
      841 gcactcgaat ctccaattgt ttattcttct gaataaactg ttggtaagga attgtattac
      901 taaacataaa aacacctagc aatgcaaatg taactaattt tttaattcca cgtttttttc
      961 tcatgcaatg aaaccccttt ctttttcctt gtttttattc taacagatat attttattta
     1021 gtcaagtatt tttatgtaat ttttaacttt tttttttgtt tattaccata aagaattatt
     1081 tattccttta acttgctatt ttgaactaaa aactttataa tgaaattaag caaataggaa
     1141 ggtttattat ctttaatgaa tacactcgca gagaaattca gattgaaaag aaaagagttg
     1201 agactctccc aacaaactct tgcagaagga atttgtgaac aaagtcagat tagtaaaatt
     1261 gagagagggc atttcattcc ctccgcagac cttttgttca aactctctca acgacttgaa
     1321 gtaccattag attatttttt taatgaacaa attgaaatta aatctaacct ctctaatttc
     1381 aagcaattgt ctgctcgact attagacgat agaaattatg acgatttgga atatatttat
     1441 agaatagaga ttgaacgaag tacttttcta acactagaag accgaactta tcttgaatgg
     1501 attaaagcta ttattgactt ttatcaatat gacagtaagt gtgaagcaat ttcttcattg
     1561 gaaaatatat tattaaaagt ctcctcaaat actctgattt atttaaaggc gttgaatact
     1621 ctatctaatt tctattcctt agtgggtcgt gaacaagaat atgaggcaaa ctactctcat
     1681 ttaatagagt tgtatcagac aaaaaatttg gaccatcaag agtttttatt tggctacatc
     1741 agagttcgtt acaactacgc tcactaccta gtatcaaagg aaaaatataa tgaagccatc
     1801 caagaagctc ttgagacgat tgaactctgt aaacaaagac agacaagcta ccaactggct
     1861 cctctactta ttcttgtagg aaatgctgga gccaaatttc tagacagaga acaagtcaaa
     1921 aattattata tagaagcaaa agagttatgt aagatttata acaatccttt aatgctgatg
     1981 aagatagaaa attatttgaa ggaattagat actgtttagt taatcttgac attatagttt
     2041 ttctgaaacg ttaaataacc tgtaaggctg atagtgaaat gaatactatc agccttatga
     2101 ttatgtgact attagttcgt ctcgctccgt taggtgcgag acaaaaaaaa cacccgctag
     2161 acggattttc atgatttcaa atttatattc ttcgaaaatc tcttcaaatc acgtcagctc
     2221 tatctgcaat ctcaaaacag tgttttgagc aacctgtggc tagctaccta gtttgatctt
     2281 tgattttcat tgagtattag tctctagtgt ttgtttagcg tcttaaagag acatttgaga
     2341 agattagaaa cagttctctc ttttctccta gtataatgat tggtaggaag ggagagagaa
     2401 gatgaaatca atgagaatct tatttttgtt agctttaatt caaatcagtt tgagtagctg
     2461 tttcctatgg aaggaatgca tcttgtcctt taaacaaagt acagcttttt tcatcggaag
     2521 catggttttc gtttcaggaa tctgtgctgg agtaaattat ctttataccc gtaagcaaga
     2581 agtccatagt gtcctagcca gtaagaagtc ggtgaagctt ttttacagta tgttactctt
     2641 aattaatttg ttaggagctg ttcttgtttt gtcagataac ttgttcatca aaaatacgct
     2701 gcagcaagaa ttagttgact ttttattgcc atccttcttt ttcctatttg ggctagattt
     2761 gctgattttt ttacccttga aaaaatacgt gcgcgatttt cttgctatgc tagacagaaa
     2821 aaagacagtg ttggtgacta ttttagcaac acttcttttc ttaagaaatc caatgaccat
     2881 tgtctcactt ctgatttata ttggactggg cttgtttttt gcagcctatc ttgtcccaaa
     2941 ttcggttaag aaggaagttt ccttttatgg tcatattttc cgagatcttg tattggtcat
     3001 tgttacgctc attttctttt agagaaagcc tgttttttat ggatgttatg atgataagtt
     3061 tagtaggaaa atagacacaa aagaaaagtt tttggtataa taagagtatg tacacaaaaa
     3121 atgaagaaga gttgcaagcc ttaggggagc gtttgggcca tctattagca aagaatgatg
     3181 ttttaatctt aactggagaa ctgggtgcag gtaaaacgac ctttactaaa ggacttgcaa
     3241 aaggattaca gatttctcaa atgattaaaa gtcccaccta tactatcgtg agagagtatg
     3301 aaggtcgact tccactttat cacctagatg tttatcgtat tgaaggagat gctgattcta
     3361 tcgacttgga tgagtttatc tttggtggcg gcgtgactgt tattgagtgg ggaaatctct
     3421 taggagatgc cttgccagat gcttatttag aattggaaat tctaaaagaa gcagatggac
     3481 gccgtttaaa ttttcaggca aagggtttgc gtgctgagaa attgttagag gagcttcaat
     3541 atggagtatg aattgctcat tagggaagca gagcccaaag atgcagctga attagtggcc
     3601 tttttaaatc gtgtgagttt ggagacagac tttaccagcc tagacggaga tggtattctc
     3661 ttgactagtg aggagatgga aatattcctc aacaagcaag ctagttcgga caatcagata
     3721 accttacttg cattcttaaa tggcaaaatt gctggtattg taaatattac agctgatcag
     3781 cgtaagagag tccgtcatat tggagatctc ttcattgtga ttggaaaaag atattggaat
     3841 aatggcttgg gaagtttgtt gctagaagaa gcgatagagt gggcacaagc aggtggcatt
     3901 ctgcgtcgtc tccaactgac tgtccaaact cgtaatcaag cagcagtcca tctttatcaa
     3961 aagcatggct ttgtcattga aggtagccaa gagcgtgggg catatataga agaagggaaa
     4021 tttatcgatg tttacttgat gggtaaactg ataggttagt agaaatatgg ttaaaaaaat
     4081 tattggaatg gtgctagctt tactttctgt aactgtagta ggagtaggtg tttttgctta
     4141 tactatttat caacaaggga cagaaacctt agctaaaacc tataaaaaaa tcggcgaaga
     4201 aaccaaggtt attgaagcga ctgaacctct aaccattctg ttaatgggag tggacaccgg
     4261 aaatgctgaa cgaactgaaa cttgggtcgg tagaagtgat agcatgatct tgatgacagt
     4321 gaatcctaaa acgaaaaaaa caacaatgat gagtttagag cgggatattc tgacgcgcat
     4381 tgaatcaggg aatggtcagg ctcatgaagc gaaactgaac tcagcatatg cagatggtgg
     4441 agcagagctt gctatagaaa ccattcaaaa aatgatgaat atccatattg atcgctatgt
     4501 aatggtcaat atgagagggt tgcaaaaact agtggatgca gtaggaggta ttacagtcaa
     4561 taatatccta ggtttcccaa tttctatcag tgaccaagaa gaatttaata ctatttctat
     4621 cggtgttggg gagcaacata ttgggggaga agaagcccta gtctatgcac gaatgcgtta
     4681 ccaagatcct gagggggatt atggtcgtca aaaacgtcaa cgtgaagtta ttcaaaaagt
     4741 catggaaaaa gctctcagtt taaatagcgt tggtcattat caagagattc taaaagcttt
     4801 gagtgacaat atgcagacca atattgattt gtctgcaaaa agtatcccta acttgctagg
     4861 ctataaagat tcatttaaaa ccattgaaac tcagcagttg cagggtgaag gagagatact
     4921 tcaaggtgtt tcttaccaga ttgtttcgag agcacatatg ttggaaatgc aaaatatact
     4981 ccgacgttct ttgggacaag aagaagttac tcagcttgaa accaatgcgg ttttatttga
     5041 agatttattt ggcagagcac ctgttggtga tgaagataat taacttttga tacaaataaa
     5101 aaaatcaatc gtaggaaaat tcctgcgatt ttttcaaaaa aatacgaata gataggtagg
     5161 aggaaacatg aaagcagaaa tcattgctgt tggaacagag attttgacag gacagattgt
     5221 caacaccaat gcccagtttt tgtcggaaaa actagctgag attggggtag atgtatattt
     5281 tcagacggct gtaggagaca atgaagttcg tctcttgtct ttgcttgaga ttgccagtca
     5341 acgtagcagt ctggtgattt tgacaggcgg tttggggcca actgaggacg acctaaccaa
     5401 acaaacccta gctaaatttt tagggaaagc attagtcttt gatcctcagg ctcaggagaa
     5461 gttggatatc ttttttgccc tgcgaccaga ctatgcccga acaccgaata acgaaagaca
     5521 agctcaaatt gtagaaggag cgattccact gccaaacgaa acaggactgg ctgttggagg
     5581 aaaattagaa gtagacggag tgacctatgt cgtccttcca ggtccgccaa gtgaattgaa
     5641 acccatggtc ttaaaccaac ttctacccaa gttgatgaca gggagcaagc tgtattcccg
     5701 agttcttcgt ttctttggga ttggcgagag ccagttggtt acgattttgg ctgatttaat
     5761 tgataatcag atcgatccta ccttggcccc ttatgccaag acaggagaag tcactctacg
     5821 tctgtcaaca aaggctagca gtcaagaaga ggcgaatcaa gcgctggata tcttggaaaa
     5881 tcaaatcttg gactgccaga ctttcgaagg aatttcttta cgagactttt gctatggtta
     5941 tggggaagaa actagtttag ccagcattgt ggtagaagaa ctgaaaaggc aagggaaaac
     6001 catcgcggct gcagagagtt tgacggcagg tcttttccaa gctaccgtgg cgaatttttc
     6061 tggagtttca agtatattta agggtggttt tgtgacctat agcttggagg aaaaatcaag
     6121 gatgttggat attcctgcca agaatttgga agaacatggt gtggtgtctg aatttacagc
     6181 tcagaagatg gctgagcagg cacgaagcaa gacccagtct gattttggaa ttagtttgac
     6241 cggagtggca ggaccagata gcctagaagg acacccagtt gggacagtct tcataggctt
     6301 ggcgcaagag caaggaactg aggttatcaa ggttaatatt ggaggcagaa gccgagcaga
     6361 tgtacgtcat attgcggtta tgcatgcctt taacctagtt cgcaaggctt tattaagtga
     6421 ctaacttttg atataatagt agataggtct gaggatcatt agaatgtagg agaatagaat
     6481 ggcgaaaaaa ccaaaaaaat tagaagaaat ttcaaaaaaa tttggggcag aacgtgaaaa
     6541 ggccttgaat gacgctctta aattgattga gaaagacttt ggtaaaggat caatcatgcg
     6601 tttgggtgaa cgtgcggagc aaaaggtgca agtgatgagc tcaggttctt tagctcttga
     6661 cattgccctt ggctcaggtg gttatcctaa gggacgtatc atcgaaatct atggcccaga
     6721 gtcatctggt aagacaacgg ttgcccttca tgcagttgca caagcgcaaa aagaaggtgg
     6781 gattgctgcc tttatcgatg cggaacatgc ccttgatcca gcttatgctg cggcccttgg
     6841 tgtcaatatt gacgaattgc tcttgtctca accagactca ggagagcaag gtcttgagat
     6901 tgcgggaaaa ttgattgact caggtgcagt tgatcttgtc gtagtcgact cagttgctgc
     6961 ccttgttcct cgtgcggaaa ttgatggaga tatcggagat agccatgttg gtttgcaggc
     7021 tcgtatgatg agccaggcca tgcgtaaact tggcgcctct atcaataaaa ccaaaacaat
     7081 tgccattttt atcaaccaat tgcgtgaaaa agttggagtg atgtttggaa atccagaaac
     7141 aacaccgggc ggacgtgctt tgaaattcta tgcttcagtc cgcttggatg ttcgtggtaa
     7201 tacacaaatt aagggaactg gtgaccaaaa agaaaccaat gtcggtaaag aaactaagat
     7261 taaggttgta aaaaataagg tagctccacc gtttaaggaa gccgtagttg aaattatgta
     7321 cggagaagga atttctaaga ctggtgagct tttgaagatt gcaagcgatt tggatattat
     7381 caaaaaagca ggggcttggt attcttacaa agatgaaaaa attgggcaag gttctgagaa
     7441 tgctaagaaa tacttggcag agcacccaga aatctttgat gaaattgata agcaagtccg
     7501 ttctaaattt ggcttgattg atggagaaga agtttcagaa caagatactg aaaacaaaaa
     7561 agatgagcca aagaaagaag aagcagtgaa tgaagaagtt ccgcttgact taggcgatga
     7621 acttgaaatc gaaattgaag aataagctgt taaagcagtg gagaaatccg ctactttttc
     7681 gatttttgat tcaagttttt agattatata tagtagattg aaataagata tgaacaactt
     7741 tattaggaaa gtcaaattaa tttctagaaa tgttttagca gctacagcgt actattccaa
     7801 actcaaccaa ctataataga tcgaaactag aatagtacac atctacttct aaaacattgt
     7861 taaaaatcga tttgactgtc cttatttcat tccgctatat ataagtttgc tgtttcttgt
     7921 cgctcctctg gaaagctgat ataatagctt tatgaataaa aaacgaacag tggacctgat
     7981 acatggtccg attcttccct cgctcttaag cttcaccttt ccaatcttgt tatcaaatat
     8041 ttttcaacag ctctataaca ctgctgatgt cttgattgtt ggacgatttc ttggtcaaga
     8101 atccttggct gcagtaggag cgacgacagc gatttttgat ctgattgtag gttttacact
     8161 tggtgttggc aatggcatgg ggattgtcat tgctcgttat tatggggctc ggaatttcac
     8221 taaaatcaag gaagcagtag cagccacctg gattttaggt gctcttttga gcattctagt
     8281 tatgttgctg ggctttcttg gcttgtatcc tctcttgcaa tacttagata ctcctgcaga
     8341 aattcttcct caatcttatc aatatatttc tatgattgtg acctgtgtag gtgtcagctt
     8401 tgcttataat ctttttgcag gcttgttgcg gtatattggt gacagtctag cagccctggg
     8461 atttctgatt ttctctgcct tggttaatgt ggttctggat ctctatttta ttacgcaatt
     8521 gcatctggga gttcaatccg caggacttgc taccattatt tcgcaaggtt tatcagcggt
     8581 tctctgcttt tattatattc gtaaaagtgt gccagaactc ttgccacagt ttaaacattt
     8641 caaatgggac aaaagcttgt acgcggatct cttggagcaa ggtttggcta tgggcttgat
     8701 gagttcaatt gtatctatcg gcagtgtgat tttacagttt tctgttaata catttggtgc
     8761 agtgattatt agtgcccaga cggcagctcg acgcattatg acctttgccc ttcttcctat
     8821 gaccgctatt tctgcatcaa tgacgacctt tgcttctcag aatctaggag ctaagcgacc
     8881 tgaccgcatt gttcaaggtc ttcgaatcgg cagtcgttta agtatatcct gggcagtttt
     8941 tgtttgtatt ttcctctttt ttgccagtcc agccttggtt tccttcttgg ctagttcgac
     9001 agatggttac ttgatagaaa atggaagtct ctatctgcaa atcagttcag ccttttatcc
     9061 cattttgagc ctcttgttga tttatcgcaa ttgcttgcag ggcttggggc agaagatcct
     9121 tcctctagtt tctagcttta ttgaactaat cggaaaaatc gtttttgtgg ttttgattat
     9181 tccttgggca ggatataagg gtgttatcct ttgtgaacct cttatctggg ttgccatgac
     9241 agttcaactg tacttctcac tattccgtca tcccttgata aaagaaggaa aggcaatttt
     9301 ggcaaccaaa gtgcaatcct agttggattt actgaataaa atccatttcc tctagtgaac
     9361 atcgaaaaaa cttgtgttct cttcttcagt ttggtgttga aaatagttta acagactttt
     9421 gacttctttt atatgatata ataaagtata gtatttatga aaaggacata tagagactgt
     9481 aaaaatatac ttttgaaaag ctttttagtc tggggtgtta ttgtagatag aatgcagacc
     9541 ttgtcagtcc tatttacagt gtcaaaatag tgcgttttga ggttctatct acaagcctaa
     9601 tcgtgactaa gattgtcttc tttgtaaggt agaaataaag gagtttctgg ttctggattg
     9661 taaaaaatga gttgttttaa ttgataagga gtagaatatg gaaattaatg tgagtaaatt
     9721 aagaacagat ttgcctcaag tcggcgtgca accatatagg caagtacacg cacactcaac
     9781 tgggaatccg cattcaaccg tacagaatga agcggattat cactggcgga aagacccaga
     9841 attaggtttt ttctcgcaca ttgttgggaa cggttgcatc atgcaggtag gacctgttga
     9901 taatggtgcc tgggacgttg ggggcggttg gaatgctgag acctatgcag cggttgaact
     9961 gattgaaagc cattcaacta aagaagagtt catgacggac taccgtcttt atatcgaact
    10021 cttacgcaat ctagcagatg aagcaggttt gccgaaaacg cttgatacag ggagtttagc
    10081 tggaattaaa acgcacgagt attgcacgaa taaccaacca aacaaccact cagaccatgt
    10141 ggatccatac ccttacttgg caaaatgggg cattagccgt gagcagttta agtatgatat
    10201 tgagaacggc ttgacgattg aaacaggctg gcagaagaat gacactggct actggtacgt
    10261 acattcagac ggctcttatc caaaagacaa gtttgagaaa atcaatggca cttggtacta
    10321 ctttgacagt tcaggctata tgcttgcaga ccgctggagg aagcacacag acggcaactg
    10381 gtactggttc gacaactcag gtgaaatggc tacaggctgg aagaaaatcg ctgataagtg
    10441 gtactatttc aacgaagaag gtgccatgaa gacaggctgg gtcaagtaca aggacacttg
    10501 gtactactta gacgctaaag aaggcgccat ggtatcaaac gcctttatcc agtcagcgga
    10561 cggaacaggc tggtactacc tcaaaccaga cggaacactg gcagacaagc cagaattcac
    10621 agtagagcca gatggcttga ttacagtaaa ataataatgg aatgtctttc aaatcagaac
    10681 agcgcatatt attaggtctt gaaaaagctt aatagtatgc gttttcttgt ggagatattt
    10741 ccttcaattt ttgctactat attaaacaaa aatcaaaaag caaactagaa agttatgctc
    10801 aaataaaatc taaatttgac aatgtaaacc gagtcggata gctttaagta ctgttttgag
    10861 gttgaagata cgatttttga taggaactca tcaaataggt ttaatatcat caattttaga
    10921 tttttaagta gcatcaataa attgcttcct tgttttgtca taattttttt atttaaaaaa
    10981 ttatgacaag agtgtgctat tctttttatg agaggtgtat gaatatgata aatgtatgtg
    11041 ataaatgtat gtgatgttgg aaaaagaata aaagaactta gaatatcttc aaatcttact
    11101 caagataaga ttgctgagta tttgtctttg aatcaaagca tgattgccaa aatggaaaaa
    11161 ggtgaaagga atatcacgaa tggatttaag taataaagct ccaaatctta gaaaaaagtt
    11221 gggagctgat ggtgaatcgc cgatagatat ttttaaattg gtacaaaaga tagaaaattt
    11281 gacgctggta ttttatggac tcggaaagaa tattagcgga gtctgttata aaggaactca
    11341 gttcagtctc attgcagtca attcagacat gtcattagga aggtaaagat tttctttagc
    11401 acatgaactg tatcatcttt attatgatga ggtgaagaag agttcagtca gtcttatctt
    11461 gattggtgaa ggagatgaaa ctgaaagaaa agcggatcag tttgcttctt attttttaat
    11521 tttcccatct tcactgtata ggatggttga ggaaatcaga gaaaatgcca atagaactca
    11581 tcttgaagta gaagatatta taaaattggg tcagttttat ggtatcagtc ataaagctat
    11641 gttatataga ttgaggaatg atggatacct tgatgcagaa gaaattaaaa atatggatat
    11701 tagtgttata gagacagctt caagattagg ctatgataca agtttatatc gtcctttgtc
    11761 agaaagtaaa aagaaatgtt attaggataa tatattaatc taactgaaca acttttagaa
    11821 aataacagaa tttcgcaagg gaagtatgag gaactgttac tagatgcttt cagatatgat
    11881 attgtatatg ggctagatga agagggggga gttgtcgttt gactagtcgt gtatttattg
    11941 atgcagattg tatttcagta tttttatggg ttggcactga acatctttta gaaaagctct
    12001 atttgggtaa aattgttatt ccacaagagg tgtatgatga aatcaatata cctacaattc
    12061 cccatttaaa atctaggata gatcagttgg tagctaaggg ttcagctgag attgtgagca
    12121 tagacattgg aactgaagaa tacgcattat atagagattt aacaagaaat catgatagta
    12181 acaagattat tggtaaggga gaagcggctt ctatttcctt agcgaaaaag cataatggga
    12241 tattaggaag taataaccta agagatgtta aatcatatgt aaaagaattt tctttagaat
    12301 atatgacaac aggagatata ctggttgaag cgtttaaagc gtaatttatt actgaacaag
    12361 agggcaatca tatctggaat aatatgctta aaaagagaag gaaaattggt gcaaattcat
    12421 tttcagacta tcttcgtgga agtattcatc aaaatagaca aaaataaatt tggataaatc
    12481 gaactcacta ttcaggaggc atatgagcaa ttcgaaaaag aaaagtgtca aattgagcct
    12541 ataggagtag aagtgaaata gtaagtcctg catagtggat gagagaaaag ttctccttga
    12601 agttttcctg aactatcagt cgcatgtcaa acgatatgta gggtaatgtg agaggggata
    12661 gcgagtagtt tttggttatt ttatcaaaaa acttatattt tattataccg aatgataaaa
    12721 tataataaaa atgatagaat aaggaaaaaa catgaatgtc aaaaagataa tgtcaatttt
    12781 tcaatccttt tatgttgatg tcagtattga ggaactgact ttaccaatca gttttgtaaa
    12841 aaagtttgag tatactcaaa tgacttttca taaggaatca tttttattga ttaaagaaaa
    12901 gagaaggggg agtttgagtt catttgttac tcaggctcgc actatgggtg ataaagccaa
    12961 tatggatgtt gttttggtgt tttcgaagtt atcagacggt gaaaaaaaag caattacttc
    13021 aagctagagt tccgtttgta gactttaagg gaaacctctt cttccctaca ttgggactag
    13081 tactgaatgc gaatgatact gaagtcccta aggaattaat acctagcgaa caattaacgt
    13141 ggattgcctt tttattgaca aaaggtcaaa aagtagtaga tgttgatttg ctttcacaag
    13201 tcactggact tccaaactca acaatttata ggtgtttgag gacttttaaa gctttatatt
    13261 tgttaaacaa gcaaaataag ctttacacat atacggtgtc aaagaaagaa ttattcttaa
    13321 aatccgtgtc atgtttattt aatcccatca aaaaacggat tttattgcca gatggcgata
    13381 taaagcagat aaaatctgtt tctaaccttc tatatggtgg tgcttatgct ttgtcgcatt
    13441 caactttttt agctgaaacg gatgaaaata ttagctatgt catatggcag agaaaattca
    13501 atcagttacc cttgccactt tctcagcata ttttaaaagg aaagatgcta gagatatgga
    13561 aatatcgtcc ttttgtatct gagttttgga atgattttaa aaataatcat gataaacaat
    13621 ttgtagatcc gatttctctt tatttgacct taaaagatga tgatgaccca cgtatagagg
    13681 aagagagtga agcactagaa aatatgatat tacagtatct gggagaagat gatgccagct
    13741 aatacgaaag ttatttttca agaaacgttt gcggattttc agaactatta tgttctgatt
    13801 gggggaactg ctacctctat cgtattggat tcgcaaggat ttaaaagtcg cacaacaaaa
    13861 gattatgata tggtcatcat tgatgaagta aaaaataagg aattttatac taccttgaat
    13921 cattttttag aattgggaga gtatcaagga agtcagaaag atgagaaagc gcagcttttt
    13981 cgatttacaa caactaatcc tgagtttcct tctatgattg aactatttag tatcttacca
    14041 gaatattcat taaagaagga cggtcgagaa attcccttac attttgacca agatgctagt
    14101 ttatcagcct tattattgga tgaagattat tataatatat tggtgcatga aaaagaaacc
    14161 attcaggggt attcggtatt gagtaattgt ggtctatact cttcgaaaat ctcttcaaac
    14221 cacgtcagct tccatctaca acctcaaaac agtgttttga gcagcctgca gctagcttcc
    14281 tagtttgctc tttgattttc attgagtatt aattattttt aaggctaaag cttggctgga
    14341 tatgagagag cgctctgcta caggtgctca agatttaagt aagtccatta aaaagcattt
    14401 gaatgacatt acccgtttga cagcttcctt gctaggagat gaaaagttat cggctataat
    14461 atcaagtagt gcggtaaaag cagacatgca ccgctttgtg atagaattag agcctgtgaa
    14521 gtcaactatt cttcaaaatg atgacatttc attggatcaa aatgaaattt ttgaaattct
    14581 gaaaaatttt ctcgatggtt aaaataattg tagcgagatg gctatattga attcgtctat
    14641 atctggaaac tagaaaaaac ttcaatttca ggagaaaatg aagtcaatct tcccacaatc
    14701 aaacgtatag tatcaaggtt tttcaagacc tgatattatg cgttttttgc ttttcaaaac
    14761 tttttgccca gtctttgttt ttatcctcta gtcacttgat ttgtttcagg tggtttttta
    14821 gtatagtaaa atgaaacgag aacaggacaa attgatcagg acagtcaaat cgatttctaa
    14881 caatgtttta gaagcagaag tgtactattc tagtttcaat ctactatagt taaatctgcg
    14941 gtcaagtcta ctggtgaatc tatgattgta atactcttcc aaaatctcat caaccacgtc
    15001 agtcttgcct tgcagtctgt atcttactga ccaagctagt gatggactta gaataggtga
    15061 tttggagcgt cctattggct aggaaatgct gatcatagtc ctttgctgag gctagggtgt
    15121 ttcaacattc aacactcaac tggttgatct agttgatagg aagggaatta ctataaaata
    15181 ctcaggcttc catcatattt tttgaaacga ttgtgtaatc aaaatgtacc aatattgtag
    15241 tattggtaca gaagatgttg tgaatggata aatatatcat aactgctgtc tctctatgta
    15301 aaaagaaggc tgtatcaaaa agatttcata tgtctgtgca tatatataat agacttcctg
    15361 caaaactaga atcctagttc atgattgata ataccagcac tcaaattcat tcgtaatccg
    15421 aagcgtttac gatgatttcg acaggttgtt gaaaacattt taaacgtttt tactttggca
    15481 aagatgttct caaccttgct tctctcctta gatagcgcat ggttatagac tttatcttca
    15541 actgttagtg gcttgagttt gctggattta cgtggagttt gtgcttgagg atatatcttc
    15601 atgagccctt gataattact gtcagccaag attttaccag cttgtccgac ttttttgata
    15661 agctgttttt aatacagcta acatctcttc aaaagtggta cgctgaacac caacaagacg
    15721 cttaaatcgt gtatcagtta attgtttact tgcttcataa ttcatagaac tactatacca
    15781 tattttgttt cgcagggagt ctaataagtt atagtccagt ttttactata ctttgatatt
    15841 caaatatgtt atactatggt tatcaaagta aatgaaagga gttacgaata tgacgccaga
    15901 agaaatgtac ctgacagagc gattagacgt acagatagct cattttttaa agaaaagcgt
    15961 tcaacatcgt aggcgctata aggtattaaa aataacagaa atcgtggcag gtttcctcat
    16021 agctgtcttt tgtgctattc ctatgccagg tgatcgctac cgtttgattt cggttgcctt
    16081 atccagtctc ggcttgctgt gtgaggggat tatcaatttg tataatgcaa aggaaaattg
    16141 gatttcttac caaaaaactg cgcaactcct ggagaaagaa aaattcctct atcaatgcca
    16201 aacggagaaa tatgcaggaa agaccaaggc ttttgcccta tttgtcaaga catgcgaagg
    16261 tcttatctca gaggagatta accagtggga aagtatccag tcaaaagaag tggcagctag
    16321 tgcagatgct ccagttaaaa aagagtagga ggtagaggaa atgtctcaat ccagctacct
    16381 gtcgcccttg ctctggttaa aaaaagaagc cgataaggaa aagatgagcg cgacccagtg
    16441 ccagatattt ttcttttact atcaaatgtt tgagctctta tttgctagag aaagcgacat
    16501 gaaagactta tgtctgggaa cgaaaggttt ttatttctcg cagttagaga aaaatttgct
    16561 ttctggagtt tcccgatttc taaaaaactt ggaggggaaa gtaactctca aggctaacca
    16621 agaagtatca gctcgcaaag ccctttttct agccttgaca actagccaat cagattggca
    16681 ggagttagct cctgtttttg atttttatca gactatcggg aggcttgaaa atccttctct
    16741 cttgagttct caggacagac aacatctgat gtggatttac cagtcagctt tggagaagga
    16801 ttatattgtc aaggttattg gcgacaagca ttttgtattg aagagacaag atgctactaa
    16861 attgacagcg cgccaaactc aaactttgga aattctgagt caatcagaag acttggtcaa
    16921 tcctgtctat gttacattag gagaaaaggg ggtgctcttg cttgattaag agaggagatg
    16981 ttgtagctct ttatttgcct tttccgacta ttagtagcga tttggctgtg aagaatcata
    17041 tgtatatctg tattgacaac agcatgacta aaaacaaaga gttggttaaa aatcagacct
    17101 tcaaaccagc tctcttgacc agacgtttgg tcaagaactt tatgatagaa gagccggatc
    17161 tagctcgtaa tccttttaca agaccaacct tgattgactt agataaggta tttatgttgg
    17221 ataatacggt tattccgact tcttatctag ccagacggcg acgcaatgtc tcagaagaat
    17281 tgtacgagga aattttggat cacttagtcc aaccacggct gatttcgctg aacaagtctg
    17341 agtttatgca actcaatcca ggaacttatt aggaggtata agatggcaaa taaagcagta
    17401 aatgacttta tactagctat gaattacgat aaaaagaaac tcttgaccca tcagggagaa
    17461 agtattgaaa atcgtttcat caaagagggt aatcagctac ccgatgagtt tgttgttatc
    17521 gaaagaaaga agcggagctt gtcgacaaat acaagtgata tttctgtaac agctaccaac
    17581 gacagtcgcc tctatcctgg agcacttctc gtagtggatg agaccttgtt agagaataat
    17641 cccactcttc ttgcggtcga tcgtgctccg atgacttata gtattgattt gcctggtttg
    17701 gcaagtagcg atagctttct ccaagtggaa gaccccagca attcaagtgt tcgcggagcg
    17761 gtaaacgatt tgttggctaa gtggcatcaa gattatggtc aggtcaataa tgtcccagct
    17821 agaatgcagt atgaaaaaat cacggctcac agcatggaac aactcaaggt caagtttggt
    17881 tctgactttg aaaagacagg gaattctctt gatattgatt ttaactctgt ccattcaggc
    17941 gaaaagcaga ttcagattgt taattttaag cagatttatt atacagtcag cgtagatgct
    18001 gttaaaaatc caggagatgt gtttcaagat actgtaacgg tagaggattt aaaacagaga
    18061 ggaatttctg cagagcgtcc tttggtctat atttcgagtg ttgcttatgg gcgccaagtc
    18121 tatctcaagt tggaaaccac gagtaagagt gatgaagtag aggctgcttt tgaagctttg
    18181 ataaaaggag tcaaggtagc tcctcagaca gagtggaagc agattttgga caatacagaa
    18241 gtgaaggcgg ttattttagg gggcgaccca agttcgggtg cccgagttgt aacaggcaag
    18301 gtggatatgg tagaggactt gattcaagaa ggcagtcgct ttacagcaga tcatccaggc
    18361 ttgccgattt cctatacaac ttctttttta cgtgacaatg tagttgcgac ctttcaaaat
    18421 agtacagact atgttgagac taaggttaca gcttacagaa acggagattt actgctggat
    18481 catagtggtg cctatgttgc ccaatattat attacttggg atgaattatc ctatgatcat
    18541 caaggtaagg aagtcttgac tcctaaggct tgggacagaa atgggcagga tttgacggct
    18601 cactttacca ctagtattcc tttaaaaggg aatgttcgta atctctctgt caaaattaga
    18661 gagtgtaccg ggcttgcctg ggaatggtgg cgtacggttt atgaaaaaac cgatttgcca
    18721 ctagtgcgta agcggacgat ttctatttgg ggaacaactc tctatcctca ggtagaggat
    18781 aaggtagaaa atgattagga gagaagaatg tttgcgacaa aaagaggcga tgagctctct
    18841 gcgaatatct gaaagtttat ctcttgccta gcgatttcca ttggagtatg ctcgtgatgt
    18901 taaaatgaat ctatcaaaca gaatgtgtaa aaaagtaaaa agggtagcca attccttgat
    18961 atacagggga ttgattatcc tttacttgtt ttagatgatt ggaaattcaa gaatgacacg
    19021 tatcggaaat attttgctgt ttatatctaa tacccattta tggaaaaaat gaaattaaat
    19081 atgaacaaat caattgctag caatggttta gaagtgccag tgtactagtc taatttctcc
    19141 atcttgggaa cacgtaaatt atactcttcg aaaatctctt caaaccaggt cagtcctatc
    19201 cgcaacctca aaacagtgtt ttgagcaacc tgcggctagc tttctagttt gctttttgat
    19261 ttttattgag tattagaggt ttgcttagaa actcttctat tgatttctta gaatacaata
    19321 gcgcctataa gaactgttga atttcaaagt atttacttga actatgatat gtctggagta
    19381 gactgtcaac aaaaggtgca gtatgattgt ttttgtcgct tatatctaca aacttcaaac
    19441 agtaatttga gctgactttg tcaaacttgg ctgaaacttt ctatttgcag ataatggtct
    19501 agtttgtttt ttgaatgtgg atgagtgtct gttgataaag atagaaaggc aagaccatct
    19561 tagcaggtaa agtgctatcc tagcttgatt tgctaataaa atccatttcc tctagtgaaa
    19621 atcaaaaaaa cttgtgttat aataagaaag attaaaatgt gaaaaaagga gattcctaat
    19681 gggacgtaaa tgggccaata tcgtagccaa gaaaacggct aaagatggag ctaactctaa
    19741 agtatatgca aaatttggtg tagaaatcta tgtagcagct aaaaaaggtg atccagatcc
    19801 agaatcaaac tcagctttga aattcgttat cgaccgtgct aaacaagccc aagtgccaaa
    19861 acacattatc gataaagcga ttgataaagc caaaggaaac acagacgaaa cctttacaga
    19921 aggacgttac gaaggttttg ggccaaatgg ctctatgcta attgtggata ctttgacttc
    19981 taacgttaac cgtacagcag ccaatgtccg tgcagccttt ggtaaaaacg gcggaaacat
    20041 gggcgcttca ggttctgttt cttacctttt tgacaacaaa ggtgttattg tatttggagg
    20101 tgaagatgcg gacgcagtct ttgagcaatt gctcgaagcg gatgtggatg tggatgacgt
    20161 agaagcacaa gaaggtacaa tcacagttta cacagcgcca actgaccttc acaaggctat
    20221 cgttgctctc cgtgagtctg gtattgaaga attccaagtg actgaattgg aaatgattcc
    20281 tcagtcagaa gtggaattgt caggcgaaga ccttgaaacc tttgaaaaac tttacagcgt
    20341 tcttgaagac gacgaagacg tccaaaagat ttatacgaac gtagatgggt tttaatttaa
    20401 cctatagaac atgatcctaa gtgagaaaat cacttgggat ttttttaatc aagaaaatag
    20461 ttctcataga aatttaatta ttctccagag aactattttt atttagaagg gggagattat
    20521 ggataaaccg atgttagtct ttaagcgttt tggtcatcaa atttacctga tggtgcaaaa
    20581 ggaagccaaa cgttgcggca ttgaatttat gggtgggccg caaggtcagg ttgtgcgttt
    20641 tttggataat cgctagaaaa atcaagactt ggtcttgatt aaagatatcg agcaggaact
    20701 caatattacc aagtctgttg ctagtaatct ggttaagcgt atagtgcaaa atggtttggt
    20761 ggaattggag gcgagtcctg ttgataagcg ggctaagttt gttcgtctga cggacaaagc
    20821 acgttctcag atgcaacagg ttaaggcttt ttttgaacgc atagacaagc agttgatgga
    20881 agacattgat gaagatgaat tactgatttt tgagaaagtt ctcggtcaac tacaggcaaa
    20941 atatcaaggg aataggagga gagaataaag aaattaacca aaagaattag tagaaaagaa
    21001 tgggggatga ttttactagc cattctcttt acttgctttt cggtctatct agagttggaa
    21061 gtgccgacct atatctcgaa aattacggat ttgctaggta gtcaagaaac taatttagat
    21121 gagttgtggc agccggcaag catgatgatg ggaatgccct ttcttgcctt cttgtccgta
    21181 gttgcagttg gattttttgc atcccgagtg gcggcttctt atactagtag gctgagaagt
    21241 gatattttta accgagtttt ggattactcg cagacagaga ttaagaaatt ttcaattcct
    21301 agcctcttga tgcgtactac caatgacatt actcaagttc aaatgttgat tactatggac
    21361 ttgcaagtgg taacgtgtgg tccaattatg gctatctggg ctattgggaa gattttaggt
    21421 cattcagaat actggctctg ggccgtactt gtggcagtga ttgtcaacgt cctgatgacg
    21481 accgttttga tgacgctagc ctttccaaaa cagtccttga ttcaggggct gacagataaa
    21541 ctgaacagta tcactcgtga gagtttaaca ggtattcgtg tcgttcgtgc ctacaatgca
    21601 gaggattatc aaaatgaaaa atttgcagca gtaaatgatg aattgacccg ttaaaatttg
    21661 tttgtcaacc gtcttatggc tattttgaat cctatcatga tggggatttc aagtggtttg
    21721 agtgtggcga tttactggat tggggcctat gtgattaacg acgctgctcc gatagcgcgt
    21781 ctgcctctct ttagtgacat gattgttttc atgtcttatg ccatgtaggt tgtcatggac
    21841 ttccttctca tgggagcact cttcatcgtt cttccccgaa ctatggtctc tgctaagcgg
    21901 attaatcaag ttttagattt gcattcttct atccaaaacc ctgctcaagt gcagctgact
    21961 gatgaaaact tcaaaggtca ggtcgagttt aaggatgtga ccttccgcta tgcggcaaat
    22021 tcggaggcag ttattgaaca tgttagcttt aaagcagaaa ctggtcaaac agtggccttt
    22081 attgggtcaa taggttctgg taaatcaact ctggtcaatc tgattccacg tttctacgac
    22141 gtgtcagcag gagaaattct ggtggacggt gtcaatgttc aagactatga cttctctgcg
    22201 acagctcatg ctggtcaaag ggttgccatt gttgggccga ctggggctgg taagacaacc
    22261 attgtcaatc ttttgatgaa attctatgag attgataagg gaagtattcg cattgatggt
    22321 gtggatacca aggctatgac gcgttcagaa gtgcatgatg ccttttcaat ggtcttgcag
    22381 gatacctggc tctttgaagg aactattcga gacaatctca tctataatca aatagggatt
    22441 agtgatgaac gaatgatgga agctagtaag gctgtgggaa ttcaccactt tattatgacc
    22501 ttgccagatg gctatgatac catcttggat gacaccgtga ccttgtctgt aggacaaaaa
    22561 caactattga ctattgctcg tgcccttctt aaggatgcac cgcttttgat tttggatgag
    22621 gcgacttctt ctgttgacac acggacagag gaattgatcc aaaaagccat ggaccgtttg
    22681 atggaaggac gcacatcctt tgtcattgcc caccgcttgt caaccatccg aaatgcagac
    22741 ttgatcttgg tcatgaaaga tggaaatatc atcgagcaag gcaactatga ggaactgatg
    22801 gtgtaaggtg gcttctacgc tgacttgtac aatagtcaat ttacagaaga tgaagcagaa
    22861 gaataaatca aaagaaggct tgacggcctt ctttttctta tttatactag tacacataga
    22921 aagagagaag tatgagtcag aaattataca atatgaaatt tgctgctgtc tatttagcct
    22981 tgattgcaaa agttgagcga aagggtggag aggcagagtc agttcaccaa gtgaccagtt
    23041 ggttgacagg gtatgaagtg agtgacgttc ttgcttgtct ggatagggat gttacttacg
    23101 gagatttttt tcgacaagca ccatattatg tccctgaacg aattgcaatt acagggaaga
    23161 tttgcggtgt ccgtattgag gaaattgatg atcctctgat gcaggaaata cgtcgcttgg
    23221 acaagctagt ggattggctt gccaagggga aaacatctca acaagttcta gaaaagtatg
    23281 agaagcataa atgaaaaatt atcaagaatg gtatcgaaat atcagctcca gactaactag
    23341 tcgtccaatt cttttattcc tattacgcag tttcaatcgt ttgatgacag tcgccatgcc
    23401 cctggtctat ctgatcttgc tagtcaccac ttacctgcaa ctaggacttg gtcagcaagt
    23461 tggggtttat gtgtttatcc ctgctacagg ttttgtgatt ttatcccttc ttcgcaagaa
    23521 aatcaatgcc cctaggcctt atgaggaatg ggatattaaa cccttgcttg acagagatag
    23581 tcctggtcag tctatgccca gtcgtcatgt cttttcagca accattatct ccatgacttg
    23641 cttacatgct agtctaactg tgggctttat cttgttggtc ttgtcagccc tcctcggtct
    23701 cgtgagagtc ttaggtggtg tacattatcc caaggatgta gtagttggtt atatttgtgg
    23761 tcttgcgtgg ggtgtgcttt tctttctatt ttgacctgta agttaagttg gtcttgcaac
    23821 cacttactgc ttcaaattga ccacttgctt ttttgccctt gtattcctaa cttagctttg
    23881 atatagtaga gtcagaaagg agatgtgatg aagttacgaa ttgagattga cggcaattta
    23941 gaggagactg aaattgtcat caagaccccc actttgacag atgaaattgc agacttgcaa
    24001 cggctcttgc aagagtcaaa ggctccgagg ttgacttttt acaaggggac aggtgaatat
    24061 tatctagacc tgtcagaaat tctcttcttt gaaacagaag ggagcaagat ctacgctcat
    24121 aaccagaagg aagcttatga ggttcgcctc aagctctatg agttggagtc tatcttgcct
    24181 cgctatttta atcgagtttc caagtcaacg atcgcaaaca tccgtcagat ttactcagtg
    24241 gacaagtcct tttcaggaac gggcaccatt tccttttatc agacgcacaa ggaggttcat
    24301 gtctcacggc attaccaatc cctcctaaaa gaaaatctaa gaaacatgag gtaaaaaaca
    24361 tgaaaaagaa agcatttggt attgttttat tggttttagc agcttggatc ttgctgcaag
    24421 ggaattttgg aattccttct ttggatggta aaatatggcc tttactaggt attgtttttt
    24481 ttgcttataa gtccattgag tccatcctta gacgtcatct cacttcggca gtttttacag
    24541 gtttactggc gatcatcatt gcaaattacg cttatgactt gttaccagtt accaatcatt
    24601 ctcttatttg ggctagcatc ttggtggtac ttggtgttgg ttatctgacg cattcaagta
    24661 agttctggaa tgaaaaaaaa tggtggtaca atgggaaaaa aacagtcgtc acggataagg
    24721 aagtcgcttt tggtagcggg accttctata agcaagatca agatctcgta gatgaccaag
    24781 tggaagtcgc ttttggggat gctaaaatct actatgataa tgcagagatg ctaggtgatt
    24841 ttgcaacttt aaatattgaa gtggccttcg gaaatgcaac cgtctatgtt ccacaacact
    24901 ggcgtgtaga tttgaaagta gaaacctcct ttggtgcagc taaggctgac gctcctgtag
    24961 ccccaaccag caaaaccttg attatccgtg gagatgtggc ttttgggaag ttggaaattg
    25021 tctacgttaa ataaaaaaat cttcacttca accatcaaaa tagacgtact aagagtagga
    25081 aattgatgcc ttgctctgat ttcagttcta tggttgttag actttaaaaa atgaaatgct
    25141 gcctttaaaa gttgtatatt tttcgatatt ttggctttta cgtttgatgc atctatgtcc
    25201 tacagcgtag atgatgtagt gtcaaatgct tttaaaaaac gaatgatatt ggacagtttt
    25261 tttgccttta attgctcagg aaccatgaaa gtcagtactt gggtttatga caagggagaa
    25321 tggtattatg taagttcttc tggtgccatg attgcgaatg attgggtcaa agacaatggc
    25381 aagtagtatt atctggcttc atcaggtaag atgcttcgca atacctacac acctgatggt
    25441 tactacgttg gcaacttagg tgcctggcaa taagaataat actctttgaa aatctcttca
    25501 aaccacgtca acgtcgcctt atctacaacc tcaaaaccgt gttttgagca gcctgcggct
    25561 agctttctag tttgctctta gtataagaag tccttttcct taaaggaaga ggctttttac
    25621 ttgcttttct gctgcttcct catttgtcct gaagcctttt ttgtgttaaa atgaatggta
    25681 tgaaagctaa aaaaatgtgg atggcaggct tggctctgct aggtatcgga agccttgctc
    25741 ttgctacgaa aaaagttgca gatgaccgta agctcatgaa gactcaggaa gagttgacag
    25801 agattgtgcg agaccatttt tcagacatgg gggaaattgc gaccctctat gttcaagtct
    25861 atgaaagcag tctagagagc ttgcttggtg gcgtcatttt tgaggatggc cgtcattata
    25921 cctttgtcta tgaaaatgaa gacctagtct atgaggagga agtcttatga tacagccagc
    25981 aagtttagaa gaattagcat ctttagtgga aaaagcgggc aagaaggtct tcctttttgt
    26041 ggcagactgg tgtggcgatt gtcgttatat ttatcctgcc ttaccagaga ttgaagagac
    26101 caatccagag ttcaccttta ttcgaatgga ccgagatcag tatatggatt tggccaaact
    26161 ctgggatgtt tacggaattc ctagccttgt tgttctagaa aaggacaagg aaatcggtcg
    26221 ttttgtcaat cgcgaccgta aaagtaagga gcaaattaac gattttttag caggattgaa
    26281 ataggagaaa aaggaaacaa tgatttttac gtataacaaa gaacatgtcg gtgatgtcct
    26341 tatggtcatc gtgaaaaata gcggagatgc caaactgaat gtggaacgca aaggcaaggt
    26401 agcccgtgtt ttcctcaaag aaaatgggga aacagtagct tggaacattt ttgaggtttc
    26461 gagcttgttt gaaattgcag agcgcggtca agtcttttta tcagatgagc aagtcgctcg
    26521 tttgaaccaa gaattacagg cggaaggttt tacagaagaa attgttaatg ataaggaacc
    26581 taagtttgtt gttggtgaaa ttgtcgagat ggtagctcat ccagacagtg accacctcaa
    26641 catctgccaa gttgcagtcg caagtgacaa gatagtgcaa atcgttgcag gagcacctaa
    26701 tgcgcgtgtt gggttgaaaa ccattgtggc tcttcctggt gccatgatgc caaaagggaa
    26761 tttcattttc ccaggcgaac ttcgtggtga aaagagtttt gggatgatgt gtagtcctcg
    26821 tgaattgcat ttgccaaatg ctccgcaaaa acgtggggtg cttgaattat cagaagacca
    26881 agttgtcgga acaccgttcg acccagcgaa acactggact gcctaggaac ttgtcagcat
    26941 ctgatagaag gaaataagat ggcaaaaaat gtagtgatta cgggagcaac ctcaggaatc
    27001 ggtgaagcga ttgcgcgtgc ttatctggag cagggtgagg atgtcgttct aacaggacga
    27061 cggatagaca gattagaaat cctcaagtcg gagtttgcag taagctttcc aaatcaaacc
    27121 gtctggactt ttccactaga tgtgacggat atggtcatgg tgaagactgt ttgctctgat
    27181 attctagaaa cgatagggag gattgatatc ttggtcaaca acgccggact ggctcttgac
    27241 ttggctccct atcaagacta tgaggagttg gatatgttga ccatgttgga taccaatgtt
    27301 aaaggtctga tggcggttac tcgctgtttc ttgccagcaa tgataaaagt caatcaaggt
    27361 catattatca atatggggtc aaccgcagga atctacgcct atgctggtgc cgctgtttac
    27421 tcagctacca aggctgcggt taagaccttt tcggatggac tgcgaattga taccatcgca
    27481 acggatatca aggtgacaac cattcagcct gggattgtcg aaacagattt ctcaactgtt
    27541 cgttttcatg gtgataaaga gcgggctgcg tccgtttacc aaggaataga agccttgcaa
    27601 gctcaggata ttgcagacac agtagtctat gtgaccagtc agcctcgccg tgttcagatt
    27661 acagatatga ccattatggc caatcaacag gcgacaggtt tcatgattca taaaaaataa
    27721 gaaatttcct cgaaaagtta caaatttctg taactttttt tgatttccta cgaatagata
    27781 agtaggagga agaaaatatg tataataaag ttatcttgat tgggcgttta acgtctacac
    27841 cagaattgca caaaaccaac aatgacaagt cggtagcgcg agcaactatc gctgtcaacc
    27901 gtcgttacaa agaccaaaac ggtgaacgtg aagctgattt tgtcaatatg gtcctatggg
    27961 gcaggctagc agaaactttg gcaagctacg caaccaaagg tagtctcatt tccgttgatg
    28021 gagaattgcg tacccgtcgc tttgagaaaa atggtcagat gaactatgta accgaagtcc
    28081 ttgtgacagg attccaactc ttagaaagtc gtgctcaacg tgccatgcgt gaaaataatg
    28141 caggccaaga tttggcagat ttggtcttgg aagaggaaga attgccattt taatactctt
    28201 cgaaaatctc ttcaaaccac gttagcttta tccacaacat caaagcaatg ctttgagcag
    28261 cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaaca ttaaaaagtc
    28321 tgagttggtc tcaggctttt tatcttgaga aagtcagact tttttcttga ctatttctga
    28381 ccaagtgata caatagaatt atgaattagc actcaagttc aaagagtgct aataatatct
    28441 atctcattat ggaggaaatc agatgttgaa accattaggg gaccgtgtgg tcttaaaaat
    28501 agaagaaaaa gaacaaaccg ttgggggctt tgtccttgca ggctcagccc aagaaaaaac
    28561 caaaacagct caagttgtgg ctactggaca aggtgttcgt accttgaacg gtgacttggt
    28621 tgctccaagt gttaaaactg gagatcgtgt cttagttgaa gcccacgcag gtcttgatgt
    28681 caaagatggc gatgaaaagt acatcatcgt aggcgaagct aacatcttgg caatcattga
    28741 ggaatagaag gagaaagtaa gtatgtcaaa agaaattaaa ttttcatcag atgcccgttc
    28801 agccatggtt cgtggtgtcg atatccttgc agacactgtt aaagtaacct tgggaccaaa
    28861 aggtcgcaat gtcgttcttg aaaagtcatt cggttcaccc ttgattacca atgacggtgt
    28921 gaccattgcc aaagaaatcg aattggaaga ccattttgaa aatatgggtg ctaagttagt
    28981 atcagaagta gcttctaaaa ccaatgatat cgcaggtgac ggaactacga ctgcaacagt
    29041 cttgacccaa gctatcgtcc gtgaaggaat caaaaacgtc acagcaggtg caaatccaat
    29101 cggtattcgt cgtgggattg aaacagcagt tgccgcagca gttgaagctt tgaaaaacaa
    29161 cgccatccct gttgccaata aagaagctat cgctcaagtt gcagccgtat cttctcgttc
    29221 tgaaaaagtt ggtgagtaca tctctgaagc aatggaaaaa gttggcaaag acggtgtcat
    29281 caccatcgaa gagtcacgtg gtatggaaac agagcttgaa gtcgtagaag gaatgcagtt
    29341 tgaccgtggt tacctttcac agtacatggt gacagatagc gaaaaaatgg tggctgacct
    29401 tgaaaatccg tacattttga ttacagacaa gaaaatttcc aatatccaag aaatcttgcc
    29461 acttttggaa agcattctcc aaagcaatcg tccactcttg attattgcgg atgatgtgga
    29521 tggcgaggct cttccaactc ttgttttgaa caagattcgt ggaaccttca acgtagtagc
    29581 agtcaaggca cctggttttg gtgaccgtcg caaagctatg cttgaagata tcgccatctt
    29641 aacaggcgga acagttatca cagaagacct tggtcttgag ttgaaagatg cgacaattga
    29701 agctcttggt caagcagcga gagtgaccgt ggacaaagat agcacggtta ttgtagaagg
    29761 tgcaggaaat cctgaagcga tttctcaccg tgttgcggtt atcaagtctc aaatcgaaac
    29821 tacaacttct gaatttgacc gtgaaaaatt gcaagaacgc ttggccaaat tgtcaggtgg
    29881 tgtagcggtt attaaggtcg gagccgcaac tgaaactgag ttgaaagaaa tgaaactccg
    29941 cattgaagat gccctcaacg ctactcgtgc agctgttgaa gaaggtattg ttgcaggtgg
    30001 tggaacagct cttgccaatg tgattccagc tgttgctacc ttggaattga caggagatga
    30061 agcaacagga cgtaatattg ttctccgtgc tttggaagaa cctgttcgtc aaattgctca
    30121 caatgcagga tttgaaggat ctatcgttat cgatcgtttg aaaaatgctg agcttggtat
    30181 aggattcaac gcagcaactg gcgagtgggt taacatgatt gatcaaggta tcattgatcc
    30241 agttaaagtg agtcgttcag ccctacaaaa tgcagcatct gtagccagct tgattttgac
    30301 aacagaagca gtcgtagcca ataaaccaga accagtagcc ccagctccag caatggatcc
    30361 aagcatgatg ggcgggatga tgtaagcttt ctatagaaaa caacttataa aaaacacaaa
    30421 aggagggaat gactaaccct tctttttata atattcactt ctaaattgat ttgagctctc
    30481 ctaacttata tgataaaata agactagaaa aaggagaaga acatgatcga tgtagaagaa
    30541 attctgtgca agatgccccc caatcagaag attaattatg accgtgtcat gcagaaaatg
    30601 gtacaagcat gggagaaaaa tgagcagcgg ccaaccattc tcgtgcatgt ttgctgtgcc
    30661 ccttgtagta cctatacact agaatatttg accaagtatg cagatgtgac catctatttt
    30721 gccaattcta atatccatcc caaggtagaa taccataagc gggtctatgt catcaagaaa
    30781 tttgttagtg attttaatga gcggacagga aatacggttc agtacctaga agctccctac
    30841 gaacccaatt aataccgaaa actagttagg ggactagagg aggagcccga aggtggcgac
    30901 cgttgcaagg tttgttttga ctaccgactg gataaaacag cgcaagtggc tatggacttg
    30961 ggctttgact actttggttc agccttgacc atcagtcctc ataagaattc tcaaaccatc
    31021 aacagcatcg gaatcgatgt gcaaaaaatt tacacgaccc actatcttcc caacgatttc
    31081 aagaaaaatc aaggctacaa acgttcagta gagatgtgtg aggagtatga tatctatcgt
    31141 caatgttatt gtggctgcgt ctatgcagcc caagcccaga atattgacct ggttcaagtt
    31201 aagaaggacg ctacagcatt cttgttgggt aaggatgttg agaaagacta ttctcatatc
    31261 aaatttatag tagattgaaa ctagaatagt acacctttac ttctaaaaca ttgttagaaa
    31321 tcgatttgac tgtccttatt tcattttact atactattac gaaattagat atataaatga
    31381 aaacttgcct caaggtagtt ttttttgcta gtagaaaagc gatagacaga aattgttgga
    31441 ctcttaaaaa aatgaagttt tgctcaaaag agcttcttaa attaaaacga gcaattatca
    31501 gttcaaatct gtttcaaaag aagaacggat aaattaatcg atgctttgtt tttgagttag
    31561 gaagttaagc atgccaaact gagtcgtagg aataaatttc tttatagaaa tgtgttacaa
    31621 ctctgctata acggaatatt ccttttttgc atttatacaa cttatttaac actatcttta
    31681 ttcttgtgat ataatgccaa attatagagt ggaggtcatt taaaatgatt gataaagtaa
    31741 ttgaacaata taaaagtcat gataatcttg atattcgagt agaattgcat aagaagtatt
    31801 caaaaaataa attgggattt aataattgga tattttctaa ctaccaaatc actgatgaag
    31861 taaaggttct agaattggga tgtggtacag gagaattgtg gaaaagtaat agtgattcta
    31921 tagataaaat gaagcagttg attgttacag atttttctaa agatatggta aaatcaacga
    31981 agtcagtgat tggaaataga aacaatgtca attatgagat aatggatatt caaaagattt
    32041 cttttgagaa tgaaactttt gatattgtta ttgctaatat gcttctacat catgtgaatg
    32101 atattcctaa agctctctct gaggtgaata gggtcttaaa aaccggagga attttttact
    32161 gtgctacatt tggtgaaaat ggagttgtaa attatttggc aaatttattt aaagatgagg
    32221 ttaatcaaga tttagaaaat agaacgttta ctttacaaaa tggtaaaagg tacctgagta
    32281 ggtattttaa ctctgtcgat acattactct atgatgatga gttacaggta actagtatag
    32341 atgacctagt taaatacatc caatcgttta aaggaatttc agaaataggt tcactagaag
    32401 aggaaataat acgtaaaaga ttggaaagtg agtttaataa tggtatgttg atcattccta
    32461 aagaatatgg tatgtttatc gctcgaaaag aaagttaagg gaatgaaagt gtgaaaaatt
    32521 acggagaagc ttttcgatat tttagaaaat taaacggata ttctttagag tatgctgcag
    32581 ctgattctat atcaaaatct caactttcta gatttgaaag gggagaaaat gaaatttctc
    32641 tttcaacatt ttttgaatta ttatcaaata tcaatgtttc gatagagaat ttttgtaatc
    32701 acttagaaca ttataaaaga tcggagcgtg atgatttttt ggttaattta tctccaaatt
    32761 tttatagttt gaatattaaa ggattggagg taataaaaaa taagcaacaa aaactttttg
    32821 agaagagtgg gaaaaactca taaaataaat acaattatgg ttcagggatt atgaaatcag
    32881 ctagattgta atcatgtagt tagtagagat gatctaaatt tagtatatga ctatttattc
    32941 cagaaggaac gatggaagtc ctatgagata acgctgattg gtaatttata tcatcttttt
    33001 gaaatagatt atatttacat ggtcggaaaa gaaatactag agcgtacaca ttattacgaa
    33061 aaaatcggca agaatagaca tttagttgtg tcagcttgtt taaatttttg gttctgttgc
    33121 cttgaaaatt cacatctaat atatgcagac tactttgaaa tgaaattaca aaaattatta
    33181 aaagatgaca caaaagtttt tgaaaaatct acattcaaat ttgtagaagg atataaaata
    33241 tacctgacag aatctaaaga atctggaatt aaacaaatgg acaatgtcat aaaatatttt
    33301 gagtttattg aatctaaaag tattgcttta tattttcaaa aacgattaaa tgagctgata
    33361 gattaaatat cattttctct gttaagatat tgtttttaaa atattgtact aaatgattga
    33421 tgctatgtgg aaatacaaaa aaatgttttt gatacgaagt tgacctgtat tttttatact
    33481 aatcattttc gtattttttg tattaaacga tataagtttg ttgtaaactt actaggaata
    33541 aagacattaa aaaataatag tatatctatt tgttttatat attttacgaa ttctgcataa
    33601 atctctttct agtaatgtgt tgtaactctg ctataatgga tttattcctt tttgtgttta
    33661 cacaatttat tttatactac caaaaaaaca aggtcaggat tttgttcctg acctttgaca
    33721 actttaccga ttctttagtt ctacatagcg cttgtaccaa atgtttacat aggcttctga
    33781 gaaaggacca cgtccattgt taatccaatc aacaagaatt ttgacatgtt cttttaaaat
    33841 atagtccaag tcatcagaat aattcatttt gcgtttgtga cgctcgtatt cttcaacgtc
    33901 caagagacgt ttttccccat ctgtaaaaat tttaacatcc aaatcgtaat caatatactt
    33961 cagtgcttct tcatccagat agtaggggct agccatattg caatagtaag aagttccatt
    34021 atcacgaatc atggcaatga tattaaacca atatttcttg tgaaagtaaa caatagccgg
    34081 ttctcgagtg acccaacgac gaccatcact ttcggtaaca agtgtatgat cgttgacacc
    34141 aataatggcg ttttctgttg tttttagtac catggtgtcc cgccaagttc ggtggagact
    34201 cccatcatgc ttataacttt gaattgtaat aaagtcgcct tcttttggaa gcttcataac
    34261 taaccaactt tctacaattt ataagtttat catttactat tgtaccataa aattacctaa
    34321 aatctgtgaa tttcacttgg aaatattaaa gatattctct aagagcgctt gctatatccg
    34381 aaaaatcgta gccctttcgt gctaaaactt gagttaaacg ctgcttcagt tcgtatcctt
    34441 catactttcg ggcatactta gtatattgct tatcaagttc cttgaagatg agttcctgag
    34501 tcgtttcttg gtcaacttga ctatccaatt cgtcaaaggc aattttagca tcaaaataag
    34561 agaagccctt gttagtcaag ttctggataa tcttatcttg cagggcacga gctggaagtt
    34621 ttccctcata ttttttcaat agtttattgg ctacacgttg agcaacttcc gaaaaatcaa
    34681 aatcattcaa gatttcttct atagtagatt ttgaaattcc tttttgtgct aatttctgag
    34741 tcagtacata aggtcccttg tctcctgaaa cttgattggc attgatgata gcataagcgt
    34801 actgaccatc attaatccac ttatcttctt taagattagc aataacttga gaaacgatgt
    34861 ttttatcaat atcgtatttt ttcagatatt ctctgacttc tttttcagtg cgtgctttaa
    34921 aggataagtg gtagagggcc agattcttac cataagaaaa ttgagcaaag tcttgaatct
    34981 ctttcaattc ctcttcgctt atcaccttat ctctcgataa cataaaacga acaattgtat
    35041 cttcggtgat atagcatttg tcgccattat caagctccat cagatagagt ctttttttct
    35101 tttcaagttt tgtgattttc atagctctat tataactcaa aatgtgataa gataggggta
    35161 tgaatctgaa agtgaaacaa aaaataccat taaaaatcaa gcgcatggga attaacggtg
    35221 agggaatcgg cttttaccaa aaaacattag tctttgtacc tggagctctc aaaggcgaag
    35281 atatctattg tcagattact tctattagac gcaactttgt tgaagcaaaa ttactgaagg
    35341 tcaacaagaa gtctaaattt cgaattgtgc catcttgtac tatttataat gaatgcggag
    35401 gctgccaaat catgcacctg cattatgata agcagctgga gttcaagacg gacttacttc
    35461 atcaagcgct gaaaaaattt gctcctgcag gatatgaaaa ttatgaaatt cgtccaacta
    35521 ttggaatgca ggaaccaaaa tattacagag ctaagttaca atttcagact cgaaaattta
    35581 aaaatcaggt caaggcgggc ttatatgcac aaaactctca ctatttagta gagttgaaag
    35641 actgcctggt acaagataag gaaacccaag tgattgctaa tcgcttagca gaattactta
    35701 cttatcacca gattccaatc acggatgaga gaaaagttct aggtgtccgt actattatgg
    35761 tccgacgcgc gagaaagacc ggacaggttc agattattat tgttacaaac cgccagctta
    35821 atttaactca attggtaaaa gagttggtta aagatttccc agaagttgtg acagtagctg
    35881 ttaatacaaa tacagctaaa accagtgaga tatatggtga aaagacagag attatctggg
    35941 ggcaagagag tattcaagaa ggtgtactca attatgaatt ttcactatcc cctcgagctt
    36001 tttatcaact aaatcctgag caaacagaag tcctctatag cgaagcagta aaagcgctgg
    36061 atgttgataa agaagaccat ttgattgacg cttattgtgg agttggaacg attggatttg
    36121 cctttgcaaa gaaagtaaaa acactcagag gtatggatat tattccagaa gctattgaag
    36181 atgccaagcg aaatgctaaa agaatgggat ttgacaatac tcattatgaa gctggaacgg
    36241 cagaagagat tattcctcgt tggtacaagg aaggctaccg agcagatgct ttgattgttg
    36301 acccaccacg tacaggtctg gatgataagt tattagatac tattcttact tatgtaccag
    36361 aaaaaatggt ttatatttct tgtaatgttt cgaccttggc tcgtgatttg gtacgcttag
    36421 tagaagtcta tgatcttcat tatatccagt cggtcgatat gttcccacat acagctcgaa
    36481 ctgaagctgt tgtaaaatta ataaaaaaag ttt
//
LOCUS       DBEJKC010000015        35716 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.015, whole genome shotgun sequence.
ACCESSION   DBEJKC010000015 DBEJKC010000000
VERSION     DBEJKC010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 35716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35716
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.015"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            480..1523
                     /locus_tag="ACL3G6_000766"
     CDS             480..1523
                     /locus_tag="ACL3G6_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HGR0545332.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            1690..3777
                     /gene="topA"
                     /locus_tag="ACL3G6_000767"
     CDS             1690..3777
                     /gene="topA"
                     /locus_tag="ACL3G6_000767"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HGR0545333.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMAVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            3883..4242
                     /locus_tag="ACL3G6_000768"
     CDS             3883..4242
                     /locus_tag="ACL3G6_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HGR0545334.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4335..4967
                     /locus_tag="ACL3G6_000769"
     CDS             4335..4967
                     /locus_tag="ACL3G6_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HGR0545335.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGTLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            5011..5667
                     /locus_tag="ACL3G6_000770"
     CDS             5011..5667
                     /locus_tag="ACL3G6_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HGR0545336.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5737..6780
                     /locus_tag="ACL3G6_000771"
                     /pseudo
     CDS             5737..6780
                     /locus_tag="ACL3G6_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261078.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-isopropylmalate synthase regulatory
                     domain-containing protein"
     gene            6792..7818
                     /gene="leuB"
                     /locus_tag="ACL3G6_000772"
                     /pseudo
     CDS             6792..7818
                     /gene="leuB"
                     /locus_tag="ACL3G6_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            7815..8084
                     /locus_tag="ACL3G6_000773"
     CDS             7815..8084
                     /locus_tag="ACL3G6_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HGR0545337.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            8088..8447
                     /gene="leuD"
                     /locus_tag="ACL3G6_000774"
     CDS             8088..8447
                     /gene="leuD"
                     /locus_tag="ACL3G6_000774"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HGR0545338.1"
                     /translation="MVGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSKWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8609..9232
                     /locus_tag="ACL3G6_000775"
                     /pseudo
     CDS             8609..9232
                     /locus_tag="ACL3G6_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Sua5/YciO/YrdC/YwlC family protein"
     gene            9398..11329
                     /locus_tag="ACL3G6_000776"
     CDS             9398..11329
                     /locus_tag="ACL3G6_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HGR0545339.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            11316..12632
                     /locus_tag="ACL3G6_000777"
     CDS             11316..12632
                     /locus_tag="ACL3G6_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HGR0545340.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYQRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            12807..13793
                     /locus_tag="ACL3G6_000778"
     CDS             12807..13793
                     /locus_tag="ACL3G6_000778"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HGR0545341.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHNQGLIASISVGVKDYEY
                     DFVSQLKADTPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            13857..13928
                     /locus_tag="ACL3G6_000779"
     tRNA            13857..13928
                     /locus_tag="ACL3G6_000779"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13890..13892,aa:Arg,seq:ccg)
     gene            14111..14809
                     /gene="rnc"
                     /locus_tag="ACL3G6_000780"
     CDS             14111..14809
                     /gene="rnc"
                     /locus_tag="ACL3G6_000780"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HGR0545342.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            14800..18339
                     /gene="smc"
                     /locus_tag="ACL3G6_000781"
     CDS             14800..18339
                     /gene="smc"
                     /locus_tag="ACL3G6_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HGR0545343.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENACKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDENAATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIVIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMAALTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQESLATIASEKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEEVAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            18336..19130
                     /locus_tag="ACL3G6_000782"
     CDS             18336..19130
                     /locus_tag="ACL3G6_000782"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0545344.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            19130..19948
                     /locus_tag="ACL3G6_000783"
     CDS             19130..19948
                     /locus_tag="ACL3G6_000783"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0545345.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVSEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            19952..21229
                     /gene="ftsY"
                     /locus_tag="ACL3G6_000784"
     CDS             19952..21229
                     /gene="ftsY"
                     /locus_tag="ACL3G6_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HGR0545346.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETIE
                     ENNSEVLEAERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(21273..22760)
                     /gene="zwf"
                     /locus_tag="ACL3G6_000785"
     CDS             complement(21273..22760)
                     /gene="zwf"
                     /locus_tag="ACL3G6_000785"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HGR0545347.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATANKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFDAKWTWQPDIAYRQDGRFE"
     gene            complement(22909..23649)
                     /locus_tag="ACL3G6_000786"
     CDS             complement(22909..23649)
                     /locus_tag="ACL3G6_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0545348.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(23649..25814)
                     /locus_tag="ACL3G6_000787"
     CDS             complement(23649..25814)
                     /locus_tag="ACL3G6_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGR0545349.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            25987..26940
                     /locus_tag="ACL3G6_000788"
     CDS             25987..26940
                     /locus_tag="ACL3G6_000788"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HGR0545350.1"
                     /translation="MKNKRIFKDFQASKMNLNIYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            27017..29005
                     /gene="uvrB"
                     /locus_tag="ACL3G6_000789"
     CDS             27017..29005
                     /gene="uvrB"
                     /locus_tag="ACL3G6_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HGR0545351.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            29015..29578
                     /locus_tag="ACL3G6_000790"
     CDS             29015..29578
                     /locus_tag="ACL3G6_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR0545352.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKMNDGYYQINGNS"
     gene            29544..30053
                     /locus_tag="ACL3G6_000791"
     CDS             29544..30053
                     /locus_tag="ACL3G6_000791"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0545353.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIGDLKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SKIILKSRS"
     gene            30106..30573
                     /locus_tag="ACL3G6_000792"
     CDS             30106..30573
                     /locus_tag="ACL3G6_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGR0545354.1"
                     /translation="MSRSQLTILTNICLIEDLETQCVVMQYRAPETNRWSGYAFPGGH
                     VENGEAFAESVIREIYEETGLTIQNPQLVGVKNWPLDTGGRYIVFCYKATEFTGTLQS
                     SDEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(30570..31085)
                     /locus_tag="ACL3G6_000793"
     CDS             complement(30570..31085)
                     /locus_tag="ACL3G6_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HGR0545355.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHQVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(31097..31624)
                     /locus_tag="ACL3G6_000794"
     CDS             complement(31097..31624)
                     /locus_tag="ACL3G6_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0545356.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(31906..32469)
                     /locus_tag="ACL3G6_000795"
     CDS             complement(31906..32469)
                     /locus_tag="ACL3G6_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0545357.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(32453..33004)
                     /gene="coaC"
                     /locus_tag="ACL3G6_000796"
     CDS             complement(32453..33004)
                     /gene="coaC"
                     /locus_tag="ACL3G6_000796"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HGR0545358.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETLDEKTL"
     gene            complement(33016..33705)
                     /gene="coaB"
                     /locus_tag="ACL3G6_000797"
     CDS             complement(33016..33705)
                     /gene="coaB"
                     /locus_tag="ACL3G6_000797"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HGR0545359.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLFAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            33935..35605
                     /locus_tag="ACL3G6_000798"
     CDS             33935..35605
                     /locus_tag="ACL3G6_000798"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HGR0545360.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
BASE COUNT        11029 a         6333 c         7929 g        10425 t
ORIGIN      
        1 actgttatag attcaataca ctataattta gtgtaattga gaaaggagaa atgattgtga
       61 ttgatgttgg ctaggttatg ttcaatgatt cctaccgtct caaatcttgt cagtaaggaa
      121 aaataaattc ttcaaaagta gagattacaa ggcttgttta agaaagaatt caaagacctt
      181 gacaaataaa aataaaatgg ttattataag aaatggtcta aaatagatga tgatactttt
      241 cgaaaatctt tttacgtcag ctcagctttg ccttgctgtg ttttgagcaa gctacggtta
      301 gcttccgagt ttgattttca tttactagaa atgaaactga tgagagatat cagtagacat
      361 ttgagtcagg atattatgga aaatgataaa aagagctcgt gagattggca tatcagacta
      421 ctaaagtatt gagtttgtta ggattttagc gactagttag ctgggaaagg aagatatttg
      481 tgacaaataa taaactgtat tcgttgatag aatttagaaa taaaatatat gaagaattag
      541 aactttccag aagtgattta gcgattttac tatgtgccat gcttatcgcc tctatcggat
      601 taaatatgga ttcgactccc gtgattattg gagccatgtt aatctctcct ttgatgacac
      661 ctattctggg agtggggctc tctctagcta tatttgattt taaattgtta agaaaatctt
      721 ttaaaatatt agctattcaa attcttgcca gtctaatagc ttcaacactt tatttttatc
      781 tttctcccat ttcgtatgct agttcggaga ttgttgctag aacctctccg actatttggg
      841 atgttctcat tgcttttgta ggagggatag caggtattat tggtgctagg aaaaaagaga
      901 ccaataatat tgttcctggt gttgctattg caaccgcctt gatgcctcct ctttgtacag
      961 taggttatgc tattgcttct gctaatctaa aatttatcat aggctcctct tacctattcc
     1021 tcatcaattg tagctttatt gtcattgcga cttatatagg tgttaggttg atgatggtta
     1081 agaaacatta ttttaaagat aacgaagaag actctaaaat gcgtaggatt ttgcttctag
     1141 ttgctgtttt gctgatgatt ccgagtttca tctctgcaac gactttagtg agagaaacgt
     1201 tgaaaaaaga gtcccttaag aaatttatat cagagcagtt tcaggggtat aatattttga
     1261 aaaaaaccta ttctaaaaag actcataccc taaagctaac catttcagga aattatttga
     1321 cagaagaaga actcgatatg atttcaagta agagaggtga ctatggttta agtgatgttt
     1381 ctgttcaagt ttcacaattg tctgattcag aacaacttag taaggaagag ctggtggagt
     1441 atttcttcca gtatatcaag gataaggaag caaaagaaaa ggagaaagcc aataaatttg
     1501 atacagagtc tgaggagcaa taatttcttg agaatagctg gtttctctcg tgagtcttct
     1561 atgtatatca aaggaagact gaggttttaa gtataaaact tttcttctat tatagtagct
     1621 aagtcttgac agggttcaaa aaatggttta cactttataa agtttattac tttgaaaagg
     1681 tgtgatactg tggctacggc aacaaaaaag aaaaaatcaa cagttaaaaa aaatctagtc
     1741 atcgtggagt cgcctgctaa ggccaagacg attgaaaaat atctaggcag aaactacaag
     1801 gttttagcca gtgtcgggca tatccgtgat ttgaagaaat ccagtatgtc cgtcgatatt
     1861 gaaaataatt atgaaccgca atatatcaat atccgaggaa aaggccctct tatcaatgac
     1921 ttgaaaaaag aagctaaaaa agctaataaa gtttttctcg cgagtgaccc ggaccgtgaa
     1981 ggagaagcga tttcttggca tttggcccat attctcaact tggatgaaaa tgatgccaac
     2041 cgtgtggtct tcaatgaaat caccaaggat gcagtcaaaa atgcttttaa agaacctcgt
     2101 aagatcgata tggacttggt cgatgcccaa caagctcgtc ggatcttgga tcgcttggta
     2161 gggtattcga tttcgcctat tttgtggaag aaggtcaaga agggcttgtc agcaggtcgc
     2221 gttcagtcca ttgcccttaa actcatcatt gaccgtgaaa atgaaatcaa tgccttccag
     2281 ccagaagaat actggacagt tgatgctgtc tttaaaaagg gaaccaaaca atttcatgct
     2341 tccttctatg gagtagatgg taaaaagatg aaactgacca gcaataacga agtcaaggaa
     2401 gtcttgtctc gtctgacgag taaagacttt tcagtagatc aggtggataa gaaagagcgt
     2461 aagcgcaatg ctcctttacc ctataccact tcatctatgc agatggatgc tgccaataaa
     2521 atcaatttcc gtactcgaaa aaccatgatg gttgcccaac agctctatga aggaattaat
     2581 atcggttctg gtgttcaagg tttgattacc tatatgcgta ccgattcgac tcgtatcagt
     2641 cctgtagcgc aaaatgaggc ggcaagcttc attacggatc gttttggtag caagtattct
     2701 aagcacggta gcaaggtcaa aaacgcatca ggtgctcagg atgcccatga ggctattcgt
     2761 ccgtcgagtg tctttaatac accagaaagc atcgctaagt atctggacaa ggatcagctc
     2821 aagctatata cccttatctg gaatcgtttt gtggctagcc agatgacagc ggccgttttt
     2881 gataccatgg ctgttaaatt gtctcaaaat ggagttcaat ttgctgccaa tggtagtcag
     2941 gttaagtttg atggttatct tgccatttat aatgattctg acaagaataa aatgctacca
     3001 gatatggctg ttggagatgt ggtcaaacag gttaatagca aaccagagca acatttcacc
     3061 caaccgcctg cccgttattc tgaagcaaca ctgattaaaa ccttagagga aaatggggtt
     3121 ggacgtccat caacctatgc gccaaccatt gaaaccattc agaaacgtta ttatgttcgc
     3181 ctggcagcca aacgttttga accgacagag ttgggagaaa ttgtcaataa gctcatcgtt
     3241 gaatatttcc cagatatcgt aaacgtgacc ttcacagctg aaatggaagg taaactggat
     3301 gatgtcgaag ttggaaaaga gcagtggcga cgggtcattg atgcctttta caaaccattc
     3361 tctaaagaag ttgccaaggc tgaagaagaa atggaaaaaa tccagattaa ggatgaacca
     3421 gctggatttg actgtgaagt gtgtggcagt ccaatggtca ttaaacttgg tcgttttggt
     3481 aaattctacg cttgtagcaa tttcccagat tgccgtcata cccaagcaat cgtgaaagag
     3541 attggtgttg agtgtccaag ctgtcatcag ggacaaatta ttgagcgaaa aaccaagcgt
     3601 aatcgccttt tctatggttg caatcgctat ccagaatgtg aatttacctc ttgggacaag
     3661 cctgttggtc gtgactgtcc aaaatgtggc aacttcctca tggagaaaaa agtccgtggt
     3721 ggtggcaagc aggttgtttg tagcaaaggc gactacgagg aagaaaagat taaataagag
     3781 gaggggcccg aaagtaaatt tcaggctcct tttggttaga acttgacaaa atacatcatt
     3841 ttatgcgaaa ctagaagaag attattttaa ctaggagaag ttatgcgtct tatctatctg
     3901 ataattggtt ttttatcact ggccttggct attgttgggg ttgttttacc cttgttgccg
     3961 acaacgcctt tccttttgtt gtctattgct tgtttctcca gaagttccaa gcgtttcgaa
     4021 gactggcttt atcataccaa gctctatcaa acatatgtag ctgattttcg cgagactaag
     4081 tctattacgc gtgaacgaaa gaaaaaaatc atcgtctcta tctacgtctt gatgggaatt
     4141 tctatttatt ttgcacctct tttaccagtc aaaatcggtc tgggtgcttt gaccatcttt
     4201 atcacttatt atcttttcaa ggtcattcca gacaaagaat agttaaaaca gtagttattt
     4261 gccttgataa aattgaaagc atattcataa taatatgata taataaattt gaagtaatat
     4321 tcaaggagaa tcaaatgatt tacgaatttt gtgctgaaaa tgtgacttta cttgaaaaag
     4381 cgatgcaggc tggagctcgt cggattgaac tctgtgataa tctagcagtt ggtgggacaa
     4441 cacccagcta tggagtgact aaggcagcgg ttgaactggc agctaactac gatacaacca
     4501 tcatgaccat gattcggcca cgtggtggtg actttgtcta taatgaccta gaaattgcta
     4561 tcatgctaga agacattcgt ttgactgctc aggctggaag tcaaggggtt gtatttggaa
     4621 ctttaactgc tgataaaaag ttggataagc ctaatctgga aaagttaatt gctgcatcaa
     4681 aaggaatgga aattgtcttt cacatggcct ttgatgaact aagtgatgaa gatcaaccgg
     4741 aagctattga ctggctcagt caagccggtg tcactcgtat cctaactcgt gctggtgtgt
     4801 ctggcgactc cttagaaaaa cgttttgttc actatcacag aattttggag tacgctaaag
     4861 gtaaaattga aattctacca ggtgggggga ttgaccttga aaaccgtcaa acctttatcg
     4921 accaggtggg ggtaacacaa ttgcatggta ctaaggttgt tttttaaaaa atagaaagga
     4981 actgctagct ttgggtagca gttttcactt atgtttgaaa tttttaaatc ctatcaattt
     5041 aatcaagaaa aggctcatga ttatggtttt atagaaaata gcgaagtctg gacatatagt
     5101 tgccagattt tgcaaggtga ctttgtcatg actgtgtcca tcactgctga taatgtgaac
     5161 tttcaagtct ttgaccaaga gactggtgac ctctatcctc acgttcatat ggaaagcatg
     5221 aggggaagtt ttgtcggaaa tgtccgtgag gcttgtctgg agattcttta ccagattcgg
     5281 aaggcttgtt ttgatgtgca agattttatc tgtcatcaga ctaagcgtat catgactcaa
     5341 gttcaggaaa agtatggaaa ccagttggag tatctgtggg aaaaatcgcc tgatacagct
     5401 gtattgcgcc atgaaggcaa tcaaaagtgg tatgccgtct tgatgaaaat ctcttggaat
     5461 aagctggaaa agggcagaga aggacaagtg gaagcagtca acctcaagca tgaccaagta
     5521 gctaatttgc tttcacaaaa ggggatttat ccagccttcc atatgagcaa gcgctactgg
     5581 attagtgtgt cccttgatga tactttatca gatgaagaag tactggaatt gatagaaaaa
     5641 agttggaact taacctctaa aaaatgaaat attttaataa ttttcatgaa ctttcaatta
     5701 gctaaatatt ctttactgaa gaaattttca gaaaatatag gatttaccac accagaggaa
     5761 tatggtgcca tcttcaaata cctgattgag aatgtcaaga cggatcgtca gatcatctat
     5821 tcgcctcact gtcatgatga cctcggaata gcagtggcaa atagccttgc tgctgtcaag
     5881 aatggtgcag gacgtgttga agagactatc aatggtatta gggagcgagc tggaaatgct
     5941 gctttggaag aaattgcagt ggctctcaat attcgccaag attactacca agtagaaacc
     6001 agtattgtcc taactgagac catcaatacg tcagaaatgg tttctcgctt ctctggtatt
     6061 ccagttccta aaaacaaagc cgtcgttggt ggcaatacct tctcccacga atctggtatt
     6121 caccaagatg gagtccttaa aaatcctctc acttatgaga tcatcacacc tgaattggtt
     6181 ggtgttaaga ttccgcttgg aaaattatct ggtcgccatg cttttgttga gaaactgaga
     6241 gaattggccc tagattttac agaagaggat atcaaaccac tctttgctaa gttcaaggca
     6301 ctggtcgata agaagcaaga aatcacagat gcagatattc gagctttggt agctggaacc
     6361 atggttgaaa atccagaagg cttccacttt gatgatttac aacttcaaac tcatgcagat
     6421 aatgacattg aagcgctcgt tagcctagcc aatatggatg gtgagaaagt cgaatttaat
     6481 gcgacagggc aaggttccgt tgaagcaatc tttaatgcta tcgataagtt ctttaaccaa
     6541 tctgttcgtt tggtgtccta cactatcgat gcggtaacag atggaatcga tacccaggaa
     6601 cgggttttgg tcactgttga aaacagagat acagaaacca tcttgaatgc agcagggctt
     6661 gattttgatg tgttgaaggc ttctgctatt gcctatataa acgctaatac ctttgttcaa
     6721 aaagagaatg caggtgagat gggacgcagt gtttcttacc acgatatgcc tagtgtgtaa
     6781 aggagaaggc tatggcaaag aaaatagtag ctctagcagg agacggaatt ggcccagaaa
     6841 tcatggaggc tggtttagaa gttctggagg ctctagctga aaaaacaggt tttgactatg
     6901 agatcgttcg gaggtgcaga tattgatgca gcaggatctc ccttacctga tgaaaccctt
     6961 aaggcaagta gggaagcaga tgctatccta ctagtagcta tcggtagtcc tcagtatgat
     7021 ggagtagcgg ttcgccctga acaaggcctg atggctctcc gtaaggaact caatctttac
     7081 gctaatattc gtcctgtaaa aatctttgac agtctcaagt atttgtcacc actcaaaccg
     7141 gaacgaattt ctggtgtaga ctttgtcgtg gtgcgtgaat tgacaggcga gatttacttt
     7201 ggagatcata ttcttgaaga gcgcaaagcg cgtgatatca acgactatag ctatgaggaa
     7261 gtggagcgga ttattcgcaa agcctttgaa attgcaagaa atcgcagaaa aatcgttact
     7321 agtatcgata agcaaaatgt tctagcgacc tcaaaactct ggcggaaagt agctgaggaa
     7381 gtcgcacagg atttcccaga tgtaaccttg gaacaccagc tggtagactc agctgctatg
     7441 cttatgatta ccaatcctgc taagtttgat gttattgtaa cggagaatct ttttggagat
     7501 attttatctg atgaatcaag cgtcttatct ggtacacttg aggttatgcc atcagccagt
     7561 cattctgaaa atggaccaag tctctatgaa cctattcacg gttcagcacc tgatattgca
     7621 ggtcaaggaa ttgccaatcc tatttccatg attttattag ttgtcatgat gttgagagat
     7681 agtttcggac gttatgagga tacagagcgt atcaaacgtg ctgttgagac aagtctggcg
     7741 gcaggaattt taacgagaga tataggaggt caggcttcaa caaaggaaat gatggaagct
     7801 attattgcaa ggttatgaag ttagacgaaa aaattactct agtccttttg atttggaatg
     7861 tcatcatttt cttgatttat ggcattgaca aattcaaggc aagaagaaga gcttggcgca
     7921 tcccagagaa aatcttactc attttagccc ttacttgtgg tggttttggg gcctggttag
     7981 ctggaatcac ttttcaccac aagactcgaa aatggtactt taaaacagtt tggtttcttg
     8041 ggatggtgac cacactagta gccttatatt ttatttggag gtaatggatg gtagggtctt
     8101 cgagggaaca cgctgcttgg gctctagcgg actatggttt taaggtcgtg attgcaggat
     8161 ctttcggtga cattcattac aataatgaac tcaataatgg catgttgcca atcgttcagc
     8221 ctagagaggt tagagagaaa ctagcccagc taaaaccaac cgaccaggta actgtggact
     8281 tggaacaaca aaaaatcatc tcaccagttg aagaattcac cttcgagata gatagcaagt
     8341 ggaaacataa actcctaaat agtttggatg atatcggtat taccttgcag tatgaagagt
     8401 tgattgctgc ttatgaaaaa caacgaccag cctactggca ggattagaaa aaatagaaaa
     8461 ggaaatatag taaactgaaa taagatgtaa acaaatgaat tggagcttaa catccatttc
     8521 cagcaatttt ttagaaacta cagtggacta ttctggattc aacacattat aaaattatga
     8581 caaaacacat tcacaagaag gctacgacat tttaaaaggt gagggcggat gtatcgtttg
     8641 ccctactaaa gttggttaca ttatcatgac cagcaacaag gcaggacttg agcgtaagtt
     8701 cgcagccaaa gaacgtaagc gtaacaaacc aggtgttgtt ctctgcggta gcatggatga
     8761 acttcgcgct ttagcgcaac tcaacccaga aattgaagca ttctactaaa aacattggat
     8821 gaagatattc ttcttggttg tatccttcct tggaaaccag aagcctttga aaaactcaaa
     8881 gcatacgggg atggccgtga agaacttatg actgatgtac gtggtactag ctgttttgtt
     8941 atcaagtttg gaaaagcagg tgaacaattg gctgccaagc tttgggaaga aggtaaaatg
     9001 gtctacgcct catatgcttc aatgacaaaa cgattgaaac tcgctatgag agcaaggtgt
     9061 aatggtgtct atggtcgata aggacggcaa actcatccca gaacaaggag gagcacgttc
     9121 aacttcacca gcaccagttg tgatccgtaa agggcttgac attgataaaa tcatgatgca
     9181 cctgtcagat acttttaact catgggacta ctgtcaggtt gagtattatt aagataaaaa
     9241 aagaagtcta gtgttatgag atattaaagc tcctaacact ggactttttg tttagaattt
     9301 cttttctttt tctataggat atggtattct atgtagaaaa tatatgttaa taagtaatgc
     9361 caatatttaa acatcattag taaaaggagt tagattgatg aataaaagaa aagttagttt
     9421 agaagatttt tataaatggt atagtctaaa taaagaagag ttattaaata aggcaactgt
     9481 tggtgaaaag tttaatgata aattaaaaga agagtttctc caggaatggc ctttggatag
     9541 gattttaaca atgtcaatcg atgaatatgt aataggaaag ggacagcaaa ataagtcttt
     9601 atgctacgct cttgagaagg gaaaatacaa aaatctattt cttggaattt ctggtggctc
     9661 agcttcaaaa tttggtattt attggaataa aaaaacaaac aaatataaag atcaagctaa
     9721 taatgagatt tcagagttgg atcagcgatt ttcaaaatta aaatcagatt tgtatgaaat
     9781 tatcaaagaa ggtattcgtt ttaactttga aaatcctatt tttgatatga aaagatcaac
     9841 aaatgaattt attggtcgtt ctgctatggt gacaaaatta ctttgtatct atactgaggg
     9901 agatcctttc tttggtgtaa atattaatag tcagaaagaa ttttggaacc actttgtttc
     9961 tcagacaaat caaggtggac cttatctgca aaatcataaa ataattgaac tggtgtccaa
    10021 aacttatcct gagttggagc catcgaaatt aggaactatg ctttttgagt attctaagct
    10081 ttttatggaa aataaggaag acaatagtac aatggattca tcaaacaatt ttagtcatca
    10141 attaactcaa tctctattaa agtctccaaa ccttatcctt cgtggtgctc ctggcacagg
    10201 aaagacttat cttgctaaag aaattgccaa agaattaacg gatggcaacg aagaccaaat
    10261 cggatttgta caatttcacc catcctatga ttatacggat tttgtagaag gtttaagacc
    10321 agtatcaaat ggggatggag ctattgagtt taggctacag gacggtattt ttaaagattt
    10381 ttgtcagaaa gcaaaagaaa cccaattgat tggaggacaa gataattttg atgaggcttg
    10441 ggattcttac ttagaatata taaatgttgc tgaagaaaaa gaatatataa caaaaacatc
    10501 ttacttatct gttaatagta gacaaaattt gtcagtaaat tatgatagtg gtgttccagg
    10561 atggtcacta cctagcaaat atgtttacga gttgtataaa gataaaaatt ataataagca
    10621 agaatactac aaaagtggtg gaaaaactgt cctagaaaca ttgagaaaga gatttggttt
    10681 gaaagactat gtttccccaa cagaaattga tactgataag aaattcgtct tcatcatcga
    10741 tgaaatcaat cgtggggaga tttctaagat ttttggcgaa ctctttttct ctatcgaccc
    10801 tggctatcgt ggtgaaaaag gaagtgtttc tacccaatat gcaaatctac acgaaactga
    10861 tgaaaagttc tatatccccg aaaatgttta catcatcgga actatgaatg atattgatcg
    10921 ttcagtggat acctttgatt ttgctatgcg tcgtcgtttt cgttttgttg aagttactgc
    10981 cgagggtcaa gttggcatgt tggataaaga gctgaatatc catgcagaag aagcaaaaat
    11041 tcgtctaaga aacttgaacg ctgctatcga aaatgttcag gaattaaaca gtcattatca
    11101 tattggacca agttattttc ttaagttgaa ggatgtagat tttgactatg aattactctg
    11161 gtctgattat attaagcctc tcctagaaga ctacttgcga ggttcttatg atgaggttga
    11221 aactttggaa actttgaaaa aagcatttga actgacaaat aatgagcaaa aagatcaggc
    11281 agtagctgat gacaatgaag gcgatgaaaa cgatgatgcg gattactgat aatcaacaca
    11341 agattattaa agaaaaattt gttgaagaat atcctaaact aagcaatctt cttttagaca
    11401 gaaccttgga aagtctatcc caagatgaac gtattttcat ttttccaaat gatttgactc
    11461 atactcctga tttggataag gaccaaaaga tttttgaaac agtcaatcag aaaatcaaga
    11521 cagggaacgt gattggtttt cttggatatg gtcaggaaag attaacgatt tcctcacgat
    11581 tttctgatga gagtaatgac cattttttgc attatctctt aaacaaggtt cttcatatca
    11641 atctcactag tttagatgtt gctttgtctc gtgaagagag gctttatcaa cttttgatgt
    11701 atctcttccc caagtatcta caagctgcta ttcgaaaagg tctttataag gaataccaga
    11761 gattttctca taacgacagt catgttaagg gagtgattga tgtaagaaac catctcaaga
    11821 aaaatcttcc tttcacggga aatattgcct acgcaacgag agagttcacc tatgataatc
    11881 ccctcatgca gttggtccgt cacactattg aatacattaa gaatcagaaa agcattggtc
    11941 aaggggtact agataatctc tcaactagtc gtgaaaacgt atctgaaatc gtgcgtgtaa
    12001 cgccctctta taaactagct gatcgtgcta agattattcg gggaaatcaa tctaaaccta
    12061 tacgtcatgc atactttcac gagtacagaa acttacaaga actttgtctg atgatcctaa
    12121 accaagaaaa gcacggttta gggtatcaag atcaaaaaat ctatggtatt ctctttgatg
    12181 ttgcctggct ttgggaagag tatgtttaca ccttgttgcc aaaaggtttt gtacatccca
    12241 gaaataagga taagacggat ggaatttcag tattttctgt tgggaaacga aaagtatatc
    12301 cagattttta tgacagagaa cgaaagattg ttctagatgc aaaatataaa aaactggaat
    12361 tgactgaaaa aggaatcaac cgtgaggact tattccagct gatttcctat tcttatattt
    12421 taaaagctga gaaggctgga ctgatttttc ctagtatgga gcagtcagta aatagtgaaa
    12481 taggaaaagt agctggctat ggagctcaat tgaagaagtg gtctattcga atccctcaga
    12541 atgcctcatt ctatagtaca ttttgtaaaa tgatggaaaa ttcagaagaa aattttaaag
    12601 cgattattga tgaagaagtg gggagaaaat aatttcccct ctttctttta tttttaacac
    12661 aagtaaaacc cgaacgatat attttaattc ataaaataat ttgacaaaaa ctgtactttg
    12721 atttataata aattaaggaa acgtcggaaa aggcgtagtg atgcaagagc ataggtaggt
    12781 cattacaaaa gaaacgagac atcgatatgt taaatgaatt tccaattttt gattacgaag
    12841 atattcaatt gattccaaat aaatgtgtca ttaaaagccg tgcagaagcg gatacaagtg
    12901 tcactttagg aaatcacacc tttaaactac ctgttgtgcc agcgaatatg cagacgattt
    12961 tggatgaaaa tgtagcagag caactggcta aaggtggtta cttctacatt atgcaccgtt
    13021 ttgatgaggc aggacgcatt ccttttatta aacgaatgca caatcaaggg ctcattgctt
    13081 ctatctctgt cggtgttaag gattatgagt atgattttgt tagccagctc aaggctgata
    13141 ctcctgagta tatcactatt gatattgctc atggtcatgc ggatagcgtg atttctatga
    13201 ttcaacacat caagaaagaa ttgccagata cctttgtcat tgctggaaat gtgggaacac
    13261 cagaagctgt gcgtgaattg gaaaatgctg gtgcggatgc tactaaggtc ggaatcggtc
    13321 ctggtaaggt ttgtatcacc aaggttaaga ctggttttgg tacaggtggt tggcagttgg
    13381 ctgctctacg ctggtgtgcc aaggctgcgc gtaaaccgat tatcgctgat ggaggaattc
    13441 gtactcacgg tgatattgcc aagtctatcc gcttcggtgc tagcatgatc atgattggtt
    13501 ccctctttgc aggacacatt gaaagtccag ggaaaacgat tgaagtcgat ggtgaacagt
    13561 tcaaagaata ttatggttca gcctcacaat atcaaaaagg tgcttacaaa aatgtggaag
    13621 gcaaacgtat cttgcttcct gctaaaggtc atctgcaaga cactttaact gagatggaac
    13681 aagaccttca aagtgctatt tcttatgcag gtggacgtca ggttgctgac cttaaacacg
    13741 ttgattatgt gatcgtgaaa aactccatct ggaatgggga tgcttcccac taagacgggg
    13801 tctttgacca aaaaacttgt tattagagca aatttctgtt ataataaaac aagtttccac
    13861 ccttagtgta atggatatca cgtaagattc cggttcttga gatgggggtt cgattccctc
    13921 agggtggatg taaacatcct aaaaagcctt taatagggct tttttcttta tcctgaccca
    13981 aatttgccgc taaaactgag aatctctgtc taaagaattc ccaaatgctt tccagtcccg
    14041 ttttagagtg actcaggggg ctttttttga tataataaaa aggactatta tcagttagaa
    14101 agaggttggt atgaaagaat tacaaactgt actaaagaat cattttgcaa tcgaatttgc
    14161 agacaaaaat ttactggaaa ctgcctttac tcatacgagt tatgccaatg agcaccgcct
    14221 cttaaaaatt tcacacaatg aacgcttgga atttttagga gacgctgttc tacagttatt
    14281 gatttcagaa tatctatata aaaaatatcc taaaaagcct gaaggtgacc tatcaaaact
    14341 ccgtgctatg attgtccgtg aggagagttt agctggtttt gcgcgtgatt gccagtttga
    14401 ccagtttatc aagttgggta aaggggaaga aaaatctggt ggtcgcaatc gtgacaccat
    14461 tcttggtgat gcctttgaag cctttcttgg tgcccttctt ttggataagg atgtggccaa
    14521 ggtcaaggaa tttatctatc aagtcatgat tcctaaggtt gaagcaggcg aatttgagat
    14581 gattacagac tataaaaccc atctccaaga gttacttcag gtcaatggtg atgtggctat
    14641 tcgttatcag gtgatttctg aaacagggcc tgctcacgat aaggtctttg atgtagaagt
    14701 tcttgttgaa ggtaagagca tcggtcaagg ccaaggtcgt tctaagaaat tagcagagca
    14761 ggaagctgcc aaaaatgccg ttgagaaggg gctggattca tgtatttaaa ggaaatcgaa
    14821 attcaggggt tcaagtcttt tgctgataag accaaggtcg tttttgacca aggtgtgacg
    14881 gcagttgttg gacccaatgg atctggaaag tccaatatta cagaaagtct gcgttgggct
    14941 ttgggggagt ctagtgtcaa gagtctccgt gggggcaaga tgccggatgt catctttgct
    15001 ggaaccgaaa gtcgcaaacc gctcaattat gcttctgtag ttgtgactct ggataatcat
    15061 gacggattta tcaaggatgc aggtcaagaa atcagggtgg aacgccatat ctatcgtagt
    15121 ggagatagcg aatacaagat tgacggcaag aaagtccgtc tgcgtgatat tcatgacctc
    15181 ttcttggata ctggattggg acgagattcc ttctctatta tttcccaagg gaaggttgag
    15241 gagattttta attccaagcc tgaggaacga cgagctattt ttgaagaagc tgcaggagtt
    15301 ttaaaataca agactcgcag aaaagaaact gagagtaaac tgcaacaaac tcaggataat
    15361 ctagaccgct tagaggacat tatctacgag ttggataatc aaatcaagcc tcttgagaag
    15421 caagctgaga atgcctgtaa gtttttagac ttggaaggac aacgtaaggc tatttattta
    15481 gacgttctgg ttgctcaaat caaggaaaat aaggcagaac tagagtcgac agaagaagag
    15541 ctggctcagg ttcaagaact cttgatgagt tattaccaaa agcgtgaaaa attagaagaa
    15601 gaaaatcaaa ctcttaaaaa gcaacgccaa gatttacagg ctgaaatggc caaagaccaa
    15661 ggcagtttga tggacttgac tagtctgatt agtgatttag aaagaaaatt agccctatcg
    15721 aaactggagt ccgagcaagt ggccttgaat caacaggagg cacaagctcg tttggctgct
    15781 ttggaggata agagaaattc actcagcaaa gaaaagtctg ataaagaaag ctctttagct
    15841 ctgttagagg gaaatctagt ccaaaataat caaaaactca atcgtttaga agctgaattg
    15901 ctggctttct cagacgatcc tgatcagatg attgagctct tacgtgaacg ctttgtagct
    15961 cttttacaag aagaagcgga tgtctcaaac cagttgaccc gtattgagaa tgagttggaa
    16021 aatagtcgtc agctttctca aaaacaagca gatcaactag aaaagctgaa agagcaatta
    16081 gctatagcta aagagaaggc tagtcagcaa aaggaagagc ttgaaactgc caaggagcag
    16141 gttcagaaat tattggctga ctaccaagct attgccaagg agcaagagga gcagaaaact
    16201 tcctatcaag ctcaacaaag ccaactcttt gaccgtctgg ataatctcaa aaacaagcag
    16261 gccagagctc aaagtttgga aaatatcctg agaaatcata gtaactttta tgcaggtgtt
    16321 aagagtgttc tccaagaaaa agatcgccta ggtgggatta ttggtgcagt cagtgagcat
    16381 ctgacctttg atatgcatta tcaaactgcc ctagaaattg cgcttggagc gagtagtcag
    16441 cacattattg tagaagatga gaatgcggca accaaggcta ttgacttcct taaacggaac
    16501 agagccggtc gtgcaacctt tcttcctttg accactatta aggcgcgtac gatttctagt
    16561 cagaaccaag atgctatcgc tgtaagccca ggtttccttg ggatggcaga tgagttggtg
    16621 acttttgata ctagactgga agccattttc aagaacttgc tagctacgac ggctatcttt
    16681 gataccgtag aacatgcgcg tgaagctgct cgacaagttc gttatcaggt tcgtatggtg
    16741 acattggatg ggacagaatt acgcacgggt ggttcctatg cgggtggtgc caatcgccaa
    16801 aataacagta ttgtcatcaa gccagaactg gagcaattac aaaaagaaat tgctgcagat
    16861 gaagcaagct tgggttcaga agaagcggct ttgaagacct tgcaagacca gatggctgca
    16921 ttgacagaaa gattagaagc catcaaatct caaggagagc aggcacgtat tcaggagcaa
    16981 ggcttgtccc tcgcttatca gcaaactagt cagcaagttg aagaactgga aactctttgg
    17041 aaactccaag aagaggaaat agatcgtctt tctgagggag attggcaagc ggataaggaa
    17101 aaatgtcaag agagccttgc tactatcgcc agtgaaaagc aaaatctgga agctgagatt
    17161 gaagaaatta agtctaataa aaacgccatc caagaacgct atcaaaattt gcaggaagag
    17221 gtggcgcaag ctcgcttgct taagacagaa ctgcaagggc aaaaacgtta tgaagtagct
    17281 gatattgagc gtttaggcaa ggaattggac aatcttaata tcgaacaaga agaaattcag
    17341 cgcatgctcc aagaaaaagt tgacaatctt gagaaggttg atacagaatt gctcagtcaa
    17401 caggcggaag aatccaaaac tcagaaaaca aatctccaac aaggtttgat tcgcaagcag
    17461 tttgagttgg atgatataga aggtcaactg gatgatattg ccagtcactt ggatcaagct
    17521 cgccagcaga atgaggagtg gattcgcaag caaacacgtg ctgaagccaa gaaagaaaag
    17581 gtcagcgagc gcttgcgcca tctacaaaat caattaacag accagtacca gattagctat
    17641 actgaagcac tagaaaaggc acatgaattg gaaaacctca atctggcaga gcaagaggtg
    17701 caggatttag agaaggctat tcgctcattg ggacctgtca acttggaagc tattgaccag
    17761 tacgaagaag ttcacaaccg tctggacttt ctaaatagtc agcgagatga tattttgtca
    17821 gcgaaaaatc tgctccttga aaccattaca gagatgaatg atgaggtcaa ggaacgcttt
    17881 aaatcaacct ttgaagctat tcgtgagtcc tttaaagtga ccttcaagca gatgtttggc
    17941 ggaggtcagg cagacttgat attgactgag ggcgaccttt taacagctgg tgtggagatt
    18001 tctgttcaac ctccaggtaa gaaaatccag tcgcttaacc tcatgagtgg tggtgaaaaa
    18061 gctctatcgg ctcttgcctt gcttttctcc attattcgtg tcaagaccat tccttttgtc
    18121 atcttggatg aggtggaagc tgcgctggat gaagccaatg ttaaacgttt tggggattac
    18181 ctcaaccgct ttgacaagga cagccagttt atcgttgtaa cccaccgtaa gggaaccatg
    18241 gcagcggctg attccatcta tggagtgacc atgcaagaat cgggtgtttc aaagattgtt
    18301 tcagttaagt taaaagattt agaaagtatt gaaggatgac aattaaacta gtagcaacgg
    18361 atatggacgg aaccttccta gatgggaatg gacgctttga tatggatcgt ctcaagtctc
    18421 tcttggcttc ctacaaggaa aaagggattt actttgcggt ggcttcgggt cggggatttc
    18481 tgtctctgga aaaattattt gctgatgttc gtgatgacat tattttcatc gcggaaaatg
    18541 gcagtttggt agagtatcaa ggtcaggact tgtatgaagc gactatgtct cgtgactttt
    18601 atctggcaac ttttgaaaag ctgaaaacgt caccttatgt agatatcaat aaactgctct
    18661 tgacgggtaa gaagggttca tatgttctag atacggttga tgagacctat ttgaaagtga
    18721 gtcagcatta taatgaaaat atccaaaaag tagcgagttt ggaagatatc acagatgaca
    18781 ttttcaaatt tacaaccaac ttcacagaag aaacgctaga agctggtgaa gcttgggtta
    18841 atgaacatgt ccctggtgtt aaggccatga caactggctt tgaatctatt gatattgttc
    18901 tggactatgt cgataagggt gtagctattg ttgaattagc taaaaaactt ggtatcacaa
    18961 tggatcaggt catggctttt ggagacaatc ttaatgactt acatatgatg caggttgtgg
    19021 gacatcctgt agctcctgaa aatgcacgac ctgaaatttt agaattagca aagactgtga
    19081 ttggtcacca taaggaacgg tcggttatag cttatatgga gggcttataa tggcagatat
    19141 aaaattgatt gcattggact tggacgggac cttgctgact actgataaaa ggctgacgga
    19201 tcgtaccaag gaaaccttga aagctgcgcg tgatcgtggt atcaaggtcg tattgacaac
    19261 tggtcgtccc ttaaaagcca tggacttctt tctccatgag ttagggactg acggccatga
    19321 agatgagtat accattactt ttaatggtgg attagttcag aaaaatacag gagaaatcct
    19381 tgataaaaca gtcttttcat atgatgatgt ggcacgtttg tatgaagaaa cagagaaatt
    19441 atcactgcct cttgatgcca tctcagaagg aacagtttat caaatccaat cggaccaaga
    19501 aagtctttat gccaaattca atccagcttt gacctttgtt ccagtggact ttgaagactt
    19561 atctagtcaa atgacctaca acaaatgcgt gactgccttt gctcaagaac ccttggatgc
    19621 agccattcag aagatttctc cagaattgtt tgaccaatat gaaatcttta aatcacgtga
    19681 aatgttgcta gaatggtcac caaagaatgt tcataaagca acaggtttgg caaaactaat
    19741 cagccatctt ggaatcgacc aaagtcaagt gatggcttgt ggtgacgagg ccaatgacct
    19801 ctctatgatt gaatgggcag gtcttggtgt tgctatgcaa aacgctgttt ctgaagtaaa
    19861 ggcagccgca aatgtagtga cgccgatgac caacgatgag gaagctgtcg cctgggctat
    19921 cgaagaatat gtgctaaagg agaactaaga tatgggattg tttgaccgtc tattcggaaa
    19981 aaaagaagaa cctaaaatcg aagaagttgt aaaagaagct ctggaaaatc ttgatttgtc
    20041 tgaagatgtt gatcctacct tcacagaagt tgaggaagtt tctcaggaag aagcagaggt
    20101 tgaaattgtt gaacaagctg tgttccaaga agaggaaatc caagacacag ttgaagaaag
    20161 tctggattta gagccagttg tagaagtttc tcaaaaagaa gtcgaagaat ttccacactc
    20221 agaagaaggg aatactgagt ttctagagac tatagaagaa aataattctg aagttcttga
    20281 agcagaaagg cctcaagcag aagaaaccgt tcaggaaaaa tatgaccgca gtcttaagaa
    20341 aactcgtaca ggtttcggtg cccgcttgaa tgccttcttt gctaacttcc gctctgttga
    20401 cgaagaattt ttcgaggaac tggaagaact gctgattatg agtgatgttg gtgtccaagt
    20461 cgcttctaac ttaacggagg aactacgtta cgaagccaag cttgaaaatg ccaagaaacc
    20521 tgatgcactt cgtcgtgtca tcattgagaa attggttgag ctttatgaaa aggatggtag
    20581 ctacgatgaa agcatccact tccaagataa cttgacagtt atgctctttg ttggtgtgaa
    20641 tggtgttggg aaaacaactt ctatcggaaa actagcccac cgctacaaac gagctggtaa
    20701 gaaggtcatg ctggttgcag cagatacctt ccgtgcgggt gcagtagctc agctagctga
    20761 atggggccga cgagtagatg ttccagtagt aactggacct gaaaaagctg atccagccag
    20821 cgtggtcttt gatggtatgg aacgtgccgt ggctgaaggt atcgatattc tcatgattga
    20881 tactgctggt cgtctgcaaa ataaggataa ccttatggct gagttggaaa agattggtcg
    20941 tattatcaaa cgtgttgtgc cagaagcacc acatgaaacc ttcttggcac ttgatgcatc
    21001 aacaggtcaa aatgccctag tacaggccaa agaattttcg aaaatcacac ctttaacggg
    21061 aattgttttg actaagattg atggaactgc tcgaggaggt gtggttctag ccattcgtga
    21121 agaactcaat attcctgtaa aattgattgg ttttggtgaa aaaatcgatg atattggaga
    21181 gtttaactca gaaaacttta tgaaaggtct cttggaaggc ttaatctaat cagaagcaaa
    21241 aatcctgcaa ggtacaaact tgcaggattt ttttattcga aacgaccatc ttgacgatag
    21301 gcgatatctg gttgccaagt ccatttggca tcgaattttt caagtaggtc aaagctggct
    21361 tgaggtccca tgcttccagc tttatagtca tgaagtgggg caccattttc ggcccagagc
    21421 tcttcaatac ggtcaatcaa cttccatgac gcaccaactt catcccagtg gctaaagtta
    21481 gttgagttgt tatttaggac atcataaatc aatttttcgt atggttctgg agaagcacca
    21541 gttgcagtcg catctgtacg gtaatcaagt gagttaggag ccaagttaaa ttcttctcct
    21601 acttgcttcc catttaggct aagagagaag ccttctgttg gttgaatata gatggtcaaa
    21661 atatttggag caagtggttc tccaaagata gaatccattt gtttaaagac gatgttgaca
    21721 tgggttcctt tttcagtcag tcgtttacct gtacggaaaa agaaaggaac accacggaat
    21781 cgatcgctgt ctacaaagaa ggcacctgat gtaaaggttt cagttgttga ttctggattc
    21841 acatttggct cgctacgata agagatgtat ttcatgccat caatcttacc agagcggtat
    21901 tgcccacgga taaagtgttc tttgagttct tcatcagttg gatgatagag gtttttaaag
    21961 accttaatct tttcagcacg aatctcgtct tttgtgaagc ttgctggttt gtccatggcg
    22021 aggagcgaaa gaagttgtag agtgtggttt tggaccatgt cacggagggc accggattgg
    22081 tcatagtagc caccacgttc ttctacaccc aagcgctccg caaaggtaat ttgaacattg
    22141 tcgataaaat ccttgttcca aacgttttca aaaatcaagt ttgcaaagcg aactgcaaag
    22201 atgctttgga tcatttcctt accaagataa tggtcgatac ggaaaatttg ttcttcgtca
    22261 aatgttgcta ggagttcgtc attcaacttg tttgcagttg cgtaatctgt accaaatggt
    22321 ttttcaacga tcaagcgctc aaaacctttg ccatcgacaa tgttttcaga tttgaggtgt
    22381 ttggcaatgg ttccaaagaa ctgaggtgcc atagacaaga agaagagctt attgtgttca
    22441 gcttggtatt tttcattaag ctcagcttgt aattgacgca aagcaatata atgttccgaa
    22501 tcattgacat catggctttg atagtagaag tggctagcaa attcttgggc ttgctcggta
    22561 ctatctgcca aatcaaggat ggactcgaca actacagatt caaaatattc cttactccaa
    22621 ggtctacggg cagttccaat aacggcaaag tgcttggaaa gattgccgga tttatatagt
    22681 ctaaaaaggg aagggtagag cttgcgttta gccaggtctc cactcgcacc gaaaattgta
    22741 acaataacct tagatgacat ctagctacct aatttctatt tttattccta gtcttgctag
    22801 gtatgaggaa acctcatttc ataaacttaa ttctaacata attttccgaa aaatcaaaaa
    22861 ttccaatacg aggtagaaaa actgcaagga aatccttaca gtttgagttt agacgtttaa
    22921 gaccttatct aagaactctt tcagacgagg gtgttgtggg ttatcaaaga tttggtcagg
    22981 tgttccgtct tcaaggaact cgccatctgc agtaaagata acgcggttgg caacctgacg
    23041 agcaaatccc atctcatggg ttacgataat catggtcatg ccttgctcag ccaattcctt
    23101 cataacgtta agtacgtctc caaccatctc agggtcaagg gcagaagttg gttcatcgaa
    23161 gagcatgatg tctggattca ttgctaggcc acgagcgatg gccacacgtt gtttttgacc
    23221 acctgatagg ctatctggat tggcattagc tttatctgct agtccaacct tttcaagcaa
    23281 ctccattccc aattcctcag cttcttcctt agtcatcaac ttgtgctcaa taggagcaaa
    23341 ggtgatgttg tccaatacag acatatgagg gaagaggttg aagtgttgga ataccatgcc
    23401 gatattttca cggacgtggt caacattggt tgttttttca gttaaatcat agccgttcac
    23461 agtgatgtga ccgctagtga cttcttctaa aagattgagg ctacggagga aagttgactt
    23521 accagaacct gaaggaccga tgatacaaac aacatctcct tcatagaact tagtcgtaat
    23581 tccttttagg acttcatttt ttccatagtg cttgtgtaaa tcatttacat caatttttaa
    23641 ttttgccatt aacgaatcct cttttctaag cgtttcgcta gtctagtcaa aagtgtgata
    23701 attacaagat agaagatagc aaggattgca tacatcttga aactttggta gttacgagca
    23761 atgataatct taccagtttg gaagagttca accaaaccga tagcagatac gatagttgta
    23821 tctttaagag cgataacgaa ttggttgaca aagtttggca acatcaattt agttgcttgt
    23881 ggcaagataa tcttacgcat ggtttttcca taagagatac ccaagcttcg gctggcttcc
    23941 atttggccaa ctggaacggc ctgaatacca ccacgaacga tttcagcgat ataagcagcc
    24001 gcattgagtg agagggcaat ggttccagct acaaagtcgt taattgggct ttgttggcct
    24061 gtgatagact cgatgaagtt tggaattccc cagaagatga aggctgcaag aatcatcaat
    24121 ggaataccac gaataacgtc aacgaaaatc tcagagatga cgcgaagaga tttgtatggg
    24181 ctaacgctaa acataccgaa gataattccg atgacaatgg caatagcaaa tgagataaga
    24241 gctagagcaa gagtgatacc aagaccgcta aggagttgtt tgtagttgtt ttgaagcaag
    24301 ccccagagcg ttgtttcgtc aacagtactt gttgaagcag ttgaagattc gctagctagg
    24361 tatttgtcaa gaatcttttg gaattcaccg tttgccttaa ggtttgcaag tccgttgttg
    24421 aacatttcaa tcagttctgg atttgctcct tttttaacgg caaaggctgt ttcaccgatt
    24481 ggagttccag agattggagt tttcaatttt tgaccttggc tgatagaata tttgagaaca
    24541 ggttcatcat ccataacggc atcaatggca ccagtgttta aactgtcata cattgaagaa
    24601 ccatcagcaa aggttttgat tttgtaaccg tatttgcttt gattttctgt taggaaggtt
    24661 tgagaagcag ttccgttttt aacaccgact gtctttcctt ttagatcttc ataagaagca
    24721 atattgcttg attctttgac accaagaatg gtattagcag tgtagtatga ttctgagaag
    24781 tcaaaagttg ccttacgagc atctgtgaca gacataccag caatgatacc atcggcttga
    24841 ccagcttgga cagcactgat agcagcatca aaaccagggt tggtgatttc aatttcaaaa
    24901 ccttggtctt tagcgattgc cttaatcaat tccatatcaa taccagtgta ttggttgctt
    24961 gaattttgga aaacaaaagg tgcaaaagaa gaatcgctgg caatgatata tttagcctta
    25021 acaggaatag cttttaatcc tgcgagagta gttgtagttg gcactgctga agatgatgaa
    25081 gcagtccatt tcttgataat tttatcaaga ctaccatctt ttttcatttc agccaaggct
    25141 tggttaaatt cagtaaccag gtgctcgtat ttacttcctt ttttcacacc gaaagcaaaa
    25201 cttcctacag cttcaccatc catttcaata tggaggtctt gaccttggtt aatggcatat
    25261 tcgataacag gtttgtcatc catcatggca tcgatggcac cagcactcaa gctgttgttc
    25321 attaaatcac cagtgtcaaa tgttttaata gtaaagccgt atttatcttt gattgtttca
    25381 aggaaacgtt gagcggcagt tccgttttta acaccaacgg ttttgccagt taattggtcg
    25441 tacttgctaa ttttgtgtga ctttgtagta gcaatgacaa cttttgtatc atagtaagta
    25501 tcagacatgg tgaagacttt ttcacgttct ttagtctttg tcatccctgc catgatagcg
    25561 tcggcttgcc cagcttgaac cgcattgacc gctgcgtcaa atccaggata ggacatctga
    25621 atgttccagc ctttaatctc agcgactttg ttaataatgt caacatcaat tcctttataa
    25681 gtttgatctg aatctttaaa ctcaaaaggt gcataggcgg tatcagaaac aatcttaatc
    25741 gtttctgctt tggcaatacc taatgagaaa attgggaata aaattagcaa aaatgctaga
    25801 aattttttct tcatttttag tctccttttc cgaatattct ctcattatat cagaaaaagt
    25861 aaaaaaaggc aaatttttat attttccgtg tcagaaaata taacattgat ttttcctttt
    25921 ctttcttgaa ttgctattaa aaagtgctat aataatagta tatatagaag aaaagaggac
    25981 ggggatatga agaataaaag aatatttaaa gacttccaag cttcaaaaat gaatttaaac
    26041 atttacacaa gccccttgtt agcctttgtt tttgtcttca taggagagtt tgtggcttat
    26101 actttatatg gtattagttt gttagctctc atcggacttg ctagaaattt tggagaggct
    26161 ggtcaaaatc ttgcaagcta cttgcagacc ttgcatcaga gcttgacgga taaaacaagt
    26221 gactttcgtt taattttagg attactggcc tttggtttta ttcttaacac tgtgttcaga
    26281 tggacaagaa aagttgagaa aagacctatt cgaaccttgg gattttatag agagaatttc
    26341 ctcagcaatc ttctgaaagg atttagtcta ggcctggcac tttttcttct gaccttgtta
    26401 ggtttagtgg tcttaggtca atatcgtttg gaatccattc acttgaatcc ttattctctt
    26461 gcctttgtcg tctttactat cccattttgg attttacagg ggacagcaga agaagtggtg
    26521 gcccgtgctt ggctacttcc tcaattggcc tcaagaacca atctaaaact agctattctt
    26581 atatctagcc tgttctttac cctgcttcat atgggcaatt ctggcctcac ccctctatct
    26641 ctagtaaatc tctttttatt cggagttgcc atggctcttt accttctcaa aactgataca
    26701 gtttggggtg ttgcaggtat tcatggtgct tggaattttg ctcagggtaa tctctttggg
    26761 attttagtta gtggtcaacc gtcaggaacg tctctgatga cctttttacc acaaggcaat
    26821 caagattggc tatcaggtgg ttcttttggc atagaaggtt ccattatgac aagtctggta
    26881 ttactactgc tgattgtcta tcttgctaat aaattaaaga aagaaaatga aaggatgtga
    26941 cttcggtccg tccttttctt cgtgaaaata ctataagtat gctaaaatag gaatagcaca
    27001 tggagagagg attcttatga tcaatcacat tacagataat caatttaaac tagtatcaaa
    27061 atatcaacca tcaggagatc aaccccaagc tatcgagcag ttggtggata acattgaggg
    27121 gggagaaaaa gctcagattc tgatgggggc gactggaaca gggaagacct atactatgag
    27181 tcaggtcatt tctaaagtca ataaaccaac tctggttatt gcccacaata aaactctggc
    27241 tggtcagctc tatggggagt ttaaggaatt tttccctgaa aatgcagttg agtatttcgt
    27301 atcctactat gattattacc agccagaggc ctatgtccct tctagcgata cctatattga
    27361 gaaggatagt tctgtcaatg acgagattga caagcttcgc cactcagcta cctcagccct
    27421 tttggagcgt aatgatgtta ttgtcgtggc ctcagtctct tgtatctatg gtttgggttc
    27481 gcccaaggaa tacgctgata gtgtcgttag tctccgtcct ggtctagaga tttctcgtga
    27541 taaactcttg aatgacttgg tcgatattca gtttgaacgc aatgatattg atttccaacg
    27601 cggaagattt cgcgttcgtg gggatgtggt agagattttc ccagcttccc gagatgaaca
    27661 tgcctttcga gtagaatttt ttggagacga aattgaccgt attcgtgaag ttgaggctct
    27721 gacaggtcag gtgttgggag aagtggatca tttagcgatt ttcccagcga cacactttgt
    27781 gaccaatgac gaccacatgg aagttgccat tgcaaagatt caggccgagt tggaagaaca
    27841 attagctgtc tttgaaaagg aaggtaaact gcttgaagcc cagcgtttga aacagcggac
    27901 agagtatgat atcgaaatgt tgcgtgagat gggctatacc aatggggttg aaaattattc
    27961 tcgccacatg gatggacgga gcgaaggaga gcctccttat acgcttctcg acttcttccc
    28021 agatgatttc ttgattatga ttgacgagag tcatatgacc atagggcaaa tcaagggcat
    28081 gtacaatgga gaccgttcgc gtaaagaaat gctggttaat tatggtttcc gtttgccgtc
    28141 tgctttggac aatcgtcctc tacgtcggga ggagtttgag agtcacgttc atcagattgt
    28201 ttacgtttca gcgacacctg gtgactatga aaatgaacag accgagacag tgattgagca
    28261 aatcattcgt ccaacgggac tcttggatcc agaggtggaa gtccgtccga ctatgggaca
    28321 gattgatgac ctcttgggtg aaatcaatgc ccgcgttgaa aaaaatgagc gtacctttat
    28381 cacaactttg accaagaaaa tggcagagga cttgaccgac tacttcaagg aaatgggtat
    28441 caaggtcaag tacatgcact cggatatcaa gaccttggaa cggacggaga ttatccgtga
    28501 cctgcgcttg ggtgtctttg atgtcttggt cggaattaac ctgctccgtg aaggaattga
    28561 cgttcctgaa gtgagcctcg tagctattct cgatgctgac aaggaaggtt tccttcgcaa
    28621 cgaacgtgga ctcatccaga ctattggacg tgctgctcgt aacagtgaag gccatgtcat
    28681 catgtatgca gacacggtta cccagtctat gcaacgtgct atcgatgaaa ctgcccgccg
    28741 tcggaaaatt cagatggcct ataatgaaga gcatggtatc gtaccacaga caatcaagaa
    28801 agaaatccgt gacctgattg ccgtgaccaa ggcagttgct aaggaagagg acaaggaagt
    28861 cgacatcaat agcctcaaca aacaagagcg caaagaactc gtcaagaaac tagaaaaaca
    28921 aatgcaagaa gccgtcgaag tgcttgactt tgaactggcg gctcagatcc gtgatatgat
    28981 gttggaagtc aaggccttgg attaggggaa tagtatgatt tatttaagaa agttaaagag
    29041 agaagatttg atgtctttat gggaaatggc ttattcacaa cttaatccag tttggaaaca
    29101 gtatgatgct ccctattatg atgattatca gtatttttca aattttaaag aattcgaact
    29161 acaaaaatca gaatccattt taagcaactc aaatcgcctt ggtatttttg ttgatgataa
    29221 actagttggg actgtttcgc gttattgggt atgtaaacaa acaagatgga tggaattggg
    29281 aattggtatt tatgataaaa aattctggaa cactggtatt gggaaagttg ctatgttgca
    29341 gtggatagat aggacgtttc aggattactt ggagttggag catctgggtt tgacaacttg
    29401 gtcaggaaat cttggtatga tgaaacttgc tgaaaaatta agaatgaaaa aagaagctca
    29461 tattccaaaa gttcgttatt atcaaggtaa atattttgat agtattaaat atggtatttt
    29521 gagagaagac tgggagaaaa tgaatgacgg ttattatcaa atcaatggaa actcctgaag
    29581 agatagaagg taaatccctt gttcactggc aaacgtggag agaggcttat gatgaccttt
    29641 tgcctgcaga atttcaggag acaatgacat tagaaagatg tcgattcttt agtcaaaagt
    29701 atccagaaaa tacattgatt gcgataggtg atctgaaggt agttggtttt atcagttatg
    29761 gtaactttcg tgatgagact attcaagctg gtgaaattat tgctttatat gttttaaaag
    29821 actattacgg aaaaggcata gcacaaaagt taatgaaagc agctttgact gctctgaatc
    29881 atttttctga aattttctta tgggtattga aagataacaa gcgagccatt gctttctatc
    29941 aaaaaatggg ttttactttt gatggacaag aaaagatact tgaacttgga aagcctataa
    30001 aggaaaaacg aatggtattc tattctaaaa taattttaaa aagtagaagc taatggcact
    30061 ggtaccaagt ctgaaaattt aataaattag aaagcgagta aatttatgtc ccgttcccaa
    30121 ttaacgattt taacaaatat ttgtctgatt gaagaccttg aaactcagtg cgtggttatg
    30181 cagtaccgtg ctcctgaaac caatcgctgg tctggttatg cctttcctgg aggtcatgta
    30241 gaaaatggtg aggcttttgc ggagtctgtc attcgtgaaa tctacgaaga aacaggattg
    30301 actatccaaa atccgcaact ggtaggtgtt aaaaattggc ctttggatac aggggggcgc
    30361 tacattgtct tttgttacaa ggcgaccgag tttactggaa ctcttcaatc ttcagacgag
    30421 ggagaagttt cttgggtgca aaaagaccag attccaaact tgaatctggc ctatgatatg
    30481 ctaccattga tggaaatgat ggaagctccc gacaagtcag agtttttcta ccctcgccgt
    30541 acagaagacg attgggaaaa gaaaatcttc tagtctttta ctaaataacc tagctgatcc
    30601 aaggcttcct cgatatagtg gaggtcttgt tgtgtttcgg cttcgactag gtggtaatgg
    30661 atgccatctg tcaattcaga tagaggtcta aagtcagaat gctcgacttg ttctagaaaa
    30721 tgttgcacat ctctgcgaca agacagttta agcaaggttt caatttctcc ataaacggga
    30781 tggtcaatca aggtattctg gacatgccca ccattatcga caatagcaag gagttcctga
    30841 ccgatttctt caacttgatg tttcactttg aaaagtttgt gaacataagg attggtatca
    30901 atttgcttat agatgtagcc acgattggtg gataggatag gagcgccatc ggctctcaaa
    30961 attgcaatgt cctgcacaat gacctgacgt gtgacatgaa aatgttccgc caaactttgg
    31021 ccattaaggg ctttaggagc ttctttcaag agttggagca gggcttgttt gcgatctttt
    31081 gtcatagctt ttccttttaa cggcgttttc gaagcacttt atagacagct agtgctaatg
    31141 tatagtctac catactatgg ataattgtgc caaatccaac tagtacaaat agaacataga
    31201 acatgttttc tacattggta cccgaagttg cgtaaaaaag gacacaggct aatacttcag
    31261 caagggcatg aacaacagcc aaaacaaaat tgaaaaccca ggaagatttt ggtttatcta
    31321 gggtatcggg gaatttttgt aggtaaagag ctcctaaagc accaaaagat atatgggaaa
    31381 aagcccgaaa aacgataacc atgggatagc cagccatcaa aaatccaaaa ctagaggcta
    31441 ggatgacaaa aactgccatc aagggcgaca agaacatggc tataaaaata gcgatgtggc
    31501 tccccaaagt ataggaagca ggtggaatga caatcttgaa aggcataaca attggaatca
    31561 aaatcgcaat agccgttaaa agggctgtca ttgtcataaa ttgtgtcttt ttccgtgtat
    31621 tcacaagaat ctccttttta actgcatata cactagtatg gtacaataaa ccagacaata
    31681 aagcaagaat ttacttgggt ttatagatca ttttttagtt aaaagttata gtagattgaa
    31741 actagaatag tacacctcta cttctaaaac attgttagaa atcgatttga ctgtcctgat
    31801 cgatttgtcc tgttcttatt tcgttttact atagtaaaga tttcattaaa aagaaactgt
    31861 atagagcaaa atctccacct tcaggtttga aagcggagat tgtttttatt ttttcaaggt
    31921 ttgtagtcgt ggaacaatgg ctagggttag aattgcagaa atgaccaatt cagcaattga
    31981 atttgttgag ataacggttg ccagaagaag ttggatattt ccattataaa catttccaaa
    32041 taggaagaag attcctccaa ggacaaagat agtatttgtc aaggaaccaa gggctccagc
    32101 taaaatcaga ccagtcttgt ttttcatcag tttatagact aagtaaggag ttaaaccaat
    32161 caaaatacgt gggacgatgg caatgatagc tgagtagatg tttccgtttg gtacgaaggg
    32221 agagaagagg tagcttgtcg gtagaatcgt aatcgtgtta accgtcaagc taagtagccc
    32281 catcaaaaat ccaagtgtaa ccccaactcg tggaccataa ataatgctgg caataatgac
    32341 aggaatatga acaatggtcg gtttgattgg aaatggaaaa aggttaaaga taagtgagct
    32401 cagaaagtgt atcacgagca tggtagcaaa aaagatagca atgggtgcaa tattagagcg
    32461 ttttttcatc gagagtttcc tttattcttt ctaaaataat tgtgaggtca gctaaagctc
    32521 ctcgtccgtg gtctccacaa gctagtaggg attccttagg agcaatcagc tgatagccgt
    32581 aggtttctaa tgttttcaga ttattctgag ttactggatg gtcatacatt tttgtattca
    32641 tagcaggagc tattagtttg ggaatatgac ttggcagggc tagagctgta ctggttacca
    32701 tgttgtccgc aaatccgtga gctagttttg caatagtgtt agcagttgca ggtaccacga
    32761 taaataaatc tgcttttttt ccaagttcga tatgattgac ctgatcagga tagggttcct
    32821 tcatgacatc caagtggaca ggattctgtg agagtacctg tagtgtcaaa ggttggataa
    32881 actctgtagc agcctgagtc attaagacag tgacttgatg gccttgtttt tttagagaac
    32941 tgactaaatc tgccgactta taagaggcga ttgaacccgt tacagccaag agaatgtttg
    33001 ccatagtttt cctttctaag aatgataggc ttgaattttt tcaaggagga gttctgcaat
    33061 ttcttcttta gtctggactg tttgaagctg atttttctca acaaatatag ctcggtgctg
    33121 acctgctgaa atttgagtca ggtcattcgc gatgattaaa tctgcttgat tcttgataag
    33181 actttttcgt gcaatgtcaa ccagatgatc ttcggtaaca tcaaccagca gtttgaaacc
    33241 aatcagatga atagtaggat tccattcctt gactagggat atgattttgg gtgtcttttt
    33301 aaggaacaaa acctgaacct catcagttga agaaatcttg gcctgatgat tctgcttgct
    33361 taaaaattct tttagattgg agctagcctg aacttcctca agccctgtca tataaacagg
    33421 agtgtagtca gaaacagcca ttgagtggat caagacctga taatcctgaa cacgttcttg
    33481 catttctatt agaaggtcct tggtattggt aatttctcga atacttaggt taggatgagg
    33541 ctctggcttc agagctcgtt ttgtcgtaat taaacaaact tcatgccctg caaaaagcaa
    33601 agtctctgtg ataattttcc ccaagtgacc tgtagaatgg ttagtgatag agcggacgct
    33661 atcgatagct tcactggtac cgcccgatgt aactaaaatt ttcatagcac tattgtacac
    33721 aaaaataagc ggtaagtaaa atgaaagtga taaatttttg gtaaaaacga agatttacta
    33781 tagtttcaaa ctataaaacc atataaaatt taagaaagga ctctaaaagc cttaaaaaca
    33841 gagatattta cgaacgttta gagagtttta ggatgttaaa aatcttgttt tgtgatataa
    33901 tgaattatca tataagaggt tagaggaatt ttgaatgaaa acagatattg aaatcgcaca
    33961 gagtattgag ttgaagccaa ttgttgatgt tgtagagaaa cttggtattt cttatgacga
    34021 tttggagttg tacggaaagt acaaggctaa actcagcttt gataaaattc gtgcagttga
    34081 gagcaatcca gtcggtaaat tgatcttggt tactgccatc aacccaacac ctgcaggtga
    34141 aggaaagtcg acacttacca ttggtcttgc ggatgccttg aacaagattg gcaagaaaac
    34201 catgattgct atccgcgaac cgtctcttgg tccagtcatg gggatcaagg gtggtgctgc
    34261 tggtggtggg tatgcacaag ttctgccaat ggaagacatc aacctccact ttactggaga
    34321 tatgcatgct attacaactg ccaacaatgc cctttctgcc ttgattgaca accacttgca
    34381 ccaagggaat gagctggaaa ttgatcaacg tcgtatcctc tggaaacgcg ttgtggactt
    34441 gaacgaccgt gcgctccgcc atgtgactgt tggtcttggt ggtcctctaa acggtattcc
    34501 acgtgaggat ggttttgata ttacagttgc ttcagaaatc atggcaattc tttgcttggc
    34561 aacggacatc gaggacttga aacgtcgttt ggcgaatatc gttattggtt atcgctatga
    34621 ccgtacgcct gtttctgtag gtgatttgca ggttgagggt gccttggctt tgattttgaa
    34681 ggatgctatt aagccaaact tggttcagac aatttacggt acacctgcct ttgtacacgg
    34741 tggtccattt gccaatatcg ctcatggctg taactctgtt ttggcgacga caacagccct
    34801 tcacttggct gattacactg ttactgaagc tggttttggt gcggaccttg gtgctgagaa
    34861 attccttgat atcaagacac caaacttgcc aacatctcca gatgcagttg ttattgtcgc
    34921 aacccttcgt gcccttaaga tgaatggtgg tgtggctaaa gacgctctga ctgaagaaaa
    34981 tgtagaggca gttcgtgcag gttttgctaa cttgaaacgc cacgttgaaa atatccgtaa
    35041 gttcggtatt ccagcagttg tagctattaa cgaatttgta tctgatacag aagctgaaat
    35101 tgcagcctta aaagaactct gtgcctcaat cgatgtacca gttgaattgg ctagtgtctg
    35161 ggctgatgga gcagaaggtg gagtagcact tgccgaaaca gttgttaaga caattgctga
    35221 aaatccagct aactataaac gtttgtacga taatgacctt tctgtccaag aaaagattga
    35281 aaaaattgtc actgaaatct atcgtggtag caaagtgaac tttgagaaga aagctcaaac
    35341 acaaattgct caaatcgttc aaaacggttg ggacaaattg ccaatctgta tggctaaaac
    35401 tcaatacagt ttctcagaca atccaaatgc gcttggagca ccagaaaact ttgaaattac
    35461 cattcgtgaa ttggtaccaa aattaggtgc aggcttcatc gttgccttaa ctggtgatgt
    35521 tatgaccatg ccaggtcttc caaaacgtcc agcagctctc aacatggatg ttgaaagcga
    35581 tggaactgta ctaggcttgt tctagtggat tgaaattgac tttaagtgag tttggaaata
    35641 atatccaagc tcattttttc tcagactgca agcagttcat caataagatt tatactcttc
    35701 gaaaatctct tcaaac
//
LOCUS       DBEJKC010000016        35014 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.016, whole genome shotgun sequence.
ACCESSION   DBEJKC010000016 DBEJKC010000000
VERSION     DBEJKC010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 35014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.016"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..210
                     /locus_tag="ACL3G6_000799"
     CDS             <1..210
                     /locus_tag="ACL3G6_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGR0545361.1"
                     /translation="WKVRNIEAEAIRRNCERGAIFSGKIKYHEDSQFKGDHYVECYAV
                     LDNTVIARDRITVPIDPLCGKDFIE"
     gene            455..1789
                     /gene="trmFO"
                     /locus_tag="ACL3G6_000800"
     CDS             455..1789
                     /gene="trmFO"
                     /locus_tag="ACL3G6_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HGR0545362.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            1873..2610
                     /gene="pyrH"
                     /locus_tag="ACL3G6_000801"
     CDS             1873..2610
                     /gene="pyrH"
                     /locus_tag="ACL3G6_000801"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HGR0545363.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            2619..3176
                     /gene="frr"
                     /locus_tag="ACL3G6_000802"
     CDS             2619..3176
                     /gene="frr"
                     /locus_tag="ACL3G6_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HGR0545364.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3236..4090
                     /gene="cvfB"
                     /locus_tag="ACL3G6_000803"
     CDS             3236..4090
                     /gene="cvfB"
                     /locus_tag="ACL3G6_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HGR0545365.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4099..4314
                     /locus_tag="ACL3G6_000804"
     CDS             4099..4314
                     /locus_tag="ACL3G6_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HGR0545366.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDAIWQEYLEH"
     gene            4400..5368
                     /locus_tag="ACL3G6_000805"
     CDS             4400..5368
                     /locus_tag="ACL3G6_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HGR0545367.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            5561..6061
                     /locus_tag="ACL3G6_000806"
     CDS             5561..6061
                     /locus_tag="ACL3G6_000806"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0545368.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGFFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIV
                     EQSLED"
     gene            6064..6389
                     /locus_tag="ACL3G6_000807"
                     /pseudo
     CDS             6064..6389
                     /locus_tag="ACL3G6_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032802.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(6690..7801)
                     /gene="ald"
                     /locus_tag="ACL3G6_000808"
                     /pseudo
     CDS             complement(6690..7801)
                     /gene="ald"
                     /locus_tag="ACL3G6_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003018852.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0000286 - alanine dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0042853 - L-alanine catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            7978..8547
                     /locus_tag="ACL3G6_000809"
     CDS             7978..8547
                     /locus_tag="ACL3G6_000809"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0545369.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLVNPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            8615..9265
                     /locus_tag="ACL3G6_000810"
     CDS             8615..9265
                     /locus_tag="ACL3G6_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGR0545370.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     VEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            9249..11489
                     /locus_tag="ACL3G6_000811"
     CDS             9249..11489
                     /locus_tag="ACL3G6_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HGR0545371.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     LEVTKAFHVGEILVSKGSLKQKQFVVELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKAAQHGSKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGWNSW
                     KIESVR"
     gene            11631..11855
                     /locus_tag="ACL3G6_000812"
     CDS             11631..11855
                     /locus_tag="ACL3G6_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545372.1"
                     /translation="MIIGLFQSSISAVTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSW
                     SRYYSYSEYPVGSGWNYARYEVINYYTGGY"
     gene            11887..12474
                     /locus_tag="ACL3G6_000813"
     CDS             11887..12474
                     /locus_tag="ACL3G6_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0545373.1"
                     /translation="MLRLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            12478..13659
                     /locus_tag="ACL3G6_000814"
     CDS             12478..13659
                     /locus_tag="ACL3G6_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545374.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIVLALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDISSEEYQFAKNNLDVQKNLLKRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQAMYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     misc_feature    13819..13950
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            13966..14496
                     /gene="infC"
                     /locus_tag="ACL3G6_000815"
     CDS             13966..14496
                     /gene="infC"
                     /locus_tag="ACL3G6_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HGR0545375.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            14529..14729
                     /gene="rpmI"
                     /locus_tag="ACL3G6_000816"
     CDS             14529..14729
                     /gene="rpmI"
                     /locus_tag="ACL3G6_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HGR0545376.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            14781..15140
                     /gene="rplT"
                     /locus_tag="ACL3G6_000817"
     CDS             14781..15140
                     /gene="rplT"
                     /locus_tag="ACL3G6_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HGR0545377.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            15198..15578
                     /locus_tag="ACL3G6_000818"
     CDS             15198..15578
                     /locus_tag="ACL3G6_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0545378.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            15828..16628
                     /locus_tag="ACL3G6_000819"
     CDS             15828..16628
                     /locus_tag="ACL3G6_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HGR0545379.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            16591..17577
                     /locus_tag="ACL3G6_000820"
     CDS             16591..17577
                     /locus_tag="ACL3G6_000820"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HGR0545380.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGAAAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            17677..19785
                     /gene="lytB"
                     /locus_tag="ACL3G6_000821"
     CDS             17677..19785
                     /gene="lytB"
                     /locus_tag="ACL3G6_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HGR0545381.1"
                     /translation="MKKVRFIFLALLFFLASPEGAMASDGTWQGKQYLKEDGSQAANE
                     WVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGYMAKSEWVEDKGAFYYLDQD
                     GKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKADGQHAEKEWLQIKGKDYYF
                     KSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFYIKENGNYADKEWIFENGHY
                     YYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDSHSQAWYYFKSGGYMAANEW
                     IWDKESWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFYLKSDG
                     KIAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQ
                     AWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNKNAAYYQVVPVTANVYDSDGEKL
                     SYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRF
                     YHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEEL
                     DKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFF
                     GITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPY
                     WGEKIASVMMKINEKLGGKD"
     gene            complement(19846..21501)
                     /gene="pavA"
                     /locus_tag="ACL3G6_000822"
     CDS             complement(19846..21501)
                     /gene="pavA"
                     /locus_tag="ACL3G6_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HGR0545382.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            21606..22103
                     /gene="ybeY"
                     /locus_tag="ACL3G6_000823"
     CDS             21606..22103
                     /gene="ybeY"
                     /locus_tag="ACL3G6_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HGR0545383.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            22084..22479
                     /locus_tag="ACL3G6_000824"
     CDS             22084..22479
                     /locus_tag="ACL3G6_000824"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGR0545384.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENMVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            22496..23395
                     /gene="era"
                     /locus_tag="ACL3G6_000825"
     CDS             22496..23395
                     /gene="era"
                     /locus_tag="ACL3G6_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HGR0545385.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKIPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            23444..24268
                     /gene="mutM"
                     /locus_tag="ACL3G6_000826"
     CDS             23444..24268
                     /gene="mutM"
                     /locus_tag="ACL3G6_000826"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HGR0545386.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            24268..24873
                     /gene="coaE"
                     /locus_tag="ACL3G6_000827"
     CDS             24268..24873
                     /gene="coaE"
                     /locus_tag="ACL3G6_000827"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HGR0545387.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDTQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            24860..26059
                     /locus_tag="ACL3G6_000828"
     CDS             24860..26059
                     /locus_tag="ACL3G6_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HGR0545388.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            26059..26208
                     /gene="rpmG"
                     /locus_tag="ACL3G6_000829"
     CDS             26059..26208
                     /gene="rpmG"
                     /locus_tag="ACL3G6_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR0545389.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            26248..26481
                     /gene="secG"
                     /locus_tag="ACL3G6_000830"
     CDS             26248..26481
                     /gene="secG"
                     /locus_tag="ACL3G6_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HGR0545390.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            26583..28937
                     /gene="rnr"
                     /locus_tag="ACL3G6_000831"
     CDS             26583..28937
                     /gene="rnr"
                     /locus_tag="ACL3G6_000831"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HGR0545391.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     AGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYLEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRDSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            28900..29367
                     /gene="smpB"
                     /locus_tag="ACL3G6_000832"
     CDS             28900..29367
                     /gene="smpB"
                     /locus_tag="ACL3G6_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HGR0545392.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKRQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            29383..30243
                     /gene="tehB"
                     /locus_tag="ACL3G6_000833"
     CDS             29383..30243
                     /gene="tehB"
                     /locus_tag="ACL3G6_000833"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0046690 - response to tellurium ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HGR0545393.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMETVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            30316..31269
                     /gene="coiA"
                     /locus_tag="ACL3G6_000834"
     CDS             30316..31269
                     /gene="coiA"
                     /locus_tag="ACL3G6_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HGR0545394.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIQQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            31288..33090
                     /gene="pepF"
                     /locus_tag="ACL3G6_000835"
     CDS             31288..33090
                     /gene="pepF"
                     /locus_tag="ACL3G6_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGR0545395.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYNFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            33092..33805
                     /locus_tag="ACL3G6_000836"
     CDS             33092..33805
                     /locus_tag="ACL3G6_000836"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HGR0545396.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEEFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            33872..34813
                     /gene="prsA"
                     /locus_tag="ACL3G6_000837"
     CDS             33872..34813
                     /gene="prsA"
                     /locus_tag="ACL3G6_000837"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HGR0545397.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(34930..>35014)
                     /locus_tag="ACL3G6_000838"
     CDS             complement(34930..>35014)
                     /locus_tag="ACL3G6_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGR0545398.1"
                     /translation="IDYYNNKRIKVKLKGLSPVQYRTKSFR"
BASE COUNT        10538 a         6511 c         7920 g        10045 t
ORIGIN      
        1 tggaaagtaa gaaatattga agctgaggct attagaagaa attgtgagcg tggtgctatt
       61 ttttcaggta aaataaaata tcacgaagat tcacagttta aaggagatca ctatgttgaa
      121 tgttatgctg ttttagataa tacggttata gcaagagata gaataacagt ccctatcgat
      181 ccgttatgtg gaaaagattt tatagagtag catataattg attcttaact ggaatactca
      241 ctatctcttt acatcaagaa aatgactaaa cagggaagtt tgccttcttc cctttttttg
      301 ttatactagt agaagaaaaa atagaaagat ttgtgggagt gaaaaagtcc tgtggacttt
      361 ttcagcctga gccaagaaac tcgaaagctt gtaagtctga ttggcttttt caatgtgaat
      421 cttaacttca cactcccaaa gaggtattag tgtcgtgtct caatcttata tcaatgttat
      481 cggtgctggt ttggcaggtt ctgaagcagc ttaccaaatc gcagagcgtg gtattccagt
      541 taaactatat gaaatgcgtg gtgtcaagtc tacaccccag cataaaacag acaattttgc
      601 tgagttggtt tgttccaatt ctttgcgtgg ggatgctttg acaaatgcag ttggtcttct
      661 caaggaagaa atgcgtcgct tgggttctgt tatcttggaa tctgctgagg ctacacgtgt
      721 tcctgccggt ggagcccttg cggtggatcg tgatggtttc tctcaaatgg tgaccgaaaa
      781 agtggtcaac caccccttga ttgaagtggt gcgtgatgaa attacagaat tgccaacaga
      841 tgttattaca gttgtggcga ctggtccctt gactagcgat gccctggctg aaaagattca
      901 tgcccttaat aatggcgatg gcttctattt ctacgatgca gcagcgccta ttatcgatgt
      961 caacactatc gatatgagta aggtctatct caaatctcgt tatgataagg gagaagcagc
     1021 ctatctcaat gctccaatga ccaagcaaga gtttatggat ttccatgaag ccttggtcaa
     1081 tgcggaagaa gcaccgctca attcttttga aaaagaaaag tactttgaag gatgtatgcc
     1141 aatcgaagtt atggccaaac gtggcattaa aactatgctt tatggcccta tgaagccagt
     1201 cggtcttgag tatccggacg actacacagg acctcgtgat ggagaattta aaacacctta
     1261 tgcggttgtg caacttcgtc aggataatgc agctggtagc ctatacaata ttgttggttt
     1321 ccagacccac ctcaaatggg gagaacaaaa gcgtgtcttc caaatgattc cgggtcttga
     1381 aaatgcggag tttgtccgtt atggtgtcat gcatcgcaat tcttacatgg attcaccaaa
     1441 tcttcttgag cagacttacc gttccaagaa acaaccaaat ctcttctttg ctggtcagat
     1501 gacgggggtg gaaggctatg ttgagtcggc ggcttcgggc ttagttgcgg gaattaacgc
     1561 agctcgtctc ttcaaggaag aaagcgaggt tattttcccc gagacgacag cgattggaag
     1621 cttagctcat tacattaccc atgccgacag caaacatttc caaccaatga atgtcaattt
     1681 tgggatcatc aaggagttgg aaggcgagcg tatccgtgat aagaaggctc gttatgaaaa
     1741 aattgcagag cgtgcccttg ccgacttaga ggaatttttg actgtctaat ttttttgaaa
     1801 gaattgttca tgatactata aaaatcttag aaattgtgat aaaataggta ggatgaaaga
     1861 aggagagtga aaatggcgaa tcccaagtat aaacgtattt taatcaagtt atcaggtgaa
     1921 gcccttgccg gtgaacgtgg cgtagggatt gatatccaaa cagttcaaac aatcgcaaaa
     1981 gagattcaag aagttcatag cttaggtatc gaaattgccc ttgttattgg tggaggaaat
     2041 ctctggcgtg gagaacctgc agcagaagca ggtatggacc gtgttcaggc agattacact
     2101 ggaatgcttg ggactgttat gaatgctctt gtgatggcag attcattgca acaagttggg
     2161 gttgatacgc gtgtacaaac agctattgct atgcaacaag tggcagagcc ttatgtccgt
     2221 ggacgtgccc ttcgtcacct tgaaaaaggc cgtatcgtta tctttggtgc tggaattggt
     2281 tcaccatact tctcgacaga tacaacagcg gcccttcgtg cagctgaaat cgaagcagat
     2341 gccatcctca tggctaaaaa tggcgtcgat ggtgtgtaca atgccgatcc taagaaggac
     2401 aagacagccg ttaagtttga agaattgacc caccgtgatg ttatcaacaa aggtcttcgt
     2461 atcatggact caacagcctc aaccctctca atggacaacg acattgactt ggttgtcttc
     2521 aacatgaacc aatcaggcaa catcaaacgt gtcgtatttg gtgaaaatat cggaacaaca
     2581 gtttcaaata atatcgaaga aaaggaataa gaaagaatat ggctaacgta attattgaaa
     2641 aagctaaaga gagaatgacc cagtctcacc aatcacttgc tcgtgaattt ggtggtatcc
     2701 gtgctggtcg tgccaatgca agcttgcttg accgtgtaca tgtagaatac tatggagtcg
     2761 aaactcctct taaccaaatc gcttcaatta cgattccaga agcgcgtgtt ttgttggtaa
     2821 caccatttga caagtcttca ttgaaagaca tcgaacgtgc cttgaacgct tctgatcttg
     2881 gtatcacacc ggctaatgac ggttctgtga ttcgcttggt tatcccagct cttacagaag
     2941 aaactcgtcg tgaccttgct aaagaagtga agaaggtcgg cgaaaatgct aaagtggctg
     3001 tccgcaatat ccgtcgcgat gctatggacg aagctaagaa acaagaaaaa gcaaaagaaa
     3061 tcactgaaga cgaattgaag actcttgaaa aagacattca aaaagtaaca gacgatgctg
     3121 ttaaacacat cgacgacatg actgctaaca aagagaaaga acttttggaa gtctaaaaat
     3181 aaacagaaaa actcagttgg cattgctggc tgagttttat tcgaaagaag gaaatatgaa
     3241 tacaaatctt gcaagtttta tcgttggact gatcatcgat gaaaacgacc gtttttactt
     3301 tgtgcaaaag gatggtcaaa cctatgctct tgctaaggaa gaaggccaac atacagtagg
     3361 ggatacggtc aagggttttg catacacgga tatgaagcaa aaactccgcc tgacaacctt
     3421 agaagtgact gccactcagg accaatttgg ttggggacgt gtcacagagg ttcgtaagga
     3481 cttgggtgtc tttgtggata caggccttcc tgacaaggaa atcgttgtgt cactcgatat
     3541 tctccctgag ctcaaggaac tctggcctaa gaagggcgac caactctaca tccgtcttga
     3601 agtggataag aaagaccgta tctggggcct cttggcttat caagaagact tccaacgtct
     3661 tgctcgtcct gcctacaaca acatgcagaa ccaaaactgg ccagccattg tttaccgtct
     3721 caagctgtca ggaacttttg tttacctacc agaaaataat atgcttggtt ttattcatcc
     3781 tagcgagcgt tacgcagagc cacgtttggg gcaagtatta gatgcgcgcg ttattggttt
     3841 ccgtgaagtg gaccgcactc tgaacctctc cctcaaacca cgctcctttg aaatgttgga
     3901 aaacgatgct cagatgattt tgacttattt ggaaagtaat ggcggtttca tgaccttaaa
     3961 tgataagtca tctccagacg acatcaaggc aacctttggc atttctaaag gtcagttcaa
     4021 gaaagcctta ggtggtctta tgaaggctgg taaaatcaag caggaccagt ttgggacaga
     4081 gttgatttag ggaggcttat gagaaaatca ttttacactt ggctcatgac cgagcgcaat
     4141 cctaaaagta acagtcccaa agcaattttg gcagacctcg cttttgaaga ggcagctttt
     4201 ccaaaacaca cagatgattt tgatgaggtc agtcgctttt tggaggagca tgccagtttc
     4261 tcttttaacc taggagactt tgacgctatc tggcaagaat acttagaaca ctagcattta
     4321 ttcactaggt ttgggctagt aatttctcca tccctctgct ataataaaaa gaaataaaag
     4381 gattagagag gttctttatt tgaaggaaca ttcaatagac attcaactga gtcatccaga
     4441 tgacctgttt catctttttg gttccaatga acgccatctt cgtttgatgg aagaagagct
     4501 tgatgttgtg attcatgctc gtacggagat tgtccaggtt ttgggagaag agtctgcttg
     4561 cgaggaagcc cgtcaggtta ttcaagctct catggtcttg gtaaatcgtg ggatgaccgt
     4621 tggtacgcca gatgtagtga cggctattag tatggtcaaa aatgatgaaa ttgacaagtt
     4681 tgtcgccctt tacgaagaag aaatcatcaa ggataatact gggaagccta tccgcgtcaa
     4741 aaccttaggt caaaaacttt atgtggacag tgtcaaacag catgatgtga cctttggaat
     4801 tgggccagca ggtacaggga agaccttcct tgcagtgacc ttggcagtga ctgcccttaa
     4861 acgtgggcaa gtcaagcgaa ttatcctaac tcgtccagcg gtggaagcgg gagagagtct
     4921 tggatttctt ccgggtgatc ttaaggagaa ggtggatcct taccttcgtc ctgtttacga
     4981 tgccttgtat caaattcttg ggaaagacca aacgactcgt ctcatggagc gtgaaattat
     5041 cgaaattgcg ccccttgcct atatgcgtgg ccggaccttg gatgatgcct ttgtcattct
     5101 cgatgaggcg caaaacacga ccatcatgca gatgaagatg ttcttgacgc gtttaggctt
     5161 tcattctaag atgattgtca atggagatat cagtcagatt gacctgccac gtaatgtcaa
     5221 gtccggtttg attgatgctc aagagaaact caagaacatc catcagattg actttgttca
     5281 tttttcagcc aaggatgtgg ttcgccatcc agttgtcgct cagattatcc gagcctatga
     5341 atattctact gaagttgcac acgactgatt ttgaggaagt tcgcctgcaa aagaatatac
     5401 ttttgagaga ggaaaatcca gttgtatagg ctaaaggttt tatccaaagg tctgagacaa
     5461 cgattaggca cgatggaaag aacttttatg tgactgatga cgatcagtgc atcttcctgt
     5521 gtcataatca cagggcacaa gaaagtagga atttgaaaag atgattgacc aactatctaa
     5581 gtattacagt tgtaggatac taactgaaaa ggatattcca agtattttat ctttatatga
     5641 aagtaatcct ctgtattttc agcattgtcc accagagcca aattttgcaa ctgtaaaaga
     5701 ggacatgctt tgtctacctg aaggtaaagc taaggctgat aagttttttg ttggattttg
     5761 gaatggatct gaccttgtgg ctgttatgga ttttgtctat gcatatcctg atgaggagac
     5821 tgtttttatt ggttttttta tggttgatca agcctatcag aggaaaggga ttggtagtca
     5881 tattgtgaca gaagcactag cttattttgc taagaacttt cgaaaggcac gtttggctta
     5941 tgttaaggga aatccgcaat ctcagcattt ttgggaaaag cagggcttta aatcaattgg
     6001 atgcgaggtt aagcaagaac tctatacggt tgttatcgtt gaacagagcc tagaagatta
     6061 gaaatggcat caagtaagaa ctatttggaa tttgttttgg aacaattatc aggattagat
     6121 gatgtgactt accgttccat gatgggggag tatattcttt acttccgcgg caagattatt
     6181 ggcggcattt atgacgatcg cttttagtta aacccgtgca agcagtctta gataagattg
     6241 accaatcttc ttttgagttt ccatacaaag gtgccaaaga aatgatttga gtggaagaac
     6301 ttgataataa gatgtttcta taagacctga ttttagctat gtataaccaa ctgccaacgc
     6361 ccaaacctaa aaagaaaaag caagggtgaa cgaagtaaaa aagaagtctg ctaaggccct
     6421 gtctttgcac gggtaaaatt ttatatataa aaagaagctg ggactaaaga gctcagcttc
     6481 ctttggttta tataattgtc attacaagac gaagtggttg ggcgaaactc tgttgacttt
     6541 attcaattta gagtttctta tgcacaattg agtctggaac gaaagtctcc agttgcaaag
     6601 tatacagtac aataaaccaa cgatgtaata gctgatgaca caaagcacag tgggtaggac
     6661 ttgcgaagtc acccttttct tttcaaaatt tatactaaat cattgatatc agtgtagtca
     6721 cgattaagtc cttgagcaac tggtaggcta gtcaagtaac cttgataagt ggtcacacct
     6781 tgacgcaagc cttcatcttc agagattgct tgtgcgaatc ctttgccagc caaagcttcg
     6841 atataaggaa gagtgacatt ggttagggcg atggttgaag tgcgagcaac cgcaccaggg
     6901 atattggcaa cggcatagtg gagaacaccg tgtttttcat agacgggttc atcgtgcgtt
     6961 gtcacacggt cagctgtttc gataacgcca ccttggtcaa cagcaacgtc aacgatacag
     7021 agcctggacg catttgtttg accatctcat ctgtcaccaa ttccggtgct tttgcaccag
     7081 ggatgagaat ggctccaatc accacatcag catctctcat acttgcttca atgttgaatg
     7141 aattagatat aagagtttga atttgacttc caaagacttc ttctagaact gagagacgct
     7201 tggcactaat atctaaaata gtcacttgag caccaagacc aagggcgatg cgggcagcat
     7261 gtgtaccgac gacaccatca ccgatgatag ttacttttcc ttttggaaca cctggtacac
     7321 caccaggtag aacaccagag ccaccagctt gcttagtaag gaagtgagct ccgatttaaa
     7381 cagccatacg acctgcaacc tcactcatag gaacgaggag cggtagttgt ccttgattgt
     7441 cacgaacagt ttcataggca attcctgttg tttttgctgc taacatagca tctgctaatt
     7501 ctggagcagc ggccatgtgc aagtaggtga agagaagaag aacgtcgcgc aagtaaccgt
     7561 attcagaact taaaggttct tttactttca caaccaactc tgctgcccaa gcttcaccag
     7621 cagtagcgac aatctcagct ccttgctttt gatagtcagc atcagtaaag ccagaaccga
     7681 gaccagcatt tgtttcgata aggacacgat gaccacgact aactaagcta tgaacacctg
     7741 caggtgtgag ggcgacacgg ttttcgttat ttttaatttc ttttgggatt ccgattaaca
     7801 ttgagataac ctacctttca attgacggtc ttgttttggt tgtcacattc cagttcataa
     7861 atcaaaaatg tgacggtttc attgtatatg aaaccgcttc aaaaatcaag aaaaacttgt
     7921 catcccaatt tttttatgct agactagtga aaatcaagct ctaatggagg gaaaagtatg
     7981 gaatcaattt ttgtaaaact tgcccagtat ccgtctatag aaacggagcg tttattgctt
     8041 agacctgtaa ctttggatga tgcggaagca atgtttgact atgcctcgga caagggtaat
     8101 acacgttaca cttttccaac caatcaaagc ttggaagaaa ccaagaataa cattgctcag
     8161 ttctatttgg ttaatccctt gggacgttgg ggaatagaac taaaaagcaa tggtcagttt
     8221 attggaacca ttgacttgca caagattgat tctgttctta agaaggcagc tattggctac
     8281 attatcaata aaaagtattg gaatcaagga ttaacgacag aagccaatcg tgctgtgatt
     8341 gagctagctt ttgagaagat agggatgaat aagttgactg cccttcacga taaggctaat
     8401 cccgcgtcag gaaaggtcat ggagaaatca ggcatgcgtt tttcccatgc agaaccatat
     8461 gcttgtatgg accagcatga aaaaggccga atcgtgacaa gagttcatta tgtcttgacc
     8521 aaggaagact attttgcaaa taaataagca gttgaaaaga aatttttcga ctgttttttc
     8581 ttcctcttac gaataatcta agagaggaga aaatatggaa gcaattatcg agaaaatcaa
     8641 agagtataaa atcatcgtca tctgtactgg tctgggcttg cttgtaggcg gatttttcct
     8701 gctaaagcca gctccacaaa cacctgtcaa agaaacgaat ttgcaggttg aagttgcagc
     8761 tgtttccaag gatttggtat ccgaaaagga agtgaacaag gaagagaagg aagaaccagt
     8821 tgaacaagat ctaatcacag tagatgtcaa aggtgctgtc aaatcgccag ggatttatga
     8881 cttgcctgta ggtagtcgag tcaatgatgc tgttcagaag gctggtggct tgacagagca
     8941 agcagacagc aagtcgctca atctagctca gaaagttagt gatgaggctc tggtttacgt
     9001 tcctactaag ggagaagaag cagttagtca acagactggt tcggggacag cttcttcaac
     9061 aagcaaggaa aagaaggtca atctcaacaa ggccagtctg gaagaactca agcaggtcaa
     9121 gggactggga ggaaaacgag ctcaggacat tatcgaccat cgtgaggcaa atggcaagtt
     9181 caagtcagta gacgagctca agaaggtctc tggcattggt ggcaaaacaa tagaaaagct
     9241 taaagactat gttacagtgg attaagaatt tctctattcc cctaatttac ctgagttttc
     9301 tattactttg gctttattac gctattttct cagcatctta tcttgctttg ttgggctttg
     9361 tttttctgct agtctgtctc tttatccaat ttccgtggaa atctgctggt aaagttctaa
     9421 taatttgcgg aatctttgga ttttggtttg tttttcaaaa ttggcaacag agtcaagcga
     9481 gtcaaaatct ggcggattct gttgaaaggg tacggatttt gcctgatact attaaggtta
     9541 atggtgatag tctatccttt cgtggcaagt ctaacggtcg tgctttccaa gtctattata
     9601 aactccagtc cgaggaggag aaagaagcct ttcaagcttt aaccgacctg catgagatag
     9661 gactagaagg gaagctttcg gagccagaag ggcagagaaa ttttggtggc tttaattacc
     9721 aagcctatct gaagactcag ggaatttacc agactctcaa tatcaaaaca atccagtcac
     9781 ttcaaaagat tggcagttgg gatataggag aaaacttgtc cagtttacgt cgaaaggctg
     9841 tggtttggat taagacgcac tttccagacc ctatgcgcaa ttacatgaca ggactcttgc
     9901 tgggacatct ggacaccgac tttgaggaga tgaatgagct ttattccagt ctaggaatta
     9961 tccacctctt tgctctatct ggtatgcagg taggtttttt catgaatgga tttaagaaac
    10021 ttctcttgcg attgggcttg acccaagaaa agttgaaatg gctgacttat cccttttccc
    10081 ttatctatgc gggactaact ggcttttcag catcggttat tcgcagtctc ttgcaaaagc
    10141 tactggctca acatggggtt aagggcttgg ataattttgc cttgacggtg cttgtcctct
    10201 ttattgtcat gccaaacttt ttcttgacag caggaggagt cttgtcctgc gcttatgctt
    10261 ttatcctgac catgaccagc aaagaagggg aggggctcaa ggctgttact agtgaaagtc
    10321 tagtcatctc cttgggcata ttgcccattc tatccttcta ttttgcggaa tttcaacctt
    10381 ggtctatcct tttgaccttt gtcttttcct ttctatttga cttgaccttc ttaccgctct
    10441 tgtctatttt atttgtcctt tcctttctct atccagtcat tcagctgaac tttatctttg
    10501 aatggttgga gggcattatt cgcttggtgt cacaggtgac aagtagacct ctggtctttg
    10561 gacaacccaa tgcatggttt ttaatcctat tgttaatttc cttggctttg gtctatgatt
    10621 tgagaaaaaa cattaaaaag ctaacggtat tgtgcttatt gattacaggg ctctttctcc
    10681 tgaccaagca tccactggaa aatgaaatca ccatgctgga tgtggggcaa ggagaaagta
    10741 ttttcctacg ggatgtaact gggaaaacca ttctcataga tgtaggtggt aaggcagaat
    10801 cttataagaa aatcgaaaaa tggcaagaaa agatgacgac cagcaatgca cagagaagct
    10861 tgatacccta tcttaaaagt cgaggagtag ctaagattga ccagctgatt ttgacaaata
    10921 cggacaagga acatgtcgga gatttgttag aggtgaccaa ggctttccat gtaggggaga
    10981 ttttagtatc aaaaggcagt ttgaagcaga agcaatttgt ggtagaacta caggcgactc
    11041 aaacaaaggt gcgtagtatg acagtagggg agaacttgcc catttttgga agtcagttag
    11101 aagttctatc tccaaggaaa atgggagatg gaggacacga tgatacccta gttctgtatg
    11161 ggaaattctt ggataagcaa tttctcttca cgggaaattt ggaggagaaa ggagagaagg
    11221 acttgctgaa gcactatcca gacttgaaag taaatgtttt gaaagctgcc caacatggct
    11281 ctaaaaagtc atcaagtcca gcctttctag aaaaactcaa accagagctt actcttatct
    11341 cagttggaaa gagcaatcga atgaaactcc cccatcagga aacattgaca cgactggaag
    11401 gtatcaatag caaagtttac cgaactgacc agcaaggagc tatacggttt aaaggttgga
    11461 atagttggaa aatcgaaagt gttcgatagg aaggataaat gttgtagatt agtgaaataa
    11521 actaaaaatt tgttgcataa taatgataaa aatggtataa tgaaaatgta ttcaatactg
    11581 aggatataaa atcattaaaa attagcaaaa atcgtttaat tagttagttt atgattattg
    11641 gtctttttca gtccagtata tctgctgtga cagtcactaa aagttacaag tatgattgga
    11701 atacggtttg ggaatatagt accaactatc acgaccatca gtatgcttgg attccgtcat
    11761 ggtctcgtta ttacagctat tctgagtatc cagttggttc tggctggaac tacgctcgtt
    11821 atgaggtcat aaactactat actggaggtt attaatcctt aaagagtgag aaaaggaggg
    11881 ctggatatgt taaggcttac tcatgttacc ctaaaaacgc gacaagtcat cttgcaagat
    11941 gtggatttca cctttaaaaa gggtagggtt tatggtcttc ttgctatcaa tggctctgga
    12001 aagacgaccc tgttccgtgc cattagcaat ttaattccca taagtagtgg aaatatcgca
    12061 gcccctcctt ctttatttta ttatgagagt attgaatggc tggatggaaa cttaagtggg
    12121 atggactacc ttcgtcttat caaaaacatc tggaagtcag gtctgaactt gagggatgaa
    12181 atcgcctatt gggaaatgtc tgactatatc agtcttccca ttcgcaagta ttccttaggc
    12241 atgaagcaac gcttggtgat tgccatgtat ttcctcagtc aggccaaatg ctggctcatg
    12301 gatgagatta caaatggctt agatgagtat tatcgacaga agttttttga taggctagca
    12361 caaatcgata gacaagaaca gctggttctt ttaagttccc actataagga agagttggtt
    12421 gatgtctgcg atagagtagt aaccattcat caggggcaga tagaagaggt ttagtttatg
    12481 aaagatgtta gtctattttt attgaaaaaa gttttcaaaa gccgcttaaa ctggattgtc
    12541 ttagctttat ttgtatctgt actcggtgtt accttttatt taaatagtca gactgcaaac
    12601 tcacacagct tggagagcag gttggaaagt cgcattgcag ccaacgagag ggctatcaat
    12661 gaaaatgaag agaaactctc ccaaatgtct gatatcagct cggaggaata ccagtttgct
    12721 aaaaataatt tagacgtgca aaaaaatctt ttgaagcgaa agacagaaat tctgacttta
    12781 ttaaaagaag ggcgctggaa agaggcctac tatctgcagt ggcaagatga agagaagaat
    12841 tatgaatttg tatcaaatga cccgactgct agctctggct taaaaatggg ggttgaccgc
    12901 gaacggaaga tttaccaagc catgtatccc ttgaacataa aagcacatac tttggagttt
    12961 ccgacccacg ggattgatca gattgtctgg attttagagg ttatcatccc aagcttgttt
    13021 gtggttgcga ttatttttat gctaacacaa ctatttgcag aaagatatca aaatcatctg
    13081 gacacagctc acttatatcc tgtttcaaaa gtgacatttg caatatcctc tcttggagtt
    13141 ggagtgggat atgtaactgt gctgtttatc ggaatctgtg gcttttcttt tctagtggga
    13201 agtctgataa gtggttttgg acagttagat tatccctacc caatttatag cttagtgaat
    13261 caagaagtaa ctattgggaa aatacaagat gtattatttc ctggcttgct cttagctttc
    13321 ttagccttta tcgtcattgt ggaagttgtg tacttgattg cttacttttt caagcaaaaa
    13381 atgcctgtcc tctttctttc actcattggg attgttggct tattgtttgg catccaaacc
    13441 attcagcctc ttcaaaggat tgcacatctg attcccttta cttacttgcg ttcagtggag
    13501 attttatctg gaagattatc taagcagatt gataatgtcg atctaaattg gagcatgggg
    13561 atggtcttac ttccttgcct gattatcctt ttgttagtgg ggattctatt tatcgaaaga
    13621 tggggaagtt cacgtaaaaa ggaagttttt aaagtttagt tttcctatag ggaagctaaa
    13681 gaaaaactaa catagggaga gaatcaactt ggttctctct ttttgattcg aaaaccaaac
    13741 caaaatacaa acacaaactt ttcaaaaaat aactttttat cttgacaaga gctagaaaac
    13801 ttggtatcat ataaaagttg agaaaagcag aagtgagagc ttctcgcctt gtgacattaa
    13861 gttgcctggc cctacggatg aaaagtttcg aagaaacgct atcataacgt gcgggcttgt
    13921 atatttacga gtccgctatt gtttttctct aataaaacaa aagaggtgaa aaccatagca
    13981 aagcaagact tattcatcaa tgatgagatt cgtgtacgtg aagttcgctt gattggtctt
    14041 gagggagaac agctaggcat caagccactc agtgaagcgc aagctttggc tgataacgct
    14101 aatgttgacc tagtattgat tcaaccccaa gccaaaccgc ctgttgcaaa aattatggac
    14161 tacggtaagt tcaaatttga gtaccagaag aagcaaaaag aacaacgtaa aaaacaaagc
    14221 gttgttactg tgaaagaagt tcgtctaagt ccaacaattg acaagggtga ctttgataca
    14281 aaacttcgca atgcacgtaa gttccttgaa aaaggaaata aagttaaggt atctattcgc
    14341 tttaagggtc gtatgattac ccacaaagag attggtgcaa aagttttagc cgagtttgct
    14401 gaagcaactc aagatattgc catcatcgaa caacgtgcta aaatggatgg acgtcaaatg
    14461 ttcatgcaat tggcgccagc gactgacaaa aaataattgt cagaaagtta aataaaggag
    14521 aaaaaatcat gccaaaacaa aaaacacacc gcgcatcagc taaacgtttc aaacgtacag
    14581 gttctggtgg acttaaacgt ttccgtgctt acacttctca ccgtttccac ggaaaaacta
    14641 agaaacaacg tcgtcatctt cgtaaagcat ctatggtgca ttcaggagat tacaaacgta
    14701 tcaaagcaat gcttactcgc ttgaaataat agcttgactg taagtaaaca attctaggaa
    14761 atatttggag gaaataaaac atggcacgtg ttaaaggtgg cgttgtatca cgcaaacgtc
    14821 gtaaacgtat tcttaaatta gcaaaaggtt actatggagc taaacacatc ttgttccgta
    14881 ctgcaaaaga acaagtaatg aactcttact actatgcata ccgtgaccgt cgtcagaaaa
    14941 aacgtgactt ccgcaaattg tggattactc gtatcaatgc ggcagctcgt atgaacggac
    15001 tttcatactc acaattgatg catggtttga aattggctga gattgaagtt aaccgtaaaa
    15061 tgcttgctga cttggctgtt aacgatgcag tagctttcac agctcttgca gatgcagcta
    15121 aagcaaaact tggtaaataa caactgatga gactggaaca ggattgtcca gtctttttaa
    15181 aaataaagga gaaagatatg gcttcaaaaa tgctacacac ttgcttacga gtagaaaatc
    15241 ttgaaaaatc aatcgcattt tatcaagatg cttttggttt taaagaattg cgtcgcagag
    15301 attttccaga ccatgccttc acgattgtct atctaggtct tgagggtgat gattatgagt
    15361 tggagttgac ttataactac gatcacggtc cgtatgtggt tggtgatggg tttgcccata
    15421 tcgccctcag tacacctgat cttgaggcac ttcatcaaga acacagtgca aaaggctatg
    15481 aagtgactga gccaaatggt ctaccaggaa ctacaccaaa ctattacttt gtcaaagacc
    15541 ctgatggata taaggtcgaa gtcattcgtg aaaaataatt tcgtgcaagt taagtagaat
    15601 attcgttttc tacttgactt tttttagctg aaagagtata ctaataaaaa ttcaaccttt
    15661 aaggggagtc cagagagact cacaaggtgt cagataaaag aatagtgcaa ttttctagag
    15721 gagacctttt gagtgtgctc tcttgtgttg tacgatttta actgaggcct tgcactagca
    15781 aggtcttttc tttatctggt ccccttaaaa tttaaggagg aaaagttatg aatctcacat
    15841 gtaagaagcg tttgggtgtc attcggttgg aaaccatgaa ggtggttgca caagaggaaa
    15901 tcgcgccagc aatctttgaa ttagtcctag aaggagaaat ggttgaagcc atgcgagcag
    15961 gccaatttct tcatctgcgt gtaccagacg atgcccatct cttacgtcgt cctatttcaa
    16021 tttcgtctat tgacaaggca aacaagcagt gtcacctcat ttatcggatt gagggagctg
    16081 ggactgcaat tttttcaacc ttaagtcagg gagacactct tgatgtgatg gggcctcagg
    16141 gaaatggttt tgacttgtct gaccttgatg agcagaatca ggttctcctt gttggtggtg
    16201 ggattggtgt tccacccttg cttgaggtgg ccaaggaatt gcatgaacgt ggagtgaaag
    16261 tagtgacagt cctcggtttt gctaataagg atgctgttat tttgaaaacg gaattggctc
    16321 agtatggtca ggtctttgta acgacagatg atggttctta tggcatcaag ggaaatgttt
    16381 ccgttgttat caatgattta gatagtcagt ttgatgctgt ttactcgtgt ggggctccag
    16441 gaatgatgaa gtatatcaat caaacctttg atgatcaccc aagagcctat ttatctctgg
    16501 aatctcgtat ggcttgtggg atgggagctt gctatgcctg tgttctaaaa gtaccagaaa
    16561 gcgagacggt cagccaacgc gtctgtgaag atggtcctgt tttccgcaca ggaacagttg
    16621 tattataagg agaaaattat gactacaaat cgattacaag tgtctctacc tggtttggat
    16681 ttgaaaaatc cgattattcc agcatcaggc tgttttggct ttggacaaga gtatgccaag
    16741 tactatgatt taaacctttt aggttctatt atgatcaagg cgacaaccct tgaaccacgt
    16801 tttgggaacc caactccaag agtagcagag acgcctgctg gtatgctcaa tgcaattggc
    16861 ttgcaaaatc ctggtttaga ggttgttttg gctgaaaagc taccttggct ggaaagagaa
    16921 tatccaaatc ttcctattat tgccaatgta gctggttttt caaaacaaga gtatgcagct
    16981 gtttctcatg ggatttccaa ggcaactaat gtaaaagcta tcgagctcaa tatttcttgt
    17041 cccaatgttg accactgtaa tcatggactt ttgattggtc aagatccaga tttggcttat
    17101 gatgtggtga aagcagctgt ggaagcctca gaagtgccag tttatgtcaa attaaccccg
    17161 agtgtgaccg atatcgttac tgtcgcaaaa gctgcagaag atgcgggagc aagtggcttg
    17221 accatgatca atactctggt tggaatgcgc tttgacctca aaaccagaaa accaatcttg
    17281 gccaatggaa caggtggaat gtcaggtcca gcagtctttc cagtagccct caaactcatc
    17341 cgccaagtag cccaaacaac agacctgcct atcattggaa tggggggagt ggattcggct
    17401 gaagctgccc tagaaatgta tctggctggg gcagctgcta tcggagttgg aacagctaac
    17461 tttaccaatc cttatgcctg ccctgacatc atcgaaaatt taccaaaagt catggataaa
    17521 tacggtatta gcagtctgga agaactccgt caggaagtaa aagagtctct gaggtaaact
    17581 gcaatcaatc tgttcttgat tttttattag tttgtaatat gaatttagga gaattttggt
    17641 acaataaata taaataagaa cagaggaaga aggttaatga agaaagtaag atttattttt
    17701 ttagctctgc tatttttctt agctagtcca gagggtgcaa tggctagtga tggtacttgg
    17761 caaggaaaac agtatctgaa agaagatggc agtcaagcag cgaatgagtg ggtttttgat
    17821 actcattatc aatcttggtt ctatataaaa gcagatgcta actatgctga aaatgagtgg
    17881 ctaaagcaag gtgacgacta tttttacctc aaatctggtg gctatatggc caaatcagaa
    17941 tgggtagaag acaagggagc cttttattat cttgaccaag atggaaagat gaaaagaaat
    18001 gcttgggtag gaacttccta tgttggtgca acaggtgcca aagtaataga agactgggtc
    18061 tatgattctc aatacgatgc ttggttttat atcaaagcag atggacagca cgcagagaaa
    18121 gaatggctcc aaattaaagg gaaggactat tatttcaaat ccggtggtta tctactgaca
    18181 agtcagtgga ttaatcaagc ttatgtgaat gctagtggtg ccaaagtaca gcaaggttgg
    18241 ctttttgaca aacaatacca atcttggttt tacatcaaag aaaatggaaa ctatgctgat
    18301 aaagaatgga ttttcgagaa tggtcactat tattatctaa aatccggtgg ctacatggca
    18361 gccaatgaat ggatttggga taaggaatct tggttttatc tcaaatttga tgggaaaata
    18421 gctgaaaaag aatgggtcta cgattctcat agtcaagctt ggtactactt caaatccggt
    18481 ggctacatgg cagccaatga atggatttgg gataaggaat cttggtttta cctcaagttt
    18541 gatggcaaaa tggctgaaaa agaatgggtc tacgattctc atagtcaagc ctggtactac
    18601 ttcaaatccg gtggttacat gacagccaat gaatggattt gggataagga atcttggttt
    18661 tatctcaaat ctgatgggaa aatagctgaa aaagaatggg tctacgattc tcatagtcaa
    18721 gcttggtact acttcaaatc cggtggttac atgacagcca atgaatggat ttgggataag
    18781 gaatcttggt tttacctcaa gtctgatggc aaaatggctg aaaaagaatg ggtctacgat
    18841 tctcatagtc aagcctggta ctacttcaaa tctggtggct acatggcgaa aaatgagaca
    18901 gtagatggtt atcagcttgg aagcgatggt aaatggcttg gaggaaaagc tacaaataaa
    18961 aatgctgctt actatcaagt agtgcctgtc acagccaatg tttatgattc agatggtgaa
    19021 aagctttcct atatatcgca aggtagtgtc gtatggctag ataaggatag aaaaagtgat
    19081 gacaagcgct tggctattac tatttctggt ttgtcaggct atatgaaaac agaagattta
    19141 caagcgctag atgctagtaa ggactttatc ccttattatg agagtgatgg ccaccgtttt
    19201 tatcactatg tggctcagaa tgctagtatc ccagtagctt ctcatctttc tgatatggaa
    19261 gtaggcaaga aatattattc ggcagatggc ctgcattttg atggttttaa gcttgagaat
    19321 cccttccttt tcaaagattt aacagaggct acaaactaca gtgctgaaga attggataag
    19381 gtatttagtt tgctaaacat taataatagc cttttggaga acaagggcgc tacttttaag
    19441 gaagccgaag aacattacca tatcaatgcc ctttatctcc ttgcccatag tgccctagaa
    19501 agtaactggg gaagaagtaa aattgccaaa gataagaata atttctttgg cattacagcc
    19561 tatgatacga ccccttacct ttctgccaag acatttgatg atgtggataa gggaatttta
    19621 ggtgcaacca agtggattaa ggaaaattat atcgataggg gaagaacttt ccttggaaac
    19681 aaggcttctg gtatgaatgt ggaatatgct tcagaccctt attggggcga aaaaattgct
    19741 agtgtgatga tgaaaatcaa tgagaagcta ggtggcaaag attagtacta taagtgaata
    19801 tgatttgagt gaatagtaag ttaaaaatcc tgatttcaag taaaatcagg attttttcat
    19861 ggatgcaatt tttttggagt ctggtgtgac gcggagggtc ttttgtcctg tgtaagtgac
    19921 aaagccgggt tttccaccag ttggtttatt gagttttttg acttcaatca tatctacctg
    19981 caccagattc gacaggcgcc cttgagagaa gtaggcagct aactctgctg cgtctgtctt
    20041 gactgcatca gatgggtcaa gatttcctga gatgacaaca tggcttccag gaatgtcctt
    20101 agcatggaac caaagttcct ccttgcgggc cattttaaag gtcaattcct cattttgaag
    20161 attgtttcgt ccgacataga tgatggtttt gccatcgctt gctagatatt gttctagttt
    20221 tttgcgtttc tggattttct cccgttgtct tctgcggata aaacctgttt gaatcaattc
    20281 ttcacggatt tcagcgattt cttccagtcc agcttggttg aggacggttt ctacactttc
    20341 cagatagaga atagtggctt tggtttcttc aatcaaatca gtcaagtatt tgacagcttc
    20401 tttgagtttc tgataccgtt taaaatagcg ttgggcattc tggttgggag tcagagcctt
    20461 atcaagcgca atcatgatag gttggttggt atagtagttg tctaggataa cctggtcttg
    20521 gtcgttaggc acttggtgta ggaaggttgt cagcaattct cctttttgac gaaattcttc
    20581 agcgttgtct gtcgccagta actctttttc ctgttttttg agtttgtgtc ggtttttctg
    20641 aagttcattt tcaacacgac gaatcagttc actggcctgc tgtttgacgc ggtcgcgctc
    20701 agccttatcc ttatagtagg tgtccaacaa atcagaaaga tttgcaaaag gctctcccac
    20761 ctgatttgca aaaggaactg gactgaagga agtctcagtc aagcatggct tggtttcttg
    20821 attgaaaaaa tttcggaaag cggaaagttt ttcactaacc agtatccttt ccaattcatt
    20881 tgcagtatcg cgtcccagac cttgaaagag gctttgaaga ttttttgctg ttagttcttg
    20941 ggtttgcagg atttcaaaga gcttttcatc tttgatagta aaaggattga gagattctgt
    21001 acttggcgga gcgatatagg tcgatcctgg aagtaaggtg cggtagctat tttgtgaaaa
    21061 accgacgtgt ttgataactt cgaggatttt atgactgctt ttatcgacca gtagaatatt
    21121 actgtgtttc cccataattt caataatcaa ggtagcctgg atatggtctc caatctcgtt
    21181 tttattggaa actgtcattt ccacaatacg gtcattttcc acttgctcaa tcgactcaat
    21241 cagggccccc tgcaaatact ttctcaaaac catgataaag gtagaaggtt gggctggatt
    21301 ttcaaaagtc gtttgggtca gctgaatgcg tccaaaaact ggatgggcag aaaggagcag
    21361 gcgatggctt tggcgattgc tgcggatttg caagaccaac tcttgttcaa aaggctgatt
    21421 gattttctgg atgcgaccat tcactaattc gcttcgcaat tcctcaacta tgtggtgtaa
    21481 aaaaaatcca tcaaatgaca tcgttctctc cttgtgattg tattccatag tattatatca
    21541 aaaaggtaga ataaaatcat ggaaatgtgg tataataaag ccaagtaaag agaaacgaga
    21601 agcacatgta tattgaaatg gtagatgaaa ctggtcaagt ttcaaaagaa atgttgcaac
    21661 aaacccaaga aattttggaa tttgcagccc aaaaattagg aaaagaagac aaggagatgg
    21721 cagtcacttt tgtgaccaat gagcgtagtc atgaacttaa tctggagtac cgtgacaccg
    21781 accgtccgac agatgtcatc agccttgagt ataaaccaga attggaaatt gcctttgacg
    21841 aagaggattt gcttgaaaat ccagaattgg cagagatgat gtctgagttt gatgcctata
    21901 ttggggaatt gttcatctct atcgataagg ctcatgagca ggccgaagaa tatggtcaca
    21961 gctttgagcg tgagatgggc ttcttggcag tacacggctt tttacatatt aacggctatg
    22021 atcactacac tccggaagaa gaagcggaga tgttcggttt acaagaagaa attttgacag
    22081 cctatggact cacaagacaa taaacgaaaa tggaaaaatc gtgacctgat atccagttta
    22141 gaatttgctt tgacaggtat ttttactgct atcaaggaag aacgaaatat gcgaaaacat
    22201 gcagtgacgg ctctagtggt tatccttgca ggttttgttt ttcaggtgtc acgaatcgaa
    22261 tggctctttc tcctattgag cattttcttg gtagtagcct ttgagattat caactctgct
    22321 attgaaaata tggtggattt ggccagtcac tatcactttt ccatgctggc taaaaatgcc
    22381 aaggatatgg cggctggtgc ggtattagtg gtttctcttt tcgcagcctt aacaggcgca
    22441 ttgatttttc tcccgcgaat ctgggattta ttattttaaa cagtaagagg aaattatgac
    22501 atttaaatca ggctttgtag ccattttagg acgtcctaac gttgggaagt caaccttttt
    22561 aaatcacgtc atggggcaaa agattgccat catgagtgac aaggcgcaga caacgcgcaa
    22621 caaaatcatg ggaatttaca cgactgataa ggagcaaatt gtctttatcg acacaccagg
    22681 gattcacaaa cctaaaacag ctctcggaga tttcatggtt gagtctgcct acagtaccct
    22741 tcgcgaagtg gacaccgttc ttttcatggt gcctgctgat gaagcgcgtg gtaaggggga
    22801 cgatatgatt atcgagcgtc tcaaggctgc caagattcct gtgattttgg tggtgaataa
    22861 aatcgataag gtccatccag accagctctt gtctcagatt gatgacttcc gtaatcaaat
    22921 ggactttaag gaaattgttc caatctcagc ccttcaggga aataacgtgt ctcgtctagt
    22981 ggatattttg agtgaaaatc tggatgaagg tttccaatat ttcccgtctg atcaaatcac
    23041 agaccatcca gaacgtttct tggtttcaga aatggttcgc gagaaagtct tgcacctaac
    23101 tcgtgaagag attccgcatt ctgtagcagt agttgttgac tctatgaaac gagacgaaga
    23161 gacagacaag gttcacatcc gtgcaaccat catggtcgag cgcgatagcc aaaaagggat
    23221 tatcatcggt aaaggtggcg ctatgcttaa gaaaatcggt agcatggccc gtcgtgatat
    23281 cgaactcatg ctaggagaca aggtcttcct agaaacctgg gtcaaggtca agaaaaactg
    23341 gcgcgataaa aagctagatt tggctgactt tggctataat gaaagagaat actaagtaga
    23401 ggtaggctca tgcctgcttc ttgtttttac agaaggagga cttatgcctg aattacctga
    23461 ggttgaaacc gtttgtcgtg gcttagaaaa attgattata gggaagaaga tttcgagtat
    23521 agaaattcgc taccccaaga tgattaagac ggatttggaa gagtttcaaa gggaattgcc
    23581 tagtcagatt atcgagtcaa tgggacgtcg tggaaaatat ttgctttttt atctgacaga
    23641 caaggtcttg atttcccatt tgcggatgga gggcaagtat ttttactatc cagaccaagg
    23701 acctgaacgc aagcatgccc atgttttctt tcattttgaa gatggtggca cgcttgttta
    23761 tgaggatgtt cgcaagtttg gaaccatgga actcttggtg cctgaccttt tagacgccta
    23821 ctttatttct aaaaaattag gtcctgaacc aagcgaacaa gactttgatt tacaggtctt
    23881 tcaatctgcc cttgccaagt ccaaaaagcc tatcaaatcc catctcctag accagacctt
    23941 ggtagctgga cttggcaata tctatgtgga tgaggttctc tggcgagctc aggttcatcc
    24001 agctagacct tcccagactt tgacagcaga agaagcgact gccattcatg accagaccat
    24061 tgctgttttg ggccaggctg ttgaaaaagg tggctccacc attcggactt ataccaatgc
    24121 ctttggggaa gatggaagca tgcaggactt tcatcaggtc tatgataaga ctggtcaaga
    24181 atgtgtacgc tgtggtacca tcattgagaa aattcaacta ggcggacgtg gaacccactt
    24241 ttgtccaaac tgtcaaagga gggactgatg ggaaaaatca tcggaatcac tgggggaatt
    24301 gcctctggta agtcaactgt gacaaatttt ctaagacagc aaggctttca agtagtggat
    24361 gccgacgcag tcgtccacca actacagaaa cctggtggtc gtctgtttga ggctctagta
    24421 cagcactttg ggcaagaaat cattcttgaa aacggagaac tcaatcgccc tctcctagct
    24481 agtctcatct tttcaaatcc tgaagagcaa aaatggtcta agcaaattca aggggagatt
    24541 atccgtgagg aactggctac tttgagagaa cagttggctc agacagaaga gattttcttc
    24601 atggatattc ccctactttt tgagcaggac tacagcgatt ggtttgctga gacttggttg
    24661 gtctatgtgg accgagatac ccaagtagaa cgcttaatga aaagggacca gttgtccaag
    24721 gatgaagctg agtctcgtct ggcagcccag tggcctttag aaaaaaagaa agatttggcc
    24781 agccaggttc ttgataataa tggcaatcag aaccagcttc ttaatcaagt gcatatcctt
    24841 cttgagggag gtaggcaaga tgacagagat taactggaag gataatctgc gcattgcctg
    24901 gtttggtaat tttctgacag gagccagtat ttctttggtt gtacctttta tgcccatctt
    24961 cgtggaaaat ctaggtgtag ggagtgagca agtcgctttt tatgcaggct tagcaatttc
    25021 tgtctctgct atttccgcgg cgctcttttc tcctatttgg ggtattcttg ctgacaaata
    25081 cggccgaaaa cccatgatga ttcgggcagg tcttgctatg actatcacta tgggaggctt
    25141 ggcctttgtc ccaaatatct attggttaat ctttcttcgt ttactaaacg gtgtatttgc
    25201 aggttttgtt cctaatgcaa cggcactgat agccagtcag gttccaaagg agaaatcagg
    25261 ctctgcctta ggtactttgt ctacaggcgt agttgcaggc actctaactg gtccctttat
    25321 tggtggcttt atcgcagaat tatttggcat tcgtacagtt ttcttactgg ttggtagttt
    25381 tctattttta gctgctattt tgactatttg ctttatcaag gaagattttc aaccagtagc
    25441 caaggaaaag gctattccaa caaaggaatt atttacctcg gttaaatatc cctatctttt
    25501 gctcaatctc tttttaacca gttttgtcat ccaattttca gctcaatcga ttggccctat
    25561 tttggctctt tatgtacgcg acttagggca gacagagaat cttctttttg tctctggttt
    25621 gattgtgtcc agtatgggct tttccagcat gatgagtgca ggagtcatgg gcaagctagg
    25681 tgacaaggtg ggcaatcatc gtctcttggt tgtcgcccag ttttattcag tcatcatcta
    25741 tctcctctgt gccaatgcct ctagccccct tcaactagga ctctatcgtt tcctctttgg
    25801 attgggaacc ggtgccttga ttcccggggt taatgcccta ctcagcaaaa tgactcccaa
    25861 agccggcatt tcgagggtct ttgccttcaa tcaggtattc ttttatctgg gaggtgttgt
    25921 tggtcccatg gcaggttctg cagtagcagg tcaatttggc taccatgctg tcttttatgc
    25981 gacgagcctt tgtgttgcct ttagttgtct ctttaacctg attcaatttc gaacattatt
    26041 aaaagtaaag gaaatctagt gcgagtaaaa attaatctca aatgctcctc ttgtggcagt
    26101 atcaattacc taaccagtaa aaattcaaaa acccatccag acaagattga ggttttaaag
    26161 tattgtccca aggaaagaaa agtaacccta catcttgaat ctaagtagat tttatggtaa
    26221 aataataggg attttaagga gtttgatatg tataacctat tattaaccat tttattagta
    26281 ttatctgttg tgattgtgat tgcaattttc atgcaaccaa ccaaaaacca atccagcaat
    26341 gtatttgatg ccagttcagg tgatttgttt gaacgcagta aagctcgcgg ttttgaagct
    26401 gtaatgcagc gtttgacagg gattttagtc tttttctggc tagccattgc cttagcattg
    26461 acggtattat caagtagata agaaaataat gggcaggact aggtctttgc ctctttttat
    26521 ttttaaagga tgtttgagaa ggttttacag taaaagaaaa ttaaaaaatc tagaaagaaa
    26581 atatgaaaga tagaataaaa gaatatttac aagacaaggg aaaggtgact gttaatgatt
    26641 tggctcaggc tttgggaaaa gacagttcca aggattttcg tgagttgatt aaaaccttgt
    26701 ccttaatgga aagaaagcac caaattcgtt ttgaagaaga tggtagtctg acattagaaa
    26761 ttaagaaaaa acatgagatt accctcaagg ggatttttca tgcccataaa aatggctttg
    26821 gctttgttag tctggaaggc gaggaggacg acctttttgt agggaaaaat gatgtcaact
    26881 atgctattgc tggtgatacc gtcgaggtag tgattaagaa agtcgctgac cgcaataagg
    26941 gaacagcagc agaagccaaa attattgata tcctagaaca cagtttgaca acagttgtcg
    27001 ggcaaatcgt tctggatcag gaaaaaccta agtatgctgg ctatattcgt tcaaaaaatc
    27061 agaaaatcag tcaaccgatt tatgttaaga aaccagccct aaaattagaa ggaacagaag
    27121 ttctcaaagt ctttatcgat aaatacccaa gcaagaaaca tgatttcttt gtcgcgagtg
    27181 ttctcgatgt ggtgggacac tcaacggatg tcggaattga tgttcttgag gttttggaat
    27241 caatggacat tgtatccgag tttccagaag ctgttgttaa ggaagcagaa agtgtgcctg
    27301 atgctccgtc tcaaaaggat atggaaggtc gtctggatct aagagatgaa attaccttta
    27361 ccattgacgg tgcggatgcc aaggacttgg acgatgcagt gcatatcaag gctctgaaaa
    27421 atggcaatct ggagcttggg gttcacatcg cagatgtttc ttattatgtg accgaggggt
    27481 ctgcccttga caaggaagcc cttaaccgtg cgacttctgt ttacgtgaca gaccgagtgg
    27541 tgccaatgct tccagaacga ctatcaaatg gcatctgctc tctcaatccc caagttgacc
    27601 gcctgaccca gtctgctatt atggagattg ataaacatgg tcgtgtggtc aactatacca
    27661 ttacacaaac agttatcaag accagttttc gtatgaccta tagcgatgtc aatgatatcc
    27721 tagctggcga tgaagaaaag agaaaagaat atcataaaat tgtaccaagt atcgaactca
    27781 tggccaagct tcatgaaact ttagaaaaca tgcgtgtgaa acgtggagct ctcaattttg
    27841 ataccaatga agcgaagatt ttagtggata aacaaggtaa gcctgttgat atcgttcttc
    27901 ggcagcgtgg tattgccgag cggatgattg agtcttttat gttgatggct aatgaaacag
    27961 ttgccgaaca tttcagcaag ttggatttgc cttttatcta tcgaattcac gaggagccta
    28021 aggctgaaaa ggttcagaag tttattgatt atgcttcgag ttttggcttg cgcatttatg
    28081 ggactgccag tgagattagc caggaggcac ttcaagacat catgcgtgct gttgagggag
    28141 aaccttatgc agatgtattg tccatgatgc ttcttcgctc tatgcagcag gctcgttatt
    28201 tggagcacaa tcacggccac tatggactag ctgctgacta ttatactcac tttaccagtc
    28261 caattcgtcg ttatccagac cttcttgttc accgtatgat tcgggattac ggccgttcta
    28321 aggaaatagc agagcatttt gaacaagtga ttccagagat tgcgacccag tcttccaacc
    28381 gtgaacgtcg tgccatagaa gctgagcgtg aagtcgaagc catgaaaaag gctgagtata
    28441 tggaagaata cgtgggtgaa gagtatgatg cagttgtatc aagtattgtc aaattcggtc
    28501 tctttgtcga attgccaaac acagttgaag gcttgattca catcactaat ctacctgaat
    28561 tttatcattt caatgagcgt gatttgactc ttcgtggaga aaaatcaggt atcactttcc
    28621 gagtgggtca gcagatccgt atccgtgttg aaagagcgga taaaatgact ggagagattg
    28681 atttttcatt cgtacctagt gagtttgatg tgattgaaaa aggcttgaaa cagtctagtc
    28741 gtagtggcag agggcgtgat tcaaatcgtc gttcggataa gaaggaagac aagagaaaat
    28801 caggacgctc aaatgataag cgtaagcatt cacaaaaaga caagaagaaa aaaggaaaga
    28861 aaccttttta caaggaagta gctaagaaag gagccaagca tggcaaaggg cgagggaaag
    28921 gtcgtcgcac aaaataaaaa ggcacgccac gactatacaa tcgtagatac gctagaggca
    28981 gggatggtcc tgactggaac tgaaatcaag agtgtacgag ctgctcgaat taatctcaag
    29041 gatggctttg ctcaagtgaa aaatggagaa gtttggctga gcaatgttca tatcgcgcct
    29101 tacgaagagg gcaatatctg gaaccaggaa ccagaacgtc gtcgtaaact cctgctccat
    29161 aaaaggcaaa ttcaaaaatt ggaacaagag accaaaggga caggaatgac cttagttccc
    29221 cttaaggtct atataaaaga tggctacgct aagcttcttt taggacttgc caaagggaag
    29281 catgactatg acaaacggga gtctatcaaa cgtcgtgagc aaaatcgaga tatcgcgcgt
    29341 gtgatgaaag ctgttaatca gcgataaaaa gaggaattga aaatggaaaa attagttgcc
    29401 tataaacgca tgcctttgtg gaataaacaa acaatgcctg aagctgttca gcaaaagcac
    29461 aatacaaaag ttgggacttg ggggaaaatt actgtcttga agggagctct caagtttatt
    29521 gaattgacag aagaagggga agttctagct gaacacctct ttgaagcagg ggcagacaat
    29581 ccaatggccc aacctcaagc ctggcaccga gtggaagctg ccacagatga tgtggaatgg
    29641 tacttggaat tttattgtaa acctgaggat tattttgcta aaaaatacaa taccaatcct
    29701 gttcattcag aggtcctaga ggccatggag acagtgaaac aagggaaagc tttggatttg
    29761 ggttgtggtc aggggcgtaa ttctcttttt ctagcccagc aagattttga tgtgacggct
    29821 gtagatcaaa atggactagc tcttgaaatc ttgcaaagca ttgtggagca ggaagatttg
    29881 gacatgcctg ttggccttta cgatatcaat tcagctagca ttgaacaaga atatgatttt
    29941 atcgtttcaa cagttgttct catgtttcta caagcggacc gcattccagc tattattcaa
    30001 aatatgcagg agaaaaccag tgttggtggt tacaacctta tcgtttgtgc catggacacg
    30061 gaggattatc cttgctcggt taacttccca ttcaccttta aagaaggaga actggcagac
    30121 tattacaagg attgggaatt ggttaagtac aatgaaaatc caggccattt gcatcgtcgc
    30181 gatgagaatg gcaatcgtat tcaactacgc tttgcgacct tactagctaa gaaaatcaag
    30241 taaacacaca tgaagattag gaattttcct gatctttttt cttttttacg aatgatatag
    30301 aaaaggaggg aattcatgtt tgttgcgaga gatgctaggg gagaattggt aaatgtgtta
    30361 gaggataaac ttgagaagca agcatacacc tgcccagctt gtggaggcca gctccatttg
    30421 cgtcaaggac caagtgtacg gacgcatttt gcccataaat ccttaaaaga ctgtgatttt
    30481 ttctttgaaa atgaaagtcc agaacacctg gccaataagg aatccctcta tcactggttg
    30541 aaaaaagaga caaaggttca attagagtac ccgctttcag aacttaaaca gattgcggat
    30601 gtatttgtaa atggcaatct agctctagaa gttcagtgta gtcccttgcc tcagaaagtc
    30661 cttaaagagc gaagtgaggg ctatcgtagt cagggttacc aagtactgtg gttgctgggt
    30721 caaaaactgt ggctcaagga gcgtttgact cgtctacagc aaggttttct ttatttcagt
    30781 caaaacatgg gcttttatgt ttgggaatta gacaaggaaa aacaagtttt aagactcaaa
    30841 tacctgattt accaggatct ccgcggtaaa ctccattatc aaatcaagga attttcctat
    30901 ggtcaaggta gtttattgga aatattgcgt cttccctata agagacaaaa aatatctcat
    30961 tttacagttt ctgaggacaa ggacatctgt cgctatatcc agcaacaact ttattatcaa
    31021 aatctctttt ggatgaaaga acaagcagaa gcctatcaaa agggagaaaa tatcctgact
    31081 tatggactga aagaatggta tccacaaatt cgaccaatag tgggcaaatt tttccagatt
    31141 gaacaagact tgactagcta ttatcagcac ttttatacct attaccaaaa aaatcctcaa
    31201 aatgattggc aaaagcttta tccaccagcc ttttatcagc aatatttctt gaaaaatatg
    31261 gtagaataga aaggatggag gaatctaatg gtattacaaa gaaatgaaat aaatgaaaaa
    31321 gatacatggg atctatcaac gatctaccca actgaccagg cttgggaaga agccttaaaa
    31381 gatttaacag aacaattgga gacagtagcc cagtatgaag gccatctctt ggatagtgcg
    31441 gataacctac tagaaatcac tgaattttct cttgaaatgg aacgccagat ggagaagctt
    31501 tacgtttatg ctcatatgaa gaatgaccag gatacacgtg aagctaagta tcaagagtac
    31561 tatgccaagg ccatgacact ctacagccag ttagaccaag ccttttcatt ctatgatcct
    31621 gaatttatgg agattagcga aaagcagtat gctgactttt tagaagctca accaaagctg
    31681 caggtttatc aacactattt tgacaagctc ttgcaaggca aggatcacgt tctttcacaa
    31741 cgtgaagaag aattattggc tggagctgga gaaatctttg gttcagcaag tgaaaccttc
    31801 gctatcttgg acaatgcgga tattgtgttc ccttatgtcc tagacgatga tggtaaagaa
    31861 gttcagctat ctcatgggac ttacacacgt ttgatggagt ctaaaaaacg tgaggttcgc
    31921 cgtggtgcct atcaagctct ttatgcgact tacgaacaat tccaacacac ctatgccaaa
    31981 accttgcaaa ccaatgttaa ggtgcaaaat taccgtgcta aagttcgtaa ctacaagagt
    32041 gctcgtcatg cagccctcgc agcgaatttt gttccagaaa gtgtttatga caatttggta
    32101 gcagcagttc gcaagcattt gccactctta catcgctatc ttgagcttcg ttcaaaaatc
    32161 ttggggattt cagatctcaa gatgtacgat gtctacacac cgctttcatc tgttgaatac
    32221 aattttacct accaagaagc cttgaaaaaa gcagaagatg ctttggcagt cttgggtgag
    32281 gattacttga gccgtgtcaa acgtgccttc agcgagcgtt ggattgatgt ttacgaaaat
    32341 caaggcaagc gttcaggtgc ctactctggt ggttcttacg ataccaatgc ctttatgctt
    32401 ctcaactggc aggacaatct ggacaatctc tttactcttg ttcatgaaac aggtcacagt
    32461 atgcattcaa gctatactcg tgaaactcag ccttatgttt acggagatta ctctatcttt
    32521 ttggctgaga ttgcctcaac taccaatgaa aatatcttga cggagaaatt attggaagaa
    32581 gtggaagacg acgcaacacg ctttgctatt ctcaataact tcctagatgg tttccgtgga
    32641 acagttttcc gccaaactca atttgctgag tttgaacacg ccattcacca agcagatcaa
    32701 aatggggagg tcttgacaag cgatttccta aataaactct acgcagactt gaaccaagag
    32761 tattatggtt tgagtaagga agacaatcct gaaatccaat acgagtgggc tcgcattcca
    32821 cacttctact ataactacta tgtatatcaa tattcaactg gctttgcggc cgcctcagcc
    32881 ttggctgaaa aaattgtcca tggtagtcaa gaagaccgtg accgctatat cgactacctc
    32941 aaggcaggta agtcggacta tccacttaat gtcatgagaa aagctggtgt tgatatggag
    33001 aaggaagact acctcaacga tgcctttgca gtctttgaac gccgtttaaa tgagtttgaa
    33061 gcccttgttg aaaaattagg attggcataa aatggttgaa tcgtatagta agaatgctaa
    33121 ccataacatg cgtcgtcctg tcgtcaaaga agaaattgta gacttgatgc gtcagcgtca
    33181 aaagcaggtc acaggtttct tgaaagaatt ggaagaattt gcccgcaagg aaaatattcc
    33241 tattattccc catgaaacgg ttgcttattt ccgttttctt atggaaacca tgcagcctaa
    33301 aaatattctg gaaattggga cggctatcgg tttttcagct ctcttgatgg ctgaacatgc
    33361 gccaaatgct aagattacaa ctattgatcg taatccagaa atgattggtt ttgccaagga
    33421 aaattttgcc cagtttgaca gtcgcaagca aatcactctc ctagagggag atgcggtgga
    33481 tgtcttatct acactgacag agtcttatga tttcgtcttt atggattctg ccaagtctaa
    33541 atacatcgtc tttctgccag aaatcctcaa acatttggaa gttggtggtg tggttgtctt
    33601 ggatgatatt tttcaaggtg gtgatgttgc caaggatatt atggaagtcc gtcgtggtca
    33661 gcgaaccatt tatcgaggcc ttcaaaaatt atttgatgca accttagaca atccagaact
    33721 caccgcaaca ttagtgcctt taggagatgg tattctcatg cttcgtaaaa atgtagcaga
    33781 tgttcaactg tctgaaagcg aatgattttc agaaaaattt aagaaaaaat agtaaaatag
    33841 atagagtaac acttatctca aaggagtaga catgaagaaa aaattattgg caggtgccat
    33901 cacactatta tcagtagcaa ctttagcagc ttgttcgaaa gggtcagaag gagcagacct
    33961 tatcagcatg aaaggggatg tcatcacaga acatcaattt tatgagcaag tgaaaaacaa
    34021 cccttcagcc caacaagtct tgttaaatat gaccatccaa aaagtttttg aaaaacaata
    34081 tggctcagag cttgatgata aagaggttga tgatactatt gccgaagaaa aaaaacaata
    34141 tggcgaaaac taccaacgtg tcttgtcaca agcaggtatg actcttgaaa cacgtaaagc
    34201 tcaaattcgt acaagtaaat tagttgagtt ggcagttaag aaggtagcag aagctgaatt
    34261 gacagatgaa gcctataaga aagcctttga tgagtacact ccagatgtaa cggctcaaat
    34321 catccgtctt aataatgaag ataaggccaa agaagttctc gaaaaagcca aggcagaagg
    34381 tgctgatttt gctcaattag ccaaagataa ttcaactgat gaaaaaacaa aagaaaatgg
    34441 tggagaaatt acctttgatt ctgcttcaac agaagtacct gagcaagtca aaaaagccgc
    34501 tttcgcttta gatgtggatg gtgtttctga tgtgattaca gcaactggca cacaagccta
    34561 cagtagccaa tattacattg taaaactcac taagaaaaca gaaaaatcat ctaatattga
    34621 tgactacaaa gaaaaattaa aaactgttat cttgactcaa aaacaaaatg attcaacatt
    34681 tgttcaaagc attatcggaa aagaattgca agcagccaat atcaaggtta aggaccaagc
    34741 cttccaaaat atctttaccc aatatatcgg tggtggagat tcaagctcaa gcagtagtac
    34801 atcaaacgaa tagtccaaat caatgagtca gggaaaaaaa ctcgacttca ggaaaaaatg
    34861 aagcaaacat tcccaaaata aaacgcatag tacaaggttt gtactgcccc caaaagttag
    34921 acaattaatt tatctgaagg atttagttct gtattgcaca gggctaagtc cttttagttt
    34981 taccttaatt ctcttattgt tgtaataatc aata
//
LOCUS       DBEJKC010000017        34620 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.017, whole genome shotgun sequence.
ACCESSION   DBEJKC010000017 DBEJKC010000000
VERSION     DBEJKC010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34620
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.017"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            572..1024
                     /locus_tag="ACL3G6_000839"
                     /pseudo
     CDS             572..1024
                     /locus_tag="ACL3G6_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
     gene            1043..2380
                     /locus_tag="ACL3G6_000840"
     CDS             1043..2380
                     /locus_tag="ACL3G6_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0545399.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2459..3343
                     /locus_tag="ACL3G6_000841"
     CDS             2459..3343
                     /locus_tag="ACL3G6_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0545400.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3343..4176
                     /locus_tag="ACL3G6_000842"
     CDS             3343..4176
                     /locus_tag="ACL3G6_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0545401.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLITIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4195..6288
                     /gene="nanB"
                     /locus_tag="ACL3G6_000843"
     CDS             4195..6288
                     /gene="nanB"
                     /locus_tag="ACL3G6_000843"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HGR0545402.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6301..7404
                     /locus_tag="ACL3G6_000844"
     CDS             6301..7404
                     /locus_tag="ACL3G6_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGR0545403.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7578..8276
                     /locus_tag="ACL3G6_000845"
     CDS             7578..8276
                     /locus_tag="ACL3G6_000845"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGR0545404.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8295..9812
                     /locus_tag="ACL3G6_000846"
     CDS             8295..9812
                     /locus_tag="ACL3G6_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGR0545405.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9937..11265
                     /locus_tag="ACL3G6_000847"
     CDS             9937..11265
                     /locus_tag="ACL3G6_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0545406.1"
                     /translation="MKFRKLACTVLAGAVVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11517..12383
                     /locus_tag="ACL3G6_000848"
     CDS             11517..12383
                     /locus_tag="ACL3G6_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0545407.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12399..13238
                     /locus_tag="ACL3G6_000849"
     CDS             12399..13238
                     /locus_tag="ACL3G6_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0545408.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13511..13963
                     /locus_tag="ACL3G6_000850"
     CDS             13511..13963
                     /locus_tag="ACL3G6_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGR0545409.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCYEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14060..14404
                     /locus_tag="ACL3G6_000851"
     CDS             14060..14404
                     /locus_tag="ACL3G6_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545410.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMAWIIRGIVNALIGRYIKLGAY
                     AAKYGISMARSILSRAAATAAARVGLSTKISGWILRVAVNVADVYGNFAYNIAAAWDA
                     HDKIPNNGRINF"
     gene            14414..14605
                     /locus_tag="ACL3G6_000852"
     CDS             14414..14605
                     /locus_tag="ACL3G6_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545411.1"
                     /translation="MKALCIFLLNMLAWTVLAMIIRGGLDGFNEHTWSTILIASLFGV
                     YDYKPIDKNRKKSKRKKKK"
     gene            14688..15332
                     /locus_tag="ACL3G6_000853"
     CDS             14688..15332
                     /locus_tag="ACL3G6_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGR0545412.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15501..16418
                     /locus_tag="ACL3G6_000854"
     CDS             15501..16418
                     /locus_tag="ACL3G6_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HGR0545413.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16436..17320
                     /locus_tag="ACL3G6_000855"
     CDS             16436..17320
                     /locus_tag="ACL3G6_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGR0545414.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGLVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASMTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17336..18187)
                     /locus_tag="ACL3G6_000856"
     CDS             complement(17336..18187)
                     /locus_tag="ACL3G6_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGR0545415.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKNSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18387..20444
                     /gene="pbp2b"
                     /locus_tag="ACL3G6_000857"
     CDS             18387..20444
                     /gene="pbp2b"
                     /locus_tag="ACL3G6_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HGR0545416.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANDGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSELTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20455..21051
                     /gene="recR"
                     /locus_tag="ACL3G6_000858"
     CDS             20455..21051
                     /gene="recR"
                     /locus_tag="ACL3G6_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HGR0545417.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21227..22270
                     /locus_tag="ACL3G6_000859"
     CDS             21227..22270
                     /locus_tag="ACL3G6_000859"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HGR0545418.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVDYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALELAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22354..23727
                     /gene="murF"
                     /locus_tag="ACL3G6_000860"
     CDS             22354..23727
                     /gene="murF"
                     /locus_tag="ACL3G6_000860"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HGR0545419.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLSANDQILLKGSNSMNLAMLVE
                     SLENETK"
     gene            23714..24325
                     /locus_tag="ACL3G6_000861"
     CDS             23714..24325
                     /locus_tag="ACL3G6_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase N-terminal domain-containing
                     protein"
                     /protein_id="HGR0545420.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGQREQYLD"
     gene            24416..25120
                     /locus_tag="ACL3G6_000862"
     CDS             24416..25120
                     /locus_tag="ACL3G6_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HGR0545421.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25339..26712
                     /gene="ftsA"
                     /locus_tag="ACL3G6_000863"
     CDS             25339..26712
                     /gene="ftsA"
                     /locus_tag="ACL3G6_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HGR0545422.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRTGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26729..27988
                     /gene="ftsZ"
                     /locus_tag="ACL3G6_000864"
     CDS             26729..27988
                     /gene="ftsZ"
                     /locus_tag="ACL3G6_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HGR0545423.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETAELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27993..28664
                     /locus_tag="ACL3G6_000865"
     CDS             27993..28664
                     /locus_tag="ACL3G6_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HGR0545424.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28674..29213
                     /locus_tag="ACL3G6_000866"
     CDS             28674..29213
                     /locus_tag="ACL3G6_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HGR0545425.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29213..29476
                     /locus_tag="ACL3G6_000867"
     CDS             29213..29476
                     /locus_tag="ACL3G6_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HGR0545426.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29533..30258
                     /locus_tag="ACL3G6_000868"
     CDS             29533..30258
                     /locus_tag="ACL3G6_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HGR0545427.1"
                     /translation="MEWIKKVEDSYAPFLTPFINPHQEKLLKILAKTYGLACSSSGEF
                     VSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHLTHAKILGTVINQLGIERKLF
                     GDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEERPFTEKIDKLEQYRELDLSV
                     SSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDKSDYTVQVGDLISVRKFGRLR
                     LLQDKGQTKKEKKKITVQLLLSK"
     gene            30267..31055
                     /gene="divIVA"
                     /locus_tag="ACL3G6_000869"
     CDS             30267..31055
                     /gene="divIVA"
                     /locus_tag="ACL3G6_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HGR0545428.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPVPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVEAPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31403..34195
                     /gene="ileS"
                     /locus_tag="ACL3G6_000870"
     CDS             31403..34195
                     /gene="ileS"
                     /locus_tag="ACL3G6_000870"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HGR0545429.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKIIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEAQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFADAVAEGFEEK"
BASE COUNT        10672 a         6105 c         7528 g        10315 t
ORIGIN      
        1 attgaaaacg gtaacaaaac taatttagag aatgaaatat agagtatttc tctcttaaaa
       61 gtttttggtg aaacgagatg tagaaaggag atttagccaa agagtctatt agtgctagaa
      121 taatagatta gaattatttt agaaaaacga agtgagcagc ttataaattc aagtccccaa
      181 atagattcat actagtatct tttgcaaaaa ataaagggcg acttccttca tgaatatcaa
      241 tttcatctat aaggaaggta gctaattgaa ctaacttatt tattctgttt gtcgctagaa
      301 aaatcagacc tccttgtgaa gattgaggag atacttaatg aaaatcaaag aagaaactag
      361 caagctagta gcagattgcc caaaacaccg ctttgaggtt gtagataaga ctgacgtata
      421 taatccaagg tgaagcgact gtggtttgaa gagattttca aagagtatag gctagagagt
      481 agtgttttta tgtccttcta gtagaaaatg ctagacagaa gaatggggaa cttggatagg
      541 aaaaatagat tgagaaagga ggttagaaga gatgattatt acaaaaatta gccgtttagg
      601 aacttatgtg ggagtaaatc cacattttgc aacattaata gattttctag aaaaaacagg
      661 actagaaaat ttaacagaag gttcgattgt tatcgatggt aatcgattgt ttgggaattg
      721 atttacttat ctagcagatg gtcaagcagg ggctttcttt gaaacacacc aaaaatattt
      781 ggatattcat ttagttttgg aaaacgaaga agccatggct gttacatcgc cggaaaatgt
      841 aagcgttacc caagaatatg atgaagagaa agatattgaa ttatacacag ggaaagtgga
      901 acagttggtt catttgagag ctggcgaatg cctcatcact tttccagaag atttacatca
      961 acccaaggtt cgtataaatg atgaacctgt gaaaaaagtt gtctttaaag ttgcgatttc
     1021 ttaatgtaga aagagaagaa cgatgaaaaa aatgagaaag tttttatgtc tagctggaat
     1081 tgcgctagcg gctgttgcct tggtagcttg ttcaggaaaa aaagaagcta caactagtac
     1141 tgaaccacca acagaattat ctggtgagat tacaatgtgg cactccttta ctcaaggacc
     1201 ccgtttagaa agtattcaaa aatcagcaga tgctttcatg caaaagcatc caaaaacgaa
     1261 aatcaagatt gaaacatttt cttggaatga cttctatact aaatggacta caggtttagc
     1321 aaatggaaat gtgccagata tcagtacagc tcttcctaac caagtaatgg aaatggtcaa
     1381 ctcagatgct ttggttccgc taaatgattc tatcaagcgt attggacaag ataaatttaa
     1441 cgaaactgcc ttaaatgaag caaaaatcgg agatgattac tactctgttc ctctttattc
     1501 acatgcacaa gtcatgtggg ttagaacaga tttgttaaaa gaacataata ttgaggttcc
     1561 taaaacttgg gatcaactct atgaagcttc taaaaaattg aaagaagctg gagtttatgg
     1621 cttgtctgtt ccgtttggaa caaatgactt aatggcaaca cgtttcttga acttctacgt
     1681 acgtagtggt ggaggaagcc tcttaacaaa agatcttaaa gcagacttga caagccaact
     1741 tgctcaagat ggtattaaat actgggttaa attgtataaa gaaatctcac ctcaagattc
     1801 tttgaacttt aatgtccttc aacaagctac cttgttctat caaggaaaaa cagcatttga
     1861 ctttaactct ggcttccata tcggaggaat taatgccaac agtcctcaat tgattgattc
     1921 gattgatgct tatcctattc caaaaatcaa agagtctgat aaagaccaag gaattgaaac
     1981 ctcaaacatt ccaatggttg tttggaaaaa ttcaaaacat ccagaagttg ctaaagcatt
     2041 cttagaagca ctttataatg aagaagacta cgttaaattc cttgattcaa ctccagtagg
     2101 tatgttgcca actattaagg ggattagcga ttctgcagcc tataaagaaa atgaaactcg
     2161 taagaagttt aaacatgctg aagaagtaat tactgaagct gttaaaaaag gtactgctat
     2221 tggttatgaa aatggaccaa gtgtacaagc tggtatgttg actaaccaac acattattga
     2281 acaaatgttc caagatatca ttacaaatgg aacagatcct atgaaagcag caaaagaagc
     2341 agaaaaacaa ttaaacgatt tatttgaggc tgttcagtag atgtaaaaga ctagaaaata
     2401 ggtgggctag tgagctgaaa agctctagcc caatcttgta aaagaaggga gaaggagaat
     2461 ggttaaagaa cgtaatttaa ctcgctggat atttgttttg ccagctatga ttatcgtagg
     2521 attactcttt gtttatccgt ttttctcgag tattttttat agctttacca ataagcattt
     2581 gattatgcct aattataaat ttgttggttt ggctaactat aaagctgtgc tatcagatcc
     2641 caacttcttt aatgcgttct ttaattcaat taagtggacc gttttctcat tagttggtca
     2701 agttttagta gggtttgtat tggctttagc tcttcacaga gtacgccact tcaagaaatt
     2761 atataggacc ttattgattg ttccttgggc atttcctacc atcgttattg ccttttcttg
     2821 gcagtggatt ctaaacgggg tttatggcta cttacctaat ctaatcgtaa aattaggttt
     2881 aatggaacat acacctgcat ttttgacaga tagtacatgg gcattcctat gtttggtgtt
     2941 tatcaacatt tggtttggag caccaatgat tatggttaat gtgctttcag ctttgcaaac
     3001 agtaccagaa gaacaatttg aggctgctaa gatagatggt gcttcaagtt ggcaggtgtt
     3061 caagtttatc gtctttccac atattaaagt ggttgtagga cttctagttg ttttgagaac
     3121 tgtatggatc tttaataact ttgacattat ctacctcatt actggtggtg gaccagccaa
     3181 tgctacaacg acgcttccaa tttttgctta caacctgggt tggggaacta aattgttggg
     3241 tcgtgcttca gcagttacag tattgctctt tatcttcttg gtggcgattt gctttatcta
     3301 ctttgctatc atcagtaagt gggaaaagga gggtagaaaa taatgaagaa gaaatccagt
     3361 atttatttag atattctctc acatgtactt ttagttggtg cgaccatcgt tgcaattttc
     3421 ccattggtat ggattatcat atcttctgtc aaagggaaag gggaattaac tcagtatcca
     3481 acacgatttt ggcctgaaca gtttacatta gattatttca ctcatgttat caacgatttg
     3541 cacttcattg ataacattcg aaacagttta atcattgcct tggctacaac cctcattacg
     3601 attattattt ctgctatggc agcctatggt attgttcgat tctttcctaa attgggagca
     3661 atcatgtcga gactactcgt cattacctat attttcccac caattttgtt agcaattccc
     3721 tattcaattg ccattgctaa agttgggtta acaaatagtt tatttggctt gatgatggtt
     3781 tatctatctt ttagtgttcc atatgcagtt tggctcttag ttggattttt ccaaacagtt
     3841 ccaattggaa ttgaagaagc ggctagaatt gatggtgcaa ataaatttgt tacgttttat
     3901 aaagttgtgc taccgattgt agcaccaggt attgtagcaa cagctattta tacatttatc
     3961 aatgcttgga atgaattcct gtatgccttg attttgatta acaatacagg aaagatgaca
     4021 gtagcagtag cccttcgttc acttaatggt tcagaaatac tagactgggg agatatgatg
     4081 gcagcgtctg ttattgtagt tcttccatca attattttct tctctatcat ccaaaataag
     4141 attgcaagtg gattatcaga aggatctgtg aagtagacga aagaaggaaa aaaaatgaat
     4201 aaaagaggtc tttattcaaa actaggaatt tctgttgtag gcattagtct tttaatggga
     4261 gttcctactt tgattcatgc gaatgaatta aactatggtc aactgtccat atctcctatt
     4321 tttcaaggag gttcatatca actgaacaat aagagtatag atatcagctc tttgttatta
     4381 gataaattgt ctggagagag tcagacagta gtaatgaaat ttaaagcaga tgaaccaaac
     4441 tctcttcaag ctttgtttgg cctatctaat agtaaagcag gctttaaaaa taattacttt
     4501 tcaattttca tgagagattc tggtgagata ggtgtagaaa taagagacgc ccaaaaggga
     4561 ataaattatt tattttctag accagcttca ttatggggaa agcataaagg acaggcagtt
     4621 gaaaatacac tagtatttgt atctgattct aaagataaaa catacacaat gtatgttaat
     4681 ggaatagaag tgttctctga aacagttgat acatttttgc caatttcaaa tataaatggt
     4741 atagataagg caacactagg agctgttaat cgtgaaggta aggaacatta cctcgcaaaa
     4801 ggaagtattg atgaaatcag tctatttaac aaagcaatta gtgatcagga agtttcaaat
     4861 attcccttgt caaatccatt tcagttaatt ttccaatcag gagattctac tcaagctaac
     4921 tattttagaa taccgacact atatacatta agtagtggaa gagttctatc aagtattgat
     4981 gcacgttatg gtgggactca tgattctaaa agtaagatta atattgccac ttcttatagt
     5041 gatgataatg ggaaaacgtg gagtgagcca atttttgcta tgaagtttaa tgactatgag
     5101 gagcagttag tttactggcc acgagataat aaattaaaga atagtcaaat tagtggaagt
     5161 gcttcattca tagattcatc cattgttgaa gataaaaaat ctgggaaaac gatattacta
     5221 gctgatgtta tgcctgcggg tattggaaat aataatgcaa ataaagccga ctcaggtttt
     5281 aaagaaataa atggtcatta ttatttaaaa ctaaagaaga atggagataa cgatttccgt
     5341 tatacagtta gagaaaatgg tgtcgtttat gatgaaacaa ctaataaacc tacaaattat
     5401 actataaatg ataagtatga agttttggag ggaggaaagt ctttaacagt cgaacaatat
     5461 tcggttgatt ttgatagtgg ctctttaaga gaaaaacata atggaaaaca ggtccctatg
     5521 aatgttttct acaaagattc gttatttaaa gtgactccta ctaattatat agcaatgaca
     5581 actagtcaga atagaggaga gagttgggaa caatttaagt tgttgcctcc gttcttagga
     5641 gaaaaacata atggaactta cttatgtccc ggacaaggtt tagcattaaa atcaagtaac
     5701 agattgattt ttgcaacata tactagtgga gaactaacct atctcatttc tgatgatagt
     5761 ggtcaaacat ggaagaaatc ctcagcttca attccgttta aaaatgcaac agcagaagca
     5821 caaatggttg aactgagaga tggtgtgatt agaacattct ttagaaccac tacaggtaag
     5881 atagcttata tgactagtag agattctgga gaaacatggt cgaaagtttc gtatattgat
     5941 ggaatccaac aaacttcata tggcacacaa gtatctgcaa ttaaatactc tcaattaatt
     6001 gatggaaaag aagcagtcat tttgagtaca ccaaattcta gaagtggccg taagggaggt
     6061 caattagttg ttggtttagt caataaagaa gatgatagta ttgattggaa ataccactat
     6121 gatattgatt tgccttcgta tggttatgcc tattctgcga ttacagaatt gccaaatcat
     6181 cacataggtg tgctgtttga aaaatatgat tcgtggtcga gaaatgaatt gcatttaagc
     6241 aatgtagttc agtatataga tttggaaatt aatgatttaa caaaataaag gagaaaaaac
     6301 atggttaaat acggtgttgt tggagcaggg tattttggag ctgaattggc tcgctacatg
     6361 caaaagaatg atggagcaga gattactctt ctctatgatc cagataatgc agaggcgatt
     6421 gcagaagaat tgggagcaaa agtagcaagt tccttagatg agttggtttc tagcgatgaa
     6481 gtagattgtg ttatcgtcgc aactccaaat aatcttcata aggaaccggt tattaaggct
     6541 gcacagcatg gtaaaaatgt tttctgtgaa aaaccaattg cgctttctta tcaagattgt
     6601 cgcgagatgg tagatgcgtg taaagaaaac aatgtaacct ttatggcagg acatattatg
     6661 aatttcttta atggtgttca tcatgcaaaa gaactcatta atcaaggagt tatcggagac
     6721 gttctatatt gtcatacagc tcgtaatggt tgggaagaac aacaaccgtc agtatcatgg
     6781 aaaaaaattc gtgaaaaatc aggtggtcac ttgtatcacc acatccatga attggattgc
     6841 gttcaattcc ttatgggggg catgcctgaa actgtaacca tgacaggtgg aaatgtggcc
     6901 catgaaggtg aacatttcgg tgatgaagat gatatgattt ttgtcaatat ggaattttct
     6961 aataagcgtt ttgccttgtt agaatggggt tcagcttatc gttggggtga acattatgtc
     7021 ttaatccaag gaagcaaagg tgccatccgc ttagacttat tcaactgtaa aggaactctt
     7081 aagctagatg ggcaagaaag ctatttcttg attcacgaat cgcaagaaga agatgatgat
     7141 cggactcgta tctatcatag tacagagatg gatggagcaa ttgcttatgg taaaccaggt
     7201 aaacgtactc cattatggct atcatctgtc attgataaag aaatgcgcta tctgcatgag
     7261 attatggaag gagccccagt atcagaagaa tttgcaaaac ttttgacagg tgaagctgcc
     7321 ctagaagcaa ttgctactgc agatgcttgt acccagtcta tgtttgaaga tcgcaaagta
     7381 aaattgtcag aaattgtaaa ataaattttg gtattctcct atttataggt cgacttgctc
     7441 ctctgaaagt acttttagag gagctgtttg actttgctag tttttgaaac tgaaatctat
     7501 tatactacaa actattgaaa gcgttttaat tttaaggtat aataatctca tagaaataaa
     7561 gaaaaggagg aaagaggatg ccacagatta gcaaagaagc cttgattgag caaatcaaag
     7621 atggaatcat cgtttcttgt caggctcttc ctcatgaacc gctttataca gaagcgggag
     7681 gggtgattcc cttgctggtc aaagcggctg agcaaggtgg agcagtcggt atccgagcaa
     7741 acagtgttcg cgatatcaag gaaattaagg aagtcactaa acttccaatc attgggatta
     7801 tcaaacgtga ttatccacct caggaaccct tcatcacggc tactatgaaa gaagttgatg
     7861 aattggcaga actggacatc gaggtgattg ctctggattg taccaagcgt gaacgctacg
     7921 atggtttgga aattcaagag ttcattcgtc aggttaagga gaaatatcct aatcagcttt
     7981 tgatggctga tactagtatc ttcgaagaag ggctagcagc tgtagaagca ggaattgact
     8041 ttgtcggaac aaccttatca ggctacacat cctacagtcc aaaagtagac ggtccagatt
     8101 ttgaattgat taagaaactc tgtgatgccg gtgtagatgt cattgcagaa ggaaaaattc
     8161 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggcatc gttgttggtg
     8221 gcgccattac tagaccaaaa gagattacag aacgcttcgt tgctagtctt aaataagatg
     8281 tgagagggag ttttatgttt aaagttttac aaaaagttgg aaaagctttt atgttaccta
     8341 tagctatact tcctgcagca ggtctacttt tggggattgg tggtgcactt tcaaacccaa
     8401 ccacgatagc aacttatcca atactagaca atagtatttt tcaatcaata ttccaagtaa
     8461 tgagctctgc aggagaggtt gtattcagta atttgtcact acttctctgt gtgggattat
     8521 gtattggctt agcgaaacga gataaaggaa ccgctgcgtt agcaggagta actggttact
     8581 tagttatgac tgcaacgatc aaagctttgg taaaactttt tatggcagaa ggatctgcaa
     8641 ttgatactgg agttattgga gcattagttg tcggaatagt tgccgtatat ttgcacaacc
     8701 gatataacaa tattcaatta ccttccgctt taggattctt tggaggttca cgcttcgttc
     8761 ctattgttac atcgttctct tctatcttga ttggctttgt cttctttgtt atttggccac
     8821 ctttccaaca acttcttgtt tctacaggtg gatatatttc tcaggcgggt ccaattggaa
     8881 cttttctata tggattttta atgagacttt ctggagcagt aggcttacat catataattt
     8941 accctatgtt ttggtatact gaacttggtg gtgttgaaac tgttgcagga caaacagtgg
     9001 ttggagctca aaaaatattt tttgctcaat tagccgatcc ggcccattct ggattattta
     9061 cagaaggaac aaggtttttt gcaggtcgtt tctcaacaat gatgttcggt ttaccggctg
     9121 cctgtttagc gatgtaccat agtgttccta aaaatcgtcg taaaaaatac gcgggtttgt
     9181 tttttggagt tgctttaaca tcttttatta ccggtattac agaaccaatt gaatttatgt
     9241 ttctattcgt cagtccggtt ctatatgttg ttcacgcatt ccttgatggt gttagcttct
     9301 ttattgcaga cgtcttaaat atttcaatag gaaacacatt ttcaggaggt gtaatcgatt
     9361 tcactttatt tggaattttg caggggaacg ctaagacgaa ttgggttctt cagattccaa
     9421 ttggacttat ttggagtgtt ttgtattata ttatttttag atggttcatt actcaattca
     9481 acgttctaac gccaggacga ggagaagaag tagattctaa agaaatttct gaatccgcag
     9541 attcaacttc aaatactgca gattatttaa aacaggatag cctacaaatt atcagagcct
     9601 tgggtggatc aaataatata gaagatgtag atgcttgtgt gacacgttta cgtgtagctg
     9661 taaaagaagt taatcaagtt gataaagcac ttttaaaaca aattggtgca gttgatgtct
     9721 tagaagtgaa gggtggcatt caagcaatct atggagcaaa agcaatctta tataaaaata
     9781 gtattaatga aattttaggt gtagatgatt aagtacttac tgacttaata aaaaacagag
     9841 gagagtgatg gatgagtagg atgaaatgaa atcgtataca agaaataaag aactcattat
     9901 ccaagttgga tacgcttatt acataggaga atacaaatga aatttagaaa attagcttgt
     9961 acagtacttg cgggtgctgt ggttcttggt cttgctgctt gtggcaattc tggcggaagt
    10021 aaagatgctg ccaaatcagg tggtgacggt gccaaaacag aaatcacttg gtgggcattc
    10081 ccagtattta cccaagaaaa aactggtgac ggtgttggaa cttatgaaaa atcaatcatc
    10141 gaagcgtttg aaaaagcaaa cccagatata aaagtgaaat tggaaaccat cgacttcaag
    10201 tcaggtcctg aaaaaatcac aacagccatc gaagcaggaa cagctccaga cgtactcttt
    10261 gatgcaccag gacgtatcat ccaatacggt aaaaacggta aattggctga gttgaacgac
    10321 ctcttcacag atgaatttgt taaagatgtc aacaatgaaa acatcgtaca agcaagtaaa
    10381 gctggagaca aggcttatat gtatccgatt agttctgccc cattctacat ggcaatgaac
    10441 aagaaaatgt tagaagatgc tggagtagca aaccttgtaa aagaaggttg gacaactgat
    10501 gattttgaaa aagtattgaa agcacttaaa gacaagggtt acacaccagg ttcattgttc
    10561 agttctggtc aagggggaga ccaaggaaca cgtgccttta tctctaacct ttatagcggt
    10621 tctgtaacag atgaaaaagt tagcaaatat acaactgatg atcctaaatt cgtcaaaggt
    10681 cttgaaaaag caactagctg gattaaagac aatttgatca ataatggttc acaatttgac
    10741 ggtggggcag atatccaaaa ctttgccaac ggtcaaacat cttacacaat cctttgggca
    10801 ccagctcaaa atggtatcca agctaaactt ttagaagcaa gtaaggtaga agtggtagaa
    10861 gtaccattcc catcagacga aggtaagcca gctcttgaat accttgtaaa cgggtttgca
    10921 gtattcaaca ataaagacga caagaaagtc gctgcatcta agaaattcat ccagtttatc
    10981 gcagatgaca aggagtgggg acctaaagac gtagttcgta caggtgcttt cccagtccgt
    11041 acttcatttg gaaaacttta tgaagacaaa cgcatggaaa caatcagcgg ctggactcaa
    11101 tactactcac catactacaa cactattgat ggatttgctg aaatgagaac actttggttc
    11161 ccaatgttgc aatctgtatc aaatggtgac gaaaaaccag cagatgcttt gaaagccttc
    11221 actgaaaaag cgaacgaaac aatcaaaaaa gctatgaaac aatagtcctt agttattcta
    11281 taaaaagtag ttttttaaag aacctaagag tgtatacccc cttttccctc tacacagata
    11341 gtgtaagaaa agggggcttt tgtttaaaat gtaagaaact gtcacgaaat taaaatgaag
    11401 ttcttacata agcgaatcat aaaaaatttc attttgattt taaaacagtt caagaaagtc
    11461 aaaaaattat tctatttgaa agagaggtgc cgactgtgaa agtcaataaa atccgtatgc
    11521 gggaaacagt gatttcctac gctttcctag caccagtatt attcttcttt gtcatctttg
    11581 tgttggctcc gatggtgatg ggcttcatta caagtttctt taactactca atgactaaat
    11641 ttgagtttgt aggcttggat aactatatcc gtatgtttaa agatcctgtc tttacaaaat
    11701 ctctgattaa cacagttatt ttggttattg gatctgtacc agttgttgtt ctattctcac
    11761 tctttgtagc atctcagacc tatcatcaaa atgtcattgc cagatccttc taccgtttcg
    11821 tcttcttcct tcctgttgta acgggtagtg ttgccgtgac agttgtttgg aaatggattt
    11881 atgacccact atcagggatt ctaaactttg tccttaagtc aagccacatc atcagccaaa
    11941 acatttcttg gttgggagat aaaaactggg cattgatggc gattatgatt attctcttga
    12001 ccacttcagt tggtcagccc atcatccttt atatcgctgc catggggaat attgacaatt
    12061 cactggttga agcggcgcgt gttgatggtg caactgagtt tcaagttttt tggaagatta
    12121 aatggccaag ccttcttcca acaactcttt atattgcaat catcacaaca attaactcat
    12181 tccagtgttt cgccttgatt cagcttttga catctggtgg tccaaactac tcaacaagta
    12241 ccttgatgta ctacctttac gaaaaagcct tccaattgac agaatacggc tatgccaaca
    12301 caattggtgt cttcttggca gtcatgattg ctatcgtaag ctttgttcaa tttaaagtac
    12361 ttggaaacga cgtagaatac taaagaaagg agacagctat gcaatctaca gaaaaaaaac
    12421 cattaacagc ctttactgtt atttcaacaa tcattttgct cttgttgact gtgctgttca
    12481 tctttccatt ctactggatt ttgacagggg cattcaaatc acaacctgat acaattgtta
    12541 ttcctcctca gtggttccct aaaatgccaa ccatggaaaa cttccaacaa ctcatggtgc
    12601 agaaccctgc cttgcaatgg atgtggaact cagtatttat ctcattggta accatgttct
    12661 tagtctgtgc aacctcatct ctagcaggtt atgtattggc taaaaaacgt ttctatggtc
    12721 aacgcattct atttgctatc tttatcgctg ctatggcact tccaaaacaa gttgtccttg
    12781 taccattggt acgtatcgtc aacttcatgg gaatccacga tactctctgg gcagttatct
    12841 tgcctttgat tggatggcca ttcggtgtct tcctcatgaa acagttcagt gaaaatatcc
    12901 ctacagagtt gcttgaatca gctaaaatcg acggttgtgg tgagattcgt accttctgga
    12961 gtgtagcctt cccgattgtg aaaccagggt ttgcagccct tgcaatcttt accttcatca
    13021 atacttggaa tgactacttc atgcaattgg taatgttgac ttcacgtaac aatttgacca
    13081 tctcacttgg ggttgcgacc atgcaggctg aaatggcaac caactatggt ttgattatgg
    13141 caggagctgc ccttgctgct gttccaatcg tcacagtctt cctagtcttc caaaaatcct
    13201 tcacacaggg tattactatg ggagcggtca aaggataata ctctgcgaaa atcgaatgca
    13261 aactacgtca gcttcacctt gccatactta agtattgcct gtggttagct tcctagtttg
    13321 ttcttcaatt ttcattgagt ataggaaaat caatctatca agatacagaa gtatatttta
    13381 tagatttaga gaatatagaa gttataagtg tctacaaaat ggagggtatg cagttacttt
    13441 atgaagtttt gtcagacact tatcaactta agaatggttt tagttaacta tcagaaacga
    13501 aggaaagagt atgatttttg acgatttgaa aaacatcacc ttttacaaag ggattcatcc
    13561 caatttagac aaggctatcg actacctcta ccaacatcgt aaagattcat tcgaattagg
    13621 aaagtatgag attgatggag ataaagtctt tctagttgtt caggaaaatg tcctcaatca
    13681 agttgagaat aatcaatttg aacaccataa gaactatgca gatttgcatt tgctgataga
    13741 agggcatgaa tattcgagct acggttcacg tatcaaagac gaggcagtag cattcgacga
    13801 agcgagtgac attggctttg ttcattgtta tgaacactac ccactcttat tgggttatca
    13861 caattttgcg attttcttcc caggtgagcc acatcagcca aatggttatg caggcatgga
    13921 agaaaaggtt cgaaaatatc tctttaaaat cttgattgat taaaaatagg atgaattgtt
    13981 tttttgtaaa gctttgataa tactctacca tgaaattgat ctttgtgagg tagagaaatg
    14041 agaataaaat atttaaaaat tggtatcttc taagtatgct gcaagagcta gtttcttgga
    14101 tggacaggga attacagttg atgagatggc ttggataatt aggggcattg tgaatgcatt
    14161 gattggtaga tacataaaat taggtgctta tgcggctaag tatggtatta gtatggcacg
    14221 ctcgatctta agtagggcag ctgcaactgc agcagcaaga gtaggattat cgaccaagat
    14281 ttctggatgg attttacgag tagctgtgaa tgtagctgat gtatatggta attttgccta
    14341 caatattgct gcagcttggg atgcacatga taaaatccct aacaatggtc gtataaactt
    14401 ttaaaatgcg agaatgaaag cactttgtat ttttttattg aatatgttag cttggacagt
    14461 gcttgcaatg ataattcgtg gagggctaga tggatttaat gagcatactt ggagtactat
    14521 tttaattgct tcgctgttcg gggtatatga ttataagccc atagataaaa atagaaaaaa
    14581 gtccaaaaga aaaaagaaaa aatagatttg ttcatggtag ggacttatga aagctttact
    14641 gacaaaaaag aaaacagttt acaaagaaaa atgatggagg agcaaacatg gcacaaaaag
    14701 gagtaagcct tatcaaggca gcatttgata cagacaactt tctcatgcgt tttagtgaga
    14761 aagtcttgga catcgtgaca gccaatcttc tttttgtcgt ctcttgtttg cccatcgtga
    14821 cgattggagt ggctaaaatc agcctctacg agaccatgtt cgaagttaag aagagcagac
    14881 gggtgcctgt ttttaaaatc tatctaagat ctttcaagca aaatctgaaa ctaggtcttc
    14941 agctgggttt aatggagtta ggaattgtgt ttcttaccct ttcagatctc tatcttttct
    15001 ggggtcaaac agctctgccc ttccaattgc tgaaagccat ttgtttaggt attctgattt
    15061 ttcttactat cgtgatgctg gctagttacc ctatcgcggc acgttatgac ctatcttgga
    15121 aagaaattct tcaaaaagga ttgatgttgg ctagttttaa ctttccttgg ttcttcctca
    15181 tgttagccat tcttgtcctc attgtgatgg ttctttatct gtccgccttc agtctactct
    15241 taggtggctc agtcttccta ctttttgggt ttggactatt ggtctttatc cagactggat
    15301 tgatggagaa aattttcgca aaataccaat aggagcttta tttctgaaac tactttcaaa
    15361 ggctccaaac gctattctat aagcgagaaa ctaaaatcta agtgtctata agatattgaa
    15421 agccttttcg ggaaagtgta tactaaagaa gtaaagaaaa atctgcttta gcagaaaata
    15481 aaaataatag gagaaaatct atgtcagatt tgaaaaaata cgaaggtgtc attccagcct
    15541 tctacgcatg ttatgatgat caaggagaag taagcccaga acgtacgcgt gccttggttc
    15601 aatacttcat tgataaaggt gttcaaggtc tttatgtcaa tggttcttct ggtgaatgta
    15661 tctaccaaag cgttgaagat cgcaagttga ttttggaaga agtcatggcg gtagccaaag
    15721 gtaaattgac catcattgct catgttgcct gcaacaatac taaagacagt atggaacttg
    15781 ctcgccatgc tgaaagcttg ggagtagatg ctattgcaac gattccacca atttacttcc
    15841 gcttgccaga atactcagtt gccaaatact ggaacgatat cagttctgca gctccaaaca
    15901 cagactacgt gatttacaac attcctcaat tggcaggggt tgctttgact ccaagccttt
    15961 acacagaaat gttgaaaaat cctcgtgtta tcggtgttaa gaactcttct atgccagttc
    16021 aagatatcca aacctttgtc agccttggtg gggaagacca tatcgtcttt aacggtccag
    16081 atgaacagtt cctaggtggc cgcctcatgg gtgctaaggc tggtatcggt ggtacttatg
    16141 gtgctatgcc agaactcttc ttgaaactca atcagttgat tgcggataag gacctagaaa
    16201 cagcgcgtga attgcagtat gctatcaacg caatcattgg taaactcact tctgctcatg
    16261 gaaatatgta cggtgtcatt aaagaagttt tgaaaatcaa tgaaggcttg aatattggat
    16321 ctgttcgttc accattgaca ccagtgactg aagaagatcg tccagttgta gaagcggctg
    16381 ctgccttgat tcgtgaaacc aaggagcgct tcctctaatc taaaaggagg tatttatgac
    16441 atactacgtt gcaattgata tcggtggaac caacatcaag tatggtttgg ttgatcaaga
    16501 ggggcaactt cttgaatcgc atgaaatgcc aactgaggcg cataagggtg gacctcatat
    16561 cttacaaaag accaaagata tcgtagctag ttatttagaa aaaggcctag tagcaggtgt
    16621 tgccatatct tctgctggga tggtggatcc ggataagggt gagattttct atgctgggcc
    16681 gcaaatccct aactacgcag gcacccagtt caaaaaggaa atcgaagaaa gctttactat
    16741 tccttgtgag attgaaaatg atgtcaactg tgcaggtctt gctgaggcag tatctggttc
    16801 aggcaaggga gcaagtatga cactttgctt gaccattgga acaggtatcg gtggttgctt
    16861 gattatggat aggaaagtct tccatggttt tagcaattca gcctgtgaag tcgggtatat
    16921 gcatatgcag gatggagctt ttcaagactt ggcttctaca acagctttag tgaaatatgt
    16981 agctgaagcc catggagaag atgttgatca gtggaatggc cgtagaattt tcaaagaagc
    17041 cactgaagga aacaaaatct gcatggaagg tattgaccgt atggttgact atctaggaaa
    17101 aggtctggca aatatttgct acgttgccaa tccagaagtg gttattcttg gtggtggtat
    17161 catggggcaa gaggctatcc tcaaacctaa gattcgcaca gccttgaaag aggctttggt
    17221 accaagttta gcagaaaaaa cacgattaga atttgcccat caccaaaata cagcagggat
    17281 gttgggtgca tattatcatt ttaagacaaa acaatcctag tttggctcag ccaaactagg
    17341 attttcttac acgtttttgt ctacgatagc cgttgagttt tttattttcc cagtagctat
    17401 taaagatttt ttccttgctt tcgcgattga tttccaaaaa gtaggcataa atcaaatcga
    17461 taaagaagag cataggaagt tgagcggata ttcgttggat ataggagggt tggctgtggg
    17521 tggctacaag aacagtctct gtataggtct ggctattttt attgggaaca cttgtaaaga
    17581 gtacagtctt tgcccccatc tccttggcat ctaatagact atctaaaata gaaggagttg
    17641 agcctgaaag tgagaagccc agtactagac aattttcatc catgatgctg gttgtccagg
    17701 caaagccgtc ttggtctgtc aaagcttcgc agaccacgcc tagtcgcata aaacgtaatt
    17761 tcatttcacg ggcgacgaga ccagaactcc ctgttccaaa gaagtagata cgctcagcat
    17821 cttcgattag ctgggcaatt cgttctagtt ggatttcgtc aatcaagtct tgtgtttgtt
    17881 ccctcatatt gctataactt ctgaggactc gtttggtcag tggactgtgc ttggagactt
    17941 ggttggcttg attttctgcc tgatgttggt attggaaaat aaattctcgg tagccagtaa
    18001 agccacactt tttagcaaag cgggtcaaag cagcttgaga aatatgtaat ttttgggtga
    18061 cttgttgaga agataaatca tctgtaatcg tttcagcttg caaaaaatag cgagcgattt
    18121 cttgctctag gtctgtcatt tcttcaaaat gtgaatcaat gatagttgcg atatctggtt
    18181 tgtccatagg gaaagctcct ttacatgagt catactggaa gactagatca gggaatagtc
    18241 acgcttcatt ataacacata atataaggat agataaataa aaacgcattt ctgttttaaa
    18301 aacgaaaaaa tcgaaaaagc ttctctcttt tccataattt tctactcaaa ttgtggtaca
    18361 attaagagta agattttaag ttagaaatga gactgatttg tatgagaaaa tttaacagcc
    18421 attcgattcc gattcggctt aatttattgt tttcaatcgt cattttactc tttatgacca
    18481 ttattggtcg tttgttgtat atgcaggttt tgaacaagga tttttacgaa aaaaagctag
    18541 cctcagctag tcagaccaag attacaagca gttcagcccg tggggaaatt tatgatgcta
    18601 gtggaaaacc tttggtagaa aatacgttaa agcaggttgt ttcctttacg cgtagcaata
    18661 aaatgacggc tacagactta aaagaaacag ctaaaaagtt actgacttat gtgagcatca
    18721 gttctccaaa tttgacagaa cgccagctgg cggattacta tttggctgat cctgaaatct
    18781 ataaaaaaac agtggaagct ctcccaagcg agaaacgctt ggattcagat ggaaatcgtc
    18841 tatccgaatc agaactgtat aacaatgcgg tcgatagtgt ccaaacaagt caactaaact
    18901 atacagagga tgaaaagaaa gaaatctatc tttttagtca gttaaatgct gttggaaact
    18961 ttgcgacagg aaccattgct acagatcctc taaatgattc tcaggtggct gttattgcct
    19021 ctatttcaaa ggagatgcct ggcattagta tttcgacttc ttgggataga aaggttttgg
    19081 aaacttccct ttcttctata gttgggagtg tatccagtga aaaagctggt ctcccagcgg
    19141 aagaagcaga agcctatctt aaaaaaggct attctctaaa tgaccgtgta ggaacctcct
    19201 atttggaaaa gcaatatgaa gagaccttac aaggaaaacg atcggtaaaa gaaatccatc
    19261 tggataaata tggcaatatg gaaagcgtgg atacaattga ggaaggtagt aagggaaaca
    19321 atatcaaact gaccattgat ttggccttcc aagatagcgt ggatgctttg ctgaaaagtt
    19381 atttcaattc tgagctagaa aatggtggag ccaagtattc tgaaggtgtc tatgcagtcg
    19441 cccttaaccc aaaaacaggt gcggttttgt ctatgtcagg gattaaacat gacttgaaaa
    19501 caggagagtt gacgcctgat tccttgggaa cggtaaccaa tgtctttgtt ccaggttcgg
    19561 ttgtcaaggc ggcgaccatc agctcaggtt gggaaaatgg agtcttgtca ggaaaccaga
    19621 ccttgacaga ccagtccatt gtcttccaag gttcagctcc catcaattct tggtatactc
    19681 aggcttacgg ttcattccct atcacagcgg tccaagctct ggagtattca tcaaatacct
    19741 atatggtcca aacagcctta ggtcttatgg ggcaaaccta tcaacccaat atgtttgtcg
    19801 gcaccagcaa tctagagtct gctatggaga aactgcgttc aacctttggc gaatatggct
    19861 tgggtactgc gacaggaatt gacctaccag atgaatctac tggatttgtt cccaaagagt
    19921 atagctttgc taattacatt actaatgcct ttgggcagtt tgataactat acgccgatgc
    19981 agttggctca gtatgtagca actattgcaa atgatggtgt tcgtgtggct cctcgtattg
    20041 ttgaaggcat ttatggtaat aatgataagg gaggactggg tgacttgatt cagcaactgc
    20101 aaccgacaga gatgaataag gtcaatatat ccgactccga tatgagcatc ttgcaccaag
    20161 gtttttatca ggttgcccat ggtactagtg aattgacaac tggacgtgcc ttttcaaatg
    20221 gtgccttggt atccattagc ggaaaaacag gtacagccga aagctatgtg gcagatggtc
    20281 agcaagcaac caataccaat gcggtggcct atgccccatc tgataatccc caaatcgctg
    20341 tcgcagtggt ctttcctcat aataccaatc taacaaatgg tgtaggacct tccattgcac
    20401 gtgacattat caatctgtat caaaaatacc atccaatgaa ctagaaagga aattatgctt
    20461 tatccaacac ctattgccaa gttgattgac agttattcta agttaccagg tatcgggatt
    20521 aagacggcta cgcgtctggc cttttatacg attgggatgt ctgctgatga tgtcaatgaa
    20581 tttgcaaaaa atctcctttc tgctaagaga gaattgacat attgttctat ttgtggacgt
    20641 ttgacagacg acgatccttg ttctatctgt actgatccga ctcgtgacca gacaacaatt
    20701 ttagttcttg aggatagtag agatgtggca gccatggaaa atatccaaga ataccatgga
    20761 ctctatcatg tccttcatgg cctcatttct cctatgaatg gtatcagtcc ggacgatatc
    20821 aatctcaaga gccttatgac tcgtcttatg gatagtgagg tttcagaagt gattgtggcg
    20881 actaatgcta cagcggatgg tgaagcgact tccatgtatc tttcacgttt gctcaagccg
    20941 gctggtatca aggttacgcg tctagcacga ggtctcgctg tgggagcgga cattgagtat
    21001 gcggacgaag tgacactctt acgagccatt gaaaatcgga cagagttgta agtgtaggca
    21061 aatttacgaa ctccattcat ttataaaaaa tcaaagaggc tggaaatcgt tcctatcggc
    21121 ctctttttgt atagtgtgat gagtaggatc aggttcaagt tttaaaaaac caagcaaata
    21181 tgatatacta aagagcgagt attctagtag aattaggaca aataatatga aacaaacgat
    21241 tattctttta tatggtggac ggagtgcgga acgcgaagtc tctgtccttt cagctgagag
    21301 tgtcatgcgt gcggtcgatt acgaccgctt cacagtcaag actttcttta tcagtcagtc
    21361 aggtgacttt atcaaaacac aggaatttag tcatgctccg gggcaagaag accgtctcat
    21421 gaccaatgaa accattgatt gggataagaa agttgcacca agtgctatct acgaagaagg
    21481 tgcagtggtc tttccagtcc ttcacgggcc aatgggagaa gatggctctg ttcaaggatt
    21541 cttggaagtt ttgaaaatgc cttacgttgg ttgcaacatt ttgtcatcaa gtcttgccat
    21601 ggataaaatc acgactaagc gtgttctgga atctgctggt attgcccaag ttccttatgt
    21661 ggctatcgtt gaaggcgatg atgtgactgc taaaatcgct gaagtggaag aaaaattggc
    21721 ttatccagtc ttcactaagc cgtcaaacat ggggtctagt gtcggtattt ctaagtctga
    21781 aaaccaagaa gaactccgtc aagccttaga acttgccttc cgatatgata gccgtgtctt
    21841 ggttgagcaa ggagtgaatg cccgtgaaat tgaggttggc ctcttgggta actacgatgt
    21901 caagagcacg ctaccaggag aagttgtcaa ggacgttgcc ttttatgact acgatgccaa
    21961 gtatattgat aacaagatta ctatggatat tcctgccaaa atcagtgatg atgtggtggc
    22021 tgtcatgcgt caaaatgcag aaacagcctt ccgtgccatt ggtggccttg gtctatctcg
    22081 ttgcgatttc ttctatacag ataagggaga gatttttctc aacgagctca ataccatgcc
    22141 aggtttcacc cagtggtcta tgtacccact actttgggac aatatgggga tcagctaccc
    22201 agaactaatc gagcgtttgg ttgaccttgc caaggaaagt tttgacaagc gcgaagcgca
    22261 tttgatataa aatgaaagag agggtagaag ccagaaccat cactgcaagg tgactagagt
    22321 tctcggactt cagccctttt taaaggagta gaaatgaaat taacaatcca tgaaattgcc
    22381 caagttgttg gagccaaaaa tgatatcagt atctttgagg acacccagtt agaaaaagct
    22441 gagtttgata gtcgtttgat tggaactgga gatttatttg tgccacttaa aggtgcgcgt
    22501 gatggccatg actttattga aacagccttt gaaaatggtg cagcagtaac cttgtctgag
    22561 aaagaggtct caaatcatcc ttacattcta gtagatgatg ttttgacagc ctttcaatcc
    22621 ctagcatcct actatcttga aaaaacgact gttgatgtct ttgctgttac aggttcaaat
    22681 ggcaagacaa cgactaagga tatgttggcg catttactgt caacaagata caagacctac
    22741 aaaacacaag gcaattacaa taacgagatt ggccttcctt acacagttct tcatatgcct
    22801 gaagggacag aaaagttggt cttggagatg gggcaggatc acttgggaga tattcatctc
    22861 ttgtctgaac tggctcgtcc aaaaacagcc atcgtgacct tggttggaga agctcatttg
    22921 gcctttttca aagatcgttc tgagattgct aaaggaaaaa tgcaaattgc ggacggaatg
    22981 gcttcaggtt ccttgctttt agcgccggct gaccctatcg tagaggacta tttgccaact
    23041 gataaaaaag tggttcgttt tgggcaaggg gcagagctgg aaattactga cttggttgag
    23101 cgcaaagata gtctgacctt caaggccaat ttcttagagc aagcccttga tttgccagta
    23161 actggtaagt acaatgctac caatgctatg attgcatcct atgttgccct acaagaagga
    23221 gtttcagagg agcaaatccg tttggccttc caaggtcttg aattgacgcg taatcgtact
    23281 gagtggaaga aagcagccaa tggagcagat atcctgtcag acgtatataa tgccaatcca
    23341 actgctatga agctgatttt agagactttc tctgccattc cagccaatga aggtggcaag
    23401 aaaattgcag tgttggcgga tatgaaggag cttggtgacc agtctattca actccataac
    23461 cagatgattt tgagcctttc gccagatgtg cttgataccg ttattttcta tggagaagac
    23521 attgctgaat tagcccaatt ggccagtcaa atgttcccaa ttggccacgt ttactacttc
    23581 aagaaaacag aagaccaaga ccaatttgaa gacctagtca agcaggtcaa ggaaagcctc
    23641 agtgccaatg atcaaatctt gctcaagggc tctaactcta tgaacctagc catgttggta
    23701 gaaagtttag aaaatgaaac caagtgattt tgttaagtat ctgcaaagaa tgattgccct
    23761 tacagatact ggcttaacct ttacaaaaga tccttttgac cgtgagcgct acgaggactt
    23821 gcgaagtctg ttatctgaaa tgttgaatca gggatcagac ctggatgcag aagaagtagc
    23881 agaagtcttg aaaccaactt cagcttatgc gactccctta atggacgtcc gtgcttggat
    23941 tgttgaggat gagaagattt gtctggttag gggacaagga gaggatagtt gggctttgcc
    24001 aggtggcttt ggtgaagtcg gctattctcc aactgaaaat attctcaagg aaattgaaga
    24061 agaaaccggt tttaaagcca aagttgaaag actgctagct gtttttgata ccaatcgttt
    24121 ccaactacag agcaaacaat atgcaaagtt tgtttttgaa tgtaagcttc tcgatggaca
    24181 attccaagaa aatcaagaaa tcgctgacct tcaatttttt gcaattgacc aactgccgaa
    24241 tttatctgaa aaacgcatta ccaaggagca aatagagctt ctttggcagg tttatcaagg
    24301 tcagagggag caatatcttg actaagaaga tgattatcgt atttctaaat tcatttttct
    24361 taagtagcat ggtataataa aatgcaggaa aattttgaat catgaggaag actagatgaa
    24421 tttatgggat attttcttta cgactcaggc aaccgagccg cccaaatttg accttttttg
    24481 gtatgttagc ctatttacgc tcttagcctt aaccttttat acagcccatc gctatcgtga
    24541 aaagaaggtt taccaacgat ttttccaaat cttgcagact gttcagttaa tccttcttta
    24601 tggttggtac tgggtcaatc atatgccact gtcagaaagc ctaccctttt accattgccg
    24661 tatggctatg tttgtggtac tcttgcttcc tggtcagtcc aaatataaac aatactttgc
    24721 attattggga acatttggga cattagcagc ctttgtttat ccagtgccag atgcttaccc
    24781 ttttccacat atcaccattc tatcctttat ctttggtcat ttagcactct tggggaactc
    24841 tctagtttat ctattgagac agtataatgc gcgattgctg gatgtgaagg gaatttttct
    24901 catgaccttt gccctaaatg ccttgatttt tgtggtcaat ttggtgacag gtggcgatta
    24961 cggatttttg acaaaaccgc cattggttgg ggatcacggt ctagtagcta attatttact
    25021 tgtttcaatt gtgctggtag ctactatcag tttgactaag aaaatcttag aattcttttt
    25081 agctcaagaa gcagaaaaaa tgattgcaaa ggaagcttaa cacagagctt tcttttttgc
    25141 tcttagagag tttttacaag cagcttataa aataagaatt tctgaataga caaactcaaa
    25201 aaatggctgg gaaatttagg aaaaaagcaa gcacgattaa attttttgtg ttataatatt
    25261 ttgtgaatag ctatgcctat gtttagctat ggaataatac gaagtgcgaa acttggaaga
    25321 tagagaggaa gcgatgtaat ggctagagaa ggctttttta caggtctaga tattggaaca
    25381 agctctgtca aggtgcttgt ggccgagcag agaactggtg aattaaatgt aattggcgtg
    25441 agtaatgcca aaagtaaagg tgtaaaggat ggaattattg ttgatattga tgcagcagca
    25501 actgctatca agtcagccat ttcccaagcg gaagaaaagg caggcatttc gattaaatca
    25561 gtaaatgtcg gcttgcctgg taatcttttg caggtagaac caactcaggg gatgattcca
    25621 gtaacatctg atactaagga aattacggat caagatgttg aaaatgttgt caaatcagct
    25681 ttgacaaaga gtatgacacc tgaccgtgaa gtcattacct ttattcctga agaatttatt
    25741 gtggatggtt tccaagggat tcgtgaccca cgtggcatga tgggggttcg ccttgaaatg
    25801 cgtggtttgc tttatacagg acctcgtact atcttgcaca atttgcgtaa gacggttgag
    25861 cgtgcaggtg ttcaggttga aaatgttatc atttcaccac tagcaatggt tcagtctgtt
    25921 ttgaacgaag gggaacgtga atttggtgct acagtgattg atatgggggc aggtcaaacg
    25981 actgtcgcta caatccgtaa tcaagaactc cagttcacac atattctcca agaaggtgga
    26041 gattatgtaa ctaaagatat ctccaaggtt ttgaaaacct ctcgcaaatt agcggaaggc
    26101 ttgaaactga attacgggga agcctatccg cctcttgcaa gcaaagaaac cttccaagta
    26161 gaggttattg gagaagtaga agcagtcgaa gtgacggaag cctacttgtc agaaattatt
    26221 tctgcacgaa tcaagcacat ccttgaacaa atcaagcaag aattagatag aaggcgtcta
    26281 ttggacctcc ctggtggtat tgtcttaatc ggtgggaatg ccattttacc aggtatggtt
    26341 gagcttgctc aggaagtctt tggcgtccgt gtcaagcttt atgttccaaa tcaagttggt
    26401 atccgtaatc cagcctttgc gcatgtgatt agtttatcag aatttgcggg tcaattaaca
    26461 gaagttaatc ttttggctca gggagcgata aaaggtgaga atgacttaag tcatcagcca
    26521 attagttttg gtgggatgct gcaaaaaaca gctcagtttg tacaatcaac gcctgttcaa
    26581 ccagctcctg ctccagaagt agagccggtg gcgcctacag aaccaatggc ggatttccaa
    26641 caagcttcac aaaataaacc gaaattagca gatcgtttcc gtggcttgat cggaagcatg
    26701 tttgacgaat aaagaggaaa aataaattat gacattttca tttgatacag ctgctgctca
    26761 aggggcagtg attaaagtaa ttggtgtcgg tggaggtggt ggcaatgcca tcaaccgtat
    26821 ggtcgacgaa ggtgttacag gcgtagaatt tatcgcagca aacacagatg tacaagcatt
    26881 gagtagtaca aaagctgaga ctgttattca gttgggacct aaattgactc gtggtttggg
    26941 tgcaggaggt caacctgagg ttggtcgtaa agccgctgaa gaaagcgaag aaacactgac
    27001 ggaagctatt agtggtgccg atatggtctt catcactgct ggtatgggag gaggctctgg
    27061 aactggagct gctcctgtta ttgctcgtat cgccaaagat ttaggtgcgc ttacagttgg
    27121 tgttgtaaca cgtccctttg gttttgaagg aagtaagcgt ggacaatttg ctgtagaagg
    27181 aatcaatcaa cttcgtgagc atgtagacac tctattgatt atctcaaaca acaatttgct
    27241 tgaaattgtt gataagaaaa caccgctttt ggaggctctt agcgaagcgg ataacgttct
    27301 tcgtcaaggt gttcaaggga ttaccgattt gattaccaat ccaggattga ttaaccttga
    27361 ctttgccgat gtgaaaacgg taatggcaaa caaagggaat gctcttatgg gtattggtat
    27421 cggtagtgga gaagaacgtg tggtagaagc ggcacgtaag gcaatctatt caccacttct
    27481 tgaaacaact attgacggtg ctgaggatgt tatcgtcaac gttactggtg gtcttgactt
    27541 aaccttgatt gaggcagaag aggcttcaca aattgtgaac caggcagcag gtcaaggagt
    27601 gaacatctgg ctcggtactt caattgatga aagtatgcgt gatgaaattc gtgtaacagt
    27661 tgtcgcaacg ggtgttcgtc aagaccgcgt agaaaaggtt gtggctccac aagctagatc
    27721 tgctactaac taccgtgaga cagtgaaacc agctcattca catggctttg atcgtcattt
    27781 tgatatggca gaaacagctg aattgccaaa acaaaatcca cgtcgtttgg aaccaactca
    27841 ggcatctgct tttggtgatt gggatcttcg ccgtgaatcg attgttcgta caacagattc
    27901 agtcgtttct ccagtcgagc gctttgaagc cccaatttca caagatgaag atgaattgga
    27961 tacacctcca tttttcaaaa atcgttaagt aaatgaatgt aaaagaaaat acagaacttg
    28021 tttttcgaga agttgcagag gctagtctga gtgctcatcg agagagtggt tcggtctctg
    28081 tcattgcagt taccaagtat gtagatgtac cgacagcgga agccttgctt ccgctaggtg
    28141 ttcatcatat cggtgaaaat cgtgtagata agtttctgga aaaatatgaa gctttaaaag
    28201 atcgagatgt gacttggcat ttgattggta ccttgcaaag acgtaaggtg aaagatgtca
    28261 ttcaatacgt tgattatttc catgcattgg actcagtaaa gctagcaggg gaaattcaaa
    28321 aaagaagtga ccgagtcatc aagtgtttcc ttcaagtaaa tatttctaaa gaagaaagca
    28381 aacacggttt ttcgagagag gaactgctgg aaatcttgcc agagttagcc agactagata
    28441 agattgaata tgttggttta atgacgatgg caccttttga ggctagcagt gagcagttga
    28501 aagagatttt caaggcgacc caagatttac aaagagaaat tcaagagaaa caaattccaa
    28561 atatgcctat gaccgagtta agtatgggaa tgagtcgtga ttataaagaa gcgattcaat
    28621 tcggttccac ttttgttcgt ataggtacat cattttttaa gtaggagaga accatgtctt
    28681 taaaagatag attcgataga tttatagatt attttacgga ggatgaggat tcaagtctcc
    28741 cttatgaaaa aagagatgag cctgtgttta ctccagtaaa ttcttcacag gaaccggctc
    28801 tcccaatgaa tcaaccttca cagtcggctg gtacaaaaga gaacaatatc accagacttc
    28861 atgcaagaca acaggaattg gcaaatcaga gtcagcgtgc aacggataag gtcattatag
    28921 atgttcgtta tcctagaaaa tatgaggatg caacagaaat tgttgattta ttggcaggaa
    28981 acgaaagtat cttgattgat tttcagtata tgacagaggt gcaggctcgt cgttgtttgg
    29041 actatttgga tggagcttgt catgttttag ctggaaattt gaaaaaggta gcttctacca
    29101 tgtatttgtt gacaccagtg aatgttattg taaatgttga agatatccgt ttaccagatg
    29161 aagatcaaca gggtgagttc ggttttgata tgaagcgaaa tagagtacga taatgatttt
    29221 tttaattcgt atgatttata atgcagtgga tatttactcc ctgattttgg tagccttcgc
    29281 tgtcatgtct tggtttccag gtgcctacga atccagttta ggtcgttgga ttgtagcgtt
    29341 ggtgaaacca gtgcttgctc ccttgcaacg cctgccttta cagatagcgg gtcttgattt
    29401 atctgtttgg gtcgcgattg ttttggttcg atttttagga gaaaacctag tgcgttttct
    29461 ggcgatgata ggatgaataa agggatttat tagcatttct ccatagaaga tcgtccattt
    29521 cttgacaagg gaatggaatg gataaagaag gtagaagata gctatgctcc ttttttaact
    29581 ccttttatca atcctcatca ggagaagcta ttaaagattt tggccaaaac ctatggtctt
    29641 gcttgtagca gtagtgggga attcgtctcg agtgagtatg ttcgagtttt attataccca
    29701 gattatttcc aaccagagtt ttcagatttt gaaatatctc tccaggaaat tgtgtattcc
    29761 aataaatttg aacatttaac gcatgctaag attttaggga cagtcatcaa tcaattaggg
    29821 attgaacgga aactttttgg agatatccta gtagatgaag aacgggcgca gattatgatt
    29881 aatcagcagt ttcttcttct ctttcaagat ggactaaaga aaattggtcg tatacctgtt
    29941 tcgctggagg aacgtccttt caccgagaaa atagataagc tagaacagta tcgagaactg
    30001 gatttatctg tgtctagttt tcgattagat gttcttttat caaatgtttt gaaactatct
    30061 aggaatcaag caaaccagtt gattgaaaag aaacttgtcc aagtaaatta tcatgtggta
    30121 gacaaatcag attacactgt tcaagttgga gacttgatta gtgtgagaaa atttggtcgc
    30181 ttgagattac ttcaagataa gggacaaacg aaaaaagaga agaaaaaaat aaccgtccag
    30241 ttattattaa gtaagtgagg aatagaatgc caattacatc attagaaata aaggacaaga
    30301 cttttggaac tcgattcaga ggttttgatc cagaagaagt cgatgaattt ttagatattg
    30361 tggttcgtga ttacgaagat cttgtgcgtg cgaatcatga taaaaatttg cgtattaaga
    30421 gtttagaaga gcgtttgtct tactttgatg aaataaaaga ttcattgagc cagtctgtat
    30481 tgattgctca ggatacagct gagagagtga aacaggcggc gcatgaacgt tcaaacaata
    30541 tcattcatca agcagagcaa gatgcgcaac gcttgttgga agaagctaaa tataaggcaa
    30601 acgagattct tcgtcaagca actgataatg ctaagaaagt cgctgttgaa acagaagaat
    30661 tgaagaacaa gagccgtgtc ttccaccaac gtctcaaatc tacaattgag agtcagttgg
    30721 ctattgttga atcttcagat tgggaagata ttctccgtcc aacagctact tatcttcaaa
    30781 ccagtgatga agcctttaaa gaagtggtta gcgaagtact tggagaaccg attccagttc
    30841 caattgaaga agaaccaatt gatatgacac gtcagttctc tcaagcagaa atggaagaat
    30901 tacaagctcg tattgaggta gccgataaag aattgtctga atttgaagct cagattaaac
    30961 aggaagtgga agctccaact cctgtagtga gtcctcaagt tgaagaagag cctctgctca
    31021 tccagttggc ccaatgtatg aagaaccaga agtagctcca gtgcatccga caggtccaac
    31081 accagctaca gaaactgttg attcagcacc gggatttgaa gcaccgcaag aatctgttac
    31141 aattttataa gaaatattct gagaacaata tcttatcctt atattcccag cgagcaggag
    31201 atggtgtgag tcctgcattc cctatcgata agattatcct ctcaaaaact caagtctgaa
    31261 tctagtaaga tttgacgttc cccacgttac gggataagag ggagaaagac taaaactttt
    31321 tccgaataaa ggtggtacca cgattttcgt cctttttgga agttgtggtt tttaatttgt
    31381 tattatttat aaaggagata ccatgaaact caaagacacc cttaatcttg ggaaaactga
    31441 attcccaatg cgtgcaggcc ttcctaccaa agagccagtt tggcaaaagg aatgggaaga
    31501 tgcaaaactt tatcaacgtc gtcaagaatt gaaccaagga aaacctcatt tcaccttgca
    31561 tgatggccct ccatacgcta acggaaatat ccacgttgga catgctatga acaagatttc
    31621 aaaagatatt attgttcgtt ctaagtctat gtcaggattt tacgcaccat ttattcctgg
    31681 ttgggatact catggtctgc caatcgagca agtattgtca aaacaaggtg tcaaacgtaa
    31741 agaaatggac ttggttgagt acttgaaact ttgccgtgag tacgctcttt ctcaagtaga
    31801 taaacaacgt gaagatttta aacgtttggg tgtttctggt gactgggaaa atccatatgt
    31861 gaccttgact cctgactatg aagcagctca aattcgtgta tttggtgaga tggctaataa
    31921 gggttatatc taccgtggtg ccaagccagt ttactggtca tggtcatctg agtcagccct
    31981 tgctgaagca gagattgaat accatgactt ggtttcaact tccctttact atgccaacaa
    32041 ggtaaaagat ggcaaaggag ttctagatac agatacttat atcgttgtct ggacaacgac
    32101 tccatttacc atcacagctt ctcgtggttt gacggttggt gcagatattg attacgtttt
    32161 ggttcaacct gctggtgaag ctcgtaagtt tgtcgttgct gctgaattat tgactagctt
    32221 gtctgagaaa tttggctggg ctgatgttca agttttggaa acttaccgtg gccaagaact
    32281 caaccacatc gtaacagaac acccatggga tacagctgta gaagagttgg taattcttgg
    32341 tgaccacgtt acgactgact ctggtacagg tattgttcat acagcccctg gttttggtga
    32401 ggacgattac aatgttggta ttgctaataa tcttgaagtc gcagtgactg ttgatgaacg
    32461 tggtatcatg atgaagaatg ctggtcctga atttgaaggt caattctatg aaaaggtagt
    32521 tccaactgtg attgaaaaac ttggtaacct ccttcttgcc caagaagaaa tctctcactc
    32581 atatccattt gactggcgta ctaagaaacc aatcatctgg cgtgcagttc cacaatggtt
    32641 tgcctcagtt tctaaattcc gtcaagaaat cttggacgaa attgaaaaag tgaaattcca
    32701 ctcagaatgg ggtaaagtcc gtctttacaa tatgatccgt gaccgtggtg actgggttat
    32761 ctctcgtcaa cgtgcttggg gtgttccact tcctatcttc tacgctgaag atggtacagc
    32821 tatcatggta gctgaaacta ttgaacacgt agctcaactt tttgaagaac atggttcaag
    32881 catttggtgg gaacgtgatg ccaaagacct cttgccagaa ggatttactc atccaggttc
    32941 accaaacggc gagttcaaaa aagaaactga tatcatggac gtttggtttg actcaggttc
    33001 atcatggaat ggagtggtgg taaaccgtcc tgaattgact tacccagccg acctttacct
    33061 agaaggttct gaccaatacc gtggttggtt taactcatca cttatcacat ctgttgccaa
    33121 ccatggcgta gcaccttaca aacaaatctt gtcacaaggt tttgcccttg atggtaaagg
    33181 tgagaagatg tctaaatctc ttggaaatac cattgctcca agcgatgttg aaaaacaatt
    33241 cggtgctgaa atcttgcgtc tctgggtaac aagtgttgac tcaagcaatg acgtgcgtat
    33301 ctctatggat attttgagcc aagtttctga aacttaccgt aagattcgta acactcttcg
    33361 tttcttgatt gccaatacat ctgactttaa cccagctcaa gatacagtcg cttacgatga
    33421 gcttcgttca gttgataagt acatgacgat tcgctttaac cagcttgtca agatcattcg
    33481 tgatgcctat gcagactttg aattcttgac gatctacaag gccttggtga actttatcaa
    33541 cgttgacttg tcagccttct accttgattt tgccaaagat gttgtttaca ttgaaggtgc
    33601 caaatcactg gaacgccgtc aaatgcagac tgtcttctat gacattcttg tcaaaatcac
    33661 caaactcttg acaccaatcc ttcctcacac tgcggaagaa atttggtcat atcttgagtt
    33721 tgaaacagaa gacttcgtcc aattgtcaga attaccagag gctcaaactt ttgctaatca
    33781 agaagaaatc ttggatacat gggcagcctt catggacttc cgtggacaag ctcaaaaagc
    33841 cttggaagaa gctcgtaatg caaaagtaat cggtaaatca cttgaagcac acttgacagt
    33901 ttatccaaac gaagttgtga aaactctact cgaagcagta aacagcaatg tggctcaact
    33961 tttgatcgtg tcagacttga ccatcgcaga aggaccagct ccagaagctg cccttagctt
    34021 cgaagatgta gccttcacag ttgaacgcgc tgcaggtgaa gtatgtgacc gttgccgtcg
    34081 tattgaccca acaacagcag aacgtagcta ccaggcagtt atctgtgacc actgtgcaag
    34141 tatcgtagaa gaaaactttg cagatgcagt cgcagaagga tttgaagaga aataagattg
    34201 aaaagtctag gcaaaattca atttgagaag aaaagacaac taattttata gtctattaaa
    34261 cgcattgtat cacgtttttg aacacctgat atgatgcgtt ttttattttt aaaatttgca
    34321 aggtgtgact ttttatactc atactcaatg aaaatcaaaa agcaaactag gaagctagcc
    34381 gcaggctgct caaaacactg ttttgaggtt gtagataaga ctgacgaagt cagtaacata
    34441 tatatggtaa ggcgacgctg acgtggtttg aagagatttt cgaagagtat caacaagaat
    34501 caaagagaaa cttagcaagc taacagtagt aagataaaat aggaatttga tattagggat
    34561 aagattggta aatagtgtaa tatttttaca acaataaatt tatatagtta tttctggttt
//
LOCUS       DBEJKC010000018        34530 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.018, whole genome shotgun sequence.
ACCESSION   DBEJKC010000018 DBEJKC010000000
VERSION     DBEJKC010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34530
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.018"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..1040)
                     /locus_tag="ACL3G6_000871"
     CDS             complement(<1..1040)
                     /locus_tag="ACL3G6_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HGR0545430.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTVVRAEEAPVAKQSQAER
                     DYDAAMKKSEAAKKEYEEAKKDLEEAKAAQKKYEDDQKKTEEKAKLVQKADEERQKAN
                     VAVQKAYLKLREAQEQLNKSPNNKKNAAQQKLKDALAHIDEVTLKQKEAEANFNKEQA
                     KVVPEADKLAETKKKAEQAEKKEPELAKKVAEAKAKAEEAEKKAVEAKQKVDAEKYAL
                     EAKIAELEYEVQGLEKELKEIDESDSEDYIKEGLRAPLQSKLDAKKAKLSKLEELSDK
                     IDELDAEIAKLEKDVEDFKNSDGEQAEQYLVAAKKDLDAKKAELENTEADLKKAVDEP
                     ETPAPAPKPAPAP"
     gene            complement(1329..1607)
                     /locus_tag="ACL3G6_000872"
     CDS             complement(1329..1607)
                     /locus_tag="ACL3G6_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545431.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKIISCCIVARDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKSVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            complement(1592..1831)
                     /locus_tag="ACL3G6_000873"
     CDS             complement(1592..1831)
                     /locus_tag="ACL3G6_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545432.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            complement(2288..2485)
                     /locus_tag="ACL3G6_000874"
     CDS             complement(2288..2485)
                     /locus_tag="ACL3G6_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545433.1"
                     /translation="MKHFFAGIGEIKLVGYLLYICVGLALLFHIYVIGSELSFVKIVL
                     SILGVIFVSMLTIARIYRTFL"
     gene            complement(2964..3692)
                     /locus_tag="ACL3G6_000875"
     CDS             complement(2964..3692)
                     /locus_tag="ACL3G6_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545434.1"
                     /translation="MNNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSSWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKAKEYELFKNSK"
     gene            complement(3689..4021)
                     /locus_tag="ACL3G6_000876"
     CDS             complement(3689..4021)
                     /locus_tag="ACL3G6_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGR0545435.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICVALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGKIAYCIGYGALNRGCDISGNPYPWD
                     GFISATVR"
     gene            complement(4077..4979)
                     /locus_tag="ACL3G6_000877"
     CDS             complement(4077..4979)
                     /locus_tag="ACL3G6_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545436.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHLLVSNLQLNLEIPLDFVVSTSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEMSISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            complement(4998..5180)
                     /locus_tag="ACL3G6_000878"
     CDS             complement(4998..5180)
                     /locus_tag="ACL3G6_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545437.1"
                     /translation="MGIKMEKIFVIIFFVCLFISSIIFLAYDFVSEEIKKLIIWMNVV
                     FLILIIAMIIYPKLRK"
     gene            complement(5187..5561)
                     /locus_tag="ACL3G6_000879"
     CDS             complement(5187..5561)
                     /locus_tag="ACL3G6_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HGR0545438.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            complement(5938..6915)
                     /locus_tag="ACL3G6_000880"
     CDS             complement(5938..6915)
                     /locus_tag="ACL3G6_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545439.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLISFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINNPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYIGIKHVSIRR"
     gene            complement(7230..8288)
                     /locus_tag="ACL3G6_000881"
     CDS             complement(7230..8288)
                     /locus_tag="ACL3G6_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545440.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPFSVFTFMFSYILLFVQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            complement(8445..8690)
                     /locus_tag="ACL3G6_000882"
     CDS             complement(8445..8690)
                     /locus_tag="ACL3G6_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545441.1"
                     /translation="MGIYGRKTIAMKHFFAGIGEIHFLLFLLYLSMSASPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            complement(8671..8796)
                     /locus_tag="ACL3G6_000883"
     CDS             complement(8671..8796)
                     /locus_tag="ACL3G6_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545442.1"
                     /translation="MATITNALNIAATVAEVFSLGGAIAYGLDIVDGKFDGYLWA"
     gene            complement(9170..9382)
                     /locus_tag="ACL3G6_000884"
     CDS             complement(9170..9382)
                     /locus_tag="ACL3G6_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545443.1"
                     /translation="MLIVLISVIVALLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQTK"
     gene            complement(9536..9970)
                     /locus_tag="ACL3G6_000885"
     CDS             complement(9536..9970)
                     /locus_tag="ACL3G6_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545444.1"
                     /translation="MGGAYLSKSACQGICAALAMSPGTFIALTGAAVLTKKLINYIKV
                     GGLGGWLIGAAAGVLALIFLIKICVDTTIKVLLNRIFKASKVMKRRIFSLFVLDLMVY
                     IFLGYVLVIQKDVYLFSILIIFSNFSVPFIREKEYELFKNKK"
     gene            complement(10009..10347)
                     /locus_tag="ACL3G6_000886"
     CDS             complement(10009..10347)
                     /locus_tag="ACL3G6_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="HGR0545445.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            10813..11676
                     /locus_tag="ACL3G6_000887"
     CDS             10813..11676
                     /locus_tag="ACL3G6_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0545446.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYIRQHGAGELSDHAEQVVKKLWRKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVEIYYQAKER"
     gene            complement(11889..12281)
                     /locus_tag="ACL3G6_000888"
                     /pseudo
     CDS             complement(11889..12281)
                     /locus_tag="ACL3G6_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269502.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase domain-containing
                     protein"
     gene            complement(12298..13104)
                     /locus_tag="ACL3G6_000889"
     CDS             complement(12298..13104)
                     /locus_tag="ACL3G6_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0545447.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(13311..13952)
                     /locus_tag="ACL3G6_000890"
     CDS             complement(13311..13952)
                     /locus_tag="ACL3G6_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0545448.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(13949..16057)
                     /locus_tag="ACL3G6_000891"
     CDS             complement(13949..16057)
                     /locus_tag="ACL3G6_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGR0545449.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(16109..16360)
                     /locus_tag="ACL3G6_000892"
     CDS             complement(16109..16360)
                     /locus_tag="ACL3G6_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGR0545450.1"
                     /translation="MVCGILATTNALAVWVEGGQWNYGVGWTGTFGYSDYLHSTRYHT
                     ATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            16804..17130
                     /locus_tag="ACL3G6_000893"
                     /pseudo
     CDS             16804..17130
                     /locus_tag="ACL3G6_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            complement(17182..17769)
                     /locus_tag="ACL3G6_000894"
     CDS             complement(17182..17769)
                     /locus_tag="ACL3G6_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGR0545451.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQKLVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            18011..18682
                     /gene="sdaAB"
                     /locus_tag="ACL3G6_000895"
     CDS             18011..18682
                     /gene="sdaAB"
                     /locus_tag="ACL3G6_000895"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HGR0545452.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            18691..19563
                     /gene="sdaAA"
                     /locus_tag="ACL3G6_000896"
     CDS             18691..19563
                     /gene="sdaAA"
                     /locus_tag="ACL3G6_000896"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HGR0545453.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            19585..20217
                     /locus_tag="ACL3G6_000897"
     CDS             19585..20217
                     /locus_tag="ACL3G6_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0545454.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            20267..20524
                     /locus_tag="ACL3G6_000898"
     CDS             20267..20524
                     /locus_tag="ACL3G6_000898"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545455.1"
                     /translation="MKIKEQTRKLAAGCSKHCFKIVDGTDEVSSKHCFKVVDGTDEVS
                     SKHCFEVADRTDEVSSKHCFKVVDGTDEVSNHIRQGDVDVI"
     gene            complement(20610..22460)
                     /locus_tag="ACL3G6_000899"
     CDS             complement(20610..22460)
                     /locus_tag="ACL3G6_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HGR0545456.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(22502..23659)
                     /locus_tag="ACL3G6_000900"
     CDS             complement(22502..23659)
                     /locus_tag="ACL3G6_000900"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0545457.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKEDIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVINNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNML"
     gene            23717..24883
                     /locus_tag="ACL3G6_000901"
     CDS             23717..24883
                     /locus_tag="ACL3G6_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HGR0545458.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            25022..25348
                     /locus_tag="ACL3G6_000902"
     CDS             25022..25348
                     /locus_tag="ACL3G6_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGR0545459.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEHLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            25335..25928
                     /locus_tag="ACL3G6_000903"
     CDS             25335..25928
                     /locus_tag="ACL3G6_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HGR0545460.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYATRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            25921..26832
                     /locus_tag="ACL3G6_000904"
     CDS             25921..26832
                     /locus_tag="ACL3G6_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HGR0545461.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            26895..27959
                     /locus_tag="ACL3G6_000905"
     CDS             26895..27959
                     /locus_tag="ACL3G6_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6574 domain-containing protein"
                     /protein_id="HGR0545462.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIANLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLKSPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(28031..28891)
                     /locus_tag="ACL3G6_000906"
     CDS             complement(28031..28891)
                     /locus_tag="ACL3G6_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 family protein"
                     /protein_id="HGR0545463.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(29013..29999)
                     /locus_tag="ACL3G6_000907"
     CDS             complement(29013..29999)
                     /locus_tag="ACL3G6_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HGR0545464.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(30271..31746)
                     /locus_tag="ACL3G6_000908"
     CDS             complement(30271..31746)
                     /locus_tag="ACL3G6_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0545465.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(31830..32753)
                     /locus_tag="ACL3G6_000909"
     CDS             complement(31830..32753)
                     /locus_tag="ACL3G6_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0545466.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(32767..33696)
                     /locus_tag="ACL3G6_000910"
     CDS             complement(32767..33696)
                     /locus_tag="ACL3G6_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0545467.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(34015..34365)
                     /locus_tag="ACL3G6_000911"
     CDS             complement(34015..34365)
                     /locus_tag="ACL3G6_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545468.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKALTDDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTEAELI
                     DNLKEVIAKLKANA"
BASE COUNT        10901 a         7131 c         5676 g        10822 t
ORIGIN      
        1 ggagctgggg ctggtttagg agccggagct ggagtttctg gctcatcaac tgctttctta
       61 aggtcagctt cagtattttc taattcagct tttttagcat ctaagtcttt tttagctgca
      121 acaagatatt gttcagcttg ctcaccgtct gagtttttga aatcttctac atctttttca
      181 agttttgcaa tttcagcgtc taactcatca atcttatcac tcaactcttc aagttttgat
      241 agtttagctt ttttggcatc caatttagat tgaagaggag cacggagacc ttctttaata
      301 taatcttctg agtcagactc atcaatctct ttgagctctt tttctagtcc ctgaacttca
      361 tattccaact cagcgatttt agcttcaaga gcatattttt cagcatccac tttttgtttg
      421 gcttcaacag cttttttctc agcttcttct gcttttgctt tagcttctgc tactttttta
      481 gcaagttctg gttctttttt ttcagcctgt tctgcttttt tcttagtctc agctaactta
      541 tctgcttcag gaactacttt tgcttgttcc ttattgaaat tcgcttccgc ctctttttgt
      601 tttaatgtta cctcatcaat atgagctaat gcatctttta atttctgttg agcggcattt
      661 ttcttattgt ttggactttt gttcaattgt tcttgtgctt ctcggagttt taaatacgcc
      721 ttttgaactg ccacattcgc tttttgacgc tcttcatccg ctttttgaac aagctttgct
      781 ttctcttcag ttttcttttg atcgtcttca tattttttct gagcagcttt tgcttcttct
      841 aaatctttct tagcttcttc gtattctttc ttagcagctt cagatttttt cattgctgca
      901 tcatagtctc tctcagcttg agactgctta gctacgggag cttcttctgc tcttacaaca
      961 gtaggctgag acgcaacaaa accagcccct aagatagcga cgctggctag acttgttaaa
     1021 atcatttttt tcttattcat ctaaatttac ctcttttctg atagtcattt ttagactata
     1081 cttatattaa gtatactccc cccgtaaata tttgtcaaat gttttatatt acatttttat
     1141 tacaaatttc tatatcataa gcttctactc caaaaaatag ataaagatac tacttttgcc
     1201 cttttcgatt ctctttttaa acatagcatc atcttccttc attcctataa aaacatttcc
     1261 gatgagagag cttgtttttt aatttcgtta aacaacaaaa aacgcaagct taagcctgcg
     1321 gacaatcttt atagccattt catttctttc acatctgttt tacgaacttt agcatatttc
     1381 ttagcgcttg taaaatgtag agtaactgat ttaaatactc cgcttttgtc tcttcgtaaa
     1441 cctaaaactg cggatctttt atttttatcc tcaaaaaata tgacgtccaa tttcatagta
     1501 tttttagata aatccctagc tacgatgcaa caacttatta ttttagaata gaaaatatca
     1561 ccgataaact catataaaga tatcctttcg attacatcat tgtacatagg atatttctaa
     1621 aatcttctaa aataaaaaca ccagcttgaa tagcaggttt tgtttgacta gcataatctc
     1681 gtgtgatttt gtataagtca aataaatgat gtaaatcagt caagcaaaaa ttcactttga
     1741 aaatctctaa atacttataa ttcgttgata cttgacatgt ttttccattg aatctttctt
     1801 gatagtccaa aatacaatca agtaatttca acgacaaact ccatattttc tcaaaataaa
     1861 aaagcacggg gcagttctca ctactgccca aagtggttga ttagagtcgg cttctctaac
     1921 tccctatgtt gtgcttatta ggcttatcgc aagggaacag tttttagctc tgccaagcca
     1981 catagtgtgc ttactactat gtgtccatgt caccatgaat tgccgaacgg tttaacgaga
     2041 aagtatagta gattgaaaca agatgtgaac aaatcgatta ggaaagtcaa attaatttct
     2101 agaaatattt taacagtcat aacggactat tccagattca atctactata ttacttttag
     2161 gtttatccca actcaattat gacatttttt tcaaaagtca atatatctca ctcttttcaa
     2221 cgacaagaaa gaggctgata atcgaccaac ctctgttttt agatacagtt caagtccaaa
     2281 ctattcttta tagaaaagtc cgataaattc gagcaatagt taacatactt acaaatataa
     2341 ctcccaaaat agataacact attttcacaa aactcagttc cgaacctatg acatatatat
     2401 gaaaaagaag ggctagtcct acacatatat acaataagta gccaacaagt tttatctcac
     2461 caattcctgc aaaaaaatgt ttcatgtgac gattctccat ttactccatt aaatcagttt
     2521 tattttagac tatcataaca caatcacctc ttcaataaaa accatttgcg aaatactatt
     2581 ctgaagcatt gatagctcag atttctcaga atagagctgt cctaactatc gagcagctca
     2641 aatacatata tatgagcaat tctaagccta gaattactat aaaataaatg tttccaggct
     2701 attctaagtc tttgactgct taaaatttta cattctgaag gattctaaag ctagaacagc
     2761 tcaaaatcac gagaactaag gtattcgaaa cttcagagta atacaatccc cataggaatt
     2821 ctccattctt attaagcatg attaaaatgt aatcctaaca agtgatcctc gactgtgttt
     2881 gtagcactta gttacctaga taagactatt tccctttatc atatctgatt ttaagccgtt
     2941 ctaagattta acctatgttt ctattacttg ctatttttaa ataattcgta ttcctttgct
     3001 ttgataaatg gaactgaaaa attagaaaaa agaagtaaaa ccgaaaacaa atagcctgct
     3061 ttttgaatca ctaaaagata tcctaaaaat aagtaagcta taacatccaa tgcgaaaaga
     3121 aaaaatattc tcctcttcat taaagtactt gtgtcaaata atctgatgaa taaaaatttt
     3181 atcgtagtat ctacacaaat ttttatcaaa aagataagag ccaatacacg attatcaact
     3241 gtaccgtaaa gaatagatgg aaatatagtt aatataaaac tagaaatctc taaatatttt
     3301 atccaagaag attgagacac cttgcttcta aactgactaa ttttcttata ttcgttagtc
     3361 aatttagtag caaaatcttc cccaattaaa tgaaagattg ctaactctag gataaaaaca
     3421 cttattaata cggtataagt caaaaaactt tctgggaaaa acttattgat taaaatgggg
     3481 aaactcatta acagaatcga atttatggct agacagatag atactatttt atttttcaca
     3541 gaatatagag gtagtgatac tattgagtag ataaaagcta aaaaaataag caaaaaatac
     3601 tccgtgtcat ttataatcgc cctgaatgat aaaaatatat acacccaaca tacgataata
     3661 tgtatttttc gaatcttatc tacattattc atcttactgt cgcagatata aatccatccc
     3721 aaggataagg gttcccgcta atatcacaac ctctattaag agcaccatat ccaatacagt
     3781 aagctatttt tcctgctgct gcaccaataa gccagcctcc aagacctcca accttaatat
     3841 agtttattag ttttttggtt aaaactgcag ctccagctaa tgctataaaa gttcctgaac
     3901 tcatagctaa agctacgcaa attccttgac aagcacgctt gcttaaataa gctcccccat
     3961 caagatacat catttcttct tcatcaatca caacataatt atttggtaat acaagttcca
     4021 tttgttttct cctccttagt tgaaattgtt tcatttgttt tacaaatagg acgaacttaa
     4081 actatctttt tattactcag taataatttc cgagatttca ttttatgata ctctctattc
     4141 atacagaaat caaaattttg ccttaaccaa cttgtataat agaaaaaatc taattgattg
     4201 attctgatga ggtgtatcct aattttatca accttgttgg accagttgtt attgttacta
     4261 atagacattt catacagcag taactcgaca agacctgtac acagaagggt gttatgagaa
     4321 tcttcgattt ttttcaaaat atcctcaaaa agttcactat ccgttaaaaa ggtggattgg
     4381 ttcatcgcat catacagctg aagagacatt aagtcagaat aacttagctc tgatttttgt
     4441 atcttatcct ttaacgtttt cgtcaaatcg ctttcaaacg aatcttcttt ttcccattta
     4501 ttttgattaa aaagaaattc cgtcttatta aaaacgagat gattgatatc cattatagtc
     4561 cagaaaaata ttgtagtaag catgatgatt gcaaaaggaa tttttaaaat aaatactaga
     4621 ataatagcaa tttcaagaat aaaactccat ataatcctag atcttaaatc atcaggcgac
     4681 aaacttttac gatggaatga aaaatagggc gagaacctca catttacttt cttcctgcct
     4741 ataaaaataa aaggaaaaat cgtaataaga gcttctttct tgtacaaatc tttcaatgcg
     4801 tatagtatgt ctaaaactat ttttgataaa atcaaactac agaaagcaag actcgtacta
     4861 accacaaaat caaggggaat ttctagattc aattgcaagt tactcactaa caaatgcaac
     4921 tctagccaca agacaaaaag agggagcatt aataaaaaaa tgattagttt acgtatcata
     4981 attttacagt gtccttatca ttttcttaat tttggataaa ttatcattgc tatgattaaa
     5041 atcaaaaaaa cgacattcat ccaaataatc aactttttta tttcttcgct aacaaaatca
     5101 taggctaaaa aaattatgga tgatataaat agacatacaa aaaaaataat aacaaaaatt
     5161 ttttccattt taatacccat atctagttac cacaaggcgt ttaaatttgg gtctctccta
     5221 tttacatcat tgttggccca gattgttgta atagcatcgc caattgacat ccaagctgca
     5281 aatccattaa tagcagacag tgcaaatcct gccactctat ttgcaactcg taccccaaca
     5341 tatcttgcag ctgctccagc aattgcgctt gtaactcgcc gcaaaccata attacgaata
     5401 taatttctaa ctagactgat tgctcctcca cctaaaacac cattaaaagc tatattaatg
     5461 gctgttgcaa caggccatct cagaatagaa aatcccccat caagatacat catctcttct
     5521 tgctcaagag caacataatt atttggtaat acgagttcca tttattttct ccttttttat
     5581 taagcatagt taggatcgtt tcctaacaag tgatagacga ctgtgttttt atcacttagc
     5641 tacctagata agatatcctt tctctacctt atttgttttt ataggttacc taaggtttaa
     5701 aatcaattat tgtttgaaac ttaacagttc taaaccacta gcaataaatg attgcgaact
     5761 cactaatact atttcaaaat ttattttttt tgacttagta acgcaattcc aattagcaat
     5821 acacctaata taaataaaag tatttcccaa aatttattct cagttttaat aagtggaata
     5881 agatacatac tgactaatat gcaacttgcc cctataatgg caaatattat tctagtttta
     5941 tctcctaatt gaaacatgtt tgatccctat atacacttca agcaaaagtt ggatttctga
     6001 aatggctaaa gataaagata atggttgcga gctatttaaa ctatcatcaa tattctgctc
     6061 gattaaaaca aagtctggtc ttacctctaa aattttcttt aacattgatt catatttatt
     6121 tttttcatta taatgccgta aatatagatt taattttata acatccaaca taccataaag
     6181 tgatattgga ttatttattt ttttaaatcg cttaacttct aataaatcaa tttgttcacg
     6241 cacactctct gaaagatatg gcttgattaa actgatataa gataaagcca cgcatggcaa
     6301 ctcagatttt gattgcaatt tccaaatttc atgataatcc tgaagattaa actcacaatt
     6361 cttcttagat tccagtattg ttagtacctt tgattttaac agaaataatt gttgattctc
     6421 aattctataa agtttttgta ctaatgctat gataatagaa aatgaaataa gaggcaaaag
     6481 caacggtttg tcatacacaa aagtaaagaa aaaatagtat gaaattagtg ttgtaaagta
     6541 caagaagtag taaaatttaa acagattctt agttgtttga ctctccttat aaaacactgc
     6601 tattcctgga ctaaatccca ttagttggtg aaagagaatt cgatagtatt tcctagctcc
     6661 tataatgatc acaaatataa aataaaaata aattggtctt aatttacaaa agattgagga
     6721 aactagtaat agcaaagtat gtaagcattg agacaaaata tagaataacg gtatcgccaa
     6781 tacaaaggtt aagatggcat gagagggagt tcctaagatg tccaatttta taaatactgg
     6841 gctgacacaa aatatcgtgc ttataagcag taaaattatt aaaattgtgt caaaaaaata
     6901 acgcttattt ttcatttagt ctactttcca ttgttaaata atactactgt taacaccaag
     6961 ccaacttagc acattgcatc acctaatcct acgctacttg tccataatcc tttaatgttt
     7021 ctactaaaat tattccaatc tcccccatca agatagctta tttatcctag acaacgccta
     7081 ctgcaacagt ataaataaga ttcatcagcc atcttttctg gcaatcatat gggtagacta
     7141 atgatatttc tagttactca aaaatatcta gctatactag agttatttct aatccctagg
     7201 acacttgtta atccaaatgt aacaaatttt caccccttaa taggactctt tctggaaaaa
     7261 atataaggtc tatctttata aaaaaatcta tcatattggg atggcatgca tctggaattt
     7321 aaacaagcta taaattcatt tataactact atttgtttag aggcaacagc atcttgtata
     7381 ccgccctcga aagaaccatc ttgtaattcc gaaatatttt tgtttaaata ttgttttgac
     7441 aaatctctta atgcttcatt atcgtaaatg attcccaaaa atccaacctt atatagtaaa
     7501 taatttaaac ttacaaagta attgaatccc atagtatatt tttctttata aagcaaaggt
     7561 aaaactttat aaaaaatatc taagtcaacc tcactctgat tctgaagcaa gtaggagtca
     7621 agcaaatttt caaaaatagc taacaatatg attggtgtaa agtttttgta ttcacatgtc
     7681 aagtattctg agtatcgtgc agatgatatt tcttttatat aactttttga aagcaagatt
     7741 ttttcaaatt catcatctat tattaatctt ctatttccaa tccaagcggt attaccaccc
     7801 aaataagatt gtacaaatag caatatataa gaaaacatga acgtaaatac tgaaaaaggt
     7861 agaattctat gcgtaaaaaa atagacgata atggtagcca ggagtaaaga tatctctcgt
     7921 gacaatcgaa ttcttttcag catctttttt aacagtccgt aaggttgtcc ttggcaatat
     7981 tcttgaacta aattaatcgg aatgacatct ctcaccattt ctggaaagta gagtaagttt
     8041 ataggttgaa atctccagct cccatcataa gtaaatggat atagaaccaa atacttaaaa
     8101 gatttttttc ttataaactt aattatcaca atatgaatga ctgttgcaat gaagtatatt
     8161 aaatataaaa gtaaaaccgc catcaatata cttacaaaaa tccccttgga atcaatcaat
     8221 ggaaaataaa atattgcaac tagaagcgaa taaagtcccg ctaataaata tttctgatca
     8281 tctttcattc aaaacaccat attatttact aagaatgcat caatacaata gagcaactct
     8341 gtaagtcaat atttgataaa gcaaagcttt aaacccttcc ccagacgtta gcttttattc
     8401 aacccactac agttgacaag gagcccaaat tattgataaa aactttagtc atcatcgtct
     8461 ctataaaaat attttctata cactcttgat aataccaaaa ttaatgccaa tatcatacca
     8521 agagctataa taatagaatt tattagattt attttagtat atccaatcac tagtccaata
     8581 attggactag cagacatgct tagatataat aaaaataaca aaaaatgaat ttcaccaatt
     8641 cctgcaaaaa aatgtttcat agctatagtt ttacgcccat aaatacccat caaatttacc
     8701 gtctacgata tctaaaccat atgcaatggc tcctcctaat gagaagactt cagcaacagt
     8761 agccgcaata ttaagagcat tagtaatagt tgccatacta actccaccaa tatatcttgt
     8821 tatagcactt agttacctag ataagatatc ctttagcttg cttccaaaat ttaagtctac
     8881 acctataata tgagttcata ttagtactgc taaatcctat ctatagtaat gtcaaacacc
     8941 taaataaagt catctctcca attcattcaa gaaatgaaga aaggcaaaaa atctttaaaa
     9001 taagaaaaat gcatattatc aggtgttcaa aaatattgat gatatacgtt atatagatag
     9061 aaagatttac tcaatctcat tttcaaattg agttttttcc cagcctcatt tttaatttat
     9121 atcttcaata gaatctaatg accgagctac tgtattacac agattaatat tatttagtct
     9181 gtaatttttt taaaaaactt aatagtaaat ttgctccact gattgctatc aatatttcaa
     9241 ttggtaaaaa atagtaattc caaataaaat gagaaatcag caatgataga aaaataacaa
     9301 tatcaatttt cctgttgttg acatactctg taattttatg atacagtaat gcaacaataa
     9361 ctgaaattaa aacaatcaac ataatactat tatcctatcc ttctcactaa ctctatttcc
     9421 aaaatttaat ttttggggga cttagtaatg aaattacaat taacaacaca cctaaaataa
     9481 ataaaaatat ctcccaaact ttattctcag ttttaataaa gctaccatat ctatctcatt
     9541 tcttattttt aaataattca tactcttttt ctctgataaa gggaactgaa aaattagaaa
     9601 aaattatcag aattgaaaac agatatacgt ctttttgtat cactaaaaca taacctaaaa
     9661 atatatagac catcaaatct agtacaaaaa gagaaaatat cctccttttc attaccttac
     9721 ttgccttaaa gattctgttt aatagaacct ttatcgtagt atctacacaa atttttatca
     9781 aaaagataag agccaataca cctgctgctg caccaataag ccaacctcca aggcctccaa
     9841 ccttaatata gtttattagt ttttttgtta aaactgcagc tccagtcaat gctataaaag
     9901 ttcctgggct catagctaaa gctgcgcaaa ttccttgaca agcactcttg cttaaataag
     9961 ccccccccat caagatacat catctcctct tgctcaagag caacataatt atttggtaat
    10021 acgagttcca tttattttct cctttatact atgtaatacc acaaaatgat tttgacctaa
    10081 atcattctta acttgaagaa tcgcaggaaa tgttaatttt ggagtcaaat cttccagtgc
    10141 cactcgaaca gcttttactg taaaattcaa cttattcaga cctgaaacaa taccactgac
    10201 agtcgttcca tacatgtctg taccaataat ttcccgaatc ttcatgattg atagttcctt
    10261 tttgtaagat aaaagaactg ttgaaacaac tgccgcagca caatctgact gatcatgttg
    10321 catcgtacaa ggatattttt ttaacataga aatactcaat tctttagaat taatctaact
    10381 tttctttgat gtcacccaaa cctcaatcac tgcccagtag ttcttgaatc agtttatttt
    10441 caatcgtatc attctttgtt cttgatatct ttccaagcat tgtagtacag cagatttttg
    10501 tccaaggact gagcctcctt taacaactca agctccctta cattatatcg accagcccca
    10561 tggaaagatt atgaccagac taatcaatga tatcatacat actagaatac aaaatatttt
    10621 tttattcata ctttttctcc tatctttatt ttctacctac atcatacctc ttattaagct
    10681 cattttaaaa ttacgttaac ttttttcaca aatttatttc gactttcttt tttacttttt
    10741 acattgctat gatacaatat ttttaacaag attttattat ttgttaactt ttttcacaga
    10801 aaggagaaaa tcatgcgtta tgatttcgga aaggtctata aagaaatacg tgagtcaaag
    10861 gggctgaccc aagaagaggt ctgtgggggt gttctctcaa gaaccagctt atcaaaaatc
    10921 gaaagtggca agacaacccc aaaatatgaa aatatggaat ttcttctccg tcaaatcaat
    10981 atgagttttg aagagtttga atatatctgt caactttatc aaccaagtca acgcacagag
    11041 attatgcaaa cctatctcaa tatgcgttcc attatcggga ccagcgatct tgtcaattta
    11101 tttcaaaaat gccaagacta cctcaagacc caccacgatc tccctataga agaaatcaga
    11161 gatatgcttg aagttgtcat ttatatccgt caacacgggg caggggaact atcagatcac
    11221 gcagaacagg ttgtcaaaaa actttggaga aaaattgaaa aacaagatac atggtatgag
    11281 agtgatctaa aaatcctcaa taccattctt ttcagttttc ccattgaata cctccatctc
    11341 atcactggaa aaatattgca acgcctagaa gtctataaaa actatcaaca tttatatgac
    11401 ttgcgaatag caatcctgct caacctttcc acactctatc tatacaatca agataaaaac
    11461 atgtgtaagc aaatctgcta cactttactg gaggacgcca agaataagaa aagctacgat
    11521 aggctggcta tctgctatgt ccgcattggg atttgtacag acgattctaa acttatccaa
    11581 aaaggtttct cactcctaga gctgaccgag gaaacttcta tgctgtctca tctcaaaaaa
    11641 gaagtagaga tctattacca agcgaaggaa agataaaaaa gccgagggag ctcctcgacc
    11701 ttttcataga atcgccgaac gatttaacga gaaagtatga cttttacgtt tatcccaact
    11761 caattatgac atttttttca aaagtcaata tatctcactt tttcaacgac aagaaagagg
    11821 ctgataatct accaacctct tattctgaac ccatcactcc atcacttttt agcttcattc
    11881 gctttcttag cgactgcaat ctggtattcg acttggtcat tccccttacc ggtacaacca
    11941 tgagcaattg tagtcgctcc tatctgatgc gctatttcaa ccaatttttt agaaatcaga
    12001 gggcggctca aggcagatac caagggatac ttttgttcat aataggcatg tgactgaaga
    12061 gccactagca cataatctgt agcaaattcg tccttaacat caatgacata agattctact
    12121 gccccaacct taagagcctt atcatggatg aaatctaagt ctttcccttc acccacatcc
    12181 atacaaactg aaacaacatc atagtctttc tttaaccagg taatagcaac tgatgtgtcc
    12241 aaaccgccag aataggccaa aattactttt tctttactca tgttcttttc cttctttcta
    12301 tttttcaatg gatgctttaa aggcatcctc aatgagtttg tctaattccc cagactcctt
    12361 caacttttga atggttttat cgactgcctc tttcaattcc ttgctatctt ttttcatggc
    12421 taccgcgtag gaatcatctt gctctttttc aaaattgagg tctgcgattg ctaaatcagg
    12481 attattttcc acaaatccct tggaaacagg ttcttcaaag ataacggcat ccacttgtcc
    12541 tgattttaaa tctgtgatta aattcccatt tttaggcaga gatacgaggg aagaattttg
    12601 tagcaaatct ttcgccatcg tctcttgaat cgaacctttc tgcgctccaa cctttttctg
    12661 cgccaagtcg tttacagact gataagtagt caagtcagat tttttgacaa tgagtttatt
    12721 ttttgcagta tagtagggaa tggaaaagtc aaacaccttg ctccgttcat ctgtcttaga
    12781 aacacctgat atggcaaggt cggcttttcc tgattgaaca ctagccagta cattatcaaa
    12841 actcatggga gatagttcca attcgacacc tagttctgtt gcgatagcct tggctaattc
    12901 gatatctgaa cccacaatct gatttttccc atcaaccact ttttggtatt caaatggagc
    12961 aaaatccgga ttgagggcta caaccaattt tcctttggac ttgatggctt caattccagc
    13021 cgattgattg ttgctacaag caaatagtag ggggagcatc actaaaccaa acatcgtcat
    13081 caacaccttc ttcatcttat tcataataaa gcctacttta tgtttattcc ttttgtttgt
    13141 ataaacaata catctatatt catcctttgt caagcctaaa ttgaaaaaat tttcaatttg
    13201 aaacaaaaaa aacctagaaa tactacataa aatgtcattc ctaggcgtat ttatgctatt
    13261 tttctctgga aaacatgagt attcagccag tcaaaaggag ctgaatgaac tcattttccc
    13321 tcgcccaatt caatgacacg atgacattgt tgggctacat aagcatcgtg ggtcacaata
    13381 atgactgttt tcccttctcg attcatctct aagagaaact tcaagaccaa atctctattt
    13441 tcaggatcca gcgaacctgt aggttcatcg gctaaaatca gctggctggg ttttaagatg
    13501 gctctagcaa ctgcaattcg ttgttgttcg ccaccagaca actcggagac cctttgatgc
    13561 aaagtagctg acaaacctac tctctctaaa atctcttcca cctttttgag cttgtctttc
    13621 ttaggcaatt tcacatattt cagcgccagc atgagattgt actcgaccgt ttcatcatca
    13681 atcagggcaa aattttgaaa cagataagag atatgttcac ggattattgt ttgcgactta
    13741 gcagaattaa ccgctagatt tgtctgacca aaaatctcat accgtccgct ataatcacca
    13801 tctatcaaac ccaataaatt taacaaggtc gacttcccac taccactctt accaacaata
    13861 gctaccaaat ccccctgatc aatcctgaga gataagttat ccaaaatcac ttttccccca
    13921 atggttttgg taatattttt caactcaatc ataagatgcc ccctttcaat aactctacta
    13981 gacttctttt ctccatccta gaagctaagc ctagcacaaa tagtatatcc agacatgtaa
    14041 aacctgcaaa cagtagaagt ggtaagaacg catgggcaaa gaaaatcaag actagaagag
    14101 ggaaactata gcccagcaag agcagaacga ggagaggacg gtagcgatcg accagtttcc
    14161 accccataaa cttcttggta atgatatccc tgcgcttcaa taagaaagtt gttactagta
    14221 agaagtagga aatcatcatg ctaaggagac caaacaaagc aaagagtagg ttaaaattcc
    14281 gaacagcatc tctataagaa tccactttct cttgttgaat ggcttgaata gatgaaaatt
    14341 ttaaataatt tccatctgac aatttctcaa ctaactctgt aatctctttt tgatgttgaa
    14401 ccgtattttc aattttaatc ggattattta agccagttgt tgacagggag gctttctcat
    14461 cccacatcat atcagaatca ttgaccaagc taataattgg attggagaga ttttcctttc
    14521 gcttatcact atatgggaaa aatgaccaat ctccttcata ataggcaatc tcgacatcca
    14581 tctcctctat cgttcgtttt tgctgctctt catacttcat cgaatgaaag gcaattaact
    14641 tccccaagag ctgattttta tcttcttcac ctttcgtact tgctggcatc aaaataactt
    14701 ttttaatacc ggtatctggt agcttgaatc ccttgctctt tagaaaattg cgattggcat
    14761 agtaaacatc caccgtatct gttaactgat attgctgaat ctgttctgat tggacaaaat
    14821 tttttacagg aagactgcta ctctgcacat agcccgcctg cgttttttct accaaatcct
    14881 gataaaatcg atagaaataa tctgtagatt tccctgaccc tgctagctct tcttgccaca
    14941 gattatcatt gagtttgaag gtttctaagg tcaggtaatt accttgactt acccactgtt
    15001 gctgataagc aagttctttg ttttcttgtt ctaaacttct gcccacccca atcagtaagg
    15061 ccgtcagtaa aatagttgtc cctattttca tcacataatt gaagataaga ccaaatttga
    15121 aagatgaaaa acctttcagc agagagctga ttgtcatttt ttggattaag aggtaagtca
    15181 accaactgat aaagagataa agctgcaaca gcaaaaaatg agacaaccac agcataggaa
    15241 acaaatcttt tggcttataa tcaagcaaga aaaacacgcc tagattgatc acaagagccc
    15301 cacctaggag gaggtaaagg ttgcctttta caacatcagc taaaacagcc ctatcttgaa
    15361 aaccaagtaa tttttgtacc ccaactcttt tcatctccat catcggttga tacactgtca
    15421 ctaacacaag aagcaaaata gccaagacaa aaacaatggc agataaaagc aaatctcgat
    15481 ttatgacttc cactgcactt ttgtaggtcg gctctagcaa ggtagcctgg tctatcttga
    15541 aaaaatcgct ccatttctgt acaatcctat ccttgtccat ctcttgtgta gaagttatcg
    15601 tatagcgacc atttaaacta cgagatgtat ccttgatata ggtttgaaaa gtcataagct
    15661 gaataggttt ggcttttaga aaggtcggaa tcgtaccaag tttattggaa atttctttat
    15721 tactatagac tccttcacca tctgtggtaa aatcaagaga agaaatccca aactcttggt
    15781 aggggaaggt atctttatca aaaacaccag acttgaccac ctcatcacca ctgtctgttt
    15841 tgatgatgga gactttatac tcctttgata catcctcaaa aaatcgaaga acagacgctg
    15901 caggttcgtt aatatctttc aaatacaaat ccaaagaatc tacagtcttt cccatttctt
    15961 gaatccgaac cacttctcgt gtatagttta cattaaaaac aaaaaaagtg gtacacagaa
    16021 gcaggagtaa catacagaaa ttactgattt ttttcataaa agtgcctcca ctacagtttt
    16081 ccctctccaa ataggagagg gaagaatttt actcaaatcc atagaaatat tccattcctg
    16141 ttggcggaat cttggtgagg gaagctctag cccatgcctc aggttttgca taatccttag
    16201 aggttctacc cccatgtcta acagttgctg tatgatatcg agtagaatgt aagtaatcag
    16261 aatatccaaa agttcctgtc caacctactc catagttcca ttgaccaccc tcaacccata
    16321 ctgctaaagc atttgtagta gcaagtatac cacataccat taaagatgca acactaattt
    16381 tctcatgatt tatttctcct attatcgaga gctgttccgt aaaaacagct atagtaattt
    16441 atcaacaagt atcgtagtcc attggactca ccttccttct atctcatttc atttttaaca
    16501 acgaacttac tcttaaccgg gagaatggtg cgcttctgta tcaggtcctt gaacaaccag
    16561 agtagtatta agcacactct aactattact caagaatcag tccaataaac aatatggata
    16621 gcgctttcaa atttttaaac tcctatccca tccttttatc tatataataa gtgaaaatat
    16681 aataactgtc aagtaactga agtgaatttt ataaaaaaat tacaagccaa atttgtaaag
    16741 tttacactaa gccgctaggg caatcgtcta tcagaatatc cgtttatttg tcaataatcc
    16801 gagaaaatct tgcaacgctt agaagtctat aaaaactatc aacatttata tgacttgcga
    16861 atagcaatcc tgctaaacct ttccacactc tatctataca atcaagataa aaacatgtgt
    16921 aagcaaatct gctacacttt actggaggac gccaagaata agaaaagcta cgataggctg
    16981 gctatctgct atgtccctat tgggatttgt agggatgatg cgaaacttat ccaaaaaggt
    17041 ttctcactcc tagagctaac cgaggaaact tctatgctgt ctcatctcaa aaaagaagta
    17101 gagatctatt accaagcgaa ggaaagataa aaaagccgag ggatttcctc gactctttac
    17161 atattatttg ttcgttagtt cttaatacca gccattgtta agccagaagt ttttagcagc
    17221 tgtccatgaa ccgtaacgtc ctgcaacgta ggcatctgct acacgttctt ggttttcagc
    17281 tgagtagtca ccgttcaggt atgaatctgt taattggtaa cgtccgatat aacgtccatt
    17341 tgtagctgta tagctaccac ctgattcttt ttgagcgatc cattctttgg cttctgcttc
    17401 agatccgctt acagttgaaa caactgtttc acttactact ggagtttctg ccactggagc
    17461 tgaaacagtt tcatcttgag cggctggtgc cgcataagta gctggcgctg gtgttgcaac
    17521 aggcgctaca gggccatcga taaccaactt ttgatcaaca taaatcaaat gaatgttatc
    17581 aatgtggttg ttttctgcca atttttcaac tgttgtgttg tgagtttcag cgatttctga
    17641 aagtgtatca ccttctttaa cagtgtaagt tgatgattct tgagcagata caaatgatgg
    17701 agcaaatact gcaaacaagg cagctactcc tgcaagagtt gctttaatct ttttagttat
    17761 tgatttcata ttcgaaaatt ctccttcttt ctatagttct atcataccct ttaaatatta
    17821 ccgtttcttg acacttttat gtagaaatat tacaaaatta ttttttattt ccctaaataa
    17881 ggtgtttttt gtcataaaag atactatttt tatgctattt gaggtattag aaaggttttc
    17941 atccacaatt aaagccaagc ccctcattct ttgatataat agagataaga atttttataa
    18001 ggggaaactg atgaaatcac ttcgttttca atctgtcttt gatatcatcg gaccagttat
    18061 gattggccca tctagtagcc ataccgctgg tgctgttcgt attgggaaga ttgtctcttc
    18121 catttttgat gatactccga cagaagttga attccaactt tttaactcat ttgccaagac
    18181 ctatcgtggt cacggaacag acctagccct tgttgcaggt attttaggaa tggatacaga
    18241 tgatcctgaa attccaaata gtctggaaat tgcccacaag cgtggtatca agattgtctg
    18301 gaccattcag aaagacagca atgcccctca ccctaacacc actaaaatta ctgttaaaaa
    18361 tgcccacaag accatcagcg tgactggtat ttctatcggt ggaggaaata ttcaggtaac
    18421 cgaactcaat ggttttgccg tctctctcaa tatgaataca ccgactatca tcatcgttca
    18481 tcaagatatt ccaggtatga ttgcccttgt tacagaggcg ctttcccgct atggtatcaa
    18541 tatcgcccag atgaatgtca ctcgtgaaaa agctggtgaa aaagccatta tgattatcga
    18601 agttgacagt cgcaactgtg atgaggctat cgaagaaatt cgaaaaatcc ctcatctcca
    18661 caatgtcaat ttctttaaat aggaggaagc atgttttatt ctatcaaaga attggtcgag
    18721 caagcagatc tggactttca aggaaatgtc gcagaactca tgattacaac agagtttgaa
    18781 ttgaccggtc gcgaacgtga agaagtcttc cttctcatgg aacgcaatct ggaagttatg
    18841 aaagcctctg tccaacttgg cctcaatgaa aataaatctc gtagtggcct gacaggtgga
    18901 gatgctgcca aattggatca ctacatcgaa aacggaaaaa ctctgtcaga ttatacgatt
    18961 ctctcggctg cccgaaatgc catcgcagtc aatgaacaca atgccaaaat gggcttggtc
    19021 tgtgccactc caaccgctgg aagtgctggc tgtctgccat ccgttctcac tgctgctatt
    19081 gaaaaattag acctcagcca cgagcaacaa ttggatttcc tctttgctgc tggtgccttt
    19141 ggactagtca tcgcaaacaa tgcctccatc tcaggtgctg agggtgggtg tcaagctgaa
    19201 gttggttcag cctctgctat gagtgctgcc gccttgactc tggctgcagg tggaacacct
    19261 tatcaggcca gtcaagctat tgcctttgtc attaaaaata tgctaggcct catctgtgac
    19321 cctgttgcag gtttggtcga agttccctgt gtcaaacgta atgccatggg agctagcttt
    19381 gctttcatcg cagcagacat ggccttggca ggtatcgaat ctaaaatccc tgtggatgaa
    19441 gtgatcgatg ccatgtacca agtaggagca agcatgccaa ctgcctttcg tgaaacagct
    19501 gaaggtggac tcgctaccac ccctactggt cgtcgcctcc aaaaagagat tttcggagaa
    19561 taagcttatc aaataggaga aaccatgacc tctatcacag cgattttttt cgatttggat
    19621 ggaaccctcg ttgatagttc tatcgggatt cacaatgcct ttacctatac ctttaaagag
    19681 ctgggggtgc ctagccctga tgccaaaact attcgtggtt ttatgggacc acctctcgaa
    19741 agtagttttg cgacctgcct gtccaaagac caaatttctg aagccatgca gatatatcgt
    19801 tcttactata aggcaaaagg catctatgaa gctcaactct ttcctcagat tatagacttg
    19861 cttgaggagt tatcgagcag ttatccactc tacatcacca cgacaaagaa tacatctact
    19921 gctcaagaca tggccaaaaa cttggaaatc catcatttct ttgatggtat ttatggttct
    19981 agccctgaag caccccataa ggcagatgtc attcaccaag ccttacagac acatcaacta
    20041 gcaccagaac aagccatcat catcggagat accaagtttg atatgctggg agctcgagaa
    20101 acaggtattc agaaattggc cgtcacttgg ggatttggag agcaagcaga tctactaaac
    20161 tatcaacctg attatatcgc tcacaaaccc ttagaagttt tggcgtattt tcaatagcat
    20221 agactgggta acaactccat ttcagaagaa aatgaagtaa tactcaatga aaatcaaaga
    20281 gcaaactagg aaactagctg cgggctgctc aaaacactgt tttaagattg tagatggaac
    20341 tgacgaagtc agctcaaaac actgttttaa ggttgtggat ggaactgacg aagtcagctc
    20401 aaaacactgt tttgaggttg cagatagaac tgacgaagtc agctcaaaac actgttttaa
    20461 ggttgtagat ggaactgacg aagtcagtaa ccatatacgg caaggcgacg ttgacgtgat
    20521 ttgaagagat tttcgaagag tataagtctc tacataataa aacgcatatt accaaggttg
    20581 tttaacttga taatatgcgt ttttcttttt tattcaatgt gggttgtttg attagcaaag
    20641 gcgataatag cttgcttcaa ctcatctcca ctgagagtgc ggaactctcc aatcttttga
    20701 ttgatggatt ctaaaggcat gacattaacc ttaccaacga aaatcttatc cataacttga
    20761 ttgtcaacga gttcggttga taccaagagt tcttcgtaga gtttttcacc tgggcggatt
    20821 ccaacttcaa cgattggaat ttcactctca gtgtggccac ttagaagcac catcttcttg
    20881 gccaagtcat aaatcttgac tggtttgccc atatcaagga taaagacttc cccatctttg
    20941 gcataagcac cagcatggat aaccagacga ctagcttctg gaatggtcat aaagtaacgg
    21001 gtcatgcgga agtctgtcac cgttacaggc ccaccttcag caatctgacg ttcaaagact
    21061 ggaatgacac taccacggct accaagaaca ttcccaaaac gaactgcaca gtaggttgat
    21121 tggctacgtt ggttaaagcc agtgacaatc aactccgcca cgcgcttggt tgctcccata
    21181 acatttggtg gattaactgc cttatctgtc gaaatcataa ccatcttagg caccttggct
    21241 tcatcaacgg ctctagcaac attgtaagtt ccacggatat tgtttttgaa ggcttctttt
    21301 ggattgcgct ccatcatagg aacatgcttg tgggctgccg catgataaac aatagcaggt
    21361 ttgtactgct caaagacttg caacaaacga tcatagtctt gaatgtccgc aatcacaggt
    21421 acataatcaa tcccttggaa cttacgaatc aattcatgat aaacaaggta gattgagttt
    21481 tccccatgac cgagcaagac aatgcgttca ggattgaagc gactaacttg acgacagatt
    21541 tcagaaccga ttgaacctcc agctcctgtg actaagatgg tcttacctgt cagttctgca
    21601 cccagacgcg attcgtcaag acggatttcc tgacgaccca aaaggtccgt aatatcaatt
    21661 ttttggaagc cagtacctgc ttggtgaagg ccctgaacaa cagtttcaac cttaggcatc
    21721 ttgtaacatt tgacacccag cttattacac atctgcaaga tacgctcata ttctgacgga
    21781 tccagcgacg gaatcgcaac gatgacacgc tcgatttgat ggcgtttggc taattcaggc
    21841 agattgtcat aagagcccaa aacaggaata ccaccaagtt tttgaccctt tttcttagaa
    21901 tccttatcca aaataccgac cagttctaat tcactggttg gatgttggta actatccata
    21961 aagagagccc caccatcacc ggcaccaatc aagaaggtcc gacggtgttc tccatcacca
    22021 ctaccttttt tgcgtctgga gtagattaac tgccaagtaa tccgtggcaa taaaatcaag
    22081 aaggtactca acaagataaa gagaatgatg aaacggatgg agaagagtgg caagaaggca
    22141 taacagatac tatatgacaa gacactgcta gcagtcacac caaaaaagat tttcatgaaa
    22201 tccgtaatct tgctgtaacg actaatgctc gcgttcaacc cccaaaaacc aatcatcaat
    22261 tgatagaaca agaaggccaa actcgtatag ataatgtagt caacaggtgc tggattaatc
    22321 agcccataaa ataaaatata agatacaatt atggaaacca ccatactgaa aatatcaaat
    22381 attccccaga aaacctgctt ttgttgttta tttaaaattt ccaccagatc aatcacataa
    22441 tctgttagtt ttttattcat agaaatctac tcctccttaa aagagtttta ctatattgtt
    22501 attatagcat attttgattt atttggctta ttttatccaa ataaattatt gttcccttgt
    22561 actccttctt ccatttaaat cctctaatta aacctacaat cgtcccaagg ccataagcaa
    22621 agtgaatgga aaataaaaga aagggcatca caattagaaa tccattttta tgttttaata
    22681 aagtcagcaa agtgagtaat gacaaaagta gaaaataggc acctaatagt aaagttatga
    22741 atacgaatgt gatcggtaac aatgctagac taaacacaag actcaaaaca aataaacaag
    22801 gaacatagtg aaataatgat aaacacttaa actgaacatg acttgtcaag ccaatccaca
    22861 aaccatttga atacttttga tgcagcattt tcttgaatgt tggtcgaata tactgataag
    22921 atagaatact tgggctatag cggattttat aaccatgttc tcgaattcta taatgaatat
    22981 cattatcttc agttcggcca agttgctcat ttactaaacc aaccttctgg aaaacctctc
    23041 gtttatacat cccatgaaaa atagaagaaa catatctatc ctcggaacta tttcgataat
    23101 tggcaatgct actgccaaac atattttcct caacaagatg caaggtctct gcccattttc
    23161 cttttccttc gacaatcgtc ggtctaggcc ccccacagac aaattcacct tgttgaataa
    23221 tagccacatt gttaattaca aaactctcag taacttttga atgagcatca atttttaaaa
    23281 taaggtcccc tacagaatgt ttaactccca ggttaaaacc actagcttga tttttcttag
    23341 gattgttata caatctaatt gagttaaact ctgtatcttc ctttataaat tgctgaatga
    23401 tagctgtggt cccatctgtg gacatagcat ttataaatag aatttcaata tcctctttag
    23461 gataggtttg attttttaag tcttcaatta gaccaggcag atatttttct tcattgtatg
    23521 cactgattac aatggatacg agaagacttt caacattttg agtcactact actctcctga
    23581 atttttcctt ccaccattct atcataattt tcaagacttt cccattttta tcttgaaagc
    23641 cagaaacctt acttgacatt atagtgaaaa agccttaaaa taagctgtta ttaaaatcag
    23701 ctagaagagg tattatatga aaaagcaatc actctttttt gttccaggta ttatcctgat
    23761 tggtgtttcc ttgcgaactc cttttactgt tttacccatt attttgggaa atatttcgca
    23821 aggtctggag gtagaagtta gttcgcttgg tgtcttgacc agcctgcctc tccttatgtt
    23881 taccctcttt tcaccatttt ctacccaact ggctcagaaa atcggcttgg agcatctctt
    23941 cacctacagc ctcttcttct tgaccatcgg ctcacttatt cgactaatca atctgcccct
    24001 gctctatcta ggaaccttga tggttggggc aagtgtcgca gtcatcaatg tcctgcttcc
    24061 tagtcttatc caagccaatc aaccaaagaa aattggtttt ctgaccacct tatatgtaac
    24121 gtctatgggg attgcaacgg ctctggcttc ctatctagct gtgcccatta cacaagccag
    24181 ttcttggaaa ggacttatcc ttctcctcac gttactctgt ctagcaactt ttttggtctg
    24241 gctcccaaat caccgctata atcatagact agctccacaa accaaacaaa aaagtcaaat
    24301 aaaggtcatg cgtaataaac aggtttgggc aattattatc ttttcaggtt ttcaatcctt
    24361 gatcttttac accgtcatga cctggttacc taccatgtct atccatgcag gtctatccag
    24421 tcacgaagct ggcttgctga cttctatctt atctctgatt agcattcctt tttcaatgac
    24481 catcccaagc ctgacaacca gtttatctac tcgcaaccgt cagctcatgc tcactctggt
    24541 ttcactagct ggtgtggtcg gcatttccat gctctttttc ccaatcaata atttcattta
    24601 ctggcttgcc atccatctcc tcatcggaac cgcaaccagt gccctcttcc cttatctcat
    24661 ggtcaacttt tcactcaaga caagcgcccc tgaaaagaca gcccaattgt ccggcctatc
    24721 tcaaacagga ggctatatcc tagcagcctt tgggccaacc ctctttggtt acagttttga
    24781 cctgttccac tcttgggtac catctgtagc tgccctcttg ctcatcgata tcctgatgac
    24841 tgtggccctc tttacagtgg acagagcgga taagatcctt taaacttcta gttttagcta
    24901 gaagtttttt atatataaaa attttacaca tttctcttga cagggctttc ttttagatgt
    24961 acaatgtatg tgtagaaaaa ttatatataa aaatcttaca cattagaaaa ggaggtttcc
    25021 catgtacttt ccaacatcct ctgccttgat tgaatttctc atcttggctg tactggagca
    25081 gggtgattct tatggttatg agattagcca aaccattaag ctgatcgcta atatcaaaga
    25141 atccacactc tatcccattc tcaaaaaatt ggaaggcaat agctttctga caacctattc
    25201 tagagagttc caaggtcgca tgcgcaaata ctactccttg acaaacggtg gtatagagca
    25261 tctcttgacc ctaaaagatg aatgggcact ctatacagac accatcaatg gcatcataga
    25321 agggagtatc cgccatgaca agaactgaat acctgactca gctagaactc tatctcaaga
    25381 aactacctga agctgaccgt atcgaagcca tggactattt cagagagctc tttgacgatg
    25441 ctggagtcga aggagaagaa gaactcatcg ctagtttggg aactcccaaa gaagcggccc
    25501 acgaagttct atccaatctt ctcgataaaa aaatcaatga agcacccgct caaaaaaata
    25561 accgacaaat tttacatatc gccttgttag ccctccttgc agcacctatc ggcattcctc
    25621 tgggaatcgc catcctcgtg accctgttcg caattcttgt agccgctttg actgtcattc
    25681 tggctttctt tgcagtttcc atactgggta tcatcggcgg attcctattt ttagttgaaa
    25741 gtttcactgt cctcgcccaa gccaaatcag cctttatctt gatttttggt tctggtttac
    25801 tggctatcgg tgcttcttcg ctagttttac ttggcatttc ctatgcaact cgcttcttcg
    25861 gtctactcat tgttcgtctg gtacaatttg ttcttaaaaa aggaaagaga ggtaatcagc
    25921 atgcgtaaat ggacaaaagg atttctcatc tttggtgtgg tgactaccgt tatcggcttt
    25981 atcctgcttt ttgtaggtat ccaatctgac gggattaaga gcctactttc catgtccaaa
    26041 gaacctgtct atgatagccg tacggaaaag ctaacctttg gcaaggaagt cgaaaaccta
    26101 gaaattactc tccaccaaca cacgctcacc atcacagact ctttcgatga tcaaatccac
    26161 atttcttacc atccatctct ttctgctcac catgatctta tcaccaatca gaacgataga
    26221 actctgagtc tcactgataa gaaactgtct gaaactccgt ttctctcttc tggaattggt
    26281 gggattcttc atatcgcaag tagctactct agtcgttttg aagaagttat tctccgacta
    26341 ccaaaaggga gaactctaaa agggatcaac atctcagcca atcgcggaca aaccaccatc
    26401 ataaatgcta gccttgaaaa tgcgaccctc aatacaaaca gctatatcct ccgaattgaa
    26461 ggaagtcgta tcaaaaacag taaactcaca acgcccaata tcgttaatat ctttgataca
    26521 gttcttacag atagtcagct agagtcaaca gagaatcact tccacgctga aaatatccaa
    26581 gtccatggca aggttgaact gactgccaaa gattatctca gaatcatcct agaccagaaa
    26641 gaaagccaac gaattaactg ggacatctca agcaactatg gttctatctt ccaattcaca
    26701 agagaaaagc ctgaatcaag aggtacggaa ttaagcaacc cttacaaaac tgaaaaaacc
    26761 gatgtcaagg atcaactcat tgcgagatct gatgataata ttgatctaat atccacacca
    26821 agcagacgtt gacaaaaacg cttacatttg ctactatgga aacatattta tctaactaaa
    26881 aaggaggttc taccatgaaa caagaatggt ttgaaagtaa tgattttgta aaaacaacaa
    26941 gcaagaacaa gcctgaagag caagctcaag aggttgcaga caaggctgaa gaaacgatag
    27001 ccaatctcga tacaccaatt ggaaaaaata ctcaagtaga ggaggaagtc tctcaagctg
    27061 aagtcgaact ggaaagccag caagaagaga aaattgaaac tcctgaaggc ggtgaagcga
    27121 gaacagaaat agaagaaaag aaggcatcta attctactga agaagagcca gacctttcta
    27181 aagaaacaga aaaagtcact atagctgaag agagccaaga agctcttcct cagcaaaaag
    27241 caaccacgaa agagccactt cttatcagta aatctttaaa aagtccttat atccccgacc
    27301 aagctccaaa atctagggat aaatggaaag agcaagtgct tgatttttgg tcttggctag
    27361 tagaagcgat caaatctcct acaagtaagt tggaaacaag tatcacacac agttacacag
    27421 cctttctctt gctcattctg ttttctgcat cttccttttt ctttagtatc tatcacatca
    27481 aacatgctta ctatggacat atagcaagca ttaacagtcg cttccctgag cagctagctc
    27541 ctttaactct tttttctatc atctctatcc tagtagcgac aacactcttc ttcttttcat
    27601 tcctcttggg tagtttcgtt gtgagacgat ttatccacca ggaaaaggac tggacgctag
    27661 acaaggttct ccaacaatat agtcaactct tggcaattcc aatcttcctc actgctattg
    27721 ctagtttctt tgctttcttt gatagcctac gatttacagc tctcttgtgt gtgattagca
    27781 ttggaatcat tctgcttgcc agtctccata tcattacaag accaagtcaa gcaagtgaaa
    27841 ccgactcctt ctatcaatta ttcttgtctg tccttgtgaa cggagttatt atcctcctct
    27901 tctttgtagc tgaagtggca ctgattggag attatcttcg tatcttggcc tttctttaaa
    27961 attcaatcct gtcatccttg gcaggatttt ttctatgtca aaaaagcaag tcgattgacc
    28021 tgcttctgct ttacttttct tgtgctaatg ttttaaaatc tttgtctaat atgggttgca
    28081 cttctatttg attggcgtct agttggtggt aaaaagatgg gggtaatacc tctaagaatt
    28141 ttgcatagtc caagcgagct atggattcat agtcttctgg tttagagccg tctcctgtga
    28201 tttgaaccaa gtcaatctcc cactggactt ccttatccac caattgctca atataggctg
    28261 caggaacaaa cggttctctc ggtaaaactg tcttgactcc ttgagctaaa tggtaaacgc
    28321 catgcacttt tccttctcca tcctgataga aggaaactct tgcaaagtag gcatctgtct
    28381 cttgaaccgc acgcacacgc gcttcaaact gagccaagcc atctgcctct aaaaagcttt
    28441 tcaagttctc acgactaaag aaaataggat taaaaattcc ttggcaaatc gtaaaacgag
    28501 ctacagggtc tgctagatag gcttgaatac ttgcttggaa ataagcttca aaatcaaaac
    28561 catctagccc ttcaatatca gtccctgtat aagcaagcaa agcatctaaa aatgacttga
    28621 taatctgcca gtctgtcttt gttagtaggt caggaagatc gacacggtaa gccttttgac
    28681 catcagcata actgacctta aagagaaatt gtgattgccc cactatcgca cactcaatat
    28741 actcgagacg attaagaggc tgacgaagat agactacatc atagctatgt gactccaaac
    28801 cgtctagcaa ggccaagatc gacttggcat tcaaaatctc ttgttctcct aaaatgctct
    28861 gtttatttgg aataaaaaat gtttttgcca taactggact cctttgaaat cgtttacata
    28921 cagtatacct tattttcctg aaagatacaa aaacaaactt tagatttttg agtacaaagc
    28981 atagaaaaac agcccctgag gactgtttga tcttatacag tagctgcctg atccaagctt
    29041 tcaccgatag cggctaggcg ctcaatcact tcagcttgtg tcaattcatt ttttgaaaca
    29101 tagcggttac gtgggtgaac acggcactcg tgtgagcatc cacgaaggta cttgtcttca
    29161 ttttcttctg atgtcaagat acgacggtta cagaagggat ttccacagtt gacataacgt
    29221 tcacatggtg ttccatcaaa ccagtctttc cctacgatgg ttgggttgac atggttgaca
    29281 tcaacggcaa tacgctcgtc aaagacgtac attttcccat cccaaagctc accttgaact
    29341 tctgggtctt taccgtaagt tgcgattcct ccgtgcaatt ggccgacatc tttgtagcct
    29401 tcacggacca tccagcctga gaatttctca cagcgaacgc cacctgtaca gtaaaccacg
    29461 acacgcttgt ccatgaattt ttccttgtta tcacggaccc attgtggtaa ctcacggaag
    29521 ttgcgaatat ctgggcgaat agccccacgg aaatgtccta ggtcgtactc ataatcgtta
    29581 cgtgtgtcaa ggacaacggt atctttatca agaagcgctt ctttgaactc ttttggagac
    29641 aagtaagcac ctgttgtttc aagtgggttg atgtcattgt caaagtcgtt gtcttccaaa
    29701 ccaaggtgga caatttcttt cttgtagcga acaaacatct tcttgaaggc ttgttcattt
    29761 tcttcgtcaa tcttgaacca gagttcttcc attcctggaa ggctgtgaac gtagtccatg
    29821 tatttttgag ttgtttcata gtcacctgaa actgttccgt taattccctc gtcagcgact
    29881 aggatacggc ctttaaggcc gattgattta cagaaagcca agtggtctgc agcaaattgc
    29941 tctgcatttt caattggagt ataaaggtag taaagtaaga cacgaatatc ttttgccata
    30001 agatttgttc tcttttctat tcttaaattt tctaaatttt ttatttatct acactagtat
    30061 acctgcttga gaaaacgaat gcaatttatt tgactggaaa ttgtagaggg ttctcgaaat
    30121 ttcctgaatg gttaaaataa ggacaagaga aaacatggat atctatatcc ttgtgccaaa
    30181 aaaaccactg ccctccccag accaacctga ggaaagcggt gattcttatt ttaggagtta
    30241 ggaatgaata cacgaaatca atttagctga ttattttttg tttttcaaga attcatcgta
    30301 ttgtttttgc atttcgttca atactttttc gtaggcacct tcagatttca atttttccat
    30361 caattctgga atcgctttat ctgggtctac agtaccagtg ttgatagctg tatcaaattg
    30421 ttgcattgtg ttagcaatag ctgagatttc agatttcaca ttgtcagtat tgaagataaa
    30481 tccaagcgct ggagattctt tagcttctgc caattctttc ttagaatttt cgatttgttg
    30541 gtctgtaacg ttttcgttga tgtaaaggat ccagttgtta ccagtgttcc atccacccat
    30601 gtgagtgttt cctttgtagc catcaagaac gcgaacacgg ttttctttac cttcaatttt
    30661 ttcccagttc ttgccttctg gaccgtaaac aagaccgttc aaaagttctg ggttcgtatt
    30721 caagaggttc aagatttcca ttgatttttc tttgttctta gagttgtttg agatgacaaa
    30781 gttagcaact tgtgttgttt ggtttttctt gatgaagtta gtgattggtt tgatttggat
    30841 atctttgttg gcaacacgtg aaagcaagct gttaccgtag tcagctggtc ctactgtttc
    30901 ttcacgaacg aaccaagtat cttgttgaag gtcaaatgaa gtgtcacttg ttgcgacgtc
    30961 ttttggaatg tagccagctt catagaattt gtgaagagtc ttcaagtgtt ctttgaaacg
    31021 aggcacttcg taacggttta caactttagt agtatcgcct tcaaggtcaa taacgaatgg
    31081 aagcccgttt gctactgggt agtcaaagtt atcagatggg atgaaaactt taccaatagc
    31141 aaatggtact acgtctggag ctttttcttt gatttgtttc aagactggct caagagtttc
    31201 gtaagaagta acacctgaaa tatcgatacc atatttggca aggagagttc cgttgaaggc
    31261 aaagttttga gatgatgcta cgttggctgc aactggtaca gcgtaaatct taccatttac
    31321 agtattaccc ttgatataag ctggatcaag tgccttgtaa aggtctttac cttctttttt
    31381 gtacaattct gtcaagtcag cataagcacc tttttgagca tttacaatat agttatctgc
    31441 aaaggcgata tcatagtttt caccagatga tgtgataact gacattttct taccatagtc
    31501 accccagcca aggtattgga tatccaattt ggcaccaact ttttcttcga tgattttgtt
    31561 ggcatttgct aacaattcat ccaagttatc tggtttgtca ccgatttggt acattttgat
    31621 aacaggtttg tcacctgaat cagcagcttt tttgctgtta cctgtcaaat ttccacaagc
    31681 agcaagacct gcagccaaag cgactacact agcagatgca aaagcatatt ttttccagtt
    31741 tttcatgata aaaactcctt tttttatttt taaacttata aacaatgtaa tgatcttaac
    31801 ttcacgcaag ggaagtttgg aaacaagtgc tattctttca caccaccgat agtcaaacct
    31861 tttacaaagt agcgttggaa gaatggatac aaaattgcga ttggaagggt tgctaccaca
    31921 accatggcca tacgacctgt ttctttcggt agagcaactc ccagttgacc agtcaagccg
    31981 accgctttgg caatgtagtc catattttgt tggatttgca tgagcaaata ttgcaatgga
    32041 tacaagttgt cactcttgat gtaaagaagg gcgttgaacc agtcattcca gaaaccaaga
    32101 gctgtcaaaa gcgtgatggt tgcgatacct ggtagtgaca atggcaaaca gatttggaag
    32161 aaaatccggg cctcactggc accatcgata cgagccgatt cgagaatggc ttctggaatg
    32221 gtcttcttga agaaggaacg catcaagatg atattgaatg gtgagagaag cattggaaca
    32281 atcaaggccc aaacagtgtc accaagctga agtacacggg tcaccatgat ataacctggt
    32341 accaaaccag cgttgaacaa catactgaga aggacgaaga tggtaaaaaa tctgcgatac
    32401 ttaaaggttg tccgtgaaat agcgtaggca taggttgttg tgataaagac atttgtcaat
    32461 gtcccaacta cggttacaaa gacagagatg aagagggctt gtaggatttt atccttaaac
    32521 tgtgccaaaa actcaaaacc gtctaagcca aattgggatg ggaagaagct atagccgtat
    32581 tggaggaggc ttttctcgtc tgtcactgaa ataatgataa cgaatacaaa aggtaggata
    32641 caagagaggg caatcaaacc cgaaatgata ctgaagaaga tatctgcttt cttactgaag
    32701 gagtgaatgc cgacattatc aattttttct tttttaattt tcttttttgc catattctcc
    32761 tcctttctag aacaaagctg agtttggatc gactcgtctt gcaagcaagt ttgataggat
    32821 aaccagaatc aaaccaacaa cggattggta aagaccggct gctgcagcca taccgatatc
    32881 tgctgtctga gtcaaaccat taaaaacata tacgtccaaa acgttggtta cattgtaaag
    32941 ctgaccagca ttgtgtggga tttgatagaa gagaccgaag tctgcgcgga agatatttcc
    33001 gactgcaagg atggtcaata cagttacaag cggagtcaac tgaggaatgg ttacgttgcg
    33061 aatacgttgc cacttgctag ctccgtccac tgtcgctgct tcgtagtagg ttggatcaat
    33121 tcccatgatc gtcgcatagt acatgacact gctatatcca aaacctttcc aaatacctag
    33181 gaaaagtagg agatagggcc agatgcccag gtcagcgtag aaattgactt ctttgagacc
    33241 aagactttcc aatagatgat tgaacacccc tttatcaata tttaggaagg catctgtaaa
    33301 gaaactgatg ataacccaag acaagaagta agggaacaac atagaagttt ggaaaatctt
    33361 caccattctc ttagaacgga gctcgctgag gataatggca atccctacag atacaactaa
    33421 acctagaaag ataaagccaa gattgtagag gacagtattt cgtgtgataa taaaggcgtc
    33481 tcttgaacta aataagaatc tgaaattatc gagtccgacc catttactat ttatgatact
    33541 atctatgaaa ccattactgg tcatgtggta gtctttgaag gcaaccacgt tcccaaatac
    33601 tggaatgtaa aagaatagaa tcaaccagag tgcccctggc aaaaccatca agagaaagat
    33661 ccagttgtct ctcaatgttt ttgaaaactt tttcataatt tcctcccttt ttattttgat
    33721 atccatctaa aaattctttt ttagactttt gataacgatt acattattag tatactccta
    33781 tttgcaggtt aggttaaact cctaattata gaaaaaattc cacaaattat gtagcagatt
    33841 taaaacttta tcaccactat caaacaaatg tcctaaatca attgtttatt ttatctctat
    33901 tagcccagtg atggcgtcac tctgttataa gcatccaaca acggggtata ctgaaaaatc
    33961 tccagactag ggaactcagc gatagttcct aatctggaga tttttaatat gttattaggc
    34021 gtttgctttc aacttagcaa taacctcttt aagattatca atcaactctg cttcagtatg
    34081 ctcagagcct ttttcatctg ccaagaacaa aactgctttt tgaagttctt cttgagagtt
    34141 ttcaaggaca tccttatctg ctgtttcttt gcccgctgtt tgtcctccat ccttagttgc
    34201 tgactggctt tccttaatgg actctaggga agcaatggca tctttgactg tttgcaagat
    34261 atcacgtaaa ccttgctctg tcaaactatc atctgtaaga gctttcttag cctctgccaa
    34321 aaccagacgt gctgaatctg tggtaggatt cgatacacct gtcaatgatc tcaaaagatt
    34381 ttctaaggtt tgagtctgct tactaatact agactaaaat caaaaagcat tacataacag
    34441 tgatatgaaa tcaactaaag aagaaatcca aaccatcaaa acacttttaa aagactctcg
    34501 tacagctaaa tatcataaac gccttcaaat
//
LOCUS       DBEJKC010000019        34005 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.019, whole genome shotgun sequence.
ACCESSION   DBEJKC010000019 DBEJKC010000000
VERSION     DBEJKC010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34005
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.019"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(99..1026)
                     /locus_tag="ACL3G6_000912"
                     /pseudo
     CDS             complement(99..1026)
                     /locus_tag="ACL3G6_000912"
                     /inference="COORDINATES: protein motif:HMM:NF015038.4"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            1008..1315
                     /locus_tag="ACL3G6_000913"
                     /pseudo
     CDS             1008..1315
                     /locus_tag="ACL3G6_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1338..1688)
                     /gene="tnpB"
                     /locus_tag="ACL3G6_000914"
     CDS             complement(1338..1688)
                     /gene="tnpB"
                     /locus_tag="ACL3G6_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR0545469.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPKINLSESRDFY"
     gene            complement(1669..1854)
                     /locus_tag="ACL3G6_000915"
     CDS             complement(1669..1854)
                     /locus_tag="ACL3G6_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545470.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(2158..3720)
                     /gene="guaA"
                     /locus_tag="ACL3G6_000916"
     CDS             complement(2158..3720)
                     /gene="guaA"
                     /locus_tag="ACL3G6_000916"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HGR0545471.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3862..4560
                     /locus_tag="ACL3G6_000917"
     CDS             3862..4560
                     /locus_tag="ACL3G6_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0545472.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQISYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4603..5499)
                     /locus_tag="ACL3G6_000918"
     CDS             complement(4603..5499)
                     /locus_tag="ACL3G6_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR0545473.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILHIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5508..6443)
                     /locus_tag="ACL3G6_000919"
     CDS             complement(5508..6443)
                     /locus_tag="ACL3G6_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGR0545474.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSAPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARFLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6440..7165)
                     /locus_tag="ACL3G6_000920"
     CDS             complement(6440..7165)
                     /locus_tag="ACL3G6_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HGR0545475.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(7249..7884)
                     /locus_tag="ACL3G6_000921"
     CDS             complement(7249..7884)
                     /locus_tag="ACL3G6_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGR0545476.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEKYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(7886..8713)
                     /locus_tag="ACL3G6_000922"
     CDS             complement(7886..8713)
                     /locus_tag="ACL3G6_000922"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0545477.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8735..9070)
                     /locus_tag="ACL3G6_000923"
     CDS             complement(8735..9070)
                     /locus_tag="ACL3G6_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HGR0545478.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(9071..9661)
                     /locus_tag="ACL3G6_000924"
     CDS             complement(9071..9661)
                     /locus_tag="ACL3G6_000924"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF021127.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HGR0545479.1"
                     /translation="MGDFEGTINKDHYLAGYLLFNAPAEVMDAIKEAGYHVLDLAHNH
                     ILDSQIEGVISTADIIEKAGITPIGVYTHEPRDQAPLVIKEVNGIKVALLAYSYGFNG
                     IEQYISQEDYNRYLSDLNEDKMKVEIERAEKEADITIIMLQMGVEYRLELTEEQKALY
                     HKMIDWGADIIFGGHPHVVEPSETVEKDGDKKLIIY"
     gene            complement(9677..9799)
                     /locus_tag="ACL3G6_000925"
     CDS             complement(9677..9799)
                     /locus_tag="ACL3G6_000925"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545480.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQGD"
     gene            10312..10923
                     /gene="def"
                     /locus_tag="ACL3G6_000926"
     CDS             10312..10923
                     /gene="def"
                     /locus_tag="ACL3G6_000926"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGR0545481.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            10968..11696
                     /gene="rlmB"
                     /locus_tag="ACL3G6_000927"
     CDS             10968..11696
                     /gene="rlmB"
                     /locus_tag="ACL3G6_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HGR0545482.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(11735..12646)
                     /gene="trxB"
                     /locus_tag="ACL3G6_000928"
     CDS             complement(11735..12646)
                     /gene="trxB"
                     /locus_tag="ACL3G6_000928"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HGR0545483.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(12712..12936)
                     /locus_tag="ACL3G6_000929"
     CDS             complement(12712..12936)
                     /locus_tag="ACL3G6_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HGR0545484.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAGARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13014..13757)
                     /locus_tag="ACL3G6_000930"
     CDS             complement(13014..13757)
                     /locus_tag="ACL3G6_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0545485.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(13757..14557)
                     /locus_tag="ACL3G6_000931"
     CDS             complement(13757..14557)
                     /locus_tag="ACL3G6_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0545486.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(14715..15071)
                     /locus_tag="ACL3G6_000932"
     CDS             complement(14715..15071)
                     /locus_tag="ACL3G6_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGR0545487.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLSVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15084..15596)
                     /locus_tag="ACL3G6_000933"
     CDS             complement(15084..15596)
                     /locus_tag="ACL3G6_000933"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HGR0545488.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15596..16090)
                     /locus_tag="ACL3G6_000934"
     CDS             complement(15596..16090)
                     /locus_tag="ACL3G6_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGR0545489.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16225..16671
                     /locus_tag="ACL3G6_000935"
     CDS             16225..16671
                     /locus_tag="ACL3G6_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HGR0545490.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMINNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16668..17315
                     /locus_tag="ACL3G6_000936"
     CDS             16668..17315
                     /locus_tag="ACL3G6_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HGR0545491.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKNVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASVLQYIAIVYYM"
     gene            complement(17336..17917)
                     /gene="pdxT"
                     /locus_tag="ACL3G6_000937"
     CDS             complement(17336..17917)
                     /gene="pdxT"
                     /locus_tag="ACL3G6_000937"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HGR0545492.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLLIREAILSGLPVFGTCAGLILLAKEITSQKESYLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(17918..18793)
                     /gene="pdxS"
                     /locus_tag="ACL3G6_000938"
     CDS             complement(17918..18793)
                     /gene="pdxS"
                     /locus_tag="ACL3G6_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042819 - vitamin B6 biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HGR0545493.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(18945..20324)
                     /gene="nox"
                     /locus_tag="ACL3G6_000939"
     CDS             complement(18945..20324)
                     /gene="nox"
                     /locus_tag="ACL3G6_000939"
                     /EC_number="1.6.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="H2O-forming NADH oxidase"
                     /protein_id="HGR0545494.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20618..21541
                     /locus_tag="ACL3G6_000940"
     CDS             20618..21541
                     /locus_tag="ACL3G6_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HGR0545495.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     IFWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21601..22206
                     /locus_tag="ACL3G6_000941"
     CDS             21601..22206
                     /locus_tag="ACL3G6_000941"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGR0545496.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22225..23469
                     /locus_tag="ACL3G6_000942"
     CDS             22225..23469
                     /locus_tag="ACL3G6_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGR0545497.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGCHGGDADATAGASY"
     gene            complement(23585..23842)
                     /locus_tag="ACL3G6_000943"
     CDS             complement(23585..23842)
                     /locus_tag="ACL3G6_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HGR0545498.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(23884..25920)
                     /gene="glyS"
                     /locus_tag="ACL3G6_000944"
     CDS             complement(23884..25920)
                     /gene="glyS"
                     /locus_tag="ACL3G6_000944"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HGR0545499.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKEIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGGRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKKIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26132..27049)
                     /gene="glyQ"
                     /locus_tag="ACL3G6_000945"
     CDS             complement(26132..27049)
                     /gene="glyQ"
                     /locus_tag="ACL3G6_000945"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HGR0545500.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(27417..28178)
                     /locus_tag="ACL3G6_000946"
     CDS             complement(27417..28178)
                     /locus_tag="ACL3G6_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGR0545501.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFFTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKIFPLLDWFVQQKLIEKEI"
     gene            complement(28451..29293)
                     /locus_tag="ACL3G6_000947"
     CDS             complement(28451..29293)
                     /locus_tag="ACL3G6_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGR0545502.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYHAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(29407..30798)
                     /gene="pgdA"
                     /locus_tag="ACL3G6_000948"
     CDS             complement(29407..30798)
                     /gene="pgdA"
                     /locus_tag="ACL3G6_000948"
                     /EC_number="3.5.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050119 - N-acetylglucosamine deacetylase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-N-acetylglucosamine deacetylase
                     PgdA"
                     /protein_id="HGR0545503.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKSFSDQDLSAWNFDYKDS
                     QIILYSSPVLENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(31036..31404)
                     /locus_tag="ACL3G6_000949"
                     /pseudo
     CDS             complement(31036..31404)
                     /locus_tag="ACL3G6_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            31643..32620
                     /locus_tag="ACL3G6_000950"
     CDS             31643..32620
                     /locus_tag="ACL3G6_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGR0545504.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYSKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGTLFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQDPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            32617..33699
                     /locus_tag="ACL3G6_000951"
     CDS             32617..33699
                     /locus_tag="ACL3G6_000951"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0545505.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTLIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGSEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(33763..>34005)
                     /locus_tag="ACL3G6_000952"
     CDS             complement(33763..>34005)
                     /locus_tag="ACL3G6_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0545506.1"
                     /translation="DNAIWHKSSTLKIPTNIGFAFIPPYTPEMNPIEQVWKEIRKRGF
                     KNKAFRTLEDVIQGLEKEVIKSIVNRKWTRMLFESR"
BASE COUNT        10071 a         7623 c         6137 g        10174 t
ORIGIN      
        1 atagctcttg ctttagctcc ttcaaaactt tgagaaaaaa ccaccctcgc ttttttaaac
       61 tgagcttagg ctaaaagagt ccagtggact cttttactcc gtcccataac caatgattta
      121 atggcgcgtt cagctagatt attggaaagg accagatgtc cgtcttttaa aatggtctta
      181 aaggtttctt catacttgag gctgtattca attgcccttc ctggttttga acctgctaaa
      241 actgactgac ggcggcacca agcaaagaag tcttccatta agggctggac gtttctgtag
      301 tcgttcatca gctggcaaag cctcccagtc tctttccaag gcaaataact ggtcacgata
      361 ggctaaacct ttagctccta aggatgattt atctgcttgc ttgggggtcg cttcaaaaaa
      421 tttccttctc acatgcgccc aacatccaac aagttcagct tcttccagtt gacgataagc
      481 ttctagcggt tcgcagttta ccaagcttag cgtcgccttg ctcctaaacc ttagactgct
      541 atcgcatagg cagaactaga ggactaaagt tctaagttac tgccgcaaca tatcacaatg
      601 catatagcca gaataatttc ctaggaattc ttgcactacc gaaccactcc gacgctgatc
      661 atggtggtac agcgtaatcc cttgtttctc agctttccca gacaaaaaag tccaatagta
      721 agtcagctga ctatcacttt ctaagacccg ataagaggtt tcatctgcat gaagaagagc
      781 ttgttctaac aacttttctc gtaaaaggtt ataaaggggc tccaaatagt attgactcgt
      841 cttgatatgc caattagaga tttccttacg tgtgattggt aaacccatcc tagcccaatc
      901 ttcttcttgg cgataattgg gtaccttcag attaaacttc tgatggatgg tgtgagcgat
      961 aatagaagct gagccaaggc tatgcgccaa aggggcttta ggaataggag ctttcacaag
     1021 cttatccaga tgattatctt ttactcgtta tggacaatgc tatatggcat aaatcaagta
     1081 ccttaaagat tccgactaat attggctttg catttattcc tccatacaca ccagagatga
     1141 acccattgaa caagtgtgga aagagattcg taaacgtgga tttaagaata aagcctttca
     1201 aactttggaa gatgtcatga atcaacttca agatgttata caaggactgg agaaggaggt
     1261 gataaagtcc atcgttaatc ggagatggac tagaatgctt tttgaaagca gatgagtata
     1321 aaaagaaagt cctcatttca atagaaatca cgactttctg ataaatttat tttgggagtg
     1381 atagaaaagc ccttcataag ccaatctact tgttcaggtg tgagagcttt gacatccttt
     1441 tctgtactgg gccaagtcag tctgccgttc tcaaagcgtt tatatagtag ccaaaatcct
     1501 tgaccatccc agtaaagggc tttaaagcgg tctttacgtc caccacaaaa gagaaaaact
     1561 tgaccggaga aaggatccaa ttcaaagtgg gttttaacca gataagccag tgaatcgatt
     1621 ccttgtctca tatcagtctt cccacacacg agatagacct gccctaggct agatagatga
     1681 attgtcatag agcaacacct tatccaaaag ctgttctacc atttcgagat tgagagattg
     1741 aaaaaaactt acttcaagct tgccaatacg aattttaagc agaatatcat ttctcttttt
     1801 agaatcaaaa ggacgagatt gtggaatctc tacaggaaca ataggttgtg gcattaaaat
     1861 atcctccaat agttttactt tactaatagt atacaggagg aactccatga atgatagata
     1921 ccttgttatg acgcgcttac tatattagaa agttggctct ctaattaaat taattctcat
     1981 tatatatatc aaaagaccgc agtttgaaaa ctacggtcta attttttgtc caaatgtaaa
     2041 tcacttggaa ctattattca atttattctt tttagtaaat gttcccgttt taatcccagt
     2101 tacagttttt aatcctctgt aaccgttgat tttacaaagc ttttaatttt tttgcgatta
     2161 ctcccactca actgttgcag gtggtttact tgtaatatcg tagacgatac ggttaacatg
     2221 atccacttca tttacgatac gtactgagat tttttgaagt acttcccatg gaattttggc
     2281 aaaatcagca gtcataccat cgatagaagt gatagcacgg attgcaatcg tgtagtcata
     2341 cgtacgaccg tcacccataa caccgactga acgaacgcct gtgttaacag tgaagtattg
     2401 ccaaatatcg cggtcaagtc cagctttagc gatttcttca cgaagaatag cgtctgattc
     2461 acgaacggtt tcaagtttct cttcagtgat ttcacccatg acacggatag caagtcctgg
     2521 tcctgggaat ggttggcgcc atacgatatg gtctggcata ccaagctctg taccaagagc
     2581 acgaacttca tccttgtaaa gagtattgag tggttcaatc aattcaaact gcatatcttc
     2641 tggaagacca cccacgttgt ggtgtgactt gatagtttga gctgtatccg taccagactc
     2701 gataacatct gtatataaag taccttgagc aaggaatttc acatctttga gcttgcttgc
     2761 ttcgtcatcg aatacataga caaactcgtt accaatgatt ttacgttttt gttcaggatc
     2821 agaaacgcca gcaagtttgt caaggaaacg tttagcagcg tctgctttga cgatattcaa
     2881 accaaactta ccaccgagca tgtccataac ttgatcagct tcgcctttac gaagaagacc
     2941 gtggtctacg aagatacaga tcaattgatc gccaatcgct ttttggagaa gaaccccaac
     3001 gacagatgag tcaacaccac ctgatagacc aagaaggaca cgtttatcac cgacggtttc
     3061 acgaattttt ttgatctgca tgtcaatgaa attatccatt gaccagtcac ctttagcctt
     3121 acaaatgtta agggcaaagt tacgaaggat atcatttccg tatacagaat gacgaacttc
     3181 tgggtggaat tggataccgt aaatgtgttt atctgggttt tcgatggctg cgtatgggca
     3241 gtcagctgat gtacctgtac gaacaaagtc agcaggaatc tcagtaaccg catcaccatg
     3301 gctcatcaaa acagtctgtt catcaggtgt tgattcaaaa agcgctgatg gtgtgtgagt
     3361 tagggttgat tgaccgtatt cacgatttcc agcatcacct gcaggaacaa cttttcctcc
     3421 aagtttatgg gtcaataact gcataccata acagattccc aaaattggaa ttccgagttc
     3481 gaagatttct gggtcaatat caaatgaacc atcttcatat acagaatttg gaccacctga
     3541 tagaataatt cctacaggat tgacttcacg aacttcagca gctgaaattt tatggctttt
     3601 tagttctgaa aaaacaccaa tctcacggat acggcgtgaa atcagctggt tgtactggct
     3661 accatagtcc aatacgatga ttttttctac atcttgcaaa tcagttgaaa tgttgctcat
     3721 ctttttcctt tctcaaaaga aatatctttt ctcaatattc tatcacaaat aagggcgaat
     3781 taccaactaa acaaggcgaa gtttgacttt ttctagttta ttggggtaca atagagaaaa
     3841 gatagaaatg aagtgaaaaa tatgctacct gcttatatga aaatccatga tcagataaaa
     3901 aaggatattg acgagcaccg ttgggctatt ggtgagaggc ttcccagtga aagagattta
     3961 gctgagcagt ttgcggtcag tcgcatgacc ctccgccaag ccgtatctct attagtcgaa
     4021 gaaggcgtct tagagcgccg tgtaggaagc ggcacctttg tttccagtac tcgagtacaa
     4081 gaaaagatgc gagggacaac cagttttact gaaattgtca aatcccaagg taaagttccc
     4141 tctagccagc tcatttccta caaaaaaacc attcccaatg agcaagaagt tgccaagcta
     4201 ggaatttttc caacggacaa tattatccga atggagcggg tccgctatgc cgaccaagtt
     4261 cccctagttt atgaagttgc ttctattcct gaaaaattca ttaaggactt taaaaaagaa
     4321 gaaatcacca gtcatttctt ccaaaccttg caaaaacatg gctatcgtat cggtaaatcc
     4381 caacagacca tctatgctcg ccttgctaaa gaaaagattg cccactattt ggaagttgaa
     4441 aaaggacatg ctattcttgg attgacccag atttcctacc tagaagatgg tactgctttt
     4501 gaatacgtaa aaagtcaata tgtaggcgaa cgctttgaat tttatcttga aaataattag
     4561 attaccacgc aaaaactctc tgtcacggac aaagagtctt ttttattttt ctaagaataa
     4621 atctttcaaa gaaatcaaag ttacagcaaa caatatcatt gccataccaa gaaaatcaat
     4681 gggataaaat tgttcattca ttattaagaa ggcaaagaaa atcgccgata ttggctcaat
     4741 tgaagccaac aagcttgact tgaccggtcc tatcagactg gctcctttaa ggaaagctgt
     4801 ataggcaaag acagtcccga taaggataat gcctgcaaac gcaaggagaa aatcaagact
     4861 agtcgggata tcggcctgta gaacccctgt aaaaggaagg gcgaccaaac ctgctatgac
     4921 cattcccaca ccaatgacca agctgctccc ccacttttta atcaaggcta tgtgtaaaat
     4981 gatatacaaa gcataagtca aggcagaaaa gagaccccag aacagaccag caggtgtcat
     5041 ggataactgg tccaactgcc catgtgttgc gatcaggaag gttcctccga tggcgaatat
     5101 gatggaaact atctctccca gtgtcggtgc caccctatcc ttgatacagc tataaattaa
     5161 aattccgaca ggacaaacat actgaagcac cgtcgctgtt cccgcattgg tctcctgaat
     5221 agcagacaga taggcgaatt ggttgagaaa aagaccaatc agagcaaaaa taagaagaga
     5281 cagcaaactc tttctatcct ttaaaaagac cagtatttta tcctttgcag tagcataagc
     5341 caagagcatg agaattccac cagcgattaa aagacgcaag ttagtcaaga ccagagccga
     5401 aattccgtgt gccattaggt attggccact cgttcctgac aacccccaag caataccagc
     5461 cacaactgtt agtaaagtcc cttttaaact atttgacatg tctctcctta ctcttctttg
     5521 cgaatcaagt tcatcacttg attgcggtct aatatccatt gagctctctc gtccttttca
     5581 taggtacgat tcgataggaa aatagtggct tcttgcttct gacgattcca catgataaag
     5641 gtacctgtat agcccgtatg gtctagccaa tctccttcca aattccatgc taaagaacgt
     5701 tccttgtcat ccaaaggaga aaaattttga tttaagtctc ttgcaaaatc atctgctaaa
     5761 tagtgttcta aaaagatttg taaatccttt atagtcgaaa ataaaccagc actcccagca
     5821 tgtctaccca ggaaacgagc cttgggatca tgcactatgc ctgcctctac acctctaact
     5881 gttggaacag caagctcaac tggcccaaac ttagtttccg tcattcccca aggtttccag
     5941 acttgatcct ttaaaatcac atccaaatct tgattaaaaa ttctttccaa aataaagccc
     6001 aacagcaaaa aatggacatc cgaataaaga aaggctggct gacttcgtct gttgagatga
     6061 aacatcgctt cctttaattc aggggctgtt aaaagatcac gattaggaat aaaaggatca
     6121 aggtctgttg catgagtcaa gagctggcga atagtgatgt ctggataatc actctcaggt
     6181 aaaaaatcta ttaccagtct atcaatatct aattgaccta tttcccacaa gaaggtacaa
     6241 actgtgccaa ccccaacaac cttgctgaca ctagctaggt cataaactag tcctgcctca
     6301 gtctgcaagc catgctctgg ggcactctgg cctaaataga actctgtcca ttgattgtcc
     6361 ttaaaatacg caaaagaggc tccgggataa attcctgcct cgatttgttc ttctattttt
     6421 ttaataatct tggtccactt catacttctt caaaccacaa ttcaacatta tttctatctt
     6481 taccaaggaa gaatttttca gacttaggaa taaaatattc agtagactca aacttctggc
     6541 gaagacttgc tatgtctaat tcattgacca agaacttgag catagataag tcccaggtaa
     6601 ccgtattgtc cacagtcaaa tcctgcccct gagctggaat aaaatcaagg gatgccccaa
     6661 tttcagatga ttccaagaaa ctttcgatat cagttgggag atgtaattcc atagaaatct
     6721 caaatttact taaagaaatt gatgccaaat ctgtttgaaa ttcaggcttt tctcctactt
     6781 ctactagact tgctctgtca tcttccgcat gaatcaaaat caaatcatct tctggtgaga
     6841 aaatttcaaa agcgtagcca ttttgacctt tatataatcg atgaatcgaa tctgttttag
     6901 ataagattcc ttcaatttct aagggatttt ccaccttgac aatcaatcta gctagttttt
     6961 ttcttccctc taccttacga gtacgcatac tgggagcttc ttctaaaacc agcttttcaa
     7021 gacccgtttg gtcacctagt gacagaaagg ccgattcttc taacagggcc ttcattccaa
     7081 gggtttcaat ataaaatgtt tcatttaatt ttctattatt agcttttaaa gtaggaataa
     7141 tccgtacaat ctgatttaca ttcataaatt cctccgtcac tttttatttt aaaggatttt
     7201 agaatttttt acaagatatt atgctcaaat ttaacattat ttagctattt agtaaagata
     7261 gtctttcaag gcttttgaca aagcctgata accagcaata ctgaggtgca gtccatcagt
     7321 tgtatattct tttttgagtt ggcctgcttg gtctgtcaaa caatcaaata ctggcacaaa
     7381 ttccacctgc atataggcag atgcaagctc ttgataggct tgattccaat tctgaatttt
     7441 ttcattcgag cggatataga ctgcctgctg gtacttctct ccctcattga caggcaaaat
     7501 ggaaagcaat ttaatctctg tcaatggata atcgcgagca acggattgaa tgatagcttc
     7561 gagattattg agagcctcat tcacaggaac atcctttccg atatcatttg tcccaatcag
     7621 aagaaaaatt ttatctactg ctccaccata tagatgagca tcaaggttct ctagtaacag
     7681 tcctgtctga tagccacgaa ttcctcgatt gacaatcgtc tttgaagtcc caaatagctc
     7741 ctgtagagga taatactcga caatggaatc cccaataaaa agaatgtttg gttctacaac
     7801 agaaatgtga tttaggtgac gatatttggt ttgaattttt tcttgttcct ttaggagcca
     7861 attttctaat aactgtactg ccacttcatt ctcctttttc taaccagttt tccaagactt
     7921 gataaactcc tccttggctg ttggctggtg ctagagcagt cgccacagct ttggctttct
     7981 catcagcatt ttccatcgca taggcaattc cagccatttc aagcatttca acatcatttt
     8041 cactatcacc aaaagccatg atttcttggg atttcaagtc ccagcgcttg agtaattcct
     8101 ccaagcccca tgctttatga atcccagctt ggaggatatc aatgcaacca tagccactgg
     8161 atacagctcg gacacggcca tcaaagagag cattgatttc ttccaaaacc gaactcaaac
     8221 gttcctcacc aacaaccatg ctcatcttga gcacaccacc aaagaggtca gatgttaatt
     8281 catccacaaa ttgcatccgt tggtagaatt tttcaatcat ttctggagtc ataaaacttt
     8341 caagatctgt aaaaatcgta ccttccttga caaaatcacc cttcatcccc gttacaacaa
     8401 actggtcctg acacgctcga cccttgaaat gagccaaagc cttgttgaca atggcgtcat
     8461 cccatgtctg agcctgaatc aattcattgt tttcaaaaat acgagcgcca ttagcaacaa
     8521 ccagaaccac tcgatccacc aagggactca gtagttgtct catgcggtga atttcattgc
     8581 ccgtcgcaat gacaaaacga atgccccttt gatccaactg atctaaaatc ttttccaatc
     8641 gtgggagatc aagctgacct ctagcatcca gcaaggtccc atccatatct gtcgcaatta
     8701 ccttaatcat catttacttt cctctggatt caagctaata ccacttcaat cccacatgtt
     8761 cattcatttc tttataggct gtatcaattc gttccttagt cgcttcatct aactggtcac
     8821 gatgactgcc atcctctata aaatcttcca aaatataagt ttggtaatga tacaagggat
     8881 atccttctgg tgaaaaggtt ccctttggtg ttcgattgac ccaagtagga tgagctttag
     8941 ctgttccgat agttgttttt ccatccttct tcttgatggt gacatccatg agaacaccac
     9001 gttcagtcca cttagcattc tcttcatctc ccatagattc aatccgttga ttggaaatga
     9061 agttccccat ttaatagata atgagtttct tatctccatc tttttcaacc gtttcagatg
     9121 gttcaacaac gtgaggatgc cctccaaaga taatatccgc tccccaatcg atcatcttgt
     9181 gataaagagc tttttgttct tcagttagtt ccaatcgata ctcaacaccc atctgaagca
     9241 tgataatggt gatatctgct tccttctctg cccgttcaat ttcaaccttc atcttatctt
     9301 cgtttaaatc tgaaagataa cgattatagt cttcctgaga aatatactgc tcaattccat
     9361 tgaaaccata ggaataggct aacaatgcaa ccttgatacc attcacttcc ttaatgacca
     9421 gcggagcctg atcacgtggt tcgtgcgtat aaactccgat tggagtgatt ccagctttct
     9481 caataatatc ggccgttgaa ataactccct caatttgcga atccaaaata tgattatgag
     9541 ctaaatccag cacatgataa cctgcctcct taatagcatc cataacttca gcaggagcat
     9601 taaagagaag ataacccgct aaataatgat ccttattaat ggttccttca aaatcaccaa
     9661 tagctaaatc tgctgcttag tccccttgct tgagccaagg agtcacatac tcaaaatttt
     9721 catgaaagtc ataggtaccg tcttcttttt tagctgaaaa gaaaagtcca tcgtggtaga
     9781 gcaaatcccc gtgggccata attctggcag ttttttcctc ttcctactcc tgagactttt
     9841 gcttagtccc ctcttgagaa atagtatctc gtttttgact agtcaaggga ttccttggaa
     9901 gctttcaaac aacaagacca agcccattga taaatcaact gctagcaaga gtatcgccac
     9961 aaatccctta ttgctccact tgcgataact cctaaaaagt ttaccaagcc cttcataaaa
    10021 cgaaaagcta aaccaccctg atttcgattt tgtcttcttt gtatcttcat tctccctact
    10081 ttcttatgca agccttttct ttttattata tcacagataa gtatttcttt cacaattgaa
    10141 ttgaacttcc catctatttt ctataaatcc taaatgccat aatgctttca attcttgtca
    10201 ttttgtgata tcatgtagag gaaatgaact aatccacagt ggcttattcc aagtatacca
    10261 cttgggcttt ggcagtagct aactgcacta aacataatat aaggagagaa aatgtctgca
    10321 atagaacgta ttacaaaagc tgctcactta attgatatga acgatattat ccgtgaaggg
    10381 aatcctactc tacgcgcgat tgctgaggaa gtcactttcc ccctatctga ccaggaaatc
    10441 atcctaggcg aaaagatgat gcaattcctt aaacattccc aagatcctgt catggctgaa
    10501 aaaatgggac tccgcggtgg tgttggactg gctgctcccc agttagatat ctcaaaacgc
    10561 attatcgctg ttttggtacc taatattgtt gaagaaggcg aaactccaca ggaagcctac
    10621 gatttggaag ccattatgta caatccaaaa atcgtctctc actctgttca agatgctgct
    10681 cttggcgaag gagaaggttg cctgtctgtt gaccgtaacg tgcctggcta tgttgttcgc
    10741 catgcccgcg ttactgttga ctactttgac aaagatggag aaaaacaccg tatcaaactc
    10801 aaaggctaca actccattgt tgttcagcat gaaattgacc acattaacgg tatcatgttt
    10861 tacgatcgca tcaatgaaaa agacccattt gcagttaaag atggtttact gattcttgaa
    10921 taaagaaaat cccgttgcaa gacggggttt tgtgttataa tagaggcatg aaaacaaatg
    10981 atattgtcta tggcgtccac gccgttaccg aagccctcct tgcaaataca ggaaacaaac
    11041 tctacctcca agaagatctc cgaggtaaga atgttgagaa agtcaaggaa ctagctacag
    11101 aaaagaaggt gtccatttct tggacatcaa aaaaatctct ctctgagatg actgaaggtg
    11161 ctgttcatca aggttttgtt ctacgagtgt ctgaatttgc ctatagcgag ctagattaca
    11221 tccttgcaaa aacacgccaa gaagaaaatc cacttctatt gattctagat ggtctaaccg
    11281 atccccataa tctgggttct atcttgcgaa cagccgatgc gaccaatgtt tcaggtgtca
    11341 tcattcccaa gcaccgtgct gtcggagtaa ctcctgtcgt tgccaaaaca gccacaggtg
    11401 ctattgaaca cgttccaatt gcccgagtga ccaacctcag tcaaacctta gataaactca
    11461 aggatgaagg cttctggacc tttggaacgg atatgaacgg tactccttgc cacaagtgga
    11521 atacaaaagg gaaaatcgcc ctcatcatcg gaaatgaagg aaaaggcatc tctagcaaca
    11581 tcaaaaaaca ggtcgatgaa atgattacca ttccgatgaa tggacatgtt caaagcctca
    11641 atgccagtgt tgctgcagcc attctcatgt acgaagtttt tctaaataga ctataaaaaa
    11701 gtttccagtc atctgattgg aaactttttt atgattaact atgttctgtg ataaacttgt
    11761 aggcttcttg accagcgata gctccatctc caactgctgt tgttacttgg cgaaggtctt
    11821 tcaagcgaac atctccaact gcaaagatac cgtcgactgc agtcttcatg tggctatctg
    11881 tcacaatcca gcctgcctga tcttggatat tcaattcttt aacaaaatcg ctaagagggt
    11941 ccaaaccaac atagataaag acaccaccga aggcttgctc tgtcacttga cctgttttca
    12001 cattttcaaa aacgacagat tctactctgt tttcaccctt gatttccttc actacagaat
    12061 cccagataaa gctgattttt tcattcgcaa aggcgcgatc ttgtaaaacc ttttgggcac
    12121 gaagttggtc acgacggtga acaatggtaa cagtcttagc aaaacgagtc aagaagaggg
    12181 cttcttcaac agctgaatct ccaccaccaa ctaccaataa atcttggtca cggaagaaag
    12241 caccatcaca cacagcacag taagaaacac cacgactgtt cagttcttct tctccaggca
    12301 ctcccaaagg acggtgttta gaaccagttg ctacgataac tgtacgtgtt tcatatgttt
    12361 ggtcatcagt catcactttc ttaaaatcac catggtcttc gacattttca acataaccat
    12421 aaatgtgctc aacaccaaga ttttcaagtg gttcaaacat cttttcagcc aattcaggtc
    12481 cactaatatt agcatatcct gggtaatttt cgatatcaga tgtattattc atctgaccac
    12541 ctggcagacc accttcaatc aaagctactt ttagattgct tcgagcagca tacaaggccg
    12601 cagtcatccc tgcaggtcca gcaccgataa taatagtatc gtacatatag attccttctt
    12661 tcttgttgta actatcttta ttctaactct ttcttgtcaa tcacgcaagg attatgcctt
    12721 gaaaacaaga attaaactca taaccgcaaa ggataatact gggacaacca agactccaat
    12781 cataatcata tcatagagat gggcttggcg agccccggct gtcttatcaa ctcccgacat
    12841 ggctctcaga ccaatccaaa tccctaaaaa aatcagaaca aggatggtgg tcaagatcaa
    12901 actctcgaaa tataaagaaa atagttgcag tagcatgatt tctctcattt ctatcttttt
    12961 taaagagtaa actcagctag tccaactaac tgagttttcc tttatctatt atatcaaata
    13021 taagtccgtt tgtaactagc aaagaattct tttgtccgct cttctttagg ggtgtggata
    13081 atctcatccg gagttccaga ctcgatgatt ttccccttat ctaagaagag aattttatcc
    13141 gcaacttggg ctacaaagga catgtcatga ctgaccaaaa tcatggtctg acctgactta
    13201 gcagcatctg caatagactt ttctacttca ccgaccaatt ctgggtcaag ggctgaagtt
    13261 ggttcgtcta agagcaaaac atctggtttc atagcaagcg cacgcgctag ggcaacccgt
    13321 tgcttctgtc cacctgataa atggcgagga taatggtttt cacggtccga aagcccaacc
    13381 ttagccaact cttccttggc aatcttagtc gcttcttggt cagataattt cttgacaaca
    13441 accaagcctt ctttcacatt atcaagtgct gttcggcgtt caaataaatt aaactgttgg
    13501 aaaaccatag acaacttacg gcgtagggca aggatttctt cttgagtgat tttagaaaaa
    13561 tcaactgaaa aaccatcaat ctgaatagag ccactgtcag gtgtttcaag ataattgaga
    13621 ctgcgaagaa aggttgattt tccagctcct gaagaaccaa tcaaggctac aacttcccct
    13681 ttttgaatat ccaagttcag atgatccaag acagtctgtc ctgaaaagga tttgcttaaa
    13741 ttcgaaatct taatcattaa cgaaggtctc ctttcacatc tgtttgcact gtatcaggtg
    13801 cagaaatagc catttttctc tcgatgaaac gaccgaggct ttcaattccg atattgacta
    13861 cccaataaac aagggcaacg gagatgaagc gttcaaaata gcgataatca gctccaccta
    13921 gaatctgagc ttgggcaaag acttccacaa cacccgcact aaaagctaga gatgttccct
    13981 tggtcaaacc gatgagggaa ttaatcaagg ttggagtagc taccaccgct gcattaggaa
    14041 taatcactcg tcgataaact tgcgctcggg tcatacccag actgcgcgcc gcctcaatct
    14101 caccaggatt aactgagaga atggctgcac gaatggtttc actagcataa gctgcctcat
    14161 taaaggcaaa agcgacaatc gcaaaagctg cagctggaat cgcattgata ttgagaccag
    14221 ttccccattg ctgattgagg gctttcaaag ccaaagggat tccgtagtag gtcaacatga
    14281 gttgcaccaa aatcggtgtc ccttttaaga aactaacaaa gaaggcctgc aagggatata
    14341 aaatcttgac acgattgatc ttcacaatgg caaaaagaag cgccaaaacc aagccaaaaa
    14401 gggcaccacc aattgtcaac ataattgttg ttggaagttg ttggacaatt ctagggattc
    14461 catcaaagac cgaacgtagg ctaaacagct tgccatccgg aatcaattgc atcaagtttt
    14521 ggtaccaatc tgatgctaaa atcgttgtaa cattcataaa aacatcctct tctgataatg
    14581 attcattcta ccatgcttct gccgtcaatg aaattatttg ctacggtcag atacagactt
    14641 tgtctaccta ctagtttatc atactttgaa acagggaagt tatatatttt atctatcaaa
    14701 gagatagata aaaactattt cagtcccagt tcttcataag attttcgata accgatttgc
    14761 ttaacagttc cattttctac taaaatgggc cgttttaaca acataccgtc acttgctagc
    14821 aactcagccg cttcttggtt tgacaaactt cctaccttat cttttagccc taattcacgg
    14881 tatttgatac cactggtgtt gaaaaattgc ttcaattcaa atcctgaggt ttctagccaa
    14941 ttcaaaatga cttcttggct aggtgtttct tccacgatat ggacggcttt ataatccaca
    15001 cttaattgat ttaattcttg ttttgctttt ttacaagttg aacatttggg gtattcgata
    15061 aattctaaca tgtgcttctc cttctatttg tttatatctt taaaatctac gccttcatgc
    15121 tccaagagcc aagctttctt ttccactcct gcagcatagc ctgtcagacg cttgcctgct
    15181 cccaacacac gatgacaagg tactaggata gaccaaggat tgcgtcccac tgctccacca
    15241 attgcttgag cagaagccac ttgcaggtct tgagcaattt gtccataggt cactgtctga
    15301 ccataaggaa tgccctgtaa atagtcccaa actctctttt caaaattcgt tccgattggc
    15361 gccaagagca agttggataa atcctgaggc ttgcctttaa agtaatcatc taagcaagca
    15421 ataactgggt ctaaaatagg atgactaaca acttcttcta tcgtttcatc tcctagtccc
    15481 ctctcaaaat gcttctgctc ctgaacccaa attccataca aataatggtc atcagctaca
    15541 agtgatagaa taccaattgg tgaggagtag agtattttta catacttctt ttgcattatt
    15601 tctttaattt ttgataggcc aagcgttcgc catctactgg caccttacca acttgtttaa
    15661 aaccaagttt ttcaaaaata tgttgcataa ccttgttttc agcatgcgta tctgagcgaa
    15721 aatcaagata atcaaaacct tcaatcaagc cctctaagaa ggtttgagca actccttttc
    15781 cctgcacatc tgctgccaca gcaatacggt gaaagactag atactctgac tctccagctt
    15841 gccagtttcc ctcataaata gcttcatagg cctcctctgg actcttggtc acagcagcat
    15901 aggctagcag ttctccctct tccaaggcta cgtaggcttg ccctgagatg atatcatcga
    15961 taataacatc tgcatttgga tagccatttt gccactggtc actaccagca tctgctaaac
    16021 attttttggc atcctccatc acctgcatga tggcatctac ttcatttgga aaagctaaac
    16081 gaatttccat cttttttcct catttctgac tagtttctcc catcatagca taatttaagt
    16141 atttctacaa gcagttaaaa cttgactttg tgtttttgtt attttataat ctagttatca
    16201 aaactatata aaaaggagtt gaaaatgaaa actacctttt cctacccaaa atgggcagaa
    16261 attccaaaca ttgacctcta tctggaccag gttttgctct atgtcaatca ggtctgcgcc
    16321 cctatctctc ctaataaaga caagggccta acagcatcta tgatcaacaa ttatgtgaaa
    16381 aatggttacc tgacaaagcc tgacaaaaaa aaataccaac gccaacagat tgcccgtttg
    16441 attgctatca caaccctcaa gtctgtattt tctattcaag aaatagccca gacacttaat
    16501 actctacaaa ctcaagcaag ttcagaccaa ctctacgatg cttttgtgga ctacatgaac
    16561 caaggaattg acccagctaa ccctattatc caaaccagct gccaaaccgt taaactctat
    16621 catcaaactc tagacttaat cgatcatact caagaggagg taatccaatg aacactagtc
    16681 ttaaactcag caaacaactc agttttggag aggagattgc taatagcgtg acccatgctg
    16741 tgggtgcagt catcatgctt atcttgctgc ctatttcatc catctatagt tatgaagcac
    16801 acggattttt atcctctatc ggcgtttcca ttttcgtcat cagtctcttt ctcatgttcc
    16861 tatcatccac catttatcac tctatggcct atggttcgac ccacaaatat gttttgcgaa
    16921 tcattgacca ttctatgatt tacgttgcca ttgccggctc atacacgccc gttgtcttga
    16981 ccttgatgaa taactggttt ggctatctga ttattgtcat ccaatgggga acgaccatct
    17041 ttggtattct ctataaaatc tttgctaaaa atgtcaatga gaaatttagc cttgctcttt
    17101 acctgattat gggctggttg gttctggcta tcattcctgc cattatcagt caaacgacac
    17161 ccgttttctg gagtctcatg gtaactggcg gactctgtta tacagttgga gctggatttt
    17221 atgccaagaa aaaaccttat ttccacatga tttggcatct ctttatccta gctgcgtccg
    17281 tacttcaata catcgctatt gtttattaca tgtaaaaaag ttgagaaatt caatctcaac
    17341 ttttttcttt acacatattg ataaagtact ggtgcaagcg cacatcatca gtcaattctg
    17401 gatgaaaaga acttaccaac atattttttt cttgggctgc aacaatttga ttgttcactg
    17461 ttgctagaat ttctacaccc tcaccaacac tactgataat cggaccacgg ataaaggtca
    17521 ttggaatctt gccaactccc ttacattctg cttccgtgta gaaacttcct aattggcgcc
    17581 cataagcatt acgctcgacc accatatcca tagttcctag ataactctct ttctgagaag
    17641 tgatttcctt agccagcaaa attaagcccg cacaggtccc aaacactggt aagccagata
    17701 gaatggcttc tcggatgaga agtagcatgt tctggtcacg taagagcttg cccatggttg
    17761 tagactcacc accaggcaaa atcaaacccg acaagtcact ctgatcttgc tgaaaatcat
    17821 ctagatttct gagttctaca ctctcgacac ctaattgatc tagcactttt gcatgttctg
    17881 caaaggcccc ttgcaaggcc aatattccga ttttcatcta ttttcctcgt tcagccatga
    17941 gaatttggat ttcattttca ttaataccaa ccatggcttc tcctaaatct tcagagattt
    18001 gagctaggat ttgaggatta cggaagttag tcacagcctt aacaatggca ctcgctcgtt
    18061 taacaggatc tcctgacttg aaaatacctg aaccgacaaa gaccccctct gcccctagtt
    18121 gcatcattaa cgcagcatct gctggcgttg caacacctcc agcagcgaaa tttacaactg
    18181 gcaattttcc atgttcatga acatattgga ccaattctac agggacttgc aaatccttgg
    18241 cagcaacata aagctcgtcc tcacgtaagt tttgaatgcg gcgaatttcc tgattcatca
    18301 tacgcatatg acgaacagct tggacgatat cccctgtccc tggttctcct ttggtacgaa
    18361 tcatggaagc accttcagcg atacgacgca aggcttcacc caaatcctta gcaccacaga
    18421 caaaaggaac ttggaattct ttcttgtcca catggaaacg gtcatcagct ggagatagaa
    18481 cttcactctc gtcgatataa tcaatttcaa tagcctctaa aatctgagct tcaacaaaat
    18541 gcccgattct gaccttagcc attactggaa tactaaccgc ttcttggatt tccttaatca
    18601 tctttgggtc gctcatgcgg gaaactcctc cagctgcacg aatatcagcc ggaattcgtt
    18661 ccaaggccat cacagctgcc gcaccagcag cttctgcgat acgagcctgt tcaggattct
    18721 gcacatccat aataacacca cccttgagca tctgtgccaa gtttttattt agttcataac
    18781 gattttcagt catttgtttt atcctcatca tttgtattgg tagctacctt ttcattttaa
    18841 gtcagaacag aatgaagcac aagataaaaa aactataatt gtatggggac aaattagcta
    18901 aaaactatct gaccttaact taaggccaga tagctcattc atttttattt ttcagccgta
    18961 agggcagcca ttgtgatgta gttgtatggt ttgttgaagt gtggcaagaa gaagaggtct
    19021 gtcaatgcca atttatcaat tgtcacatgc tcttggatag caagtgagaa catgtggatt
    19081 cccatgctaa ttgcaatatc atgtgaaacc atttgggcac caagaatttc acggctatct
    19141 ttgtcaaaga caatcttaat tgctacttca tggttgtcat gtttcatgaa ttctggtttt
    19201 tgaagatcgt taaagcctgt ttcagttgcg ttgtaaccag cagctttcgc tttttcaaga
    19261 gtcaaaccag ttgaaaccat gtgaagaccg tagattgaga taccatttga accttgaaca
    19321 ccgattcctt ccaattcatg tccacaagca ttgtaggcac caacgatacc agtgcgaaca
    19381 gcatttgaag caagagcgat atagcttgta tctttacgag cattgtcata aacagtcgca
    19441 cagtcaccaa cagcgtaaac gcctgggata gatgtttctt gtttcttgtc tacaaggaag
    19501 gcaccgttgc ggaagagttc gatcttacca tctgcaaggg ctgtgtttgg acggaaacca
    19561 actgcaagga taaccatatc cacgtcaaag ctttctttgt cagtaatcaa gcgttcaact
    19621 ttaccgtcac cttcgattgc tttaacagtt tgacctagag ccaagcggat gttgtgatct
    19681 tccaagttct tcgccatcat ttgtgtgaag tctttgtcat agtaaccgtt caagacagta
    19741 tcaacgatat caacaaggac aacttctttt ccaagacgtt caaaggcttc agcaagttca
    19801 acaccgatgt aaccaccacc aacaacggcg atacggtcga ggtgttggct cttgtcagaa
    19861 agtttattga taacttcttc agcattttgg tacaatttca cgaattgtac gttttcaaga
    19921 gttgctttaa attcgcggtt tcctttaaca atttcaacac cttcgattgg tggcaagatt
    19981 ggtgtagaac ctgtagcgaa aatcaatttt tcgtatgatt ctttgtgctc ttttccttca
    20041 acttccgctg taactacttt gttatcatag tcgattgaaa gaacaggtga gttcatgtaa
    20101 actttagcac ctttagcttc caatttttct ttatcagaat agaacaagcc ttcagcaccg
    20161 tcaatttgtt caccaatcca aagagccatt ccacatccta ggaaagagat gttagagttt
    20221 tggtcaaata caacaatttc gttctcattt ccaaaattat ccaacatggt attgatacat
    20281 gctgtaccag cgtggttagc accgactaca acgattttac tcataaaaat ttcctgcctt
    20341 cattctaaat ttaccttact agtataccat ttaccgttag cgtttacaag gggggtacta
    20401 ttatttcagc attttttatc aaaaataatt ccccatttat cctgttttca agcctcatga
    20461 attttatgag catatttctt gactttttcc aaattttgtt tgtgaaaatt ctaactttat
    20521 ggtattataa taacatgaaa atgaaatgta agggcttcaa tttagatgat tatttgatat
    20581 tacaacttat tttctataag agaaaggagt tggtagcttg actcttcgtt cacattctga
    20641 acggctaatg gggactacta tcactatttc attagtggat gagcaagccg atatctttct
    20701 ccaaaaatcc tttgacttgc tcaaagagct tgaataccgc ttcaacgcca atagtcaaga
    20761 atctgagttg atggaaatca attatcaagc aggaatatcc cccgtcacgg ttcatccaga
    20821 cctgtttgag ctgatttcac ttgggttaga gcatagccta gcgctctcta gccacctcaa
    20881 tatcagcatt ggtcccttaa ttcaaacctg gcgtatcggt ttttcagatg ccaaggtcgc
    20941 ccagcctcaa gaaattgaat cggtgctgcc tctaatcaat cctcatggta tcgagttaga
    21001 ttcttctact tctactgtgt ttttaaaaca gaaaggaatg aagatcgatc taggttgttt
    21061 agccaaagga tacagtgcgg ataaggttgc ccaatttctt aggaaagagg gggtgacttc
    21121 tgccttgatc aatctgggag ggaatatcct gaccattgga aaaaatcagg caagagggga
    21181 taacccatgg caaatcggga ttcaagaccc agccaatccg aggggaaatc atttaatgac
    21241 catccctgtt gtcaataaat ctgtcgtgac ttcaggcatt tatgaacgtc acctgaccgt
    21301 cgatggacaa gattaccatc acatttttga cagtcaaaca ggatatcctg ttgaaacgga
    21361 actagcgagt ctaacaatca tctctgataa atcagtcgat ggcgaaatct ggacgactcg
    21421 actctttgga gaaagacctg cttctatctt ctggcaagtc gaaagtttgg agggcatcga
    21481 agtcatcctc atcgataaag aaggccacct aagctgttct tcaggaattc ctactctata
    21541 gagacaactg tttcaatgga attttaaaat tgtattatgt aaaaagagaa aggaaatctc
    21601 atgttaaaac ttattgctat tgttggaaca aattcaaaac gttctacaaa ccgtcaattg
    21661 cttcaataca tgcaaaaaca ctttgctgac aaagctgaaa ttgagcttgt tgaaatcaag
    21721 gccattcctg tcttcaacaa accagctgac aagcaagtac ctgctgaaat attggaaatt
    21781 gctgctaaaa tcgaagaggc agatggcgtt attatcggta ctcctgagta tgatcactct
    21841 attccagctg ttttgatgag cgctcttgct tggttgtctt atggtattta cccacttttg
    21901 aacaaaccaa tcatgattac aggtgcttct tacggtacgc ttggttcatc tcgtgcccaa
    21961 ttgcaacttc gtcaaatctt gaatgctcct gaaatcaagg caaatgttct tccagatgaa
    22021 ttcttgctct cacactctct tcaagcattt aacccaagtg gcgacttggt tgaccttgat
    22081 gttatcaaga aattggatgc catctttgat gacttccgta tctttgtaaa aatcacagaa
    22141 aaattacgta atgcacaaga attacttcgc aaagatgctg aagactttga ctgggaaaat
    22201 ttgtaagata ggagaccaaa aagaatgaaa tttgttggac ttgttggatc aaactacgat
    22261 caatcatata accgtaagct cttggaattt atccgtcgct acttcaaact caaatttgaa
    22321 ttagaagttc ttgaaattga cgaagttcca atgtttaacc aagatgaaaa atgggatgaa
    22381 agtttccaat tacgttattt atataacaaa attactcgtg cagatggtgt tatcattgct
    22441 actcctgagc ataaccacac tatctcagct tcactcaaat ctgtacttga atggctttca
    22501 tacgaagttc atccatttga aaacaagcct gttatgattg tgggtgcatc atactatgac
    22561 caaggaacat cacgtgctca agttcacctt cgtaaaatcc ttgatgctcc aggtgttaat
    22621 gcctacacgc ttccaggtaa cgaattcctt cttggtaaag ctaaggaagc ttttgataac
    22681 aacggaaata tcaccaacga aggcactgtt aaattccttg aaacttgctt agataacttt
    22741 gttaaatacg taggagtcgt ttcgaaattg aaaaaaccaa aaccaatcga atcagaagac
    22801 ttggattgtg gaaaaccaat cgctacaacc atcacagaag ttgaccctga cgatccagaa
    22861 tgggtagaaa aagttgcagc aatcactggt gctgtttctg gtgataccta tgtcaaattg
    22921 gaccacggta tcctaacagt taaccaaatt gatatgttct tgaaagctat gccatttgaa
    22981 ttgacatacg ctgacgacaa caaccaattc ctctactaca acaacgctca ccaagatcca
    23041 gacactatgt tcgctaaacg tgtaccacct caatcaggta gccgtatgtc gactgttcat
    23101 ggttctcttc caccagcacg tatgaagaac gtagagtggg ttatcggaac acttcgcaac
    23161 ggaaaccaag aatacgtccg tacgatcgtt ccaggttctc ctgcaggtgt tatcaacact
    23221 cacaactacc aagcaatgta ctatcctgat ggatcatacg ctggtatcaa tgaaatcgtc
    23281 tttaacttcc aaccatggct tgactggtac ctaaaagaga ctggtcaacg tttggtgggt
    23341 ggtagcggac catttgctcc tgctgccgga ggtcatggag acgccgatgc tacttctggc
    23401 gcttctgatt caggggatgc tggatgccac ggtggtgacg cagacgctac agccggtgca
    23461 agttactaat gatagttttt aggaaccatt atggttcctt tttagcgaaa aaagactagc
    23521 aaacacaaac tgctagtctc tttgttatcg tttcatctat ctttgttaaa agaaagaata
    23581 catattatga atttggatca tcaagactac ggccatgtaa tcctttttca cgttgtactt
    23641 ggcgtagttt ttctggtgta acatcgtttc cttcttcgtc cacaattttg attccttcaa
    23701 tgtggtgacg aacagcgcgg cgataacctt cgatgtactc ctcacgtagt ttggcttgtt
    23761 ccactttttc ttctggtgtt aagccttctg tttttttctt tttagcaagc tcattgatac
    23821 gagcaatttt tttcggatcc atttcttctc ctctgtaata agataaagtc cgtttatcaa
    23881 attttattta gtgttaattt ggttaaaaca agcaaactta gctgctttct tggttagttg
    23941 tgacaagatt gccaaacgat tttgacggac agcctgatct tcagccatta ccatagtatt
    24001 ttcaaagaaa gcatcaatga ctgggctaag cgcaaagagt tgtttcaatt gctgacttgc
    24061 aggtcctgat aaaacgagtg tttctactgc ttctgccaaa gctttttctt ggtcattctc
    24121 aaatagtgct gaatcaactg tagcaacccc ttctgccttc tcagccaggt taaaggcacg
    24181 agaaagtgat tcaacagatg gtttaaaatc ttcttccttg cttacttcta cgagagcact
    24241 tgctgcttcc aacatatctg ccacaacaaa gtttgaacct gcaagaactg cttccttgat
    24301 atcttttgga gtagagccca tcatcttatc aacacgagcc ttgataaagt ccataacctc
    24361 tgctttattt tcataagtca aactgtcaaa tttcaatgca taaaggctat caatcagctc
    24421 atccatagca atgtgccaac caaaggcatc caagatacga accacacctt gagttgcacg
    24481 acgaagggca taagggtcat tagaacctga tggaatcaat cctactgaga agaaactcaa
    24541 aatcgtatcc aatttgtctg caatggctag aactgcaccg accttgctct ctggaagttc
    24601 tccttcagct gatgtaggca tgtagtgttc acgaatagca gctgccaccg ctggagtttc
    24661 accagcaaga agggtgtatt tttcacccat aattccttgg agttcgtcaa attcaccaac
    24721 catacctgtc aacaagtcaa acttgtaaat ggctgctgca cgagcaaggt caactgtttc
    24781 atccactgac aaaccagctt tttctgccaa aagtacagtg atttgacccg tacgaatcat
    24841 gtgttcacga agggaaccaa tcttctcatg gaaggtgaca ttgtttaatt tttcaacaag
    24901 atctgaaatc accaattttt ggtcttcacg ccagaagaat tctccgtctt ccaagcgggc
    24961 taccaagact ttttcatttc ctttgatgac atttttcaaa cgctctgcgt ttccgttacg
    25021 aacagaaatg aagtttggca agagttttcc atcttgatca cgaacaacaa agtaacgctg
    25081 gtgttccttc atagaagtca ccaagacttc ttctggaact tcaaggtatt tagcatcaaa
    25141 acttcccatg aaggcagttg ggtattcaac caaattcaag acttcattca gcaaatccgc
    25201 atcaatttcg atacgtacac catgttttgc ctcaattttc ttgatttggt caacaatcat
    25261 ttgctcacgt tcacatggat ctgcgattac aaactgctta cgaaggtctt cttcatagct
    25321 caatgctgac tgaattttgg tttctttccc caagaaacga tggccacggc tcacacgacc
    25381 tcccttgata tcaaggaaat ccaagtcaaa ctcttgctca tccaagagaa cagttaaagt
    25441 gtgaacaggg cggatgtatt caaagctatt tccagcccag tgcatgctga cagggaaagt
    25501 caatgacttc aagacatcta caacaccagg aacaatggct tcaactgctt gaccaacttc
    25561 ttccttagtg acatagacat attcttcacc cttgatttca cggaattcga tatcttcaac
    25621 agtcaagcct tttccacgga caaatccttg agctgctttg gtgaagtttc catcactatc
    25681 caaggcaatt tcctttgctg gtcccttgaa atcttctgtc aaatcagact gtttgtctga
    25741 taaaccagtc acacgaacag ccaaacgacg tggtgttgag aaggtttgaa tggcttcaaa
    25801 agacaggcgg ttttccttga ggaaggctgc cattttttcg cctagttgtt tttcacttgg
    25861 tgtgacaaca taggctggta attcttcaag accgagttct actaataagt tttttgtcat
    25921 gttttttctc cgaaaagtat ctttttattt tccagtttgc cttatgtgat tggcacgcaa
    25981 gcaaccaact tcgttgtttc attgctaaaa ttggagccaa aagtctccaa ttttgcctag
    26041 tatccttagt ttcactaagg ataccttcat cactgcggca actgactcag ggctcactct
    26101 gttcgcccat tttcgtaatt tgtcactctc tttattctgc gtcttctgct aggagtttag
    26161 ctcttgtttc ttcatccaaa agtgggtaac ctaggcgttt gcgttctgca acaaaggttt
    26221 tggctacaac acgggccaag ttacggatac gagcgatata gcctgcacgc tctgttacag
    26281 atacagcacc acgcgcgtca agcagattaa aggtatgtga acatttgaga acatagtcat
    26341 aggcagggtg taccaagcct tcttctaatg cacgaccagc ttctttttca aacttatcaa
    26401 agttttcaag caacatttct tggtccgaaa tttcaaatga atattttgag tgctcatact
    26461 caggctggat aaagatttct ccgtatttta caccatcagc ccactcgata tcatagacag
    26521 agtctacttc ttgaatgtaa gaagccaagc gctccaaacc ataggtaact tccgcagtca
    26581 cagggccagt tgccaatcca ccgacttgtt ggaaataagt gaactgagtg atttccattc
    26641 cgtcaagcca aacttcccaa ccaagaccag ctgaaccagt tgatgggttt tcccagttgt
    26701 cctcaacaaa acgaatatcg tgctccaaag gattgattcc caatttttcc aaagactcaa
    26761 ggtaaagttc ttggatattt gatggagaag gcttcatgac cacctggaat tggtggtgtt
    26821 ggtagagacg gttagggttt tccccataac gaccgtcagc aggacgacgt gatggctcta
    26881 cataagctgc attccatggc tcaggtccga tagcacgaag gaaagtgtaa ggactcattg
    26941 ttcccgcacc tttttcatta tcataagcct gcataagcat acaaccttgg tcattccaaa
    27001 attgttgcaa agtaaggatg atttcctgga aagtcaattt cttagacatt gtttactcct
    27061 ttttatataa attacttgcg acatgagtct gcctcgtcga tcatacgagg caagacgagt
    27121 tagtactgcg tctagctcag gcactctagt gctgagcgtg gggcagtccg actgtaagga
    27181 ggtttctgcc actgatgcag taaaatgtta atttcttaga cattgaatac tccttaataa
    27241 aaaatgattt cttgcgacac gagtctgcct cgtcgattat acgaggcaag acgagttagt
    27301 actgcgtcta gctcagcacc ctagtgctga gcgtggggca gtccgactgt aaggaggtct
    27361 ctgccactga tgcagtgaaa tgttaatttc ttagacattg tttactcctt tagtttttat
    27421 atttcttttt caattaattt ctgctgaaca aaccaatcta acaagggaaa aattttttct
    27481 gtatttgccc ataaatgata agaatctaag accgcttgta cactacctaa attttctacc
    27541 aacttatcta ctgtcaaaaa gcttcgccag tattcataaa aaatacttgc atagttctta
    27601 tcataagtcg aagaaccaaa atcattcaat gaatgccaac catacttctt ctgaaaaagt
    27661 tctacgagag attgattaca aattttttcc gcttgaaatt cctcttctgt aaagaaatac
    27721 ttgcgactaa tatattcaac catcccctct tcgaaccaga tataagagtc ataaccatca
    27781 aaatcatcta aaaaatgctc cgaccaatga gctaactcat gtcctacaat ctgtaagagg
    27841 aaattttcag ataaagaatg atagtgactt tctattgctt gagtttgctc agaacactcg
    27901 tagtccatca attgatacaa atacaactct ttccaaacag ctaaatcagg cgccataacc
    27961 attcgtctat tatttgtata ggctggaaca gcgctttccc taataatctg tgtagcagca
    28021 ttaaaatctg accaaataac ggcttgcggt aaatcacaga ctgcaagttc attctttaaa
    28081 aaagattgat aatctttcaa cttttcagta tttcttacta caaaatcacg aaatgtagct
    28141 agttgactat cgtcttttac aagataaagg ttgtccacgg ctctcctttc tttcacacaa
    28201 tagactgaat aagcaaaaga accgcgtccg acaatcctag gttgatttaa cctaggggcg
    28261 tcagaaacgc ggttccaccc taatttatta cttcattgtt tttgaaaata ctacagaaag
    28321 cgccagctca ttattttgcc ctacttggct cccactatcc caagctcgct tgaagaacgc
    28381 cataagactt tctttcctgc tgactattat atcaaaaatt agaataatgt acaattcttt
    28441 ttatgatttt ctagaaatcc acatcatcaa ctcgtggagc acccgattga acagcaatcg
    28501 tttttaaggt ttctctctcc tcatgactca gttcaattcc aaagcaatca agattagctt
    28561 gaatacgaga ggttgtgaca gattttggaa gtggtaaaaa tccttctgcc aagctccagg
    28621 ccaaggctat ctgagcaatc gattttccgt gatttgctgc gatttcttgc acttgcttgc
    28681 tatcaaatag ttctccctga ccaaaaggcc cccaagcttc caataaaatt cccttttcac
    28741 gacagtaagc tacgacttga tcttgataca cacctggcgc caagcgaact tgattgaccg
    28801 caggaacgat agttgcagtt tcaagcaagg catccaaatg atggggaaga aaattgctaa
    28861 cgccgatagc acggattttc ccttcttgat agaggtcttc catcgctctc caaacttccg
    28921 cattgcgagt tttccatgcg tcattttctc tgagcggttt tgggttcggc caatgaatca
    28981 aatacaaatc caaataatcc aagcccagtt tttctataga tttttccaaa gcttgacgag
    29041 tttgctcata ggtttgctga ctattccaaa gcttggtagt tacgaacatt tcttcacgtg
    29101 gaactccgct atctttgatt gcttgaccaa cactttcttc attctgataa atcgccgccg
    29161 tatcaatatg acgataacca gccttcaagg cttctaacac tgcatgatag gcttcttctc
    29221 catccttagc cttaaaagtt ccaaatccca atactggaat ttctactcca ttatttaatt
    29281 gataggtatt catatgcttc tccttctatt ttattcatca attatagcat aagacatttt
    29341 ttaagtagta ctatcttctg taaaaaataa gtctgtcaaa tatctaacag acctattttt
    29401 tcttgcttat tcatcacgac tatagtacag ctcatgagct tttaggcgag tattgagcat
    29461 ctctggtatg gtcacaaagg tataaccttg atttttcaaa tactcaatga cccttggcaa
    29521 ggcattgact gtcggactgt gaatatcatg catcaaaacg atagagccgt tagctacttg
    29581 atgctgaatt tctgtcaaaa tagatgcttc atttttactc ttccagtcca gactatccac
    29641 atcccacatg ataaagctca aatccaagct attgcgaata tcatctgtaa tagcaccata
    29701 aggtggacgc atgagtttag aactagaacc cagcacttta gttagcacat cctcagtatc
    29761 agtaatctgc tttttagctt catcaagaga gagttgcgag agaatcggat ggctccaact
    29821 atggtttcca acaacatgac cttcagattt tatcctcttc accaagtcct cattcccaga
    29881 aacatttttc ccaagcacaa agaaagtcgc tttaatatca tatttagcta gggtctctaa
    29941 tacctgcggg gtcgttgctg gatttggacc atcatcaaag gttagagcga caactttttg
    30001 atatttctta tcaaagtaag attgatacaa ggccgcatct ttttcgagta agtacgaaga
    30061 ttggataaca tcaaagaaag cagatactgg caaggctatc tcttctaaat tttcaagcac
    30121 aggacttgaa taaaggataa tctgactatc cttgtaatca aaattccatg cagacaagtc
    30181 ttggtcagag aagcttttta caatctgctc actctggtct tgctctattt ttttatcctc
    30241 tatgaaggag gtcaactctt ttatcagctg ttccttagcc ttactagcat ctgaaaacag
    30301 ttggtcaagt gtaaaaggtt gcccatcttc tgttaagtga acctttccta gactggtctt
    30361 ttcagtctct tcaaccttaa aagcaactaa atcatagatt tgtttggtca cattacgatt
    30421 aacgactccc tttaaacctg actcttcttg ctctgtatag tagaaaacaa gattgtcctt
    30481 actttctagc ttgtccttaa catcttgatt tatcaactcc ctaacagagg aaatcacttt
    30541 ctccccttgg agaggataat aggcaatcac ttcggcttgc ccctgacgaa aatgctcctt
    30601 ctgatttccc tcactcaatt gatcatcttt ctcttttttg agcgattcaa tcttttgctc
    30661 aaaacttttt tgctggtaga tcttaaaagc aataaatccg cctaataggc aaatagaaat
    30721 tgctaagata ccaatcaaag ccaataatac atgtctcgtt ttcccgtgtc tgccacgtcc
    30781 tagtctactt ttattcatat ttatatcata acaaatttga gcaataattt caatgataca
    30841 atttggcaat ccacaattcc tctagcaagc caaagcatct tacatcaact ccaacatccg
    30901 tatctgtaga gattatgtag ttttctatct atggaatttc tagtaaattg aagctagaat
    30961 agtagaccta tacttctaaa acattgttag aaatcgattt gattgtcctg atcgatttgt
    31021 cctgttctta tttcatttta ctataaaact atgaaaagct aggtcatctg agaagtaatt
    31081 actatcgaca attgcgatag cgtatactgg tgcgatttgt ttgtagctct ggtgggtatc
    31141 accttcacgt tggcgaattt tttctaggtt ttgattaacc tgactgcaca gataagccca
    31201 taggcgattg atgaaaaaat tctgatgatg aacctgaatt tcgatgataa cttgaattcc
    31261 attatctaac tccgccaaga cgtctatact agtatagaaa tcctgcgctg agtaggacat
    31321 ggaaggcaag acgtgaatgt tacttccctc caaaatcgtc acattttttg ctggcaagtc
    31381 cagcatatcg cggataaatt gacaaatcat tagttgggct gatacccgga tgtctgagaa
    31441 tcctcctttt cctccttcta ttatagcaca tttttaaatc taggtttgct agattctatg
    31501 cttctatcta tttattcgga aaagaaagct tttcttcaga agaaagctaa tagcttattt
    31561 gaaattttct cctctctgtt ggatagtccc gtctatctat gttataatga aagaaggatt
    31621 taaaatcgga aaaggagtat ttatgctaaa attaggtgtc atcggaactg gcgctatcag
    31681 ccatcatttc atagaagcag cccataccag tggagaatac caactggtcg caatctattc
    31741 tagaaaacta gaaactgcag caacctttgc ttctcgctat cagaatatcc aactattcga
    31801 tcaattagaa gtcttcttca aatcttcttt tgatttagtc tatatcgcca gtccaaactc
    31861 cttacatttt gctcaggcaa aagctgcctt gtctgctggt aaacatgtta ttctcgaaaa
    31921 gccagctgtc actcaaccac aagaatggtt tgatttgatt caaacagctg aaaaaaataa
    31981 ctgttttatc tttgaagcag ctcgtaatta ccacgagaaa gcctttacta ctatcaaaaa
    32041 ctttttagca gataagcaag tgttaggagc agatttcaac tattccaaat actcttccaa
    32101 gatgcctgac ttgttggctg gacaaacacc aaatgtcttt tcagaccgtt ttgctggtgg
    32161 agccctcatg gatttgggga tttatcccct ctatgctgct gttcgtcttt ttggaaaagc
    32221 caatgacgcg acttaccatg ctcaacagct tgacaatagc attgacctaa atggagatgg
    32281 taccctcttc tacccagact atcaagttca catcaaggct ggaaaaaaca tcacttccaa
    32341 tcttccttgc gagatttata caacagatgg aaccttgact ctcaacacga ttgagcatat
    32401 tcgctcagct atttttaccg accaccaagg aaatcaagtc cagcttccta tccaacagga
    32461 tcctcatacg atgactgagg aagtcgctgc atttgcacac atgatccagc aaccagatct
    32521 gaatctctac caaacttggc tgtatgatgc aggctctgtt catgagctac tatataccat
    32581 gcgccagact gctggcatta gatttgaggc agaaaaatga aaaccaaact accgactgaa
    32641 tggcaagaac tgagtgacca actcggtttc caagaattca ccctcattca aactcaacta
    32701 tttgagcccc ttcttgctgg agaaaacctc ctaggagtga gccaaaccgg aactggtaag
    32761 accctagcgt atctcctacc aagtcttctc agactacaaa agaaaaaagc ccaacaactc
    32821 ttgattctag caccaaatac ggaacttgct ggacagattt ttgatgtatg taaaacgtgg
    32881 gcagaagcta tcggattgac tgctcaactc ttcctttcag gttcaagtca gaaacgacaa
    32941 attgaacgcc ttaaaaaggg gtcagaaatt ctgattggaa ctcctggccg tatctttgaa
    33001 ctcattaaac ttaaaaaaat caagatgatg aatgtggaaa ccatcatcct ggatgaattt
    33061 gaccaattac tagatgattc tcagattcac tttgtagaaa aaatcactca ctacgcacct
    33121 cgtgaccacc aactggtcta catgagtgcc acgaccaagt ttgaccaaga aaagattgtg
    33181 ccgaatacac gcactattga tctctctgat caaaaattgg acaatatcca gcatttctac
    33241 atgcaggtag accaacgtca tcgagtggat atgctacgaa aactggctca tgtagaggat
    33301 ttccgtggtc tagtcttctt caatagcctg tcagaccttg ggaatgccga ggaaaaacta
    33361 cagtatcgtg atatattggc tgtttccctc gctagtgatg ttaatgttaa atttagaaaa
    33421 atcatcttag aaaagtttaa agataaccaa ctaaccctgc ttcttgcaac tgaccttttg
    33481 gctcgtggaa ttgatatcga tagcctagaa tgtgtcgtaa actttgatat tcctagagat
    33541 agcgaaacct acacacaccg tgctggccgt actggtcgta tgggcaagga aggttatgtt
    33601 atcactctcg tcactcatcc agaagaaatc aaaaaactta aaaagtttgc aagtatccga
    33661 gaaattgtcc taaaaaacca agaactctat atcaaataaa gccctattgc tctatacaca
    33721 tccagtgtat ggagcttttt tataagcaat tcaattttat actcatctgc tttcaaaaag
    33781 cattctagtc catttccgat taacgatgga ctttatcacc tccttctcca gtccttgtat
    33841 gacatcttcc aaagttcgaa aggctttatt cttaaatcca cgtttacgaa tctctttcca
    33901 cacttgttca atggggttca tctctggtgt gtatggagga ataaatgcaa agccaatatt
    33961 agtcggaatc tttaaggtac ttgatttatg ccatatagca ttgtc
//
LOCUS       DBEJKC010000020        33330 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.020, whole genome shotgun sequence.
ACCESSION   DBEJKC010000020 DBEJKC010000000
VERSION     DBEJKC010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 33330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33330
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.020"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(40..924)
                     /locus_tag="ACL3G6_000953"
     CDS             complement(40..924)
                     /locus_tag="ACL3G6_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGR0545507.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(1069..2220)
                     /locus_tag="ACL3G6_000954"
     CDS             complement(1069..2220)
                     /locus_tag="ACL3G6_000954"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HGR0545508.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(2366..4132)
                     /locus_tag="ACL3G6_000955"
     CDS             complement(2366..4132)
                     /locus_tag="ACL3G6_000955"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008736 - L-fucose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019317 - fucose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HGR0545509.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTEHPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRS
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYCACQLLGPLHK"
     gene            complement(4215..7331)
                     /locus_tag="ACL3G6_000956"
     CDS             complement(4215..7331)
                     /locus_tag="ACL3G6_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 98 C-terminal
                     domain-containing protein"
                     /protein_id="HGR0545510.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVSFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKEDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNDYEVFTQHIDSLESNNLSIDLKGLKGKKVRISLRSAGIPLSLA
                     EVEVYTYK"
     gene            complement(7341..9635)
                     /locus_tag="ACL3G6_000957"
     CDS             complement(7341..9635)
                     /locus_tag="ACL3G6_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGR0545511.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            complement(9694..10494)
                     /locus_tag="ACL3G6_000958"
     CDS             complement(9694..10494)
                     /locus_tag="ACL3G6_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0545512.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            complement(10491..11264)
                     /locus_tag="ACL3G6_000959"
     CDS             complement(10491..11264)
                     /locus_tag="ACL3G6_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR0545513.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            complement(11289..11759)
                     /locus_tag="ACL3G6_000960"
     CDS             complement(11289..11759)
                     /locus_tag="ACL3G6_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0545514.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            complement(11750..12181)
                     /locus_tag="ACL3G6_000961"
     CDS             complement(11750..12181)
                     /locus_tag="ACL3G6_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0545515.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            complement(12174..12614)
                     /locus_tag="ACL3G6_000962"
     CDS             complement(12174..12614)
                     /locus_tag="ACL3G6_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HGR0545516.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            complement(12626..13264)
                     /locus_tag="ACL3G6_000963"
     CDS             complement(12626..13264)
                     /locus_tag="ACL3G6_000963"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HGR0545517.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            complement(13379..14782)
                     /locus_tag="ACL3G6_000964"
     CDS             complement(13379..14782)
                     /locus_tag="ACL3G6_000964"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase family protein"
                     /protein_id="HGR0545518.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            14958..15731
                     /locus_tag="ACL3G6_000965"
     CDS             14958..15731
                     /locus_tag="ACL3G6_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0545519.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            complement(16859..18364)
                     /gene="adcA"
                     /locus_tag="ACL3G6_000966"
     CDS             complement(16859..18364)
                     /gene="adcA"
                     /locus_tag="ACL3G6_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HGR0545520.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVTKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYVEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(18374..19180)
                     /locus_tag="ACL3G6_000967"
     CDS             complement(18374..19180)
                     /locus_tag="ACL3G6_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HGR0545521.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(19173..19877)
                     /locus_tag="ACL3G6_000968"
     CDS             complement(19173..19877)
                     /locus_tag="ACL3G6_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGR0545522.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVSHA"
     gene            complement(19877..20317)
                     /gene="adcR"
                     /locus_tag="ACL3G6_000969"
     CDS             complement(19877..20317)
                     /gene="adcR"
                     /locus_tag="ACL3G6_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HGR0545523.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELASRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(20472..21740)
                     /gene="dltD"
                     /locus_tag="ACL3G6_000970"
     CDS             complement(20472..21740)
                     /gene="dltD"
                     /locus_tag="ACL3G6_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HGR0545524.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(21733..21972)
                     /gene="dltC"
                     /locus_tag="ACL3G6_000971"
     CDS             complement(21733..21972)
                     /gene="dltC"
                     /locus_tag="ACL3G6_000971"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HGR0545525.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(21986..23230)
                     /gene="dltB"
                     /locus_tag="ACL3G6_000972"
     CDS             complement(21986..23230)
                     /gene="dltB"
                     /locus_tag="ACL3G6_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HGR0545526.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(23227..24777)
                     /gene="dltA"
                     /locus_tag="ACL3G6_000973"
     CDS             complement(23227..24777)
                     /gene="dltA"
                     /locus_tag="ACL3G6_000973"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HGR0545527.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKSDSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     ITDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDSVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(24798..24929)
                     /locus_tag="ACL3G6_000974"
     CDS             complement(24798..24929)
                     /locus_tag="ACL3G6_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HGR0545528.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(25160..25864)
                     /locus_tag="ACL3G6_000975"
     CDS             complement(25160..25864)
                     /locus_tag="ACL3G6_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGR0545529.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPISNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            complement(25934..27760)
                     /gene="glpO"
                     /locus_tag="ACL3G6_000976"
     CDS             complement(25934..27760)
                     /gene="glpO"
                     /locus_tag="ACL3G6_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HGR0545530.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKSDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTSAANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            complement(27802..29310)
                     /gene="glpK"
                     /locus_tag="ACL3G6_000977"
     CDS             complement(27802..29310)
                     /gene="glpK"
                     /locus_tag="ACL3G6_000977"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HGR0545531.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            complement(29469..30896)
                     /locus_tag="ACL3G6_000978"
     CDS             complement(29469..30896)
                     /locus_tag="ACL3G6_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0545532.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAAMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRNLFLDSAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLVAIRQLLFT"
     gene            31061..31933
                     /gene="hslO"
                     /locus_tag="ACL3G6_000979"
     CDS             31061..31933
                     /gene="hslO"
                     /locus_tag="ACL3G6_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HGR0545533.1"
                     /translation="MNKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            31920..32900
                     /gene="dusB"
                     /locus_tag="ACL3G6_000980"
     CDS             31920..32900
                     /gene="dusB"
                     /locus_tag="ACL3G6_000980"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HGR0545534.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(33130..>33330)
                     /locus_tag="ACL3G6_000981"
     CDS             complement(33130..>33330)
                     /locus_tag="ACL3G6_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
                     /protein_id="HGR0545535.1"
                     /translation="NANGSMATGWLKDGDTWYYLEASGAMKESQWFKVSDKWYYVNGS
                     GALAVNTTVGGYRVNANGKWVN"
BASE COUNT         9992 a         7366 c         5789 g        10183 t
ORIGIN      
        1 tgacgtggtt tgaagagatt ttcgaagagt attagtctat tatttcttct cagcgcgaag
       61 ggctgacaag atttgtgttc ggatatcatc cacaccattt ggagtatttg gtaaaaagat
      121 ggtttgattt cctttagagg caaaggtatt caaggtatcc aaatactggt tggtcaagag
      181 gatagacatg atttgttctt ctgtcatgcc aacattggct tccttgagtt cggtgataga
      241 ctctgccaat ccatccacaa tcgccttacg ttgttgggca atccccacac catgaaggcg
      301 gtctttttct gcttcggctt cagctgcagt gacaatttta atcttgtcag cttccgccaa
      361 ttcttgtgct gcgacccgct tacgttgcgc cgcattgatt tcattcatgg attgcttaac
      421 ttctgcatcc ggttcgacct tggtaatcaa ggttttcacg ataatgtagc cgtaagtggt
      481 catttcttct gctacttggt gttgaacctc aagggcaatc tcatcttttt tctcaaacaa
      541 ttcatccaag gttaattttg gaacagaaga gcgaagagca tcttcgatat aagatttaat
      601 ctgagattct ggacgtatga gtttatagta agcatctgtc acgctctgct cgttgacacg
      661 gtactgagtc gctacattca tcataacgaa cacattgtcc ttggtcttag tctcaaccac
      721 aatatcactt tgcaacaagc gcaactgaat ccgtgctgca atcgagtcaa tcccaaaagg
      781 caagcgaata tgaataccgc tattggcaac cttttggtat ttcccaaagc gttcaataat
      841 cgccaccgac tgctgacgaa ccacataaac tgtactcagt gtgactatca ccaataggag
      901 cacacaaaca atcagaaaaa tcatgaaaaa tattgccata atggaacctc cacaagtatt
      961 tttctagtat tatagcacat ttaaagaagg ctgtgccgtt tttactgcga tttttcctga
     1021 aatgtcaata attagaggtg aattgtccta ttgtcgtcca atctcttgct aaaataactc
     1081 tttataaaag gcaatcgttt cttctaaggt tggcataaat ggatttcctg gtgcgcaggc
     1141 atcaatcaag gcattcttag aaaggtattc aaagtcgaaa tctttttctt caataccaag
     1201 ttcagtcagt ttcttaggaa tacctactgt ctcagaaagc ttctcaatct cagcaatcgc
     1261 ataatcggca cattcttgat ctgatttacc ttctacatga agtcccaagg ctttggcaac
     1321 attgcggaaa gcttctggta cacgtttagc attttcacgt tctataactg gtagcaacat
     1381 ggcacagcac acgccatgtg gcaaattata tactgcaccg agttggtgag ccattgagtg
     1441 aacataacca agaccagcat tattaaagct cataccacca aggaagatgg cattgaccat
     1501 accttcacgc gcttcaatat catgtccatt ttctacagca cgaggaagat attccttgat
     1561 aagctcaata gcaccaatag acagtttctt ggttacatca taagcaccag gtgttaccaa
     1621 agcttcaaca gcgtgagtca gagcatccat accagtagca gcagtcaggc ctttaggttt
     1681 ggaaagcatg agttccgggt cattaacaga gataagagca aggctattct tgtcaaccat
     1741 taccatctta accttgcgtt cttcatcagt aatcacatag ttaatagtga tttctgcaga
     1801 agttcctgcc gttgtattga tagccacaac tggcaagcct tttttagcag acttatgaag
     1861 cccttcataa tcctgtggtt ttccaccatt tgtagccatg atagaaatac aactagctgc
     1921 atcctgtgga gaacccccgc caagactgat gataaagtca cagccatgtt cttgcaaagc
     1981 agctacccca tctgtgacat ttttacaagt agggtttggc tctacatcgc taaagatgac
     2041 atattcgatt ccttctgtat ccagtggttt taaagtctta ggtaaaatat cactgccttc
     2101 gatgtactta tctgtaacca aaagtgcctt tttatagcca agttccttga tataaggacc
     2161 cacttcattt acaacacctt ttccaataag gttgactgcc ggaacataaa atgtagccat
     2221 ataattttcc tcctgcgcct ccgcgctatc tatttaacat cattatatta ctttttgtat
     2281 tcgtttttaa ttatttgtga attgtttaac aaatcttttt aaaaggatag gagggacgta
     2341 agttcacctc ctatataaac aagttttatt tatgtagtgg tcccaacaac tgacatgcac
     2401 aatagtctgc tgattctaga tcttctgttc caaataagga ccaattttta ggtctaaaga
     2461 tatcttcctc aggtacatta tgcatattga caggaattct caacatagaa gccaaggtaa
     2521 tcaagtctgc tccaatgtgt ccatatgtta tggctccgtg attagctccc caattattca
     2581 tgacgtcata gacagacttg aaagcacctt ttcctgtcaa acgtggagca aaccaagtag
     2641 ttggccatcc tggatctgta cgattatcta aagtatggtg aacatcttca ggaagttcaa
     2701 gtgtataacc ttctgcaatt tgtagcactg gaccaacccc ttttagaaga ttgagacgta
     2761 ccattgttac tggcatatcc cccttcgtca agaaacgagt tgagaatcct cctccacgga
     2821 agtattcgcg gtttgctggt gggaagtctg tattttcaag catagcctgc acttcacttt
     2881 cttccaactc ccagaatggt ttcataacag gtttgccatc tcgagtagct tgacctgtac
     2941 catccaatgt acaagaacca gagttgatta gatgtaagaa gccagctgca gcacgaccct
     3001 ctaaagtatg tcccgttaca cgtttaacag cctctgggct ccaataagta cgcacatcag
     3061 caaagatttg tggagtattt gttaatagat aattaaagag catagacaca ccatttagtg
     3121 aatcattctc tgtcgcaaat acaaatggtt ttcgaatacc attccagtca aactgagtat
     3181 tgaggaaagt ttccataaaa tctccatttg gaaaatggtc tgtccactga cgttgacctt
     3241 ggaaaccagc tactaaagca tggtgaccaa ctgcttcttc ctcaaaacca agttcagcaa
     3301 gtcttgggtt accaaccatt aagtcacgtc caatcatgaa catcttaata acaaattccc
     3361 attgtctatc tttttcttca cggcttaaaa caaggtcttc acggttatgg tcgaatcctt
     3421 cttttacgtt ttctttcacc catttgagcg cacgttcgaa ctcttcaggg tcgtaaatac
     3481 tacggtccat acggcgcgtg aactccgtca tatctaccga ttcatttcgc attcctaggt
     3541 attcttggaa gaaatccgga tttacaatag aaccaccaat ccccatcgaa acactaccca
     3601 ttgataggta agcagtgtct ctcatcaagc cagttgcaag agctgcacgc gcatagcgta
     3661 aaagtttttc tttgacatct tctggaatat ctgtgtcact agcttcctga acatctcttc
     3721 cataaatccc aaaggctgga atcccttttt gagcatgtga agctagtaca gctgcaagat
     3781 agacagctcc tgggtgttct gtcccattaa atccccaaat agcatgagga atatctggag
     3841 acatatccat agtttcacta ccataacacc agcatggtgt aactgtaatt gttgcgcaaa
     3901 catttgattt tttaaacaac tcatgggaag ctgcagcctc tggtacacgg ccaatagtag
     3961 atggagaaat cacgcattcc acaggttccc catctggata tttcaatgtg cttgaaatca
     4021 aatctgccac acttttagcc atgttcattg tttgcacttc aagtgattcg cgtacacctt
     4081 gacgacgacc atcaatagtc ggacgaatcc caatacgtgg atgttgaatc atactatttt
     4141 cctcttattt ttctgtttct ttcatactac catctccatt atatttacgg tagcctgggt
     4201 gataattttt aaaattactt ataagtataa acctctacct ctgctaaact taaaggaatt
     4261 cctgcgcttc tcaaagaaat tctaaccttt tttcccttca gtccttttaa gtctatggat
     4321 agattattgc tttctaaact gtcaatatgt tgtgtaaaaa cttcataatc atttgaatca
     4381 tatataataa tatcaaaatt tgataatctc tgaatttcag catctgttct attataaata
     4441 attaactttt ctaattcttc ggtttgtgct aaatctatct cccaccatga aggagaatct
     4501 tctttggtat gagtcactga atgatgacca taatctccgt ttttatttcc atcaactgct
     4561 agacgagaaa aaccattgta atccgttgaa ctctgtcgag tttcttttgt taatgcaata
     4621 ttagaaagtt tcttcggagt tctctttgaa ccatagactt caacttccgc taaacttaac
     4681 ggaatagctg ctgattttaa ttctattttg actagcttag cccctacaga aggtactttt
     4741 aaagataaca aaccatcaac tactttatca aaatgtcttc taaaaacttc ttctcctgat
     4801 gaagatagaa aaataacatc aaaattagat aaacgctgag gttcggcatc tgttctatta
     4861 taaatatcaa ctttagaaac cgtaaactct tctcccagat cgacctgcca ccaagcgtta
     4921 gaatctgcct tagtatgagt caccgaatga tgtccgtaat ctccatcttt attaccatca
     4981 actgctaaag cagctacacc ctcataattg gttgaacttt gagtagctac cttatttgta
     5041 gagactactt tatcttctgt tattttatct atatcctctt cagattgctt accatctgat
     5101 tctctaaaaa cctctacttc tgctaaactc aaaggcactc cactcgttag taatttaact
     5161 ttaatatacc ttgctccttt ttctttgaaa tctagactaa cagattcacc cgacaaatta
     5221 ttaacatgtt tcttagcaac ttcgtttcta ttattgtcat atagaatcac atcaaaatta
     5281 gatagacgtt gagtctcagc atctgtgcga ttataaattt taacaagccc aactttatcc
     5341 atttttttca aatcgacttc ccaccaagag ggattatctg ccctagtgtg tgttaccgaa
     5401 ccagagttaa aattaccatt tctgttacca tccacagctc tattagggtc tccattgtaa
     5461 tctacagaac tttgtgttgt tggttttgca tatgctatat tcaaattacc atcattaaat
     5521 ttatctggtg ttgggaaaga gactggacct gtcccctcag tatttataga catctctacc
     5581 attccattat gattaaccgt aatggtataa acatgggtat tctcatccca attttctgta
     5641 taagtataat gatttttatc gccacttata tttatctgag gtttatgacc agtatgccct
     5701 tttaatgtaa gtgttgttgt cctaaagtca ttatctacag gattgatgga ataatttttg
     5761 cttatccagt tcgctaactc taattcttct ttcttccaac tttttgatgc atcaaaattt
     5821 cctgataatg cccacatagc tgtcttatct gtcctgtaat tattcaataa aatatgtaaa
     5881 ttatttggat tttctttaac aacagcgtaa gtatgtggcg tcaaatctaa cgataacgac
     5941 tttgtattat tagtatacat aggcaacatt acttgctgat ttttattgat attagcatta
     6001 ctattataaa tataccagga attacctaca cgctgagcat acccatctcc ttcataaagt
     6061 tttggataaa gcgagtttaa atagttgact ttactagaca attcctcact atttttagtc
     6121 aaaatttttg cattagggaa tatagatgaa atcttttcct tatcaatttt ctcatgtatt
     6181 acaggaagaa tatgatatct cccattatta tataaaggca ttgtttcatc attcgaataa
     6241 agtccttgat aaaatccgtt taatgaacta atcctacctt ctccattcca aaatacagct
     6301 tttgttctat ttacaacttc ttccttactt ggagctggat tttgtatagc atgtctaaag
     6361 aaaggaataa tacctttagt aaatgctgga gttggtacat catttgtcat aaatgtatac
     6421 gcggcacatt cgaaattata aactgtgcct cccccagtat atacattcat catttccata
     6481 gcaatcattg attctggttc cgatgcatag gatctcatat ccctagctct tccagtttca
     6541 aatgtgtttg tataatgttt ttcccaccat ttccatgtat ctgttgatga gccccagtta
     6601 tcacataagc cactcaacca aaatccacta acgatagaat ctgtacccgc atcatctctt
     6661 attggcgtat ttttagttgc caacaccaaa tttttatgat atttttgact cgcttcaaag
     6721 aatgtcggat cattcataat agtttcccag aaccattttt catgatcatg ccagataaaa
     6781 tgcgctccat atttggcaca aacttccaaa tatttagcac tatgcggagc taactggtta
     6841 ttgtaaatcc aataattctc aatatttaaa acacctttta acacactata cttttggaat
     6901 tgttcatcta accactctgg aggaactgta ttacgctctc cagccgacat aataaccaag
     6961 aaaactggaa tgtttagact ttgagcttcc tccaacatct tgacatacca ttctctcaat
     7021 tctttcgtat ctcgtggaat acaacttgtt ggtttacaga cttttgcagg atgaagttca
     7081 atcgctgcat atggctttac atcttcagga atagcttccc atgctccctt caatgtgttc
     7141 ccccaccata atccgttacc attatcattg ccatacaacg gagaaagcaa caatggcgat
     7201 tcattattaa tcgtcgttct catttgaaca cgattatcag ccttaactcc tgctaacaat
     7261 ccaaaacata acatcccaat acatacaaac aatattgtga ttaattttct ttttattttt
     7321 tctttattca tgacttatac ctaaaaattt aactcaataa ttttttctga attaaatacc
     7381 aattcaatat tttgtacatc agtatttttg ccatatattc ttactcttac tttttgatct
     7441 ttgtttcctc cttccaattt taggaatgtt atatccccat ttttccaagc aaacgatacc
     7501 ttatatcctc ctcttactct gaaacctttc acttctcctt ctgaccaagc agaaggtaaa
     7561 gctggaatta gtgataacca attatgatgg ctctgtacta ataattcaca aattccactc
     7621 accaaaccta aattaccatc aatttgaaat ggtggatggt caagaaataa attgccaaga
     7681 gtcgcattat ttaacaaacc attaatctgg ttataagcag gttcaccttg atatagtctc
     7741 gcaaaaaaat gaatcagcca tgcagcactc caacctgttt gtgtactagc atgcaaacca
     7801 cttactaacc aattattaat cgcttgctcc ctctcctgtg aagataaaaa attagcgttt
     7861 gataatctcc tattgatagt gattttagct gcttctgcta attccggagt tttatgaata
     7921 tcaatctcat tataaggata aagcccaaat agaggtgaaa tgtgtctatg cccaggctct
     7981 acttcttcat aatcttctaa ccattcttgg atttgcccat tactacctat ttttgtttta
     8041 ggtagtttct tttttaactc cttcacacga ctaataaaat ccgaattgtc tcctaattgt
     8101 tttgcaatgc caatgcatga atcacaaaaa tatcttagaa tttgattatc aattgtagat
     8161 gatagacaag catttccttc aataccattt tttaagcgat atttattttc cggtgagaca
     8221 cttggacctg tcatcaagta gccatccacc tcaaataaat aatcttcaaa gaaaagaaat
     8281 gcttctttta tcatttcaaa atgttccgta agaatacgct catcttggaa atataaatag
     8341 tgttcccaaa tatgagtaca taaccatgga atagttaata cccaaattgc agcccccatg
     8401 gcatgagatt ggggagccgt atcgccaaaa ccatccgtat tatgatgtgc tgtaaaacct
     8461 ctagctccat acattttctt agcggttagt cttcccggtt ctctcattct ttcgagcata
     8521 tcaaataatg gatattctac ttctggtaaa tcacatggac ctaccatcca ataattcatt
     8581 tgagtattaa tattaatcgt atatttagaa ccccaaattg gatttaattc atcacaccat
     8641 attccttgaa gattggcagg taaaccattc ggttgactag acgatattaa cagatatctt
     8701 ccataatgaa ataacaagtt agtcaagtag ttactatact ttttagtgtt ttcaagaagt
     8761 agattcgttg gaatgctaag acaatcttta ctatagtcta gtttaaaatc aactctatta
     8821 aattgctcct gatatttttt tacatgttca tctttttctg taaagtaatc aatactacta
     8881 aattctccct gaagagaaga aatatctata tttccccaat aatccgtcat tgatttgaga
     8941 taaagaaata cctctgtagc attccgaata actattgtct ctcccaatac acttacttca
     9001 ccatccgtaa ccttagaatg acatactact ttaaactgaa caccttttct acctccagca
     9061 gaggccgaca ttaaaattgt acttgaatcc agtttagata cttcgtcatt aaaccgttta
     9121 tttctaccca aattaatgtt taaatttaat gtgttttgaa ctgatgacac tatacggcaa
     9181 cataaaatat tcttattaaa actcgtaaaa tattctcttt ttatttgtaa attacaacta
     9241 ttaggctcaa acacaacatt agaaatagct gtatctaaat ctagctctct ttcatacaat
     9301 gaaagagcac aagactgaat atctatatgc tcaatgtaaa gttccccaag taattcatag
     9361 tggctttgat ctcttggggt agcaaacatt gttaacttta tcaattcttc ggctttctga
     9421 atttctccat ctaaaagata ttcccgaatt tttttaagat gcaatagtga gtctggatta
     9481 tttctatctg actttcctct ataccaaata gtctcatcgt ttagttgaat acattctttt
     9541 gtagctgaac cataaatcat accacctaaa tgaccgttcc caatcggcaa ggcttcattc
     9601 caatttgagg cagctttctt ataccataat ttcactcttt acctctcttc caaaatggag
     9661 gtgatatccc aaataccacc tccacacttt ctactacttc aaaattccta aaacaactag
     9721 gataactcca atagccataa cactaaagat tagtacaacc ggattctttc cttttctaat
     9781 taatttacac attaataaag tcaaagccat agggataaat cctggaatta attttgtaat
     9841 catttcttga acagaaataa caagttcccc ctgcttaaat tctaatccaa aattaatacc
     9901 aaccattgat ggaatcaaac cacccactag tactagccct aatgctgtcg ccatactcgt
     9961 aacgcgattc aatgttcctt ttgtattatt ttcttggata agactagaac ccttagtata
    10021 cccatatttc aaaccgaaat atttaacagg aatattaata atattaaaca atattaaggc
    10081 gataaagata cctaaagcac cgccgtcttt agaataagac gcaccaatac taaaacagat
    10141 aggaactagt gtcagccaga acaaactatc tcctagacca gccagtggcc ccatcaagcc
    10201 aactttaata ccagtaattg aagctgcacc ttcatttcct tcttgttctt ccatagcgga
    10261 agtaactcca agaataaatg gtgccgctgt ttgatgagta ttgaaaaact caaggtgacg
    10321 tttcattgca ggagaagctg aatctttgtc tgggtatagt tttttcaata ctggaagaat
    10381 tgtatataga aaacctaggt tctgcattct ctcatagttc catgaagaac catacataaa
    10441 acttcgtttg aaaacttttt taagttcaac tttagttact ttattattca tcatagatca
    10501 agatcctcct caacatcact acttgaagtt gtttcttgtg gtttacttcc aatcatatcg
    10561 tagaagtatg ctaccgcaat accaactagt gagatcccaa tggttgacat tcctccatac
    10621 acagaacaaa tgaatccaat caacaagaat acccacatat ttttcttgag catcatattt
    10681 aaaagcatac caaaaccaat tgaaggtagt aaagcacctg cagagttaag tccctgcata
    10741 acgattggtg gaaccttagc aaacaagtct gccacatatt cccctccaag cataatagct
    10801 aggaaaattg gtacaatttt aaataacgtg attaaaacca aacttgaata atgataaaaa
    10861 ccgatctttg aataatctcc gtttttagca tcattatcag cttttttcac aaaataaaca
    10921 tctaaagttt ttgcaagaac atccaactgt tgggtagcaa ctgcaattgg aactgctata
    10981 gcgataccag cagtttctcc ttgaccagat aaaataccaa atgcagtacc aataatcgca
    11041 cctgaaatag tatctggtgg agtgtaacct ccaatacctg ttacaccgag ccaagttaat
    11101 tcaagagctg aaccaataag aacaccttgg gtgaaatctc ctaagactaa gccaaccatt
    11161 gcacttgtaa ctaacggacg gtgaatcata aataacggtc cattatagtc aatagtggca
    11221 ataatcccaa ctaatgtcac cagtaatgct tgtgtgaata gcatatactg tacctcctta
    11281 aattattttt ataaaaattt ttccaacatt gtaactttat cattaggaac catttgaatt
    11341 tcaactctcg ttcccttatc aactattttc ttaaaataat atttgtcttc ttcacctaga
    11401 gctacacctc ccgttacctt ttcattttcc tccgttttac tcatctgtcc tacattgagg
    11461 tactccaatt ttaaatttcc ttcaatagaa tcatacacat cttttggatt tgtatatatc
    11521 agcattgttc tcttttttat tggcacagag tttaaaactt ccacaaaccg ttttacacta
    11581 aagaaaacaa tttttaaacc taccggtgca gaaatcttta aaatagattg tcgtgtttta
    11641 tcttctgaga tgcgatcatt aacaatgata acttgctcaa tatcatactt ttttagccac
    11701 gtagtgacaa cttgaccatg taccagacgg tcatcaatac gaacaaactc tatagacata
    11761 aatcctcttc ctcctctacg ttaagttgtt gtttaacatt aaacaaacta ttttgagcat
    11821 tttgaacaat ttcttctaaa ttgatttttg aatcataact tgatattaat tccactagga
    11881 gagggatatt aaaccctgtt acaatatcaa ctgaatccaa atttaaaaac cgtgacaaag
    11941 ccacattatt aggacttcct ccaatcaagt cagtcaaaac gataacctct tgatttgagt
    12001 ctaacagttc atccacttga tttttaaaat aatgttcaaa ctctacaata ttctctccag
    12061 gcatcaaacc taatgtccta actctatcat ttgttgtctc accaacaaac atttctgcgg
    12121 tcatgagagc tccgctagca aaattaccat gactggcaac taaaattcct ctattaaaca
    12181 ttttctcttt caacaactac tcctttctta aggataatat tagcataaag tgaagtttct
    12241 cctgtagcaa caatagcata agctttctta ctacgttcat aaaagtcttc tcttctaaga
    12301 taagtaatcg ttttaagatc tgtaccatga ccttcaatca tctgtctata ggtaccccat
    12361 atcttaggaa tatcatcacc cgaaacaacg ttcataaact gaattgaact atcgacgtaa
    12421 ctatctaatg gcattaaata cagaatggaa tctaataatt ctggaatatt tacgccatca
    12481 caacgaatta gcttatttgc acatgaggca gaaggataat tcgcgtcagc taatactatt
    12541 tcatctccat gtcccatttc cattaaagtc ttcaataaat ctggagaaat atttttcggt
    12601 atatgtttta acattaatat cctccctatt ttctctgacc gtatgtttta aatttttctg
    12661 ccattaaatc catctcctca tcaggaagaa ctactggctc tccaaaattc ttagctaaac
    12721 aataaatttt tgcacaatat tcaacttctt caacaatatt aaatgcattc aataaatttt
    12781 gtgcacctgc taaaattcca tgattcgcta gtaaaactgc tctacgacct tccattgctt
    12841 tagctgcatt cacagccaat tctttcgtac catatgttgc atactcagct acccgaacat
    12901 ctttccctgc cactgcaatc atataatgac tagccggaag tggttctctg agacaagcta
    12961 atactgttgc ataagttgta tgagcatgga taattgcatc gatatcatca cgagtttgat
    13021 attgaatcaa atgcatatac cattcgctag atggcaagcg ttctccctct acaacatttc
    13081 cattaatatc catcactaca atatcggatt ctttgatttc aaagaaatca atacccgacg
    13141 gggtaattgc catcaattgt ttttcacgat cgaaaacact gagattccca cctgttcctt
    13201 tcgtcaaatc tgtttctact agcttcttgc catacttaat taattcttgt tttacatctg
    13261 acattcttgt cctcctcata tcaaaacact aaatattttt caattcacca attatccccc
    13321 cttcttgtac aaaacttaag aagggggagg gaggcaaatt tacaaactct caatcttttt
    13381 aattcttttg ggagtaataa ctctctaatt gtagaaactc ctcaataaca tggtgagctt
    13441 cttccatccc ttttaattgt cccatagcta tgagctgcac aacaatattc cccacagctg
    13501 taccctcagt cgaacctgta agaacctctt taccagttct atcagcaatc atttggttaa
    13561 agtaactggc tctagcacct cctccaatca catatatcct cttataaacc ttatgagtta
    13621 gttcttctag taactctatc gctttcctat acgtttcagc taggctttca taaacaatct
    13681 taaatagttg tccatctgtc cactctctag tttcatgatg ataagctaga tattctgtca
    13741 aagtcttgtg catatcagat tctgttgcaa attcagttga ttcagtatca atcagaggaa
    13801 gattttcttt ttctttctcc accattgtcc taatatcatc aaaagaatag gctttccctc
    13861 ttcgttcaaa tgaacgtctt agttcctcta tgatccacaa ccctgtacaa ttcttcagaa
    13921 atgtaatcac tccatcttta ccgacttcat ttgtaaatcc ataactgaag gattcggtag
    13981 taagaatcgg tgaagtaagt tccactccaa ccaaagacca agtacctgat gaaataaata
    14041 aactaccttc tgtcttaggt actgagacaa tcgcacttgc tgtatcatga ctacaaacat
    14101 tcacaacagg aatatcgcct aaaccatact ccttttttat ccttccaaga acatttccct
    14161 ctgaaacaat ttcaggaagt aaagatgaat ccaattcaaa tagttttaag atattctgat
    14221 tccaattttg actcctagga tcaaataatt gagttgttga agcaatgctt ttttctgtag
    14281 caaacttacc tgtcaagaga taattaaaca aatctggcat taaaagaatc ttattggtct
    14341 tatagaaaga gtcaggagat tcttgacgtg ccttaaagag ttgaaacaag gtatttatct
    14401 ccataatctg atttcctgtc tctgaataca gtttttctaa ttcagtcatt tcagatattt
    14461 cctttaacac tccctttgtt ctttcatcac gataatgaac aggttgtgat aacagcttac
    14521 cttcattatc aatcagtcca aaatcaactc cccatgtgtc aataccgata gataaaatct
    14581 tgtaactagt attagccaag cggatacttt caagaatttt agctagtaga aagtcaatat
    14641 cccaagataa atgccctttt actctaatag gtagattaga aaagcgattt atttcttcca
    14701 ttactagttt attttcagaa aggtaaccaa cgattgctct tccagaagtc gcacctaaat
    14761 ctattgctaa aaccgcttcc atttttcttc tctcttcgtc cttgattaag tttattataa
    14821 tccccacatt ttattttttc aatatgtgaa cgcttacttg gataatgttc aaatgttaac
    14881 ccaatattca taaaaataat tcaaattcct ccaatttgtg ctataatata gttgaaatga
    14941 taaattagga ggagcttatg ataaaagatg aacgtgtact tgaattgatt gaaattatta
    15001 aaaagaaaaa aagaattgcc gtaaaagagc tggcagaaat cactttctcc agcacaagta
    15061 ccttacgtcg tgatttaatt ttcttagaaa atcaaggtct tatcaaaaga aagcacggat
    15121 acgtgaccct gtcctctatg aacacaattg aactttctca tcaaatacgg gaaggagaaa
    15181 gtactaggca aaaaagacta atcgctagtc tcgctaaaga ctttattcgg tcaggtatgt
    15241 gtgtttatct ggattccagt acgactgtct acgaactttg tccctatctt tctgaacttg
    15301 ataatttgat tatttttaca aatggtttac atactgcaca aaccctatct gaaactgtta
    15361 aagatagctc caaaatcttt atcacatctg gcgaggtcaa acatcaatcc tgttccgtgg
    15421 tcaattacga taaggaaaat tctttattag atcattttaa tatcgattta gcattttgtt
    15481 cagcaagagg tattgatgac caatatgttt atgaagcttc tctcagccaa gctatttcaa
    15541 aaaagaatat tattgacaaa gcccatgaaa ccatcttact gattgatagc tctaaatttt
    15601 acaagactgg attttttaaa attaatcccc tatccaaata cacaaccttt atttctgaca
    15661 ccgtgccaga tcaaaaatta ttagacgcag tcgaattatt tgatggagaa tgggtttctg
    15721 atattcaatg aaaatcaaat aggaagctag tctcagcttg ctcaaagtac agatttgaaa
    15781 actgatgaag tcaagtcccc catggacacg gcaagacgaa gctgacatga tgtgaagaga
    15841 ttttcgaaga atactcgttc tgtctgctga ctgatttaca aatattcacc acatgacatt
    15901 attttcttag caaccctaaa aacagaggct ggacaaaaac tcaatttcaa gagaaatggg
    15961 gcaaatattc ccacaataaa acgcatagta tcaagttttt gcacacctga tattatgcgt
    16021 ttttctgatt ttaaagactt tgtcgcctag accctatatt tcaagaatta agtgaccttg
    16081 atgatctaaa tgtattgtgg tatactattt ttgtcatcgg ttaccgatta cgttcctatg
    16141 ggttcgtgag aggaggtgaa actaatgagc cttatcatag agctcgctct tactattata
    16201 gcggatgtta tagctggaat tatcttgtat ttcatctgca gatggctaga tagtaaggag
    16261 tagaccgaat gactagccta taaacacccg ttaaatctct aagatacgtc aaaaaagccc
    16321 ttaactacgg ccatagttag gggctttggt gttctaatga accttatcaa ttaactacat
    16381 tttagcatat aatctacaat agttcaagca ttaagtgagg ttgatgatct aaatttagtg
    16441 tggtatacta tttttgtcat cggttaccga ttacgttcct atgggttcgt gagaggaggt
    16501 gaaactaatg agccttatac cagagcttgc tcttactatt atagcagatg ttatagctgg
    16561 aattatcttg tatttcgtct gcaaatggct agatggtaag aagtagaccg actgactagc
    16621 ctataaacac ccgttaaatc actaagatac gtcaaaaaag cccttaacta tggcactagt
    16681 taggggcttt ggtgttctaa tgaaccttat acactaacta cattctagca tataagtcct
    16741 aatatttcaa gagttttatt tattttttca ggttccctta gttctgaaag gtctataatg
    16801 aagttagcca tctagtatca aaaaaccgac tagctcttat gaactagtcg atttctcatc
    16861 aatgcgccaa catttcttgg gcgatttctt ggccagatag gttatctggg tagtaggttg
    16921 gccagttgtc catttcttca aagagggctt cttggcttgt gcctccaaag aagatatgga
    16981 aatgttctgc cttaactggg gcgatattgt ggtcactaaa ctgaacatac ttgaattgtc
    17041 cagcgtcagc atctgtggct tcaaagagga aacgcacgcc acgattgcct ttcttgtaag
    17101 tcaaaatttt cttaccgaca tacttgtaag tgtatttctt gctttgtcca ccttgaacaa
    17161 attccatagt attatcagta atgttaatct tagtcacatc tgtctgatag ccttttgtat
    17221 agtaagcctt gtactcagcc tgggtcatct taccagtcaa cttagccttg tagtcaaaga
    17281 cttggtcaaa cgtgccgtct tcaaggaaag gataaactga ttgccagtta cctgcatagt
    17341 cactcaaggt gcggtccttg acagctgcat cctcgaagta accattttgg actgtcttgg
    17401 tatcctctgc cttttcaggc tcgattgctg ggccttcttg gtctgttgtt tgtttcaaag
    17461 ccttgaggtt tttctccatg atagagatgt aattttctcc agccttggtg tcctcttctg
    17521 tcagactttc taaaggattg aggacatcag ttttgacacc tgcttctttt gaaagtgtgt
    17581 tagcaagggc ttgtgaggca ttttcttcaa aatagatata ggcgatttta tttttcttga
    17641 catactctgt caattctgcc aagcgagcag ctgatggctc tgcatctgga gaaagtcctg
    17701 agattgcgac ttgtttgagt ccatagtcca aggcaagata gttaaaggct gcgtgttgag
    17761 tcacaaagct cttttgtttt gcttgagaca agccttctac gtaagcctta tccaaggctt
    17821 gcaatttttc gatataggca gctgcattct tctcaaaggt ctctttttta tcaggataat
    17881 ctgctgacaa gctgtcgcgg atgtgctcta ctagtttaat ggcacgaact ggtgataacc
    17941 aaacatgggg gtcaaactca tggtgatgac cttcttctcc atggtcatgg tccccctctt
    18001 cttcctcgcc acctggcaag agcaacatat cgcctgtcgc cttgatggtt ttcacttttt
    18061 tcttatccaa ggtatctagc aatttaggta cccatgtttc catgttttca ttttcataaa
    18121 cgaaggtatc tgcatcttgg attttggtaa ctgccttggc agatggttcg tattcatgag
    18181 gttctgtccc agcaccgatt aggagttcta cattagccgt atctcctgcg acttgcttgg
    18241 taaattcata gacagggtaa aaggttgtca cgatattgag tttaccatct gcctgttttt
    18301 gattggaaca agccactaaa aacaaggcac atagactggc tagtaataag ctaatttttt
    18361 tcacgttcgt ctcctatttg ataaaacgtc ttactaaact gattagtata aagacagtta
    18421 caaaaataat ggtaatactt gcacttgcag gtgtttctgc atagtaggaa atgtaaagtc
    18481 ctgctaccat tcccaaaaag ccaatcgcac tggcaagcag cataaccgat ttaaagtttt
    18541 tccccagacg cagggcaata ctagctggca agaccataat ggtcgatacc agaagagctc
    18601 ctgctgcagg aatcataagg gcaatagcca cccctgtcac catgttaaaa agaatggaca
    18661 tggtacgaac tggcaagcca tccacaaagg ccgtatcttc atcaaaagtt aagatataca
    18721 taggacgaag aaagagaaag gtcaaaatca aaacaaccgc cgcaatgaca aagagggaaa
    18781 tgacctgttc ttcactgata gtcacgatcg aaccaaagag atattggtcc aaactcattg
    18841 aactcgagct tttacccttg ctcatgacaa tcagagaaac agccagacct gttgacatga
    18901 ggatagctgt cccgatttcc ataaagctct tgtaaaccgt acggagatac tccagaaaga
    18961 ccgccgcaat caagacaatg gcaatagtag aaacagttgg agaaatcccc aaaaccagac
    19021 caaaggctac acctgaaagt gagacgtggc taagggtatc actcatcaaa ctctgacgac
    19081 gcaagatgag gaaggttccc aataccggtg agaaaagact catagcaata accgccaaaa
    19141 aggcgcgttg tataaagtcg taagataata aactaagcat ggctcacctc ctggccattc
    19201 tcatgaacgt tgaaacaacg ccatggcgag tcttggttac ggactagatg aatattgcga
    19261 tccgcataat ccttaacttc ttcagggtca tgggtaatca tcaaaacagc cttgccatga
    19321 tgatgggcgc tgtggtgcat gagttcgtaa aattcatttt tacttcctgc atccatcccc
    19381 gttgtcggct cgtctaggat aaacacatca gggtcagaag caaacatacg cgcaattacc
    19441 gctcgctgct tttgtccccc agatagagac cccaagcgtt tgtctcgatg ttcccacatg
    19501 ccaactgagt ccagactggc cttgatatgc tcctcatcat gagcattcaa acgacggaac
    19561 cagccttttc tcggatagcg acccgacttg acaaattcat agaccgtact tggaaaacca
    19621 gcattaaaac tggcaatttg ttgaggaaga taggctattc tcaatttctt accttgcgta
    19681 tttgtctttg aaatagccac ctttccaatg cgtggttgca gaattccaag actggccttg
    19741 atgagcgtcg tcttagccgc tccattttcc ccagtcaagg taacaaattc cccactatca
    19801 acactataat tgatatgttc aagaacaggc tccttatcat aatagaagga caaatcctct
    19861 accgtaatat atctcattat ttgatttctc ctactaaagc agtcaaaaac cgctgaatca
    19921 ctttttgttc atttggagta aactgagtcg ccacttgttc ataggttaaa agtgtatgct
    19981 catggtgatg gtggtgctcc tcagcgattg gacgagccaa gtcagtcaac tgataaaaaa
    20041 tcacacgcgc atctttagaa tctttagatg tttccaacat cccttccttg accaaagact
    20101 taatggcctt ggtaactgcc gcctgactga cattgagacg actggccaat tctgaatttg
    20161 ttaaagattc ctctgacaag agcataagga tatgctcctg agtattggtc agggccacct
    20221 cgctagtgca atgacctatt aggatttcat gctgattttc cgcctgcaaa atcacctcat
    20281 tcaaaaaagc attgatatcc tttgctagct gtctcatatc tgactccttt ccttttagac
    20341 ttctcttttt taagagaaaa atactattct ttgacatttt gtttaccagt taattatatc
    20401 acaagcaaaa aaagagtcaa gaaaaaacgt gaaaactagt ttcattcttg aactcttcta
    20461 tattatatta tctattgaaa ttctttgaca tctccatcat aagtcgccca atctttgctg
    20521 aaaaagcgct cattcagatg gtaagtcgga gctggtgtgg gattggatag gaaaggatca
    20581 actgccttgt caaaagccaa ccaacccaac caaccaaggt gaatggtgtc cttcataaag
    20641 aaaggctccc caccgtcctt agaaaaatct gctatattgg taaaaccttg actttctaac
    20701 tggtagcgaa tcttctgcac cgtttgttgg tacatatcct ctcgtagacc agcatagtcc
    20761 atccattttt tattaacagg tggaatgata aaaatcgggt ttaccttaga tttagaaaac
    20821 tgtgttaaaa ccaactgcaa gtcattatac tctggcgact tgagataggt aaagcttttc
    20881 tgagaatcct ttaatttctt caaatccttc ttgatctgct cattatagaa ataattttcc
    20941 attcccatct cattattgga agtatttttt tcagcatctg ctttgacaac atcttctatt
    21001 gcttgataag aaaactggtc tggcaagatt tttaaatact tagctacatg cttatcgtag
    21061 ttaacatagc ctctaaccga aaactgacca aaaaaggagg cttggcgttc attaaaacga
    21121 gccaataatt caatcatttc attgtctgct gtcgacaatt ctcctttact tgccaacttc
    21181 tgaaccaggt ccttcatagc tacgtttggg aactgttgca gtaagcgagt cgctgcatat
    21241 tgactagcct gatccccaga ttgatgtttc agaaaactag tcaactggtc tccattaaaa
    21301 tactgctgga aggctgctgg atcatagcca tttttactga accactgagg tgagataaca
    21361 tacacaactt gtttattctc cagctgtggt aacatctgtt gcattccaaa atattggtta
    21421 agcgatgcag ctcccccctg tcctaaaaga taaggacggt aggaacgatt gtatttctca
    21481 gctaataccg caggatgagc accgtcaaaa cgaagccatt cactagagcc aaagaaggga
    21541 acaaaacgca catttggatc agatagtgct ctgacttttt gacttcgctc cttaaaacta
    21601 tcgatagtag tagccactgc tgaacgcttt tcagctccta gattatgatg catctcagta
    21661 ggataaaaga aaatgagcag aaaaaccaac aaaccagcga tcaagaccgg tccgaagatc
    21721 atccataagc gtttaagcat tttgtagctc cacaatacca gctatgattt tattagctgt
    21781 attccagtcg tcacgaccaa actctgttac agggacacga atgtcaaaac ggttctcaat
    21841 ctccacaatc aactcaaccg ttcccatact atccaagaca cctgcatcaa aaagatcttc
    21901 atccatcatg tcagaaacat cttccataaa caactcatca ataatttcaa taacttctga
    21961 tttgatatcc atattttatt tccttttatt ttttaaacca tagattattc aagaatccag
    22021 aaaagattaa gaatgacaac atgacaacat ggaaagtgac aaccatgcca agcaactgaa
    22081 tccagcgatt ctcaggtagg gcagccttcc ctgctttttt ccgttcctta ttgagcgttt
    22141 ttttcttgcg aacccaggca tcattgatga ccaagcctag tccatgaaag agtccatagg
    22201 cgatatagta ccaggtcaca ccatgccaaa atcccataat cagcatattt acaatgtagg
    22261 ccatgcttga ggttacatta cgatttttaa agactttctt tctggttaac accatcacca
    22321 ttcgcataaa gacaaagtca cggaaccaga aggacagact catatgccag cgattccaaa
    22381 actcctttaa atcccttgat aaaaagggct tgttaaagtt gatagggcta cggattccca
    22441 tcaagtttga gatggccaaa gcaaacatag aataacctgc aaagtcaaag aagagctcca
    22501 gaccaaaagt atacataact gccaaggcat agagattaaa gaagccacct gactgcaagg
    22561 ctaaattctt cagaggaggt agtaaggtct ctcctaaaac atgagctagg ataaacttat
    22621 acaaaaagcc ccacatgata tagcggacag attcatccag catatccatc aactcatctc
    22681 gctcaggaat agcctgataa ttttcattaa atcgcttaaa gcgatcgatt ggaccactcg
    22741 agaaagttgg catgaagaga aggaaacgga ggaattccca gagggtaaaa tccttaatca
    22801 ctccatctct cagctcgatg ataatcccaa ccgaacgaaa ggtcaggtaa gaaattccca
    22861 agaacccaag caaagactgc gttccattga tagctggttg caccttgaca aagataatcg
    22921 gaagtaggga cagaaaacta actaagtaga agacccactt gccatccttg ctttttcgat
    22981 aatgcttgta gaaaagcagg agcaatattt cccagcaaag gtaaataccc aaggcagcta
    23041 gttgattggt ctttccaccc accaacatgg tgacaataaa gaagagactt accaacactt
    23101 cataccaggc aaagcgtttc ttgaaaaaga ggcctataaa gatgggcaag gttgcagcaa
    23161 tcacataaac aaaatactga ggattgccat atggctctaa atgaggaagc tgttgaaaaa
    23221 actccatcat ctcttattca cctcgttaat caatcctttg atgtcaatct ttccatttgg
    23281 agtcagtggc aaactgtctc ggtaaaggaa tttagatggc atcatgtagg acatcatgat
    23341 gtctgtcagg tcttccttga tggccttggt aatatcgata tctcgctcaa actgctcacg
    23401 aacactgtct tttaagatga cataagccaa tagattttgt accttgtggt ccttgttata
    23461 gcgcggtact gcgacagcag attcgataaa gcgagacttg ttgaggtttt gagagacatc
    23521 ttctaactca atgcggtaac cgttgaactt aatctggaag tccatgcgtc cgccgtagag
    23581 aagcaagccc tcatctgtta tggttcccac atcgcctgtg tgataggctg gcagaccttc
    23641 aaactcaaag aaggcttctg ctgttttttc aggattgttc atataacctt ttgaaacagc
    23701 tggcccagaa acaatgattt ctccctgttc gccatttggc agtttatttc cttcctcgtc
    23761 aatgataaag gttggagaat cagccttggt atagccgatt ggtaggcgtt tgagagtcgc
    23821 taacatctcg tctgtcacgg caactgctga cagagctact gtcgcttctg ttgggccgta
    23881 agcattgatg atacgggcat ttgggaaacg ctcgcgcagt ttttgagctg ttttgaccgt
    23941 caattcttca ccatcaaagt agaaatgcgt gattccaggc attttttcac tgttgaagta
    24001 ttcagacaac atggccatat ctgcaaagga tggtgttgat gtccagatag cgattggcaa
    24061 tgaaaagata gccgcaaaga gttgcttaaa gtcctgagtg atgactgaag gaagagtgaa
    24121 aagcgtacca ccaagtgcca aggtcggtgc ccaatacatg acagacaagt caaaagaata
    24181 aggtggctgt gccagcattt gcggacgact cggtgtcgca aattccttat ccgtaatcat
    24241 ccagtttgta aagctgagga gattatcatg tgaaatctgc actcccttag gcttaccagt
    24301 cgtaccagaa gtaaagataa tgtagtaatt atcatctccc ttgactggat gcgtgatttc
    24361 atagttgttc ccttgggcaa aggcttcttg aacctgagct agatttatca ttggtgtaga
    24421 aacctgctcc aagggaaagg ctgaaatggc aataatcaag cttggctctg ctacttctaa
    24481 aatagctgaa actcgctcca aggccgaatg gctatcaatt ggaatgtagg catgacctga
    24541 cttagtcagc gctacaaagg ttgccaacat ttcatattct tggccaccaa aaacaaccac
    24601 aggagacttc tcaggcaagc ctagttggtc aatgactgca gccaaactat ccgaatcaga
    24661 ctttaaatcg ccataagtgt gttcctgccc caaaacatta tagacaggat agctaggctg
    24721 tgtctgagca aaatgctcaa tggtttcaat catatctgct attggtttat ttgacacaat
    24781 agggattctc cttcaagtta aaattcatta tagataaagc ttccttgacc ctgaccaaga
    24841 tagctaaaga agtaaagcag ccctagaaag ataagaaaat acaaggctgt ccgaccaaga
    24901 aagaggtaca attcttttct ctgtttcatc aagaaaaacc attcatttct gtaatttttc
    24961 gctaaaataa gagtgattct tactagctta tttttctacc attgtaccac tttatatagt
    25021 atcttttcaa ttgtttaccg tatgtttcca atagatttca gcttatttta aggattatgc
    25081 ggtttttcta tatctatttc aaaagaaaaa agcctgagat tttcatctca agctctagca
    25141 ataatagtta ttttctaaac taaaaaagtg agaatacaag cacggccaag gctgcaccga
    25201 taacaggtcc cacaacagga atccaagcat aagaccagtc tccgtctccc ttgtttgaaa
    25261 ttggaaggat actgtgcatg atacgaggtc caaggtcacg cgcaggattc aaggcataac
    25321 ctgttgtccc acctagcgat agaccgatac cgacaatcaa ggtacccact gcaaaggttc
    25381 cgatacctgc ctgaaaatcg taaagaccca aagcaaagat tgtcaacacc aaaacaaagg
    25441 ttccaaggat ttcgctaatc aagtttgata cagtatcctt gatggctggt ccagtactga
    25501 aggttgccag gatattgcct gcattttctt ctgcctcata gtgaggtttg aattgcaacc
    25561 aaaccaaaat ctgacccagc atagcccctg cgaactgggc taagatataa ggcaaaacgg
    25621 aagcccaagg caagtcacct tttaaagcta caccaattgt cacagctgga tttaaatgag
    25681 ctggactgag cttgccagat acaaatactg caaccgcaac tgcaatcccc caacccatag
    25741 taatcacaat ccaacctgag ctattgctct tggttttagg aagaaccaca cctgcaacaa
    25801 caccatttcc tagaagaatc aggattaaag tccctagaaa ttctccaaat aattcattca
    25861 tcatctttct gtctccatta aaaagaaggg acgagcgaca aggaatgctg ccctccacct
    25921 cttttatttt ttcttaattt tttaattctg ctaaatcgtt gttagcgaga gctgcttcga
    25981 catcagcacg gtaagttgct ttttcttctt ctgtccagtc atagaatcgt cccatttcat
    26041 ccaaaactgg ctcaacgatg ctatccaagc tatcacgcat aaagagcata tggttggtac
    26101 gacgaagaag gaagtcaact gggctaagag ccaactcgtt gcgcattgca tagtgaaggg
    26161 acaaagtatc tgccaagctg agtcctggcg cttgttccaa gctgtgagca agtgcaaaga
    26221 ctttcggtgc atttgaaccg taaagatttg ccagatagtg agcttccttg ctatccaaac
    26281 cacgtgatac tccaagttgc gcaaaggctt cgatttctga atccacattt gctgggttca
    26341 attctccacc tgaaacaggg taagttttag aattgatcaa tttaaagcta cggtcaaatt
    26401 ctgctttgag gatgtcaacc acgcgctcca tagctccttc agccatctta cggtagtctg
    26461 tgattttacc gccagcaaga gtcaaaagac cattgtcatc acggtccaag ctagacccac
    26521 gagaaactgc agatggatcc aaatatttct cagatgtgct actttcaagc ttgctgacag
    26581 cagactcaac atcttcacgt gttttttctt tggagagata agattcaaca gtcgcaatca
    26641 agttgtcaaa gctttcatca ctgatggtac cgttatttcc accattatag tcagaggcac
    26701 tgttccctgc aatcaatgga cgaagacctg cccagctgct ttcgatatca tcaatggtga
    26761 tgttggattc tggaaagcgg ttgttgacaa tgccaagtag ataatctaca tcttcttgag
    26821 ttacttttgg atgctccaaa tcacctgtgt agtctgtatc agttgtacca aagtaagtct
    26881 tgttttcacg tgggagaaca aagaccatac gaccgtcacc caaacctgtg tcgaagtaaa
    26941 ctggctgtga aaccttgatt ttgcttgaat ccactaccaa gtgaactccc ttagttgggc
    27001 gcatttgtga gaattgcgtt cccttattag acaaattacg tactttatca ctccaaggac
    27061 ctgttgtatt aataaccaga cgggccttga tttcaaatac ttggtctgtc aagagatcac
    27121 gagctacaac acctgtaatc ttgccacttt cgtcaaagag gaagccttct gccttcacgt
    27181 ggttggcaat gagggcaccg tcttggttgg cacgtttgat gttttcaatc acgagacgcg
    27241 catcgttgtt acggaagtca agatacactc cacctcctac caagccttcc ttcttcaagt
    27301 ttggctggcg ttccaagact tgatccttgc tcaaaacctt gttcgcagct gacgtgttgc
    27361 tcacacctgc taaaaggtcg tacaagtcca tggctacttt aagacggaag aggctaaagg
    27421 ttgctccatc ttcatcgtaa actggtaaga gcattggatc tgattttgga atgtgtggag
    27481 cgatttgttg aaccactgca cgttcagaaa ccgtatctga gaccacttct acgtcaaatt
    27541 gtttgaggta acgaagtcct ccgtgaacca attttgttga acgactagat gttccttctg
    27601 caaagtcttg catttcaatc aaaccagtct caagaccgct agctgccgcc tgcaaggcta
    27661 caccagctcc tgtgattcct ccaccgataa tcaagaggtc cagggtacgt tcctgcattt
    27721 ttttaattga caattcacgt gttttctttg aaaattccat atttacacac tttctaaata
    27781 aatcgcttta ttctgccagt attagtcgtc tacttccgca aagacttgag ttgctttcac
    27841 agccttcttc cagcccttgt agagttgttc cttgcgagat tcgttcatag atggctcaaa
    27901 gagttctcct gtctcgttca agagtttcaa ctcgtccaag tctttccagt accctactga
    27961 caaacctgct aggaaggccg ctcctagagc tgttgtttcc aggtttttag cacgtgcaat
    28021 gtcaatgcct aaaatatccg cctggaactg catgaggaag ttgttcatgg ctgcaccacc
    28081 atccaccttc agtacttgaa tggcggtctg agtatccact tgcatggtgt cgatgatatc
    28141 acgcacttga taagcaatag attgcaaagt cgccttgata aagtcttctt tgcttgttcc
    28201 acgagtcaaa ccaaagacgg aaccacgagc attttggttc cagtatggag cgcctagacc
    28261 tgtaaaggct ggaacgacat aaacttcatc gttgttgtga gaatcacgag cgtatttttc
    28321 agattctggt gaattttcaa ccatgcgaag accgtcacga agccactgaa tagcacttcc
    28381 tgcgatgaag atagaacctt ccaaggcata ataaacctta ccgttgattc cgtaaccaat
    28441 ggttgtcaag aggttgtttt cagacaactg catctcttcc ccagtattca tgatgatgaa
    28501 agagcctgtt ccataagtat tcttaaccat acctggctca aaagccaact gtccaaagag
    28561 ggctgcttgt tggtccccag ccatacctga gattggcacc tctccaccgt agaaatggaa
    28621 tggagctgtc ttgccgtaga tttcggagtt agaacgaact tctggaagta tagccttcgg
    28681 aatgttaagg atttccaaaa tctcatcatc ccatttgagt tctttaatgt tataaagcat
    28741 ggtacgagct gcatttgagt agtcagtcac gtgagccgca ccgtcagtca atttccaaac
    28801 caaccaagta tcgatagtac caaagagcaa ttcccctttt tctgctcgct cttgagcacc
    28861 ttctacatga tccaaaatcc aacgaacctt ggtagcagag aagtaagcat caataatcaa
    28921 accagtcttt tcatggaatt tttccacata accttggctt tttagttgct cagccaaagg
    28981 tgctgtctgg cgtgactgcc aaacgatagc attgtagata ggaagtcctg ttttcttatc
    29041 ccagacaacc gttgtttcac gttggttggt aatcccgatt gcctcgattt gatttggctt
    29101 gacaccactt tcgatgaaag cacccgcaat aactgactga acagagttcc aaatttcatt
    29161 ggcattgtgc tcaacccaac ctgcctgagg gaaaatctgg gtaaactctt tttgactcga
    29221 gctaaccttt tccccttttt tgttgaaaat gatggcacga gaacttgtag ttccctggtc
    29281 aatggccatg atgtattttt cttgtgacat gtactgtcct cctgataaag atcttgaggt
    29341 gtttcctctt tacacttact agtatacaaa ataaagcgct ttcttgttta tcaacttttt
    29401 ttaattttta aaaaaatgtg aggagattgt gtgaatttca caaaaaagac ctggattaac
    29461 caagcctttt aagtgaataa taactggcga atcgctacca aatcctccat atccaagtca
    29521 ttttttaaat aatagactgg tgtctgttcc ttcttatgaa tcgggttatt ggtaaccagc
    29581 aaatcataat gccgactagg gtcataagct tcaatggtaa taaaacgatt gtattccaaa
    29641 taccgtttca aaatggctgc catccttgaa aagacaagaa aaccagatgt caaatccaga
    29701 ccaatccgca tatgctggcc accgttttca gccatatatt cgattaactg gagccattcc
    29761 cagagaatct tcttatctaa atctgtcccc tgttgaaaag caggtagagc atgaaaaatc
    29821 tcctctgctg tctctttaaa atcatgttcc atcagtaaat atggatgacg attctctaac
    29881 tggtacttgt agcgatcctg taaaatatag cccttataga gatagacttg agcacaaagc
    29941 tgactgagtt cataggtgac atggtcctct gtataatccc ccaatagttc ctccttcttc
    30001 atttcttgaa tcaattgcgt cagtaaatct gccaactgcc ctccaaaacc aagaatatac
    30061 tccatagtat gaagaggaag aatgcgatga gataggagaa aagagaagaa tatcatcatc
    30121 tcaccatcct caactcctag tggaatatgt tgcccagcaa aaaaggacgg aacctttctc
    30181 agcaaacgaa ggtagaaaat attgtcaaaa taccctcgca ttttctcttc tatgacttga
    30241 aactgacaag cattgacccg aagacgttgt tgactgatgt gagcccagag aaccaagtcc
    30301 aatttctgcc ccgcagacaa acttgcaccg cagatttcct ctaaattggc aatctcctgt
    30361 tttctctctg gtttctgcat gtgaccttcc cattcctgac tggaccagac ctttcggaaa
    30421 agacagaaat agaaatagcg aatctgatgc tctggacctc gccaacggcc attttggatg
    30481 gataaatcaa attctgacaa aatctgattt aaaccagcca agtgacgacc aagcgtagcc
    30541 tcgctaatca ccaattcttg agccagctga tgggctaaaa actgttggtg gtagagaaga
    30601 taaaccaaaa tctggtattt aacagcacta tccaaaaaca agttccgaat atctctcccc
    30661 ttggtagctg caccgataga cagacgcaga ttttcatctt ctgagtgaat agtcagctct
    30721 aagccactat ccaaagcctt gtcattgagc agggtgacat atttggttag ggttgctttt
    30781 gaaaatcctg tttcttccat tgcagccttg acggtcgtct gagactcttg taatagaaag
    30841 gaaaggattg aaaattgacc acactcggct ttctccatca aatctcctaa atacatttgt
    30901 tatccctttc attttctacc ttaagcatag cataaatctt acaaatgctg aaataatctg
    30961 tttctctttt tattttcatg ctgatttcct ggtccattat cctgaaaatc agtaaacaca
    31021 cggctccccc tctgggcatt tttatgctaa aatagtagct atgaataaaa ttattaaaac
    31081 tatatcagaa agcggagcct ttcgtgcttt tgtccttgac agcacggaaa ccgtccgcac
    31141 tgctcaagaa aaacaccaaa cccaagctag ctcaactgta gcgcttggtc gaactcttat
    31201 cgctagccag attctcgcag ccaatgaaaa aggaaatacc aaacttacag ttaaggtgtt
    31261 gggatctagc tctctaggtg ctattatcac cgtcgctgat accaagggga acgtcaaagg
    31321 ctacgttcaa aatcctggtg ttgacatcaa aaagactgcg actggtgaag tcctagtcgg
    31381 accttttgtt ggaaatggtc aattcctcgt tatcacagac tacggtactg gaaatcctta
    31441 caactctata actcccctca tctccggaga aatcggtgaa gaccttgcct tttaccttac
    31501 tgaaagccaa caaacgcctt cagcggtcgg cctcaatgtc cttttggacg aggaagacaa
    31561 ggtcaaggtt gcaggtggtt tcctagttca agtcttgcca ggagccaaga aagaagagat
    31621 tgctcgcttt gaaaaacgca tccaagaaat gccagctatc tctactcttc tcgaaagcga
    31681 cgaccatatc gaagccctcc tcaaggctat ctacggggac gaagcctaca agcgtctttc
    31741 tgaagaagaa atccgtttcc aatgtgactg tagccatgaa cgctttatga acgctcttgc
    31801 cagccttcca agctcagact tacaggaaat gaaagaagaa gaccacgggg cagaaatcac
    31861 ttgtcaattc tgccaaacta cttacaactt tgatgaaaag gacctggagg aactcattcg
    31921 tgacaaatct taatacacct tttatgattg gcaatgttga gattcccaat cgtaccgttt
    31981 tagcgcctat ggctggcgtg accaactcag cctttcgtac catcgcaaaa gagctcggag
    32041 ctggactcgt tgtaatggaa atggtctctg acaaaggaat ccaatacaac aacgaaaaaa
    32101 ccctgcacat gcttcatatc gatgagggcg aaaaccctgt ctctatccaa ctttttggta
    32161 gcgatgaaga cagcctagca cgcgcagcag aattcatcca agaaaacacc aagaccgata
    32221 tcgtcgatat caacatgggc tgccctgtca acaaaatcgt gaagaacgaa gctggagcta
    32281 tgtggctcaa ggatcctgac aagatctact ctatcatcaa caaggttcag tctgtccttg
    32341 atatccccct tactgtcaaa atgcgtaccg gatgggcgga cccatctctg gcagtagaaa
    32401 atgccctcgc tgctgaagct gcaggtgttt ctgccctcgc catgcatggc cgtacccgtg
    32461 aacaaatgta tactggccac gcagaccttg agacccttta caaggttgcc caagctctaa
    32521 ccaagattcc attcatcgcc aacggtgata tccgtactgt ccaagaagcc aagcaacgca
    32581 tcgaagaagt tggtgctgac gcagtcatga ttggccgagc tgccatggga aatccttacc
    32641 tcttcaacca aatcaaccat tactttgaaa caggagaaat cctacctgat ttgacctttg
    32701 aagacaagat gaagatcgcc tacgaacact tgaaacgatt gattaacctc aaaggagaaa
    32761 acgtcgccgt tcgtgaattc cgcggcctcg ctcctcacta tctccgtgga acatctggcg
    32821 ctgccaaact ccgtggagcc atttcacaag ctagcaccct ggcagagatt gaagctctct
    32881 tgcaattgga gaaggcttaa tagtttaaaa cccgtaactc tcttaaagag tctcttgagt
    32941 gccgccattc tttcctcatc aaaaaaactc cgtagtctct agcgccataa atccggctag
    33001 agattacaga gttatttttt aatctaaact tcctacaagg gtatagtatc tactgaaagg
    33061 atatggtatt tgtagggaat actttaaaga gttcttacag gaagccagca ttaacgagtt
    33121 acattaggtt tagtttaccc atttaccatt ggcattgact ctatagccac ctacagttgt
    33181 gttgactgca agggcacctg agccattgac atagtaccat ttgtctgata ctttgaacca
    33241 ttggctttct ttcatagccc ctgatgcttc aagatagtac catgtatctc catctttcag
    33301 ccaacctgtt gccatcgaac cgttagcatt
//
LOCUS       DBEJKC010000021        32835 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.021, whole genome shotgun sequence.
ACCESSION   DBEJKC010000021 DBEJKC010000000
VERSION     DBEJKC010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32835
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.021"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(322..1170)
                     /gene="dprA"
                     /locus_tag="ACL3G6_000982"
     CDS             complement(322..1170)
                     /gene="dprA"
                     /locus_tag="ACL3G6_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HGR0545536.1"
                     /translation="MKITNYEIYKLKKSSLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPDSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(1266..1955)
                     /locus_tag="ACL3G6_000983"
     CDS             complement(1266..1955)
                     /locus_tag="ACL3G6_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HGR0545537.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEIFKNEN"
     gene            complement(1967..2845)
                     /locus_tag="ACL3G6_000984"
     CDS             complement(1967..2845)
                     /locus_tag="ACL3G6_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR0545538.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2835..3704)
                     /gene="licA"
                     /locus_tag="ACL3G6_000985"
     CDS             complement(2835..3704)
                     /gene="licA"
                     /locus_tag="ACL3G6_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HGR0545539.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIEFAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            complement(3721..4743)
                     /locus_tag="ACL3G6_000986"
     CDS             complement(3721..4743)
                     /locus_tag="ACL3G6_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribitol-5-phosphate dehydrogenase"
                     /protein_id="HGR0545540.1"
                     /translation="MINQIYQLTKPKFINVKYQEEVIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4748..5455)
                     /locus_tag="ACL3G6_000987"
     CDS             complement(4748..5455)
                     /locus_tag="ACL3G6_000987"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HGR0545541.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLHKERIIITKGGADRNTSIEKIIEAIDAYRPL
                     TSEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5791..7278
                     /gene="tacF"
                     /locus_tag="ACL3G6_000988"
     CDS             5791..7278
                     /gene="tacF"
                     /locus_tag="ACL3G6_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HGR0545542.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFMYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7288..8091
                     /locus_tag="ACL3G6_000989"
     CDS             7288..8091
                     /locus_tag="ACL3G6_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR0545543.1"
                     /translation="MKQLTVEDAKQIELEILNYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8093..8902
                     /locus_tag="ACL3G6_000990"
     CDS             8093..8902
                     /locus_tag="ACL3G6_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR0545544.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(9177..12353)
                     /gene="carB"
                     /locus_tag="ACL3G6_000991"
     CDS             complement(9177..12353)
                     /gene="carB"
                     /locus_tag="ACL3G6_000991"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HGR0545545.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(12666..13745)
                     /locus_tag="ACL3G6_000992"
     CDS             complement(12666..13745)
                     /locus_tag="ACL3G6_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HGR0545546.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            complement(13795..14718)
                     /locus_tag="ACL3G6_000993"
     CDS             complement(13795..14718)
                     /locus_tag="ACL3G6_000993"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HGR0545547.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            complement(14737..15258)
                     /gene="pyrR"
                     /locus_tag="ACL3G6_000994"
     CDS             complement(14737..15258)
                     /gene="pyrR"
                     /locus_tag="ACL3G6_000994"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HGR0545548.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            complement(15469..16098)
                     /gene="nth"
                     /locus_tag="ACL3G6_000995"
     CDS             complement(15469..16098)
                     /gene="nth"
                     /locus_tag="ACL3G6_000995"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HGR0545549.1"
                     /translation="MVLSKKRARKVLEEIITLFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            complement(16098..16640)
                     /locus_tag="ACL3G6_000996"
     CDS             complement(16098..16640)
                     /locus_tag="ACL3G6_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HGR0545550.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            16810..17127
                     /locus_tag="ACL3G6_000997"
     CDS             16810..17127
                     /locus_tag="ACL3G6_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGR0545551.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EQLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FEF"
     gene            17366..18925
                     /locus_tag="ACL3G6_000998"
     CDS             17366..18925
                     /locus_tag="ACL3G6_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0545552.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLSKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIHSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(18969..19868)
                     /gene="htpX"
                     /locus_tag="ACL3G6_000999"
     CDS             complement(18969..19868)
                     /gene="htpX"
                     /locus_tag="ACL3G6_000999"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HGR0545553.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(19870..20430)
                     /locus_tag="ACL3G6_001000"
     CDS             complement(19870..20430)
                     /locus_tag="ACL3G6_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HGR0545554.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            20524..21237
                     /gene="rsmG"
                     /locus_tag="ACL3G6_001001"
     CDS             20524..21237
                     /gene="rsmG"
                     /locus_tag="ACL3G6_001001"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HGR0545555.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            21491..22774
                     /locus_tag="ACL3G6_001002"
     CDS             21491..22774
                     /locus_tag="ACL3G6_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HGR0545556.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMLATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(22969..24540)
                     /gene="ffh"
                     /locus_tag="ACL3G6_001003"
     CDS             complement(22969..24540)
                     /gene="ffh"
                     /locus_tag="ACL3G6_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002902912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HGR0545557.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKVLAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(24552..24884)
                     /locus_tag="ACL3G6_001004"
     CDS             complement(24552..24884)
                     /locus_tag="ACL3G6_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HGR0545558.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            complement(24975..25352)
                     /locus_tag="ACL3G6_001005"
     CDS             complement(24975..25352)
                     /locus_tag="ACL3G6_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HGR0545559.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTNRYQVDGQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            25424..26728
                     /locus_tag="ACL3G6_001006"
     CDS             25424..26728
                     /locus_tag="ACL3G6_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGR0545560.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            26741..27547
                     /gene="yidA"
                     /locus_tag="ACL3G6_001007"
     CDS             26741..27547
                     /gene="yidA"
                     /locus_tag="ACL3G6_001007"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HGR0545561.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETDTGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTLVL"
     gene            complement(27602..27673)
                     /locus_tag="ACL3G6_001008"
     tRNA            complement(27602..27673)
                     /locus_tag="ACL3G6_001008"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(27638..27640),aa:Arg,seq:cct)
     gene            complement(27715..28062)
                     /gene="rplS"
                     /locus_tag="ACL3G6_001009"
     CDS             complement(27715..28062)
                     /gene="rplS"
                     /locus_tag="ACL3G6_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HGR0545562.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(28181..28510)
                     /gene="crcB"
                     /locus_tag="ACL3G6_001010"
     CDS             complement(28181..28510)
                     /gene="crcB"
                     /locus_tag="ACL3G6_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGR0545563.1"
                     /translation="MVIVYLAIACGFGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(28504..28878)
                     /gene="crcB"
                     /locus_tag="ACL3G6_001011"
     CDS             complement(28504..28878)
                     /gene="crcB"
                     /locus_tag="ACL3G6_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGR0545564.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            complement(28875..29141)
                     /locus_tag="ACL3G6_001012"
     CDS             complement(28875..29141)
                     /locus_tag="ACL3G6_001012"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HGR0545565.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(29257..29700)
                     /locus_tag="ACL3G6_001013"
     CDS             complement(29257..29700)
                     /locus_tag="ACL3G6_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HGR0545566.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            29804..30739
                     /locus_tag="ACL3G6_001014"
     CDS             29804..30739
                     /locus_tag="ACL3G6_001014"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HGR0545567.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNITDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            30835..31077
                     /locus_tag="ACL3G6_001015"
     CDS             30835..31077
                     /locus_tag="ACL3G6_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HGR0545568.1"
                     /translation="MKKDIHPEYRPVVFMDTTTGYQFLSGSTKRSNETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(31134..31712)
                     /locus_tag="ACL3G6_001016"
     CDS             complement(31134..31712)
                     /locus_tag="ACL3G6_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HGR0545569.1"
                     /translation="MVRNYWKAKSWLLVLALSFLILSPAGAQESLSFFFVKITDASKT
                     VKNGGQTETQKLVTKMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSIAHYGRVETAISFLPSSMEIEPTDESGT"
     gene            complement(31687..32700)
                     /locus_tag="ACL3G6_001017"
                     /pseudo
     CDS             complement(31687..32700)
                     /locus_tag="ACL3G6_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            complement(32703..32835)
                     /locus_tag="ACL3G6_001018"
                     /pseudo
     CDS             complement(32703..32835)
                     /locus_tag="ACL3G6_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         9835 a         7174 c         6067 g         9759 t
ORIGIN      
        1 tttcccttat actcaatgaa aatcaaagcg caaactagga agctagccac aggttgctca
       61 aagcactgct ttgaggttgt agataagact gacgaagtca gctcaaaata ctgttttgag
      121 gttgcagatg gaagctgacg tagtttgaag agattttcga agagtattat atgagaaaaa
      181 tcctctactc tactaatcca cttagaaaaa acgcatatta tcaagtgtta aaaacttgct
      241 aatatgcgtt ttattatgga aatgttgggt tcattttctc ttaaaattga ttttttctta
      301 gaattctagc ttaggtcatt tttaaaattc aaattccgca agaacatctt gcccactggt
      361 gaccaatttt gctccttctt gaatcaaatg atggcaaccg tctgatagtc catctaaaat
      421 gctatcagga atagcaaaga catcgcgtcc ttcttccatt gctcgctcac acgtaatgag
      481 actacctgaa cgcatcttag cctctgctac aatcacacca cgacaaagtc cagcaatgat
      541 gcgattacgg gcaggaaaat gaaatttcag aggttgttcg ccaggtccat attcacttag
      601 aaccagatgg tcattgccga tgtagtcttg caagcgttta ttggctttag gataaaacac
      661 atccagtcct gttccaatca ctgcaatggt ttttccgcca ttctgaagag ctgccatatg
      721 agctgctgtg tcaatgccct tggccagacc actgacaata accagttcat tttccaagcc
      781 ttgaatgact ttttcaactg acttagctcc ctgtttgcta caagcacgac tgcccacgac
      841 cgctaccttc gggaatttca ggaggtcaag atttcccttg taaaataaaa gtacaggcgc
      901 atcatatatt tcactcaaat cccaaggata acagtcatct aaaatagaga aagatggaaa
      961 tttttgaaac tctttcgaca aatgcgcatc gtctatctga aaataacgtt ccataaaaac
     1021 ggctggatta cggcaacctg atatatctgc aatatcaccc aacaaaagct cctgatcaac
     1081 attttcaccg tattctagaa ctttcaaaat ctgttgattg gtcaaacttg atttttttaa
     1141 cttatagatt tcatagtttg tgattttcat aaataactcc atttcttttt ctactcatct
     1201 atctattcgt aaaagttcgt aaaaaatcaa aaaacatccg actattttgt cagatgttgg
     1261 aatctttaat tttcgttttt aaaaatttct tctaatttac gatagtcttg gacactatcg
     1321 atctcataaa tgctattgcc ttctaattct tcaacataga catctagctc tttgatatta
     1381 tccttaacca tattgtccca atagagatca acaaattcgc cacttgcata agccttatcg
     1441 ataaagctga caatcttttc tgcagttgga gcatcccaga aggatacacc actaaggatg
     1501 cgacctgcct tgctatcaac aataatgtct tgaaccttgt agtcatctcc atagaccaag
     1561 aaccattcgt tggtacaatc ttcacgataa acactaaaat aagtcgaacg agtcaaatca
     1621 ttgcggaaca tatttttaaa gagataattg tcagcatcaa taacatagct gttggccaat
     1681 tcttctttta caagatagag agagtaaaag ttattgtagt cagcgtattt atcattgaaa
     1741 acgaggcgaa caccgtattt ttcttttaag taatcgaatt gttctttaag ataaccaaca
     1801 atgatgatga tgtcattgat tcctttttct ttgagaaact caatttggta ctcaattaag
     1861 ggtttttgat taacctgaac caaggcttta ggggtatttt cagtcatagg acgcaagcga
     1921 gttcccaatc ccgctgctaa gataatggct ttcacacgaa tctcctttat tctttaataa
     1981 taatataaac tccagcaatg acgacaagtg acgtcataat ggtcagcata tctagcggtg
     2041 cacccaagaa aacaactgca aacaagaccg tccatactac atagctcacg ttcaagcctg
     2101 tagccttggc tggttgcaag cgattgatag cgatataata agccaagtag gaaatcatat
     2161 caaaggctgc aaaaacaatc atgagaccta gcaattgtcc attggctact gcagtaaatg
     2221 actgatgaga gaagagcaca atcacaagat aggacaagaa cgaagttact tgacggatta
     2281 agagggcttc gatttcactc aattcacttt ccatggcaaa agagctaaga acactctcac
     2341 ttccccatgc aatagcacaa accaaagcac aaagaatccc aatgtagaaa gaattaacct
     2401 gttcaacctt ataggtctga gcaataatcc ctccaataat caagacaatc ccaaatacag
     2461 tatttttcga aatcttgtgc ttcaaaaaga agaaagccaa tagaactgaa atcgcagggt
     2521 aaatagccga tacagatgaa gctaaagaac ttccgatata cttaactgca taaagattgg
     2581 cctgcatacc gatagggcct gctagcaagg ctccgatgat aacactgaca ttgcgaatat
     2641 ttaagaaaat tgagaggcga actttccctt cttttaccaa gagaaaagct agtaagataa
     2701 agatgctcaa aaaatcatga gctgcagcca ccacaaaggg tgacaaatct gtaaaaatcg
     2761 aaaagatata agcactaacc gttagaccca agccccagaa aatacctgag agaaggccaa
     2821 aaggaactcc gtttttactt ttcatctgaa cctccataag aagccaaacc tttaacagct
     2881 ctttggtaac gattcacacc atagtcacca aaatcttcac cttgctcttc cttatagaca
     2941 gtccatagac tccaaatagt atcttgtaaa attttataaa tagcaatctt ttcatgagaa
     3001 accggtgttt ggtcactctc atagtgagat aagaaagttt cttcctcttg ggaagtgaat
     3061 tcagactcta aaaagagggc agccaaatcc cacattggat cattcattga tgaatattcc
     3121 cagtcaatca aataaagtcg tccttgaggt gattcgataa agttttcagg caccaaatcg
     3181 atatgacaag attttctgtc aacacctaag tcagccagtc ttttctctaa ggagaagact
     3241 gcatttctaa cagattcata gttggcataa ggaatttgtt cttcaatcaa ggattcgtat
     3301 tttttgattt cttcaaaagg agcaaattct cctcttaatt ccttagcaga cgtatgaata
     3361 gtttgtaata ttggagcaat tttgtcgaac ttggtcttga ttgacgttga atcaagcgta
     3421 atcgcaaatt cgatatactc atttactttg ataccagctt caatatcaaa aagataattt
     3481 tttacatcta agcctaaatc ctttagtagt tcaagattgt acttttcatc ttgtcgattg
     3541 ataagctttt ctgtcccttt accaaagaat ttaacaatgt attgcttatt tgttgttttg
     3601 gccaaatagt tttgattggt cattccaccc agttgttcaa cactgaggac ttcctcttct
     3661 tgactaagta aggaagaaat tttttcttta atgattttct ccacaattaa cctccagtac
     3721 ttatacttcc cacttaaaca ctgttttaaa ggctgtgttt aaatcggttg caaagacacg
     3781 atgaatatct ttaatttctc ttacaggttc ttctagataa aggatatttt taagacgatt
     3841 ggcaaatttc ttgacttcca tcatttggat agcattttca aaatcaatgc gaccagaacg
     3901 agatgaccca accaaaatca agcccttttc taaggcatcg cgagtattga gattgacttt
     3961 atattcgcta actcccatca tgagaatcgt tccctgagga cgaatgtagc gaatcaagtc
     4021 attaatagct ggtccagtac catcaccacc acaacattca aaagcatggt caaaggccaa
     4081 atcttcagga atattatccg taatatagca ttctttggca aatgagaaga gttccaactt
     4141 ttcccaatga cgaccaataa ccacaatctc tgcttctggc aaagtatagt tgataatatt
     4201 ggcaaccaca aaagctaaac ttccatctcc aataacggcg atccgctccc gcttgctatg
     4261 agcaagagtc aatagacgat tcatagcgtg catgcccaca ctgacaaact ctgtaatggc
     4321 tgcaaccgta tcttcaatag catcataagc caccacacga tctttaggga gagaaacaaa
     4381 ctctctcata aagccatcaa atccactaga caagaaatgg gtccctgtca tgtagttttc
     4441 atagaattct tcatcactct gcataggaga ctgattggga atcatgacaa ctttttgacc
     4501 aacctcgtag gttccggtcg ggtcagaaat gacggttcca catgactcgt gaatcattgc
     4561 cattggaagc tttttattca aaatcttggg atcacgtttt ccctgatagt aacgctgatc
     4621 cgcatgacag acagccatgt agttgggacg gataaggata tgattctctt ggtcaataac
     4681 ctcttcctga tatttgacat tgataaactt aggcttagtt agttgataaa tttgattaat
     4741 cattttacta gtctttctca atcatacttt ttgcaatctt caaatctgtt acggttgtaa
     4801 tcttcagatt tgagtattca cctttggcca aggccacatc ttttcctttg atcacaaaga
     4861 ttttacatgc atctgtcaag atttccttct cttcatcaga aagagatcca taaaggtcca
     4921 tgaagtcctt gcaacggaat gtttgaggtg tttgtccttg ataaaggtga gcacgatttg
     4981 gaatatctgt aataaattga ccattggtac tttcaacgat agtatcaacc gcttctacca
     5041 ctgtgtccac tgcgtcatga ttttgggcaa gttggatatt gtcctgaatc atgcgaagtg
     5101 taataaatgg acgaacagaa tcgtgggtaa caacgatatc ctctgaagta agcggacgat
     5161 aagcatcaat ggcttcaatg attttctcaa tacttgtatt gcggtcagca ccaccctttg
     5221 taatgatgat acgttccttg tgaagaggaa gatatttatc tacaagatct tctgcatgag
     5281 aaacccagtc tccatgaacc ccaactacaa ttttttcaat acttggctcc aagacaaatt
     5341 tttcaattgt atgaatcaaa ataggtcgat cacctagctc taaaaattgt tttggcaagt
     5401 tactgattcc catgcgtgtg ccagttccac cggcaagaat tcctgcataa atcatctatt
     5461 ttctcctttg tcttactaaa aaaacttatt ctctctatta taccacaatc tagtcctatc
     5521 ataaaagaaa tactggtcct ccccttctag aataggagaa ttatgcagtt ctattattca
     5581 aagaaactag ttcatttcta gtaatgacta ggaattctgt agcaattact aataaatggc
     5641 tgcgaaattt tagagtcctt cagaataata tactttcctt aaagaaaact taaaatttaa
     5701 gatttgaaac ttcaaagtga ttacttgact tactgccctt catttcttat tagctaactt
     5761 tatgatataa tgaaaaacga ggtaaattga atgaaaagta taaaattaaa tgctctatct
     5821 tacatgggaa ttcgtgtctt gaatattatt tttcccatcc taactggaac ctatgtcgcg
     5881 cgtgtcttgg accgaactga ctatggttac ttcaactcag tcgacactat tttgtcattt
     5941 ttcttgccct ttgcaactta tggtgtctat aactacggtt taagggctat cagtaatgtc
     6001 aaggataaca aaaaagatct taacagaacc ttttctagtc ttttttattt gtgcatcgct
     6061 tgtacgattt tgaccactgc tgtctatatc ctagcctatc ctctcttctt tactgataat
     6121 ccaatcgtca aaaaggtcta ccttgttatg gggattcaac tcattgccca gattttttca
     6181 atcgaatggg tcaatgaagc tctggaaaat tacagttttc tcttttacaa aactgccttc
     6241 atccgtatcc tgatgctggt ctctattttc ttatttgtta aaaatgaaca cgatattgtt
     6301 gtctatacac ttgtgatgag tttatcgacg ctgattaact acctgattag ttatttttgg
     6361 attaaaagag acatcaaact tgttaaaatt cacctaagtg attttaaacc actctttctc
     6421 cctctgacag ccatgttagt ctttgccaat gccaatatgc tcttcacttt tttagatcgc
     6481 ctcttcctcg ttaaaacagg gattgatgtc aacgttagtt actataccat agctcagcga
     6541 attgtgaccg ttatagctgg ggttgtaaca ggtgcaattg gagtgagtgt gcctcgtctc
     6601 agttactatc tggggaaagg agacaaagaa gcctatgttt ctctggttaa tagaggtagt
     6661 cgaatcttta acttctttat cattccactg agttttggac tcatggtttt aggaccaaat
     6721 gccatcctac tttacggtag tgaaaaatat atcggaggcg gcatcttgac ctctctcttc
     6781 gcttttcgta cgattatcct ggccttagat accattcttg gttcccaaat tctctttacc
     6841 aatggctatg aaaaacgtat cacagtctat acagtctttg ctgggctact caatttgggc
     6901 ttgaatagtc tcctcttttt caaccatatc gtggctcctg aatactactt actgacaact
     6961 atgttatcag agacttctct acttgttttc tatatcattt tcatccatag aaaacaactc
     7021 atccacttgg gacatatctt tagctatact gttcgatact ctctcttttc actttccttt
     7081 gtagcaattt atttcctgat taatttcatg tatcctgtgg atatggtcat taatttgcca
     7141 tttttgatta atactggttt gattgtcttg ctatcagcta tctcttatat tagtctactt
     7201 gtcttcacaa aagatagcat tttctatgaa tttttaaacc atgtcctagc cttaaaaaat
     7261 aaatttaaaa aatcttagga gtttaaaatg aaacaactaa ccgttgaaga tgccaaacaa
     7321 attgaattag aaattttgaa ttatattgat actctctgta aaaagcacaa tatcaactat
     7381 attattaact acggtactct gattggggcg gttcgacatg agggctttat cccttgggac
     7441 gacgatattg atttatccat gcctagagaa gactaccaac gatttattaa catttttcaa
     7501 aaggaaaaaa gcaagtataa gctcctatcc ttagaaactg ataagaacta ctttaacaac
     7561 tttatcaaga taaccgacag tacaactaaa attattgata ctcgaaatac aaaaacctat
     7621 gagtctggta tctttatcga tattttccct atagatcgct ttgatgatcc taaggtcatt
     7681 gatacttgtt ataaactgga aagcttcaaa ctgctgtctt tcagtaaaca taaaaatatt
     7741 gtctataagg atagcctttt aaaagattgg atacgaacag ccttttggtt gctccttcga
     7801 ccggtttctc ctcgttattt tgcaaataaa atcgagaaag aaattcaaaa atatagtcgt
     7861 gaaaatgggc agtatatggc ttttattcct tcaaaattta aggaaaagga agtcttccca
     7921 agtggtacct ttgataaaac aatcgattta ccctttgaga atttaagcct tcctgcacct
     7981 gaaaaatttg atactatttt gacacaattt tatggagatt atatgaccct accaccagaa
     8041 gaaaaacgct tctacagtca tgaatttcac gcttataaat tggaggatta ggatgcaata
     8101 tttagaaaaa aaagaaatta aagaaattca actagccctg ctggactata ttgatgagac
     8161 ttgtaagaaa catgatattc cttattttct cagttatgga accatgcttg gagccatccg
     8221 ccacaaaggt atgattcctt gggatgatga tattgatatt tccctttatc gtgaggatta
     8281 tgagcgttta ctgaagatta ttgaagaaga aaatcaccct cgctacaagg ttctttccta
     8341 cgatacatct tcttggtact tccataattt cgcatcgatt ttggacactt ctactgttat
     8401 agaagaccat gttaagtaca agcgtcatga taccagcctt ttcatcgatg tcttcccaat
     8461 tgatcgattt acagacttga gcattgtcga caagagctat aagtatgtgg ctcttcgtca
     8521 actagcttat atcaaaaaat cacgagcagt tcacggtgat agcaaactaa aagattttct
     8581 tagattatgt agctggtacg ctctccgatt tgtcaatcct cgctactttt acaagaaaat
     8641 tgatcaacta gtcaaaaatg ctgtaaccaa cactcctcaa tatgaaggag gagttgggat
     8701 cggtaaggaa gggatgaaag aaatcttccc agttgatacc tttaaagaac tgattttaac
     8761 tgagtttgag ggccgtatgt tgcctgttcc caaaaaatat gaccaatttt taacccagat
     8821 gtatggcgat tatatgacac caccatcaaa agaaatgcaa gagtggtata gtcatagcat
     8881 taaagcttat cgcaaaaact gattgagggg tattatacaa actactaaga tagaggttat
     8941 tcaaaaacat aattttagta gaaaatgaaa tacatattcc cacaataaaa cgcatcatat
     9001 caaggttttt gaaaaacctt gatatgatgc gttttataat tttaaagact tttttctata
     9061 gtagattgaa ataagatgcg aacgaatcaa ttagaaaatt caaattaatt tctagaaata
     9121 ttttagtatc cctgtgtact gttctaaatt cagtctgcta tatcttattt ttctatttaa
     9181 atcgcttctg taacaaagct acgactttca agtaccttaa gcatggcatt agctgtatct
     9241 agcgctgtga agaggggcac cccgtgttca atggctgaac gacgaatttg ctcaccatct
     9301 tcgtcagcag ttcgttttgt tcctactgtg ttaatgatag cttgaattct tcctttgcgt
     9361 acaaaacttg ggatatcctt atcgtcatca ccaatcttac caacaggttg ggcttgcaag
     9421 ccatggctag caaagaaggc tgctgtccct tctgtcgcaa ggattccata accaatgttt
     9481 tggaaacgac gagccaagtt caaggcttct tctttggcat catcagcgat ggtaaagacg
     9541 acattaccaa aagttggcaa gtgtagataa gaagcttcaa aggctttata gagagctttt
     9601 tccaaagtag catcagaacc cataacttca cctgttgact tcatttcagg accgagcaag
     9661 ctgtctacct tagctagttt ggtaaaggag aagacaggtg ccttgatatg aacacgggtg
     9721 ctttcagggt aaagtccatt ttggtagcca agttctgata aactttgacc aagaatgagc
     9781 ttggtcgcta cttgagccat aggaatattg gttaccttag ataggaatgg aacagtacgg
     9841 ctggcacgtg gattgacctc aataacgtag actttttcat ccttgataac aaactggatg
     9901 ttcatcattc caaggcagtg aagaccgatt gctaagcgtt tggtgtagtc tgcgatggtc
     9961 tcctgaacct tttgcgacaa ggtttgtggt gggtaaacag ccattgagtc acctgagtgg
    10021 acaccagcac gttcgatatg ctccatgata ccaggaatga gtacatcttt accatctgaa
    10081 atggcatcaa cttcgcactc ttgcccaacg atataagagt cgacaagaac tgggtgatct
    10141 ggactagcct taacagcagt tcgcatgtaa gaacgaaggt cttcttcgtt ttcaacgatt
    10201 tccatggcac gtccaccaag tacataagat gggcggacaa gaactgggaa gccaatctta
    10261 cgagctgcaa gagctgcttc ttcttcattg gtagccgttt gtcctggtgg ctgtggaata
    10321 tccaattctt tgagagcttg ctcgaagagg tcacggtctt cggcacggtc taggtcagca
    10381 acctgtgtac caaggatggt cacacctgct tttgccaatg gctccgcaag gttgatggct
    10441 gtttgaccac cgaactgaac gataactccc tttggttgtt ccaagtcaat gacgttcata
    10501 acatcttcga atgtcaatgg ctcaaagtaa agcttatctg atacagagaa gtctgttgaa
    10561 acggtctctg ggtttgagtt catgatgata gcttcataac cagctgcctg gatagcctta
    10621 acagagtgaa cggttgcgta gtcaaactca accccttgac cgatacggat tggacctgaa
    10681 cctaggacaa gtacagattc tttatcagat ctgatagatt cattttccca accataggtt
    10741 gaatagaaat atggcgtttc ggagtcgaac tctgccgcac aagtgtctac catcttataa
    10801 actggaacaa tcttgttttc caagcgaagt tggcgaactt tatcatcagt cgttccccag
    10861 agttcagcaa tcttacggtc tgaaaaacca ttaagtttgg ctgttttcaa aacttctaga
    10921 tcttgtggat gagcacccaa ttcttgctca atttcaaaga tatgcaagag tttatcaaga
    10981 tagaagatat caatttttgt aagctctgca atttcttcag gtgtgtagcc acgacgaatt
    11041 gcttctgata cgtagaagag acggtcatct tgggctttga caaccttttc aatcaaggca
    11101 tcatcagaaa ctgctgcaag ttcaggtatt tcattgtggt gcaccccaat ttcaagggag
    11161 cggcaggcct tgagaagaga ttcctcgatg ttacgaccga ttgccatgac ttctccagtc
    11221 gccttcattt gtgtaccgag acggcgttca cccttttcaa acttgtcaaa tgggaaacgt
    11281 ggaatcttag caactacgta gtcaagggct ggttcaaaca tggcataggt tgaacctgta
    11341 actgggttta taacctcatc caaggtcaaa cctactgcaa tcttggcagc caacttagca
    11401 atcggatatc ctgtcgcttt agaagcaagg gctgacgaac gtgatacacg agggtttact
    11461 tcgataacat aatacttgaa gctgttagga tcaagagcta gctgaacatt acatccacct
    11521 tcaatcttga gggcacgaat aatgctcaag ctcgcatcac gaagcatttg gttttcatag
    11581 tctgacatgg tttgcgcagg ggcaaataca atggaatccc ctgtgtgaat cccaactggg
    11641 tcaaagtttt ccatgttaca aacaaccaag gcattgtcag ctgagtcacg catcacttcg
    11701 tattcaattt ccttgaaacc ggcaatcgaa cgctcaatca aacattgggt aacaggtgac
    11761 aatttcaaac cattttcagt gatttcacgc aattctttct cgttggcaca cataccacca
    11821 ccagtaccac caagggtaaa ggctggacga acgatgactg ggtagccaat tgtcgctgca
    11881 aaggcaactg cttcttctac tgtgttaaca atttcagatt ctggaatggg ttgttcaagc
    11941 tcttccatca attgtttaaa gaggtcacgg tcctccgctt ggtcaatggc agataatttg
    12001 gtacccagaa gttcaacgcc aagctcgtct aggataccat ttttagataa ttccatggcc
    12061 atgttgagac ctgtctgacc accgagtgtt ggtagcaagg catctggacg ttccttacga
    12121 agaatacgtg tcacaaactc aagtgtaatc ggttcaatgt aaaccttgtc agcaatttcc
    12181 ttgtccgtca tgatggttgc aggatttgag ttaaccaaaa caacctcata accttcctct
    12241 ttcaacgaca agcaagcctg agtcccagcg tagtcaaact cagcagcctg gccaataata
    12301 atcggaccag aaccaatcac cataattttt tgaatatcag tacgtttagg catatataag
    12361 atattaaggg cgtcaagcgg acaaagctaa aataggagtt atgacgaaga actgtcagtt
    12421 ctaggaataa ctatcttttt agcaccgtcc gtagcccgta ttcagttcag caaatacgga
    12481 gcacccttct cctttctatt cgtcgcctct cagggcgaca ttaaataaga tacaaaggac
    12541 gaatagaaag cgattgaatt ttagaaaatc aaggaaggat tgacaatcca agttgatttc
    12601 tctacattct gagctttccg tccgtgttca gttacataaa ttctccgacg agcttttact
    12661 cgttcttagt ttgattgttt aaaaacttcc atcatctcga taaactcgtc aaataggtag
    12721 ctagcgtcgt gtggcccagg agctgcatct gggtggtatt gaacagagaa agcaggttgg
    12781 tatctgtggc gcacaccttc cactgacttg tcattgattt cttcgtgggt aataatcaag
    12841 tgctctggca aatcctcgcg gctgactgca taaccatggt tctggctggt gaagtctact
    12901 cgtcctgttg cgatttcacg taccgcatgg ttgaatccac ggtggccaaa cttcatctta
    12961 taggtcttag ccccgtttgc cattgcaaag agttggtgtc ccatacaaat accaaagatt
    13021 ggaatttttc cttgtacacc gcgaatcatg tcgagtgctt gtggaacgtc ttctgggtta
    13081 cctggaccat ttgacaacat aaccccatca ggattgagat ggagaatttc ttcagccgtt
    13141 gtcgaataag gaacaactgt cacgttacag ttgcgtttag aaagttcacg taggattgag
    13201 tgcttgagac caaagtccac tagcaccacg ctcaaaccaa ctcctggagc tggataagac
    13261 gttttagtag aaacctgttt gatattgtct gtcggtaaaa ctgttgcttg gagctggtcc
    13321 gtcacatggt ccatactgtc cccaacatgg gtcaaggttg cacgcatagt accatgctta
    13381 cggataatct tggtaagagc acgcgtatca attcctgaaa tccctggaat ttttttggct
    13441 ttcaaaaatt catccaaggt catttggttg cgccagttgc tagctctacg cgcttcttca
    13501 aaaacaacga ctcccttaca agttggaata atggattcat aatcatcacg attaatacca
    13561 taatttccta ccaaaggata agtaaaggtc aagatttgtc cattataaga ctggtctgta
    13621 atggattctt ggtagccggt catccctgta ttaaagacga tttcgcctgt tacatcaata
    13681 tctgctccga aggccttgcc ttcaaaaact gtgccatctt ctaatactag aattcttttt
    13741 gtcatatttt cacctctcgt ggacgctcac tggcgtcttt taacgtcttg tgttttagtt
    13801 ggcgtttcta ctcgctagta cggattctaa gattgccatt cgaacaaaga caccattggt
    13861 catttgttgg acaatccgtg attttggtgc ttcaaccaag tggtctgcta tttctacatc
    13921 acgattgatt ggagctgggt gcatgaggat tgctgtttct ttcaaacgat cgtaacgttc
    13981 ttgagtcaag ccatgttggg catggtagtc ttcttttgaa aatacagctc cactatcatg
    14041 gcgttcgtgt tgcacacgga gaaacatcat gacatcaacc tgatcaatga tttcatcaat
    14101 ggttacaaac tgtccatagt ctgcaaactc ttgacttctc cattcctcag gtccagcgaa
    14161 aaagagttca gctcccaagc gtttcaaaat ctgcatattg gatttggcaa cgcgtgagtg
    14221 atccaagtca cctgcaatag caactttaag accctcaaag tggccaaatt cctcataaat
    14281 ggtcatcaaa tcaagcaagc tctggctagg gtgttggccc gaaccatctc caccattgat
    14341 gatggaagtc gtaatcgttg gactagcaat caattctcta tagtagtcga cctctggatg
    14401 gcgaatcaca cagacatcca ctcctaaagc agacagagtc aaaatggtgt cataaagtgt
    14461 ctcaccctta ttaaccgaac tagtcttcac atcaaagtca agtcgttcca atccaagttt
    14521 aatctctgcg acttcaaagg acttatgtgt ccgtgtagaa tcctcaaaga agagattgga
    14581 aacaatcgga tggtcttcat agggaagctg ggctccattt ttaaactcaa ttcctcgctt
    14641 gatcaatttc attacttgat cgacagtgag gtcttccatg gacaccacat ggttcaatgc
    14701 ttgttgattt tctgacatgg ctactccttt aactttctaa gcttcttcag taatcagaac
    14761 tctgtcttgg tcatcaagtt ctgtcatctc tacgatgatt tcttcagaac gactggttgg
    14821 gatatttttt ccaacgtaat ctggacggat tggcaattct ctatgtccac gatcgactag
    14881 aactgctaaa ctcacacgcg caggacgacc atgaccgaca atattatcaa tagcagcacg
    14941 gatggtacga cctgtataga gcacatcatc caccaagata acttcgcggt ctgtcacatc
    15001 gacagaaacc aaagaagtat cttctccact tttaacatca tcacggaaag gtttagtatc
    15061 caattccaca acaggaactg aaagattttc taactgcttc aaacgttctt ggattcggtg
    15121 ggcaataaag acaccacgag ttttaatacc agccaagacg atcttattca aatctttgtt
    15181 gcgttcgata atctcataag taatacgcgt aatcgctcgt ttgacggtca attcgtctac
    15241 aacttctttt gttttcatga caaacctcca aaaagaaaag tctccttaaa caaggagact
    15301 tgaaatttat agccaagcga gccctactgc acacagtata gacttcaccc ttctacttta
    15361 tcgcgctcct tgcctgcctc acgggacagg tttaaaggaa tatttagtta tcatttacta
    15421 tagcacaaag catgcttaaa atcaagcaaa aagtttcaat gtagcatctt acaaattgct
    15481 aaaatcatat aattgtgggt actggtcaca ctctggattt tttggatggc aaatggctct
    15541 tccaaaataa atcatggcct gatgggcagc taaccactgc tcaggcggca agatatccat
    15601 gacccgcttt tccacctcaa gtggcgtcgc tgattttttg acaatatcgt ggtgtttgca
    15661 aatacgctcc acatgagtat ccactgcaaa ggctggaatc ccaaatccta cactcatgac
    15721 aacattggct gtcttgcgac caacacctgc caaactctcc aattcttcac gtgtctgagg
    15781 gacttgacca tcaaaatcgt ctagtaactg ttgggcacat tttttaagga atttagcttt
    15841 attccgatac aatcccaagc gagaaatatg tgaagcaatc tcactctctg tcgctacaga
    15901 catagcttgg ggtgttggaa aggcaacaaa gagacctggt gtggccttat ttaccgctgc
    15961 atctgtcgtc tgggctgata acatgaccgc aaccaggagt tcaaaatgat tggtaaaatc
    16021 aagactaggc ttggcatctg ggaagagggt aatgatttct tctagcacct ttcgtgctcg
    16081 tttttttgac aagaccatta ttcatctccg tcaaatagtc cttgtaagcc agcaaaagga
    16141 ctgttttctt ctttctttac tgctttttga gcttggtatt cttcctctgt catgatttgc
    16201 cagtcatttc ctgagataaa tccttgacca gcttcttctt cagccgtcaa gaccttgata
    16261 ggaatgttta gcaggatatt gtctgataca ctctcagcaa ggtcaagctc cccattttcg
    16321 atgggcaaga ccaagtcatc atctaaaact tcttgatcta gctggttagt tgcgccttcc
    16381 atgaaaactt ccgtgactgg ataagattca actaactcaa ctggctccat actgcgactc
    16441 gaagcaagaa caatggtata agatagttga taatctaaga aatacatacg gtcttcatat
    16501 tgtactttcc caactgcaag gatatctttt acatctaaaa tttcttgatt acgtgcacgc
    16561 aggtcatcaa ctaaatctaa cgtttgttca aagttcaaac cttcagactg cttacgaatt
    16621 tcttgaatat ttaatttcat acttcctcca taaagattta ctctcttgat tataccatga
    16681 aaaggctaca aatcagcaca ccaaactttg taattaaaat tcaaaatttt aacatattta
    16741 ctattatagt tttatttttt agtgctatac tatagggaaa gagtacatca gatcaaggag
    16801 gatgctcaca tggaagacaa gaaactcatt caactcctat ccaagttaaa taaaagctac
    16861 caaaactgta aacagggtac ggcagatgat attcgactac aagagctgct aaacactact
    16921 atgcaagagc tcaaaaaaac ggaacagttg aacaacagta tcttaattga tcttgagaaa
    16981 ttttaccaac ctaccagtct tctgattgga ctgggtagcc taaaactaaa cgatcaagca
    17041 cgcactgctt ggcgaaacta tgataaattc cattacgagc atgtcaaaca cgtactaagt
    17101 ctctatggac ctgtttttga attttagagc atagaatttc cagttttctg ttgacaaaat
    17161 ttccttaaag gtataatata aagatactaa tactcggagg taagggagac atgaacaact
    17221 aagtctatca aataaagaac ctttatttag tagatcttgt ttttgtctct ttttgtgtgc
    17281 tcttttatgc tctttttctg gcatgttaat agagtttttt tgacatagac tttgggctct
    17341 actaggtaaa gtagagcttt ttgttatgca ctatgaacat tctagaaagg gaaatcatat
    17401 gataaaaatc aatcatctaa ccatcacaca aaacaaagat ttacgagatc ttgtatctga
    17461 cctaaccatg accatccaag acggggaaaa ggttgctatt attggtgaag aaggaaatgg
    17521 caaatcaacc ttacttaaaa ttttaatggg ggaagctttg tctgatttca ctatcaaggg
    17581 aaacatccaa tctgactatc agtcactggc ctacattcct caaaaacttc ccgaggagct
    17641 gaaaaagaaa actttacacg actacttctt tttagattct attgatttag actacagtat
    17701 cctctatcgt ttggcggagg aattgcattt tgatagcaat cgtttcgcaa gtgaccaaga
    17761 gattggcaat ctatcagggg gagaagcttt gaaaattcag cttatccatg agttagccaa
    17821 accctttgag attctatttt tagatgaacc ttcaaatgac ctagaccttg agacagttga
    17881 ttggctaaaa ggccagattc aaaagaccag gcaaaccgtt attttcattt cccatgatga
    17941 agactttctt tctgaaacgg cagacactat tgttcacttg cgactggtca aacaccgtaa
    18001 agaagcggaa acgctagtag agcatttaga ctatgatagc tatagtgagc agagaaaggc
    18061 taattttgcc aaacaaagtc agcaagctgc taacaaccaa agagcctacg ataaaaccat
    18121 ggaaaaacat cggagagtta agcaaaatgt agaaactgcg cttcgagcta ccaaagatag
    18181 tactgccggt cgcctattgt ctaaaaagat gaaaactgtc ctctcacaag aaaaacgcta
    18241 cgaaaaggca gctcagtcca tgactcaaaa accacttgaa gaggaacaaa tccaactttt
    18301 cttttcagac atccaaccat taccagcttc taaagtctta gtccaactgg aaaaagaaaa
    18361 tttgtccatt gacgaccgag ttttggttca aaaactacaa ctaactgtcc gtgggcaaga
    18421 aaaaatcggt attatcgggc caaatggtgt tgggaaatca actctgttag ccaaattaaa
    18481 gcaacttctg aatgataaaa gagagatttc ccttggtttt atgccacaag attaccacaa
    18541 aaaactacaa ttggatttat caccaatagc ttatatcagc aaaactgggg aaaaagagga
    18601 acttcagaaa atccactctc acctagccag tctcaatttc agttatccag aaatgcagca
    18661 tcaaattcgc tccttatctg gcggacaaca gggaaaactc ctgcttttgg atctagtcct
    18721 gcgcaaacca aactttctcc tgctggatga acccacacga aacttttctc ccacttctca
    18781 accccaaatc agaaaactct ttgcaaccta tccaggcggt ctcatcactg tttcgcatga
    18841 ccgtcgtttc ttaaaagaag tctgctcgat catctatcgc atgacagaac acggtttgaa
    18901 gctagttaat ttagaagatt tataaatttg caacatagca aaaatccaga gacgacctct
    18961 ggattctttt acatctgttt taaacgttca atccgttctg agataggtgg gtgggtataa
    19021 aagagttttt ggaacccccc acctttcttg ggatcattga tataaagagc actgctagca
    19081 tcatcgacgt ggcgactcat cggtttgcta ttgtccaact tatctagggc attaatcatt
    19141 ccctggggat tgcgagtcag ctcaacacta gatgcatctg ccagaaattc cctctgacga
    19201 gaaatagcga gctgaaccaa ggttgcagcg agaggtgcca gtacaatagc tagtagggaa
    19261 accactagca taatgatttc aagaccattt ccatctcggt catcatcact tcgtctgcga
    19321 cctgctccac cccaccacat catacgacct gccataccag aaagcatggt gatagcacta
    19381 gcaagggcaa ctgcaatagt cgaaatacgg atatcataat tacgaatatg actgacttca
    19441 tgtcccataa cagcttctag ttcttcacga ttcatgatag ctagtagacc tgaagtcgca
    19501 gcaacagccg cattttgagg attagaacct gtcgcaaagg catttaaggc tggatcatca
    19561 atgatgaaaa cacggggcat aggaatctga gcgaccagag ccatatcttc cactacatgg
    19621 tagaggtctg gtgccgtttg ctcatccacc tcacgcgctc cattcatgga catgacaatc
    19681 tctgtcgatt gaaaaatcat agacaaagcg tagataaagc cgataatcag tgcgataacc
    19741 aaaccaccaa gtccagatct tataaagaga taaccaaccg cataaccaac aagagctaag
    19801 agtaggaaaa ataccagcaa caaaatccag gtttttcgtt tattgcttgc aatttgatca
    19861 aacaacatct tagtcaccta aaccgctaaa atcaacttta ggaaccgact tttcctcttc
    19921 aggtgtttga aggaaatctg ccgctttaaa tccaaacatt ccagcgataa tattgctcgg
    19981 gaaagtttct aattttacat tgtagttgct gacaacactg ttatagagtt gacgagagta
    20041 agaaatttta ttttctgtgt ttgtcaactc ctcttgcaat ttaacaaagt tagcactagc
    20101 tttcaaatct ggatagcttt ctgcaactgc aaaaatacct gaaacctgac gagtgagggc
    20161 atcactggct ttcatagctt ctgctggtga agtcgctgcc gccacttggt tacgtagttc
    20221 tgccaccttt tcaagggtag aaccttcata tttggcataa ccttttacag tctcaatcaa
    20281 gttcggcaag aggtcatttc gacgtttcaa ctgaacatca atctgactcc aagcctcctt
    20341 ggtttgcata cgatttttaa ccaaaccgtt atagctaaca atcacaaaaa taacaataag
    20401 agcgataact ccaagaataa tccaagtcat aatataagtc ctttctgctt ttagattagt
    20461 accagtatat caaattttct atgattgtgg taaaataaga tgatactaaa gaaggaaata
    20521 actatgaaac caaaaacatt ttacaacttg cttgccgagc agaatcttcc actttcggac
    20581 cagcaaaaag aacaatttga acgttatttt gagctcttgg tcgagtggaa tgagaagatt
    20641 aatttgacgg cgattacgga caaggaagaa gtttatctca aacattttta cgattcgatt
    20701 gcacccattc ttcaaggttt gattcccaat gaaactatca aacttcttga tatcggggct
    20761 ggggcaggat ttcctagtct accaatgaaa attctctatc cggagttaga tgtgaccatt
    20821 attgattcac tcaataagcg catcaacttc ctacaactct tggctcaaga actggatttg
    20881 aacggagttc atttctacca cggacgtgcc gaagattttg cccaagacaa gaacttccgt
    20941 gctcaatatg attttgtaac agctcgtgcg gttgcccgta tgcaggtcct atctgaattg
    21001 accattccct accttaaggt tggtggaaaa ctattggcac tcaaggccag caatgcgcct
    21061 gaggaattat tagaagctaa gaatgccctc aatctccttt ttagtaaggt cgaagacaat
    21121 ctcagctacg ccctaccgaa tagagatccg cgctatatca cagtggtaga aaagaaaaaa
    21181 gaaacaccaa ataaatatcc acgtaaggct ggtatgccaa ataaacgccc actttaaatt
    21241 ttttagtaaa caaatgttta caaaatcagc ctcgctcttt tatttctagg ctcgggaaaa
    21301 aatgatttac aaaatcattt ttttctgcta tactatccta agcaaaggtt tttaatgtca
    21361 tcccgtgagg tgacgaagac gcagaaatat ttaaaactct ttaaaatcta aattttaaag
    21421 aagtcttact ctgagggcct attgctgtaa aataatgggc tcttttttga tgcccaaaag
    21481 tgaggtttat atgaaacaag aatcaactgt tgatttgtta ctagacgttg accaacgtcc
    21541 ttcggctgga aaaggaattc tccttagttt ccaacacgtt ttcgccatgt ttggtgcgac
    21601 catcttggta ccattgattt tgggaatgcc tgtatctgtt gccctttttg cttcaggtgt
    21661 tggaacactc atctacatgc ttgctactgg ttttaaagtt ccagtttatc taggttcttc
    21721 attcgccttt atcacagcta tgtcactggc tatgaaagaa atgggggggg atgtatctgc
    21781 tgctcaaaca ggggttatct tgactggttt ggtctatgtc cttgttgcta ccagcatccg
    21841 atttgtagga acaaaatgga ttgataaact cttgccacca atcattatcg gtcctatgat
    21901 catcgttatc ggtcttggac ttgcaggttc agctgttacc aatgcaggtc ttgtagcaga
    21961 cggaaattgg aaaaatgctc tggtagccgt tgttactttc ctaattgctg cctttatcaa
    22021 tacaaaagga aaaggcttcc tacgaatcat tccattcctc tttgccatta tcggtggtta
    22081 cctcttcgca ctaactcttg gtttggttga ctttacgcct gtcctagaag ctaactggtt
    22141 tgaaattcct ggtttctact tgccatttag cacaggtggt gcctttaaag agtacaatct
    22201 ttactttggt ccagaagcca tcgctatctt gccaatcgct atcgtaacaa tttctgaaca
    22261 tatcggagac catactgttt tgggtcaaat ctgtggtcgt caattcttaa aagaaccagg
    22321 tcttcaccgt actcttcttg gtgacggtat cgcaacttct gtttctgcct tccttggtgg
    22381 accagccaat acaacttacg gagaaaatac aggggttatc ggtatgactc gtatcgcttc
    22441 tgtctcagtt atccgtaacg ctgccttcat cgcgattgcc ctcagcttcc ttggtaaatt
    22501 cactgccttg atttcaacta ttccaaacgc tgtacttggt ggtatgtcaa tccttctcta
    22561 tggggttatc gccagcaatg gtttgaaagt cttgattaaa gaacgtgttg atttcgctca
    22621 aatgcgaaac ctcatcatcg caagtgctat gttggttctt ggacttggag gagctatcct
    22681 taaacttggt ccagttacac tttcaggtac tgccctttca gccatgacag gaatcatctt
    22741 gaacttgatc ttgccatacg aaaataaaga ctaagagtct aaatacacct aatccactca
    22801 gacagctgag tggatttttc gtataccata ataaaagtgt cttaacaaaa ttattaaaat
    22861 caaaaaacgt ataatatcag atattctaaa accttgatac tgtacgtttt atcatagaaa
    22921 tttttacttt attttctcat caaatgagat ttgcatcaat ctcttgtctt acttgcgttt
    22981 cttcttcgct ttcttcattt tgttagccat acgtttcatg gactgtttca tggcaaattc
    23041 accaatttta cctttcaaac cgccaccaaa catctggctc atatctggca ttcctgctcc
    23101 tccgagagct gataagtcag gcataccgcc ttgtcccatc attccttcaa gggcagacat
    23161 atccattcct cccatatttg gcatattttt aggaaggtta tttggattaa tccccatttg
    23221 cttcatcatt ttattcatat ccccagacat aacaccctgc atgagctgtt tagcctggtt
    23281 aaagtccttg atgaatttat tgacttcgac gaatgtattt ccagaaccag cagcaatacg
    23341 acggcgacgg cttggattta acaaatctgg gttttcacgc tcttcaggtg tcatcgaaga
    23401 cacaatggca cgtttacgag caatctggcg ttcatccacc ttcatgtttt gaagggctgg
    23461 attgttggcc atacctggaa tcatcttgag caagtcttcc atcggcccca tattttgcac
    23521 ctgatctaat tgatcgatga aatcattaaa atcaaaggtg ttttcgcgca tcttctcagc
    23581 catttcaagg gctttttgtt catcgtattc ctgagaagct ttctcaatca aagtgagcat
    23641 atcccccatg ccaaggatac ggctagacat acggtctggg tggaaggttt cgatatctgt
    23701 aattttttca cctgtaccag tgaacttgat tggttttcca gtgatgtgac gaacagacag
    23761 agcagcacca ccacgagtat caccatcaat cttggtaagg atgaccccag tcacttccaa
    23821 ctgagcatta aactcacgcg caacattggc tgcttcctga ccaatcatag catcaacgac
    23881 aagcaagatt tcatttggtt gagccaatac tttcacatca cgaagctcat tcatgaggag
    23941 ctcatcaatc tgcaaacgac ccgcagtatc aatcaagaca tagtcgttat gattagtttg
    24001 ggcttgctcc aaaccttgac gtacaatctc aacagctggt acttctgttc caagtgcaaa
    24061 gacaggcaca tcaatctgtt gtcccaaggt cttaagctgg tcaatggcag ctggacgata
    24121 aatatccgcc gcaatcatca aaggacgagc attttcttct ttcttgagtt tgttggccaa
    24181 tttaccagca aaggttgttt taccagcccc ttgtaaacca accatcatga tgatggttgg
    24241 aatcttaggt gacttgataa tttctgccgt atcagaacct aaaacggctg tcagttcctc
    24301 atcaacgatt ttaataatct gttgcgcagg attaagcgta tcaatgacct catgcccgac
    24361 tgcacgctca cgaactttct tgataaagtc ctttacaaca ggcaaggcaa cgtcggcctc
    24421 gagcaaggcc aagcgaattt ctttggttgc ctcttggaca tcagattcag agatttttcc
    24481 ttttttacgt agatttttaa agacgttctg caaacgttct gttaaacttt caaatgccat
    24541 ttttcttcct cttattctct attatcaatg cttgttaaaa tttctatctg ctcctgcaga
    24601 aagtcatcct tgggatagcg ctccaaaatc tgatcaaaaa tctgactgcg gacaatatag
    24661 tccgagtaca tgtgcaattt catctcataa tcttccagaa tcttttctgt tcgcttgata
    24721 ttgtcataga cagcctgacg actgacaccg aactcctcgg caatttcagc aaggctgtaa
    24781 tcatcagcgt agtagagctc gatataattc atttgcttat ctgtcaaaag cgccgcataa
    24841 aattcaaaga gcgcattcat acgattggtt ttttcgattt ccataacttt tattatacca
    24901 aaaattagcc taatctacca cactaggaag ccgatccaag aagatagata gctaaatttg
    24961 aaaaagacat gagcctagcc ccaagtaatt tccaattgat agctggcaaa gggatgtccc
    25021 tcttgatttt gtagttgata atctagttca atcttttgcc catccacttg ataacgattc
    25081 gtttggataa taaactcctg catacccata ggtgtgggaa tataggctaa actatcacta
    25141 tcctttagaa agcgcataat ggtcttggga ttggaaaatc gactcatcac aagttcttga
    25201 ccatgaaatt taatcactac tttttccttt tcctcattat agaaaagcag gtagctataa
    25261 tctccttttt catgcacttc cacatcataa agctggtcaa tcacttccaa ctgctcatca
    25321 aactgaattg tatttcgcat ccgaatcttc acatcaggcc ctctttcttg tctcttgtcc
    25381 tactatttta ccaaaaagag caggattttg ctataatggt catatgaacg aaaaagtatt
    25441 ccgtgaccct gttcacaact acatccatgt caataatcaa atcatctatg acttgattaa
    25501 tacaaaagaa tttcaacgtt tgcgccggat caaacaactg ggaacttcca gttatacctt
    25561 ccacggtgga gagcatagtc gcttctctca ctgtctagga gtctatgaaa ttgcacgacg
    25621 catcacagag attttcgaag aaaaatatcc tgaggaatgg aatcctgccg agtctctctt
    25681 gaccatgacc gctgctctcc tacacgacct tgggcatggt gcctactccc atacttttga
    25741 aaatctcttt gatacagacc atgaagccat tactcaggag attattcaaa atcctgagac
    25801 agagattcac caagtcctgc tacaagtggc acctgatttc ccagaaaagg tggccagtgt
    25861 cattgaccat acctatccta ataagcaggt cgtgcagctc atttctagcc agattgatgc
    25921 ggaccgcatg gactatctct tgcgtgactc ctattttaca ggagcatcct atggggaatt
    25981 tgacctgact cgaatcctcc gagtcattcg tcctatcgaa aatggtatcg cctttcagcg
    26041 caatggcatg cacgccatcg aagactacgt cctcagtcgc taccagatgt acatgcaggt
    26101 ttatttccac cccgcaacac gcgccatgga agttctccta cagaatcttc tcaaacgcgc
    26161 caaggaactc tatcctgagg acaaggattt ctttgcccga acttctccac acctcctgcc
    26221 tttcttcgaa aaaaatgtga ccttgactga ctatctggct ctggatgatg gcgtgatgaa
    26281 tacctacttc cagctttgga tgaccagtcc tgacaagatt cttgcagatt tatcgcatcg
    26341 ctttgtcaac cgcaaggtct ttaaatccat taccttttca caagaggacc aagatcaact
    26401 tactagcatg agaaaattgg ttgaggatat cggctttgat cccgactact acactgccat
    26461 tcataagaac tttgacctcc cttatgatat ctatcgtccc gaatctgaaa acccacggac
    26521 acagattgag attttacaaa aaaatggaga actggccgaa ctctctagcc tgtctcctat
    26581 cgtccaatcc cttgctggca gtcgccacgg agataatcgc ttttattttc caaaagaaat
    26641 gttggaccaa aacagcatct ttgcaagcat tacccagcaa tttttacact tgattgagaa
    26701 cgatcatttt accccaaata aaaactagaa gaggaatttt atgagtatta aactaattgc
    26761 cgtcgatatt gacggaaccc tagtcaacag ccaaaaggaa atcactcctg aagtcttttc
    26821 tgccatccaa gatgccaaag aagctggtgt caaagtcgtg attgcaactg gccgccccat
    26881 cgcaggtgtt gccaaacttc tggacgactt gcagttgaga gaccaaggtg actatgtggt
    26941 gaccttcaat ggtgcccttg tccaagagac tgatactggc catgagatta tcagcgaatc
    27001 cttgacctat gaggattatc tggatatgga atttctcagt cgcaagcttg gtgttcacat
    27061 gcatgctatt actaaggacg gtatctatac cgccaatcgc aatatcggaa catacactgt
    27121 gcacgaatca accctcgtca gcatgcctat cttctaccgc actcctgaag aaatggctgg
    27181 caaggaaatt gtcaagtgta tgttcatcga tgaaccagaa atcctcgatg ctgcgattga
    27241 aaaaatacca gccgaatttt acgagcacta ctctatcaac aaatctgctc ctttctacct
    27301 cgaactcctt aaaaagaatg tagacaaggg ttcagctatt actcacttag ctgaaaaact
    27361 aggattaacc aaagatgaaa ccatggctat cggagacgaa gaaaatgacc gtgccatgct
    27421 ggaagtcgtt ggcaaccctg tagtcatgga aaacggaaat ccagaaatca aaaaaatcgc
    27481 caaatacatc accaaaacaa atgacgaatc cggcgttgcc catgctattc gtacattggt
    27541 actgtaaaag gaaagaatag ataaaaaccg ctcagctgag cggtttttga tgtctaatta
    27601 ctgccccctg caggaatcga acctgcaact actccttagg agggagttgt tatatccatt
    27661 gaactaaggg agctagataa aaactctgct gaaaagcaga gttttttagt cgaattaacg
    27721 acggatttct ttgatacgag ctgctttacc ttgaagagca cgcaagtagt acaatttcgc
    27781 acgacgtact ttaccgtaac gaacaacttc gattttttca acacgtggag tgtggattgg
    27841 gaagatacgc tcaacaccta caccgttaga gattttacga actgtgtagt tttctgagat
    27901 tccagcacct ttacgtgcga taacaacacc ttcaaaaatc tggatacgtt cacggttacc
    27961 ttcgacaact ttcgcgtgta cacgaacagt gtcaccagga cggaatgatg ggatatctgt
    28021 acgaagttga ccttcagtca agctttggat taatggattc attttattct cctatctttg
    28081 tcaatcttga ggaatcttcc tcagcggata aactgtattt ttgtgcgtcc attacacaca
    28141 agatatagtt taccaaattt ctaaaaaaaa gtaaagaaat ttatagcaaa attcctaaaa
    28201 aaatcgcaac caaaccacct atgtaagtca aagtcaggta agaataaaag accttcttat
    28261 cacttagcag tctttgaagt tcgtcattca aggtcgaaaa agttgttaaa ccgccacaaa
    28321 atcctgttgc tagaatagca tatacttcct tagactctac atgattgtag aatactccaa
    28381 ttaaaaaaca acctaaaaga ttagctatga gcgttccgag tggcaattta gaagcttgat
    28441 tatagcgaga aaagaaatac cgtacgagtg ctccgaaacc acaagcaatt gcaagataga
    28501 cgattaccat ttcttcctcc ctagaaaata agctaagagt aggcctccac cgatgctcaa
    28561 aagcaaatac aggactaaac taagataacg ccctgtatca agcagcttca cagtatcaag
    28621 cattaggctg gaaaaagttg ttaaacctcc gcaaaaaccc gtccccagtg ctaaaatcaa
    28681 gcccttacta gtccccttat agaccagata gcccttgaca agaaaaatca agcagaaaat
    28741 tcccagatag ttgacaaaga gagtgcccca aggaaagtct ggactggctg gtaaccaggt
    28801 ggaaactaga tatcggacaa gtccgcccaa catagcagct agaaaaattc ctagcggata
    28861 aaattgttct tttttcattt gatattttga tcctgataat cacgcgaacg tttgagtatg
    28921 tccgaaaaag tcgcgacaat agtctcctga tagcgcttgt cctctacacg actcctaacc
    28981 ttttcaaaaa taacttcttc tctcttagta tctaaaatcg gtttacctga agctttctta
    29041 taagcaacca ccccctcaac taaatgcatt cgttcttcta acagtttgac aatttggtcg
    29101 tcgatttgat cgatttcttg acgaataata tctaaatcca tacagtctcc tcctttattt
    29161 gaattattgt atcaaaaagc catcaattag gctagtaaaa tcccaactct cgataagaaa
    29221 aatgcactga ttgattacat cagcgcactt ttatgtttat cctactttag cagccaattc
    29281 ttctgcgaat tgttccaagc gttcaatatc ttcttcctcg gcagaaagat caactttaac
    29341 acactctgaa cctttttctg ctcctgttga cacaaagaca cggtcaaagt catcaacagc
    29401 cttacagaat tcatcgtaga aggtatctcc tgagccgacc actccgtaga ttttgccatt
    29461 caagttgaga tctgctaggt cttcgtagaa gtccatcatc tcatctggca attcaccatc
    29521 accataagta taggtcgcaa cgatagcgat gtctgcttcc aagaagtctg aagcgtcaac
    29581 agttgtacat tcatcaacat caacatccaa gcccaagtca cgtaatttgt ctgctacaat
    29641 atctgcaatt tcttcggtat taccggtcat actggcaaat acaatttttg ctaatgccat
    29701 atcgtcctcc tcaatttatc tttctccatt atatcacatc tttttcattt taaaaataaa
    29761 aattcttgtg ctacaatgaa atgagaaaga attgaggtta tttatggaga tttgccaaca
    29821 aattttagaa aaaattaaag aatacgacac cattatcatt catcgtcata tgaaaccaga
    29881 ccctgatgcc ttgggaagtc aggtgggatt gaaagccttg ctggaacatc atttcccaga
    29941 aaaaaccatc aaagccgtcg gttttgatga accaactctt acttggatgg ctgagatgga
    30001 tcttgttgaa gatagagcct accaaggcgc acttgtcatc gtctgtgata cagctaatac
    30061 tgctcgtatc gatgataagc gctatagtca aggtgatttt ctcattaaga ttgaccacca
    30121 tccaaatgat gatgtatacg gtgacctgtc ttgggtcgat actagttcaa gtagcgctag
    30181 cgagatgatt accctatttg cccaaacaac ccaactagcc ttggcagatc gcgatgctga
    30241 gttgctcttt gcaggaattg tcggtgatac aggtcgcttc ctctaccctt ctaccactgc
    30301 acggactctt cgcctggctg cttatttgag agaacataac tttgactttg cggctctcac
    30361 tcgcaaaatg gacactatga gctacaaaat tgctaaactg caaggctaca tctacgacca
    30421 tctggaagtg gatgaaaatg gtgctgctcg cgttatcctg agtcagaaaa tcttgaaaca
    30481 atacaatata accgatgctg aaactgcggc cattgtaggt gcacctggac gcattgacag
    30541 agtgagtctc tggggaattt ttgtcgaaca ggctgatggc cactaccgag ttcgcttacg
    30601 cagtaaagtc catcctatca atgaaattgc caaggagcat gatggtggag gccaccctct
    30661 agcaagtggt gctaattcct atagcctaga agaaaacgaa atcatctacc aaaagttaaa
    30721 aaacttgctt aaaaactgat aaaatacttg ccaaactttt cagaatctga tagactagta
    30781 tagtaacaat ctatggctcg caaagagacc atggcagaaa ggaaatattg caaaatgaaa
    30841 aaagatatcc atccagaata tcgcccagtt gtcttcatgg acacaactac tggttaccaa
    30901 ttccttagcg gttcaacaaa acgctctaac gaaacagttg agttcgaagg cgaaacttac
    30961 ccattgatcc gtgtggaaat ttcatcagac tcacacccat tctacactgg acgtcaaaag
    31021 ttcactcaag cagatggacg cgtggatcgt ttcaacaaaa aatacggtct caaataatga
    31081 taagagaaca gttttggctg ttcttttttg tttcttgaaa tcaactgctg ttttcatgtt
    31141 ccagactcat ctgtaggttc gatttccatg ctactaggca ggaaggaaat agctgtttca
    31201 acacgtccat aatgagctat actattgtca cgaaccacac tttcattgat ggtccaagtg
    31261 gaattcattt tcttaaaagc ttctcggact ttttccaaat ctttggaggc aatggcctgc
    31321 tctaaggttt caaaacgagg acttagacgg tttaccaatt tttccttttc cgcatctagg
    31381 tcaacaggat tttgttcttt ttcaaaagct aatagagctg aggaaatttc ggtgagtttg
    31441 gcttcagtaa tatctccaga tagagctaac ttttccttaa caatcttacc aacctcagaa
    31501 tccttatttt ctactctttc gaagtctgat gccatcttcg taacgagttt ctgggtctca
    31561 gtctgaccac catttttaac cgttttggat gcatctgtga ttttcacaaa gaaaaaactc
    31621 aagctttctt gggcacctgc tggggaaaga attaaaaatg acaaagctaa aactagtaac
    31681 cagcttttag ccttccaata atttctgacc aatgtagcct cctttctcca caccaccaaa
    31741 gcaagtaaaa agtccactac ctatgtgagt gatgtattca ttcatcttat cagtagcacc
    31801 taggttagtt tgaaccttaa caaagttatc aggatccttc tggaaagaaa tgaagagcaa
    31861 tcccgtatca aactgaccag tcttttcatc aatgccatct gagtaagaat aagaacgacg
    31921 taaaagtggc ttatccactt ctttggccaa acaaacatgc gaatcatcag gtaagagact
    31981 caaatccact tcatcaaact catttttctt accaaagggg gcaccgcttt ccttgtaacg
    32041 accaaaggta ttttctcgtt cttcgagact agtgcggtcc caggtctcta aaaacatctg
    32101 aatccgacga actgccatat aagaaccatt ttccatccag tccttactat cagcccagat
    32161 aacgcggtca aagtcttgct ccttggttgg atttgctgtt ccatccttaa aaccaaagag
    32221 gttccacgga gtctccattc gatccccgat agctgcaaat ccagactgac tccaacgaag
    32281 gggcaccgca tttctcccct tacggatgag attgcgaata gcgtgaaagg caatttgctc
    32341 atcatctgca caagcatgaa tcacaatatc tccaccagta tatttttcac gtaattgctc
    32401 cttaggaaat agaggtaaat ccctgaacag tcgagggcgc ttgttttcca agttcatcct
    32461 tttcaagaaa cttgcagata caccaaaagt cagcgtcaaa cgatgaggat tgagcccaac
    32521 tgtctcacca gtatcgctcg gaggaaagag agcattctgt ccatcttttt taaccaattc
    32581 cccctcgacc aacttggcac tataatccgt ccaatccttg aatagctgga taattttatc
    32641 tctatccgtc gtatgcaggt ccaagacaac aaaatagata ttcttttgca tgggcgtact
    32701 atttggtaca tcaagcgaac cttatgaaaa ggtctactgg ttttaaagcg ctttcttttc
    32761 ttcttgaatt gagattttat ttttagacgc gacaatggtt tgagcgtctg ctttcctagg
    32821 atgttctgga cgtgg
//
LOCUS       DBEJKC010000022        32232 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.022, whole genome shotgun sequence.
ACCESSION   DBEJKC010000022 DBEJKC010000000
VERSION     DBEJKC010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32232
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.022"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(228..1316)
                     /locus_tag="ACL3G6_001019"
     CDS             complement(228..1316)
                     /locus_tag="ACL3G6_001019"
                     /EC_number="1.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008888 - glycerol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HGR0545570.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTIKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            complement(1334..2002)
                     /locus_tag="ACL3G6_001020"
     CDS             complement(1334..2002)
                     /locus_tag="ACL3G6_001020"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HGR0545571.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            complement(2021..4459)
                     /locus_tag="ACL3G6_001021"
     CDS             complement(2021..4459)
                     /locus_tag="ACL3G6_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HGR0545572.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIGGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKAALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPVTTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            complement(4610..5908)
                     /locus_tag="ACL3G6_001022"
     CDS             complement(4610..5908)
                     /locus_tag="ACL3G6_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0545573.1"
                     /translation="MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            complement(5925..6233)
                     /locus_tag="ACL3G6_001023"
     CDS             complement(5925..6233)
                     /locus_tag="ACL3G6_001023"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0545574.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            complement(6279..6599)
                     /locus_tag="ACL3G6_001024"
     CDS             complement(6279..6599)
                     /locus_tag="ACL3G6_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0545575.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            complement(6794..7774)
                     /locus_tag="ACL3G6_001025"
     CDS             complement(6794..7774)
                     /locus_tag="ACL3G6_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HGR0545576.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            complement(7787..8533)
                     /locus_tag="ACL3G6_001026"
     CDS             complement(7787..8533)
                     /locus_tag="ACL3G6_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0545577.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            8655..9431
                     /locus_tag="ACL3G6_001027"
     CDS             8655..9431
                     /locus_tag="ACL3G6_001027"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HGR0545578.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            9479..9703
                     /locus_tag="ACL3G6_001028"
                     /pseudo
     CDS             9479..9703
                     /locus_tag="ACL3G6_001028"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            10041..11042
                     /locus_tag="ACL3G6_001029"
                     /pseudo
     CDS             10041..11042
                     /locus_tag="ACL3G6_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085230.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            11055..12146
                     /locus_tag="ACL3G6_001030"
     CDS             11055..12146
                     /locus_tag="ACL3G6_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0545579.1"
                     /translation="MSEIEIINAKKIYHDVSVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIKDGEFYFDDTKINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNLSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     KELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDGYALRMLALDQVEEQAIHV
                     SIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASKIQVSEESTFEEDLQKGNR
                     IRLRINTQKLNIFSADGSQNLIKGVNHGT"
     gene            12136..13781
                     /locus_tag="ACL3G6_001031"
                     /pseudo
     CDS             12136..13781
                     /locus_tag="ACL3G6_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(13884..14576)
                     /locus_tag="ACL3G6_001032"
     CDS             complement(13884..14576)
                     /locus_tag="ACL3G6_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR0545580.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(14820..16157)
                     /locus_tag="ACL3G6_001033"
     CDS             complement(14820..16157)
                     /locus_tag="ACL3G6_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HGR0545581.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            complement(16167..16433)
                     /locus_tag="ACL3G6_001034"
     CDS             complement(16167..16433)
                     /locus_tag="ACL3G6_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HGR0545582.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            complement(16698..17084)
                     /gene="rplQ"
                     /locus_tag="ACL3G6_001035"
     CDS             complement(16698..17084)
                     /gene="rplQ"
                     /locus_tag="ACL3G6_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HGR0545583.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(17096..18031)
                     /locus_tag="ACL3G6_001036"
     CDS             complement(17096..18031)
                     /locus_tag="ACL3G6_001036"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HGR0545584.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            complement(18074..18457)
                     /gene="rpsK"
                     /locus_tag="ACL3G6_001037"
     CDS             complement(18074..18457)
                     /gene="rpsK"
                     /locus_tag="ACL3G6_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HGR0545585.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(18475..18840)
                     /gene="rpsM"
                     /locus_tag="ACL3G6_001038"
     CDS             complement(18475..18840)
                     /gene="rpsM"
                     /locus_tag="ACL3G6_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HGR0545586.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(18858..18974)
                     /gene="rpmJ"
                     /locus_tag="ACL3G6_001039"
     CDS             complement(18858..18974)
                     /gene="rpmJ"
                     /locus_tag="ACL3G6_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HGR0545587.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            complement(18999..19217)
                     /gene="infA"
                     /locus_tag="ACL3G6_001040"
     CDS             complement(18999..19217)
                     /gene="infA"
                     /locus_tag="ACL3G6_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HGR0545588.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(19334..19972)
                     /locus_tag="ACL3G6_001041"
     CDS             complement(19334..19972)
                     /locus_tag="ACL3G6_001041"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HGR0545589.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            complement(20123..21433)
                     /gene="secY"
                     /locus_tag="ACL3G6_001042"
     CDS             complement(20123..21433)
                     /gene="secY"
                     /locus_tag="ACL3G6_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HGR0545590.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            complement(21446..21886)
                     /gene="rplO"
                     /locus_tag="ACL3G6_001043"
     CDS             complement(21446..21886)
                     /gene="rplO"
                     /locus_tag="ACL3G6_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HGR0545591.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(22031..22213)
                     /gene="rpmD"
                     /locus_tag="ACL3G6_001044"
     CDS             complement(22031..22213)
                     /gene="rpmD"
                     /locus_tag="ACL3G6_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HGR0545592.1"
                     /translation="MAQIKITLTKSPIGRIPSQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMITAVSHLVTVEEVN"
     gene            complement(22227..22721)
                     /gene="rpsE"
                     /locus_tag="ACL3G6_001045"
     CDS             complement(22227..22721)
                     /gene="rpsE"
                     /locus_tag="ACL3G6_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HGR0545593.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(22739..23095)
                     /gene="rplR"
                     /locus_tag="ACL3G6_001046"
     CDS             complement(22739..23095)
                     /gene="rplR"
                     /locus_tag="ACL3G6_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HGR0545594.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(23179..23715)
                     /gene="rplF"
                     /locus_tag="ACL3G6_001047"
     CDS             complement(23179..23715)
                     /gene="rplF"
                     /locus_tag="ACL3G6_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HGR0545595.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(23907..24305)
                     /gene="rpsH"
                     /locus_tag="ACL3G6_001048"
     CDS             complement(23907..24305)
                     /gene="rpsH"
                     /locus_tag="ACL3G6_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HGR0545596.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(24590..24859)
                     /gene="rpsN"
                     /locus_tag="ACL3G6_001049"
     CDS             complement(24590..24859)
                     /gene="rpsN"
                     /locus_tag="ACL3G6_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HGR0545597.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(24877..25419)
                     /gene="rplE"
                     /locus_tag="ACL3G6_001050"
     CDS             complement(24877..25419)
                     /gene="rplE"
                     /locus_tag="ACL3G6_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HGR0545598.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(25443..25748)
                     /gene="rplX"
                     /locus_tag="ACL3G6_001051"
     CDS             complement(25443..25748)
                     /gene="rplX"
                     /locus_tag="ACL3G6_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HGR0545599.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(25826..26194)
                     /gene="rplN"
                     /locus_tag="ACL3G6_001052"
     CDS             complement(25826..26194)
                     /gene="rplN"
                     /locus_tag="ACL3G6_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HGR0545600.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(26220..26480)
                     /gene="rpsQ"
                     /locus_tag="ACL3G6_001053"
     CDS             complement(26220..26480)
                     /gene="rpsQ"
                     /locus_tag="ACL3G6_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HGR0545601.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(26505..26711)
                     /gene="rpmC"
                     /locus_tag="ACL3G6_001054"
     CDS             complement(26505..26711)
                     /gene="rpmC"
                     /locus_tag="ACL3G6_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HGR0545602.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            complement(26721..27134)
                     /gene="rplP"
                     /locus_tag="ACL3G6_001055"
     CDS             complement(26721..27134)
                     /gene="rplP"
                     /locus_tag="ACL3G6_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HGR0545603.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(27138..27791)
                     /gene="rpsC"
                     /locus_tag="ACL3G6_001056"
     CDS             complement(27138..27791)
                     /gene="rpsC"
                     /locus_tag="ACL3G6_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HGR0545604.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(27804..28148)
                     /gene="rplV"
                     /locus_tag="ACL3G6_001057"
     CDS             complement(27804..28148)
                     /gene="rplV"
                     /locus_tag="ACL3G6_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HGR0545605.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(28160..28441)
                     /gene="rpsS"
                     /locus_tag="ACL3G6_001058"
     CDS             complement(28160..28441)
                     /gene="rpsS"
                     /locus_tag="ACL3G6_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HGR0545606.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(28545..29378)
                     /gene="rplB"
                     /locus_tag="ACL3G6_001059"
     CDS             complement(28545..29378)
                     /gene="rplB"
                     /locus_tag="ACL3G6_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HGR0545607.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(29396..29692)
                     /locus_tag="ACL3G6_001060"
     CDS             complement(29396..29692)
                     /locus_tag="ACL3G6_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HGR0545608.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(29692..30315)
                     /gene="rplD"
                     /locus_tag="ACL3G6_001061"
     CDS             complement(29692..30315)
                     /gene="rplD"
                     /locus_tag="ACL3G6_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HGR0545609.1"
                     /translation="MANVTLFDQTGKEAGQVVLNDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKLVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(30340..30966)
                     /gene="rplC"
                     /locus_tag="ACL3G6_001062"
     CDS             complement(30340..30966)
                     /gene="rplC"
                     /locus_tag="ACL3G6_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HGR0545610.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(31183..31491)
                     /gene="rpsJ"
                     /locus_tag="ACL3G6_001063"
     CDS             complement(31183..31491)
                     /gene="rpsJ"
                     /locus_tag="ACL3G6_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HGR0545611.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(31757..>32232)
                     /locus_tag="ACL3G6_001064"
     CDS             complement(31757..>32232)
                     /locus_tag="ACL3G6_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGR0545612.1"
                     /translation="NLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDIL
                     ALQAGMDVLTIEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELK
                     RRLARDTTVRNRYASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
BASE COUNT         9639 a         6859 c         5505 g        10229 t
ORIGIN      
        1 taattaatgt attcacaata aatagccgac aacctatgtc gctttttgat ttatgaagaa
       61 cgtatagtag actgaatctg aaatagtacg aaacaattgc taaaacactt atagaaatta
      121 attttacttt cccaatcgat ttgttctcat cttatttcaa tctgctatag aattcaatac
      181 gaggatcaat aaaagactac catttggaaa acagtagtcc ttattgttta ttttgaattt
      241 acataggcat ctacagcgat aatagcttga gcaacatctg aaggcgaaat cttaaacggc
      301 atctgatgaa ttgtctcacc ctccatagtt gcttgtttac caacttttat taaatcatca
      361 tatccaactt gatccaaatg catttctttt atagttgttg gcataccaat ttttttgtaa
      421 aactcaatat acttatcaag ttcttcttta ggtctatttt ccaataatag ttgtactaaa
      481 gttccataag ctactttttc accatgtgtt aaatgatgaa tgtcacctgt caatgcagta
      541 aaaccattat gaattgcatg cgccgcagct aatcctccac tttcaaaacc tagaccactc
      601 aataaagtat tagcttcaac aatattttct aatgctggtg tcaccacttt agcttcacaa
      661 gctgccatag cctgtaaacc atctgcaaac agcgtttctt cacatttctt cgcaattgca
      721 actccagcca atgtttgctg ttgtcccaac atagtttttc catttgcctg cataaccgca
      781 cgcgcctcaa cccaagttgc taaaccatct gcaataccag acgctaataa acgcttaggg
      841 gcttgtgaaa taacttttgt atcaaccaaa actaaatctg gatttttaga ataaaataga
      901 taatgatcaa atgcaccttc atctgtataa ataacagata aagcagatac aggtgcgtcg
      961 gtcgatgcaa ttgttggagc aataataaca ggcttttcaa tcaaatctgc aatagctttt
     1021 gcgctatcaa tcgtctttcc cccaccaaga ccgataatac tatcacaatt ttctttctca
     1081 gccaaggcaa caactcgatt gatttcattg tcagaagctt caccattaaa tagcgccaga
     1141 acaatatgga aaccatacct atgtagataa tcttcaaatc gttttccaac aatatcataa
     1201 accaactgat cgcataatag aatagggcaa tttcccaaat ccaaaattga tttggcattt
     1261 tcaaacaagg cattttcccc ctgaatatat ctagaaggac tagcaaaaat tctcatatgt
     1321 atttcctctc tatctaaatg gaacgactat tttgaataac aaaccaatcg tcagaaaaat
     1381 catcaaccgc cttttggata gatggcatgg cgaaagctga ttcaaaaaca tccgctcctg
     1441 ctgtaacagc atgcgcacct gcagctaaag cattatttac ttgtgctaca tttttaaagg
     1501 atgcagctaa aatcttacta ggagagttct gtctatcaat agcaagagct aattgacgaa
     1561 tgacagaatt tgaatcaatg ttcagatttt ccattctatt ataatatgga gctaggtaat
     1621 ccgctcctgc ttcgatagct aataatccct gaataactgt ataaatagct gttgcagtga
     1681 tatggtagcc ctcttttttt agcgccttta ttgcacgtaa tccagctgga gtaacaggta
     1741 ctttgataaa tatatcatct cctgcttgtc ttcgaatttt atgagcatcc tttaagatgc
     1801 cttcaaaatc ttgagaaatc acctgaacat gaatagaggg tgtagagcca atcaattctc
     1861 ttacatcttt gattcgttca aaaaaattaa tagaaccctc tctttttgca atagtgggat
     1921 ttgaagttac cccagctagc ggcaaaattt cagaccactt tttaatctca tctaaattta
     1981 atgtgtcaag cataaattcc ataaaaagaa cctctttatt ttacaaagta tgctcagtac
     2041 gtcctataat gtcatcttgg gttgccttag aaagaacatt gaagaatgca gagtatcctg
     2101 caacacgaac aattaagtct ctgtgttttt caggatgttt ctgagcgtca atcagcgtct
     2161 ctctggaaac aacattgtat tgaatatggt acccatgtaa acgattaaag aatgttcgta
     2221 acaaagcaat tagttttaat ttatcttctt ctttggctaa cgtttgagga tttactttct
     2281 gatttaagag aaccccacct acgatttcat ctgttggtaa ttttgaaaca gattttaaaa
     2341 cagatgtagg gccgtgttga tccatattat gtgatggtga acaaccctct gctaacggtg
     2401 tacccgcgtt gcgtccatct ggagttgcta atgttccacg tccctgccct acgttggctg
     2461 agatagaaga tgttcctgaa taacgaattc ctccaattgg acctcttcca taacgtgtat
     2521 taggatattt agcaatttca tcaacataaa tgtcataagc agcagtaacc aatttgtcag
     2581 cataatcatc atcattacca tacttaggtg catcatgaat caacatttct tgaatgacct
     2641 taccttcttc tccggcataa tctgtttcca gtgcatgcca aagctgactt gggcttatac
     2701 gttcttcctc aaacaccaat tttttaattg cagctaatga atccgacaaa tttgcaattc
     2761 caacttgcaa tcctgatata taatcatata ctgctccacc ttctttaagg tgttttccac
     2821 gaccaataca atcatcagtc aatgctgaac atagaatatc aggaacttct cgttccaatg
     2881 ataaatcaat agaattttca acaataacac tcattcgtgt caaatatctt agtgttttat
     2941 cccaagcatt ttctaattca gaaaagttct tcatatcctt aaaatgacca aagcttggtg
     3001 caaaccgttt acccgaagcc ggatcaattc catcattcat cgtgataagt agaaccttag
     3061 ggaagttcat ataactcata cctgtgcaac gatagcccca tttccctgga actgccgttt
     3121 caacacatcc aatggcactg taatcataag catcatcttc caatactcct tttgcaataa
     3181 aagaaggaat aataatctca tcattattaa atgcaggcat accaaaacca agtttcatca
     3241 cttcaataca ctcattcatg aaacgagcat ctaaacctgc atggtaacgt acagttagat
     3301 taggttgcgg tagatgggtt tgtgcaactg attttaatac caaataagat aatgggttaa
     3361 cagcatcctt cttatctcga gtctgtccac caattgtaac attttgatat aaaggacttc
     3421 ctgctgaaga aaatgtatgt gattgactgc gaaccttatt aattgtaatt gtcttaatcc
     3481 aaagatttgt cagacgttca acaatgctat cttctgtttc tttaccactt tctaaatcag
     3541 ccttcatata tggatacata tattgatcaa aacggccata tgaaagagag tggccattag
     3601 attcaatttg taaaatacat tgaataaacc aaactgattg aatagcttct gcaaaagtag
     3661 ttaccggttc atatgggact ctagagcaaa tatctgcaat ctcaagtaat tctttcttac
     3721 gtttaggatt tgcattttcg gctaaacttt tagcaagagc aacaaagcgc tttgcatata
     3781 ctttaatagc atcgattacg ataaatatag agtcgtaaaa atgatattta tcaatacttg
     3841 ctggatctgt taaatctaga gctgcttttg ctttacgagc ccgctcttca aaacctctta
     3901 agccaaattg caaaagtttc tgatagttaa ctgctaggtg agcatctcca gaattcatct
     3961 taccttccat accgaagaat cctgtttcca tataaacaga cacttcttca ggtaataagg
     4021 caccagctct agcacgtaaa ttattatttt cccaaaacgg agcaatactt ctaagttgtt
     4081 cttttgtttc ttctgtaata tagaaaacat ctccatcacg cttttcaaaa agatccaact
     4141 cattgagaac aaattctagc gtatattccg gaaaaatagg agcatcttta ttggaagaag
     4201 cttgatttcc cccaatcata gattcttctt caatatagat agtcatattt tccaaaattt
     4261 ctttcagcat atatgcacgt tttaggacat taggttgttc cttgtatcgt tcataggcgc
     4321 gtgttgctag aactgctctc tcagcatcaa tataaggttt tttatttaaa acatcttctc
     4381 gatatttgtt catcctttca gtaaggctgc caaaatattc tgtcttgatt gttgttcttg
     4441 ctacttctgt atttaccatc gtaaccacct ttctttcgaa aatattttta tttctttcga
     4501 aaatataata ccgattttta tagaaatttt caagctttta actagaaaaa ttttaactct
     4561 ctaattttta gcacaaatgt gtgagtttaa cagtaacaca caaatacctc taagattgtt
     4621 tgatttcatt ttggtaagct aaacgatcct gtactttaaa gaatggaaaa taaaccaatg
     4681 tagacatcgc taatatcacc agctgagtaa taactccttg ccatccaccc accaaaaatc
     4741 ctgataaaat agctggtgta ctccaaggca atgttacccc tgagaatggc tgcatgaaac
     4801 ctgttgcaat agctccatat actatcacag ctgcaagtac aggaacaaga atgaaaggta
     4861 caaacataac tggattcatg acaatcggaa atccaaatac aactggctca tttacgttaa
     4921 atattgctgg aaaagcggca acttttccta aggcttggta ttgttttgat tttgctgcaa
     4981 aaagcatggc aactacaaga ccaaacgtaa tccctgaacc tgatagaatt aaaaatgaat
     5041 ctaaaaattg ttgagtaaca atatgtgcac cattttctaa tgatagatta ccagaggcta
     5101 acatagcttt attagcatca agattagata aaagcagagc tgtcactact ccatttacta
     5161 ccgattgtcc atgaacacca aaccaccaca aaaatgatat aaagaatgca attccaatag
     5221 caccatacaa agatccagtt aaaccttgca atggaacttg aatagcagaa taaatcattt
     5281 ctatgaatgt tccgccatta gtcaatgact tcgctaaaat atatacaatc atagaaagta
     5341 agaaaattac aaatgctgga atcattgctt caaactgttt ggcaatagct tgtggaactt
     5401 gttctggcat cttaataaca atttttctct ttataaagaa ggtataaata cttcctacta
     5461 ccaaacctat aatgatagca ccgataattc cttgacctcc aaaccaaact ttactaatag
     5521 catccccaat tgcctcacct tgtttaggga tataagatga tcttagcaaa ataaagaatg
     5581 cagatacaga tagaactcca gctggtaaag cctctactcc gctattctta gcataagaat
     5641 aggcaattga aaaacaagaa attagaccca taatagcaaa agttcctgaa tatacttgca
     5701 taaacggctc tgtccaatta gctccaaaaa cactagcaat gctcttattt aatccttcga
     5761 acggcaattg tcccataatc aagaataaac taccaactac tgtcaatggc aaaattgcta
     5821 acatcccatc ttttagagct ataatgccac gcatattcac aaacttcatc atcggtgcaa
     5881 tgattttctg aacatccatc tttgccataa taaatctcct tttcttaccc actaatcaaa
     5941 gatagggcca aatctaatac ttttttccca tctaacatac catagtccat catcggaata
     6001 acagctatcg gaacatcaca cttatcacaa atttcttttg atttatctaa tgtataagca
     6061 acttgtggac ccaatagtgc aacatctata tttggcgcat aatccgctaa tttagactga
     6121 gaaaacgcct ctatttctgc ctcaactcca ctagcttgcg ctgcaatttt catattattt
     6181 acaagcatac cagtagaaaa acctgctgca caaaacaaac caatcttcac cattatgttt
     6241 tcctcctcta tgttaataac aatgataata ctctagtatt attttttatg aagttctttt
     6301 ctcaaactaa taatttcttt gattaaatta atctccgtca tactagtcat gagatgatct
     6361 tgtgaatgaa caaagagagc tgtaatttct gtctttgtac cagacgcttc ctgtgccaag
     6421 aattttgttt gtagattatg agcttctaat aaggctgcat cagctaactg gatttcttct
     6481 tcacatcgtt cacatgtacc attttttatg taatctaacg ctttataaat atgttgtttc
     6541 gcatcgccag catataaaat taaacccatg ataatttgat ctggaacaat aatttccata
     6601 aattcctcct catttcacta tgtaaaaagc ttttttcatt tgaaatttta aaattttctt
     6661 ttgtaactat agaatacaac tacataataa agttgtcaat ccaaaaacaa cagataaact
     6721 atttttgttt atataagcac aaatgtgcaa tcaactaaaa agaaaaacga taaactgaat
     6781 cagtctatca ttttcactca cctagaatct ctctaaaagt caaatcccca tcttcttcca
     6841 aaacttttaa aattgtattt ttgtctgtaa tcaaatgatt tactaaatta gcacgcaaga
     6901 cagaaagaat cgaagatact ttcgtatcac cgtaagcaac agctaaactt tgaggaatat
     6961 tttttaaatc ttccaaagag attgctatcg ttctttcctg taagttttca tagacttctt
     7021 taccttttga atcaaaaaat cgacaacaaa tttctcctac agttttaact ttggtcaatt
     7081 ctttaaagtc atcctctgta agcatgtcta accattgatg ttttccttta ttgctaaaat
     7141 caccaattcc gactacagct atatctaaat ctttccaact atttttcaaa ttttcaaaat
     7201 atcttgattg caaaatacca tctgctaaca atttattttc ttgcacaatc gttgcattca
     7261 taaatgtaca ctctccatga aattttctag acatttcata aatcagtgta ttcacatggt
     7321 atttagcgtg tatgtgacta ggaccacctg ctagaggata gaagtgaaca tttcggacac
     7381 ttttactgtg aattaaatct actaaattac ttaaactttt cccccaagaa aagccaattt
     7441 tcatattatc atcaattaaa ttcctaagga cacctgctgc aacttgagaa attctttcag
     7501 ataaaattgt tggattatca tcaaattcat ttggaataat ttctaaactt tccagaccat
     7561 atttttcttt tacataattt tccaacttaa acatatttgt atcaaaattc tctatttcaa
     7621 ttttaacaat tcctgcattc cttgcttctg ttaacattct actaatagag gttctataaa
     7681 ttcctaattt tgctgctatt tgtgactgat ttaagttttc aatataatac agataagcaa
     7741 ttttagagag cagtttattc ctatcttgat tcatacactt aacctcttac gaaactacct
     7801 taaccattat cccagcattt tctaatgtag ctatattttg tttagaaagt ttttcgtctg
     7861 ttattacttc atagacttga cttaaagcaa atcttcttac tgtacccctt ttatcaaatt
     7921 tacttgagtc agttagtaca atgactttat ccgacgctgc tgaaatatat tgaactacct
     7981 cactgcgcat taaatctttt cctgtaaagc ccatctcttt atcgtaacca tctgtcccaa
     8041 caaaagcttg atgcacatga aaagtctgta tcatttcttt taataaaggt cccacagtaa
     8101 cctgtgaatc cttctgaaac tctccaccaa gaacaataat acgacatgaa tcataagctc
     8161 tcacaaaatt tgctataaaa aatgaatttg ttacaatcgt aacatttctt ttttgcttgc
     8221 aaatttcctc agcaagtaaa gcacaggtcg atccagattc tatcattatt gtttcattat
     8281 ctgacaccaa ttttactgct tcctgaacaa tttttctctt aatttcataa ttaattgaca
     8341 aacgtacatt taagtcatct ccactattta atacagcata tccatgctct ctgtgtaata
     8401 aaccttttga ctctaattta tctaaatctt ttctaatcgt tactttcgat acatttaatt
     8461 tttccgataa tgtattaacg tcgatctttt catattctga tactaattta ataatttgtt
     8521 ccaatctttt cattttacac ctccgtttta ttctaccaaa ataaaaagca aaaaacaaca
     8581 aatcaacctt tcgttcgtaa ttgtttttct ttcgtttttg tgataggata gacttatgaa
     8641 gaggaggaac tcttatggaa atatctaaag gaattatttt taatattcaa cacttttcaa
     8701 ttcatgacgg cccgggtatt cgtacaactg tttttttaaa aggatgtcct ctgcgctgtc
     8761 catggtgttc taatcctgaa tctcaaagaa tgaaacctga aaaaatgaaa gatgctcaac
     8821 gagagaaatt caccttagtc ggtgaagaaa agactgtaga agaaattatt acagaggtat
     8881 taaaagacaa agaattttac gaagaatccg gtggaggttt aactttatca ggaggtgaaa
     8941 tatttgctca gtttgaattt gctaaagcca tcttaaaatc agctaaagaa catcacatac
     9001 acactgccat tgaaactact gcctttgttg atcatgaaaa atttatcgat ttaattcaat
     9061 atgtggattt tatctacaca gacctaaaac attataattc tataaaacat aaaaaagtga
     9121 ctggggtttt taatcaaatg attattaaaa acattcatta tgctttttct caaaataaaa
     9181 ctatcgtttt aagaatccca gttattccta attttaacaa tagtttagag gatgcagaaa
     9241 aattcgctac tctatttaac tcattaaata tcgaccaagt tcaactactc ccttttcatc
     9301 aatttggtga aaacaaatat cgtttattaa atcggaaata tgaaatggat ggagtcaacg
     9361 cacttcatcc tgaagatctt attgattatc aaaaggtatt tctgaaccac catattaatt
     9421 gttatttcta gttcatttcc ttgaaatgct ctagctattt gcagataaca agcatctata
     9481 taaggttatc aaagaagact tccccatgac tctaaatgaa tatatcttac aatatcgcct
     9541 gaaacaagct atagataaga tggctgaatc tcccaactcc cctttaagcg ctatctctga
     9601 ccaagttgga ttttcagact ataaatattt tgccaaagta tttaaaaagt atctccatat
     9661 ttccccaaag aaattgaaat cactcggaag aatagtaaaa taggctattc ttctttttgt
     9721 agagaatttt actctaatat agtgaattga aataagatgt gaacatctct atcaggaaag
     9781 tcaaattaat ttatagaaat attttagcag tcaaagtgta ctgttataga ttcaatacac
     9841 tatagaatag aattgtaggt tttaaaaacg cttacattgt tttaaaataa acttaaataa
     9901 cacaacggag atatcccatc atgaaaaaga aatggatgta ttatgctgct tgttcttcta
     9961 atgaatctgc cgatgacagt tcatctgata aaggagacgg tggttcgcta gtcgtttatt
    10021 gaccaaactc agaggactta attggagcaa ctattcctgc ctttgaagaa aaatatggta
    10081 tcaaagtaga actgattcaa gctggtactg gagaactttt caaaaaacta gagtcagaaa
    10141 aagaagttcc tgtagctgat gttatctttg gtggttctta tacacaatat gctacccacg
    10201 gagaactctt tgaaaactat acttcaaaag aaaatgataa tgttatcaaa gaatatcaaa
    10261 acacaactgg cttctctact ccttatacac tagatggtag tgttttaatc gtccaccctg
    10321 atttaactaa aggcatgaac atcgaaggat atagcgacct tctcaaacct gaactaaaag
    10381 gaaaaatcgc aactgctgac ccagcaaact cttctagcgc ctttgctcaa ttaacaaata
    10441 tgctacaagc tcaaggtggt tacaaagatg ataaggcttg gtcttatgta aaagatcttt
    10501 tcacacttat tgatggtata gtaaaatgaa ataagaacag gacaaattaa tcaggacagt
    10561 caaatcgatt tctaacaatg ttttagaagt agatgtgtac tattctagtt tcaatatact
    10621 ataaaatcgg tttaagttca tctggtgtct ataaagcagt cgctgatgga gaaatgactg
    10681 ttggtctctc ttatgaagat ccagcagtta aactcttaaa tgacggagct aacattaagg
    10741 tagtctatcc aaaagaagga accgtcttcc tacctgctag tgctgctatc gttaaaaaat
    10801 ctaaaaatat ggaaaatgcc aagaaattta tcgattttat tatctctcaa gaagtacaag
    10861 atacacttgg tacaaccact actaaccgtc ctgttcgtaa aaatgctaaa acaagcgaaa
    10921 acatgaaacc aattgacaaa atcaaaacac tcactgaaga ttatgattat gtcatcaaga
    10981 ataaatcaga tatcgttaag aaatacaacg aagtctttac agatatccaa tctaaacagt
    11041 aaaagaggtt cactatgagt gagatcgaaa ttattaacgc caaaaaaatc taccacgatg
    11101 tctctgttat tgagaatttg aacattacaa ttccaaaagg aagtctcttt acccttcttg
    11161 gagcttcagg atgtgggaaa acgacccttc ttcgtatgat tgcaggtttc aacagtatca
    11221 aagatggaga attttacttc gatgatacaa aaatcaataa tatggaaccc agcaaacgca
    11281 atatcgggat ggttttccaa aactacgcta ttttcccaca tttgactgtc cgagacaacg
    11341 ttgcttttgg tcttatgcaa aagaaggttc caaaagaaga attgattcaa cagaccaaca
    11401 agtatcttga actcatgcaa attgctcaat atgcggatcg aaagcccgat aaactcagtg
    11461 gtggacaaca acaacgtgtc accttggcat gcgccttagc ggttaatcta agtgttctcc
    11521 tcatggacga gccacttagt aatctggagg ccaaacttcg cttggatatg cgtcaagcca
    11581 tccgagaaat ccaacacgaa gtgggaatta caactgttta tgtaacccac gaccaagaag
    11641 aagccatggc tatttcagac caaattgctg ttatgaaaga tggggtgatc caacaaatcg
    11701 gccgaccaaa agaactctat cataaaccag ctaatgagtt tgtggcaacc tttatcggac
    11761 gcacaaatat tatccctgcc aatcttgaaa aacggagcga cggcgcttat atcgtctttt
    11821 cagatggcta tgcccttcga atgctagctc ttgatcaggt tgaggagcaa gctattcatg
    11881 taagcattcg tcccgaagag tttatcaaag atgaatctgg agatattgaa ggaactatta
    11941 gcgatagcgt ctatcttgga ctaaatacgg agtatttcat tgagacaggt tttgcctcaa
    12001 aaattcaagt tagtgaagaa tcaacttttg aagaagatct acaaaaaggc aatcgtattc
    12061 gtctacgaat caatacgcaa aaattaaaca tcttttctgc agatggttcc caaaacctga
    12121 taaaaggagt caaccatgga acgtaaaaaa ctaaatattt ggacagcctc ctctttcttc
    12181 atctttctta cctatcttgt ctttctcgtt tatcctatcg ttaccgtgct caagtaagca
    12241 cttatacatg aaggacaatt ctcactagct aattttgtca ctttctttag taaagtctac
    12301 tactctgaga cactagtcaa cagtttcaag gtttccatta ccgctactgt cacttcctta
    12361 gttgtaggaa ccctattagc ttatctcttc tctatgtatg acttcaaggg ggagaaattt
    12421 ctacaaatat tgattatcat tgcttccatg tcagctcctt tcgtaggagc ctactcctgg
    12481 gttctcttgc taggacgaaa tggggtcatc actaaatttt tgacaaatgc ccttcatctt
    12541 ccagctatcg atatttatgg attcaaagga attgtacttg tctttacact gcaactattc
    12601 ccactggtat ttctatatgt tgctggaaca atgaacagta ttgacaattc tctacttgaa
    12661 gcagctgaaa gcatggggtc cttcggattt aagcgtatcg taacggttgt tttacctctc
    12721 ctagttccaa ccttactagc agttccttgc ttgtatttat gagagcattc tcagactttg
    12781 gaacgcctat gttgattggc gaaggatatc ggactttccc tgtcctgatt tatacccaat
    12841 ttattagcga ggttggagga aattctgctt ttgcaattat ggcgattatc attgccttgg
    12901 cgattttcct tatccaaaaa cacattgcaa accgctacag tttcagcatg aatctgctcc
    12961 atccaattga gcctaaaaaa actacaaaag gaaaaatagc tgccatttat gcaacagtct
    13021 acggaattat ctttatctct gttttacctc aaatctactt aatttatacc tctttcctaa
    13081 aaacatcagg tatggtatct gttaaaggtt attctccaaa cagttacaag gtagctttcc
    13141 atcgtatggg atctgctatt ttcaatacca ttcgtatccc tttgattgcc ttagttctag
    13201 ttgttctatt tgcgacattt atctcctacc tagccgttag aaaacggaat ttgtttacaa
    13261 acttaattga cagcctcagt atggtacctt atattgtacc aggaaccgtt ctagggattg
    13321 ccttcatttc ttccttcaat actggtctat ttggaagtgg atttcttatg attacaggga
    13381 ctgctttcat cttgattatg tctctatctg tcagaagatt accttatact attcgctcat
    13441 ctgttgctag cttacaacaa atagcaccaa gtattgaaga agctgctgaa agcttaggaa
    13501 gtagtcgtct caataccttt gctaagatta caactccaat gatgctatct ggtatcattt
    13561 ctggagccat cttatcttgg gtcacaatga tttcaaaact ctctacttct atcctcctct
    13621 acaatgtcaa aacaagaaca atgactgtag ctatttatac agaggttctc agaggaaatt
    13681 acggtgtagc cgcagccttg tcaactatcc tgactgttct aacagtaggt tccttgctct
    13741 tgtttatgaa aatctctaaa agcaatagca ttacacttta gttttccaca tcaaaaacag
    13801 ccgaaaggag taccctcggc tgttttttct tatcttgata ttcttatcaa atccctagct
    13861 catggcaagc aagtctagac tgattaaata gagccttctt ccatcttctc acgtcctagc
    13921 tctcggtaac tacggtcacc gacaacttca accctaaact gaccgtcctc atattcaaga
    13981 atcgtcacgc taccattatc tagaccatgc ggatgcatgc cattaatcag ataaacaatg
    14041 gttccaatag tcattccatg gctgacaaca agggcgttac ctccaccttg atcttccatt
    14101 tcttttgcaa tcatttcaaa gccttccttg attcggccac tgagtttttc ccagccttca
    14161 gcccaaccag ctgtatcgac ctctaccaag ccctcagcca gttcagcata agacaattgg
    14221 tgaacgtggt ccacattaaa gatacgagga ataatgccca tgaaaagatc gccatcatag
    14281 gctccatcaa aactaccgaa acaccattct ctgatacgct tgtccatgcg ataagggatt
    14341 ttcccctgca agccaagttc ttcaaggata attcccatgg tctgaatggt acgaccagaa
    14401 tcactcgaat aagcgcgctc aaactgtaga tcagattctc gcaaaccgat tcctaactct
    14461 tgaatccctc gttcaccttc agcagttaag ggagtatcgc tccaaccttg cgcgcgacca
    14521 atcgtgttaa acatggtctt gccatgacgt accaaataca atcgtacttt taccattttc
    14581 cgtcctccgt ttgcttctat tatatcatga atgataaaat aaaagccacc catacaggcg
    14641 acttttgaag gagattatta tgaaaaagtt taggagttca ttaaataaag atattagatg
    14701 aaaatcaaat tcaaactaat tcagtgttat ctgtttcaaa taatattagg aggtctttat
    14761 ttaatgatta tagtatacac gtctaatctt aaatagaact taaaatttct cctattttct
    14821 taatttttaa aactatgaat tggtgctggg atttgtccac cgcgagagat gaagtcgaca
    14881 gacgaagccc cattaacctt cataacaggt gcagttccta atagaccacc aaactcaatc
    14941 atatcgcctt ctcttccttt gggaatgata cgaacagctg ttgttttcat gttgataaca
    15001 ccgattgctg cttcatccgc aatcatagcc gcaatggttt cagcaggcgt atcttctggg
    15061 atggcaatca tatccaatcc aacagaacag atagccgtca tagcttctag tttttctaaa
    15121 ttaagagagc cattttgcac tgcagcaatc attccttcat cctcagaaac agggataaag
    15181 gcaccagata aaccaccgac ttggttgcag gccatcactc cacccttttt aacttggtcg
    15241 ttcaagaggg ccaaggcagc cgtcgttcca tgcgtgccaa ctgtttctag ccccatttcc
    15301 tcaaggacac gtgccacaga gtctccaacc gcaggggttg gtgccaaact caagtccaca
    15361 ataccaaact ccacacccag tctctcactg gccatttgac caaccaattg accgatacga
    15421 gtgattttaa aggcagtttt cttaactgtt tcggctacta catcaaagct ctgtccacga
    15481 actttttcca aagcacgttt cacaacacca ggaccagaaa ctccgacatt gatgataaca
    15541 tctgcttccc caacaccatg aaaggcaccc gccataaatg gattgtcctc aacagcatta
    15601 gcgaatacaa ccaacttggc cactcccata tctgaaagat ttgctgtttc cttgataatt
    15661 cgtcccatat ctgccacagc cgtcatatta ataccagact tggttgagcc gatattgact
    15721 gacgagcaga ccttatccgt ctcagccaaa gcgcgaggaa tggaattgat gagaatctca
    15781 tctccctttt gataaccttt ttgtactaag gcagaaaaac caccaataaa gtccacacca
    15841 atctctttcg cagccttatc aagcgctttt gccagaacca cgtagtccgt cgcatctgtc
    15901 gctgccccaa tcagagaaat aggtgtcacc gatacacgct tattaacgat aggaattccc
    15961 aactcagccg caatttcatc accaacagct actaaattag ccgcctttgt cgtaattttt
    16021 tgatagattt tctccgcagc acgattgata tttggatcga tacagtccaa aagagaaatc
    16081 cccatggtaa tggttctaat atcgaagttt tgctcctcaa tcatggcgat ggtttcagta
    16141 acttgtctaa tatccatgat gacctcctag atattataca tagcttcgaa aatcgctgca
    16201 ctctgaatat tgatttttac attcaaagtt tgcccaaaag cttcaaattc attacgaaga
    16261 taggtaaaat cttgcttttc atcactagat acaacagcca tcatcgtaaa atattcatcc
    16321 aatacagttt gagagatatc gtcaatattc aatcctaatt ctgcaatttt accagaaaca
    16381 cctgcaacaa ttccagattt atctttacca acaacagtta taatcgcttt cataagtaaa
    16441 ctccaattct tcttaaaata agaaacctta acattaaaca ggattctttt caaatagtat
    16501 agcataattc taacgaaaat actcaaaaac gcctgcttac gaagttgttc ttaagaaaaa
    16561 aacaatttcg taaacaagcg tctactatcc caacttatga tgagtgttcc cgctaggacc
    16621 gaaatcctag cggtagacca gagctagact aagagcacaa gactccatca tcataacact
    16681 caacaaaatt gatgatttta tactaattcg atgatcgcca ttggcgctgc atcaccacga
    16741 cgtggttcag ttttaaggat acgagtgtat ccaccgttac gttcagcata acgaggtgcg
    16801 atttctgaga acaatttttg aagtgctgta gtagaagtgt acttatcagt tgcttcatca
    16861 tagttttcag atgcgatttc attacgtacg aaagcagctg cttgacgacg tgcatgcaaa
    16921 tcaccacgtt tacctagagt aatcattttt tcaacagttt tacggatttc tttagcacga
    16981 gcttcagttg tcacgattga ttcgttgatc aaaaggtcag ttgtcaaatc gcgaagcatt
    17041 gctttacgtt gtgagctagt gcgtcctagt ttacggtaag ccatgtattc ctcctttatt
    17101 tatcttttaa tccaagaccc aaatcaatga gtttgagttt cacttcttcc aaactcttgc
    17161 gtccaagatt tcgtactttc atcatctctg cttcagattt ttctgtcaaa tcatgcacag
    17221 tattgatacc ggcacgtttt aaacagttgt atgaacgcac agacaagtcc agttcctcaa
    17281 tcgtacgatc taaaatacgg tcgtcagatt cagtatcagc ttctttcatc acttcagttg
    17341 acttagcaat ctcagtaaga tttgtaaaca aatcaagatg ttctgtcaaa atacgtgctg
    17401 aaagccctaa agcatcttct ggaataattg ttccatttgt caagatttca agggttaatt
    17461 tgtcgaaacc atcattgcta cctacacgag caggttccac ttgatagttg acttttgtaa
    17521 ctggtgtata aatagaatct acagcaagtg ttccaactgg tgcattatcc tttttatttt
    17581 catcagcagg tacatatcca cgaccactgt taacagtcat agtcgctttt agagaagaac
    17641 cttcaccgat tgtaaagaga taatgatctg gatttacaat ttcaatatcg ctatctgtca
    17701 aaatgtcacc agctgttact tcagcaggac cttcaacatc cagttcgatg attttttcgt
    17761 cttcaacgta cgatttcact gcaattcctt taatgttcag aatgatttgc atcacgtctt
    17821 cacgaacacc tggaactgtg tcaaactcat gtaacacacc atcaatgttg atagatgtca
    17881 cagctgctcc tggtagagaa gctagaagta cacgacgaag agagttacca agagttgtac
    17941 cgtagccacg ttcaagtggt tcgattacaa acttgccata atctttattt tcatcaattt
    18001 ttgttatatt tggtttttca aactcgatca tttagttact ccctcttaaa cgaaaagcag
    18061 tgtaatgcga tgattataca cggcgacgtt ttggaggacg agcaccattg tgtggcactg
    18121 gagtcacatc acgaattgct gttacttcaa gaccagcggc agcaagcgca cgaatagctg
    18181 actcacgacc agaacctgga ccttttacag taacttcaac tgatttaaga ccgtgttctt
    18241 gtgcagattt agcagcagct tcagaagcca tttgagcagc gaatggtgta gatttacgag
    18301 aacctttgaa accaagagca ccagctgatg accaagcaat tgcattacca tgcacatcag
    18361 taatcataac aatagtgtta ttaaatgtag cgtgaatatg agcaatacca gattcgatat
    18421 tctttttcac acgacgttta cgtgttggtt tagccaagac ttttacctcc tatattattt
    18481 tttcttacca gcaatcgcaa cagctttacc tttacgagtg cgagcgttgt ttttagtatt
    18541 ttgtccacgg acaggaagtc cacgacggtg acggatacca cggtatgaac cgatttccat
    18601 caaacgtttg atgttcaagt ttacttcacg acgaaggtca ccttcaactt tgattgcatc
    18661 cacttcacga cggatagcat cttcttgatc tgatgtaaga tcacgtacac gaacatcttc
    18721 tgagattcca gcagcagcca aaattttctt agatgttgca agtccgatac cataaacata
    18781 agtcaatgag attactacgc gtttgtcatt tggaatatca actccagcaa tacgagccat
    18841 gttttctcct ttctatctta tccttgacgt tgtttgtgtt ttggatttgc tgggcaaatt
    18901 accataacac gaccattacg acgaataact ttacagtatt cgcaaattgg tttgaccgat
    18961 ggtcttactt tcatttctta tccctccaag tttttcgatt atttaaagcg gtaagtgata
    19021 cgtccacgtg tcaagtcata tggactcatt tcgacagtaa cacgatctcc cgctaaaata
    19081 cgaatatagt ttttacgaat tttaccagaa actgttgcta aaatctgatg tccattttca
    19141 agttcaaccg taaacattgc attcggcatt gtatcaacta ctttgccttc aacttcaatc
    19201 acatcgtctt ttgccacgca aaagcacctc cataaatttc gatttgatgc ctctagacac
    19261 agagacaaca attataagtc agactatttc agtataacat ttgtagcgga tttttgcaag
    19321 tgtgaaaaac gctttatttc aaatttgtca atactttttc aatatctgag aagacatcat
    19381 tgatatcttg attaccttcg atgtcatgaa ccaaaccttt ggcacggtag tgagcaatga
    19441 ttggttctcc ttgagcaata ttaacatcca aacgacgttt tactgtctca ggcttatcat
    19501 cttcacgttg gtagtaatct tcttctttat agtcaactgg tgggttaaag accttgtgga
    19561 aagtttctcc agttacgcgg tggatgatac ggccactcaa acgttccaag aggctgtcag
    19621 ggttcacttc aatattgata ataccttcta gttcaatgcc aagttcagcc aatgttttgt
    19681 ccaaggcatg agcttgttca attgtacgtg ggtaaccatc caataagaat cctgtttctt
    19741 taatatcatc ttgtgaaagg cgttctttta cgattccatt tgtaacttcg tcaggaacca
    19801 attcaccctt gtcaatatat gacttagcaa gaacacccat ttcagtttga tttgccattg
    19861 cagcgcggaa catatcacct gttgagatat gtgcaacatg gaattgttct acgatttttg
    19921 ctgcttgagt tcccttacct gcaccaggta agcccataat caaaagattc atgatttgat
    19981 ctccttattt tatttttaaa tagaagcaaa aagtcttttc acccctattt aaaaacaaaa
    20041 tagaagaggg gagatccaac tcttacaaat gtcagagttt aaacctccac tccctcagta
    20101 tttactgatt cagtaaatac ttttattctg ttctgtccat gaaaccaaca tacttacgtt
    20161 tcaataggta accttccaat tgcttgattc cttcgatacc tgtagagata atgatcaaga
    20221 gacttgttcc accaaaggca acaacatcag aaagaccaaa tacatcttta gctgcaatcg
    20281 gtaaaatgga aatcacacca agaaagaggg aaccaacagt tgcaagacga cgaagaagtt
    20341 tagacatata ttcttctgta cctttaccag gacgaactcc atggatatag gcaccactct
    20401 tttgtaggct ctctgctgct ttttcaggat taatctgtac aaacgtatag aagaatgtaa
    20461 agagaataat caacaaagca tacatggcaa taccagttgg agaagtagtt gccaacatct
    20521 cttgtgctac ccttacccaa gcccaatcat gacctgtggc actcaaaaac tgaagaatag
    20581 ccgcaggcgc tgcagtaatc gaactggcaa agataacagg gataactcca gcagggttta
    20641 cctttaacgg aaggtaagag ctagatggag caccttgtgc aaccttagta tattggattg
    20701 gaattttgta ttctgcttgt tgaacataag ttgtaaagta aataatcaac aatacagtaa
    20761 taatcaaaat gattacgaaa atgatagatg aagtgatacg gctacttggg acgttcacaa
    20821 agtagtccac atagatgccc tgaatcatct ctggaattga ggaaacaatc ccggcaaaga
    20881 taatcatgga aacaccgttt ccgtatccct tatctgtaat ttgctcaccc aaccaagtga
    20941 caatcatact accagctgtt aagatgatac caatcgtcag aaaaacttgt ggagttaaag
    21001 cagttttaat caattgagct ccagccaagg tattaaaacc agctgtaatc ccgatagatt
    21061 gcacaaaagc gagaactaga gcaatataac gagtagcttg attcaatttt cttcgaccta
    21121 cttccccttg tttaccccac tctacaaact tgggtaaaat atccatttgc aagagttgga
    21181 caacaataga agcggtgata tagggactaa ctcctagggc aaaaatcgaa aagtttttta
    21241 gggcattccc cgacaccaag ctcaacatgt ttaagaagga taatccactt aaagcattca
    21301 agctattggc attcacacca ggaactgtaa tgctagttcc gatacgaaag accaaaacga
    21361 taaaaattgt aaataaaatt tttgatcgaa cctgcttgac tttaagagct tctcttaata
    21421 atttaaaaaa cataggtcac ctctcttaga tgacttctac tgaaccacct ttagcagtga
    21481 tagcttcttc agctgattta gagaatttag ctgctttcac agtcaatttc ttagtcaact
    21541 caccgttacc aagaatttta atacctgact tttcagcttt aacaattcct gcttcgataa
    21601 gaacaactgg agttacttca gcaccatctt caaagacgtt caattggtca aggttcacaa
    21661 ttgcgtattc tttagcgttg atgttagtga atccacgttt tggaagacga cggaacaatg
    21721 gagtttgtcc accttcaaaa ccaaggcgaa ctccgccacc gctacgagct ttttgacctt
    21781 tttgaccacg accagatgtt ttaccgttac ctgatgaagt accacgacca acgcggttac
    21841 gtactttacg agaaccttct gcaggtttca attcatgaag tttcattttt attttctcct
    21901 cttttgtaaa atgctagcgc cgataaggga gaaaaggttg tctcccccat caactcgcct
    21961 atacgatgtc atcatagatg actatatcta gttttagggg atggtacagt gcacatcccc
    22021 taaaacttca ttagtttact tcttcaactg ttactaagtg agatactgct gtaatcatac
    22081 cacggatagc agcgttatct tctttaataa cagagctgtt caatttgcca agtccaagtg
    22141 ctacaacagt tttacgttgt gatggaatgc gtccgattgg agacttagtc aaagtaattt
    22201 taatttgagc cattttatcc cctttcttat gccaaatcag aaactgaaat accacgaagg
    22261 gcagcaattt cttcagcgcg tttcaattgt ttcaaacctt caacagttgc acgaacaatg
    22321 ttgattggag tgttagaacc aagtgattta gatgtaatat ctgccacacc tgccaattcc
    22381 acaacggcac gaactgcacc accagcggca actccagaac cttctacagc aggtttcaac
    22441 aatactttag ctccaccgaa ttctgaaaga acttcgtgtg ggattgttgt tccaaccata
    22501 ggaacttcga tcaagttttt cttagcatca tctactgctt tacggattgc ttctggaact
    22561 tcttgagctt taccagtacc aaatcctacg cgaccattgt ggtcaccaac aacaacaaga
    22621 gctgcgaaac gaagacgacg tccaccttta acaacttttg taacacggtt gacagcaact
    22681 acgcgttctt ctaattcaac tgcattgtct ttaaatgcca ttttctagtg tcctcctatt
    22741 agaatttcaa tccgttttca cgagctgcat cagccaaagc tttcacacgt ccgtgatata
    22801 gatatccacc gcggtcgaac accacttctg aaataccttt agcgtttgca cgttctgcaa
    22861 cgagtttacc gacagcaacg gcttgttcag ttttagttcc ttttgaaact tctttatcaa
    22921 gagttgaagc acttgcgagc gttacacccg ctacgtcatc aatcacttga gcgtagatgc
    22981 ctgtattaga acggaatacg ttcaaacgtg ggcgatcagc agttccagag agttttccgc
    23041 gaacgcgacg gtggcgtttt tggcggagtt tgtttttatc tggttttgaa atcacagttt
    23101 tcacctcttt agttttaaat cgtgtgctat gcacaaagtt ggaaaatagg ttggtggttg
    23161 atgatcaacc actcaacatt atttacctgt tttaccttct ttacggcgaa cgaattcacc
    23221 aacgtaacgg atacctttac ctttatatgg ttctggtgaa cgaaggctac gtacgtaagc
    23281 agctgtttga ccaactactt cttttgaaat tccgctaaca acgattgttg ttgggtttgg
    23341 aagttcaaaa gtaattcctt ctggagcttc aacttcgtct ggatgagatt taccaacagc
    23401 caaaacaagt ttagatcctt gaagctgtgc acggtaacca accccacgca tttcaagttc
    23461 tttcttgaat ccttctgata caccaacaac catgttgttc aaaagggcac gagtagttcc
    23521 gtggatagtt ttcatttctt ttgaatcgtt tggacggtga agagttattt cagtaccttc
    23581 cacacggatt tcaatatctt ttgagaactc acgagtaagt tctcctttag gtccttttac
    23641 agttacaacg ttgtcattgt tagcgagttc aacaccagca ggcaacacga taactttatt
    23701 accaatacgt gacatgttta ttttctcctg ttaaattgtc aggccagaac ggccagtttt
    23761 cacggggttc agatacttat ttagttcaag agctgaactg aacacgctct aagaactgtg
    23821 caaaatagat aagttggctt gtttgtaaac aaacttctcc aacttcctaa ttttgctttg
    23881 ttctttacga gctttgtatc ttgattttac caaacgtaag cgataacctc accaccaaca
    23941 ttcttttggc gtgcttcttt atcagtaagc aaaccttcag aagttgaaag gatggcaatt
    24001 ccaagtccgt taagaacttt tggaaggtct tcacgttttt tgtagacacg aagtcctggt
    24061 ttagaaacac gtttcaagtt agtgataact ttctcaccat ttggtccgta tttaagaaat
    24121 acacggatga cgccttgttt gtcatcttca atgatttcaa cgttttttac aaaaccttcg
    24181 cgtttaagga tttcagcaat cccttttttg atgtttgatg caggtacttc aagtacttcg
    24241 tgtttagctt ggttagcatt acgaatacga gttaggaagt ctgcgattgg gtcagtcata
    24301 accattttgt ttttctcctc ttactagtag tttgcaagtt gcacttgcta gttaatacat
    24361 gatacaaaga gcgtaacagc acgagcaaaa atagacaatt taatgcagaa gcaatgctcc
    24421 aaagcaaatt agtctttttt gccaaagctg tagctcgtgt tcaaattggc aagcccaatt
    24481 gaacccgggc taaactctgt gtgaaaaaga taaactttcc tagaaacttt agtttcttcg
    24541 tcaagtttcc tatttttact tggagttttg acgctcttga tatcttaaat taccaagatg
    24601 cttttgttac accaggaatt tgacctttat gcgcaagttc gcgaaaagcg atacgactca
    24661 gaccaaattt gcggtaaact gaatgtgggc gccccgtaac cctacaacga ttatgtaaac
    24721 gagtcggtga ggcgttgcga ggtaatttag ataaaccttc gtagtcccct gccgccttta
    24781 atgcagcacg tttttcagca taacggtcaa caattttttg gcgtttagcc tctctagcta
    24841 ccattgattt tttagccatt agatttacct cctatattat tttgcaaaag gcattccaag
    24901 gcctgtaagc aatgcacgtg actcttcgtc agtgttagca gttgttacga taacgatgtc
    24961 aagaccacga gttttgtcaa cgtcatcgaa gttgatttct gggaagatta attgttcttt
    25021 cacaccaagt gtgtagttcc cgcgtccatc aaatgatttt gttgggacac cgtggaagtc
    25081 acgtacacgt ggaagtgaaa ctgataccaa tttatccaag aattcgtaca tacgttcacc
    25141 acgaagggta acttttgcac cgatcgcaac accttcacga agacggaagc cggcgattga
    25201 ttttttagct ttagtgataa gtggtttttg acctgagata agtgccaatt cttcagcagc
    25261 tttttcaagg cttttagcgt ttgatacagc ttcaccaaca cccatgttca aaacaatctt
    25321 atctacttta ggcacagcca tcactgatga gtagttgaat tgttctgtca aagcaggaac
    25381 tacttcatta agatattttt cttttaaacg atttgccatt atacttctcc tttccttcgt
    25441 gattaatcaa gcacttcgcc tgattttttg ttgtagcgaa cttttttacc gtctacaaat
    25501 ttgtaaccaa cacgaccagc tacaccattt ttgtccaaaa cttgaacatt tgatacgtgg
    25561 atagctgctt ctttctcgat gataccacct tgaggaagct cgttagttgg acgttggtgt
    25621 ttcttaacaa tgttaacacc ttcaacgata actttgttta cttttggaag ggcagtaagg
    25681 acaacagctt ctgttccctt atctttacca gcgattacgc gaactttgtc gccttttttt
    25741 acaaacatta ggtttctcct tgatttttct tacgcccata agggcaccct agcttgaagc
    25801 taggggacta gtttgttcct aaaaattaaa gtacttctgg agcaagtgac acgatcttca
    25861 tgaaaccacc ttcacgcaat tcacgtgcaa ctgggccaaa gatacgtgtt ccgcgaggag
    25921 ttttgtcttc acggatgata actgctgcgt tttcgtcaaa tttgatgtat gaaccatcag
    25981 cacgacgagc acctgattta gtacgaacga taactgcttt aacaacgtca ccttttttaa
    26041 ccgcaccacc aggagtagct tgttttacag atgccacgat aacatcaccg atgtttgcaa
    26101 atttacgtcc tgaaccacca agaactttga tagtcaagat ttcgcgagca ccgctgttgt
    26161 ctgcgacttt caaacgagtt tctgtttgaa tcatttcagt tttctccttt caggtttgat
    26221 tagatgatga ccgcttcttc aacaacttct acaagacgga aacgttttgt agctgaaagc
    26281 gggcgagttt ccatgatacg tacgatatcg ccttctttgg caacattgtt ttcatcatga
    26341 gctttgtatt ttttagagta gttaatacgt ttaccataga ctgggtggtt acgttttgtt
    26401 tcaactacaa ctgtgattgt cttgtccatt ttgtcagata caacacgtcc aacaagaact
    26461 ttacgattat tgcgttccat tgaaatttct ccttccctag tctattattt cgcttcagat
    26521 tgaactgttt tgatacgagc gatttgtttt ttaacttctt tcaagcgagc tgtttgttcc
    26581 aattgaccag tagcagcttg gaaacgaagt tcaaacaatt cttttttcaa ttcgttttcg
    26641 cgcttcgcga gttcttcttg agaaagacca cgaagttctt taacaaattc ttttacttca
    26701 ttaagtttca tgccttctcc ttattctgct tcacgtttta cgaatttaca tttaactggc
    26761 aatttgtggc tagcaagtcg aagcgcttca cgtgcaatct cttcagatac accagcgatt
    26821 tcgaacatca ctttaccacg tttaactggt gctacccaac cttcaggtgc ccctttacca
    26881 gatcccatac gcacaccgat agctttagca gtgtatgatt tgtgtgggaa gattttaatc
    26941 caaactttac caccacgttt catgtaacga gtcatggcga tacgagcagc ttcgatttgg
    27001 cggttagtga tccagtggct agttgtagct tgaagaccgt attcaccgaa tgctacttct
    27061 tttccacctt ttgcttcacc gcgcattttt ccacggaact cacgacggtg tttaacacgt
    27121 ttaggtacta acattggtta tttacctcct ttagtgtttt tacgagctgg aagaacttca
    27181 ccacggtaga tccatacttt aacaccaagt ttaccgtatg tagtatctgc ttcttcccaa
    27241 gcgtaatcga tatctgcacg aagtgtgtga agcggaacag ttccttcaga gtatccttca
    27301 gcacgggcga tatctgcacc gttcaaacga cctgatactt gagttttgat tcctttagct
    27361 ccagcacgca ttgcacgttg gattgcttgt ttttgtgcac gacggaaagc aacacgttgc
    27421 tccaattgac gagcaattcc ttcacctaca aggtgagcat ccaaatcagg ttgtttgatt
    27481 tcgatgatgt tgatgtgtac ttgttttcca gtcaatttgt taagttttgc acggagtgca
    27541 tcaacgttag caccaccttt accgataacc atacctggtt tagcagtgtg aagtgaaacg
    27601 ttaactttgt ttactgcgcg ttcgatttca atagttgaaa ctgctgcgtc agcaagttct
    27661 ttttgaacga atttacggat tgcaagatct tcatgaaggt aatccgcgta ttctttttca
    27721 gcataccatt tggcatccca atcacggatg atgccgacac gcataccaat tggatgtact
    27781 ttttgaccca cgattttacc tccttatttt tctgcaacag ctacagtgat gtgagctgta
    27841 cgtttgttga ttggtgaagc tgaacctttc gcacgtggac ggaaacgttt catagttggt
    27901 ccttcgtttg cgaatgcttc agatactacc aagttagctt tatccaaacc aaagttgttt
    27961 tcagcgttag ctacagctga gttcaaaact ttcaagatga tttcagcagc tttgtttgga
    28021 gtgaatgtca agattgcgat tgcatcggct acgcttttac cacggatgtt atcaagaaca
    28081 agacgtgatt tacgaggtga aacacgtact gtacgagcca ttgctttagc tgaagtaatt
    28141 tctgccattt atgttctcct tattttctac gtgttttctt gtcgtctgca gcgtgacctt
    28201 tgtaagtacg agttggtgca aattcaccaa gtttgtggcc taccatgtct tcttggatgt
    28261 aaacaggtac gtgtttacgt ccgtcataaa ctgcaatagt gtaaccaatg aaacttggga
    28321 agatcgttga acgacgtgac caagttttaa taactttttt cttttcgtcg ttagcttgag
    28381 cttcaacttt tttcatcaaa tgctcatcga cgaaaggtcc ttttttaaga ctgcgtccca
    28441 tttttatatt ttctccttta aatgttgtac cacagcggct tgcactccta tggagcgcta
    28501 ccgagctggc ggatttacta gttgcttaag cgactagttt aatattattt ctcgttgcga
    28561 cgacgaacga taagtttgtc agatttcgct ttcttgttac gagttttaag accaagagca
    28621 ggtttgcccc atggagtaga tggtgcttta cgaccaactg gtgctttacc ttcaccacca
    28681 ccgtgtgggt gatcgttagg gttcattaca gaaccacgaa ctgttgggcg gatacctttc
    28741 caacggctac gtcctgcttt accaaggttt acaagtccat gttgttcgtt tccgacaaca
    28801 ccaactgtag cacggcaagt tccaagaatc atacgaactt cacctgattg aagacgaaca
    28861 agaacatatt taccttcaga acccaatact tgagcagatg caccagcagc acgtaccaat
    28921 tcaccaccac gacctggttt caactcgatg ttgtgaatca aagtaccaac tgggatgtta
    28981 gcaagtggaa gagcgtttcc gactttgata tctgcttctg gacctgaaac gatacgttga
    29041 cctacttcaa gaccttttgg agcgatgatg tatgctttca caccgtcagt gtagtgtaca
    29101 agagcgatgt ttgcagaacg gtttggatcg tactcgattg ttttaacaac tgcttcaacg
    29161 ttgtctttat tacgtttgaa gtcaaccaaa cggtagaaac gtttgtgtcc accaccttgg
    29221 tgacgaactg tgatacgacc gttgttgtta cgaccagcct tgctcttcaa tgcaacaagc
    29281 aatgattttt caggagtgct tgttgtgatt tcagcgaaat ccaaagaagt catattacgg
    29341 cgaccgtttg ttgttggttt ataaacacga attcccacga tatttcctcc ttagattatt
    29401 cagcttcagc agcaaacaac tcgattgctt tagaatcagc tgtaagtgtg atgatagctt
    29461 ttttagtttt gttagtaaaa ccagtgtaac gtccaacacg tttagctttt ggttttacgt
    29521 tgattgtgtt aacattggca actttaacac cttcgaaagc agcttcaaca gcttgcttga
    29581 tcaaaagttt gtgtgcacga gtgtcaactt caaatacata tttccctgct tcaagttgag
    29641 ccattgagct ttcagtgatg acaggttttt tgataacatc atacaaattc attatgcaag
    29701 aacctcctcg attttagaga tagctgcttg tgtgacaaga agtttgtcgc tatttgcgat
    29761 gtcaagaaca cttgcagttg tagcagttgc aactttcacg tttggaaggt tacgagctga
    29821 aagagctgcg aattcatttc cttcttcaag gataacaaga actttagaat cgatgctcaa
    29881 tgctgcaaga acttttgcaa attcagcagt ttttggagct gtaaatgaaa gagcgtctac
    29941 agctacgaat ttgttttcag caactttttc agagtaaact aatttaagag ctaggcgacg
    30001 aactttttgt ggaagtttgt agccgtatga acgtggagtt ggtccgaaga caacaccacc
    30061 accacgccat tgtggtgagc ggatagaacc ttgacgagca cgtccagttc ctttttgacg
    30121 ccatggtttg cgtccaccac ctgatactgc agagcggttt ttaacagcgt gtgttccttg
    30181 acgaaggctt gcgcgttggc tgatgattac atcaaacaca actgattcat ttggttcgat
    30241 accaaatact gcatcgttaa gaacaacttg gccagcttct ttaccagttt ggtcaaataa
    30301 tgttacgttt gccattgtga ctgatttccc ctttctttat tatttaccag ctttaactgc
    30361 tgatttgata gtgataagag atttcttagc acctggtacg ttacctttga taaggataac
    30421 gttcttttct ggaacaactt gtacaacttc aaggttttga attgttacgc ggtcgccacc
    30481 catacgtcct gcaaggtttt tacctttgaa tacgcggtta ggtgcaacag gccccataga
    30541 acctggacga cggtggtaac gagaaccgtg agccattggt ccacgtgatt gtccgtggcg
    30601 tttgataaca ccttggaaac ctttaccttt agaagtacca gttacatcaa caacatctcc
    30661 agctgcgaat gtttcaactg tgatttcagc gccaacttcc aagccttcaa cgtttttgaa
    30721 ttcacgaatg aagcgcttag gagccgtgtt agctttcgct acatgtcctt tagcaggttt
    30781 gttgctcaat acttcgcgtt tgtcatcgaa accaacttgg atagcgttgt atccgtctgt
    30841 ttcaacagtt ttaacttgaa gaacaacgtt tggagttgct tcaataactg ttacagggat
    30901 caattcgcca gcttcagtga agatttgagt cattcccact tttttcccta agattccttt
    30961 tgtcatgaga aaatagttcc ttttctatat tttttattca aaaagttttt aacgagcgtt
    31021 ttttatgctc aagtctaaga tacaaagggc gtcaaactca aagtgaaaat aggaaactaa
    31081 cgcagtgtct agcggacaat aggaagttta tctttttcac accgagttta gcccgtgttc
    31141 aattagattg aaacaccagc ctctgctctt ttatatttta gattaaagtt tgatttctac
    31201 gtttacacca cttggaagat ccaatttcat caaggcatca actgtttttt gagttgggtt
    31261 aacgatatcg atcaaacgtt tgtgtgtacg catttcaaat tgttcgcgag agtctttgta
    31321 tttgtgagtc gcacgaatga ttgtgtagag gctacgttca gttggaagtg ggattggacc
    31381 cgcaacttgt gcacctgtac gagtagctga ttctacgatt tttgcagccg ctgtgtcaag
    31441 cgtacggtgt tcgtaagctt tcaaacggat acggattttt ttgtttgcca tctttttctc
    31501 cttttcgtct atttaagata ataggctagc tccacaagaa aaccgacgcg gtgttgcgtg
    31561 gcaatgcaac cgagcgtgtc gcaacctctt gcatcaaaac taaggctgta atttacagca
    31621 ccataataga ataacacaaa tcccctgcga ttgcaaggga tttgttaggt tttttcgttt
    31681 ttttgggatg aaactgtttt cctacttttt ctttctaaaa ttagggattt tcttctatat
    31741 ttcttctata cataagttaa gtcctcttga catcaaattt atcttctgat tggtccacta
    31801 agatatccgc cttagactca gtttctttat agtatcgcag atactgctcc cgtctcatct
    31861 gatggctagc caatataaag gatgcatagc gatttctcac agtcgtatct ctagcaaggc
    31921 gtcgctttaa ttcggtctcc tcatccgtgt agaaacagat ggttttttca aagagttcct
    31981 tgggtagaaa accaacagac atcccttcga caatcaaaat tggtttggct ccagacaaga
    32041 cctcactagc cttccaaggt tcttcaattg tcaagacatc catacccgcc tgcaaggcaa
    32101 ggatatctct ctgcaaactc tccagttcat gcgccactgg cagactggct gtcacctttt
    32161 gattcggcgc gtccttgggt actaccaaat agcgtccgga ggtgatatag ggatctgttt
    32221 ctagcaaatt ta
//
LOCUS       DBEJKC010000023        32064 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.023, whole genome shotgun sequence.
ACCESSION   DBEJKC010000023 DBEJKC010000000
VERSION     DBEJKC010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32064
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.023"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(10..732)
                     /locus_tag="ACL3G6_001065"
     CDS             complement(10..732)
                     /locus_tag="ACL3G6_001065"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGR0545613.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DINTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     KPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            complement(1045..1275)
                     /locus_tag="ACL3G6_001066"
     CDS             complement(1045..1275)
                     /locus_tag="ACL3G6_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGR0545614.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            complement(1285..2526)
                     /locus_tag="ACL3G6_001067"
     CDS             complement(1285..2526)
                     /locus_tag="ACL3G6_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HGR0545615.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDLLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVIFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSLVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(2548..2700)
                     /locus_tag="ACL3G6_001068"
     CDS             complement(2548..2700)
                     /locus_tag="ACL3G6_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545616.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            complement(2721..2999)
                     /locus_tag="ACL3G6_001069"
     CDS             complement(2721..2999)
                     /locus_tag="ACL3G6_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HGR0545617.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(2992..3255)
                     /locus_tag="ACL3G6_001070"
     CDS             complement(2992..3255)
                     /locus_tag="ACL3G6_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HGR0545618.1"
                     /translation="MSKMSMSIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQVLTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            complement(3357..7748)
                     /locus_tag="ACL3G6_001071"
     CDS             complement(3357..7748)
                     /locus_tag="ACL3G6_001071"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HGR0545619.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VDKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     GAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            complement(7852..9933)
                     /gene="fusA"
                     /locus_tag="ACL3G6_001072"
     CDS             complement(7852..9933)
                     /gene="fusA"
                     /locus_tag="ACL3G6_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HGR0545620.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            complement(10358..10828)
                     /gene="rpsG"
                     /locus_tag="ACL3G6_001073"
     CDS             complement(10358..10828)
                     /gene="rpsG"
                     /locus_tag="ACL3G6_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HGR0545621.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            complement(10848..11261)
                     /gene="rpsL"
                     /locus_tag="ACL3G6_001074"
     CDS             complement(10848..11261)
                     /gene="rpsL"
                     /locus_tag="ACL3G6_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HGR0545622.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            11678..15475
                     /gene="spuA"
                     /locus_tag="ACL3G6_001075"
     CDS             11678..15475
                     /gene="spuA"
                     /locus_tag="ACL3G6_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HGR0545623.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWHLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDLAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVRNESVENSSKENIPATPDRQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            complement(15575..16624)
                     /locus_tag="ACL3G6_001076"
     CDS             complement(15575..16624)
                     /locus_tag="ACL3G6_001076"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HGR0545624.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SDGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHIPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            16681..16818
                     /locus_tag="ACL3G6_001077"
     CDS             16681..16818
                     /locus_tag="ACL3G6_001077"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545625.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDRTNEVSNHTYGKATLTWFEEI
                     F"
     gene            complement(16895..18703)
                     /gene="glmS"
                     /locus_tag="ACL3G6_001078"
     CDS             complement(16895..18703)
                     /gene="glmS"
                     /locus_tag="ACL3G6_001078"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HGR0545626.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYFEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(18896..20275)
                     /gene="bglA"
                     /locus_tag="ACL3G6_001079"
     CDS             complement(18896..20275)
                     /gene="bglA"
                     /locus_tag="ACL3G6_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGR0545627.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            complement(20375..22228)
                     /locus_tag="ACL3G6_001080"
     CDS             complement(20375..22228)
                     /locus_tag="ACL3G6_001080"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HGR0545628.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            complement(22241..23500)
                     /gene="rseP"
                     /locus_tag="ACL3G6_001081"
     CDS             complement(22241..23500)
                     /gene="rseP"
                     /locus_tag="ACL3G6_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HGR0545629.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTVLPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPKDSQG
                     RYLLGVQPGGKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            complement(23522..24325)
                     /locus_tag="ACL3G6_001082"
     CDS             complement(23522..24325)
                     /locus_tag="ACL3G6_001082"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HGR0545630.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            complement(24334..25092)
                     /locus_tag="ACL3G6_001083"
     CDS             complement(24334..25092)
                     /locus_tag="ACL3G6_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HGR0545631.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            complement(25323..25895)
                     /locus_tag="ACL3G6_001084"
                     /pseudo
     CDS             complement(25323..25895)
                     /locus_tag="ACL3G6_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
     gene            complement(25876..26874)
                     /gene="ruvB"
                     /locus_tag="ACL3G6_001085"
     CDS             complement(25876..26874)
                     /gene="ruvB"
                     /locus_tag="ACL3G6_001085"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HGR0545632.1"
                     /translation="MSRILDNEMMGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEA
                     AKMRDEALDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELE
                     PGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPR
                     IANRLLKRVRDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGG
                     PVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            27008..27100
                     /locus_tag="ACL3G6_001086"
     CDS             27008..27100
                     /locus_tag="ACL3G6_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGR0545633.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            complement(27915..28331)
                     /locus_tag="ACL3G6_001087"
                     /pseudo
     CDS             complement(27915..28331)
                     /locus_tag="ACL3G6_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(28343..29035)
                     /locus_tag="ACL3G6_001088"
                     /pseudo
     CDS             complement(28343..29035)
                     /locus_tag="ACL3G6_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144882.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(29335..31836)
                     /gene="leuS"
                     /locus_tag="ACL3G6_001089"
     CDS             complement(29335..31836)
                     /gene="leuS"
                     /locus_tag="ACL3G6_001089"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HGR0545634.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDTSKPKFYALDMFPYPS
                     GVGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDISREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
BASE COUNT         9314 a         7536 c         6104 g         9110 t
ORIGIN      
        1 taaactaaat taaataatat tagcgcggag aatttctaat tcttccttgg tcaagcgacg
       61 ccattcccct cgttccaggt tctcatctaa tactaaagtt cccatagtca atcgttgcaa
      121 gtccaccact tccttgccac agtagcccac catacgcttg atctgatgaa acttcccttc
      181 tgcaatggtc acacggattt ggctttgatt cttttctgta tctatggata caagctccag
      241 tatagcgggt ttacaggtaa agtctttgag aggaataccc tcagcaaatg tctccacatc
      301 ttcttgggtc atgattccct tgacttgtgc cagataagtc ttgtccacat gacgcttggg
      361 cgaaagaaga acatgagcca gctgaccatc attggtcaag agcaaaagac catgcgtgtt
      421 aatatccaag cgtcctactg ggaaaacttc cttactccgc gccaagtcat ccaacaagtc
      481 cagaacggtt ctgtgcttgg gatcctcagt cgctgagata actcctttgg gcttgttcat
      541 catgtagtag acaaactctt catactccaa cacttgccca tcaaagcgaa tctcatctat
      601 tttttcatca atctgcaatt tagctgattt ttctttttta ccatttacag tcacgcgccc
      661 agccttgagc aagtttttga cctcagtccg acttcccacc gcacaggcaa ctaaaaattt
      721 atctaatctc atagaactat tatatcatat caaaaggagg ctggtacaat gaccaacctc
      781 cttttcgttt catactcttc aaaaatctct tcaaaccgcg tcaacgtcgc cttgccgtat
      841 atatgttact gacttcgtca gttctatctg caacctcaaa acagtgtttt tagctgactt
      901 cgtcagttct atctgcaacc tcaaaacagt gtttttagct gacttcgtca gttctatctg
      961 caacctcaaa gcagtgcttt gagcaacctg cggctagttt cctagtttgc tctttgattt
     1021 tcattgagta tcagatttag gaaattaact tcctcgtctc caaaaaatag ctaagacaat
     1081 catggcacct aaaacagctg ggataatagc tgttcctgat aaaactggcc cccaagttcc
     1141 aaagagcaag tgacctagaa aggctccgat ccaaccgaga aacatttttc caaaacatcc
     1201 cattcgctct ccacgattgg tcatagcacc tgctaaaaat cccactagga gaccaacgaa
     1261 catacttcct aacatattat ctccttaatt tgcccaattc ccattacgga aaagaggtac
     1321 ccgcgttcca tcctcacgaa taccatcgat atccatttgg ttagaaccaa tcataaagtc
     1381 tacgtgaaca tctgaacggt taagccctgc agcttcaagc tcctcttcgc tcatctccgc
     1441 tccatcaaca aggctagtcg cataggctgc accgatagcc aagtggtttg acgcattttc
     1501 atcgaaaagg gtgttaaaga aggtaatgcc tgactgagaa attggacttg gatctggtac
     1561 caaggcacat tcacccaagg cacgcgcacc cgcattttca aagacaaggt ctttcataac
     1621 ctgatcaccc ttctcagcag tgatatctac gatttgtcca tccttaaaga tcaccttaat
     1681 gccttcaatg atatttccgt tgtagctaag cggttttgta gaagtgacat aaccatctgc
     1741 acgacggaag tcaggcgctg tgaagacctc ttctgtcggc atatttggca agaatccttc
     1801 gccctgtgca ttgacagcac cagctgattc ccaaacgtgg ttctttggca aaccaagtgt
     1861 taaatctgtt cctggcgctg tgtagtgaag ggctgaaaat tgctccttat taagcatatc
     1921 ggccttgctc ttgagaatgg ctgcatgctc ttcccaggcc ttaacaggat ctgcttcgta
     1981 gacacggcaa gttttgaaga tttggtccca aaggagatcg actgcttctt cgtcgctcgc
     2041 agcatttggg aagactttct tagcccactc aagtccagca gcggctgcta cagtccagct
     2101 aaccttgtta gattgagttg cgattcgcat tggcttcatg gcaagtccca tagctttagc
     2161 agaagctgaa agcttgtcag cgtccactcc gttcaaggca cctggatcag atgaacgaac
     2221 tccaagacgg ctagccttgt tctccaagag atagttcatc tcagcaatct tgtattctgg
     2281 cacattgtcc aaacgctcca tcggggcatg gaggaatttc tcacggttaa tcacatcatc
     2341 tgtccactga acgatgacct catgcgcacc caaggcataa gcttctttca cgattagatg
     2401 tgccaattca cgttgctcca catcaataga gagagccaaa gtgtgaccag gttgcacgtt
     2461 aattccgttc gcaaccaaca atttcgcata tttttctaga ttttctttaa aatttggtaa
     2521 aaccatcctg ttttctcttt tctattttta tttttctttc aaagcagaaa agattcctgc
     2581 taaagcaata gcacctgaca agagtgctgt cgataaaaga attgtacgat cagcaagttc
     2641 taattgatat tcaaatacct tcttagccgg cttatcttcc gcaaatattc ttagtttcat
     2701 gagaaccccc ttaaaataga ttaaaataaa tcactgtgac tgcctgtcct cagcaaattt
     2761 aaaatcaatt ccgacttatc tactttataa accaaaagcc aatctggctg ggtatggcat
     2821 tcacgaactc cttgaaaatg cttggatgcc gtcaatgaat gatcacgata tctggcagga
     2881 tgttcttttt cttgaaccag aaaattcaaa acttcttcta ataattctgc cttcaaacca
     2941 cgcttcatag ccaacttaaa atctttttta aactgtttat gataacgaat cttaagcacg
     3001 taagtcctcc atcaaatctg agactgattc aaaagactgg ctcatattac gattttggtc
     3061 taaatccgtt aacacttgga gcaacttccg attttcgtct agtctaacat caaaaggtaa
     3121 tccctgatat tgaattgcct gacgaaggaa aatattaata gctgttgtca tatccattcc
     3181 cagattacta aacacctgtt gggcctgctc cttaacctca ctatccagac ggatgctcat
     3241 actcatcttt gacatactct caccctcttt ccatagacta ttttaacaaa aaagaaagct
     3301 aatgtaaatc tattggatat acgttagcct cttctaatag attattaagc aattttttaa
     3361 aacaactcat caaacaaact caactggtta tcctctggca tatttccaag aatacccatc
     3421 tcatccatct tttcaaccaa ggttgatgag agtccaccac gcttgcgtag ttctgtttta
     3481 gagaggaatt ctccctcttc acgcgcccgc accagttgct tggcaacgtt ctctcccaga
     3541 ccatccattg ctacaaatgg tgggataagg gtatccccgt cgatgaggaa ctctgtcgcc
     3601 tgactacggt agagatctaa tttgccaaac ttgaaacctc gttcccacat ctcattgaca
     3661 atctcaagag ttgtatagag atcgatttcc acattagagg cttcattgtt cttccgtttt
     3721 tcagagattt cttccattct gcgcttgatg gcctccaagc ccgcacccat ggtcttgata
     3781 tcaaaagcct tagcacgaat ggagaagtaa gcacagtagt aataaatagg atggtgaacc
     3841 ttgaagtaag ctacacgcaa ggccatcata acgtaggctg ccgcatgggc cttagggaac
     3901 atgtacttaa ttttcccaca ggattcgata taccactctg gcaccttatt agccttcatg
     3961 gcttcgatat agccatttct ctcctcttct gaaatcttta gccacaaacc cttacgtacc
     4021 cgttccataa tggtaaaggc catcttaggt tccagacccg catgcatgag gtaaaccatg
     4081 atgtcgtccc gacaaccgat aacagtcgat aggtccgcta ttccttgctt aatcagatcc
     4141 tgagcattcc ccaaccaaac gtcagtaccg tgggacagac cagacagctg aagcaattcc
     4201 gcaaaggttg tcggatgggt ttcgtctacc attccacgta cgaaatttgt tccaaactct
     4261 ggaatcccca acatacccgt aggcgttcca atttgttcag gtgttacccc tagcacatca
     4321 gtcccagaaa agagtgccat cacgccttcg tcatccatag gaatttcatt agggtcaata
     4381 ccagacaaat cctgaagttt tcgaatcatg gtcggatcat catgtcccag tacatcgagt
     4441 ttgaggacgt tctcatcgat atcgtggaag ttaaagtgag tggtctgcca ttcagccgtg
     4501 acatcatctg ctggatactg gacaggcgta aaatcgtaga catccatgta gttcggaata
     4561 acaacgattc cccccgggtg ttggcctgtt gtccgcttga cacccgccgc tccttgagcg
     4621 aggcgttcta cttctgcatc acgataaaac ttgccataat ctcgctcgta acccttgaca
     4681 aatccatagg cagtcttggc agctaccgta ccaaccgttc ccgcacggaa ggcatattct
     4741 tcaccaaaga tatcacgcac atccaagtgg gcgctaggct gatcttctcc cgagaagttc
     4801 aagtcaatat caggaacctt atccccatca aagccaagga aggtctcaaa cggaatatcc
     4861 tgtccgtttt tactgagttt gtgaccacag tttggacagt ccttatgggg catatcaaat
     4921 cctgaaccgt acgaaccatc tgtgataaac tcactgtact gacactgacc acagacatag
     4981 tgaggagaga gaggattgac ctccgtaatc ccaatcatgg tcgcaacgaa actagatccg
     5041 acagacccac gagaaccaac caaataaccc cgttcattag aacgttgcac cagcatctgc
     5101 gatgccagat aaatcacagc aaatccattc cccagtatgg atgttaattc tttttcaatc
     5161 cgcaaatcaa caatatctgg cagcggattt ccataaatct caaaagcttt cttataggtc
     5221 aactcagcaa ctgtttcttc agccttgtcg atgaaaggcg tatacaagtc acccttaacg
     5281 acttcaacgg gttcaaatat ttctgccaag gcattagtgt tttcaataac cagtttacga
     5341 gccagttcct ctcccaaaaa ggcaaattca tccaacatct cattagtcgt tcgaaaatga
     5401 gcctttggaa gtggtgctgg ttgggcatgt tcaccatgac cgatagttcg attaatcatc
     5461 gcaccctgtc ccaaactacg gacaataatt tcacgataaa tctcttcttc cggttcgata
     5521 tagtgaacat ttcccgtagc cagaacaggc ttgccaaggc gatctccaac ctctatcaaa
     5581 ctcttgataa tggtctggag ttcctccata tccttgacct gctctttggc aatcaagggc
     5641 gcatagatag ccggtggcat gacctcgata aagtcataat acttggccac ctcaaccgcc
     5701 ccatccacac cttgagaaac gaccacgtca aaaacttcac cctctgaaca ggctgaacct
     5761 aaaatcaagc cctctcgatg ggcatctaga accgttctcg gaatccgtgg cactccttca
     5821 aaatacttgg tattagacaa ggaaaccagc ttaaagatat tttttagacc tacctgattc
     5881 ttgacataga tggtcgcatg cttgatccga gcttttttgt aagaatctgg actgattaga
     5941 tcaatgttga gtctagctaa atcggtcaca ccatgttttt ctgctacctc tttgataaag
     6001 atgaaaagca gacgaccagt cgcttccgca tcgtaattgg ccatgtggtg atgttccaag
     6061 gccacaccaa aacgcttggt caaaggcccc aaaccatggc gtttatactc aggatagagg
     6121 tttctagcaa actccagcgt atcaataact ggctgactaa tctttggaag accatgacgc
     6181 tcataattag cattcataaa gccaacgtca aaggtagcat tgtgggcaac taggaccgta
     6241 tccttgcaaa attcttggaa ttcttgcaaa acttgttcta gtggtttggc atttttgaca
     6301 tgatcatctg taattccagt taactctgta gtaaaggctg acaagggatg cccaggattg
     6361 ataaattcat caaattcagc aataacattc cccttgtaca tcttagaggc cgcaacctga
     6421 atcaagtcat tatagatagc tgaaagtccc gtcgtttcca cgtcaaagac cacgtaggtt
     6481 gcttctgaca agtccatctc cacttcgtta tagacgatag ggacacggtc ctccacgata
     6541 ttggcttcca tcccatagat cagctggatt cccgctttct tagccgcctt atagccatgt
     6601 ggaaaggact ggacattccc atggtccgtg atagcaaccg ccttgtgtcc ccacttagca
     6661 gctgttgcaa caatctcttc gacctctggc aaagcatcca tagtcgacat gttagtatga
     6721 gcatgaaact caacccgacg ctcaccttct ggcatcaaat ccttccgctc atagtgaaca
     6781 acttcctgca gatcctgtac gttcatagtc aaatcgcgtg tgaagttatt catctccaca
     6841 ttccctcgaa ctcggagcca agaattcttc ttgatgagat caaacttctg ggcctcttcc
     6901 tcgtttttaa cccacttttg catagaaaaa cttgaagtgt agtccgtcat tttaaagttg
     6961 attaaaacac gacctgttct agtcactttt tgctccacat caaaaacaac cccttcaaat
     7021 accagacgat tttcctctgt cgtcacttcg atcataggag taatctccgc cttatccagc
     7081 ttgggtttag ctgcagcttt tttcgcttga aaatcaaaga ctggtttctc ttccgctgga
     7141 ggaggtgcca tctgctccag ttgttccata gcacggagcg cttcctcatt ggcagcttga
     7201 acaatctgct cattttcagc atgaaaggcc tcttcctgct cttgggtcag gacatcattc
     7261 ttatcgactt gacagttaaa agttggaaaa ccaaactttt caagttgttt ggctaaatta
     7321 ggaagatgat tcttcttaaa atgttcctta tcaatcgcct cagatccttc aataaatagc
     7381 tgattaccct cagcacgaac ttgcaaattt tgataaaggg acttaaaacc ttgactagca
     7441 catggacctt cagagaaagc ctccctatag taggactgca agagctgatt tgaaaattct
     7501 tgagaccgag ccttaatttc aaaaacagct ttattgcctg tcttagaaaa ttcttcgctc
     7561 aaacctttct ttaattctaa aaagatttca atcggtaaaa tattagaaaa tacgaaatga
     7621 aactcccata ccttactaat tttatgaacc acaactcgct caatattggc ctgtgctaaa
     7681 gcaggagcct gtctcatttc agcaggcatc cccaattgat tcatcaaaat ttcaaaacta
     7741 tttgacattc attttcctca cattattctt ctactatttt accatattta gaggtatttt
     7801 ctaaagacaa aaggaagcca ctaagtgact tccttctaga gtgaggacgg attagtcttc
     7861 acctttattt ttcttaataa tttcttcttg tactgactta ggtacatctt cgtagtggtc
     7921 aaataccatc atgaatgtac cacgtccttg agatgcagaa cgaagaactg ttgcgtaacc
     7981 gaacatttca gcaagtggaa cgtaagcacg aacgatttgg ctgttaccgt gtgcttccat
     8041 accatctaca cgtccacgac gagcagttac gtgacccata acatcaccaa ggttttcttc
     8101 tggaacagtg attgttacaa gcatcattgg ttcaaggata gctggttgtg ctgatttagc
     8161 agcttcttta agggaaagtg aagccgcaat cttgaaggca gtttcagatg agtcgacatc
     8221 gtgatatgaa ccatcataaa gcttagcttt aacgtcaacc attgggtaac ctgcaagaac
     8281 accgttagcc atagattcta ccaaaccttt ttcaaccgct gggataaatt cacgaggaac
     8341 cacaccaccg acgattgcgt tttcgaattc gaatccttta ccttcttcgt ttggagtaaa
     8401 ttcaatccac acatcaccga attgaccttt accaccagac tgacgtttga agaatccacg
     8461 tgcttgagta gaagcgcgga atgtttcacg gtaagatact tgaggcgcac ctacgttcgc
     8521 ttcaactttg aactcacgac gcatacgatc aacaaggacg tcaaggtgaa gttcacccat
     8581 acctgagata actgtttcac cagtttcaac gtttgtttca acgcggaatg ttggatcttc
     8641 ttcagccaat ttttgaaggg cgatacccat cttgtcttgg tcagctttag attttggctc
     8701 aaccatcaat tggataactg gttctggaac gttgattgac tcaaggatga ttttagattt
     8761 ttcatctgtc aatgagtcac cagttgtagt atctttcaaa ccaacggcag cagcgatatc
     8821 acctgagtaa acagtgtcga tttcttgacg gctgttagcg tgcatttgaa ggatacgtcc
     8881 gatacgttca cgtttacctt tagaagtatt caatacgtat gaacctgatt gaagaacacc
     8941 tgagtaaaca cggaagaatg tcaaacgacc tacgaatggg tcagtcatga tcttgaaggc
     9001 aagagctgca aatggctctt cgtcagatgc tggacgagtt tcttcagcgt ctgtatctgg
     9061 gttaatacct ttgattgctg ggatgtcaag tggacttgga aggtagtcga taaccgcatc
     9121 aagcatcaat tgaacacctt tgtttttgaa ggctgaacca cacaatactg ggaagaattc
     9181 aacgttgata gtcgctttac ggataccagc tttcaattct tcgttagtga tttcttcacc
     9241 ttcgaggtat ttcatcatca attcttcgtc agtttcagca actgcttcaa tcaatttttc
     9301 acggtattct tgagcttggt caaggtattc agctgggatg tcttcttcaa ggatatccgt
     9361 accaaggtcg ttagtataga tttcagcttt catcttgatt aagtcaatga taccacggaa
     9421 gtcatcttca gaaccgattg gcaattggat tgggtgtgca tttgcttgaa ggcgatcgtg
     9481 aagtgtgctt acagagtaaa ggaagtcagc accgattttg tccattttgt tggcaaatac
     9541 gatacgtgga actccgtact cagttgcttg acgccaaact gtttcagttt gaggctcaac
     9601 acctgattgt gagtcaagaa cggtaaccgc accatccaat acacgaagag aacgttgtac
     9661 ttcgattgtg aagtccacgt gtcctggtgt gtcgatgatg tttacgcggt ggttgttcca
     9721 ttgagctgtt gtcgcagcag atgtgatcgt gataccacgt tcttgctctt gctccatcca
     9781 gtccatttgt gacgcacctt cgtgagtttc accgattttg tggattttac cagtgtagta
     9841 aagaatacgc tcagtagttg ttgttttacc ggcatcgacg tgagccatga taccgatatt
     9901 acgagttttt tcaagtgaaa attcgcgtgc catgaggttt gtttctccta tttatttttg
     9961 atttctattc tattataaca cgattttaat aaaaacggat aggcaggacc tacccgttct
    10021 caatgttttc atgctattgt tggtttcaac ttacgagatg gtaagctgag ttatagctaa
    10081 tactaatcga tttagctaat ttgaacccgg gctaaagtta gttagccgat gtgagctgga
    10141 acgggatgct gcgtgaaaaa gataaaactc cttgtattcg tcgaatactg cgtcagtttc
    10201 ctattttcac cttgcatcct taccgttcct agcatcatga tttagttgag ctcaagctaa
    10261 aagtctggag aaaaagatga atctcattgg ttgcaaccgc aacctgcttc gattccctat
    10321 tttctctggg actttcttaa cgctttcgca tcctatctta ccaacggaag tgtgcgaatg
    10381 cacggttagc ttcagccata cggtgagtat cttcacgttt cttaactgct gcaccagtgt
    10441 tgttagcagc atccaagatt tcttttgcaa gacggtcttg cattgtgtgt tcaccacgaa
    10501 gacgagcgat tgttaccaac caacgaagtc caagtgttgt acgacgttct ggacgaactt
    10561 caactgggac ttggtagtta gaaccaccaa cacgacgtgc acgtacttca agtacaggca
    10621 tgatgttttc catagctgtt tcaaatactt caagtgcatc gttgccagta gcttctttga
    10681 tttgctcaaa agcaccgtaa acgattgaag cagcagtacc acgtttacca tcaagcataa
    10741 cgcggttgat aagacgagta actagttgtg aattgtatag cggatctggc aatacgtcac
    10801 gttttggagc tctattttta cgactcattt ctctttatcc cctttcctta tgcttttgga
    10861 cgtttagtac cgtatttaga acgaccttgt ttacgatcgt taacacctgc agtatcaagt
    10921 gcaccacgga cgatatggta acgtacccct ggaaggtctt ttacacgtcc accgcgaaga
    10981 agcaccacgc tgtgctcttg caagttgtgt ccgatacctg ggatgtaggc agtaacttcg
    11041 ataaggttgc tcaaacgtac acgagcgaat ttacgaaggg ctgagttagg ttttttaggt
    11101 gtcattgttc caacacgagt tgcaacacca cgtttttgtg gtgaagaaac gtttgtttga
    11161 acttttttat gactattgta accaacgttc aaagctggtg atttagattt ttctactttt
    11221 gatttacgcg gtttgcgaac caattggtta attgtaggca tctacattct cctgtgtttt
    11281 tttatttttg gtgatgatac acttggtgac agatatcatc tgtgtgtact tttgcaacat
    11341 ttgtcagcac gtccctgtac actcttgaga gaccaaaagt aaaaagtacc gtctattatt
    11401 gtaacaaaat tttcccttgt ttgtcaagat atttttcttt tttattggta atgttagaga
    11461 tcaatttctg aataaaaata gctgggaaca catcatcttc ctaataatac ggcttggctt
    11521 atgtgacatt tttatctccg tcatttatac tgatatataa aatagtacag aaaacttctc
    11581 aaaagtaaga atttttttca caaatcaaag aaaacgcttg catattgttt tactacatgc
    11641 tatactgata tagaaattta ttgattggag aatcattatg agaaaaacac catctcacac
    11701 tgagaaaaaa atggtctaca gcatccgttc cctcaaaaat ggaactggtt ctgtccttat
    11761 cggcgcaagc cttgtcttgc ttgccatggc tacaccaact atctcatccg acgaaagtac
    11821 accaaccact aacgaaccca acaacagaaa tacaaccacc cttgcccaac ctcttactga
    11881 tacagcagct ggctctggta agaacgaaag tgatatttct tcacctagaa atgcaaacgc
    11941 ttccctagag aaaacagaag aaaaacctgc aacagagcca actacttcta ctagtccagt
    12001 aacaactgaa actaaggcag aagagcccat cgaagataac tacttccgta tccatgtcaa
    12061 aaaacttcct gaagaaaaca aggatgctca aggactatgg acttgggacg atgttgaaaa
    12121 accatctgaa aactggccaa acggagcttt gtccttcaag gatgccaaga aagatgacta
    12181 cggctattac ctagatgtca aattaaaggg agaacaagcc aagaaaatta gcttcctcat
    12241 caacaataca gctggaaaaa atctaaccgg cgataaatct gtagaaaaac tagttccaaa
    12301 aatgaacgag gcttggttag accaagatta caaggttttc tcttacgagc cacagcctgc
    12361 aggaactgtt cgcgtcaact actaccgcac agatggcaac tatgacaaga aatctctctg
    12421 gtactgggga gatgtgaaaa atccaagtag cgctcaatgg cctgacggaa cagactttac
    12481 ggctacaggc aaatatggcc gctatatcga cattcctctt aatgaagccg caagagaatt
    12541 tggattttta ttactagatg agagcaaaca aggagacgac gtgaaaatcc gtaaagaaaa
    12601 ttataagttc acagatttga aaaatcatag ccaaattttc ctaaaagacg atgatgaatc
    12661 gatttacaca aatccatact atgtccatga tatccgtatg acaggagccc aacacgtagg
    12721 cacttctagc attgaaagta gcttttcaac acttgtcggt gctaaaaaag aagatatcct
    12781 caaacactcc aacatcacta atcacctagg aaacaaggta actattaccg atgttgcaat
    12841 cgatgaagct ggtaagaaag tgacctacag cggagatttc tctgacacaa aacatcctta
    12901 tactgttagc tacaattccg accaattcac taccaaaaca agctggcacc tgaaagatga
    12961 gacatacagc tatgatggca aactgggagc tgacctaaaa gaagaaggaa aacaagttga
    13021 tttgaccctt tggtcaccaa gtgctgataa ggtttctgtt gttgtctacg acaagaatga
    13081 ccctgacaaa gtagttggaa ctgtcgctct cgaaaaaggg gaaagaggaa cttggaaaca
    13141 aactctagac agcacaaaca aactcggaat cacagatttc actggctact attatcaata
    13201 ccaaatcgag cgtcaaggta aaactgttct tgcactcgat ccttacgcta aatctcttgc
    13261 tgcttggaat agcgacgatg ccaagattga cgatgcccat aaagtggcta aagccgcctt
    13321 tgtagatcca gctaaactcg gacctcaaga cttgacttat ggtaagattc acaatttcaa
    13381 gactcgtgaa gacgccgtta tctacgaagc tcatgtgcgt gacttcactt cagatcctgc
    13441 cattgcaaaa gacttgacca aaccatttgg gacttttgaa gccttcattg aaaaactaga
    13501 ctatctcaaa gacttgggtg taacccatat ccagctcctt ccagtcttgt cttactactt
    13561 tgtcaatgaa ttgaaaaacc atgaacgctt gtctgactat gcttcaagca acagcaacta
    13621 caactgggga tatgaccctc aaaactactt ctccttgact ggtatgtact caagcgatcc
    13681 taagaatcca gaaaaacgaa tcgcagaatt taaaaacctc atcaacgaaa tccacaaacg
    13741 tggtatggga gctatcctag atgtcgttta taaccacaca gccaaagtcg atatctttga
    13801 agacctagag ccaaactact accactttat ggatgccgat ggcacacctc gaactagctt
    13861 tggtggtgga cgcttgggga caacccacca tatgaccaaa cggctcctag ttgactctat
    13921 caaataccta gttgatacct acaaagtgga tggcttccgc ttcgatatga tgggagacca
    13981 tgacgccgct tctatcgaag aagcttacaa ggctgcacgc gccctcaatc caaacctcat
    14041 catgcttggt gaaggttgga gaacctatgc cggtgatgaa aacatgccta ctaaagctgc
    14101 tgaccaagat tggatgaaac ataccgatac tgtcgctgtc ttttcagatg acatccgtaa
    14161 caacctcaaa tctggttatc caaacgaagg tcaacctgcc tttatcacag gtggcaagcg
    14221 tgatgtcaac accatcttta aaaatctcat tgctcaacca actaactttg aagctgacag
    14281 ccctggagat gtcatccaat acatagcagc ccatgataac ttgaccctct ttgacatcat
    14341 tgcccagtct atcaaaaaag acccaagcaa ggctgagaac tatgctgaaa tccaccgtcg
    14401 tttacgactt ggaaatctca tggtcttgac agctcaagga actccattta tccactccgg
    14461 tcaggaatat ggacgtacta aacaattccg tgacccagcc tacaagactc cagtagcaga
    14521 ggataaggtt ccaaacaaat ctcacttgtt gcgtgataag gacggcaacc catttgacta
    14581 tccttacttc atccatgatt cttacgattc tagcgacgca gtcaacaagt ttgactggac
    14641 taaggctaca gatggtaaag cttatcctga aaatgtcaag agccgtgact atatgaaagg
    14701 tttgattgcc cttcgtcaat ctacagatgc cttccgactt aagagtctcc aagatatcaa
    14761 agaccgtgtc cacctcatca ctgtcccagg ccaaaatggt gtggaaaaag aggatgtagt
    14821 gattggctac caaatcactg ctccaaacgg cgatatctac gcagtctttg tcaatgcgga
    14881 tgaaaaagct cgcgaattta atttgggaac tgcctttgca catctaagaa atgcggaagt
    14941 tttggcagat gaaaaccaag caggatcagt cggaattgcc aacccgaaag gacttgaatg
    15001 gactgaaaaa ggcttgaaat tgaatgccct tacagctact gttcttcgag tctctcaaaa
    15061 tggaactagc catgagtcaa ctgcagaaga gaaaccagac tcaacccctt ccaagcctga
    15121 acatcaaaat gaagcttctc accctgcaca tcaagaccta gctccagaag ctagacctga
    15181 ttctactaaa ccagatgcca aagtagctga tgcggaaaat aaacctagcc aagctacagc
    15241 tgattcacaa gctgaacaac cagcacaaga agcacaagca tcatctgtaa aagaagcggt
    15301 tcgaaacgaa tcggtagaaa actctagcaa ggaaaatata cctgcaaccc cagatagaca
    15361 agctgaactt ccaaatacag gaatcaaaaa cgaaaacaaa ctcctatttg caggaatcag
    15421 cctccttgcg ctccttggtc tcggtttctt actaaaaaat aaaaaagaga actaaactag
    15481 ccctcctata gaaaaatccc ccaagcatta tagctcgggg gattaatttt cgtacaatat
    15541 ttgttgtcct aataaacttg attaggattt tttattaagc ctctttcata gcaaaataag
    15601 ctcgtacttt tggtgcaact tgtgttccga agagttcaat agctctcaga acctggtcat
    15661 gaggcataga accaagcggt atatgaagca tgaagcggtc caatcctaaa tcctctatca
    15721 tgcgaatcaa tttttcggcc acctgatctg gattgccaac aaacatggcg ccatttggcc
    15781 ctacctgctc caaatattgc tcataacgca attcctgcca gtgcggacgg tctttggaaa
    15841 tagcatccac cacttgctta gtcggatgga aataatcttt caccgcctgc tcaccatctt
    15901 ccgcaatcca cccccaagaa tgggctccca ctttcaagtc tttgtcagca tggcccgctt
    15961 cgcttccaat ctcacgataa gcctgaatca actttttaaa ataacgtgga ttaccaccaa
    16021 taatagcata tacaatcggt agaccagcct gagcaatctt cactgttgat tcgacatgac
    16081 cacctgtagc tatccacaag ggcaatttgt cctgaactgg acgaggataa acttctttac
    16141 cagcaatcgt ttgagtcaat cgaccttgcc agtctaactt ggtcttttca ttgactaact
    16201 gaagcaagtc taatttctca tcaaaaagag agtcgtagtc tttcaagtca taaccaaaca
    16261 gagggaaaga ttccgtgaaa gagccccttc cagccataat ctccgatcgt ccatctgaca
    16321 aagcatcgat agtggcatac tgttggaaca aacgaatcgg gtccatgctt gacagaatgc
    16381 tgactgcact ggtcaaacgg attttcttgg tattgactgc cccagcggcc aggacaatct
    16441 ctggggctga tactgcaaaa tccgcccgat ggtgctcgcc aatcccatat acgtccaaac
    16501 caaccttgtc agccagctca atctctgcca ccaactggcg aatgcgttca gcatgactgt
    16561 aagtttgtcc agtcccttca agctccgtta tttccccaaa tgttgaaatt cccaattcta
    16621 ccattgtgat tctccttgtc tatctctgta cttcaatttg aaaaattatt ctaatactca
    16681 atgaaaatca aagagcaaac taggaagcta gccgcaggtt gctcaaaaca gtgttttgag
    16741 gttgtggata gaactaacga agtcagtaac catacctacg gcaaggcgac gttgacgtgg
    16801 tttgaagaga ttttctaaga gtataacacg aatcttgagt acaagcaacc aatttgctca
    16861 caagaaaaag cctagataac tagacttttt tagcttattc taccgttact gacttggcaa
    16921 ggttacgtgg tttgtccaca tcgaggccac ggtggagggt tgcaaagtaa gcgactaatt
    16981 gcgtcggtac gaccattgaa attggtgaga ggtatggatg tacggtcgta aggacgatat
    17041 cgtcggtatc tttggctaca ttctcttctg cgatagtgag gactttggca ccacgggctg
    17101 cgacctcttg gatatttcca cgagtatggt tggcaagaac tggatctgac aagagagcca
    17161 aaacaggcgt tccttcttca atcaaggcaa tggttccgtg cttgagttct cctgccgcaa
    17221 aaccttcaca ctggatataa gaaatctctt tgagtttgag acttgcttcc atggctacgt
    17281 agtaatcttg accacgtccg atgtaaaagg cgttacgagt tgtttcaaga agttcacgaa
    17341 ccttggcttc aatggtttct ttctctgaaa gagttgattc gatagactga gctacgattg
    17401 acaattcatg aaccaggtca aaggcttgcg ctttagcatt accatttgct tctccgactg
    17461 cttttgcaag gaaggcaagg gctgcgattt gcgctgtata ggctttagtt gatgccacgg
    17521 caatttcagg acctgcgtga aggagcatgg tatagttggc ttcacgtgag agggttgaac
    17581 ctggaacgtt tgtcactgtt aagcttggaa ttcccatttc attagccttg accaaaactt
    17641 gacgactatc cgctgtttca ccagattggc tgataaagat gaagagtggt ttcttgctga
    17701 gaagtggcat accgtagccc cactcagatg agattccaag ttcaactggt gtatctgtca
    17761 attcttccaa cattttctta gaagcaaatc ctgcatggta agatgttcca gctgcaagga
    17821 tgtagatgcg gtctgcgtct tgaacagcct taatgatatc tgggtctacg acaacttgac
    17881 cagcctcatc tgtgtaggct tggatgagtt tccgcataac agttggttgc tcgtcaattt
    17941 ccttgagcat atagtaaggg taagttccct taccgatatc tgacaagtca agttcagcag
    18001 tgtagctagc acgctcacga cgatttccat catagtcttg aacttccaca ctatcagcct
    18061 tgacgattac caactcttgg tcatggattt ccatgtattg gttagtttca cgaatcatag
    18121 ccatggcgtc tgagcagacc atgttatagc cttctccaag accaatcaaa agtggtgatt
    18181 tatttttagc tacgtagatg acttcaggat cttgtgagtc aaccaaggca aaggcataag
    18241 aaccacggat gatgtgaagg gcttttttga aggcttcaag aactgagagc ccttcttctt
    18301 ccgcaaattt tccaatcaaa tgaacggcta tttcagtatc tgtctgcccc ttgaagtggt
    18361 gacctgcaag gtattcttcc ttgatttcaa agtagttctc aatcacccca ttatgcacca
    18421 agacaaaacg ttctgtctca gagcggtgtg ggtgagcatt gtcctcagtt ggttttccgt
    18481 gagtagccca acgagtatgt ccgataccag ttgttccctc aacaccagct gtcttggcag
    18541 acaattctgc aatacgacca acagccttca ccaaatggtt atcagcacca tctaggacaa
    18601 aaattcccgc agaatcatag ccacggtatt caagcttttc aagcccttga atcaaaatat
    18661 cagttgcatt tgtgtttcca acaacaccaa caattccaca catagtatat acgacacagg
    18721 caagctgtgc tttctcctta aaattggtat agtctaattc atcttttata gaatcagcaa
    18781 aaacagtata tacttgtttc tttcacttgt caagagtaaa aattggtata gttcaaatta
    18841 agctcctgta agcataaaaa ctctgaccga ttgggataat cagtcagagt cctttttaaa
    18901 atccattatt atcgcttaat tctttgaacc agtggcctga tttcttcaga cgacgttctt
    18961 gcgtttccaa gtctaattcg accaaaccat agcgattttt atagctgttg agccatgacc
    19021 agcagtcaat aaaggtccaa atcaagtagc ccttacagtt ggcaccatct tcaatggcac
    19081 ggtgaagttc acgaagatga ccttttacaa agtcaatacg gtaatcatct tgaatcattc
    19141 catcttgacg gaatttttct tccccttcaa cacccatacc attctcagtc aacatccact
    19201 caatattgcc ataattttcc ttgatatttt gggcgatgtc ataaatccct tgctcataaa
    19261 tctcccaacc acggtgagaa ttgattttac gtccaggcat cacataaggc tcgtaaaaat
    19321 gttctggtaa gagtggacta tctggatgct tagcaaatcg aggagccata acacgcaaag
    19381 gttgatagta gttcacacca aggaagtcca ccgtattatc acgaatgagt tccaactctt
    19441 cctctgtagc atcaggtaaa agaccgtgtt catgcaagat ttctaccaac tcctgtggat
    19501 aagtccccaa gacagatgga tctaagaaag attgggcctg aaaaagggcc gcaatacgag
    19561 ctgccttgac atcagcagga tgctggctac gtggataagc cggtgtcaag ttgaggacaa
    19621 tcccaatctt ggaatcaggc aaaagttcat ggcaagcctt aacagcccgg ctgctggcca
    19681 attgtgtatg ataggctacc ttaacagctg cctctgcatc caccttatgt ggataatggg
    19741 catcataaaa ataaccaaat tctacaggaa cgatgggctc gttaaaggta atccattgat
    19801 ccactaaatc tccataagtc tcaaaacaaa aacgagcata gtcttcatag gctgagactg
    19861 tcgccttatt ttcccaacca tcaccatcct cttgaagggc aaaaggtaaa tcaaaatgat
    19921 agagattgac taacagacga attcctttag ccttaatagc ctcaaagacc ttacgataaa
    19981 aatccacacc ttgagggttg actttcccac agccttgtgg aaaaatccgt gaccactgaa
    20041 tagaagtccg aaagactgtg tgaccagtct ctaacaaaag ctcaatatcc cgctcccaat
    20101 tttcataaaa agtcgatgtc ttatctgaac caatcccatt atagtaacga tttggctcca
    20161 cttggaacca gtaatcccag agattgtctc ccttaccgtc accagctaca cgtccttctg
    20221 tctgcggtcc agaagtagag gatccccaga caaaatcctt tggaaatctt agcataacat
    20281 ttacctcttt atctactcat ttctcccatt atacagaaaa aacaaggtaa aaactagtta
    20341 cattttttcc ttgtttttct tctgattata gtttttattt cttgcttagg atttcaagcg
    20401 tttcaagcac gttatctgca tgaacctcaa tggtgtcacc agttgccttg atcttaactt
    20461 ctacaatgcc atcggccgct tttttaccaa cagtgatacg gattggaaga ccaatcaagt
    20521 cactatcgct aaatttaaca ccgacacgtt cgttacggtc atctgtcaag acttcataac
    20581 cagctcccat caagcttgct tcaagttttt ctgtcaaggc ttgcgcttct tcatccttga
    20641 cattaacagt aatcaaatgc acatcaaatg gtgccaattc tttagggaaa ttgattcccc
    20701 aagcgtaacg gtattcacct tttggcgttt tgttaacaaa gaggcgagcg tgttgctcca
    20761 tcactgctga aagaagacgg ctgacaccga taccgtaaca tcccatgatg attggcacag
    20821 cacgaccatt ttcatccaag acatctgctc ccatgcttgc tgaatagcga gttccgagtt
    20881 tgaaaatatg accgatctca ataccacgcg caaagttaag gacaccttgt ccatctgggg
    20941 aaatttcacc ctcacgaact tcacggatat ccacatattc tgcagtaaaa tcacggcctg
    21001 ggttcacacc agtcaagtgg tagccatctt cgttagcacc gacaactgca ttgcgaacat
    21061 cttgcacctt acgatctgca ataattttaa tattctctgg caaaccaact ggtccaagtg
    21121 aaccaaatcc tgcttgaaca acattcgcca cttcttcttc gctagcaacg tcaaagaaat
    21181 ctgctcccaa gtgatttttc aacttgactt cgttgagttg gtcatttcca actagaaggg
    21241 ctgcaacaag ctcaccatct gcaatgtaga agagggtttt aatcgtttgt tcttctggaa
    21301 cattgaggaa agctgcaact tcatcaattg atttaacatc tggcgttgca acacgagtaa
    21361 cttcttcttc agcgacaaca cggttgcttg gtttgtactc gtttgttgcc atttctaagt
    21421 tagctgcata gctagactca cttgagtaag caatggtatc ttcaccagag actatccatt
    21481 tgagcaattc tgccttgatt tcttcttgca cttctgcagg aatttcgtca aatgaggcaa
    21541 ctgacttgtc caagacaacc cagcggtcaa ggtctgtacg agcagatgta atggccataa
    21601 attcttggct atccttacca cccatggctc caccgtcacc aataatagcc ttgaagtcta
    21661 aaccactacg agtgaaaata cgctcataag ctgctttgta ctcatcataa acactatcca
    21721 aactatcata gttagcgtgg aaactataag catccttcat gataaactca cgtgtacgaa
    21781 gaagtccatt acgcgggcgt ttttcatcac gatacttggg ctgaatttga taaaggttga
    21841 gtggcaattg cttgtaagat ttaacagaat cacggacaat agctgtaaag gtttcttcgt
    21901 gagttggacc taagataaag tctgattttt cacggttttt tagtttgtaa aggtcttcac
    21961 cataggtttc gtaacgacct gattcacgcc acaattctgc actaagaagg gctggagcca
    22021 acatctcaac agcaccaatc ttttcgaatt cttggcgcat gatgttttta gctttttcaa
    22081 tcacacggtt ggcaagtggt agataagaat aaacacctgc tgaaacttgg cgaacataac
    22141 cagcacgcaa cataagagca tggctgataa cttgagcatc gcttggcatt tcgcgaagcg
    22201 ttgggatagg cattttactt tgtttcataa tattcctcga ttatctaaaa aagagtcgca
    22261 taatgtcatt ccaagtcaca gcaatcatca agacaaccat gatgaccact ccggccaagg
    22321 tgacataggt ttcaatttct tgtttcaatg gtttgcggcg gatggcttct aggatattga
    22381 gcacaatctt accaccatcc aaggctggaa tcggaataag attaaaaatc ccaatattga
    22441 tggaaatcat tgccaagaag tacaagatat tttcaattcc atttttagca gcatcactac
    22501 ttgccttaaa gatagcaaca ggtccaccca acttgttcaa atctggttgg aaaatcagat
    22561 ttttcagagc tgagagaatt cggagagctg agtcagcagc agttgtaaaa ccacctacaa
    22621 acatggatag aaaatctgac ttaccccccg gttgaacacc tagaaggtaa cgaccttgac
    22681 tatctttggg tgtaacagtg acttgtttgt cactcccctt ttcagaaata gtcacatcca
    22741 aagtcggtgc cgtcttatct ttggtttctg tttccacagc ttggatcaag ctttcccagt
    22801 tgctaacctc atgtgagcca atcttggtaa tttgtgccgt ttctggtact cctaccttgg
    22861 ccaaggcacc ttggggcatg atatggaact gattggtatc aacatctctg acaccaccct
    22921 gcataaagat taaaacccaa aaaacaacga cacctaagat aaaattgttc ataggacctg
    22981 caaaattggt aatcagtttg ccccagatag tcgcattttg atattgaaca tctaaaggtg
    23041 caatccgaac ctcagtacca tctgcttcca caaccgttgc atcgtgatcc actgcaaatg
    23101 ttttttcttc ttccagaacc aatcctttga taaagagctt gtcttcaaaa tcaaactggg
    23161 tcacctgcat agggaggact gtttgatcca attttttacc tgagagattg atgcgtttaa
    23221 ccttaccatc atcagcaagt gtcaaactaa caggcgttcc tgtcttgatt tcagttgtat
    23281 catcacccca accggccatg cggacatagc cacccagagg caagattcga atggtatagg
    23341 ccgttccatc cttgccaatg tgagcaaaaa ttttaggtcc cataccgatg gcaaattcac
    23401 gtactaaaat ccctgatttc ttggcaaagt agaagtgccc gaactcgtgc accactacaa
    23461 taatcccaaa aactagaata aaggttaaaa ttccaagcat agtgtttcct ccgtcttttg
    23521 attaaaagag tccaaataag tgcatgattg gaaatacaag caacatacta tcgaaacgat
    23581 ccaaaacacc accatgtcca gggataaatt tcccagaatc cttaacacca aaatgacgtt
    23641 tgatcgaact ttctagtaaa tcaccaaatt gtccagcaat gctaaagaaa atagcaaaga
    23701 ctgacatctt gtaaattcca tatggaagag caactgtact gtcaactatc ataaagataa
    23761 tggttactaa aattgctcct aaaataccac ccaaggcacc ctcaagggtt ttattaggcg
    23821 atacccttgg tgctaacttt cgtttcccat agttcatccc aacaagatag gcaccactgt
    23881 ctgtcgccca gacgatacac aaggctaaga gagccttgtc caaacctgca acacgagcat
    23941 ctagtaaagc attaaatcca aagcccacgt agaagctcat agcaagaggg aaaaccgcat
    24001 cctcaatcgt ataagacttg ctaaaaacgg tcgttcctaa catgattgaa atcaaaacac
    24061 tataggcaac cacattccca tcaactggca aaaaagtcag gtaattctcc aagggaatgg
    24121 tcaatgcaaa ggttgcaaag agggtcaaga ggccctccat cgtcatggtc tctagacctc
    24181 tcatcttcaa aagttcatgc atggctagca tggctatgat tccgattgct atctgaagca
    24241 agaggccccc aatcattaaa attggtagga aaatagccag ggcaatccct gcaaacaagg
    24301 ttcttttctg taaatcctgg gtcatatttc ctcctaaact cctccaaatc ggcgatgacg
    24361 acgattatag gcaagaatag cttcctgcaa ggccgcttcg tcaaaatcag gccataaggt
    24421 gtccgtaaaa taaagctcac tataggctcc ctgccatgga aggaaattgc tcaaacgtaa
    24481 ttctccacta gtacggataa tcaagtctgg gtctcgtaag tccttaggca aatgctgagt
    24541 aaagagatag ttaccaatca attcctctgt gatgtcacct gggttgattt tggcatctaa
    24601 aacatcctgg gaaatcaact taagcgcctg tgtaatctca gcacgtccac catagttaag
    24661 agcaaaatta agaatcaatc ctgtgttgtt cttagtcaat tcctcagcct tggttaaagc
    24721 ttcaaaggtt tgcttaggca ggcggtctgt ctccccaatc atttgaatct taacattatt
    24781 cgcatgtagt tccgggacat aattatcata aaactctact ggcaagttca tgataaactt
    24841 gacttcctga tctggacggg tccagttttc cgtagaaaaa gcatagaccg taataacctt
    24901 gacgcccagt ttgttggctg ccttggtcac ggtttgcaat gcttccatgc ccgccttatg
    24961 tccaaaaact cgcggttgca tacgtttttt agcccaacgg ccattgccat ccatgatgat
    25021 gccgatatga gcaggaacct gtgtcggaac ctctacttcc acagccttat ctttcttaaa
    25081 aaatccaaac atgatcttat tcctattcaa aaatctatcg tttcattata ccatatttcc
    25141 ccattttctt ctatcactaa gctatttatt ctcaggcacc atgcccattt ttcaaaaaaa
    25201 taagccgcct gattgggcga ctttattttt atagggagat tattatgaaa aagttttagg
    25261 agtttaagtt aaggtcttct taacttatga acttagtgta cactccctag cttaaagttt
    25321 ccttaagtat ttttaaaaat caaatttttc catttctcct gccaattttt cttggataaa
    25381 cgtgtttgat agagttccat tcggtcttca ttttctaaga aatgaggagt tggacgaact
    25441 tgaaaattca aaatatcctc caaaccataa ggtgcataga gttcaaaatc tgattcttca
    25501 ttcaagcgca gtccaactgc cgtacaccgt tctggatact tactcatagc atcacgagaa
    25561 ctggtatagg aagcagtgtg aggactgtgc tggtgcatat agacctgatt tttcaattcc
    25621 cactggtact gaggaaaatc ctctctcagc tttttctcca gtaataaggt ttcctcataa
    25681 gaaaaatctg gatcaaagaa aatcacatct atatctgttt catgatcaaa aggggatttg
    25741 tctgacaaaa gattccagat gaaatttctg acagaacctg ctgccaacta cgagtctttc
    25801 aaaccaaggt ctcggatgat cgtcagaatg gccatcatat ctggattttc tctaaaagcc
    25861 tctaagattt cttgcttatt tttcactgta ttcataacct aagtgctcat atgccttagc
    25921 agtcgccacc cgtccagacc gtgtccgcat gataaaacct ttttgaatca agtaaggctc
    25981 atacatgtct tcaactgtct cacgctcttc ggcgatattg acagaaagag ttcctagacc
    26041 aacaggtcct ccactgtaca tctcaatcat ggtacgaagg attttttgat ccacatagtc
    26101 caaaccttca tggtcaacat ccagcatagt caaagcctta tcggtaataa tatcatcgat
    26161 taccccattc cccattatct gggcaaaatc gcgcacgcgc ttgaggagac gattggcaat
    26221 acgaggggtt ccacgactac gtagggccaa ctcagatgct gcctcatgag tgatttccat
    26281 ctcaaaaata tctgccgtcc gctcgacaat ttctgtcaag tcagcatggg cataatactc
    26341 catatgacct gtaatcccaa aacgtgcccg tagtggattt gagagcatac cagcccgagt
    26401 cgtcgcacca atcaaggtaa aaggaggcaa ctccaaatga acactgcgac tgccttcacc
    26461 agccccaatc ataatatcga tgtagaagtc ctccatggca ctataaagca cttcttccac
    26521 tgacatgggt aagcgatgaa tctcgtcaat aaagaggaca tctccaggct ctaactcatt
    26581 caaaatcgct accaaatcac ccgctttttc gataacagga ccagacgttt gcttgagatt
    26641 gactcccagt tcattggcaa tgacaaaagc catggttgtt ttcccaagcc ctggagggcc
    26701 aaataagagc acatgatcca gcgcttcatc ccgcatttta gcggcttcga taaagatctg
    26761 aagctgatcc ttaaccttat cctgaccaat atattcacgt aaatactgag gacggagcgt
    26821 gcgttctact aactcctcat cacccatcat ctcattatct aaaattctac tcatggctct
    26881 attatatcaa aaaaacaagc cacaaacaaa aaagccacct gattgggtga ctcctaagtt
    26941 tagcacttat gtggtataat attatacggc acttctacac cgcctacgaa aggaggtgag
    27001 atagcccatg atggaattag tactcaaaac tatcatcgga ccaattgtgg tcggtgtcgt
    27061 tcttcgtata gtcgataaat ggctaaacaa ggacaaatag tgtcaaaaaa gacctcaagc
    27121 ttatttggtc gtgagcttgg ggtcttttct agcctatgat atagaactag tactcaattc
    27181 ctttttatta tcccatagtt cacgaatttt gtcaaaggtt tacattttct tcaaccgctg
    27241 tacgacaaga cggttaagat taagagaacg ttagggattc tatcaatttc atagaaattt
    27301 tgatttcgta aacgaagaga caatcttaca tgtcacttct catttaatac gccactacta
    27361 gacaagcaaa atcattatta cagtagttcc agttcttcaa ttaacagtca cttacaatca
    27421 aattgagttt gaactagctg aagcgaccac agacctattt cttagttata ttcgctaaaa
    27481 aagtccccgc caattccccg accaaaatcc gaaaaatacc gaaaaatatc gaaaaattat
    27541 ttttagaata gtccccaaaa gcctgaaata gagctaaaaa actccacctg attgggtgga
    27601 gttaagggag attattatga aaaagaaaag tttaggattt tattaaataa agttaggagg
    27661 tctttattta ataactacat gatacaagac gaaacttaaa actagcttaa cttttctaaa
    27721 attttactat tttgcaaaaa atttctatca ccagcacctc accacgcaaa aaagccacct
    27781 gattgggtgg cttcattagg agattgtgat gaaaaaagtt taggatttta ttaaataaag
    27841 ttaggaggtc tttatttaat gattatataa tactagacca tccttaaatt ttgcttaaga
    27901 aaaaacaagt tttgttattt tttacgattc atccaagtca tccctatcca attataggtg
    27961 gataagattt caaagcccat agaacgatta aatcccacgt ttttttctgt ctgttctgtc
    28021 gccagctgga cttgataggc ctctttaaaa tttcctaaag cctgtttcat caaggagcta
    28081 ccaatccctt ggcgctgata gctagacaaa acaatcaaat cctgtacaaa aactgatgaa
    28141 aaaccatctc caaccaaacg aatcaagccc acaacagcat caccatcaag tgccagataa
    28201 attattaatg aatgatacaa ggtctactcc agcatctgag gttgatttgt ataatttgtc
    28261 caaccgacag cctgatagag atgcaaaaca tcctcgaact tgacgatttc ttgctttcta
    28321 atagtgatca tgtcaacacc tcttaaaact ctctcaagct cttgtactgc tgtccatttt
    28381 tatcaaaatt ttcaggacgc aaccatgttt ccaaacgatc tttgactttg ggccagtcct
    28441 tatcaatcat agacaaccaa tccatatctc tcgtacgccc cttataaacc actgcctgac
    28501 ggaaggttcc ttcataaata aagcccaaac gctccgcagc acgtctggat ggcaggttaa
    28561 gagcatcgca tttccactca taacgacgat agttaagctc ttcaaagaca tagcgagcca
    28621 gtagatactg ggcttctgtc cctatccgtg tccccctgag ttttggagaa aaagtgacag
    28681 ctcccacttc tattactccg ttactggtca atacgcatga gagaaaaagt tcccaaagcc
    28741 ttaccagttg ccttgtctat gattgcatag taaaaacggt ccttacgacc aacatctgat
    28801 ttaaaaggct gaccagttcc tcaatgtctg ctactggctc ctgaaagagg taggtccaca
    28861 tctcctgagg agtatcagga ccataaacag ctagcaaatc ctccgcatgc ttttccactg
    28921 aaagagcctc tatcctagca taacgccctt ctaagagatc aataaaagtc agttcacctg
    28981 gtgtataacc ttccattgac tcaccaatca tctgaccata ttcgtttact ggtataactt
    29041 tctccttgtt tcgcttttca aactttatag ttgcccatag tatagcgtat tgaaataaga
    29101 tgagaacaaa tcgattggga aagtaaaatt aatttctata aatgttttag caattgtttc
    29161 gtactatttt agattcagtc tactatatat catactttca taagaaggtt caaaaaatcc
    29221 tccagattct actctgaagg attcctatct tatttcacaa caatgttaac taatttagtt
    29281 ggcttcaata gtccagtgga ctattgaagg tggcagatag agctaataaa ctcgttattt
    29341 aacgacgata ttaacgagtt tattcggtac cgcaattact ttcacgattt ccttaccgtc
    29401 aatttctgct ttgacttttt catcagctaa agcgatttct tgtaattctt cacgtgatat
    29461 atctttagca accatgagtt tggcacggac ttttcctttg atttggacaa caatttcaat
    29521 ttcatcttca accaatttgc tttcgtccca agttggccaa gctacataag agattgactc
    29581 acctgtttct gcgactgttt gccagagttc ttctgccaag tgaggtgcaa atggtgcaat
    29641 caattgaata aagcctttgg catagtcaac ataaagctta tcttccttgt tagcagcatt
    29701 gacaaagacc ataagttggg caatagctgt gttgaatttg agagactcaa tttgctcagt
    29761 aacagctttg actgtttcgt tgtaaacctt gtcaagagca ccattgtttt ccgcaaggat
    29821 ttctttactt gtaatcaaac ggtaaactcg gtcaaggaac ttacggcttc cttccaaacc
    29881 ttcttctgac caagcaatcg aagcatcgag tggtcccata aacatttcat aaacacgaag
    29941 ggtatcggca ccgtattgtt ccaccacatc gtctgggtta acaacgttct tgagcgattt
    30001 agacatcttg gctggcgctt gctccaactc ttcccctgtt tctacatgaa agaaggaacc
    30061 atcacgtttt tcaaccttgt cggttgccac aagagcacca cggtggtcac ggtagcttgt
    30121 tcccaaaatc atcccttggt taaagagttt ttggaatggt tccttagtcg gaacaacacc
    30181 gaggtcatag aggaatttat gccagaaacg agcataaagc aagtgaagta cagcatgttc
    30241 cgcaccaccc acgtagatat ctactggcaa ccattgtttg aggaggtcct catcagccaa
    30301 tttctcagta ttgtgcgggt caatatagcg gaggtagtac cagcttgaac cagcccattg
    30361 tggcatggtg ttagtttcac gacgaccttt gacaccatct tcacgagtca cttcaagcca
    30421 atctgtcaag ttagctagtg gactttcacc agtacctgaa ggacggatat ccttggttac
    30481 aggcaagaca agcggcaatt cagtttcagg aacagctgtt gaagttccat cttcccaatg
    30541 aatgattgga attggctcac cccagtaacg ttgacggcta aagagccagt cgcggaggcg
    30601 gtaggtaacc ttctcctgac cacagccttt ttcttccaag caagccacaa tcttggcaat
    30661 agcgtcttct ttattcaatc catctaggaa gtctgaattg acatgcaggc catcctctgt
    30721 gtaggcagct tcttcgacat ttccaccttc aagtacttcg acgattggaa ggtcaaattg
    30781 tttggcaaat tcccagtcac gttggtcgtg ggcaggcaca gccataaccg cacctgttcc
    30841 ataactagca agaacatagt ccgcaatcca gattggcatt tccttaccat tgacagggtt
    30901 gatggcatag gcacctgtcc aaacaccagt tttttcctta gcaaggtctg tacgaaccaa
    30961 gtcagactta aggctggctt ggtgtttata gtctgctaca gcttctgctt gctctgaact
    31021 tgtgatagcg tctactaatt catgttcagg agccaagaca gtgaaagtcg caccgaaaag
    31081 tgtgtccgga cgagtagtaa agactgtaaa ttccttgtct gttcctttta ctttgaaagt
    31141 tacattggca ccagttgatt taccaatcca gttgcgttgc atatccttga tagactctga
    31201 ccaatctagt tcatctaagt cattgagcaa gcgctctgcg taagccgtga ttttgagcat
    31261 ccattggcgc attggtttgc ggacaactgg atagcctcca cgctcagaag ttccgtcagg
    31321 aagcacttct tcattggcaa tggcagttcc caattcctca acccagttta ctggcacttc
    31381 agcttcatag gccaagcctt tttcgtaaag cttggtgaaa atccattgag tccacttgta
    31441 gtagtttgga tctgttgtgt tgacttcacg atcccagtca taagaaaatc caagcgcatt
    31501 gatttgacgt ttgaagttgg caatgttttc cgctgtaaat tctgctgggt cattaccagt
    31561 atccatagcg tattgctctg caggcaaacc aaaagcatcc caacccattg ggtgaaggac
    31621 attgtagcct tgcgcacgtt tgtaacgact gaggatatcg gttgcagtat aaccttctgg
    31681 gtgtcctacg tgcagaccaa ctccagacgg ataagggaac atatcaagcg cataaaactt
    31741 aggttttgat gtatctgttc ctgtcttaaa tgtatgatgt tctgcccagt agccctgcca
    31801 cttaggctca atttctttat gattataaaa actcatggtc tctctccaat tttgtgatgt
    31861 tactattata ccatttttga gggaatttga aatgtgttta aagaaaaaac tgtatactgt
    31921 atctcattaa ttttgatgac tatgaattgc tctatctccc actttttatc ccattgttat
    31981 gcagtaaatc aaggagtaag tcaagacgct tatctcgtat agcacaaaat acttatttta
    32041 gaccgaagat aaaactggaa tgct
//
LOCUS       DBEJKC010000024        29043 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.024, whole genome shotgun sequence.
ACCESSION   DBEJKC010000024 DBEJKC010000000
VERSION     DBEJKC010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 29043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29043
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.024"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..414
                     /locus_tag="ACL3G6_001090"
     CDS             <1..414
                     /locus_tag="ACL3G6_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HGR0545635.1"
                     /translation="ALPTDYDEKIGSFNTYEIEQTVSKILRVKPNGKIILKSTVPIGF
                     SNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVVGDETVEGRKIAELFLSISTHS
                     TANIKNVMLVSPTEAEAIKLFSNTFLALRVAFLMN"
     gene            456..554
                     /locus_tag="ACL3G6_001091"
                     /pseudo
     CDS             456..554
                     /locus_tag="ACL3G6_001091"
                     /inference="COORDINATES: protein motif:HMM:NF013175.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
     gene            585..935
                     /locus_tag="ACL3G6_001092"
     CDS             585..935
                     /locus_tag="ACL3G6_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP binding domain-containing protein"
                     /protein_id="HGR0545636.1"
                     /translation="MIEAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKE
                     SAILSIINELLIVGIKILVYEPNLNVSIDNVIIEKNFELFTKQSDLIVANRWDRGLEA
                     YKDKVYTRGIWIRD"
     gene            1330..2193
                     /locus_tag="ACL3G6_001093"
     CDS             1330..2193
                     /locus_tag="ACL3G6_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGR0545637.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQGQMAETYRRLNAIVIKNALHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKSGFLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKVLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLIALFE
                     LRLQQYKKLID"
     gene            2476..2676
                     /locus_tag="ACL3G6_001094"
     CDS             2476..2676
                     /locus_tag="ACL3G6_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HGR0545638.1"
                     /translation="MLNLQFAETMELTEAELEIVYGGEFGNNAVIPAGAWGGFGTPWS
                     ITNFWKKNFNDRPDFDSDRRRY"
     gene            2743..3408
                     /locus_tag="ACL3G6_001095"
     CDS             2743..3408
                     /locus_tag="ACL3G6_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0545639.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            3480..4706
                     /locus_tag="ACL3G6_001096"
     CDS             3480..4706
                     /locus_tag="ACL3G6_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0545640.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICMINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTTLYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(4981..5133)
                     /locus_tag="ACL3G6_001097"
     CDS             complement(4981..5133)
                     /locus_tag="ACL3G6_001097"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545641.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVADRTDEVSSKHCFEVVDRTDEVS
                     NTYTAR"
     gene            5204..5860
                     /locus_tag="ACL3G6_001098"
     CDS             5204..5860
                     /locus_tag="ACL3G6_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HGR0545642.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWHNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGDLLPNPEIFGLDFALVGMFIGI
                     FASQFQMMQRRISVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGMVLDGQ
                     "
     gene            5850..6173
                     /locus_tag="ACL3G6_001099"
                     /pseudo
     CDS             5850..6173
                     /locus_tag="ACL3G6_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
     gene            6277..7107
                     /locus_tag="ACL3G6_001100"
     CDS             6277..7107
                     /locus_tag="ACL3G6_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0545643.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            7261..8115
                     /locus_tag="ACL3G6_001101"
     CDS             7261..8115
                     /locus_tag="ACL3G6_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGR0545644.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            8215..9588
                     /locus_tag="ACL3G6_001102"
     CDS             8215..9588
                     /locus_tag="ACL3G6_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HGR0545645.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYHTHIELVE
                     ELIRSYE"
     gene            9581..10642
                     /locus_tag="ACL3G6_001103"
     CDS             9581..10642
                     /locus_tag="ACL3G6_001103"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HGR0545646.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGSSTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            10644..11336
                     /locus_tag="ACL3G6_001104"
     CDS             10644..11336
                     /locus_tag="ACL3G6_001104"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HGR0545647.1"
                     /translation="MESLIQTYLPNVYKMGWSGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAIPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(11365..11934)
                     /locus_tag="ACL3G6_001105"
     CDS             complement(11365..11934)
                     /locus_tag="ACL3G6_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGR0545648.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            12069..12683
                     /locus_tag="ACL3G6_001106"
     CDS             12069..12683
                     /locus_tag="ACL3G6_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGR0545649.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            12661..14331
                     /locus_tag="ACL3G6_001107"
     CDS             12661..14331
                     /locus_tag="ACL3G6_001107"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0545650.1"
                     /translation="MKNWRQNRMKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSR
                     EKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQ
                     LERKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDF
                     KPAGNSFAIPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIF
                     HIGETVDKESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLT
                     LRQTFANYQKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNI
                     HDIYQLELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLR
                     NNISDERETLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVE
                     NYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQ
                     ASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            14343..15629
                     /locus_tag="ACL3G6_001108"
     CDS             14343..15629
                     /locus_tag="ACL3G6_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR0545651.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFAIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLTSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            15681..16214
                     /locus_tag="ACL3G6_001109"
     CDS             15681..16214
                     /locus_tag="ACL3G6_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0545652.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            16292..16762
                     /gene="nrdI"
                     /locus_tag="ACL3G6_001110"
     CDS             16292..16762
                     /gene="nrdI"
                     /locus_tag="ACL3G6_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HGR0545653.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(17055..18317)
                     /locus_tag="ACL3G6_001111"
     CDS             complement(17055..18317)
                     /locus_tag="ACL3G6_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HGR0545654.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(18460..19413)
                     /locus_tag="ACL3G6_001112"
     CDS             complement(18460..19413)
                     /locus_tag="ACL3G6_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HGR0545655.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HTEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     gene            complement(19873..20331)
                     /locus_tag="ACL3G6_001113"
     CDS             complement(19873..20331)
                     /locus_tag="ACL3G6_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HGR0545656.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(20328..20768)
                     /locus_tag="ACL3G6_001114"
     CDS             complement(20328..20768)
                     /locus_tag="ACL3G6_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR0545657.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            21124..23073
                     /gene="mutL"
                     /locus_tag="ACL3G6_001115"
     CDS             21124..23073
                     /gene="mutL"
                     /locus_tag="ACL3G6_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HGR0545658.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(23398..23865)
                     /gene="ribE"
                     /locus_tag="ACL3G6_001116"
     CDS             complement(23398..23865)
                     /gene="ribE"
                     /locus_tag="ACL3G6_001116"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HGR0545659.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(23866..25071)
                     /locus_tag="ACL3G6_001117"
     CDS             complement(23866..25071)
                     /locus_tag="ACL3G6_001117"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HGR0545660.1"
                     /translation="MEYRKIQETLEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLIERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(25091..25726)
                     /gene="ribE"
                     /locus_tag="ACL3G6_001118"
     CDS             complement(25091..25726)
                     /gene="ribE"
                     /locus_tag="ACL3G6_001118"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004746 - riboflavin synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HGR0545661.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSINGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(25711..26811)
                     /gene="ribD"
                     /locus_tag="ACL3G6_001119"
     CDS             complement(25711..26811)
                     /gene="ribD"
                     /locus_tag="ACL3G6_001119"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HGR0545662.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(26946..27060)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            27217..27810
                     /gene="ruvA"
                     /locus_tag="ACL3G6_001120"
     CDS             27217..27810
                     /gene="ruvA"
                     /locus_tag="ACL3G6_001120"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HGR0545663.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            27820..28383
                     /locus_tag="ACL3G6_001121"
     CDS             27820..28383
                     /locus_tag="ACL3G6_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HGR0545664.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTETELEAMLENPAIIRNRAKLFATRANAQ
                     VLLQLQAEYGSFDAYLWSFVEGKIVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            28380..>29043
                     /locus_tag="ACL3G6_001122"
     CDS             28380..>29043
                     /locus_tag="ACL3G6_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0545665.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAI"
BASE COUNT         8407 a         5445 c         6108 g         9083 t
ORIGIN      
        1 gcgcttccga cagattatga tgagaaaatt ggtagtttta atacatatga aatcgaacaa
       61 acggtatcga agattctgag ggtaaaacct aatggaaaga ttattttaaa gtcaacagtt
      121 ccgatcggct tttcaaacaa attaaaaagg ctgtttgata caaaaaatat catttttgtc
      181 cctgaatttt tgagagaagg ttgttctata tatgataatt tatatccaag tcgcatagtt
      241 gttggagatg agacagttga aggaagaaaa attgcagagt tgttcctttc gattagtact
      301 catagtactg ccaatattaa aaatgttatg ttagtttctc ctactgaagc agaagcaatt
      361 aagctttttt ctaacacatt cttagctctc cgtgttgctt ttttaatgaa ctagattctt
      421 ttgctgagag gagaagctta aatgctgaag ttgtaataaa aggtgtttgt ttagatccaa
      481 gaattggaaa tttttataat aatccttctt ttggatttgg aggatattgt cttcccaaag
      541 atactaaaca attaaaaaaa gaatttatag aaataaatgc cccagtgata gaagcgattg
      601 atatttcaaa cacaaataga aaacagttca tagttaaaca aatattggaa cgaaagccaa
      661 agatagtagg aatatataaa ttggggatga aatataattc agataattac aaagagtcag
      721 ctattttaag tataattaat gaactattga ttgtcggtat aaaaatttta gtatatgaac
      781 caaatttaaa cgttagtata gataacgtaa ttattgaaaa gaattttgaa ctatttacaa
      841 aacaaagtga tctaattgtt gcaaatagat gggatagggg ccttgaagct tataaagata
      901 aagtttacac aagggggatc tggataagag attaactatt gatattaaaa aggcaataat
      961 ttataaaatt tgtacaaaaa aatgttaaat tttcacattt tcatagtata ctgtttaata
     1021 gaaagtaggt tctttgtaac cgctccatta taaaatcctt tcactcttcc ggtatactat
     1081 taggaaaaac ataactggag gatattttga gctcacacct catcgttcca gtggctgttc
     1141 cccaagctcg tgtactgccc aaaaaagtta gacattctat ttagaacgag gattgagttc
     1201 tgtattgtac aaggctcggt ccttttagag tcagcttaag gctggctttt ttaatcacca
     1261 aagtgtcaga atgttttgac aaatgaacac aaataatgat ataatatgca aaagctagga
     1321 ggtggtagga tgattgaaaa aatggaactg ggggaatttt acaaggaatt gcgtttggcg
     1381 agaaagctca agcagtcaga tgtggcttgt gctggactaa cagcttctca gctatccaag
     1441 ttcgaactag ggcagtctat gctgtctgcg gataagctca tactagccat ccaagggatc
     1501 aatgtgacct ttgatgagtt tgggcacaag ctcaacaact atcaagaatc tccacatatg
     1561 cagattggta gaaaggttgt ggatcgcttt gctcatcaag atatagctgg cttagagcaa
     1621 ctgttggagg aagtcgagca aggacagatg gcggagacct atcgtcgttt gaatgctatt
     1681 gtgattaaaa atgcactcca ttccttagat aaaagctatc cgctagcaga ggaggatagc
     1741 gagtttttga ctacctacct ctatgctatt gagtcttgga cctggtttga actctatctt
     1801 ttttgcaata ccatgccctt cttgagcaat caagatctga tctttttatc aacctctttg
     1861 cttgaaaaat ccaaggaatt taaagagttg gtacataata gactgtatat gaaaagtggc
     1921 tttctgaata ttatatcaga gctcatggag cgcaagcttt tctcctatat cccaatcttt
     1981 gaagccgagc tggagagtat gctccgtcca tacgatgttt ttgagaaagt gttgtggcag
     2041 tttttaaaga agatgagcat tttccttcaa actaagggaa gcaatcaaaa agagattgaa
     2101 cactttatcc aatctctgca agtattagaa aatccacaat taatagccct ttttgaattg
     2161 cgtttgcagc aatacaaaaa gcttatcgat tagttagaaa tggcaaaata ataatctcag
     2221 caacgatttt caataatgtt aaaatttgtt tcttcatatt tctccactcc tcattagtag
     2281 taactttatt ataccagaga agtaatcaaa ttcaccaaaa tcgcaaatct gaaatttcta
     2341 taagaaaaaa tatcaaatat gcgattttct aaaataagcc aattttcgtg ttatactgta
     2401 cttgtaaagc acttgaagca aatcctaggt cgcagaagtg gtttacaaat gaagataatt
     2461 gaaggagtgt aaaagatgtt aaatttacaa tttgcagaaa caatggaatt gacagaagct
     2521 gagttggaga tagtttatgg aggggaattt gggaataatg ctgttatccc agccggtgct
     2581 tggggagggt tcgggacacc ttggtcaatc actaatttct ggaagaaaaa ttttaacgat
     2641 agacctgact ttgattctga ccgccgtcgt tattaatatc caaagccctt gccttttctt
     2701 gggtaggggc tgtctttatt tcatagtata ggaggaaata gaatgaaaaa gataatctca
     2761 caccgctact ttattatagt ttttctacta gttattgctg accagaagtt cagtgttcta
     2821 gttttacgca gcgaccttgt tactgggcta tctgactttg cctattatct gtcggatatg
     2881 atgttgaatt ttcttgtggt tttatttgct cttattgcta tgatttggtc ggggaaatgg
     2941 cagaaaatca atagtagaaa gtttaaagga tcctatcttt tctattcctt cctagctctg
     3001 cttgcttttg ttgtttggaa tttcgttacc ttttttcttt tcccacctac tcgaaatgaa
     3061 atttcttatc aacatgctgc tccgactttt acaggggcta cagcattttt gatgtatttt
     3121 ttctatcctg tgattgcagg tcccattttt gaagagataa tccatcgggg attggtgatg
     3181 acagctctgg aaaaaggaaa gaaatggggg ctagatgtac ttggctctgc tattttattt
     3241 ggggtctcgc acattagtaa tcacggttgg gtcttgacag actttgtctt ctatatgggt
     3301 ggaggtctta tatttgcagt cttatttaga atgacaaagt caatttattg gcctattgga
     3361 ctgcatatag tctacaatgg tattggtcag cttttgatgt tactgtaatt ttggttgtta
     3421 gtagtatcgc ggtctattct tggggaaaga ttcccatttg aacttaagaa ggagttgtaa
     3481 tgaaagtatt tcttcaaaat agagatttta ggcaattaac tatcaaccag tggatttcaa
     3541 cgcttgggga tacgattttt tatctggcct tcctgaatta tgtggcagat gcgtcttttg
     3601 cccctttggc gattttactt atcacgattt cagaaaccct tccccaagtt ctacaaatct
     3661 ttctgggagt tttggcggat tttcaacatc atcgtgtctt gaaatacaca gtcattagtt
     3721 ttacaaaatt tttgctttac tctatagtgt ccctatcgct ttcagggcag tctttttcct
     3781 tgttgctagt aacctttatt tgtatgatta acctcttgtc tgacacattg agttattttt
     3841 caggcgccat gctcactccg attttcatta gaattattgg gcaagatcat ctggcagaag
     3901 ctattggatt taaacagtca actgttagtt tagtgaaaac aatcagtaat atcctaggag
     3961 gagtcttact aggtattcta tccatccagt ttatttcctt actgaacgct cttacctttt
     4021 taatcgcatt tttaggtatc ctcttcataa aaactgacct cttgaaagta gaaaaaacga
     4081 ttagctatca agaaggactc tctgtaaaat ccttttgcca gcatttgctc caatcatcga
     4141 aattgatatg gaatatgaat aaggtgctct tggttttgtt tattatctct actagtcaag
     4201 cagtgataaa tgttacagtt cctgtctcta ctctattttt gaggaatcaa ccctttttga
     4261 atttacaaac aggtcaatct cttgccttgc tatccacttt tgaactgtca gccctgattg
     4321 tcggaagcct tgtaagtggc tatctgcaac ataccatttc cataaaaaca actctctatg
     4381 cctcacttgt catccagttg cttcttctag taggatttgc cacagttcgt tttgactgga
     4441 ttctcatctt tagtaccttg gatgcctttt tcgcaggtgt tctctctcct agattgcaag
     4501 aactcgtctt taaacaaata cctgaggagt caatgggagc agttcaatct tctatcagtg
     4561 ccattacggt tgttttacct agcttattta caatatcttt ggtaaccatt gctactagct
     4621 ttggaactct ggcagttagc tttgttttat tgctatttct tctagttgcc tttgttatgc
     4681 ttctgaatat tcgtgaaagt atttagtgga gaatttctat aatatatgtt tgagactgga
     4741 ttgccagtct ttttatgatg gtcaaaatca acagactttt tctcttttct gaatgtgtta
     4801 tagtagactg aatctaaaat agtacgaaac aattgctaaa acatttatag aaattaattt
     4861 tactttccca atcgatttgt tctcatctta tttcaatctg ctatataata gtccatgctg
     4921 tggctggatt cttttcagcc tacttatact cttcgaaact ctcttcaaac cacgtcagct
     4981 tcaccttgcc gtatatgtgt tactgacttc gtcagttcta tccacaacct caaaacagtg
     5041 ttttgagctg acttcatcag ttctatctgc aacctcaaaa cagtgttttg agcaacctgc
     5101 ggctagtttc ctagtttgct ctttgatttt cattgagtat tattaagaca atatgaggag
     5161 aaagatgaaa gaaaaaggat tttaggaggg ggcgcaggca gccatgccaa cggctcttgg
     5221 ctatgtcagt atcggcctgg cctgtggaat tatcggtgcg ccctatgtga cacctgttga
     5281 gatgggcttg atgagtctct ttgtttatgc tgggagtgcc cagtttgcca tgttggcact
     5341 gattgtggtt caagctcctg tggcagctat tgctatgacg gtttttctaa tcaatttgcg
     5401 tctctttttg ttgagcttac acgcatcgac ttatttccgt cataccagtc tttggcacaa
     5461 tatcggtatg tctagtatct tgacagatga gacctatggc gttttgatgg gcgaattagc
     5521 ccatacagat aaggtcaatc cgatgtggat gcacgggaac aatctcaaca gctatgtggc
     5581 ttggtttgtg ggaacagtgg tcggaacggc tctaggtgac ctgttgccaa atccagaaat
     5641 ctttggttta gattttgccc tggttgggat gtttatcggg atttttgctt cgcaattcca
     5701 gatgatgcaa agacggattt ctgtccgcaa tctgctcatt atcttagcag ttgttgcagt
     5761 gtccttcttt ttacttttga cagtggtgtc tcagtcacta gctgttctgt ttgcgacgct
     5821 acttggttgt agcatgggga tggttttaga tggtcagtaa gtatctttta ttagcagtta
     5881 ttttctctgg tcttgtgacc tggattcccc gtatgattcc cttcatcttg gtcaagtata
     5941 agggcctgcc tacgattgtt gagcgttttt tgaagttttt gcctgtttcc attatctttg
     6001 ccttgattct ttcaagagta gtgacaggta aggttgggaa ccttcctcaa atcaaatgac
     6061 tggacttctt agcagtcttt ccaacagctt gggtagcttt tcgctaccgc aatctagtcg
     6121 gtacggttct ctttggagta gtcttgattg ccgtcttgcg tttggtcttt taaataagtc
     6181 ataaagaaaa cttatcacag agatagatat catataatgg cgtaattact ttttttctga
     6241 taagattata aggtattcta ttttggagga aatgacatga aaaaaatcgt taaatactca
     6301 tctcttgcag cccttgctct tgttgctgca ggtgtgcttg cggcttgctc aggtggtgct
     6361 aagaaagaag gacaagcagc tagcaagaaa gaaatcatcg ttgcaaccaa tggatcacca
     6421 aggccattta tctatgaaga aaatggcgaa ttgactggtt acgagattga agtcgttcgc
     6481 gctatcttta aagattctga caaatatgat gtcaagtttg aaaagacaga atggtcaggt
     6541 gtctttgctg gtcttgacgc tgaccgttac aatatggctg tcaacaatct tagctacact
     6601 aaagaacgtg cggagaaata cctctatgcc gcaccaattg cccaaaatcc taatgtcctt
     6661 gtcgtgaaga aagatgactc tagtatcaag tctctcgatg atatcggtgg aaaatcgacg
     6721 gaagtcgttc aagccactac atcagctaag cagttagaag catacaacgc tgaacacacg
     6781 gacaacccaa ctatccttaa ctatactaag gcagatttcc aacaaatcat ggtacgtttg
     6841 agcgatggac aatttgacta taagattttt gataaaatcg gtgttgaaac agtgatcaag
     6901 aaccaaggtt tggacaactt gaaagttatc gaacttccaa gcgaccaaca accgtacgtt
     6961 tacccacttc ttgctcaggg tcaagatgag ttgaaatcgt ttgtagacaa acgcatcaaa
     7021 gaactttata aagatggaac tcttgaaaaa ttgtctaaac aattcttcgg agacacttat
     7081 ctaccggcag aagctgatat taaataattt cttgaaatca tccattctga gtaagatggg
     7141 tggtttctca gtttttaggg atatagtttt aaactatata tctgactatc taataacaat
     7201 ttgtgaaatc aaacaaattg tgagatacta gtacggtatt atttttaagg agaaagaatc
     7261 atgaaaatca aaaaatggct tggtctagca gcccttgcta cagtcgcagg tttggctctt
     7321 gcagcttgcg gaaactcaga aaagaaagca gacaatgcaa caactatcaa aatcgcaact
     7381 gttaaccgta gcggttctga agaaaaacgt tgggacaaaa tccaagaatt ggttaaaaaa
     7441 gacggaatta ccttggaatt tacagagttc acagactact cacaaccaaa caaagcaact
     7501 gctgatggcg aagtagattt gaacgctttc caacactata acttcttgaa taactggaac
     7561 aaagaaaacg gaaaagatct tgtagcgatt gcagatactt acatctctcc aatccgcctt
     7621 tactcaggtt tgaatggaag tgccaacaag tacactaaag tagaagacat cccagcaaac
     7681 ggagaaatcg ctgtaccaaa tgacgctaca aacgaaagcc gtgcgcttta cttgcttcaa
     7741 tcagctggct tgattaaatt ggatgtttct ggaactgctc ttgcaacagt tgccaacatc
     7801 aaagaaaatc caaagaactt gaaaatcact gaattggacg ctagccaaac agctcgttca
     7861 ttgtcatcag ttgacgctgc cgttgtaaac aataccttcg ttacagaagc aaaattggac
     7921 tacaagaaag cacttttcaa agaacaagct gatgaaaact caaaacaatg gtacaacatc
     7981 attgttgcga aaaaagattg ggaaacatca cctaaggctg atgctatcaa gaaagtaatc
     8041 gcagcttacc acacagatga cgtgaaaaaa gttatcgaag aatcatcaga tggtttggat
     8101 caaccagttt ggtaataaga aacagggagg tgggagagaa aattccacct cttgcttttg
     8161 tatagagtat agattgtaaa gaagactatt cgttcataga aaggtagaga gaatatggtt
     8221 tttcctagcg aacaagaaca gattgaaaaa tttgaaaagg atcatgtagt ccaacattat
     8281 tttgaggttt tgcgtacctt gatttctaag aaatcagtct ttgcccagca ggttggactc
     8341 aaggaagtcg caaattatct gggtgagatt ttcaagcgtg ttggagctga agtggagatt
     8401 gatgagagct atacagcgcc ctttgtcatg gcacatttca agagttcgcg tccagatgcc
     8461 aagaccttga ttttctataa ccactatgac actgtgccag cggatgggga tcaggtctgg
     8521 acagaggatc cttttacgct ttcggtccgc aatggcttca tgtatgggcg tggggttgat
     8581 gacgacaagg gtcatatcac agctcgcttg agtgctttga gaaaatatat gcagcaccat
     8641 gatgatttac ctgtcaatat cagctttatc atggagggag cggaggaatc ggcttcaaca
     8701 gacctagata agtatttgga aaagcatgca gacaaactcc gtggggcgga tttgttggtc
     8761 tgggaacaag ggaccaaaaa tgccttggag cagctggaaa tttctggtgg caataagggg
     8821 attgtgacct ttgatgccaa ggtaaaaagc gctgatgtgg atatccactc gagttatggt
     8881 ggtgttgtgg aatcagctcc ttggtatctc ctccaagcct tacagtctct tcgtgctgcg
     8941 gatggccgta tcttggttga aggcttgtac gaagaagtac aagagcccaa tgaacgagaa
     9001 atggccttgc tagaaactta tggtcaacga aacccagagg aagttagtcg gatttatgga
     9061 ttggagttgc ctctcttaca ggaggagcgg atggcctttc taaaacgttt ctttttcgag
     9121 ccagcgctta atatcgaagg aatccagtct ggttatcaag gtcagggtgt taagactatt
     9181 ttacctgcag aagccagtgc caagctagag gttcgtctgg ttccgggcct agaaccgcat
     9241 gatgttctgg aaaaaattcg gaaacagcta gacaaaaatg gctttgataa ggtagaatta
     9301 tactatacct tgggagagat gagctatcga agcgatatga gcgcaccagc cattctcaat
     9361 gtgatcgagt tggccaagaa attctatcca cagggcgttt cagtcttgcc gacgacagcg
     9421 gggacaggac ctatgcatac ggtctttgat gccctagagg taccaatggt tgcattcggt
     9481 ctaggaaatg ccaatagccg agaccacggt ggagatgaaa atgtgcgaat cgctgattat
     9541 cacacccata tcgaattagt agaggagctg attagaagct atgagtagag atattatcaa
     9601 gttagatcag atcgatgtga cttttcacca aaagaagaga accattacag cggttaagga
     9661 tgtgaccatt cacatccaag aaggggatat ctacggaatc gttggatatt ctggagcagg
     9721 aaaatcaacc cttgtacggg tgattaatct cttgcaaaaa ccatctgcag ggaaaattac
     9781 cattgacgac gatgtgattt ttgacggcaa ggtgaccttg acggcagagc agttgcgtcg
     9841 taaacgtcaa gatatcggaa tgattttcca gcattttaac ctgatgagcc aaaagacagc
     9901 agaggagaat gtagcctttg cccttaaaca ctctgaactc agcaaggaag aaaagaaggc
     9961 taaagtagct aagttgttgg acttggttgg tttggcagat cgtgctgaaa actacccttc
    10021 acaactatct ggagggcaaa aacagcgtgt ggcaattgcg cgtgccttgg ccaatgatcc
    10081 aaaaatcttg atttcagacg agtcaacttc tgcccttgat ccgaagacaa ccaagcagat
    10141 tttggccttg ttgcaagatt tgaaccaaaa attaggcttg actgttgtct tgattacgca
    10201 tgaaatgcag attgtcaaag acattgccaa ccgtgtggcg gttatgcagg atgggcattt
    10261 gattgaagag ggtagtgtgc ttgaaatctt ctcagaccct aaacaacctt tgactcaaga
    10321 ctttatctca acagctacag gtattgacga agccatggtc aaaatcgaga agcaagaaat
    10381 cgtggaacac ttgtctgaaa acagtctctt ggtgcaactc aagtacgctg gatcttcaac
    10441 agacgagcca cttttgaatg aattgtacaa gcattatcaa gtaatggcta atattctcta
    10501 tgggaatatc gaaatcctcg atggtactcc tgttggagaa ttggtggtgg tcttgtcagg
    10561 tgaaaaagca gcgttggcag gtgcccaaga agccattcgt caagcaggcg tacagttaaa
    10621 agtattgaag ggaggacagt aagatggaat cattgattca aacctatttg ccaaatgtct
    10681 ataagatggg ttggtctggt caggcaggct ggggaacagc tatctaccta accctctata
    10741 tgacagttct ttccttcatt atcggaggct tcttggggct agtggcaggt ctctttctcg
    10801 tcttgacagc gccaggtggt gtcttggaga ataaagtcgt attctggatt ttagacaaaa
    10861 ttacctcaat ttttcgtgcg attcccttta tcatcctctt ggcaatcttg tcaccacttt
    10921 ctcacttgat tgttaaaaca agtatcgggc caaatgcagc ccttgtccca ctttcttttg
    10981 cagtctttgc cttctttgcc cgtcaggtgc aggttgtctt ggctgaattg gatggcggtg
    11041 tcattgaggc ggctcaagcg agcggagcga ctttctggga catcgtgggt gtttacctat
    11101 cagaaggtct tccagatttg atccgtgtga cgactgtgac cttgatttcc cttgttgggg
    11161 aaacagctat ggccggtgcg gttggagctg gtggtatcgg taacgtagcc atcgcttatg
    11221 gatttaaccg ctacaatcac gatgtgacca tcttggcaac cattattatc attttgatta
    11281 tctttgcaat ccaattcttg ggagatttct tgactaagaa attgagtcat aaataaaaag
    11341 agccgcgtgg ctctttttaa ctgatcagat tttctgtgca aattttttac tcaaggcttg
    11401 tccaatcaag gcacccacta gggctccgat gacaatactt gcgataaata gaaggacagt
    11461 tccagggttt ggagcgacca tgatacggtc gatatattct tgggattttc ctcttgccag
    11521 aagagtagcc atataggctt tgggcgcaat ccacataagc aagattggtc ctgttgtact
    11581 aaaggcgaaa ataatgaaag aaaggaagtt ctttgttttg tccttgtatt ttcctaaatg
    11641 agctacttca tctgctagga ggccacagat aattccagga aggaaggaac cagcaccgtg
    11701 tttagttccc aagaaaaaga gggcaatgac aaggccgata gtggtaatgg ctccaaagcg
    11761 cggaactttt gcgactagga tcatatagac gctaccgccg acaagggcag taaaggcagg
    11821 cgcataaaac atgtttccag tttggtcaaa gagattgccc aaaaggacac caatccccat
    11881 gcagaggaag taaagaactg caaaaagcag tgtagttaag atagatttct tcatgaattg
    11941 tctcctgata attttttcac aattctcatt gtaccacggt ttggtgggat tgtaaatgga
    12001 tactagaagt ttttgaaaac gcttgaaata tgatataatg gtttcatagt tatttttagg
    12061 ggaatatcat gggtagattt ttagactttg tctttaatcg tttcttttta gggatgattg
    12121 cgacagcctt cttttggcta ttaactttag caggagggat tatccttggt ctagcgccgg
    12181 ctagtgccac cttgatgagc ttatatgcag aacatggtta tagctttcgg gaatacagtt
    12241 tgaaggaggc ttggtctctt tacaagcaaa attttgtctc aagcaacctg attttctata
    12301 gctttttagg tgtgggtcta gttttgacct atggtttgta tctcttggtg caattgcctc
    12361 atcagaccat tgttcatttg attgcgaccc ttttgaatgt cctagtagtt gccctgatct
    12421 ttttggctta tacagtatct ttaaaattac aagtttattt tgccttgtcc tatcgaaata
    12481 gtctcaaatt atccttgatt ggcatcttta tgagtctagc agctgtggcc aagattctcc
    12541 ttgggactgt gctacttgta gcaattggtt actatatgcc tgccctgcta ttttttgtag
    12601 gaattgggat gtggcatttc tttatcagtg atatgttgga acctgtctat gaaatcatcc
    12661 atgaaaaatt ggcgacaaaa tagaatgaag cagttttggc tacatacgct tctaagaacc
    12721 tatagttcag tgatgatcat tatcattgcg agttttgcaa tcttactctc ttacgctgac
    12781 tgggattcac gtgaaaagga agcccagaga gtagcccagc gtgtaactgc tagaacagtg
    12841 agtgaaattg aatattacca tagagagtca acccagatag ctcaggcttt agttgaaaac
    12901 caagctcgta ttgagggaat ctataaatac tttagtctta gcatgccaga ctatttttac
    12961 tggcaattag agcggaaagc ttcgccttat atatcagtct ctctgtatga aaatgttgat
    13021 gacctctatg ttcgaaatga ttttgtaact ggagtggcca ttgcttttca agattacaag
    13081 gaagtctatg tttctactaa agacaaacgt agtggagaaa aaatcagggc tgaggatttc
    13141 aaaccagcag gaaatagttt tgccattccg gtgtcagatc cagtgtcaga tcaagattta
    13201 ggagtgattt acatctcctt ggatcctgct gttttatacc atgccattga taatactaga
    13261 ggtcatactc cgatggcagt aacagtgacc tcaccttttg atacggagat ttttcatatt
    13321 ggtgagacag ttgataagga gagtgaaaat tggctagttg gcttaacttc tcatggatat
    13381 caggttcagg tggcagttcc taaaaacttt gttttacaag gaacagtgac tagctctgct
    13441 ttgattgtgg gtttgagcct tctctttatt gtcattcttt atctgacttt gaggcagact
    13501 tttgctaatt accaaaagca ggtagtggat ttagtagaat ccattcaagt cattgctcaa
    13561 ggcgaagagg ggcgtcggat tgacatttcc gagaaagatc aggaattact cctaatcgcg
    13621 gagacgacca atgatatgtt ggatcgattg gaaaagaata tccatgatat ttaccagtta
    13681 gagcttagtc aaaaagatgc caatatgcga gccttgcagg cgcaaatcaa tcctcatttt
    13741 atgtataata cgctggagtt cttgcgcatg tatgcagtta tgcagagtca agatgagttg
    13801 gcagatatca tttatgaatt cagtagtctc ttgcgtaaca atatttccga cgaaagagag
    13861 accctcctca aacaggaatt agaattttgc cgtaaataca gctatctctg catggttcgc
    13921 tatcccaagt ccattgccta tggtttcaag atagatccag agttagagaa tatgaagatt
    13981 cccaagttta ccttgcaacc gctggtagaa aactatttcg cgcatggtgt tgaccacagg
    14041 cggacagata atgtgattag catcaaggct cttaaacagg atggttttgt ggaaattttg
    14101 gtggtcgata atggtagagg aatgtcggct gaaaagttgg caaatatccg agaaaaatta
    14161 agtcagagat attttgaaca ccaagccagc tacagtgatc aaaggcagtc tatcgggatt
    14221 gtcaatgtac acgagcgttt tgtgctctat tttggagacc gctatgccat tacgatagag
    14281 tctgcagagc aagccggtgt tcagtatcgt attacaattc aagatgagta gaaagggaga
    14341 aaatgtataa agtattatta gtagatgatg agtacatggt gacagaaggt ctgaagcgtt
    14401 tgattccctt tgataagtgg gatatggagg tcgtcgcaac agccagtcat gccgatgaag
    14461 ctctagaata tgttcaggaa aatcctgtcg atgtcatcat ttccgatgtc aatatgccag
    14521 acaaaacagg gcttgatatg attcgggaga tgaaagagat cttaccagat gctgcctata
    14581 tcctgctctc aggttatcag gagtttgatt atgtaaaaag agcaatgaac cttagtgtgg
    14641 tggactattt ggtcaagcct gttgataagg tagagctggg aaatctgctg gagaagattg
    14701 caggtcagct cggcgagaga gggaagaaaa gtcagactct tagtcaagaa ttagacgagg
    14761 ctggatttgt tagttattta ggggataagg agaattggtg gataggtcta tccaaggaaa
    14821 aacaaggttc cttcgccatt ccctactatg tcttgggcca agactggcag attttcattt
    14881 ctgaccaacc cctagatggt ttagtcgtta caccttttga agctccttat caagaacact
    14941 ttgaacgctg gaagctgaat gctgagaaaa ccctctttta cggttctgta aatctgcagc
    15001 agtctgagag tctctttgcc tattacgaac cgatttatag ggttatcatt cagggaaatc
    15061 tcaatcaaat cgtagaagag ttaaatctct tggagaaggt agttcttgaa aatacgccgc
    15121 gtgttccgat tactaaacag ctttttattc agtttgtcat ggatgttttc catttatttg
    15181 aacatctcaa agctgatgac ctgacagaca tcgtcaaaac cattcatgct attcaatcct
    15241 tcgatgaatt ggttccttat atcaaggaaa ctctgaccag ctttttcggt caataccgta
    15301 tgaatgaaaa tgtggtcagt gtgctggaag tcattggtcg tgattaccaa aaagagcttt
    15361 ccctcaagga tatcagtaag gctctcttta tcaatcctgt ctatctaggg cagttgatta
    15421 agcgtgaaac cgattcgact tttgcagagt tactaaacaa acaacgtatt aaggctgccc
    15481 aacaactttt gctttcaact agtgacagca tcgaagatat ttgttatgct gttggttaca
    15541 gtaaccttgg atatttctat aaagtttttc gaaaattgtg cggaaaatcg ccaaaagcct
    15601 accgaaaaca ggtagaaact atactataag atttgtattc ctttacaaaa ggtgctataa
    15661 tattatcagg aggttctatc atgaaaaaga aaccaattta tctatgggtc ttgctaatct
    15721 tgtctgccct tatttcagtt ccgtctctgt ttggaattgt gagtcccttg cctagtaaag
    15781 aagcccttcg tgctgctcag aaacaagttg caggggtcaa tgctcagcaa ttagaagacc
    15841 agcttaatta tacctataga gtagcagaag catctcattc tatttttaat gttgctttga
    15901 ttgtgctatc tactatttta gtggtcgtag cgattgtctt ccttgttcgt aaaaatttgc
    15961 aatatgcaaa ctatacttac gttggttatg ttttgttagc tattattggt tcgatttatg
    16021 gctatgttgg tttacaagac gctgtgcagt tggttcaaga tgagagcatg cgtttgacag
    16081 tgagtattgg ttcaaaagct gttagcattt tctatatcgt catcaatgtt ctcttcctag
    16141 cccttgtctt ctataagatg tggcgacaac agaaagcctt ggcagaagaa gaggaaacag
    16201 aagagcttac ctaagtattg acaaaaaaga actatcaaga tacaatcttg gtagttgttt
    16261 tttgattata gataaaatca tggaggtaca tatgaagaca atttctttag tttatattag
    16321 tttgagtggc aacactgaaa gttttgtgac gcgcttgaaa gactatctct tgtcccagta
    16381 caaagggatt gaggttcaaa agattcatat caaggattta gtcaaggaag gcaaaaattt
    16441 ctatgaaatg gaccatccct atgtcgcttt tttgccgacc tatctcgaag gtgggaatgg
    16501 cgtggataac ggagatgttg agattttgac gacaccggtg ggagatttta ttgcctatgg
    16561 taacaatgct agtaagtgtt ttggtgtggt tgggtcagga aatcgtaact ttaataacca
    16621 atactgccta acagccaagc aatacagtca acgctttggc ttccctgtat tggctgactt
    16681 tgaaatgcga ggcatgctgg aagatatcaa acatgtcgca gctattatcg cagatttgta
    16741 tgagttggaa aaggagaatt aatactcaat gaaaatcaaa gagcaaacta ggaagctagt
    16801 cgcaggttac tcaaagcaca gctttgaggt tgcagataga gctgacgtgg tttgaagaga
    16861 ttctcgaata gtataaagtt cttataagag gtggttgaag ttgttcaact gttttttgag
    16921 tataaacagt ctttaagaac gtaaaaaagc ataagttcag gtcttcaaaa ccttgttctt
    16981 atgcttttta tcatagaaat atttgctgaa ttttctcttg aaatgaaacc ttatcttcat
    17041 ctcgcgcttg tcccttaccc tgcttttccg attgcgagtg cgtagataaa gaagatggcg
    17101 aagccaaaga ggaaaatcaa tcccgcaatg gcaaggtgtt tgagccaaga aggaagattt
    17161 ttgttttcac gcgttaccaa ggcgtaattc aaaagagcaa agaaaggtgt tgtcaggaaa
    17221 gagccaatca tggcaaagcg gagcatggtt gaaacctgac cagcgaagaa cttgataatg
    17281 acgataccga tgatagcagt gatggtcatc cagatgttca aagatttacg attgtcctct
    17341 ttttgactga ttagcagtcg gagagattcc tgattaacgc gagaatagcc atcgataaca
    17401 gttataactg ttccaaagat acagaggaag gcaataaagg taatcaagta acgggaccat
    17461 tcgccaagaa cagaggcata catacccacg aattgagaga tgtatttggc tgaagcagct
    17521 tcaaccgcct gccctgtagg atactgaatc agtgctccca gtgccacaaa gaagacggct
    17581 aggatagctg ttccaatata accagtgtta aagtcaaaca gagcgtcttc tgtgttaaag
    17641 ttgacggtct ttctcttttc agctgaccaa agtgaattga tagctgaaat ttcaatagga
    17701 gccggcatcc atcctaggag ggagacgatg aagggcagag ctgccatttg ccaaggtgtc
    17761 ttctcgacaa aatcagaact gtattctgga tgcttgaccg ccgcaatgat aactgcaaga
    17821 acagtcgcaa tggttaaggc agacataatc catttgacca tgccgtctaa aagtttgtag
    17881 cctccaaaga gtagcatagc ccaaatgatt gcaacgagaa tgagggacca ctgagtaatg
    17941 ctaagtccaa tcattgggaa ggcactggcg atgatagctg agcacagaat ggcaacacca
    18001 gccgtgttga ccatagccga aaagacattg aggataaaga aaatccagag atagagtttt
    18061 cctttttcgg cataaccttc aaccaaagtc tttccagtat cagctgtgta ttcagcacca
    18121 aaacggaaaa atggatattt aaagacattg gctaagatga ccaagagaag tagagaccaa
    18181 ccgtaagaac cgccagcttg agttgaggat acaatgtggg aacctccaac agcggcagtt
    18241 gccattagga ttccaggtcc cattgctttt agcttgcttg cccaggttga ttgatttaag
    18301 gaaatagctt gcgacatgat aaatactcct ttttgaattt tcagaataat ctgtatatgt
    18361 aatctatatt ctacaaaaaa ttttggaaaa atgcaagagt attttgaaaa aagatagaaa
    18421 atttacaaag aagatctgaa cccaaatttc aagttgaagt tagccaccca aaagaaattc
    18481 acttggcgac ttgtagtcca agcatttttt agggtagttg ttaatccaat tttcgataaa
    18541 agctacttct ttcggagtcg ttttcttggt tcctttaggt aaccatctcc gaattaatcg
    18601 attatgattt tcatttgaac ctctctccca tgaagagtaa gcatgtgcgt agtagatatg
    18661 ttcctcagga aatacctcag acaatcgttt gaactccgaa ccattatctg cagtaatgga
    18721 cagaatacga tgctccccta atagtaacgt aagcgcctga ttgacagatt cagcagtttt
    18781 atttggaatt aaccttataa tttggtgtct gctccgccgg tcggttaaga ctaacaggca
    18841 ataatttttt atcttagtca gtaggacggt atcaatttca taatgaccat tttccaagcg
    18901 aagattaata acgtcaggac gttcttcgat agatttacct gccggcttaa agttcggact
    18961 agcttgcttc ttgacacctt tcctttttct gggataaagc atgtcggcct tcgtcaatcc
    19021 taaatgacca ttatgaaacc agtagtagat ggttgaaata ccaactttca cttgcttctt
    19081 gttaaccatc atttcaggcg aaaatttttg cttatgatag tgtaagatct tctctctgat
    19141 ttcctttgtt aaaattaact ttttcaccga ccgttttcga ttgaattggt aaacagtttg
    19201 tgcgtaatcg gcagaataga cctttttgta tagccctttt ctcacttgtt gtaaagttgt
    19261 acctcttttg acttcagtat gaatcgtttg aggcgccttt cctaacaagc ctgcaatttc
    19321 acgattggac ttattttcat tcttccaccg ctcaatcaag cgacggttat ctattgtcaa
    19381 atgtttccct tttggggtat aatgttcttg catctctgtg cctttccttg tgtttgtggt
    19441 gaacaacaag tatagcacag aggtgttttc ttatacctta aatcacattt catttgacaa
    19501 caggaaccct tgaacctgtt ttttcagcta aaccaaggct atgattagcc ttggccacct
    19561 agcctaacag tttcaaacct gttatcaaat gaaatcatca acttactcaa acatagtgaa
    19621 acatctaatt cttgactaag gtaaggtggc taacttcatt atagaacttt caaaagaaga
    19681 tctgaaataa ctgttatgat atagaggatt gaaactagaa tagtacacct ctgcttctaa
    19741 aacattgtta gaaatcgatt tgactgtcct gatcgattta tcctgttctt atttcatttc
    19801 actatagtaa ggtgcagcag gataaagaaa aaccgagaag tttctttctc ggatttgctt
    19861 attatgaggt tcctattttc tatgctccaa gagttgattg atgtgatcta cttttttagc
    19921 ctctctttta tagagaatag cccagatgat gagatagaca atcgcaaact cgataatgag
    19981 ctggaggtag aaaatccagt ggaaagggaa ccaaccagca agagttgcta gtgggacaaa
    20041 gccagccagc ataaggaaga aatgagtcag agtggcacga agcatgctcc agtcacggct
    20101 aaataagcgg ttgccaaagt tgaagagcat accgatggtt gcccagataa gtgtgcagta
    20161 gagcaagacc agggcaccgt gaacctgatg ctgatccatc acttggccta tgagagagta
    20221 gggatttagt ggtgcgtagg tatttggtgc ataaatgagt gaaaagagga tagagaggat
    20281 gaggccgata agaacaccgg tagctgcatc gtgaaatact tgttttttca tagttctaat
    20341 ttctccttga tggtttttag ataacggcgt gaagagtagg tgaagctttc gtttttcaag
    20401 aaaatttcta ccagaccgtt tggcgtgagc ttgaggtgag agatggaatc gatattgatg
    20461 atttctgatt gggaaatttg gataaaattg cttggcaaga gtttaagaac ctgatagagt
    20521 cgcaaatcaa tgctgtaggt ctgactcgcg gtttctgcta gaaccttccg attctcgata
    20581 tagaagcgct gaatcttgcc aatctcaact agatagacct gatcatcgat ttttcctttg
    20641 attttttctc tttggtccag attttctgcg aactcgatga ctttctggac tttttcggtt
    20701 tcttgaggtg cttggacaat cagcttttcc tcctcgtaag tctcactaat ctgtagttct
    20761 actttcataa atttctctcc ttgtttttca tacaaaatta atctcacttc ttgtacacct
    20821 ttattaatac tcttcaaaaa tctcttcaaa ccacgtcagc gtcgtcttgc cgtaggatag
    20881 ttgttgactt tgtcagtttt atctacaacc tcaaaacagt gttttgagct gtctgcgtct
    20941 agctttctag tttgctcttt gatttttatt gagtatacca ctattttact ccctctggca
    21001 agggactttg tctatgtgga gggattgggc tcctatgtgg tggagttttt ctgttctttc
    21061 tgaaatatgg tataatagca ctaattaatt tctaggaaaa tagatacaga aaggggctga
    21121 aagatgtctc atattattga attgccagag atgctggcaa accaaatcgc agctggggag
    21181 gtcattgaac gtcctgccag tgtggttaaa gagttggtag aaaatgccat tgacgcgggc
    21241 tctagtcaga ttatcattga gattgaggaa gctggtctca agaaggttca aatcacggat
    21301 aacggtcatg gaattgccca cgatgaggtg gagttggccc tgcgtcgcca tgcgaccagt
    21361 aagataaaaa atcaagcaga tctctttcgg attcggacgc ttggttttcg tggtgaagcc
    21421 ttgccttcta ttgcgtctgt tagtgtcttg actctgttaa cggcggtgga tggtgctagt
    21481 catggaacca agttagtcgc gcgtgggggt gaagttgagg aagtcatccc agcgactagt
    21541 cctgtgggaa ccaaggtttg tgtggaggat ctctttttca acacgcctgc ccgtctcaag
    21601 tatatgaaga gccagcaagc ggagttgtct catatcattg atattgtcaa ccgtctgggc
    21661 ttggcccatc ctgagatttc ttttagcttg attagtgatg gcaaggaaat gacgcggaca
    21721 gcagggactg gtcaattgcg ccaagcaatc gcagggattt acggtttggt cagtgccaag
    21781 aagatgattg aaattgagaa ctctgaccta gatttcgaaa tttcaggttt tgtgtcttta
    21841 cctgagttga ctcgggctaa ccgcaattat atcagcctct tcatcaatgg ccgttatatc
    21901 aagaacttcc tgctcaatcg tgctattttg gatggtttcg gaagcaagct tatggttgga
    21961 cgttttccac tggctgtcat tcacatccat atcgaccctt atctagcgga tgtcaatgtg
    22021 catccaacta agcaagaggt gcggatttcc aaggaaaaag aactgatgac cctggtttca
    22081 gaagctattg caaatagtct caaggaacaa accttgattc cagatgcctt ggaaaatctt
    22141 gccaaatcga ccgtgcgcaa tcgtgagaag gtggagcaaa ctattctccc actcaaagaa
    22201 aatacgctct actatgagaa aactgagccg tcaagaccta gtcaaactga agtagctgat
    22261 tatcaggtag aattgactga tgaagggcag gatttgaccc tgtttgccaa ggaaaccttg
    22321 gaccgattga ccaagccagc aaaactgcat tttgcagaga gaaagcctgc taactacgac
    22381 cagctagacc atccagagtt agatcttgct agcatcgata aggcttatga caaactggag
    22441 cgagaagaag catccagctt cccagagttg gagtttttcg gacaaatgca cgggacttat
    22501 ctctttgccc aagggcgaga tggactttac atcatagatc agcacgctgc tcaggaacgg
    22561 gtcaagtacg aggagtaccg tgaaagcatt ggcaatgttg accagagtca gcagcaactc
    22621 ctagtgccct atatctttga atttcctgcg gatgatgccc tgcgtctcaa ggaaagaatg
    22681 cctctcttag aggaagtggg cgtctttcta gcagagtacg gagaaaatca atttattcta
    22741 cgtgaacatc ctatttggat ggcagaagaa gagattgaat caggcatcta tgagatgtgc
    22801 gacatgctcc ttttgaccaa ggaagtttct atcaagaaat accgagcaga gctggctatc
    22861 atgatgtctt gcaagcgatc tatcaaggcc aatcatcgta ttgatgatca ttcagctaga
    22921 caactcctct atcagctttc tcaatgtgac aatccctata actgtcctca cggacgtcct
    22981 gttttggtgc attttaccaa gtcggatatg gaaaagatgt tccgacgtat tcaggaaaat
    23041 cacaccagtc tccgtgagtt ggggaaatat taaaagtata aaaaagtctg ggaaaaattt
    23101 tcaaaatcag aaaaacgcat aaaatcaggt gttcaaaaac cttgatttta tgcgttttat
    23161 catggaaata gttacttcat gttttcctaa ttcttttcga aactcttttt aaaccacgtc
    23221 agttttatca gtaatctcaa aacagtgttt tgagctaatt ttgccagttt tgtctgtaac
    23281 atcgaagttg tgttttacca ctctgcgact ggtttcctag tttgctctat gattttcaca
    23341 gagtattaaa ttgcgatttt gccaagtttc tttattcgtc taaaagtaga gtctgttcta
    23401 tgcgtctaat gtacgaatta ggttgaccat ttcaatagct ccttgtgcac actcagaacc
    23461 cttatttcct gctttggtac cagctcgttc tatggcttgt tcaattgtat ctgtcgttag
    23521 cacaccaaac ataacaggaa tttcgctatt taaactgatt tgggcgattc ccttagatac
    23581 ctcgctacat acataatcat aatgacttgt attccctcta atgacagctc ccaagcagat
    23641 aattgcatca tattttttac tttttgccat ttttgatgca atcagtggta tttcaaaagc
    23701 tcctggaacc caggctacct ctatatcttt ctcgtttaca ttctctcttt tgagattatc
    23761 tagtgctcca gataataatt ttgaagttat aaattcatta aatctcgcta caacaatacc
    23821 tattttaata ttgtttgcta ctaaattacc ttcataagtg ttcatttatt tttcctccat
    23881 atttaaaatg tgacccattc gatttttctt tgtttctaaa taaaaactat cgtaaggatt
    23941 ggcttctatt tcgattgata ttctactgga aatggtaatt ccatattttt ctaactgttc
    24001 aaccttgtca ggattatttg tcagtaaatg aagtgactga agtcccagat ctttaagcat
    24061 ttgtgctcca atatgatatt ctcttaaatc accttcaaag cctaatgcaa gattggcatc
    24121 aagcgtatcc atgccttgat cttgtaaatg ataggctttt aatttattga taagtccaat
    24181 tcctcgtccc tcctgtcgca agtaaagtaa gacacccgaa ccattctcaa caatcatttt
    24241 catagcttta tcgaattgct gtccacaatc gcaacgtaaa gagcctaaaa catctcctgt
    24301 taaacattcg gagtggaccc gacataatac attggcttca tcctctatgt ttcccataat
    24361 aagagcaaga tgatgttccc catttagttt atctatatag ctaattgctt tgaaattacc
    24421 gtatctagta ggcatattga cagttgaaac tcgttctatc agctgatcat atacttttct
    24481 atattcttgt aattctttga tggtaattag tggaatgttg tgtttcttcg agaactgaat
    24541 taaatcatct gttctcatca ttttgccatc atgattcatt atttcacaac ataggccaca
    24601 ctcttttagt ccagctaatt ttaataaatc aacagttgct tctgtgtgtc catttctttc
    24661 tagaacacca cctttttttg caattaaagg aaacatgtgt cctggcctgc gaaaatcaga
    24721 gggtgttata tcttcagcta cacacatacg tgcggtcagt cctctttcct cggcagaaat
    24781 acctgtggtc gtttctttat aatcaattga aactgtaaaa gcagtcttat gattatctgt
    24841 attgttttca accataggtg aaagcattaa ttgattagct aaactttcgc tcataggcat
    24901 acaaattaat cctttggcat aagtagccat aaaattaaca ttttctgttg tagctgcttg
    24961 tgcagaacaa attaagtctc cttcattttc tctatccttg tcgtctataa caagaacaag
    25021 tcgtcccttc tgcaatgctt ctaatgtttc ttgtattttt cgatattcca ttgactgatt
    25081 atcctttctg ctaaaatcca ttttgatata atagttcctt agatatttct gattttggag
    25141 agttatccat cagtttttgc acatatttac ctaagatatc attttcaaga tttactgtac
    25201 tcccgacttg tttactttta agaatggttt gtttcaaggt atgagggata acagatactg
    25261 aaaagtttac tttggagact ttagcgacag tcagactaat gccgtcaatt gtaatagatc
    25321 ctttttcaac tattaaatct aaaatttctt tttgtgtgtt gatttgatac catacagcat
    25381 tatcatcttt ttttattgac gagatttttc ctgtaccatc aatgtgtcct gtaacgacgt
    25441 gacccccaag tcgaccgttg atagataagg ctctttctag attcacctca cttccatgtt
    25501 ttaatagagt aagagctgtt cgactccatg tttcattcat tacatcaact gtaaaggatt
    25561 gatgattgaa atgagtaact gtaagacaga taccatttac tgctatacta tcgcctaaat
    25621 ggatatccgt taatattttt gaggctttaa ttgatagttt acaattacga gagtctttct
    25681 gtattctttc aacttttccg atttcttcaa ttattcctgt gaacatggat aaatcacttc
    25741 actttctatg agatagtcat ttcctatttg agaaaaagca taaggtttca atctaatagc
    25801 gtcatttggc aaagaaatgc cttcacctcc gacaggaaac ttggcactgc ctccaaaaat
    25861 ttttggtgca atatatattt tcagctcatc aacaatttgt tgttccaaag cactccaatt
    25921 cattagactg cccccttcta gaactaggct atcaatctgc atgtttccta gatgttgcat
    25981 taaactcgat aagtctatat gattgccttt tttctttatg gaaagtattt cacagccatg
    26041 attttgatat agcttcattt tatttttgtc ttcagaggaa gtggcaatgt aagttttaat
    26101 atcatttgct gtttttacga ttttagaggt aagaggagtt cgtaaatgtg tatcgcatat
    26161 gatacggata ggatttttcc cttcctccaa tctacatgtc agcaaaggat cgtcttgaat
    26221 aacagtattg actcccacca taattgcact aacatggtgt cgtaactgat gcacatgctt
    26281 tcttgcttct tcttcagtaa tccatttgga ttgatttgtt ttagtggcta tttttccatc
    26341 cattgacatt gcatatttca taaaaacata gggtacatgc tgggtaatat actttctaaa
    26401 actttttatt aagttaagac actcattttc taaaattcca acagtaactt gaagattatt
    26461 ttcctcaagt atctttactc cttttccaga tacaatagga ttacagtcta ggcttccaat
    26521 gactactctt gtaataccac tatcgattat agcatctata cagggaggtg ttttcccgaa
    26581 gtgacaacag ggttcaagtg ttacataaag cgtcgctccg acaggggatt ctctacagtt
    26641 tttaagagca tttctctcag catgtgggcc accaaaaaac tcatgataac cttgtccgat
    26701 gatgtgatta tcttttacaa taactgcgcc gaccatagga ttgggattga cgtaaccagc
    26761 ccctttttgt gccagtttta ttgctaattt catatatttt gaatcgctca tctcactacc
    26821 tccaaaaaaa atataccttg aataggggac tactcaaggc atacaaaaga aaacttatgc
    26881 gattaacaaa aatactctga aatgacaagt aatcatttca gagcacgcaa aaagcacaaa
    26941 tatactttta tcttctttca tccagactat actgtcggct ttggaatttc accaaatcat
    27001 gcctttcggc tcgtgggcta taccaccggt agggaattac accctgccct gaagatagtt
    27061 attcaattac agatgattat agtacttaat tttgaatatg tcaacagata aataccgatt
    27121 gtttttgata tactgtattt gtgataatcg attctcgctc ctcggataaa gaaaatatga
    27181 tatactagat aaacgaaata agagagaagg aatactatgt acgcatattt aaaaggaatc
    27241 attaccaaaa ttactgccaa atacattgtt cttgaaacca atggtattgg ttatatcctg
    27301 catgtggcca atccttatgc ctattcaggt caggttaatc aggaggatca gatttatgtg
    27361 catcaggttg tgcgtgagga cgcccatttg ctttatggat ttcgctcaga ggatgagaaa
    27421 aagctctttc ttagtctgat ttcggtctct gggattggtc ctgtatcagc tcttgctatt
    27481 atcgctgctg atgacaatgc tggcttggtt caagccattg aaaccaagaa catcacctac
    27541 ttgaccaagt tccctaaaat tggcaagaaa acagcccagc agatggtgct ggacttggaa
    27601 ggcaaggtag tagttgcagg agatgacctt cctgccaagg tcgcagtgca agcaagtgct
    27661 gaaaaccaag aattggaaga agctatggaa gccatgttgg ctctgggcta caaggcaaca
    27721 gagctcaaga aaatcaagaa attctttgaa ggaacgacag atacagctga gaactatatc
    27781 aagtcggccc ttaaaatgtt ggtcaaatag gagcagagaa tgacaaaacg ttgttcgtgg
    27841 gtcaagatga caaacccgct ctacatcgcc tatcatgatg aggagtgggg tcagcccctc
    27901 catgatgacc aagcattgtt tgagttgttg tgtatggaaa cctatcaggc aggcctgtct
    27961 tgggaaacgg tactcaacaa acgccaagct ttccgagaag cctttcatag ctatcaaatt
    28021 cactcagtcg cagagatgac tgagactgaa ttggaagcca tgctggagaa tccagctatc
    28081 attcgaaata gagccaagct ttttgctaca cgcgctaacg cccaagtcct tctacagtta
    28141 caggcagagt acggctcttt tgatgcctat ctttggtctt ttgttgaggg gaaaattgtc
    28201 gttaacgatg ttcctgatta tcgccaagcg ccagctaaaa cacccttatc tgagaaatta
    28261 gccaaagatc tcaaaaaacg aggcttcaag ttcacaggcc cagtcgccgt attgtctttt
    28321 ctacaggctg cagggctagt tgatgaccac gagaatgatt gtgagtggaa aggtcttaaa
    28381 tgatgtctaa caaaaataag ggaattctga tttttgcgat tctctataca gtcctctttg
    28441 tgtttgatgg cgttaaattg ctggcttctt taatgccatc tgtcattgca aattatcttg
    28501 tttatgtagt tttagcttta tatggctcct tcttgttcaa ggatagattg atccaacaat
    28561 ggaaggagat tagaaagact aaaagaaaat tcttctttgg cgtcttaaca ggatggctct
    28621 ttctcattct gatgactgtt gtctttgaat ttgtatcaga gatgttgaag cagtttgtgg
    28681 gactagatgg acaaggtcta aatcagtcta atattcaaag tacctttcaa gaacaaccac
    28741 tactgatagc tgtttttgct tgtgtcattg gacctctggt agaagaatta tttttccgtc
    28801 aggtcttatt gcattacttg caggaacggt tgccaggttt actaagcatt attctggtag
    28861 gacttgtttt tgctctgact catatgcaca gtttggctct atcagagtgg attggtgcag
    28921 ttggttactt aggtggaggc cttgcctttt ctattattta tgtgaaagaa aaagagaata
    28981 tctactatcc cctacttgtt cacatgttaa gcaacagcct ctccttaatc attttagcta
    29041 tca
//
LOCUS       DBEJKC010000025        27921 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.025, whole genome shotgun sequence.
ACCESSION   DBEJKC010000025 DBEJKC010000000
VERSION     DBEJKC010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 27921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27921
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.025"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            143..2125
                     /locus_tag="ACL3G6_001123"
     CDS             143..2125
                     /locus_tag="ACL3G6_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0545666.1"
                     /translation="MKSSRLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSEEQKTSTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVVIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2426..7729
                     /locus_tag="ACL3G6_001124"
     CDS             2426..7729
                     /locus_tag="ACL3G6_001124"
                     /EC_number="3.2.1.97"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033926 -
                     endo-alpha-N-acetylgalactosaminidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpGH101 family
                     endo-alpha-N-acetylgalactosaminidase"
                     /protein_id="HGR0545667.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPRAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGTTTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKVTFLVTGAETGD
                     TWVGIYSTGNASNTRSDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVAED
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEATEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSNQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(7896..10055)
                     /gene="pbp1a"
                     /locus_tag="ACL3G6_001125"
     CDS             complement(7896..10055)
                     /gene="pbp1a"
                     /locus_tag="ACL3G6_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1A"
                     /protein_id="HGR0545668.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(10052..10648)
                     /gene="recU"
                     /locus_tag="ACL3G6_001126"
     CDS             complement(10052..10648)
                     /gene="recU"
                     /locus_tag="ACL3G6_001126"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HGR0545669.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10714..11241
                     /locus_tag="ACL3G6_001127"
     CDS             10714..11241
                     /locus_tag="ACL3G6_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HGR0545670.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGTLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            11311..11640
                     /gene="gpsB"
                     /locus_tag="ACL3G6_001128"
     CDS             11311..11640
                     /gene="gpsB"
                     /locus_tag="ACL3G6_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HGR0545671.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            11661..12041
                     /gene="rnpB"
                     /locus_tag="ACL3G6_001129"
     ncRNA           11661..12041
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACL3G6_001129"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            12126..13283
                     /locus_tag="ACL3G6_001130"
     CDS             12126..13283
                     /locus_tag="ACL3G6_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HGR0545672.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQIENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLCSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            13296..14690
                     /gene="mapZ"
                     /locus_tag="ACL3G6_001131"
     CDS             13296..14690
                     /gene="mapZ"
                     /locus_tag="ACL3G6_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HGR0545673.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEKV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            14766..16190
                     /gene="gndA"
                     /locus_tag="ACL3G6_001132"
     CDS             14766..16190
                     /gene="gndA"
                     /locus_tag="ACL3G6_001132"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HGR0545674.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSHKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVYASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            16202..16891
                     /locus_tag="ACL3G6_001133"
     CDS             16202..16891
                     /locus_tag="ACL3G6_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0545675.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVAYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESVTETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            16989..17945
                     /gene="cbpC"
                     /locus_tag="ACL3G6_001134"
     CDS             16989..17945
                     /gene="cbpC"
                     /locus_tag="ACL3G6_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HGR0545676.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGQFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEPKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYFGNKWYYLNAGN
                     GDMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVNYNGEWVQ"
     gene            18067..18945
                     /gene="mvk"
                     /locus_tag="ACL3G6_001135"
     CDS             18067..18945
                     /gene="mvk"
                     /locus_tag="ACL3G6_001135"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HGR0545677.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFWVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            18927..19880
                     /gene="mvaD"
                     /locus_tag="ACL3G6_001136"
     CDS             18927..19880
                     /gene="mvaD"
                     /locus_tag="ACL3G6_001136"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HGR0545678.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            19867..20874
                     /locus_tag="ACL3G6_001137"
     CDS             19867..20874
                     /locus_tag="ACL3G6_001137"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HGR0545679.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            20858..21868
                     /gene="fni"
                     /locus_tag="ACL3G6_001138"
     CDS             20858..21868
                     /gene="fni"
                     /locus_tag="ACL3G6_001138"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HGR0545680.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDNS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            21945..22643
                     /gene="liaF"
                     /locus_tag="ACL3G6_001139"
     CDS             21945..22643
                     /gene="liaF"
                     /locus_tag="ACL3G6_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HGR0545681.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            22640..23635
                     /locus_tag="ACL3G6_001140"
     CDS             22640..23635
                     /locus_tag="ACL3G6_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0545682.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FFFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            23649..24281
                     /locus_tag="ACL3G6_001141"
     CDS             23649..24281
                     /locus_tag="ACL3G6_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR0545683.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            24357..25050
                     /locus_tag="ACL3G6_001142"
                     /pseudo
     CDS             24357..25050
                     /locus_tag="ACL3G6_001142"
                     /inference="COORDINATES: protein motif:HMM:NF020296.4"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            25200..25439
                     /locus_tag="ACL3G6_001143"
     CDS             25200..25439
                     /locus_tag="ACL3G6_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545684.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            25520..26341
                     /gene="cbpG"
                     /locus_tag="ACL3G6_001144"
     CDS             25520..26341
                     /gene="cbpG"
                     /locus_tag="ACL3G6_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HGR0545685.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            26360..27382
                     /gene="cbpF"
                     /locus_tag="ACL3G6_001145"
     CDS             26360..27382
                     /gene="cbpF"
                     /locus_tag="ACL3G6_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HGR0545686.1"
                     /translation="MNLLKKMMQIALATFFFGLLATNTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEIALRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSQAEKRVYYFEDQRSYHTLKTGWI
                     YEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLNPATGI
                     MQTGWQYLGNRWYYLHSSGAMATGWYKEGSTWYYLDAENGDMRTGWQNLGNKWYYLRS
                     SGAMATGWYQESSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAINTTVGGYYLNY
                     NGEWVK"
     gene            complement(27510..>27921)
                     /locus_tag="ACL3G6_001146"
     CDS             complement(27510..>27921)
                     /locus_tag="ACL3G6_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGR0545687.1"
                     /translation="DGFNSEIIAYNLSTSPNLEQVQTMLEQAFTEKHYENTILHSDQG
                     WQYQHDSYHQFLEGKGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKTFKSLNQL
                     EQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
BASE COUNT         8540 a         5021 c         6415 g         7945 t
ORIGIN      
        1 tatagttgag ggatttttaa atgatattca tattttttgc aaagatgttg tttgaaaaat
       61 aattttcaaa aattctgaaa attctgttga caactttctg aaaagagtct ataatggaga
      121 gaaagtttta aaggagaaaa tgatgaaaag ttcaagacta tttgcccttg cgggcgtgac
      181 attattggcg gcgactactt tagctgcatg ctctggatca ggttcaagca ctaaaggtga
      241 gaagacattc tcatacattt atgagacaga ccctgataac ctcaactatt tgacaactgc
      301 taaggctgcg acagcaaata ttaccagtaa cgtggttgat ggtttgctag aaaatgatcg
      361 ctacgggaac tttgtgccgt ctatggctga ggattggtct gtatccaagg atggattgac
      421 ttacacttat actatccgta aggatgcaaa atggtatact tctgaaggtg aagaatacgc
      481 ggcagtcaaa gctcaagact ttgtaacagg actaaaatat gctgctgata aaaaatcaga
      541 tgctctttac cttgttcaag aatcaatcaa agggttggat gcctatgtaa aaggggaaat
      601 caaagatttc tcacaagtag gaattaaggc tctggatgaa cagacagttc agtacacttt
      661 gaacaaacca gaaagcttct ggaattctaa gacaaccatg ggtgtgcttg cgccagttaa
      721 tgaagagttt ttgaattcaa aaggggatga ttttgccaaa gctacggatc caagtagtct
      781 cttgtataac ggtccttatt tgttgaaatc cattgtgacc aaatcttctg ttgaatttgc
      841 gaaaaatccg aactactggg ataaggacaa tgtgcatatt gacaaagtta aattgtcatt
      901 ctgggatggt caagatacca gcaaacctgc agaaaacttt aaagatggta gccttacagc
      961 agctcgtctc tatccaacaa gtgcaagttt cgcagagctt gagaagagta tgaaggacaa
     1021 tattgtctat actcaacaag actctattac gtatctagtt ggtacaaata ttgaccgtca
     1081 gtcctataaa tatacatcta agaccagtga agaacaaaaa acatctacga aaaaggctct
     1141 cttaaacaag gatttccgtc aggctattgc atttggattt gaccgtacag cctatgcctc
     1201 tcagttgaat ggacaaactg gagcaagcaa aatcttacgt aatatctttg ttccaccaac
     1261 atttgttcaa gcagatggta aaaactttgg cgatatggtc aaagagaaat tggtcactta
     1321 tggggatgaa tggaaggatg ttaatcttgc agattctcag gatggtcttt acaatccaga
     1381 aaaagccaag gctgaatttg ctaaagctaa atcagcttta caagcagaag gtgtgacttt
     1441 cccaattcat ttggatatgc cagttgacca gacagcaact acaaaagttc agcgcgtcca
     1501 atctatgaaa caatccttgg aagcaacttt aggagcggat aatgtagtca ttgatattca
     1561 acaactacaa aaagacgaag taaacaatat tacatatttt gctgaaaatg ctgctggtga
     1621 agactgggat ttatcagata atgtcggttg gggtccagac tttgccgatc catcaaccta
     1681 ccttgatatc atcaaaccat ctgtaggaga aagtactaaa acatatttag ggtttgactc
     1741 aggggaagat aatgtagctg ctaaaaaagt aggtctatat gactacgaaa aattggttac
     1801 tgaggctggt gatgagacta cagatgttgc taaacgctat gataaatacg ctgcagccca
     1861 agcttggttg acagatagtg ctttgattat tccaactaca tctcgtacag ggcgtccaat
     1921 cttgtctaag atggtaccat ttacaatacc atttgcattg tcaggaaata aaggcacaag
     1981 tgaaccagtc ttgtataaat acttggaact tcaagacaag gcagtcactg tagatgaata
     2041 ccaaaaagct caggaaaaat ggatgaaaga aaaagaagag tctaataaaa aggctcaaga
     2101 agatctcgca aaacatgtga aataactgtt gcaaaatata agaaaggatt tagtatttcc
     2161 cttgaatgct gaatcctttt ttacatttgt aaagaaagat tctaaatgta ctgaccccca
     2221 aaagttggag cctctttttg tcagaataga gaaaattttt gttaatttta cttgtttcct
     2281 attgctttct cagctattat ttgttatatt aaaagcataa ttatttttta tttatcaggg
     2341 ttaagcattg cactttcaga ggaaggagta ttttttaaaa aggaaatgta aacgcttgct
     2401 aaaaaatgaa aggatttaga agtttatgaa taaaggatta tttgaaaaac gttgtaaata
     2461 tagtattcgg aaattttcat taggtgttgc ttctgttatg attggagctg cattctttgg
     2521 gacaagtccg gttcttgcag atagcgtgca gtctggttcc acggcgaact taccagctga
     2581 tttagctact gctcttgcaa cagcaaaaga gaatgatgga cgtgattttg aagcgcctaa
     2641 ggtgggagaa gaccaaggtt ctccagaagt tacagatgga cctaagacag aagaagaact
     2701 attagcactt gaaaaagaaa aaccggctga agaaaaacca aaagaggata aacctgcagc
     2761 tgctaaacct gaaacaccta agacggtaac ccctgaatgg caaacggtag agaaaaaaga
     2821 acaaaaggga acagtcacta tccgagaaga aaaaggtgtc cgctacaacc aactatcctc
     2881 aactgctcaa aatgataacg caggaaaacc agccctgttt gaaaagaagg gcttgaccgt
     2941 tgatgccaat ggaaatgcaa ctgttgattt aaccttcaaa gatgattctg aaaagggcaa
     3001 atcacgcttt ggtgtcttcc tgaaatttaa agataccaat aataatgttt ttgtcggtta
     3061 tgacaaggat ggctggttct gggagtataa atctccaaca actagcactt ggtatagagg
     3121 tagtcgtgtt gctgctcctg aaacaggatc aacaaaccgt ctctctatca ctctcaagtc
     3181 agacggtcag ctaaatgcca gcaataacga tgtcaatctc tttgacacag tgactctacc
     3241 agctgcggtc aatgaccatc ttaaaaatga gaagaagatc cttctcaagg cgggctctta
     3301 tggcaatgac cgtacggttg tcagcgttaa aacagacaat caagaaggcg taaaagcgga
     3361 tgatactcct gcccagaaag aaacaggtcc ggttgttgac gatagcaagg tgacttatga
     3421 tacgatccag tctaaggtac ttaaggcagt aattgaccaa gccttccctc gtgtcaagga
     3481 atacagcttg aacgggcata ctttgccagg acaggtgcaa cagttcaacc aagtctttat
     3541 caataaccac cgaatcaccc ctgaagtcac ttataagaaa atcaatgaga caacagcaga
     3601 gtacttgatg aagcttcgcg atgatgctca cttaatcaat gcggaaatga cagtacgcct
     3661 gcaagttgtg gacaatcaat tgcactttga tgtgaccaag attgtcaacc acaatcaagt
     3721 cactccaggt caaaagattg atgacgaaag aaaactactt tcttctatta gtttcctcgg
     3781 caatgcttta gtctctgttt ctagtgatca aactggtgct aagtttgatg gggcaaccat
     3841 gtcaaacaat acgcatgtca gcggagatga tcatatcgat gtaaccaatc caatgaaaga
     3901 cctagccaag ggttacatgt atggatttgt ttctacagat aagcttgctg ctggtgtttg
     3961 gagtaactct caaaacagct atggtggtgg ttcgaatgac tggactcgtt tgacagctta
     4021 taaagaaaca gtcggaaatg ccaactatgt aggaatccac agctctgaat ggcaatggga
     4081 aaaagcttat aagggcattg ttttcccaga atacacgaag gaacttccaa gggctaaggt
     4141 tgttatcact gaagatgcca atgcagacaa gaaagtcgat tggcaggatg gtgccattgc
     4201 ttatcgtagc attatgaaca accctcaagg ttgggaaaaa gttaaggata tcacagctta
     4261 ccgtatcgcg atgaactttg gttctcaagc acaaaaccca ttccttatga ccttggatgg
     4321 tatcaagaaa atcaatctcc acacagatgg tcttgggcaa ggtgttctcc ttaaaggata
     4381 tggtagcgaa ggccatgact ctggtcactt gaactatgct gatattggta agcgtatcgg
     4441 tggtgtcgaa gacttcaaga ccctgattga gaaggctaag aaatatggag ctcatctagg
     4501 tatccacgtt aacgcttcag aaacttatcc tgagtctaaa tacttcaatg aaaaaattct
     4561 ccgtaagaat ccagatggaa gctatagcta tggttggaac tggctagatc aaggtatcaa
     4621 cattgatgct gcctatgacc tagctcatgg tcgtttggca cgttgggaag atttgaagaa
     4681 aaaacttggt gacggtctcg actttatcta tgtggacgtt tggggtaatg gtcaatcagg
     4741 tgataacggt gcctgggcta cccacgttct tgctaaagaa attaacaaac aaggctggcg
     4801 ctttgcgatc gagtggggcc atggtggtga gtacgactct accttccatc actgggcagc
     4861 tgacttgacc tacggtggct acaccaataa aggtatcaac agtgccatca cccgctttat
     4921 ccgtaaccac caaaaagatg cttgggtagg ggactacaga agttatggtg gtgcagccaa
     4981 ctatccactg ctaggtggct acagcatgaa agactttgaa ggctggcaag gaagaagtga
     5041 ctacaatggc tatgtgacta acctctttgc tcatgacgtc atgactaagt acttccaaca
     5101 cttcactgta agtaaatggg aaaatggtac accggtgact atgaccgata acggtagcac
     5161 ctataaatgg actccagaaa tgcgagtgga gttggtagat gctgacaata ataaagtagt
     5221 tgtaactcgt aagtcaaatg atgtcaatag cccacaatat cgcgaacgta cagtaacgct
     5281 caacggacgt gtcatccaag atggttcagc ttacttgact ccttggaact gggatgcaaa
     5341 tggtaagaaa ctttctactg agaaggaaaa gatgtactac ttcaatacgc aggccggtac
     5401 aacaacttgg acccttccaa gcgattgggc aaagagcaag gtttaccttt acaagctaac
     5461 tgaccaaggt aagacagaag agcaagaact aactgtaaaa gatggtaaaa ttaccctaga
     5521 tcttctagca aatcaaccat acgtacttta ccgttcaaaa caaaccaatc ctgaaatgtc
     5581 atggagtgaa ggcatgcaca tctatgacca aggatttaat agtggaacct tgaaacactg
     5641 gaccatttca ggcgatgctt ctaaggcaga aattgtcaag tctcaagggg caaacgatat
     5701 gcttcgtatt caaggaaaca aagaaaaagt tagtctcact cagaaattaa ctggcttgaa
     5761 accaaatacc aagtatgccg tttatgtcgg tgtcgataac cgtagtaatg ccaaggcaag
     5821 tatcactgtg aatactggtg aaaaagaagt gactacttat accaataagt ctctcgccct
     5881 caactatgta aaagcctacg cccacaatac acgtcgtaac aatgctacag ttgacgatac
     5941 aagttacttc caaaacatgt acgccttctt tacaactgga tcggacgtct caaatgttac
     6001 tctgacattg agtcgtgaag ctggtgatca agcaacttac tttgatgaaa ttcgtacctt
     6061 tgaaaacaat tcaagcatgt acggagacaa gcatgataca ggtaaaggca ccttcaagca
     6121 agactttgaa aatgttgctc agggtatctt cccatttgta gtgggtggtg ttgaaggtgt
     6181 tgaagataac cgcactcact tgtctgaaaa acacgatcca tatacacaac gtggttggaa
     6241 tggtaagaaa gtcgatgatg ttatcgaagg aaattggtca ctcaagacaa atggactagt
     6301 gagccgtcgt aacttggttt accaaactat tccgcaaaac ttccgttttg aagcaggtaa
     6361 gacctaccgt gtaacctttg aatacgaagc aggttcagac aatacctatg cttttgtagt
     6421 cggtaaggga gaattccagt caggtcgtcg tggtactcaa gcaagcaact tggaaatgca
     6481 tgaattgcca aatacttgga cagattctaa gaaagccaag aaggtaacct tccttgtgac
     6541 aggtgcagaa acaggggata cttgggtagg tatctactca actggcaatg caagtaatac
     6601 tcgtagtgat tctggtggaa atgccaactt ccgtggttat aacgacttca tgatggataa
     6661 tcttcaaatc gaagaaatta ccctaacagg taagatgttg acagaaaatg ctctgaagaa
     6721 ctacttgcca acggttgcca tgactaacta caccaaagag tctatggatg ctttgaaaga
     6781 ggcggtcttt aacctcagtc aggccgatga tgatatcagt gtggaagaag cgcgtgcaga
     6841 gattgccaag attgaagcct tgaagaatgc tttggttcag aagaaaacgg ctttggtagc
     6901 agaagacttt gcaagtctta cagctcctgc tcaggctcaa gaaggtcttg caaatgcctt
     6961 tgatggaaac ttatctagtt tatggcatac atcatggggc ggaggagatg taggcaagcc
     7021 tgcaaccatg gtcttgaaag aagcaactga aatcactgga cttcgttatg ttccacgtgg
     7081 atcaggttca aatggtaact tgcgtgatgt gaaacttgtt gtgacagatg agtctggcaa
     7141 ggagcatacc tttactgcaa ctgattggcc agataacaat aagccaaaag acattgattt
     7201 tggtaagaca attaaggcta agaaaattgt ccttacaggt actaagactt acggagatgg
     7261 tggcgataaa taccaatctg cagcggaact tatctttact cgtccacagg tagcagaaac
     7321 acctcttgac ttgtcaggct atgaagcagc tttggctaag gctcagaaat taacagacaa
     7381 agacaatcaa gaggaagtag ctagcgttca ggcaagcatg aaatatgcga cggataacca
     7441 tctcttgacg gaaagaatgg tggaatactt tgcagattat ctcaaccaat taaaagattc
     7501 tgctacgaaa ccagatgctc caactgtaga gaaacctgag tttaaactta gctctttagt
     7561 ttccaatcaa ggtaagacgc cagattataa gcaagaaata gatagaccag aaacacctga
     7621 acaaatcttg ccagcaacag gtgagagtca atctgacaca gccctcttcc tagcaagtgt
     7681 tagtctagcc ctatctgctc tctttgtagt aaaaacgaag aaagactagt atttagtaaa
     7741 acctcttaac aagattacgg aagcagtctc tatcttttcc aatgaggttt atagtacaga
     7801 aaaagcctga gaagatgtct tctcaggctt ttgttaagca cataaataca atagtgctat
     7861 gacaaaatca cccagaaaaa tctgggtgat aaatgttatg gttgtgctgg ttgaggattc
     7921 tgattttgtt gatcaggggt tgtatttgat tgttgcgtat tattgttagg attggtagtc
     7981 gtactattat ttgtgcttgg agtggttgag ctagactgtg aagttgaact atctgatgat
     8041 gagcttgaac tttcagttga tgggggttgt tgtggagcag gtgagttcca cgtagaacga
     8101 gcaccatttt taaatacgaa ttctccattt ctgtagagcc cctctggtat attccaatcc
     8161 tctggattgc ttccttcaga cagataggtc atcatagagc ggtaaacttt ggcagcgacc
     8221 gtaagaccat tgcctacaag tggtgtcaga cggttagaat agcctgtcca tacagccatt
     8281 gaatatttac gcgtatagcc agcaaatagt tcatcaggtg ctacaaattg agaggtcttg
     8341 atgtggtttt caatttcctc gtctgtatag ttagaggttc ctgttttacc agcctgaggg
     8401 agccaagcaa gataggcatt tcgtccagtt ccataactca agactgtttt catcatgtcg
     8461 gtcatcatat aggctgtcgt ttccttcatg gcacgagttc cgacattaga gaactctttt
     8521 tcactcccat cactaaagac gactttatgg atatacattg gtttatagta agttccacca
     8581 tttgcaaagg cagcgtaagc agcagccatc ttttcactac ttgctccata ttttttgtct
     8641 gattcggttg tgttacttga aatggcattt gagtagtgaa tacttgggta gtcgattccg
     8701 agaccattta ggaaagtctt ggcgcggttg agtccgacct tgtttagagt ttccacggct
     8761 gggacgtttc gcgattgttg cagggcgtat tgcaaggtga tgttgccaaa gtagccccta
     8821 tcccagttat aaacaggggt atttgtccca gggtagttat agggctcatc gtgaacgata
     8881 gtagcagttg aatcgtagat accgtactcc aaggcaggag catagtctgt gatcggtttc
     8941 atagttgatc cccagtcgcg gtttgtttct actgcttggt taattccgaa ggaaacatta
     9001 cttgactgat ggcgtgctcc tagctgggca atgactttac cgttagaaac atcaacaatg
     9061 gtagaagcga cttgcaattc atcgtctgga taggcaacgt attcgtctgt attgtaaata
     9121 tcccacagat gtttttgagc ttcttggtct acatttgtgt agacatccat cccagttgtg
     9181 agcaggttat agcctgtttc ttcttcaact tgattgatga cttccttgag gtaattatcc
     9241 atgtaagcag ggtaattact tgctgatttg agactttgta gtccatcagt aattggtgta
     9301 ttgactgctt tctcatactg ttcagcagag atgtagcctt gatttttcat ttcagataag
     9361 accaagtttc ggcggtcttg ggctgcttct ggatgtgaat aggggtcata ttggtttggt
     9421 gcctgaggca ttccagccag caaggctaac tgaggtaaac ttaaattatt gaggtcttta
     9481 ccatagtagt tttgagctgc tgtctgcatt ccatagttcc cattagacat gtagacctta
     9541 tttatatagt aggtcaagat ttcttgcttg gttgcttttt gttctaactg aatcgctaac
     9601 caagcttcct gagccttacg agaaatagtc tggtcggaag tcgaagttga aaagtaagtc
     9661 aacttaatca actgttgagt gagagttgat ccaccttgga gggaattgct ttgcagattg
     9721 cgcaagaaag ctcccaggat acggatggta tcaatccccc tgtggtcgaa gaagcgatgg
     9781 tcttcgatag aaacgattgc tttaaccaaa tctgtgggaa tatcattagc ttgggcattg
     9841 acgcggcgtt cagaacccaa gtcagcaatg agttgatttt tattgtcgta gattttacta
     9901 gaagttgttg caactagttt actctcggat aggctaggag ccttgctaac gtagtagaaa
     9961 aaaactcctc cgcctaagac aatggctgcg ataaccaagc ttaagaagct aatgctcaga
    10021 tacttgatta ggcgcagaat cgttggtttg ttcatcttgt tttaccacct aataaatgtt
    10081 ctttgataac attgagataa ggaatttgag ggaaggcacc agccttgatt tcatatccat
    10141 attctcgaat atattcaagt ggcattgatt tttgtccctt atcttgatga tagaagcgaa
    10201 tcaaatcgaa tgccggcaat aagtaggttt cttgctgaga agaaaagtga agaaggacaa
    10261 agcagattcc ttgttgggca aggacttgtt ccatatgctg aatctgatgt ggatgaaaat
    10321 ttttcatcgg aatcgcacgt ttttgttttg tttccttgac ttcaaagtcg atgtaatatc
    10381 cattataaac gccagaatag tccgtcgttg aagcttgtcg aaaataggct tcaacaatct
    10441 tggcacgact tcgttgtgga tagtccactt gtacgatttg aataggagtt ggtttcttat
    10501 gtataacagc caagccctga gacaaatagt agtcgttggt agcattgatc atcttttcaa
    10561 aagacattcc tcgatttgcg aaatttttgg gttgagaaag agatgtttgt cttttttgtg
    10621 atgaaacttt atgtggatag ttgaccataa ttctccttat tggtacaata acatcacttt
    10681 attataccat aatttgcaca gaaagggtta aaaatggcta cagctttggt tttaggctat
    10741 tctgcttttg atttgggttt attttctgat aaggatcctc gtcttaaatt gattaaaaaa
    10801 gcgatacgta aagatttaga ggctatggca gcagatgggg tgtcttggct tgtgtttaca
    10861 gggactttgg gctttgaata ttgggtttta gaggttgctc aggagatgaa aaccgaatac
    10921 ggtttccagt tggccaccat ttttgctttt gaaacccatg gggaaaattg gaatgaaggc
    10981 aatcagatga aactgagtcg ctttaagcag gtagactttg tcaaatatgc ctatcctcgc
    11041 tatgaacaca aggggcagtt aagagattac cagcagtttt tgctggaaaa cacgactagt
    11101 tcctatcttt tttatgatga agaaaatgaa acaaaactag cttattttta ccaaaagatg
    11161 aaaaatcaag aggactattt tataaagaga ttaacatttg atcaattaaa tgaacttgct
    11221 gaaaattttt ccgaaaattg aagctttgac cttgattttt gtttgccttt ttttatataa
    11281 taatactagc aagcgagaat ggagagagac atggcaagta ttattttttc agcgaaagat
    11341 atttttgaac aagagtttgg acgtgaagtc cgtggctata ataaagtaga agttgacgag
    11401 tttttagacg atgtcatcaa ggactatgaa acctatgctg ccttggtcaa gtcacttcgt
    11461 caggaaattg cggatttgaa ggaagaatta actcgtaaac cgaaaccttc accagttcaa
    11521 gcagaacccc ttgaagcggc aattacaagt tctatgacga attttgatat tttgaaacgc
    11581 ctgaatagat tggaaaaaga agtttttggt aaacaaattt tagataactc agatttttaa
    11641 gtagttattt gagatgtgca atttttggat aatcgcgtga ggagaattgc ttctcatgag
    11701 gaaagtccat gctagcacag gctgtgatgc ctgtagtgtt tgtgctaggc gaaaccataa
    11761 gcctagggac gagaaatcgt tacggcagtt gaaatggcta agtccttgga taggccagag
    11821 taggcttgaa agtgccacag tgacgaagtc tttctggaaa cagagagagt ggaacgcggt
    11881 aaacccctca agctagcaac ccaaattttg gtcggggcat ggagtacgcg gaaacgaacg
    11941 tagtattctg actgctatca gctagagctg ttagtggtag acagatgatt atcgaaggaa
    12001 gtggtcctag tcacttctgg aacaaaacat ggcttataga aaattgcata taggttgggg
    12061 ctgagaaatt ttctcaacct cattttttaa agtggacata tagaaaggtc ttgcaagact
    12121 gtaacatgaa aaaagaattt aatttaattg caactgtggc agcagggctt gaggctgtcg
    12181 ttggtcgtga agtgcgagag ttgggctacg attgtcagat tgaaaatgga cgtgttcgtt
    12241 ttcaaggaga cgtgagagct attatcgaaa ccaacctttg gctgcgggca gcagatcgta
    12301 tcaaaattat cgtaggaacg ttccctgcta agacttttga agagctattt cagggagttt
    12361 tcgctttaga ttgggaaaat tatttaccac ttggagctcg gttcccgatt tcaaaagcta
    12421 aatgtgttaa gtccaaactt cacaatgagc ccagtgttca ggctatttct aagaaagctg
    12481 ttgtcaagaa attgcagaaa cactatgctc gcccagaagg ggttcctctg atggagaatg
    12541 gcccagagtt taagattgag gtctctattc tcaaagatgt ggcaactgtc atgattgata
    12601 cgaccgggtc tagcctcttt aaacgtggtt atcgtaccga aaaaggtggc gctcctatca
    12661 aggaaaatat ggcagcagcc attttacaac tttctaactg gtatccagac aagcctttga
    12721 ttgatccgac ctgtggttcg gggactttct gtattgaggc agttatgatt gctagaaaga
    12781 tggcgccagg tcttcgtcgc tcttttgcat ttgaggaatg gaactggatc agcgatcgct
    12841 tgattcaaga agtgcgcaca gaagcggcta aaaaagtaga ccgtgagctt gagctggata
    12901 tcatgggctg tgatattgat gctcgcatgg tggaaattgc taaggccaat gctcaggcag
    12961 ctggtgttgc aggagacatt acttttaagc agatgcgcgt gcaggattta tgttccgata
    13021 aaatcaatgg agtaatcatt tccaatccgc cttatggtga acgtttgtca gatgatgcag
    13081 gggtgaccaa gctctatgct gagatggggc aagtatttgc accgctgaaa acttggagca
    13141 aatttatcct gactagtgat gaagcttttg aaagcaagta tggtagccaa gcagataaga
    13201 agcgtaagtt atacaacgga accttgaaag tggatctgta tcaatatttt ggtcagcgtg
    13261 tcaaacggca agaggtaaaa tagaaaggga tactcatgag taaaaaaaga cgaaatcgtc
    13321 aaaaaaaaga aggtcaagaa ccgcaatttg attttgatga agcaaaagag ctaacagttg
    13381 gtcaagctat tcgtaaaaat gaagaagtgg aagcaggagt cttgcctgag gattccattt
    13441 tggacaagta tgttaagcaa cacagagatg aaattgaggc ggataagttt gcgactcgtc
    13501 aatacaaaaa agaggagttc gttgaaactc agagtctgga tgatttaatt caagagatgc
    13561 gtgaggctgt agagaagtca gaagcttctt cggagaaagt tccatcttct gaagacatct
    13621 tactaccctt gcctctggac gatgaggagc aaggcttgga tcctctattg ctagatgatg
    13681 aaaatccaac agaaatgact gaagaagtgg aagaggagca aaacctttct cgtctggatc
    13741 aagaggactc agaaaagaaa agtaaaaaag gctttatttt gaccgttttg gcgcttgtat
    13801 cagtaattat ttgtgtcagt gcttattatg tctaccgtca agtggctcgt tcgaccaagg
    13861 aaattgaaac ttctcaatca actacagcca atcaatcgga tgtggatgat tttaatacac
    13921 tttatgacgc cttttacaca gatagcaata aaacggcttt gaaaaatagc cagtttgata
    13981 aactgaatca actcaagact ttacttgata agctggaagg tagtcgtgaa catacgcttg
    14041 ccaaatctaa atatgatagt ctagcaacgc aaatcaaggc tattcaagat gtcaatgctc
    14101 aatttgagaa accagctatt gtggatggtg tgttggatac caatgccaaa gccaaatcgg
    14161 atgctaaatt tacggatatt aaaactggaa atacggagct tgataaagtg ctagataagg
    14221 ctatcagtct tggtaagagc cagcaaacaa gtacttctag ctcaagttca agtcaaacta
    14281 gcagctcaag ttcaagtcaa gcaagttcaa atacgactag tgagccaaaa ccaagtagtt
    14341 caaatgagac tagaagtagt cgcagtgaag tcaatatggg tctctcgagt gcaggggttg
    14401 ctgttcaaag aagtgccagt cgtgttgcct ataatcagtc tgctattgat gatagtaata
    14461 actctgcctg ggattttgcg gatggtgtct tggaacaaat tctagcgact tcacgttcac
    14521 gtggctatat cactggagac caatatatcc ttgaacgtgt caatatcgtt aacggcaatg
    14581 gttattacaa cctctataag ccagatggaa cctatctctt tacccttaac tgtaagacag
    14641 gctactttgt cggaaatggc gctggtcatg cggatgactt ggactactaa gcagtcgtta
    14701 caaaattctt tcttttcaaa agtaaaaatg ataaaataaa acaaatgaaa caagaggagt
    14761 gtcaaatgac aaaagctaac tttggtgtcg taggtatggc cgtaatgggt cgtaaccttg
    14821 cccttaatat tgaatcacgt ggttacacag ttgctatcta caaccgtagt aaagaaaaaa
    14881 cggaagatgt gattgcttgc catcctgaaa agaattttgt accaagctat gacgttgaaa
    14941 gttttgtaaa ctcaatcgaa aaacctcgtc gtatcatgct gatggttcaa gctggacctg
    15001 gtacagatgc tactatccaa gcccttcttc cacaccttga caagggtgat atcttgattg
    15061 acggaggaaa cactttctac aaagatacca tccgtcgtaa tgaagaattg gcaaactcag
    15121 gtatcaactt tatcggtact ggagtttctg gtggtgaaaa aggtgccctt gaaggtcctt
    15181 ctatcatgcc tggtggacaa aaagaggcct acgaattggt tgcggatgtt cttgaagaaa
    15241 tctcagctaa agcaccagaa gatggcaaac catgtgtgac ttacatcggc cctgatggag
    15301 ctggtcacta tgtgaaaatg gttcacaatg gtattgagta cggtgatatg caattgatcg
    15361 cagaaagcta tgacttgatg caacacttgc taggcctttc tgcagaggat atggctgaaa
    15421 tctttactga gtggaacaag ggtgaattag acagctattt gatcgaaatc acagctgata
    15481 tcttgagcca taaagacgat gaaggccaag atggaccaat cgtagactac atccttgatg
    15541 ctgcaggtaa caagggaact ggtaaatgga ctagccaatc atctcttgac cttggtgtac
    15601 cattgtcact gattactgag tcagtgtttg cacgctacat ttcaacttac aaagaagaac
    15661 gtgtatatgc tagcaaggtg cttccaaaac cagctgcctt caactttgaa ggagacaagg
    15721 ctgaattgat tgaaaagatc cgtcaagccc tttacttctc aaaaatcatt tcatacgcac
    15781 aaggatttgc tcaattgcgt gtagcctcta aagaaaacaa ctggaacttg ccatttgcag
    15841 atatcgcatc tatctggcgt gatggctgta tcatccgttc tcgtttcttg caaaagatta
    15901 cagatgctta caaccgcgat gcagatcttg ccaaccttct tttggacgag tacttcttgg
    15961 atgttactgc taagtatcaa caagcagtgc gtgatatcgt agctcttgcg gttcaagctg
    16021 gtgtgccagt gccaactttc tcagcagcta ttacttactt tgatagctac cgttcagctg
    16081 accttccagc taacttgatc caagcacaac gtgactactt tggtgctcac acttaccaac
    16141 gtaaagacaa agaaggaacc ttccactact cttggtatga cgaaaaataa gtaggtcagc
    16201 catggggaaa cggattttat tacttgagaa agaacgaaat ctagctcatt ttttaagttt
    16261 ggaactccag aaagagcagt atcgggttga tctggtagag gaggggcaaa aagccctctc
    16321 catggctctt cagacagact atgatttgat gttattgaac gttaatctgg gagatatgat
    16381 ggctcaggat tttgcagaaa aattgagtcg aactaaacct gcctcagtca tcatgatttt
    16441 agatcattgg gaagacttgc aagaagagct ggaagttgtt cagcgttttg cagttgcata
    16501 catttataag ccagtcctta tcgaaaatct ggtagcgcgt atttcggcga tcttccgagg
    16561 tcgggacttc attgatcaac actgcagtct gatgaaagtt ccaaggactt accgcaatct
    16621 taggatagat gttgaacatc acacggttta tcgtggtgaa gagatgattg ctctgacccg
    16681 ccgtgagtat gaccttttgg cgacacttat gggaagcaag aaagtattga ctcgtgagca
    16741 attgttggaa agtgtttgga agtatgaaag tgtgaccgag acaaatatcg tagatgtcta
    16801 tatccgctat ctacggagca agcttgatgt taaaggccaa aaaagctaca ttaaaaccgt
    16861 gcgtggtgtt ggatatacca tgcaagaata gataagcagt tgcagttgtg taactgcttt
    16921 tttgaggagt ttttatatat tgacatgcag tcgggtcttt gctacaatcg ttttaggagg
    16981 atatatagat gaaacttttg aaaaaaatga tgcaagttct actagcagtc tttttctttg
    17041 gtttgctagc tacaaatacg gtatttgcga ataccacagg tggccaattt gttgataagg
    17101 ataatagaaa atattatgta aaagatgatc ataaagcaat ctattggcat aaaatagacg
    17161 gtaaaactta ctattttggt gatattggag agatggttgt cggttggcaa tacttagaaa
    17221 ttcctggaac aggttatcgt gataatttat tcgataacca accagttaat gagattggcc
    17281 ttcaggagaa gtggtactat tttggacaag atggtgcttt gctagaacaa acagataaac
    17341 aagtactaga gccaaaaacg tctgaaaata caggaaaagt atacggtgaa caatatcctc
    17401 tatctgctga aaagagaact tattattttg ataataatta tgctgtaaag acaggctgga
    17461 tttatgaaga cggcaattgg tattatttaa ataagctagg aaattttggc gatgattctt
    17521 acaatccact accaattggt gaagttgcta agggttggac tcaagatttt catgttacta
    17581 ttgacattga tagaagcaaa cctgctccat ggtactacct agatgcttca ggtaagatgc
    17641 ttacagattg gcaaaaagta aacggaaaat ggtattattt tggctcctct ggttctatgg
    17701 caacaggttg gaaatatgta cgaggcaaat ggtattactt agataataaa aatggtgata
    17761 tgaaaacagg atggcaatac tttggtaaca agtggtacta cctaaatgca ggtaatggag
    17821 acatgacgac aggttggttc caggtcaatg gcagatggta ctacgcttat agctcaggtg
    17881 ccttggcagt gaatacgacc gtagatggct attctgtcaa ctataatggc gaatgggttc
    17941 aataatgaaa gaagcgattg tgaatggaaa caatcgcttt ttttgtgaaa atataataaa
    18001 atagatagga aagaattaat acttgtatga aaaataagac gttttttcgt ctagtaaaag
    18061 gaaaaaatga caaaaaaagt tggtgtcggt caggcacata gtaagataat tttaataggg
    18121 gaacatgcgg tcgtttacgg ttatcctgcc atttccctgc ctcttttgga ggtggaggtg
    18181 acctgtaagg tagttcctgc agagagtcct tggcgccttt atgaggagga taccttgtcc
    18241 atggcggttt atgcctcact ggagtatttg aatatcacag aagcctgcat tcgttgtgag
    18301 attgactcgg ctatccctga gaaacggggg atgggttcgt cagcggctat cagcatagcg
    18361 gccattcgtg cagtatttga ctactatcag gctgatctgc ctcatgatgt actagaaatc
    18421 ttggtcaatc gagctgaaat gattgcccat atgaatccta gtggtttgga tgctaagacc
    18481 tgtcttagtg accaacctat tcgctttatc aagaacgtag gatttacaga acttgagatg
    18541 gatttatccg cctatttggt gattgccgat acgggtgttt atggtcatac tcgtgaagcc
    18601 atccaagtgg ttcaaaataa gggcaaggat gccctaccgt ttttgcatgc cttgggagaa
    18661 ttaacccagc aagcagaagt tgcgatttca caaaaagatg ctgaaggact gggacaaatc
    18721 ctcagtcaag cgcatttaca tttaaaagaa attggagtca gtagccctga ggcagacttt
    18781 tgggttgaaa cgactcttag ccatggtgct ctgggtgcca agatgagcgg tggtgggcta
    18841 ggaggttgta tcatagcctt ggtaaccaat ttgacacacg cacaagaact agcagaaaga
    18901 ttagaagaga aaggagctgt tcagacatgg atagagagcc tgtaacagta cgttcctacg
    18961 caaatattgc tattatcaaa tattggggaa agaaaaaaga aaaagagatg gtgcctgcta
    19021 ctagcagtat ttctctaact ttggaaaata tgtatacaga gacgaccttg tcgcctttac
    19081 cagccaatgt aacagctgac gaattttaca tcaatggtca gctacaaaat gaggtcgagc
    19141 atgccaagat gagtaagatt attgaccgtt atcgtccagc tggtgagggc tttgtccgta
    19201 tcgatactca aaacaatatg cctacggcag cgggtctgtc ctcaagttct agtggtttgt
    19261 ccgccctggt caaggcttgt aatgcttatt tcaagcttgg attggataga agtcagttgg
    19321 cacaggaagc caaatttgcc tcaggttctt cttctcggag tttttatgga ccactaggag
    19381 cctgggataa ggatagtgga gaaatttacc ctgtagagac agacttgaaa ctagctatga
    19441 ttatgttggt gctagaggac aagaaaaaac caatctctag ccgtgacggg atgaaacttt
    19501 gtgtggaaac ctcgacgact tttgacgact gggttcgtca gtctgagaag gactatcagg
    19561 atatgctgat ttatctcaag gaaaatgatt ttgccaagat tggagaatta acggagaaaa
    19621 atgccctggc tatgcatgct acgacaaaga ctgctagtcc agccttttct tatctgacgg
    19681 atgcctctta tgaggctatg gactttgttc gccagcttcg tgagaaagga gaggcctgct
    19741 actttaccat ggatgctggt cccaatgtta aggtcttctg tcaggagaaa gacttggagc
    19801 atttatcaga aattttcggt catcgttatc gcttgattgt gtcaaaaaca aaggatttga
    19861 gtcaagatga ttgctgttaa aacttgcgga aaactctatt gggcaggtga atatgctatt
    19921 ttagagccag ggcagttagc tttgataaag gatattccca tctatatgag ggctgagatt
    19981 gctttttctg acagctaccg tatctattca gatatgtttg atttcgcagt ggacttaagg
    20041 cctaatcctg actacagctt gattcaagaa acgattgctt tgatgggaga cttcctcgct
    20101 gttcgcggtc agaatttaag acctttttcc ctaaaaatct gtggcaaaat ggaacgagaa
    20161 gggaaaaagt ttggtctagg ttctagtggc agcgtcgttg tcttggttgt caaggcttta
    20221 ttggctctct ataatctttc ggttgatcag gagctcttgt tcaagctgac tagcgctgtc
    20281 ttgcttaagc gaggagacaa tggttccatg ggcgaccttg cctgtattgt ggcagaggat
    20341 ttggttctct accagtcatt tgatcgccag aaggcggctg cttggttaga agaagaaaac
    20401 ttggcgacag ttctggagcg tgattgggga ttttttatct cacaagtgaa accaacttta
    20461 gaatgtgatt tcttagtggg atggaccaag gaagtggctg tatcgagtca catggtccag
    20521 caaatcaagc aaaatatcaa tcaaaatttt ttaagttcct caaaagaaac ggtggtttct
    20581 ttggtcgaag ccttggagca ggggaaagcc gaaaaagtta tcgagcaagt agaagtagcc
    20641 agcaagcttt tagaaggctt gagtacagat atttacacgc ctttgcttag acagttgaaa
    20701 gaagccagtc aagatttgca ggccgttgcc aagagtagtg gtgctggtgg tggtgactgt
    20761 ggcatcgccc tgagttttga tgcgcaatca accaaaacct taaaaaatcg ttgggccgat
    20821 ctggggattg agctcttata tcaagaaagg ataggacatg acgacaaatc gtaaggacga
    20881 gcatatcctc tatgcccttg agcagaaaag ttcctataat agctttgatg aggtggagct
    20941 gattcattct tccttgcctc tttacaatct ggatgaaatc gatctttcga cagagtttgc
    21001 tggtcgaaag tgggactttc ctttttatat caatgccatg actggtggaa gtaataaggg
    21061 aagagaaatc aatcaaaagc tggctcaggt ggcggaatcc tgtggtattt tatttgtaac
    21121 gggttcttat agcgcagccc tcaaaaatcc aacggataat tctttttctg tcaagtctag
    21181 tcatcccaat ctcctccttg gaaccaatat tggattggac aaacctgtcg agttaggact
    21241 tcagactgta gaagagatga atcctgttct attgcaagtg catgtcaatg tcatgcagga
    21301 attactcatg cccgagggag aaaggaagtt tagaagctgg caatcgcatc tagcagatta
    21361 tagcaagcaa attcccgttc ctattgtcct caaggaagtg ggctttggaa tggatgccaa
    21421 gacaatcgaa agagcctatg aattcggtgt tcgtacagtg gacctatcgg gtcgtggtgg
    21481 caccagcttt gcctatatag aaaaccgtcg tagtggccag cgtgattacc tcaatcaatg
    21541 gggtcagtct accatgcagg cccttctcaa tgcccaagaa tggaaagata aggtcgaact
    21601 cttggttagt ggaggggttc ggaatccgct ggatatgatt aagtgcttgg tttttggtgc
    21661 taagtctgtg ggattgtcac gaaccgttct ggaattggtt gaaacctaca cagttgaaga
    21721 agtgattggc attgtccaag gctggaaagc agacctacgc ttgattatgt gttcccttaa
    21781 ctgtgccacc atagcagatc tacaaaaagt agactatctt ctttatggaa aattaaaaga
    21841 agcaaatgat cagatgaaaa aggcgtaacc agcgcctttt ttccatcctc agactgaggt
    21901 gacttttttg aattgtgata aaatagaagg gagaggatga acctatgaga aaatttaaaa
    21961 tctttttatt tatcgaagcc tgtcttctga caggagctct gattttgatg gtatcagagc
    22021 atttttcgcg ttttctgctg atactattcc tctttttgct tttgattcgc tactacactg
    22081 gtaaagaggg gaataatctt cttttagtag cggcaaccat tctcttcttt ttcattgtta
    22141 tgctcaatcc ttttgtgatt ctagctattt ttgttgcggt tatctatagt ctctttcttc
    22201 tttacccgat gatgaaccag gaaaaagagc agaccaattt ggtttttgaa gaggttgtga
    22261 cggttaagaa ggagaaaaat cgttggtttg gaaatcttca tcatttttca agctaccaga
    22321 cttgccaatt tgatgatatc aatctctttc gcttcatggg caaggacact attcatctgg
    22381 agagagtcat cttaaccaat catgacaatg tcattatcct cagaaagatg gtaggaacga
    22441 ccaaaatcat cgtacctgta gatgtggaag tcagtctcag cgttaactgt ctctatgggg
    22501 atttgacttt tttcaaccag cccaagcgag ccctccgcaa tgaacactat catcaagaaa
    22561 caaaagacta tctcaagagt aacaagagtg tcaagatttt cttgaccact atgattggtg
    22621 atgttgaggt ggttagagga tgaaaaaaca agcctatgtc attatcgctc tcacctcctt
    22681 cctgtttgtc ttttttttct cccatagctt gctggaaata cttgattttg actggtctat
    22741 ctttttgcac gatgtcgaaa aaacagaaaa atttttcttt ttattgttgg ttttcagcat
    22801 gtccatgacc tgtctcttag ccctgttttg gcgagggatc gaagagcttt ctctaagaaa
    22861 aatgcaggct aatctcaagc gtttattggc agggcaagaa gtggttcagg ttgtagatcc
    22921 agatttggat gccagtttca agtccttatc aggtaaactt aaccttttga cagaggctct
    22981 tcaaaaagct gaaaatcata gccttgctca ggaagaggaa atcatcgaga aggaacggaa
    23041 gcgaattgct cgggatttgc acgatacagt cagtcaggag ttgtttgcgg cccacatgat
    23101 tttatcgggt atcagtcagc aggctttgaa attggataga gaaaagatgc agacccagtt
    23161 gcagagtgtc acagctattt tagaaacagc ccagaaggat ttgcgggttt tgctcttgca
    23221 tttgcgacca gttgaactgg agcagaagag cttgatagaa gggattcaaa ttcttttaaa
    23281 agagcttgag gacaagagtg atcttagggt tagtctcaag cagaatatga cgaaattgcc
    23341 taagaaaatc gaggagcata tcttccgtat cctgcaagag ttgattagca ataccctccg
    23401 ccatgcccag gcatcttgcc tagatgtcta cctctatcag acagatgttg aattgcaact
    23461 gaaggtggtg gacaatggga ttggtttcca gttagggagc ttagacgact tgagttatgg
    23521 actgcgaaat atcaaggagc gggttgaaga tatggctgga acagttcaac tcttgacagc
    23581 tcccaagcaa gggctggcgg ttgatatccg tattcctctg ttagataagg aatgataaag
    23641 gagtaaagat gaaaatttta ctagtagatg accatgaaat ggtccgattg ggcttgaaaa
    23701 gctactttga cctccaagac gatgtagaag ttgtgggtga ggcgtccaac gggtctcaag
    23761 ggattgactt ggccttggaa ctgcgtccag atgtcattgt catggatatt gtcatgcctg
    23821 agatgaatgg gattgacgcg accttagcaa tccttaaaga atggcctgaa gccaagattt
    23881 tgattgtgac ctcttatttg gacaatgaaa aaatcatgcc agtcttagat gctggtgcca
    23941 aaggctatat gctcaagact tctagtgcag atgaattgct tcatgccgtc agtaaggtag
    24001 ctgctggcga gctggccatt gagcaagagg ttagcaagaa ggttgaatac caccgcaatc
    24061 atatggaact tcatgaagaa ttgactgcgc gtgagcgaga tgttctccaa ctcatcgcca
    24121 agggctacga aaatcagcgc atcgcagatg acctctttat ctctctcaag acggtcaaga
    24181 cccacgtgtc caatattctt gccaaacttg aagtcagcga tcgtacccag gcggctgtct
    24241 atgcctttca gcaccatttg gtggggcaag aggagtttta gatgagttta gcagatttac
    24301 ttgaggagct agaagcagca aaagactcta aaaaagcaag gtccatggaa gcctatatgc
    24361 gccatcaatt ttcttttcta ggtattgcgg tgcctgaaag aaataaactc tataaaatat
    24421 tttccagaag cgaaaaaaac aaagattatc gattgggatt ttgcagacac ttgctgggaa
    24481 aagaatccta gaaaatacca atatgtggct gctaactatt tgaaagcaat gcagtcttat
    24541 ctaaaggaaa ccgatttgcc taagctagag cagttagtcg tgacaaaatc ctggtgggac
    24601 acggtagata tcctagatcg agtagtaggg agtttggtgt atgaacactc tgaactagaa
    24661 gaaataatct taatactctt cgaaaatctc ttcaaaccac gtcagctcta tctgcaacct
    24721 caaaacagtg ttttgagcaa tctgcggcta gcttcctagt ttgctctttg attttcattg
    24781 agtataaaat ggagcctatc agataatatc tggctgagac gtgtcgctat tgaccaccag
    24841 ttgttaagaa aagagaagac caatactcaa ttaatggaaa agattctact tcataacttg
    24901 aaccaaacag aattttttat caataaagcc attggctgga ctctgcgaga ctactccaaa
    24961 acgaatccca cttgggtaac atgctttatt gagaaaaaca aggaaagaat ggctgaactt
    25021 agtatcaaag aagcaagcaa gtacctctag cgtgattgaa aagcgcagtc attaattgaa
    25081 aagtttacct gtttatgtga taatggaggg tatttaaaga aggtggtaga tttcttgatt
    25141 ctatagtaga ttaagaaatt tagaatagta cgctataatt acattaggag gatacaataa
    25201 tgaagaaaac tgtttataaa aaattgggta tttcaattat tgcgagtact ttattggcta
    25261 gccagttatc gacagtatct gctttgagtg ttatttctag tacaggtgaa gaatatgagg
    25321 taagtgagac actagaaaaa ggtccagagt ctaatgattc ttcattatct gagatttcac
    25381 caacgtatgg ttcatactac caaaagcaat cagaagtatt atcggtaatg atgatttgat
    25441 taaaattgat aatactttac agtatccgta ttcgacttca gctatggttt tatctaagta
    25501 ttatggagta gccgatggaa tgaatgtaga agggagggga agtgcgaatt ttattaaaga
    25561 taatgtgtta attacagcgg ctcacaacta ctacagacat gactatggga aagaagcgga
    25621 tgatatttat gttcttccgg ctgttagtcc aagtcaagaa ctatttggaa agatcaaagt
    25681 aaaggaagtt cgttatttga aggaatttag aaatttaaat tctaaggatg caagggaata
    25741 tgacttggct ttattaattc tagaagagcc cattggtgca aaattaggga ctttgggtct
    25801 tcctactagt caaaaaaatt tgacaggaat aactgtgact atcacaggct atccatcata
    25861 taattttaaa attcatcaaa tgtatacaga taaaaaacaa gttttaagtg atgatggcat
    25921 gttcttggat taccaagttg atactttaga ggggtctagt ggatctacag tttatgatgc
    25981 tagtcaccgt gtagtaggag tgcatacttt aggagatgga gctaatcaaa ttaacagtgc
    26041 agttaaatta aatgaacgaa atttgccatt tatttattcg gttcttaaag gttactctct
    26101 tgaaggatgg aagaaaataa atggtagttg gtaccattat agacaacatg ataaacaaac
    26161 gggttggcag gagataaatg atacttggta ttatttagac agttccggta agatgcttac
    26221 agattggcaa aaagtaaatg gaaaatggta ttatctcaat tcaaatggag caatggttac
    26281 aggtagccaa actatcgatg gtaaagttta taacttcgct tcatctggtg agtggattta
    26341 atgttggagg atatataaaa tgaatctttt gaaaaaaatg atgcaaatcg cactagccac
    26401 atttttcttc ggtttgttag cgacaaatac agtatttgca gatgattctg aaggatggca
    26461 gtttgtccaa gaaaatggta gaacctacta caaaaagggg gatctaaaag aaacctactg
    26521 gagagtgata gatgggaagt actattattt tgatccttta tccggagaga tggttgtcgg
    26581 ctggcaatat atacctgctc cacacaaggg ggttacgatt ggtccttctc caagaataga
    26641 gattgctctt agaccagatt ggttttattt tggtcaagat ggtgtattac aagaatttgt
    26701 tggcaagcaa gttttagaag caaaaactgc tacgaatacc aacaaacatc atggggaaga
    26761 atatgatagc caagcagaga aacgagtcta ttattttgaa gatcagcgta gttatcatac
    26821 tttaaaaact ggttggattt atgaagaggg tcattggtat tatttacaga aggatggtgg
    26881 ctttgattcg cgcatcaaca gattgacggt tggagagcta gcacgtggtt gggttaagga
    26941 ttaccctctt acgtatgatg aagagaagct aaaagcagct ccatggtact atctaaatcc
    27001 agcaactggc attatgcaaa caggttggca atatctaggt aatagatggt actacctcca
    27061 ttcgtcagga gctatggcaa ctggctggta taaggaaggc tcaacttggt actatctaga
    27121 tgctgaaaat ggtgatatga gaactggctg gcaaaacctt gggaacaaat ggtactatct
    27181 ccgttcatca ggagctatgg caactggttg gtatcaggaa agttcgactt ggtactatct
    27241 aaatgcaagt aatggagata tgaaaacagg ctggttccaa gtcaatggta actggtacta
    27301 tgcctatgat tcaggtgctt tagctattaa taccacagta ggtggttact atttaaacta
    27361 taatggtgaa tgggttaagt aatgaagact aattgtaaac tgtgatggat acttaacttt
    27421 gtataatagg tggataaaag tcttcacaat caaaaaacgc atagtatcaa ggtttttctg
    27481 tactgccccc caaaagttag acaaataatt tatccgaagg atttagttct gtattgcaca
    27541 gggctaagtc cttttagttt taccttaatt cgtttattgt tgtagtaatc aatatagtct
    27601 acaatagctt gttccaattg attaagtgat ttaaatgttt tctcatagcc ataaaacatt
    27661 tccgatttca gaatcccaaa gaaggactcc atcataccgt tgtcttggct gtttcccttg
    27721 cgtgacatgg atgcttgaat tcccttaccc tcaagaaact gatgataaga atcgtgttga
    27781 tattgccagc cttggtcact atggagaatc gtattctcgt agtgcttctc tgtgaatgcc
    27841 tgttccaaca ttgtttgtac ttgttctaag ttgggtgaag ttgaaagatt ataggcgata
    27901 atttcgctat taaagccatc t
//
LOCUS       DBEJKC010000026        23918 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.026, whole genome shotgun sequence.
ACCESSION   DBEJKC010000026 DBEJKC010000000
VERSION     DBEJKC010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 23918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23918
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.026"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(125..529)
                     /locus_tag="ACL3G6_001147"
     CDS             complement(125..529)
                     /locus_tag="ACL3G6_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HGR0545688.1"
                     /translation="MKTFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQIIAYIGAVLCLIIMLLLMWGLKYYKK"
     gene            complement(526..690)
                     /locus_tag="ACL3G6_001148"
     CDS             complement(526..690)
                     /locus_tag="ACL3G6_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545689.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            complement(987..1106)
                     /locus_tag="ACL3G6_001149"
     CDS             complement(987..1106)
                     /locus_tag="ACL3G6_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGR0545690.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKDTDSTP"
     gene            complement(1109..1267)
                     /locus_tag="ACL3G6_001150"
     CDS             complement(1109..1267)
                     /locus_tag="ACL3G6_001150"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545691.1"
                     /translation="MQLGDFAKAGVGGAAARGLQLGIKTGTWQGAATGAAGGAILGGV
                     AYAATCWW"
     gene            complement(1204..1338)
                     /locus_tag="ACL3G6_001151"
     CDS             complement(1204..1338)
                     /locus_tag="ACL3G6_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin class II family protein"
                     /protein_id="HGR0545692.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWEILPKQVLEEQQQEVFN
                     "
     gene            complement(1407..1676)
                     /gene="blpJ"
                     /locus_tag="ACL3G6_001152"
     CDS             complement(1407..1676)
                     /gene="blpJ"
                     /locus_tag="ACL3G6_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HGR0545693.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGSGLTCLGGMVGDKLGLSW"
     gene            complement(2142..2339)
                     /gene="blpI"
                     /locus_tag="ACL3G6_001153"
     CDS             complement(2142..2339)
                     /gene="blpI"
                     /locus_tag="ACL3G6_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HGR0545694.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            2620..4773
                     /gene="blpA"
                     /locus_tag="ACL3G6_001154"
     CDS             2620..4773
                     /gene="blpA"
                     /locus_tag="ACL3G6_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HGR0545695.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLVIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            4784..6145
                     /locus_tag="ACL3G6_001155"
     CDS             4784..6145
                     /locus_tag="ACL3G6_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HGR0545696.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSIISSIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTSNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPIITDTREVLITYYVASDYLPLLDKGQTVRLKLEKIGNHGITIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            6202..6357
                     /gene="blpC"
                     /locus_tag="ACL3G6_001156"
     CDS             6202..6357
                     /gene="blpC"
                     /locus_tag="ACL3G6_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HGR0545697.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDILYSLNIIKHNNTKG
                     LHHPIQL"
     gene            complement(6402..7742)
                     /locus_tag="ACL3G6_001157"
     CDS             complement(6402..7742)
                     /locus_tag="ACL3G6_001157"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0545698.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGIGLTFERIFKAFLLKILL
                     AFVFVMIGYMVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQEQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKD
                     KLHDRLDQEQVLRYRDIERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDLVLRDSSQKLQDNKYDLGRLVNVRDRALKSLLAGKFIKAREKDIVFNVEVPEEI
                     QVEGMRLLDFLTIVSILCDNAIEASAEAGQPHVSIAFLKSGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIPTE"
     gene            complement(7756..8493)
                     /locus_tag="ACL3G6_001158"
     CDS             complement(7756..8493)
                     /locus_tag="ACL3G6_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0545699.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(8498..8836)
                     /locus_tag="ACL3G6_001159"
     CDS             complement(8498..8836)
                     /locus_tag="ACL3G6_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR0545700.1"
                     /translation="MKHMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEKASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            9112..9441
                     /locus_tag="ACL3G6_001160"
     CDS             9112..9441
                     /locus_tag="ACL3G6_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGR0545701.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(9609..10658)
                     /locus_tag="ACL3G6_001161"
     CDS             complement(9609..10658)
                     /locus_tag="ACL3G6_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0545702.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(10655..11386)
                     /locus_tag="ACL3G6_001162"
     CDS             complement(10655..11386)
                     /locus_tag="ACL3G6_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0545703.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            11454..11864
                     /locus_tag="ACL3G6_001163"
     CDS             11454..11864
                     /locus_tag="ACL3G6_001163"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGR0545704.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMNATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            11874..12161
                     /locus_tag="ACL3G6_001164"
     CDS             11874..12161
                     /locus_tag="ACL3G6_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545705.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(12527..13663)
                     /gene="dnaJ"
                     /locus_tag="ACL3G6_001165"
     CDS             complement(12527..13663)
                     /gene="dnaJ"
                     /locus_tag="ACL3G6_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HGR0545706.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(13868..14221)
                     /locus_tag="ACL3G6_001166"
     CDS             complement(13868..14221)
                     /locus_tag="ACL3G6_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545707.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDYTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(14234..16057)
                     /gene="dnaK"
                     /locus_tag="ACL3G6_001167"
     CDS             complement(14234..16057)
                     /gene="dnaK"
                     /locus_tag="ACL3G6_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HGR0545708.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(16537..17061)
                     /gene="grpE"
                     /locus_tag="ACL3G6_001168"
     CDS             complement(16537..17061)
                     /gene="grpE"
                     /locus_tag="ACL3G6_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HGR0545709.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(17088..18122)
                     /gene="hrcA"
                     /locus_tag="ACL3G6_001169"
     CDS             complement(17088..18122)
                     /gene="hrcA"
                     /locus_tag="ACL3G6_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HGR0545710.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRIADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(18286..18795)
                     /locus_tag="ACL3G6_001170"
     CDS             complement(18286..18795)
                     /locus_tag="ACL3G6_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HGR0545711.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            19402..21735
                     /gene="hsdR"
                     /locus_tag="ACL3G6_001171"
     CDS             19402..21735
                     /gene="hsdR"
                     /locus_tag="ACL3G6_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EcoAI/FtnUII family type I restriction enzme
                     subunit R"
                     /protein_id="HGR0545712.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAMVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVDKEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            21748..23211
                     /locus_tag="ACL3G6_001172"
     CDS             21748..23211
                     /locus_tag="ACL3G6_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGR0545713.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTNDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            23211..>23918
                     /locus_tag="ACL3G6_001173"
     CDS             23211..>23918
                     /locus_tag="ACL3G6_001173"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0545714.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQ
                     NKPEKSFRYIDTSSIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLK
                     NIAVVRELKEYLIASTAFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDY
                     NFNLLLIALPPLSEQQRI"
BASE COUNT         7675 a         4846 c         4274 g         7123 t
ORIGIN      
        1 tagaggcgta ctattctagt ttcaatctac tatactatac catattttgt ttcgcaggga
       61 atctattata aaagggtaag tattgcaaaa acacttaccc ttttctttta tacttcatta
      121 agctctactt tttataatac ttcaagcccc acatgagcag aagcatgatg attaagcaga
      181 gaacagcgcc aatataagcg attatttgtt ggtaggattc tcctgctgtg atacctctat
      241 acaaacaaat aatagacata aaacctgtca agccgatgaa cataagttga ttggttctag
      301 gactaaccaa atcatcatct tcaaactctc ttatcctcat ttccctagtg agataaacag
      361 taaccaaaat agaagccaag ttaataacta ctaaaagaaa ttggaaaact acggaaaaat
      421 ttaaaaactg acgagataga aatagataag tagaaacaag caagggcaac tgacctaaga
      481 acaatctcgc aaggaagatg ttccgttttt tagcaagaaa agttttcatt tcttttctcc
      541 tttcttttta ttgatagcaa aatagatcat aactgcaatc acataggcta tggtataaaa
      601 tagctgatac caagcactct ccctaagcgg atatagaaag atggacatga ttagatacag
      661 aacgaaaata atcagtattt ttttcttcat aagatttcct cctaaatgtg cgatttatct
      721 tagttgagca agaacattta cactgctagt atagcactta ttttgacctt ggatcactca
      781 aatcataaat ggtcatcaaa acctcttgaa ttgtaaaaat taaaaaagca agcatgaaaa
      841 acatactttc ctctttatat tgtattgata ccaacttgtt tgtagacttt tcatcctgct
      901 atcacatatc attttgacag gcgaaacaaa attaaagaaa ctcccctgta aattaagcta
      961 gcaaatacag gggagaaatt tattttttag ggggtactat ctgtatcctt tttgggaaat
     1021 tttgaaaata tttttctaat taaattatcc atataaggac caaatatacc aactactaaa
     1081 ccaataataa aacttttaaa atccataatt accaccaaca tgttgctgca taggctacac
     1141 ctccaagtat agctccaccc gcagcaccag ttgctgcacc ttgccatgtt cctgttttaa
     1201 tgcctagttg aagacctctt gctgctgctc ctccaacacc tgctttggca aaatctccca
     1261 attgcatccg ccaccttcaa cgcaagcaag catttcagta tccataacag aaaattgtga
     1321 catcattttt gtatccatga caaatactcc ttttttaaaa aactaaaata aatcagaata
     1381 gaatcctcat aattttacta taagtcttac caacttagtc ccaatttatc accaaccata
     1441 cctcctaagc atgttaatcc actcccaatt gcaccaatgt gtgctccaac aaatgcacca
     1501 gcaagtccag ctactcctaa agtggccaaa cctgctccag ttccaccagt tataattccc
     1561 gtagtgactc ctgtaatcag tgcattttga caatcagtgg agctataccc cccttcaact
     1621 ttcgcaagca tttcagtatc cataacctct aactgtgaca acatttttgt attcatgatg
     1681 aatacctcct ttttattttc aatttgttac caaagtctta aattcaataa acaaatagat
     1741 tttttatagt atctttttga ttttcttaaa aaagtatata cgtctactat cttcttaaag
     1801 gtagcagtac ctatttttag tctaagattt caataatctt gagtatctaa aatatcttaa
     1861 tttcgttatt ctccttgcaa taaaaagttt tactatacta tttattaact tgcagaaagc
     1921 aaaaaatatt agtaaataat agtttatagt taagtttttt attcctacca atccatcaac
     1981 taagtaaagc atcaacgatt acataaacga ttgataatat aattaaaatt ttgctaacta
     2041 tcttattctc atcattctta gataactttg atattttgta agtaagtaaa taagacagta
     2101 aattaatagc gataataata ctatatttaa gaatcataat cttacaaaga ggacataatt
     2161 cctgaaccta cacaaataag tgttgctgct cccccagtta tcggaccagt cgcagcagct
     2221 aatagtactg ctccaataca accaccgatt gcagatccta aattgcctct tcctccacta
     2281 actatttcga gttcttcatt atccataaca gaaaattgtt ccatcatttt tgtattcatg
     2341 acaaatactc cttttttatt tttaattttt gtcttgttgc aactttgaca agtttagtat
     2401 atcattattt tttaattttt ttcatccaaa tcttgaattg ccatcgaaac gtcttgaatt
     2461 agctttttta tttcaagcca cctctaaatg tttaaaaaaa ataatttcta atcacttttt
     2521 taccattcag gaagttttaa tgactattca acatttcata aaatatgaac ttagttttat
     2581 ggcataatat acctatccac tatatgaaag gaattgccaa tgacttctta taaacgtaca
     2641 tttgttcctc aaatagatgc gagagactgt ggtgtcgctg ccttagcctc gattgctaaa
     2701 ttctatggtt cagatttttc tctagctcac ttgagagaac ttgcaaagac caataaagaa
     2761 gggacgactg ctcttggcat tgtaaaagcc gctgatgaaa tgggctttga aacaaggcct
     2821 gttcaagcag ataaaactct ctttgacatg agtgatgtcc cctatccatt tatcgttcac
     2881 gttaacaaag aaggaaaact ccaacattac tatgttgtct atcaaacaaa gaaagactat
     2941 ctggttattg gtgatcctga cccttctgta aaaatcacta aaatgtcaaa agaacgcttt
     3001 ttctctgaat ggactggagt agctattttt ctagctccca aacccagcta tcaaccccat
     3061 aaagataaaa agaatggtct actaagcttc cttcctctga ttttcaaaca aaaatctctc
     3121 attgcttaca ttgttctctc aagcttattg gtcactatta tcaatatagg tggttcttat
     3181 tatctccaag gaatcttaga tgaatacatc ccaaatcaga tgaaatcaac tttaggaatc
     3241 atctcagttg gtctggttat cacctatatc ctccaacaag tcatgagctt ctccagagat
     3301 tatctcctaa ccgttctgag ccagagatta agcattgatg tgattttatc ctatattcgc
     3361 catatttttg aacttcccat gtctttcttt gcgacacgtc gtacaggaga aatcatttca
     3421 cggttcacag atgctaactc tattatagat gccttggctt ctaccattct ttctcttttc
     3481 ctggatgttt ctattctgat tcttgtaggg ggcgtcttac tggcacaaaa ccctaatctc
     3541 ttccttcttt ctcttatttc tattcctata tacatgttca tcatcttttc ttttatgaag
     3601 cctttcgaaa aaatgaacca tgatgtcatg caaagtaatt ctatggttag ctctgccatt
     3661 atcgaagata tcaacgggat tgaaactata aagtcgctca cgagtgaaga aaatcgctat
     3721 caaaatatag acagcgaatt tgtagattat ttggaaaaat cctttaagct cagtaaatat
     3781 tctattttac aaacaagttt aaagcaggga acaaaattag ttctgaatat ccttatccta
     3841 tggtttggcg ctcaattagt catgtcgagt aaaatttcta tcggtcagct gattaccttt
     3901 aacacacttt tttcttactt tacaactcct atggaaaata ttatcaacct ccaaaccaaa
     3961 ctccaatctg cgaaggtcgc taataaccgt ttgaacgaag tctatctagt cgaatctgaa
     4021 tttcaagttc aagaaaaccc tgttcattca cattttttga tgggcgatat tgaatttgat
     4081 gacctttctt ataagtatgg ttttggacga gataccttaa cagatattaa tctcacgatt
     4141 aaacaaggag ataaggttag cctagttgga gttagtggtt ctggtaaaac aactttagcc
     4201 aaaatgattg tcaatttctt tgaaccctac aaagggcata tttccatcaa tcatcaggat
     4261 attaaaaaca ttgataaaaa agtcttgcgc cgtcatatta attacctacc ccaacaagcc
     4321 tatatcttta atggctctat tttggaaaac ttaaccttgg gcggtaatca tatgattagt
     4381 caagaagata ttctaaaagc ttgtgaagta gctgaaatcc gtcaagacat tgaaagaatg
     4441 cctatgggct atcaaactca gctctctgat ggagctggtc tatcaggagg acagaagcaa
     4501 cgaatcgctc tcgctcgtgc tcttttaact aaatctcctg ttttaatact agatgaagct
     4561 actagcggtc ttgatgtctt gactgagaaa aaagttatag ataatcttat gtccctaact
     4621 gataaaacca ttctctttgt agcccatcgt ctcagtatag ccgaacgaac caaccgtgtc
     4681 attgttcttg accaggggaa aatcattgaa gttggtagcc accaagagtt aatgcaggcg
     4741 caaggtttct accatcatct attcaataaa taaggagaat gtcatgaatc ctaatctttt
     4801 tagaagcgtc gagttttatc agagacgtta ccataactat gcgacagtgt taattatacc
     4861 tctttcatta ctatttactt tcatcttgat tttctccctt gttgccacaa aagaaattac
     4921 tgtcacttcc caaggagaaa tcgcccctac aagtatcatt tcatctattc agtcaaccag
     4981 tgataatcct atccttgcta atcatttagt ggcaaatcaa gtagttgaaa aaggggactt
     5041 actcatcaaa tactctgaaa caatggaaga aagtcagaaa actgccttag caactcaatt
     5101 acaaagactt gagaagcaaa aagaaggact tggaattttg aaacaaagct tagaaaaagc
     5161 gactgatctt ttttctggcg aggatgaatt tggctaccat aataccttta tgaattttac
     5221 taaacaatcc catgatattg aactgggtat cacaaagact aacactgagg tttcaaatca
     5281 agctaatctt gccaatagca gttcatcagc tattgaacaa gaaattacaa aagttcaaca
     5341 acaaattgga gaatatcaag agctgagaga tgctatcata aataacagag cacgcttacc
     5401 aactagcaat ccacaccagt caattttgaa tcgttatctt gtagcctcac aaggacaaac
     5461 acaaggaacg gcagaggagc catttttatc tcaaattaat caaagtattg caggtcttga
     5521 atcatctatc gcaagcctca aaattcagca agctggtatc ggaagtgtag caacttatga
     5581 taatagttta gcaaccaaaa ttgaagtact ccgcactcaa tttttacaaa cagcttctca
     5641 gcaacaacta accgtggaga accaattaac agaattaaaa gtacaactag atcaagcgac
     5701 acagcgctta gaaaacaata ccttaaccgc tccaagtaaa ggtatcgttc atctgaacag
     5761 cgaatttgaa ggtaaaaata gaattccaac tggtacagaa attgctcaaa tattccctat
     5821 catcacagat acaagagaag tactaatcac ttactacgta gcttctgact atctacctct
     5881 actagataaa ggacaaactg taagattaaa actggagaag attggaaatc acggcattac
     5941 catcatcggc caacttcaga caattgatca aactcctacc agaacagagc aaggcaatct
     6001 ctttaaatta accgctcttg caaaactatc taatgaggat agtaaactca tccaatatgg
     6061 cttacaaggt cgcgtcacta gtgtaactgc aaagaaaaca tattttgatt atttcaaaga
     6121 taaaatttta acccattctg attaattttc agataacact ctataactat ttattatctt
     6181 atcaaaaagg agaatcataa catggataag aaacaaaact taacttcatt tcaagaacta
     6241 acaactaccg aactcaacca aattacaggt ggaggactgt gggaagatat cttatacagc
     6301 cttaatataa ttaagcataa caatacgaaa ggacttcatc atccaataca actataaaaa
     6361 ataagaccga gtaacaagaa ctctcggtct tatttttttc atcattctgt aggtatcata
     6421 gtaagcacct gacgaaagac ttgatcttga caggtagtat ttaaactggc attgggataa
     6481 ctttccacaa tcttcataac ggtatagaga ccgacacctc tctcctcccc tttagaacta
     6541 actccaaagg agaagatttc agaaatatcg atgccctctt ctttgatgga gttttcaatg
     6601 ataaaagtct cctgtgctcc actttttaaa aaggcaattg aaacatgagg ttgaccggcc
     6661 tctgcactcg cttcaatagc attatcacaa aggatagaca caatggttag aaaatcaagc
     6721 agtctcatcc cctcaacctg aatctcttca ggaacttcga cattaaagac aatgtccttt
     6781 tctctagctt ttataaattt tccagctagg agacttttga gggcacgatc ccgaacattc
     6841 accaatctgc ccaggtcata tttattgtcc tgcaatttct gactggaatc ccttaagacc
     6901 aagtcataga cctcttttat ctgctccata tcctcctctt caatacccag acgtaaactt
     6961 gtcaagaggt tggtgtagtc atggcgaaaa ctccttactt ccttgtaaag ttcctctata
     7021 tgccgactat agcgttctat atctctatag cgcaagacct gctcttggtc cagtctatca
     7081 tggagtttgt ccttcaaata ggtatccaat ttcttgataa cccccataaa aaataggagg
     7141 taaaacacta gaatgagatg gcgaacagtc gttgattgaa taccttgctc atattcaaag
     7201 taagacagac tttgtatcac caaatagtaa gcccccatta tccagttaat cttagtcagg
     7261 gacttttgaa aacctgtatc tagaatctcc cttctcaaac tagtaaaatc atagtccaac
     7321 catttcaaaa aggctagaga aatgaagaaa ttgaaaatta ttatacataa cccagtaaat
     7381 gagtagccat catatacttg ctcttgtccc aaaaatggaa gcacaaaata ggagactcct
     7441 ctataaaaga gattcaccaa tatcattgga aagagaccat aaaagaaaag gagtttttta
     7501 ggaagccctc ttaacaataa gaaagacaag cctatgccgt acaagggttc cataaaataa
     7561 gataggtaaa catttcctac catatagcca atcattacaa aaacaaaggc caacagtatc
     7621 ttcaaaagaa aggccttaaa aatcctctca aaagtgagac caattccatc taccttaaag
     7681 aaaatgacaa tttttaatcc gtgagtaaca agtgtataca acaatatcca agcaacattc
     7741 ataaactctc ctagctcagt gtaagttatt aatagcctca gacacttccc tgaccttata
     7801 acgcgcgatc agacagcttc caccattggg aaagaaaagg agtttttctt tcttatccaa
     7861 atgcaccaca tttgcaggat tgatgagaaa agagcgatgg cactgcaaga gacggggttc
     7921 ctgcttaaaa acctcctcta aactcgccgt aaattctagc ctgtccgtct tggtatagag
     7981 aataacacga tggggtcttg gggatgtttc gagatagtaa acctctttga aaggatattg
     8041 gaattgggca aattttgatt taaagtaaaa gcaatcttcc gccagacttt tactatcttg
     8101 actattggca tagaggaggg ctgtctcgat acgagattca aactcctctg ccgaaagggc
     8161 cttatcaatg tagtccaaag ctgacacttg gtagcgaaag gacagaggca taaactccga
     8221 gtgagtcgtc acaaagacga ttagggcata agggtcttgt tcccgaatct ttctagctac
     8281 ttccagtccc ttcatctctt catttcgaat ctcaatatcc aaaaagaata gctgatgggc
     8341 ccccttctca tgcacctctg ccagcagttg gtccggcttg ccaaatacct caaaagagct
     8401 aggaatgata tgatgtgctt tcaaaagttt ctcaatcgtc gtttcaattc tagtctgttg
     8461 ggaaaaatca tcttctaaaa caaatattct catcttctta ctctccctct ttcaaccatt
     8521 tttgacgtat ttctctatag cgacgtctgg catacttgac agcatattga ccttcttctc
     8581 cgagaaaaag gattctttct tgaaaatcaa tcgattttaa tttatcaaga ttaaccaaac
     8641 aatttcgatg acatctcatc aaagtttccc cacattggtt ctcaagatta cttaaatttt
     8701 gaagcatatt aaaactagct ttttctgtaa caatctgtac ggtatgggct ttagttggat
     8761 gtgtttggat atagtagata tcgtcgatgt ttactttata gactgttttc tgtgtctgaa
     8821 taatcatatg tttcattgga ttctcctcct aagaaaagaa taacagaaaa ggtctagccc
     8881 aagcacaccc aatcctaaac agtctttgaa aactcctaaa aggattattt tctacaacat
     8941 catgatgagc ttacaactat tttatcataa aattcactca gcgcaattca agacatttca
     9001 atgacaatta aagatttgaa taaaaaaaaa gaattaaaag tgataaacta acagtatcaa
     9061 aacacagttg ccagaagtaa gactggcacc cagattaaag gaggcattcc catgacagat
     9121 acagacccca tcaaaagagc tcatactttg attactgact taaacaaagc ctaccaagca
     9181 tgcaaacagg caagcgctga cgacgtccgc tttcaggagc aattaaactc tattcttggt
     9241 tttctagcca aggctgaaac agtggataat cgattcttga ttgaactaga aaaattttac
     9301 cagacttcca gtcttctcat gggactcagc gctcttgatc cagatgctcc aactcgcgcc
     9361 gcttggcggg cctatgaccg cttccacttt gaccaagtca agaccaagtt aatactcaat
     9421 gagaatcaaa gagcaaacta ggaagctagc cgcaagctgt acttgagtac ggtaaggcga
     9481 cgctgacgtg gtttgaagag attttcgaag agtataagtc tctacggacc aaccattatc
     9541 ctgtagtaac aaaaaagaag ctgagacaga ctgaactcaa cttctttttt agtgtcgtat
     9601 cagcaatgtt agtcctgcat ctgacgtttt acctgataag gcaaatacaa gactagtaaa
     9661 accaaaccag ctcctagtaa ggctagaagg gccagttttt cttggaaggt aatcaaccca
     9721 acaactaatt ccacaagtaa aacaaaactg gtcaatcctc gaactacctc ctgtaagcct
     9781 ttttcctttt gccccttgtc cagcggaaag agttgggtca aatactggta gtcaaaggca
     9841 tgatagaggg ccagcaactg gaagagcaag aggtagttaa agagaactac cactgctgtc
     9901 gcaatccaag cttgctcgat aaaaacctgc gccagtacgg aaagtaatag aagacgaaga
     9961 ctgagagcaa agaggtcgcc atttcgcaga taagaacgca gatagagatt ttgccaaatc
    10021 ttcccaggca ccttctgaac agcctttaag ataaagtcca gataggcacg acgcttaacg
    10081 ctgtttgaaa ttcccttgac ctgcgtaaag agggcaaaga aacgaagcaa gacttgctta
    10141 cgcttgcttt cttgagaaat aacatagtcc cagtccagtc cagtttcagt gaaaaatttg
    10201 ctggcctttt gacgaaagtg gaaatatttt cctaccccca ataaaagcac atagagcaga
    10261 aaaactggca agccataacc cattgctaaa aataaaggcg caaataacag caagaaaagg
    10321 gtctgtacaa agagccaaaa gactagggaa atgccagttt gacgcttgag atggagcttg
    10381 atttcctctt ctccaactaa gagaaagagc ttgtctggag cctccatata ggtggcaatt
    10441 cctccccaaa gtaaaagtaa aacagacgta attcctacaa acaaaaggat aggccaatga
    10501 ttttcaggaa aatgttgtaa gagttgactg tactggtagg ctagaaagcc caacaggaca
    10561 agcaggaaca agacaaagtg gtcattgagc acatagcgca gataaccaag acactcctta
    10621 cgaaaggcct gctttctctt taaaaacaag tctttcatag gtcctcctct tttgtcagag
    10681 ccaagtaaat atcattcaaa ctagcctcag gcatatcaaa ggcttcgcgt agttgcagga
    10741 gattgccttt ggcacgcacc tctcccttgt gaagaatgac aaaggcatca cacatcttct
    10801 ccgccgaatc cagcacgtgg gtactcatga gaatagactt gcccttttgc ttctccactt
    10861 ccaaaagctg aatcaaatca gaaatagcca gcggatcaag accaaggaaa ggctcatcca
    10921 cgatgaaaag acttggatcc accacaaaag cacagataat catgaccttc tgcttcatcc
    10981 cttttgaaaa atgaacaggg aaccagtcta atttctgttc caaacggaac atttttaaca
    11041 agggctctac tcgttcgaaa gccacttttt gctcaatacc gtaagccata gcaaccgttt
    11101 cgatatgctc tctgagggtc aattcctcat acagactagg cgtctcagga atgtagccaa
    11161 tctgcttgcg gtagctagtc gcatctcctt gcagagtcag gccattgata ttgatggagc
    11221 cactataagg tgccaacaga ccgataatct cattgatcgt cgttgatttc ccagcaccat
    11281 tgagaccaat caaaccgacc aactgcccac tttcaacagt aaaggacaca tctttcaaaa
    11341 caggaacatg aacatagcca cctgtcaggt ttttaatttc taacatattt tctccaaatc
    11401 tggtataatg tagctatatt atatcaaaat tcagtacagt agaggtagat tttatgtcag
    11461 attgcatttt ttgtaaaatc atcgcagggg aaattcctgc ttcaaaagta tatgaagatg
    11521 agcaggtcct tgcctttctt gatatctctc aagtaacact aggacacacc ttggtcgtgc
    11581 caaaagaaca ctatcgcaat cttttggaga tgaatgctac gagcgccagc caactctttg
    11641 cccaagtacc aaaagtagct caaaaagtca tgaaagtcac taaggctgct ggtatgaata
    11701 tcatttccaa ctgtgaagaa gtcgctggtc aaacagtttt tcatactcac gttcaccttg
    11761 tgcctcgcta cagtgctgac gatgacctca agattgattt tatcgcccac gaaccagact
    11821 ttgacaaact tgctcaagtc gctgaaacca tcaaaaacgc ttaaggagtt gctatgaaat
    11881 tatccaacct actgctattt gcaggagctg cagccggaag ttatctggtt acaaaaaatc
    11941 gccaaaccat cacagatgaa gtcttaaata ccactgaccg cgttcaagct atcaaagacg
    12001 atgtggatat tatccaaaat agcctgcaaa tcatcgacca gcaaaaagaa cttatcaagg
    12061 aataccaaga agacttgact tacaagttta aggtcttgga aaaggatatc cagactagac
    12121 tagctgtgat aaaagaaatg cagggaactg aagataagta aaaagagccc ccggctcttt
    12181 tttaaaacgt aaacaagtta tagtgaattg aatttagaat agcacatcat agtttctaaa
    12241 gcattgttag agattacttt aaaatcctct tatcaatttg ttcatattct atttcaatct
    12301 actatatata tcccatcaac tatgcatcat aatttaggta actcatactc aataaaaatc
    12361 aaaaagcaaa ctagaaagct aggcacagac tgctcaaaac accgttttaa ggttgtggat
    12421 agaactgacg aagtcagctc aaaacactgt tttgaggttg tagatacgac tcacatatat
    12481 acggcaagcc gacgctgacg tggtttgaag agattttcga agagtattat tctccatcaa
    12541 aggcatcttt aatatggtca aagaagcctt ttttctttgg atttactttc aagtcaccag
    12601 cagccgcgaa ttctttcaag gctacttttt ggcggtcgtt caagcctgtc ggtgttacga
    12661 cattaacagt aacgtattgg tcaccaactg caccgccacg aaggctcggt gcccccttac
    12721 tacgtaggcg gaatttctta ccagtctgag ttccctctgg aataaccaat tcaacatcac
    12781 cgtgaacagt tggaatatct actgtatcac caagagccgc ttggacaaag ttgaggttga
    12841 gattgtagaa gatagtcgtt ccttcacgtt caaacttgtc gctagcttct acagaaacta
    12901 ctacatacaa gtcaccataa ggtccaccgt taaagcctgc ttcaccttga ccagcgaggc
    12961 gaatttgttg acctgtttcc acaccagcag ggattttcac atgtacgcta tgagcttgtt
    13021 tctcatgacc tgttccatga caggttgtac atggatattt gatttctttt cctcgaccgt
    13081 gacagacatc acaggttact tggcgacgca tcataccaag aggagtctgc gtatcgacgt
    13141 taatgacacc agcgccatga cagcgtccac aagtgactgg acttgtccct ggcttagcac
    13201 cagagccatt acatgtacga cagccagctt cacgatgata cttaacttcc ttctcagttc
    13261 cgaagatagc ttcttcaaag gtcaaattga cacgatactg gagatcatct ccttggcgag
    13321 gagcgtttgg attgcgcgaa gaaccgcctc cgccgaagaa acttgagaaa atatcctcaa
    13381 aaccaccgaa gccacctgcc ccattgaaac cgccgaaacc accagctcca ccaaaaccac
    13441 cattggcgcc tgcagcacca tactggtcat aggcagcacg tttttggtcg tcactcaaag
    13501 tctcataggc ttcttgaact tccttgtact tgtcctcagc accaggctcc ttgttgatat
    13561 ctgggtgata ttttttggaa agcttacgat aagccttttt gatctcgtct gccgaagcgt
    13621 tttttgacac ccccagacga tcataaaatt cagtattgtt catacaagat accaagaccg
    13681 taaaattcga ctgaaaaata ggaaatctga cgctggagcg acgctcctag acagatttct
    13741 cttttttccg agaatttagg tcgggttcaa ttcctttctt ttatattgat gagataatac
    13801 tccagccact cggccctatc cctttttacc gaaaaacaga ggctgggttg caacctctgt
    13861 ggttagatta ttcatttgaa ataaaaatgg ttgtattatc tctagtagta atcttcaaag
    13921 accttttagc taaatcaaac tcaaatttat tatagtgtgg gtcttgtgtt ttatataggt
    13981 gtaactcctg acatatatga tccgaaaagt aaatcataac atctttaaac acagaagtgt
    14041 agtcatattt actcttacca acagctactt ctgtaaattc tttataaatg acatttccat
    14101 ttctttccac agtcaccagc atttctgttg gattataatc caaattaaat aattcttcaa
    14161 aaaactttat cttttcatga taatctgcaa tgtcagaaag attattttta ttaacactca
    14221 taacactagc cccttacttt tccgtaaact ctccgtctac gacgtcatcg cctgcgtttc
    14281 ctgttgcttg tgcgccttct gctccttctt gagcttgttg cgctgctgcg gcttgttcgt
    14341 agagtttaac agcaagtcct tgagcttttt cgttcaatgc ttcaagtttt gctttcatgt
    14401 cgtccaagtt gttgtcttct tgagctttct taaggtcatc aagggcagct tgggcagcgt
    14461 cacgttctgc gtcgaagcct ttaccttcag tttccttgat tgtcttttca gtcgcaaaga
    14521 ttgcttggtc tacttcatta cgaaggtcta cttcttcttt acgtttctta tcggcttcag
    14581 cgtttgcttc tgcatctttc atcatgcggt cgatttcttc gtcagtcaaa cctgagttcg
    14641 attggatgac aatagtttgt tctttttgag ttccaaggtc tttggcctta acagacacga
    14701 taccgttctt gtcgatatca aatgttactt cgatttgagg aattccacga ggtgcagctg
    14761 ggatatcagt caattggaag cgtccaagag tcttgttatc tgctgccatt gggcgttcac
    14821 cttgaagaac gtggatatca acggctggtt ggttgtctgc tgctgttgag aagacttgtg
    14881 atttagatgt tgggattgta gtgttgcgat cgataagttt tgtaaatact ccacccattg
    14941 tttcgatacc aagtgacaat ggcgttacat caagaaggac aacatccttg acatcaccag
    15001 taatcacacc accttggata gccgcaccca tagcaactac ttcatcaggg tttactgatt
    15061 tgtttggttc tttaccagtt tcagctttaa cagcttcaac aacggcaggg atacgagttg
    15121 aaccaccaac aaggataact tcgtcgattt ctgacaagct caaacctgca tctgaaaggg
    15181 cttgacgaac tggaactttt gtacgttcaa caaggtcacg agtcaaatca tcaaatttcg
    15241 cacgagttaa agtcatttcc aagtgaagag gtccagcctc acctgcagtg ataaatggca
    15301 agctgatttg tgttgaagtt acaccagaaa ggtctttctt cgctttttca gccgcatctt
    15361 tcaaacgttg cattgccatc ttgtcagtag acaagtcgat accgttttct ttcttgaatt
    15421 ctgctaccaa gtggtcaatg attttttggt caaagtcgtc accaccaagt ttgttgtccc
    15481 ctgcagttga caatacgtcg aagacaccgt cacccaattc aaggatagag acgtcgaatg
    15541 taccaccacc aaggtcaaat accaagattt tttcttcttt gtcagtcttg tccaaaccat
    15601 aagcaagagc tgctgcagtt ggttcgttaa caatacgttc tacttcaaga ccagcaattt
    15661 taccagcgtc ttttgttgct tgacgttgag cgtcgttgaa gtaagccgga actgtgataa
    15721 cagctttggt tactttctca ccaaggtagt cttcagcgta gcctttcaag tattgaagga
    15781 tcatagctga gatttcttgt ggagtgtatt cttttccatt tgcagaaact ttttcagaag
    15841 ttcccatctt agatttgata gagataactg tatctgggtt tgtgactgct tgacgttttg
    15901 cagcatcacc aacgatgatt tctccgtttt tgaatgagac tacagatgga gttgtgcggt
    15961 ttccttctgg gtttgcgatg attttgcttt cagttccttc aagaactgca actgctgagt
    16021 ttgttgtacc taagtcaata ccgataattt tagacatgtg tttttctcct tgttagttaa
    16081 ttttctattt ttctttttga tactcttctt aagtggcgac gccgtcagag cttgacttcg
    16141 tcaatctctt tgactaaact ttgagcctaa ggtctcaaaa tttgcgcaaa tagcgccacg
    16201 gcgaagagta tcgtgtttgg ttcgcttcgc tcactattac aaagccaaac atattttatc
    16261 tttcttcata gtttattgtc gtttcggaca agttttctat tatgtaaatt gcgacacgaa
    16321 gagtcgaaat cgattttatt tcgacgacga gttagtaagg aagctaggca aacgccatag
    16381 cgattgccgt tttctgacga gttgctttag ctaccgtcag aattgccgaa tcgaacacgc
    16441 cctaagctct gagtaaaaaa gatagatttt cttgtgttca tcgaacactt cgtcaatctc
    16501 ctatttttac tgcgagcttt ttacgggctt tgtatcttag ttatacacca ctaccattgc
    16561 tgggcgtagg atgcggtcat ggagtttgta gcctttttga aagacttgag cgatggtatc
    16621 tactgggtgt tcatcgtctg ctgggagagt ttggatggcc atatggtagt tatggtcaaa
    16681 ttcgccatct gctgcgattt cttcaattcc ttcttctttc aaagcgtgaa tcaagctttc
    16741 ttgcaccatc cccaagccct tcttcacatc atctgtcaaa ccttcaactg caagtgcacg
    16801 ctcaaggttg tcaagagatg gtaagattgc ttttgccaag tcctggctac gataacgttg
    16861 caagttttga cgttcttcat tggcacggcg ttggatattt tgcatttctg catgagcgcg
    16921 aagatatttg ttttcgaact catctgcacg ttcatttgcc aagtccaact cagacttttc
    16981 aggagttgtt tcttcagctg tttccacaac ttcctcttct tgaacttctt ctacttcttc
    17041 attttttata tcttgggcca tgttcgcctc ctttaatgat ttcaatctta atgtacttcg
    17101 taatgattac tgctgaggta gcggtaaaaa tctgtcaact tcatggtcaa aacacggttg
    17161 accacattga tttgattgat tagctgttgg taatccagat taactggacc gataatggct
    17221 agaattccaa ctccccgata aggaatgagg aacttactac taatcaccgc taggtcagct
    17281 aaacaggact cttgaccgtc tgcaatacga acattttgca tctgatcctc acgcaacccc
    17341 tcacgaatct ccaaggccac cttttgcggt tggtcaaaga actgataggc tgctagattg
    17401 gcaaaattca agagattgac cttgcccgcc atcacaatgt tttcgttgaa catttcctta
    17461 aagatgtgtt caaagagatc gatgacatta tccgttgttg taaagtaacg ctggataatc
    17521 tgcggaatct ccgtccgaat cttgtagtga atatctaaaa cggtgtgacc gaggaaacgt
    17581 tcctgaatga tgctcttcag tttcagcaaa tcctcctgca agaagttcct tggaatcaga
    17641 aactgactag taaccgttcg cgactcgtct agggtaaata ccgccaaggc tgtatgttgc
    17701 cccaaaacaa cgatatcaaa ggctgtcaaa cgttgcctgc tcggctcaac atccagtgcc
    17761 actaccgtac agccactcag gtctgttagc aagttagcag cctcttgcag aatatcctcc
    17821 aatttgaaga attcctgatc aaaggctttg acaatctcat atacctcatt ttcagccagc
    17881 cggtgaaaat ccagtgagtg tttcacatag tactgaaaac cagcaacact tggcatccga
    17941 ccgcttgaag tatgagcctt ctcaagcaac ccttgttttt ctagttccgc catgtcatta
    18001 cgaatggttg cactgctaga gttaatagac tcttgcaagg cttttgatcc gacaggttcg
    18061 tgcgttttgg taaagatgtc aataatcaga tttaaaatat cctgctgacg ctctgtaacc
    18121 atctcatcac tcctctctgt ctgatcaatt agcactcaat gcatccaagt gctaacttat
    18181 gattctatta tacaccctta gaagagaatg tcaagacaaa aactcaaaaa attagcactc
    18241 ttttatcaag agtgctaaaa atcaatctga agacctagaa ccttgctatt catctactcg
    18301 gtatttcctt tttagtctga aataaccatg aattagataa gaaatcagaa aagcatataa
    18361 aacaaaaata agaaagaaag acatagaaag atcctctcta aacaaactcg tacaaacaac
    18421 aagaccacct aagaaagtag ttgtacagga acgaagtcta gatcgcataa cttcccattt
    18481 gagcccctta ctcatataga cttgatcctc tggaagtaaa tcagaagacg atttacgaag
    18541 aatcgaacaa gaacctgctc ctatcaattc ccaacctcta tctctaaaat cttgcagttc
    18601 atgcttatat tttttaagaa atctagaatc atagatacgg tagatgacat cgtctggttg
    18661 acattggtca aaatagaaca aaccaaaacg actcgttcta tacctccaac ctttcaaatg
    18721 catctcatgt aaatattctt cttccttgtc caaatcaaca atagtgaaaa tccgaaattc
    18781 tactctgcta ttcattgtct taccccaaaa ttagaaaaca tgcctggcgt tatttattag
    18841 ataattcttt ccgcttttga ctcaatctcc aaaaaatata agaaatctga atcgcaaaaa
    18901 ctatcaataa aacccaatct attatgaaag tcaaaaacac ttcccaactg aaagaactac
    18961 ctccagtgac aaactttgag aaaaacggta gtagagctaa aaagagaagc aaaataggaa
    19021 gcatccgcat tgttaaaatc cttttggcat aaaaaaatct ttatttaaac gaaaatatta
    19081 tggcaaaatt tacgccagtt tttgaacggc tgatgtagat attttatact ttcaaaatgt
    19141 ttaaatgtga ttatttattt ttgaaaaata gctcaccagc ccgactgaaa gtgcttataa
    19201 atgataataa gtcgcctgcc gaaaacagcg aaaaatagcg gtgttatgcg gagataatct
    19261 gacgcgatgc gaaagtatat tgcatactta ttttcaacaa tttagcagag tatttttata
    19321 agtgtgatat aatagaagta taatttgttc tgatagttta ttttatggag aagtagattt
    19381 ttagaatgcg gagggttcaa tatggttgag tttataaagt ctaagaaaga aatgagtgag
    19441 gaggatatta aagcaaattt catcactcct gctattgtat ccaaaggatg gaaaaatggt
    19501 gagcatatcg cttacgaaga atacttcact gatggtcgaa ttgaggttag aggagataag
    19561 gctcgtcgta aagaaggaaa aaaatcagac tattcactgt attaccaatt tggaactcga
    19621 attgcaattg ttgaggcaaa ggataataaa cacagcgttc gagcaggatt acaacaagct
    19681 attgaatatg gagagatttt agatgttcca tttgtttatt cttcgaatgg tgatggcttt
    19741 attgaacacg accgtatcac gagagaagaa cgtgagctgg agttagacga attccctact
    19801 cgtgaagaat tattttctcg tatgacgaag gaaaaaggat tgacgtacga aattacagaa
    19861 gctatctcaa ctccatacta tacagacgcc ttctcaatga aaacgccacg ctattatcag
    19921 caaatagcta tcaaccgtac tattgaaaca gttgccagag gacaaaaacg agtaatgttt
    19981 gtgatggcaa caggaacggg gaaaacgttc atggcttttc aaattattca tcgccttcga
    20041 aaagctggtt tggctaaacg agttttattc ttagcggata gaaacatctt agtagaccaa
    20101 acgatggctg aagactttag gccattcgaa aaggtaatga cgaaaattac accaaaactt
    20161 ttgactgctc ctgaaaaatt aaattctttt gaaatttatc tagggcttta tcagcaacta
    20221 actggtgaag atggaactga aacacattat caaaaatttg acaaagactt ctttgattta
    20281 atcgtaattg atgaagcgca ccgtggttca gctaaggaaa acagtaactg gcgtaagata
    20341 attgattatt tcagttctgc gacacagatt gggatgaccg ctactcctaa agaaaccaag
    20401 aatgcttcca atacggaata ctttggtgag ccaatctata cttatagttt aaaacaggga
    20461 atcgaggatg gttttttggc tccatatcgt gttatgaggg ttaatttaga tgtggatgtg
    20521 gatggttatc gtccagaaac tggaaaagtt gatgctaacg gacaattaat agaagatagg
    20581 tactacggca ggaaagattt tgataaaacc attgtcattg atgatagaac gcaaagagtt
    20641 gccaagtttg tttctgatta tatgaagcaa aacaatgcac gatttgataa aacaattgtt
    20701 ttttgtgttg atattgacca tgccgagcga atgcgtgctg cacttgtaaa agagaatcta
    20761 gacttagtcc aagaagacta tcgttatgtc atgcaagtaa ctggtgacaa cgctgaagga
    20821 aaagctcaac tggataactt tatggatgtc aattctaatt ttcccgctat ggtaacaacg
    20881 tctaaattat taacgacagg agttaatgct aaaacatgtc gtttgattgt tttagactct
    20941 aatatccaat ccatgactga atttaaacaa attattggtc gtggcacacg tctttatcct
    21001 caaaagggga aagaattttt tacgattatt gattttcgaa atgttaccaa tttgtttgct
    21061 gaccctgatt ttgatggtga tcctgtgaag gtgctggaaa caggtgcgaa aacagtcagt
    21121 ggttctacgc ccggtttcgt agataaggaa ggtgacccag tagaaaaata tatcgttaca
    21181 gacaagcagg ttaccattct taattctact gttcaagtat tggatgaaaa cgggaaactg
    21241 attaccgaaa gcctgaccga ctacactcgg aagaatatct taggtagcta cgccactttg
    21301 aacgatttta tcacagtttg gcatacggcg gataaaaaga agcttatctt agacgaactt
    21361 tataaaaaag gagtttatct agatgctatt cgagagtcgg agggaatatc agaacaagaa
    21421 atcgatgatt ttgatttact cctaaaactt gcctatggtc aaaaagaatt aaccaaaacg
    21481 gaacgtatca ataaactcaa acaaagcgga tatttatata aatatagtga ggaagcgcgt
    21541 gctgttttgg aaattttact gaacaaatac atggataaag gtattggaga actcgaaagc
    21601 attgaaacat taaaacttcc agaatttcag atatatggtg gaaccttcaa aatcatcaat
    21661 acttattttg gagataaaaa acgatattta caagcaatta aagaattgga gcaagagcta
    21721 tttacagtag cttaatgaaa ggaaagtatg tcaattacat catttgtaaa aagaattcaa
    21781 gatatcactc gaaacgatgc tggtgttaat ggtgatgctc aacgtattga gcaaatgtct
    21841 tggttattat tcttaaaaat ttatgatagc cgtgaaatgg tttgggaatt agaagaagac
    21901 gagtatgagt caattatccc agaggaatta aaatggcgaa attgggctca tgctcaaaat
    21961 ggggaacggg tattgacagg cgatgaatta cttgattttg tcaataacaa gttattcaaa
    22021 gagttgaaag agcttgaaat aacttcaaat atgcctattc gaaaaacgat tgttaaatca
    22081 gcttttgaag atgcgaacaa ctatatgaaa aatggcgtct tgttacgcca agtcatcaat
    22141 gttattgatg aagttgattt caatagccct gaagatcgtc attcgtttaa tgatatttac
    22201 gaaaaaattc ttaaagatat tcaaaatgct gggaactcag gagaatttta tacgccacgt
    22261 gcagcgactg attttattgc cgaagttctt gacccaaaac ttggagaatc aatggcagac
    22321 cttgcttgcg gaacaggagg cttcttgact tcgactctga accgtttaag tagtcaacgt
    22381 aaaactagtg aagataccaa aaaatataat acagctgttt ttggtattga aaagaaagca
    22441 tttcctcatc ttttagcagt tacaaatctg tttcttcacg aaattgatga ccctaaaatt
    22501 gttcatggaa atactttgga gaaaaatgtt cgtgaatata cgaatgatga aaaatttgac
    22561 attattatga tgaatccacc ttttggaggg tcagaattag aaacaataaa aaataacttt
    22621 ccagcagaat tacggagttc tgaaacagct gatttattta tggctgtcat tatgtatcgt
    22681 ttgaaagaaa atggtcgtgt tggagttatt ttacctgatg gttttctatt tggtgaaggt
    22741 gtaaaaactc gcttgaaaca aaaactggta gatgagttca acttgcatac gattattagg
    22801 ttgcctcata gtgtctttgc accgtataca ggaatccata cgaacattct tttctttgat
    22861 aaaacaaaga aaacagaaga aacttggttt tatcgtttag atatgccaga tggttataaa
    22921 aatttctcga aaactaagcc gatgaagtca gaacacttca atcctgttcg tgactggtgg
    22981 gaaaatcgtg aagagattct ggaaggtaag ttctacaaat ctaaatcatt tacacctagt
    23041 gaattggctg agttgaatta taatttagac cagtgtggtt ttccaaaaga ggaagaggaa
    23101 atcttaaatc cctttgagtt gattcagaat tatcaagcgg aaagagcaac tttaaatcat
    23161 aagattgata atgtattagc tgatattttg cagttgttgg aggacaaata atgacaccag
    23221 aacaacttaa agcaagtatt ctccaaagag cgatggaagg gaaattagtg ccgcaaaatc
    23281 ccaatgacga acctgcaagt gaattattaa agagaattaa agctgaaaaa gaaaaactta
    23341 tcagtgaagg aaaaatcaaa cgagataaaa aggaaactga gatatttcgt ggtgatgatg
    23401 ggaaacatta tgggaagttt gctgatggaa gcactcaaga aattgatgtt ccttatgata
    23461 ttcctgatac ttgggagtgg gtgaggataa aatcaattta ttggaatttt gggcaaaata
    23521 agccagagaa atcctttagg tatatagata cgtctagtat tgatagaaaa aagaacataa
    23581 tcaactacaa aaatctacaa tatctttcac ctgaacaagc gccttcccgt gctagaaaat
    23641 tagtttcgca gaatagtgtc ttattttcaa cagttagacc atatctaaaa aatattgctg
    23701 tagttagaga acttaaagag tatttgatag ctagtacagc atttattgtt ttggatactt
    23761 tacttaacga aacatatttg aaatattatt tattatcaga taattttatc aatcgtgtta
    23821 ataataaatc tactggaaca agttatcctg caatcaatga ttataatttt aatctattat
    23881 taattgctct ccccccacta tccgaacaac aacgaata
//
LOCUS       DBEJKC010000027        23381 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.027, whole genome shotgun sequence.
ACCESSION   DBEJKC010000027 DBEJKC010000000
VERSION     DBEJKC010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 23381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23381
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.027"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..867
                     /locus_tag="ACL3G6_001174"
     CDS             <1..867
                     /locus_tag="ACL3G6_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence associated protein"
                     /protein_id="HGR0545715.1"
                     /translation="KRKNSLYFKDFNSKIDQIDNTLIAIENYIASMYATELETDSLAE
                     NTFGYFLGNEEEKEKIKELFILIKSKIITSSVETEIIAKNSIGLYQSELLKEWVQENK
                     TSILSCEKEEELLGVLTKKIIDFSNNKEMRKLSIENLNYISQLWIKGISYFQILESCT
                     EKSISIEKRGKSKPIDMSDIISICDNGLGYETSMVLNAINNILEKLVGEELDVLTMLI
                     KRLKYGLPLEKEINIYELGFSDRIVVQVIGQEINSVSKNQIRNEIKQKSARLEDKLSD
                     FPSYYTQIINEM"
     gene            892..1788
                     /locus_tag="ACL3G6_001175"
     CDS             892..1788
                     /locus_tag="ACL3G6_001175"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HGR0545716.1"
                     /translation="MTKISFEIQQQIIQCFGLCFHYKDTVVSFMQTSGVPNDLILKWK
                     SEPKFVWAKNVINELNKTENGRLIIRRIATEFYKMKNIPDEVQDRDRGLDALRKLKRL
                     IGDTQQNKVNETLNNSYHRSRQEMKIQLRQQLLQKIEELKTEYYSLFSSDNPQERGYR
                     LEKIVANLFRINDIDYHDSYRNRTNTQQLDGYFRFEGFDYLVEMKWEKNPVNSPKIAS
                     LKQKVDTKLTSTRGLFLSINGFRDEVIQDFSNKDAKILFMDGQELAYILENRISLYEA
                     LKVKIIGASKTGNPNVSIINQE"
     gene            2120..2429
                     /locus_tag="ACL3G6_001176"
                     /pseudo
     CDS             2120..2429
                     /locus_tag="ACL3G6_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            2573..3802
                     /locus_tag="ACL3G6_001177"
     CDS             2573..3802
                     /locus_tag="ACL3G6_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGR0545717.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGITIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            3822..6518
                     /gene="ppc"
                     /locus_tag="ACL3G6_001178"
     CDS             3822..6518
                     /gene="ppc"
                     /locus_tag="ACL3G6_001178"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HGR0545718.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    6601..6818
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6931..7935
                     /gene="trpX"
                     /locus_tag="ACL3G6_001179"
     CDS             6931..7935
                     /gene="trpX"
                     /locus_tag="ACL3G6_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0545719.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTIKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            8004..8870
                     /locus_tag="ACL3G6_001180"
     CDS             8004..8870
                     /locus_tag="ACL3G6_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0545720.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            8867..9625
                     /locus_tag="ACL3G6_001181"
     CDS             8867..9625
                     /locus_tag="ACL3G6_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0545721.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            9715..11475
                     /gene="dnaG"
                     /locus_tag="ACL3G6_001182"
     CDS             9715..11475
                     /gene="dnaG"
                     /locus_tag="ACL3G6_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HGR0545722.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            11478..12587
                     /gene="rpoD"
                     /locus_tag="ACL3G6_001183"
     CDS             11478..12587
                     /gene="rpoD"
                     /locus_tag="ACL3G6_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HGR0545723.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            12601..12930
                     /locus_tag="ACL3G6_001184"
     CDS             12601..12930
                     /locus_tag="ACL3G6_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGR0545724.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            13045..14088
                     /gene="cpoA"
                     /locus_tag="ACL3G6_001185"
     CDS             13045..14088
                     /gene="cpoA"
                     /locus_tag="ACL3G6_001185"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HGR0545725.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            14104..15429
                     /locus_tag="ACL3G6_001186"
     CDS             14104..15429
                     /locus_tag="ACL3G6_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR0545726.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGILIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGALYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFRTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            15460..15636
                     /locus_tag="ACL3G6_001187"
     CDS             15460..15636
                     /locus_tag="ACL3G6_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGR0545727.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            15695..15829
                     /locus_tag="ACL3G6_001188"
     CDS             15695..15829
                     /locus_tag="ACL3G6_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HGR0545728.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            15893..17203
                     /gene="obgE"
                     /locus_tag="ACL3G6_001189"
     CDS             15893..17203
                     /gene="obgE"
                     /locus_tag="ACL3G6_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HGR0545729.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            17213..17371
                     /locus_tag="ACL3G6_001190"
     CDS             17213..17371
                     /locus_tag="ACL3G6_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545730.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(18153..18278)
                     /locus_tag="ACL3G6_001191"
     CDS             complement(18153..18278)
                     /locus_tag="ACL3G6_001191"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545731.1"
                     /translation="MKIKDQTRKLAAGCSKHCFEVVDGTDVVSILHIRQGDIDVI"
     gene            18421..19680
                     /locus_tag="ACL3G6_001192"
     CDS             18421..19680
                     /locus_tag="ACL3G6_001192"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGR0545732.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            19696..20247
                     /locus_tag="ACL3G6_001193"
     CDS             19696..20247
                     /locus_tag="ACL3G6_001193"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0545733.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            20240..21517
                     /gene="spxR"
                     /locus_tag="ACL3G6_001194"
     CDS             20240..21517
                     /gene="spxR"
                     /locus_tag="ACL3G6_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS-HotDog domain-containing transcription
                     factor SpxR"
                     /protein_id="HGR0545734.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIDRLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            21533..22393
                     /locus_tag="ACL3G6_001195"
     CDS             21533..22393
                     /locus_tag="ACL3G6_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HGR0545735.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            22773..23381
                     /locus_tag="ACL3G6_001196"
                     /pseudo
     CDS             22773..23381
                     /locus_tag="ACL3G6_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT         7341 a         3914 c         5157 g         6969 t
ORIGIN      
        1 aaaagaaaga acagtcttta ttttaaggat tttaattcta agatagacca gattgataat
       61 accctaattg caattgaaaa ttatattgct tctatgtatg ctactgaatt ggagactgat
      121 agtttagctg aaaatacatt tggatatttc ttaggtaatg aagaggaaaa agaaaaaata
      181 aaagaattat ttatcttgat aaaatctaaa ataattacca gttcagtaga aactgaaata
      241 attgcaaaaa actcaattgg attatatcaa tctgagttat taaaagaatg ggttcaggaa
      301 aataaaacat ctatcctttc ttgtgagaag gaagaagagt tattaggtgt tttaaccaag
      361 aaaataatag atttttcaaa taacaaagag atgagaaaac taagtataga aaatctaaat
      421 tatatttctc aactctggat taaggggatt tcttattttc aaatattgga aagttgtact
      481 gaaaaatcaa ttagtattga gaaaagaggt aagtcaaaac caattgatat gtctgacata
      541 atctctattt gtgataatgg attagggtat gaaacatcaa tggttttaaa tgcgattaat
      601 aatattcttg aaaaactagt tggagaggaa ttggacgtat tgactatgtt aataaagagg
      661 ctgaaatatg ggctacctct ggaaaaagaa atcaatatct atgaattagg tttttcagat
      721 agaattgtgg tccaagttat tggtcaagag attaattctg taagtaagaa tcaaattaga
      781 aatgaaatca aacagaaatc agctagacta gaagataaat tgagtgattt tccaagttat
      841 tatacacaga taattaatga aatgtaatat tgttgataaa aaggagaaaa aatgactaaa
      901 atatcttttg aaatccaaca acaaattatt caatgttttg gattatgttt tcactataaa
      961 gatactgtcg tttcatttat gcaaacttcg ggagttccaa atgatttaat attaaaatgg
     1021 aaatcggaac cgaagtttgt ttgggcgaaa aatgttataa atgaacttaa taaaacagaa
     1081 aatggaagat tgataattag acgaatagca actgaatttt ataagatgaa aaatattcct
     1141 gatgaagttc aagatagaga tagaggatta gatgcgttaa gaaaattaaa gcgactgata
     1201 ggtgatactc aacagaataa ggttaacgaa acacttaata attcttatca tcgttccaga
     1261 caggaaatga aaatacaact caggcaacaa ctccttcaaa aaattgaaga actaaagacg
     1321 gagtattatt cgctattttc aagtgataat cctcaagaaa gaggatatcg tttagaaaaa
     1381 attgttgcta atttattcag aattaatgat attgattacc atgattcgta tagaaataga
     1441 acaaatactc aacagttaga tggctatttt aggtttgaag gttttgatta tttagttgaa
     1501 atgaaatggg aaaaaaatcc agtaaattct ccgaaaatag cttctttaaa acaaaaagtt
     1561 gatacaaaac taacttcgac tcggggactg tttctttcaa taaatggttt tagagatgaa
     1621 gtaatacaag atttttctaa taaagatgct aaaattttat ttatggatgg acaagaatta
     1681 gcttatattc tagaaaatag aattagtttg tacgaagctt taaaagttaa gataattggt
     1741 gcttctaaaa ctggcaatcc aaatgtttct ataattaatc aagaataact tttccgagag
     1801 atattaaaac catcaataaa atagagcgat actttatatg ccatgataca aatgatatac
     1861 aatgatactt ctgaccgttc aggctgccat cgtaaaagag cagcaagtga aattcttatg
     1921 atgacttcat cagtcatgcc acgttaaatg tgtgagtttg ttagagaaac gcaattaatc
     1981 ctcaaaaggt tccccgaacc ttttgagttc cacagacgca tcacgtggag tgtgtaagct
     2041 tgttgctaaa agcgtaaaaa ccttggaacg aaaggaataa tagacttcct gcgaaacaaa
     2101 aatacaatac aataaaacta tggatgatga agcaagtaaa caattaagcg atagccgttt
     2161 caagagcctt gtaggtgttc agcgcacgag atgttagctg tgttaaaaac agcttatcaa
     2221 cgcaacgtaa acgcgcaaaa ggtggacgaa aaaccaaatt aagcctagac gatctcctca
     2281 tggtaactat tcaatacatg cgagaatagc acacttatga acaaattgcg gctgattttg
     2341 gcattcacga aagcaacata attagtcgga gtcaatggat tgaagcaact cttattcaaa
     2401 atggttttac gatttcaaat tctgccttaa ttctgtaaaa acagtaaaat tcgaaggatt
     2461 gtaaggtaag agtttttttc tttctgaaaa aatggtataa tagcaatcaa aactagaaaa
     2521 taaaacggaa tttggaacag atttgtctgt atcctagtag agtggtgata ctatgaagat
     2581 tagtaagagg cacttattaa attattccat cttgattccc tacttgcttt tatctatttt
     2641 gggcttgatt gtggtctatt cgaccaccag tgctatttta attgaagaag gcaagagcgc
     2701 cttgcagttg gttcgaaacc aaggaatctt ttggattgtt agtttgatac tgattgcctt
     2761 aatttataaa ttgagactag attttttgag aaatgagcga ctaatcattt tagttatatt
     2821 aatagaaatg cttttattgt tcttggctcg ttttattggt atttccgtaa acggggcata
     2881 cggttggatt tcggttgcag gaataactat tcagccagct gagtacttaa aaatcattat
     2941 tatttggtat ttagctcacc gattctccaa acagcaagaa gaaatagcta cttatgattt
     3001 tcaagttttg actcaaaatc aatggcttcc ccgtgctttt aatgattggc gattcgttct
     3061 cctagttctg attggaagtt tgggaatttt ccctgattta ggaaatgcga ctattttagt
     3121 cttggtttcc ttgattatgt atacagttag tggaatcgct tatcgctggt tttcaaccat
     3181 tctggcgctc gtatctgccg cttctgtctt tgtcttgacc actatcagcc taatcggtgt
     3241 tgagaccttt tcaaaaattc cagtatttgg ctatgtagcc aagcgcttta gtgccttttt
     3301 taatcctttt gccgatcgtg ctgatgcagg tcaccagtta gctaattctt attttgccat
     3361 ggtcaatggc ggttggtttg gtctaggtct tggaaactcg attgaaaaac gaggttattt
     3421 gccagaagct catacagact ttgtcttttc tatcgtgatt gaagaatttg gctttgttgg
     3481 tgccagtctt attttagctc tcttattttt catgattttg cggattatct tggtcggtat
     3541 ccgagcggag aatcctttca atgccatggt tgcactcggt gtcggaggga tgatgttggt
     3601 tcaggtattt gtcaatatcg gagggatttc gggcttgatt ccatctacag gagtaacctt
     3661 ccccttctta tcccagggtg gaaatagtct tctagtctta tcagtggcag tagcctttgt
     3721 cttaaatatt gatgccagtg aaaaacgcgc taaattgtac cgagaattgg aaaatcaacc
     3781 aatgaacctt ctgttgaagt aggataaaga aaggatagtt tatgtctctt caaaaattag
     3841 aaaattatag taataaaagt gttgtgcaag aagaagtctt gattctaaca gaattactgg
     3901 aagatattac taaaaatatg cttgccccag agacctttga aaaaataata cagttgaaag
     3961 aattatcaac gcaggaagat tatcaaggtc taaaccgtct agtgactagc ttatcaaatg
     4021 atgaaatggt ctatatttca cgctatttct ctatcttgcc tcttttgatt aatatttcag
     4081 aggatgtgga tttagcttat gaaatcaatc atcaaaataa tattgatcag gactatttag
     4141 gtaaattatc tacaacgatt aaattggtag cagaaaagga aaatgccgtt gagatcctag
     4201 aacacttgaa tgttgtccct gttttgacag cccatccaac acaagtgcaa cgcaaaagta
     4261 tgttggattt aacaaatcat attcatagtc ttttgcgtaa ataccgtgat gttaagttgg
     4321 ggttgattaa taaagataaa tggtacaatg atttgcgtcg ttacatcgaa attatcatgc
     4381 agacagacat gattcgtgag aaaaaattaa aagtgactaa cgaaatcacg aatgctatgg
     4441 aatattataa cagctccttt ttgaaagctg tacctcattt gacgacggag tataagcgct
     4501 tagcgcaagc gcatggtctg aatttaaaac aggctaaacc aatcaccatg ggtatgtgga
     4561 taggtggtga ccgtgatgga aatccatttg ttacagcaaa gaccttgaag cagtctgcac
     4621 tcactcagtg tgaagtcatc atgaactact atgataaaaa gatttaccaa ctttatcgtg
     4681 aattttctct ttcaactagc attgtcaacg tcagcaagca agtcagagaa atggctcgtc
     4741 aatccaagga taactcgatt taccgcgaaa aagagcttta ccgtcgtgcc ttgtttgata
     4801 ttcaatcaaa aattcaggca actaaaacct atctgattga ggatgaagaa gttgggactc
     4861 gttatgaaac cgccaatgat ttctacaagg atttgattgc cattcgagat tctctactag
     4921 aaaataaggg tgagtccttg atttcaggtg attttgtgga attattgcag gcagtagaga
     4981 tatttggttt ttacttagcg tcaattgata tgcgacaaga ctctagcgtc tatgaagcct
     5041 gtgtggcaga actcttgaaa tcagcaggaa ttcattctcg ttatagcgag ttgagcgaag
     5101 aagaaaagtg tgaccttctc ttgaaagaat tagaagaaga tccccgaatt ctttctgcga
     5161 ctcacgcaga aaaatcagaa ttattagcaa aagaattagc tatttttaag acggctcgtg
     5221 ttttgaaaga taagttggga gatgatgtca tccgtcagac catcatttca catgcaacca
     5281 gcctttctga tatgctagaa ttagctattc tgttaaaaga agtaggactg gtggatacgg
     5341 aaagggcgcg tgttcagatt gttccccttt ttgaaacaat tgaagacttg gatcattcag
     5401 aggaaacaat gagaaaatat ctttctctta gccttgccaa aaaatggatt gactcacgaa
     5461 ataactacca agaaatcatg cttggctact ctgacagtaa taaagatggc ggttacctgt
     5521 catcatgttg gaccctctac aaggctcaac aacaattgac tgctattgga gatgaatttg
     5581 gcgttaaggt taccttcttc catggtcgtg gtggtactgt cggtcgtggt ggtgggccaa
     5641 cctatgaagc cattacatct caaccgctca agtctatcaa ggatcgtatc cgcttgacgg
     5701 agcagggtga agtaattggg aataaatacg gtaacaaaga cgccgcttac tataaccttg
     5761 aaatgctagt atcggcagct attaaccgta tgattactca gaagaagagc gataccaata
     5821 ccccaaatcg ttatgaagcc attatggatc aagtagtgga ccgtagttac gatatctacc
     5881 gtgatttggt ctttggtaat gagcatttct atgattattt cttcgagtca agtccaatca
     5941 aggctatttc aagttttaat attggttctc gtccagccgc tcgtaagact attactgaaa
     6001 tcggtggttt gcgtgccatc ccttgggtat tctcatggtc acagagtcgt gttatgttcc
     6061 ctggatggta cggggttggt tcaagcttca aggaatttat caataaaaat ccagagaata
     6121 ttgctatctt acgagatatg taccaaaatt ggcctttctt ccaatcgctt ctttcaaatg
     6181 ttgatatggt tttgtcaaaa tcaaatatga atattgcttt tgaatatgct aaactttgtg
     6241 aagacgagca agttaaggcc atctatgaga ctattttaaa tgaatggcaa gttactaaga
     6301 acgttatctt ggctattgaa ggacatgacg aactcttagc tgacaatcca tatctaaaag
     6361 ctagtctgga ttaccgtatg ccttacttta atattctcaa ctatattcag ttagagttga
     6421 ttaaacgcca acgtcgtgga gaattgtcca gtgatcaaga acgattgatt catatcacca
     6481 tcaacggaat tgcgacagga ttgcgtaatt caggttgata attttcaaga gtgaatgcta
     6541 aaagtgaata tcaaaaaaat tctaatagac tattgacaag tagtttaaaa atgatataat
     6601 ttaaccattc agaaaagtaa tcatacaaac tttttagaga gtctgtggta gctgaaaaca
     6661 gataagtggc gatgatgaaa attgggctga atgctattta gaatttgaaa ttataaaaat
     6721 tcggtaagca caccttacag tgcatctcgt tattgcgaga ctgagcgata gggaaattcc
     6781 ctataattga ggtggtaccg cgcatcgacg tcctcacaca agttttttgt gtgaggattt
     6841 ttttgatgga ggttagtatg gaaagaaaac gatggcgtcg cttgtttaga taagtgaaat
     6901 atgttaaagg aaataaaaag gagaaacaga atgaaaaata aacgtttaat tggaattatt
     6961 gctgcattag cagtcttagt agcaggaagc ttgatttatt cttcaatgaa taaatcagaa
     7021 gctcagaata ataaggatga gaagaaaata accaagattg gtgtgcttca atttgtgagc
     7081 catccatccc ttgatttgat ttataaaggg atccaagatg gacttgcaga agaaggatat
     7141 aaagatgatc aagttaaaat tgattttatg aactcagaag gtgatcaaag taaggttgcg
     7201 acaatgagta aacaattggt tgcaaatggg aatgaccttg tggttggtat tgcaacacca
     7261 gcagcccaag ggttggctag tgcaacaaaa gacctaccag ttatcatggc cgctattaca
     7321 gacccaattg gtgctaactt ggttaaagat ttgaaaaaac caggtggtaa cgttacaggg
     7381 gtatctgacc acaatccagc tcaacaacaa attgaactca tcaaggctct gacaccgaat
     7441 gtgaaaacaa tcggagctct ttactcaagt agcgaagaca attcaaaaac acaggttgaa
     7501 gaatttaagg cttatgctga aaaagcaggt ctgacagtgg aaacatttgc agttccttca
     7561 acaaatgaaa ttgcctcaac tgtcactgtt atgactatca aggtagatgc tatttgggtt
     7621 ccaattgata acaccattgc atcaggattt ccaacggttg tctctagcaa tcaaagttct
     7681 aagaaaccaa tttatcccag tgcgacagct atggtagaag taggtggttt ggcatcagtt
     7741 gtaattgacc aacatgacct tggtgtggca acaggtaaaa tgattgtgca agtcttgaaa
     7801 ggtgcaaaac cagccgatac cccagtcaat gtcttttcaa ctggtaagtc agtcatcaat
     7861 aaaaaaatag cacaagaact aggtattact attcctgagt ctgttctcaa agaagcagga
     7921 caagtcatcg aataaataag gtagggagga ggagactctt cccatttttt aaaaagatga
     7981 atatagaaag gattaaataa aatatgattg tttccattat ttctcaagga tttgtctggg
     8041 ctattctagg tctgggaatc tttatgacat ttaggatttt aaactttcca gatatgacga
     8101 cagaaggttc cttccctctt gggggagctg ttgctgtcac tttgataacc aaaggcgtga
     8161 acccattttt agcgacactt gttgctgtag gagcaggttg tttggctgga atggcagcag
     8221 gccttcttta tacaaaaggg aagatcccaa ccttgctctc agggattttg gtgatgactt
     8281 cttgtcactc aatcatgctc ttgattatgg gacgtgcgaa tttaggcctg cttggaacca
     8341 agcaaattca ggatgttttg ccttttgatt cggatttgaa tcaactcttg acaggtctca
     8401 tctttgtgag cattgttatt gctctcatgc tctttttctt ggacactaaa ctcggacaag
     8461 cctatattgc tacaggggat aatcctgata tggctagaag tttcgggatt catactggac
     8521 gcatggagct catgggcttg gtcttatcaa atggtgtgat tgcccttgca ggtgccctca
     8581 ttgctcagca agaaggctat gccgatgtgt ctcgagggat cggggttatc gttgtggggc
     8641 ttgcaagttt gattattgga gaagttattt tcaagagttt gagcttggca gagcgtttgg
     8701 ttactatcgt tgtaggttct atcgcttatc aatttttagt gtgggcagtt atcgcacttg
     8761 gctttaatac aagttacctt cgtttataca gtgccttgat tttagcagtc tgcctcatga
     8821 ttccaacatt taagcaaaca atcttgaaag gagccaagtt aagcaaatga cagcaattgt
     8881 agaattaaaa aatgcaacca aaattgttaa aaatggcttt gatgaagaaa agattatttt
     8941 aaatgatgtt tccttagaaa tttttgaacg ggactttatc acgattttgg gcggaaatgg
     9001 tgctggaaaa tcaaccctct ttaacactat agcagggacc ttatcactaa ctagtggaac
     9061 tatccgtatt ttaggtgaag atctcactaa gttttcaccc gagaagcgtg ccaagtacct
     9121 gtctcgtgtc ttccaagatc caaagatggg gacagctccc cgtatgacgg tcgctgaaaa
     9181 tcttttaatc gccaagtttc gtggtgagaa gcgtggattg ttaccacgac gcttgactag
     9241 ctataaggat gaatttcagg caaccattga aaaagtagga aatggtcttg agaaacactt
     9301 gaatacaccg attgagttct tatcaggtgg acaaagacag gctttgagtc tcttgatggc
     9361 aaccttgaag cgacctgaat tactcctgtt agatgagcat actgctgccc tggatccaaa
     9421 gactagtgtt gctttgatgg aattgacaga tgaatttgtt aagaaagatc agctaacagc
     9481 ccttatgatt actcatcata tggaagatgc tctcaaatac ggcaatcgct tgattgtcat
     9541 gaaagaagga cggattatcc aagatttaaa ccaagaagaa aaagcaaaaa tgaaaatctc
     9601 tgattattat caactctttg aataaagtag ggaaaatgag tgaaatggtt tacttttttt
     9661 ctgaaataaa gtatactata taaagtaaac tatgataaca tggaggtatt gtgtatggtt
     9721 gacaaacaag tcattgaaga aatcaaaaac aatgccaaca ttgtggaagt cataggagat
     9781 gtgatttctt tacaaaaggc aggacggaac tatctagggc tctgtccttt tcatggtgaa
     9841 aaaacacctt ctttcaacgt tgtagaggac aagcagtttt accactgttt tggttgtggt
     9901 cgctcaggtg atgtctttaa attcatcgag gagtaccaag gggttccctt tatagaggct
     9961 gtccaaatct taggtcagcg tgtcgggatt gaggttgaaa aaccgcttta tagtgaacag
    10021 aagccagcct cgcctcacca agctctttat gatatgcacg aagatgcggc taaattttac
    10081 catgctattc tcatgacaac gactatgggc gaagaggcca gaaattacct ttatcagcgg
    10141 ggtttgacag atgaagtgct taaacatttt tggattggtt tagcacctcc agaacgaaac
    10201 tatctctatc aacgtttgtc tgatcagtat cgtgaagagg atttactgga ttcaggcctg
    10261 ttttatctct cggatgccaa tcaatttgta gacacctttc acaatcgcat tatgtttccc
    10321 ctgacaaatg accaaggaaa ggtcattgcc ttctcaggtc gtatctggca aaaaacggat
    10381 tcacaaactt ctaagtataa aaacagccga tcgactgcaa tttttaacaa aagttacgaa
    10441 ttatatcata tggatagggc aaaaaaatct tctggaaaaa ctagtgagat ttacctgatg
    10501 gaaggattca tggatgttat tgcagcctat cgggctggaa tcgaaaatgc tgtggcgtcg
    10561 atgggaacgg ccttgagtcg agagcatgtt gagcatctga aaaggttaac caagaaattg
    10621 gttcttgttt acgatggaga taaggctggg caagccgcga tattgaaagc attggatgaa
    10681 attggtgata tgcctgtgca aatcgttagc atgcctgata acttggatcc tgatgagtat
    10741 ctacaaaaaa atggtccaga agacttggcc tatctattaa caaaaactcg tattagtccg
    10801 attgagttct acattcatca gtacaaacct gaaaacagtg aaaatctgca ggctcagatt
    10861 gagtttattg aaaaaatagc tcccttgatt gttcaagaaa agtccatcgc tgctcaaaac
    10921 agctatattc atattttagc tgacagtctg gcgtcctttg attataccca gattgagcag
    10981 attgttaatg agagtcgtca ggtgcaaagg cagaatcgca tggaaagaat ttccagaccg
    11041 acgccaatca ccatgcctgt caccaagcag ttatcggcta ttatgagggc agaagcccat
    11101 ctactctatc ggatgatgga atcccctctt gttttgaacg attaccgttt gcgagaagac
    11161 tttgcatttg ctacacctga atttcaggtc ttatatgact tgcttggcca gtatggaaat
    11221 cttcctccag aagttttagc agagcagaca gaggaagttg aaagagcttg gtaccaagtt
    11281 ttagctcagg atttgcctgc tgagatatcg ccgcaggaac ttagtgaagt agagatgact
    11341 cgaaacaagg ctctcttgaa tcaggacaat atgagaatca aaaagaaggt gcaggaagct
    11401 agccatgtag gagatacaga tacagcccta gaagaattgg aacgtttaat ttcccaaaag
    11461 agaagaatgg agtaataatg gcaacaaaac aaaaagaagt aacaacattt gacgtacagg
    11521 tagcagaatt tatccgtaat cataagcaaa aagggacagc aacagatgat gaaatcaatg
    11581 caagtctggt tattcctttt accttggacg ctgatgggat tgaagatctc ttgcaacgga
    11641 ttcaggatgc agggatttct atcacagata acgaaggaaa tccaagtgcg cgtgttctta
    11701 gcaatgaaga agaaccagaa ctcagcgatg aggacttgat tggatcaact tctgctaagg
    11761 tcaatgaccc tgtccgtatg tacttgaaag aaataggggt cgttcctctc ttgaccaatg
    11821 aagaggagaa agagttggca ctggctgttg aagctggcga tatcgaagcc aaacaacgtc
    11881 ttgcggaagc caatcttcgt ttggttgttt ccattgccaa acgctatgtc ggtcgtggca
    11941 tgcagttcct tgacttgatt caagaaggaa atatgggctt gatgaaggcg gttgacaagt
    12001 ttgactattc taaagggttc aagttttcaa cttatgcaac ttggtggatt cgtcaggcta
    12061 tcactcgtgc tattgcggac caagctcgta ccatccgtat cccagttcac atggttgaaa
    12121 ctatcaataa attggttcgt gaacagcgga atctccttca agaattgggg caagatccga
    12181 caccagaaca gattgctgaa cgaatggata tgacacctga taaggttcgt gaaatcttga
    12241 agattgccca agaaccagta tctcttgaaa ctcctatcgg tgaagaggac gatagccacc
    12301 ttggagactt tatcgaagat gaagtgattg aaaatccagt ggattatacg actcgtatcg
    12361 tcttgcgtga gcaattggat gaaatcttag atactcttac agaccgtgaa gaaaatgttc
    12421 tgcgtctacg ttttggacta gatgatggaa aaatgcgcac acttgaagat gtggggaaag
    12481 tctttaacgt aactcgtgag cgtatccgtc agattgaagc aaaggctttg agaaaactac
    12541 gccaaccaag tcgcagcaaa ccgcttcgtg attttattga agactaagag tgaggaaaat
    12601 atggcttata cagaagagca aattgaaaac atcaaaacac ggattttaac agccttggaa
    12661 gaagtcatcg accctgagtt gggaatcgat attgtcaatc ttggtttgat ctatgagatt
    12721 cgttttgacg gtgacacagg gcaaacagag attgacatga ctttgacaac tatgggttgt
    12781 cccttagcag accttttgac agaccagatt tatgatgcta tgatagaggt tccagaagta
    12841 acggatactg aggttaaatt agtctggtat ccagcctgga cagttgaaaa aatgagtcgc
    12901 tatgcccgca ttgccctagg cattaagtaa acatataaaa gcatgtgaga gactagagga
    12961 aaagcgagga aatttcccct cttttcctct agtctctcct ttcttttgct gattttattc
    13021 aaagaaaatg atataatagt agttatggag aaaaagaaat tacgcatcaa tatgttgagt
    13081 tcaagtgaga aagtagcagg acagggagtt tcaggtgctt accgtgaatt agttcgtctt
    13141 cttcaccgtg ctgccaagga ccaattgatt gttacagaaa atcttccaat cgaggcagat
    13201 gtgactcact ttcatacgat tgattttccc tattatttat caaccttcca aaagaaacgc
    13261 tcagggagaa agattggcta tgtgcatttc ttgccagcta cacttgaagg aagtttgaaa
    13321 attccatttt tcttaaaggg aattgtgaaa cgctatgtat tttcttttta caaccggatg
    13381 gagcacttgg ttgtggtcaa tcctatgttt attgaggatt tggtagcagc tggtattcca
    13441 cgtgaaaaag tgacctatat tcctaacttt gtcaacaagg aaaaatggca tcctctacca
    13501 caagaagagg tagtcagact gcgcacagat cttggtctta gtgacaatca gtttatcgta
    13561 gtaggtgctg ggcaagttca gaaacgtaaa gggattgatg actttatccg tctggctgag
    13621 gaattgcctc agattacctt tatctgggct ggtggcttct cttttggtgg tatgacagat
    13681 ggttatgaac actataagaa aattatggaa aatcccccta aaaatttgat ttttccaggc
    13741 attgtatcgc cagagcggat gcgcgaattg tatgctctag cggatctttt cttgttgcct
    13801 agttacaatg agctctttcc tatgactatt ttagaagctg cgagttgtga ggctcctatt
    13861 atgttgcgtg atttagatct ctataaggtg attttggagg gaaattatcg ggcgacagcg
    13921 ggtagagaag agatgaaaga ggctattttg gaatatcaag caaatcctgc tgtcttaaaa
    13981 gatctcaaag aaaaggctaa gaatatttcc agagagtatt ctgaagagca tctgttacaa
    14041 atctggttgg acttttatga gaaacaagcc gctttaggga gaaagtaaaa agtgaggtaa
    14101 tctatgcgaa ttggtttatt tacagatacc tattttcctc aggtttctgg tgttgcgacc
    14161 agtattcgaa ccttgaaaac agaacttgaa aagcagggac atgctgtttt tatctttacg
    14221 acgacagata aggatgtcaa tcgctacgaa gattggcaaa ttatccgcat tccaagtgtt
    14281 cctttctttg cttttaagga tcgtcgcttt gcctaccgag gttttagcaa ggcacttgaa
    14341 attgctaaac agtatcagct agatattatc catactcaga cagaattttc tcttggcctg
    14401 ttggggattt ggattgcgcg tgaattgaaa attccagtca tccataccta tcacacccag
    14461 tatgaagact atgtccatta tattgctaag gggatattga tccggccgag tatggtcaag
    14521 tatctggtta gaggtttcct gcatgatgtg gatggggtta tttgccctag tgagattgtc
    14581 cgtgacttgc tatctgatta taaggtcaag gttgaaaaac gggtcattcc tactgggatt
    14641 gaattagcca agtttgagcg tccggaaatc aagcaggaaa atttgaaaga actgcgtagt
    14701 aaactaggga ttcaagatgg tgaaaagacg ttgcttagtc tttcgagaat ctcctatgaa
    14761 aaaaatattc aagcagtttt agcagccttt gctgatgttc tgaaagagga agacaaggtt
    14821 aaactggtag tagctgggga tggcccttat ctgaatgacc tcaaagagca agcccagaac
    14881 ctagagattc aagactcagt catctttaca gggatgattg ctcctagtga gacggctctt
    14941 tactataaag cggcggattt cttcatttcg gcatcgacaa gcgaaacgca aggtttgacc
    15001 tacttggaaa gcttagccag tggaacacct gtcattgctc acggaaatcc ttatttgaac
    15061 aacctcatca gtgataaaat gtttggagcc ttgtactatg gagaacatga tttggctggt
    15121 gctattttgg aagccctgat tgcaacacca gacatgaatg agcatacctt atcagagaaa
    15181 ttgtatgaga tttcagctga gaactttggg aaacgagtgc atgagtttta tctggatgcc
    15241 attatttcaa ataacttcca gaaagatttg gctaaagatg atacggtcag tcagcgtatc
    15301 tttaggacag ttttgtatct tccgcaacag gtggttgctg tacctgtaaa aggatctaga
    15361 cgcatgttga aggcttcaaa aacacagttg atcagtatga gagactattg gaaagaccat
    15421 gaagaataga aagaggaaca gctatgaaaa aaacaattaa tgagaagcgg tcgtgataaa
    15481 aagattgcgg gtgtttgtgc tggggtggcc cattatctgg atatggatcc gactatcgtt
    15541 caagtcattt ggggtgttct tacttgctgt tacggagctg gaattgtagc ttacattatt
    15601 ttatggatta tcgcaccagt agcaactgac tattgaaaac tagctcaatt catgctaaga
    15661 taatagaaaa tagaatgtaa cgaaggagag aaaaatggca tttggagata atggaaatcg
    15721 taaaaaaact atgtttgaga aaataacctt gtttatcgtg attatcatgc tagtagcaag
    15781 tttattggga atttttgcaa ctgcaattgg tgccctcagt aatctataaa atagattcaa
    15841 gaaaatttag tgactgggat ttcccagccc ttttttaaag tgagaagaaa taatgagtat
    15901 gtttttagat acagctaaga ttaaggtcaa ggctggtaat ggtggcgatg gtatggttgc
    15961 ctttcgtcgt gaaaaatatg tccctaatgg aggcccttgg ggtggtgatg gtggtcgtgg
    16021 aggcaatgtg gtcttcgttg tagacgaagg actacgtacc ttgatggatt tccgctacaa
    16081 tcgtcatttc aaggctgatt ctggtgaaaa agggatgacc aaagggatgc atggtcgtgg
    16141 tgctgaggac cttagagttc gagtaccaca aggtacgact gttcgtgatg cggagactgg
    16201 caaggtttta acagatttga ttgaacatgg gcaagaattt atcgttgccc acggtggtcg
    16261 tggtggacgt ggaaatattc gtttcgcgac accaaaaaat cctgcaccgg aaatctctga
    16321 aaatggagaa ccaggtcagg aacgtgagtt acaattggaa ctaaaaatct tggcagatgt
    16381 cggtttagta ggattcccat ctgtagggaa gtcaacactt ttaagtgtta ttacctcagc
    16441 taagcctaaa attggtgcct accactttac cactattgta ccaaatttag gtatggttcg
    16501 cacccaatca ggtgaatcct ttgcagtagc cgacttgcca ggtttgattg aaggggctag
    16561 tcaaggtgtt ggtttgggaa ctcagtttct ccgtcacatc gagcgtacac gtgttatcct
    16621 tcacatcatt gatatgtcag ctagcgaagg ccgtgatcca tatgaggatt acctagctat
    16681 caataaagag ctggagtctt acaatcttcg cctcatggag cgtccacaga ttattgtagc
    16741 taataagatg gacatgcctg agagtcagga aaatcttgaa gaatttaaga aaaaattgtc
    16801 tgaaaattat gatgaatttg aagagttacc agctatcttc ccaatttctg gattgaccaa
    16861 gcaaggtctg gcaacacttt tagatgctac agctgaattg ttagacaaga caccagaatt
    16921 tttgctctac gacgagtccg atatggaaga agaagcttac tatggatttg acgaagaaga
    16981 aaaagccttt gaaattagtc gtgatgacga tgcgacatgg gtactttctg gtgaaaaact
    17041 catgaaactc tttaatatga ccaactttga tcgtgatgaa tctgtcatga aatttgcccg
    17101 tcagcttcgt ggtatggggg ttgatgaagc ccttcgtgcg cgtggagcta aagatgggga
    17161 tttggtccgc attggtaaat ttgagtttga atttgtagac taggagactg gtatgggaga
    17221 taaaccgata tctttccgag atgcggatgg taattttgtt tccgccgcag acgtttggaa
    17281 tgaaaagaaa ttggaagaac tatttaatcg tctcaatcca aatcgtgcct tgagattggc
    17341 acgaactaaa aaggaaaatc catctcagta aagaagctaa aaaatcccgt gcctcatcag
    17401 acacgggatt ttgtggtacg acaggcatgt atagcaaact gaatctggaa tagcacagca
    17461 tatcttctaa aatattgtta taaattgatt tgaatttcaa aattaaattg tttgattctt
    17521 atctcaattt gttatagtat atctgatgtc aaagttctcg gcgagtcaaa tagcgattcc
    17581 caagcctgac tatcgtgagg tagcggatta aaatggtctg gggatagacc gttttaagtc
    17641 tgacgctgga aataagaatt gtcagaagaa gggatagcga aatcgtggct ctacgaacag
    17701 gaacgtgata ataaggcgta tatagcggat aagagggcct caaactctaa agtccaaaaa
    17761 ggtagtcgta acctatatgc gtaaatcacg agagtaattg aattcgtact aagattttct
    17821 attttcactg taagctttta acgtccttat atcttgtata cacgaggaaa gatgtacgac
    17881 ttatcccgtg aggtctatca ctataaagag aaaacgacag atagaagtga tcctgagtca
    17941 cggttatctt taaaatagat tgtctgatag gacggtatgt ataaaacgct tctgtgaact
    18001 gagagaaggg ggagaagttc ttgctaaaat ttagttgaac agccgtattc cgatacttag
    18061 ataagagatc tagtcttagc tcctactcag ttttagggga taaaaaaggg gaaatagcga
    18121 ttcgagaaag attatactct tcgaaaatct cttcaaatca cgtcaatatc gccttgccgt
    18181 atgtgtagga tactgactac gtcagttcca tctacaacct caaaacagtg ttttgagcaa
    18241 cctgcggcta gtttcctagt ttgatctttg attttcattg agtattagta attcagttac
    18301 taactcgtca actctgattt atccaataaa attgaaaagg atggaaaaaa ggataaattt
    18361 atgatatact ttattttgaa gaccttatta gaaatcttga aagagtattg aaaacttaga
    18421 atgagaaaaa ttgttatcaa tggtggatta ccactgcaag gtgaaatcac tattagtggt
    18481 gctaaaaata gtgtcgttgc cttaattcca gctattatct tggctgatga tgtggtgact
    18541 ttggattgcg ttccagatat ttcggatgta gccagtcttg tcgaaatcat ggaattgatg
    18601 ggagctactg ttaagcgtta tgacgatgta ttggagattg acccaagagg tgttcaaaat
    18661 attccaatgc cttatggtaa aattaacagt cttcgtgcat cttactattt ttatgggagc
    18721 ctcttaggcc gttttggtga agcgacagtt ggtctaccgg gaggatgtga tcttggtcct
    18781 cgtccgattg acttacacct taaggcgttt gaagctatgg gtgccactgc tagctacgag
    18841 ggagataaca tgaagttatc tgctaaagat acaggacttc atggtgcaag tatttacatg
    18901 gatacggtta gtgtgggagc aacgattaat acgatgattg ctgcggttaa agcaaatggt
    18961 cgtactatta ttgaaaatgc agcccgtgaa cctgagatta ttgatgtagc tactctcttg
    19021 aataatatgg gtgcccatat ccgtggggca ggaactaata tcatcattat tgatggtgtt
    19081 gaaagattac atgggacacg tcatcaggtg attccagacc gtattgaagc tggaacatat
    19141 atatctttag ctgctgcagt tggtaaagga attcgtataa ataatgttct ttacgaacac
    19201 ctggaagggt ttattgctaa gttggaagaa atgggagtga gaatgactgt atctgaggac
    19261 agcatttttg tcgaggaaca gtctaatttg aaagcaatca atattaagac agctccttac
    19321 ccaggctttg caactgattt gcaacaaccg cttacccctc ttttactaag agcgaatggt
    19381 cgtggtacaa ttgtcgatac gatttacgaa aaacgtgtaa atcatgtttt tgaactagca
    19441 aagatggatg cggatatttc gacaacaaat ggtcatattt tgtacacggg tggacgtgat
    19501 ttacgtgggg ccagtgttaa agcgaccgac ttaagagctg gggctgcact agtcattgct
    19561 gggcttatgg ctgaaggtaa aactgaaatt accaatatcg agtttatctt acgtggttat
    19621 tctgatatta tcgaaaaatt acgtaattta ggagcggata ttagacttgt tgaggattaa
    19681 accgtagagg tgtttatgaa tatttggacc aaattagcaa tgttttcttt ttttgaaacg
    19741 gatcgcttgt atttgcgtcc tttctttttt agtgatagtc aggacttccg cgagatagct
    19801 tcaaatccag aaaatcttca atttattttc ccaacgcagg caagtctgga agaaagtcaa
    19861 tatgcactgg ccaattactt tatgaagtcc cctttgggag tgtgggcaat ttgtgaccag
    19921 aaaaatcaac aaatgattgg ttctattaaa tttgagaagt tagatgaaat caaaaaagaa
    19981 gctgagcttg gctatttttt gagaaaagat gcttggtcgc aaggatttat gacagaggtt
    20041 gttagaaaaa tttgtcagct ttcttttgag gaatttggct taaaacaatt atttatcatt
    20101 acccaccttg aaaatgaagc tagccaaaga gttgctctta agtctggatt tagtttgttc
    20161 cgtcagttta agggaagtga tcgttacaca agaaaaatgc gggattatct tgaatttcgg
    20221 tatgtaaaag gagagttcaa tgagtaagca tcaggaaatt ctaagctatt tggaggaatt
    20281 accagtaggt aaaagggtca gtgttcgtag catttcgaat catctaggag ttagtgatgg
    20341 aacagcctat cgagctatta aagaagctga aaaccgtgga attgtggaga cccgtcctag
    20401 aagtggaaca attcgtgtta aatcccagaa agttgctata gatagattaa cgtttgctga
    20461 aattgcagaa gtgacttctt ctgaggttct ggctgggcaa gaaggtttag agagagaatt
    20521 tagtaagttt tcaattggtg ccatgactga acaaaatatc ttgtcttacc ttcatgatgg
    20581 ggggctcttg attgtcggag accgaacccg tattcagttg ctagccttgg aaaatgaaaa
    20641 tgcagttctg gttacagggg gatttcaggt tcatgatgat gtgcttaaac tggccaatca
    20701 aaaagggatt cctgttctaa gaagtaagca tgataccttt accgtcgcta ccatgatcaa
    20761 taaagccttg tcaaatgtcc aaatcaagac tgatattctg acagttgaga aactttatcg
    20821 ccctagtcat gagtatggtt ttctgagaga gacagataca gttaaagatt atttggactt
    20881 ggttcgtaag aatcgtagca gccgtttccc tgttatcaat caacatcagg tcgttgttgg
    20941 cgttgtaacc atgagagacg ctggtgataa atcaccaagc acgacaattg ataaggttat
    21001 gtctcgtagt ctatttttgg ttggattatc gacaaatatt gccaatgtga gtcaacggat
    21061 gatcgcagaa gactttgaaa tggtaccagt tgttcgaagc aatcaaactt tgcttggcgt
    21121 tgtgacgcga cgagatgtca tggagaagat gagccgttcc caagtttcgg ctctaccaac
    21181 tttttctgag cagattggac aaaagctctc ttatcaccat gatgaagtag tcattacagt
    21241 ggaacccttt atgctagaaa aaaatggagt tttggctaat ggtgtattgg cagaaattct
    21301 gacccacatg acccaagatt tagttgttaa tagtggtcgc aatctcatta tcgagcagat
    21361 gctgatctac tttttgcagg ctgttcagat agatgatata ttgcgcattc aggcacggat
    21421 tattcatcat acgagacggt cagctataat tgattacgat atttatcatg gtcaccagat
    21481 tgtttcaaaa gcaaatgtga ctgttaaaat taattagaaa ctaggagaaa agatgataac
    21541 attaaaatca gctcgtgaaa tcgaagctat ggacaaggct ggtgattttc tagcaagtat
    21601 tcatataggc ttacgtgatt tgattaagcc aggcgtagat atgtgggaag ttgaagaata
    21661 tgtccgccgt cgttgtaaag aagaaaattt ccttccactt cagattgggg ttgacggtgc
    21721 catgatggac tatccttatg ctacctgttg ctctcttaac gatgaagtgg ctcacgcttt
    21781 ccctcgtcat tatatcttga aagatggtga tttgctcaaa gttgatatgg ttttgggagg
    21841 tcccattgct aaatccgacc tgaatgtctc aaaattaaac ttcaacaatg ttgaacaaat
    21901 gaaaaaatac actcagagct attctggtgg tttagcagac tcatgttggg cttatgctgt
    21961 tggtacaccg tccgaagaag tcaaaaactt gatggatgta accaaagaag ctatgtacaa
    22021 gggtattgag caagctgttg ttggaaatcg tatcggtgat atcggtgcgg ctattcaaga
    22081 atacgctgaa agtcgtggtt acggtgtagt gcgtgatttg gttggtcatg gtgttggccc
    22141 aactatgcac gaagaaccaa tggttcctaa ctatggtatt gcaggtcgtg gactccgtct
    22201 tcgtgaagga atggtcttaa ccattgaacc aatgatcaat acaggcgatt gggaaattga
    22261 tacagatatg aaaactggtt gggcgcataa gaccattgac ggtggattgt catgtcagta
    22321 tgaacaccaa tttgtcatta cgaaagatgg acctgttatc ttgactagcc aaggtgaaga
    22381 aggaacttat taataaaaag tgaaaagact actggaagtt tattttgata aaaaatccag
    22441 tagatctttt cataataaaa cgcattgtat caagtgttag gggctgatat catgcgtttt
    22501 tctgctttta agattttttc caactttgtt tgtaagcgca tcataacaaa gggtctagga
    22561 ttcagggctc tcctcctata tactattagt aaagtaaaac taagggagga tattttagtg
    22621 tcgcagtcta ttgttcctgt agagattcca caatattgtc gttttgattc taaaaagaga
    22681 aatggaattc tgtttaacgt ttgtattgcc aatcttaaat ttattttttt atattatact
    22741 tcctgcgaaa caaaatatgg tatagtagtt ctatgaatga tgaagcaagt aaacaactaa
    22801 ctgatgcacg atttaagcgt cttgttggtg ttcagcgtac cacttttgaa gagatgttag
    22861 ctgtattaaa aacagcttat caacttaaac acgcaaaagg tggacgaaaa cctaaattaa
    22921 gcctagaaga ccttcttatg gccactcttc aatagtgcga gaatatcgaa cttatgaaca
    22981 aattgcggct gattttggta tccacgaaag caacttactc cgtcggagcc aatgggttga
    23041 agtaactctt gttcaaagtg gttttacgat ttcaagaact cctctcagtt ctgaggacac
    23101 ggtaatgatt gatgcgacgg aagtaaaaat caatcgccct aaaaaaagaa ttagcgaatt
    23161 attctggtaa aaagaaatgc cacgctatga aggctcaagc gattgtcaca agtcaaggga
    23221 gaattgtttc tttggatatc gctgtgaact attgtcatga tatgaagttg ttcaaaatga
    23281 gtcgcagaaa tatcggacaa gctggaaaaa tcttggctga cagtggttat caagggctca
    23341 tgaagatata tcctcaagca caaactccac gtaaatccag c
//
LOCUS       DBEJKC010000028        23351 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.028, whole genome shotgun sequence.
ACCESSION   DBEJKC010000028 DBEJKC010000000
VERSION     DBEJKC010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 23351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23351
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.028"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(60..1067)
                     /locus_tag="ACL3G6_001197"
     CDS             complement(60..1067)
                     /locus_tag="ACL3G6_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGR0545736.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(1057..2082)
                     /locus_tag="ACL3G6_001198"
     CDS             complement(1057..2082)
                     /locus_tag="ACL3G6_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HGR0545737.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(2475..2693)
                     /locus_tag="ACL3G6_001199"
     CDS             complement(2475..2693)
                     /locus_tag="ACL3G6_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0545738.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(3431..5062)
                     /gene="rlmD"
                     /locus_tag="ACL3G6_001200"
     CDS             complement(3431..5062)
                     /gene="rlmD"
                     /locus_tag="ACL3G6_001200"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGR0545739.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMNLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(5136..6110)
                     /locus_tag="ACL3G6_001201"
     CDS             complement(5136..6110)
                     /locus_tag="ACL3G6_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HGR0545740.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSAHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(6184..6798)
                     /gene="pmp23"
                     /locus_tag="ACL3G6_001202"
     CDS             complement(6184..6798)
                     /gene="pmp23"
                     /locus_tag="ACL3G6_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HGR0545741.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(6798..7772)
                     /locus_tag="ACL3G6_001203"
     CDS             complement(6798..7772)
                     /locus_tag="ACL3G6_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HGR0545742.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(7780..9036)
                     /gene="glyA"
                     /locus_tag="ACL3G6_001204"
     CDS             complement(7780..9036)
                     /gene="glyA"
                     /locus_tag="ACL3G6_001204"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HGR0545743.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPKTELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(9098..9529)
                     /locus_tag="ACL3G6_001205"
     CDS             complement(9098..9529)
                     /locus_tag="ACL3G6_001205"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0545744.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIC"
     gene            complement(9531..10133)
                     /locus_tag="ACL3G6_001206"
     CDS             complement(9531..10133)
                     /locus_tag="ACL3G6_001206"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HGR0545745.1"
                     /translation="MMDRIRQELEKGGAVVLPTETVYGLFSKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLSEISFEEA"
     gene            complement(10117..10956)
                     /gene="prmC"
                     /locus_tag="ACL3G6_001207"
     CDS             complement(10117..10956)
                     /gene="prmC"
                     /locus_tag="ACL3G6_001207"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HGR0545746.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(10956..12035)
                     /gene="prfA"
                     /locus_tag="ACL3G6_001208"
     CDS             complement(10956..12035)
                     /gene="prfA"
                     /locus_tag="ACL3G6_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HGR0545747.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEELAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(12032..12622)
                     /locus_tag="ACL3G6_001209"
     CDS             complement(12032..12622)
                     /locus_tag="ACL3G6_001209"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HGR0545748.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            12746..12928
                     /locus_tag="ACL3G6_001210"
     CDS             12746..12928
                     /locus_tag="ACL3G6_001210"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HGR0545749.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            13065..14438
                     /gene="mnmE"
                     /locus_tag="ACL3G6_001211"
     CDS             13065..14438
                     /gene="mnmE"
                     /locus_tag="ACL3G6_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HGR0545750.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(14485..15420)
                     /gene="dapA"
                     /locus_tag="ACL3G6_001212"
     CDS             complement(14485..15420)
                     /gene="dapA"
                     /locus_tag="ACL3G6_001212"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HGR0545751.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(15476..16552)
                     /locus_tag="ACL3G6_001213"
     CDS             complement(15476..16552)
                     /locus_tag="ACL3G6_001213"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HGR0545752.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDMDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(16894..16966)
                     /locus_tag="ACL3G6_001214"
     tRNA            complement(16894..16966)
                     /locus_tag="ACL3G6_001214"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16931..16933),aa:Thr,seq:ggt)
     gene            complement(17066..17575)
                     /locus_tag="ACL3G6_001215"
     CDS             complement(17066..17575)
                     /locus_tag="ACL3G6_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HGR0545753.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(17573..17669)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            17698..18129
                     /locus_tag="ACL3G6_001216"
     CDS             17698..18129
                     /locus_tag="ACL3G6_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HGR0545754.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            18211..18588
                     /gene="mscL"
                     /locus_tag="ACL3G6_001217"
     CDS             18211..18588
                     /gene="mscL"
                     /locus_tag="ACL3G6_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HGR0545755.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(18630..19724)
                     /gene="hemH"
                     /locus_tag="ACL3G6_001218"
     CDS             complement(18630..19724)
                     /gene="hemH"
                     /locus_tag="ACL3G6_001218"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HGR0545756.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGMRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENIKMPYLIKKMLEKAGKLPKE"
     gene            19878..21101
                     /gene="pepT"
                     /locus_tag="ACL3G6_001219"
     CDS             19878..21101
                     /gene="pepT"
                     /locus_tag="ACL3G6_001219"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HGR0545757.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(21137..21791)
                     /locus_tag="ACL3G6_001220"
                     /pseudo
     CDS             complement(21137..21791)
                     /locus_tag="ACL3G6_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672614.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family hydrolase"
     gene            21789..21953
                     /locus_tag="ACL3G6_001221"
                     /pseudo
     CDS             21789..21953
                     /locus_tag="ACL3G6_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(22030..22673)
                     /locus_tag="ACL3G6_001222"
                     /pseudo
     CDS             complement(22030..22673)
                     /locus_tag="ACL3G6_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672611.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(22780..23340)
                     /locus_tag="ACL3G6_001223"
                     /pseudo
     CDS             complement(22780..23340)
                     /locus_tag="ACL3G6_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672571.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         6836 a         4789 c         4233 g         7493 t
ORIGIN      
        1 tgaggaaaat agtgttattc tattttttct tttttgaata cctataatta aattttgcat
       61 tagttattaa cccctctatt tttcatagtt acataaataa gtactggacc cccgattatt
      121 gcagtaatta tccctacttc aatttcacct ggtttaccta acatacggcc gattatatca
      181 catataagca agagctctgc acctataaaa gatgaagaaa tggtcattgt gcgtatatct
      241 ttgcttataa ataagccaca aaagtgagga actataagac ctacgaagcc aataggtcca
      301 ccaattgcag taatacttga acataaaagc acacttgcaa ttattgcaag tgatcttatc
      361 ctattaacat taactccaag accaacagcc atttcatcac ccatagctaa agcgtttaaa
      421 tctgatgaaa taaatatagc tatcaagtga cctaaaatta taaaaggtag tagtgtagat
      481 atagaagata atgtagctgc tccaaggcta cctatttgcc aaaatctaaa tttgtctaag
      541 acgttattat tcggtaaaat taaaaaactt acaaaactgc ttaaagccat actaacacaa
      601 gttcctgata aggcaagttt tataggggta aggcctgctt ttccgcttac agcaatcgcg
      661 tatacaaaaa ttgcacttac taagccacca atgattgcaa aacttatatg gcttatgctt
      721 gatgaaattc ctaaaaaaga aagaccaatt actacactaa gacttgctcc tgtgtttata
      781 ccgagtatac ctggatcagc tattgggttt ctagtaactg attgcatcaa tacaccgctt
      841 atggcaagac tagaacctgc taaaattgca aaaatagttc taggtattct tttatatata
      901 attgatttaa taaaatcatc atttgtatta cccattccaa aagctgctaa aaaatctctg
      961 atattaattt cttttgttcc aagctttaat gacaaaaata ttgtaataag aagacctagg
     1021 cagattacaa aaattatgcc taggtttatt tgttttttat ttcgcatttt tgcatgcatt
     1081 tcctaaaaga tttagatatt cttcaatagt atagtttatt gaaagtggtg ttggagtgca
     1141 tgaggctgct aacggtgtat tatctggaat tacagcaacg gcaccatttt taattgcatt
     1201 tattttacct aaaagaggat ctttttgtaa agcttcaaga gttttatcat caccataagt
     1261 tatgattaca tcagcatcat ttatcttatt tgcttcttct gcagaaattt cctttgcaaa
     1321 actatcttca ctctcaaatt cttttaatga ttcagggaaa actagaccta aatctgttaa
     1381 ataatttgct cttggatctt tgctagtata aatccagaat tttgatgtat ctgcagcatt
     1441 aatcatagta aataatactt tttttccttt gatttttcct ttgatttctg gatgtttttc
     1501 taattctttg gatatacgag cttcagtatt tttgattaac tcatcacctt ctttttccat
     1561 acctaaggct tttgaatcaa ttttaatcat atctctccat aaagtttgcc aaggtttaga
     1621 tttgtatgct gctacaggag caatttttga tagagtgtca taatcttctt tagttatacc
     1681 agaataacct gctaagataa catctggttt agaatttgat attgcttcaa agttaagtcc
     1741 atccaaatcg tcaaataggt tagctttacc atttagttct ttgatttttt cttctgtcca
     1801 tggtaaaact cctttatcag cacttacacc gtaatttgct tttgaaaatc caacaggaac
     1861 tattcctaaa gctaatgcta catcatgatt tccccaagca atagttgcaa ctctttcagg
     1921 ttttttatct aatatagttt gaccgaaagc atgatctaaa actattttat caggcgcatg
     1981 ctctttagaa gtattttctt catttttaac agaattagaa gaacaagcgc taaaaactat
     2041 acacatagct aaaatagcta ttagaaaaaa tttgtttttc ataaaaactc cttaaacata
     2101 tttcaagtct attgtatcga taataattat cattgtcaat agatacagtt acaaatttaa
     2161 taatataatt ttttcaaaaa aggatctagt ttttattttt agttaaatta tgtctatatt
     2221 tttcattaac tcatcaataa aaatttgttt gctaatatct ctttcttctg attttgtttc
     2281 aaggattatt gctacatcat tcatattttt aggtaaatac caaccatctg gcttatctga
     2341 atatcccttg aagcctaatt gattaaaagt agttatttga ccagtacctt gattgatgtt
     2401 ttcttcaact tcattaaagc ctatacttct cttgcataat ccctaacttg atcttctgtc
     2461 cttaaagtca ttttctattc ctcgtcacta aaattatctt caaaactaat aatatcatta
     2521 ggagtgcaag ataaagcctt acatattctt tctaaattct taaatgtaat tggtttatcc
     2581 tttcccattt gtgccataac atttgttgta agtcctgcca tagctattac atctgttttc
     2641 tttagtcctt tttttgctaa ctgtatccat aatggtttat agttaagtgc cataatatcc
     2701 ctcttttttt cttcattaga tttatttaat tatagcataa atattgattt cattcaatct
     2761 tacattgatt tagtgatttg ttttagagaa tttgttgtgt tattccgtcc ttattttgcc
     2821 ataaattgtt ttaagtggga cctcttatcc ttaccatttt tacctcctaa ttttgagtat
     2881 aaaaaagacg atagagtttt taatttctat cgtctgagat ttacatatta aattttcatc
     2941 acaaaataag actctttaaa gaatctttaa attcattggt atgctaatta caatatccat
     3001 tattaaaatg gatactataa gcagcacacc aactatttat tttttgagtt ttaaactttg
     3061 gtagaagtct tgaactcctt atatttacat aactatttgc ctctataact attatgacac
     3121 gaaaccaaca agcaagttca agcacctcca tatctttatt caaatgagga ctaagatatt
     3181 cacaaacttt atcataaacc tctttatctt ttttcataaa aggggcatac aacttagcaa
     3241 atttatccta aaattttttg ttgcctttat caatcatttc aacactcctt taaatataaa
     3301 aatgatccta tcaatcttta tattgagcct attttctaat tgataccttg caagaaagga
     3361 ataatagctg ttcctatacc aagtaggaat gtaataaatg cagaaagtca tatactgtca
     3421 ttcttttcta ttaaatcatt ttgaagtgtc tcaaagcatc catgatggct tcttcttttt
     3481 caggtgtaca ctgtggaata atttgtttat cctttttaga cttgttgtaa tgttctcgta
     3541 attctattcc acatttcttt tttatctgtg caatatataa tgtcgaaact tttaattcaa
     3601 atttattcca aacatattct ttgatttgag catatgttgc tttgctctcc gcacttgtca
     3661 aattcatctc atccagctca atttcaacac ttatgtgctt atcgacatcg agtttggaca
     3721 aaagtgctac cgtctcgacg tgatgcgttt gaggaaatag atccaccggc tggactttct
     3781 tcaattcata tcccaattct tggtagagtt tgatatcacg cgccatggtt gcgacattgc
     3841 aggagatata ggcgatgcga tcggctcctg tttgggcgct tgctttgata aagctttctg
     3901 tcaagccctt gcgtggagga tcaaccaaga taacggttgg ttgaatccca tctttaagcc
     3961 aattcttcat agcattttca gctgtgtcac agacatagtg ggcgtttgaa atattgttca
     4021 gctgagcatt ttttttacta ttctcaaccg cttctggaat cagttcaaca ccgtagactt
     4081 ctttgacatg cttggcgact gataaaccaa tggttccaat accagaatag gcatcaataa
     4141 tcacgtcatc tttttttaac tctgcaaagt caatggctgt ttgatagagt ttctccgcca
     4201 tttcagtatt gacttggtaa aaggctgggc cagcgatttg gaagtcattt cccaacatct
     4261 ggtccgtaat atagtcttga ccataaagag tgcgccactc cttaccaaaa atcgcattgg
     4321 tattctggtc gttgatattt tgcatgacag acacaatctc tgggaactgc ttgataactt
     4381 gttcaatcaa ttggtcaaca cgaaaaactt ttggacgagt tgtcaccaaa acgaccatga
     4441 tttgtcctga atagtgacca cgacgcacca caagattccg aatcaatcca gactgttcct
     4501 tttcgtcata aggttttaaa tcaaaacgac ggagcaggtc tcgaagagct actacgactt
     4561 ggtcaatgac aggatcctgg ataaagaaat cttcaagggg catgaggttg tgcgaattct
     4621 tacggaaaaa tcctgtttcc aagacaccat tcactcgacg aacgggcacc tgcgccttat
     4681 tgcgatactt gactggatgt tccataccaa gcgtttcagc aacttctaca tctgcaattc
     4741 cagcaatctt gtagagactg tccttgactt gcttggtttt aaacttgagc tgttctggat
     4801 aagaaaggtg tcctaaatcc gcgattcctg aacgcaggta agccaaatct agatcttgat
     4861 tacggtgtgg tgactggaca aggtattttt caacttttcc aaagccaatc tttttattga
     4921 ccttgaggac acgcatgaga attttttcac tcggtaaagc attctctaca aaaaagacca
     4981 aaccatctac cttggcaact cctgcccctt catgggtcaa gtcaacaatt tcaacttcta
     5041 caatatcatt tttctttaac attcttttct ctttctattg gccgacaaaa aagacggcaa
     5101 cgttacggtt accatccatt ataccatgaa atttcttaag aaccaaaact cttgaagaag
     5161 ttgacaaggg cttgccagag ggagcttaag aagttaccac cgtcctctag cgccttatcc
     5221 gcatcaaagt taaggttgat atttttaaaa ctgtcgccag cttgtgatac gatgctttgt
     5281 ttaaggtcat ttagggtttt agtgaaatct gcattgctga ggatatcact ctttgagaga
     5341 ttcaaggcaa aattgatgat gatattgatc tggtttcctg ttatgacctg atcaagtttg
     5401 taatttttta aggtatcttc aacaatcttg cgtacatctt cttctgtcag atttcccttg
     5461 ctttctttag ctttggcgag tcctgacttg atatcagcta gggcaacgtt taatttatta
     5521 gcatcatagc ctgatttgtc cttgttttca gcattgatat ctgacaaagc ctttagctct
     5581 tcttgagcca aatctttatt ggcttgcggc accttggctc cattagcttc tagcgaatag
     5641 tagatcccag ccaaagcact ctcacctgta actggaatag gggctgctac agtgattttg
     5701 gcatgttcca tacccagcgt tactgctgcg tttcggtaca tatcctgagt caccttagtg
     5761 atattttctg gtgtttcaat cttgacctca agtggcgatt tgtcacctag cttttgaatc
     5821 ttggctgatg aatacaactg taagctagag tcattggcca cattcatgat tttagaataa
     5881 acatcaggtg tcatggtctt gagttctttg gtatctgttg aggcattgta gcccagtttt
     5941 ttaagagttt gatttttttg gtcttcagat agggaggaac ctaggacata ttcaggttgg
     6001 acataggttt catcgataac tttttgaaca tctgttgctg catgggcgct attcatagct
     6061 gttactgccc acaagaccgc agcactggtc agaaagagtt tctttctcat agggaatttc
     6121 ctcctttact tttctagagt aatatatcta tcttaaagaa aacttataac aaaaacacct
     6181 ggtctagcca gatgttgaaa agagagtgaa acatttgatg atgtaaaggt taagtcgtac
     6241 ctgtctagaa taataatagt ttcctccatt tacatagagt tcagcaccgt gaaaaatgga
     6301 aatggggtga atataactat aagtctttcc agtcgtatta ccaagcaagg gggcaacagt
     6361 ctcacgagag tactgtttgg ctagagccaa ggtattttcc ttgccatttt gggcgataaa
     6421 atcgatatag gcaggtccaa aattataggc ttgaacagct gtccagatat ctacaccctt
     6481 cttctgcgcc agatagagat tgcctgtcag agtttgaatg ccttgccgaa tgctagaggc
     6541 attatcattg atggtattgg tggaaccact tgcagactca ctagactgca taacatcgcc
     6601 ttcttttcct tttgtttcag tataaatcat agcaagcaca agctcttcgt ttgctggggt
     6661 gtctttttca ctcaatattt ctcgcaccat gggttgatag gtcatgactt gtttgacatc
     6721 ttgatgaacg cggtaagctt tatatccagc aaaaaggaag actgctagta caagcactct
     6781 tcgaattcgt ttaaacatta tttactttgg atatcctcga tatttttgat taagatagag
     6841 taggttccat tttcgttttg gataaactca acagactcgg cgtcttgata gacgttattg
     6901 ggaacgatga gctcaattcc atttgataag gagagttttt ggttttcaaa tttctttaat
     6961 tggcgactgg catcaatttc atcaaattga acaggttctg gtacggcttc tttgacttgg
     7021 tcaataaagc tcaaacgagc cgtcagattg ttgtcaaaaa ggtcattagc caatttctca
     7081 ggtgacaatt cattgctttc ttctaggttg ttgaaaatag ctgatttgac cttggattga
     7141 aattgaaaat catctgtgtt aaaagattca gcaattctct gggctgtttt ttccagttcc
     7201 ttgatagatt ttttaggaga aatcttagga gcgacagcaa gaagattatc tgaaaaatag
     7261 ttcaaaaaag tcccgttgta cttgattcgt ttttcaatca ggtgatactt gctactctga
     7321 agattgacca ccaaggcctc atcagctcct gttccaaatc caggcaggtt attctgagtt
     7381 agcttgattg gattatcaac ttctcctccg aggtgggtca aggtctcccg cagggcaatt
     7441 cgcaagaaag cgaaatgttc tacaccttct ttagaaaatt gaacaaaaat caagtcattg
     7501 gtcttgagat tttcagaaat gctaaactcc tctttccaga gattagccag cgttactgat
     7561 gtctccaaca aatcgtctgt aatatgattg aagaagggat tttcttcttc gaaaatccca
     7621 gtcttggctt catctgaata cacatgttca atttttttac gtaggtattc ttcgattttt
     7681 ggagtaatat tgagaaactt atctgctaag aacagctcgg tatcatccgg actgaactgg
     7741 tgaataatgg ctttcttaat ataaatgtcc ataaaagttt tattcctcgt ataatgggaa
     7801 ggcatctgtc aattctttga ctgcacttct cacttcttct aatacagcct cattttctga
     7861 attcttaagg gttttaatga tgagttcagc cactttgcga ctttcttctt caccaaatcc
     7921 acgtgcagta atagctgctg ctccgatacg aatcccactt gtcttgaatg gtgacaagct
     7981 ttcgtaaggg attgagtttt tatttaaggt aatattgact tcatccaaca agttttgagc
     8041 aactttgccg ttttctacaa ctttagtcac atcaacaagg aagagatggt tttcagttcc
     8101 acctgaaata atacggaaat cagggtcttg caagaagaca tctgccatag ccttgctgtt
     8161 cttaattaca ttggcagcat attccttgaa ggctggatcc aaaacttctt tgaaggaaac
     8221 tgccttagcc gccacaacat gctctaaagg accgccctga atacctggga aaatagctga
     8281 attgattttt ttagcaagtt cttcgtcatt ggtcaaaatc aaaccaccac gaggtccacg
     8341 aagggttttg tgggtcgttg ttgttgtgat atgagcgtat ggaactgggc ttggatgaag
     8401 gccagccgca accaagccag cgatatgggc catgtccacc atgagcttcg caccgacagc
     8461 atctgcgatt tcacggaatt ttgaaaaatc gataatttga gaataggctg aagcaccagc
     8521 tacaatcagt tttggtttta cttcttgggc ttgtttcaag atagcatcaa agtctaagag
     8581 ttccgtttta ggatcaacac tataagaaac aaagttgtag gtttgaccag agaagctaac
     8641 aggagcccca tgagtcaaat gaccacctga tgccaaatcc attcccataa ccgtatcacc
     8701 tggctcaatc aaggacatgt aagccgcaca gttagcttgg cttcctgaat gtggttgaac
     8761 attggcaaat ttagcaccga aaatttcttt tgcgcgttca atagcaagag tctctacaac
     8821 gtctactaca tcagttccac cataataacg gcgtcctggg taaccctcgg catatttatt
     8881 tgtcaagata gacccttgag ctgccataac agccttggaa actacgtttt ccgaagcaat
     8941 taactcgata ttattttgtt ggcgttcttc ttctttggca atagcattcc agagatcagc
     9001 atcatatgct ttaaaatcat ctttgtcaaa aatcataggt cttctccttt attgtgtgac
     9061 tagtccatta gtttgatttt acaataagaa aatcaaacta acagatgcga ataaaccgtt
     9121 tctgcatttt atcacaagta tagccaactt tttcataaaa tgcatgagca cccagacgat
     9181 gattggcaga atttaagcgg ataaacccat aaccacatct ttttgcttct tcttccaacc
     9241 cttgtagtaa acttttacca ataccttgac cttgcgcttg aggtgaaact gctaaagcta
     9301 agatattaaa tcctgctttg gaatagagtg attcgtaaac ttcagcgtgg acatatccaa
     9361 gtaagacatg attagctgca tcctcatagc caagtaggaa atgatgggaa tcctgagaca
     9421 gtctagctag ttggctagcc gtttcctctg gactaaaagt ataacccaaa gcctcttggt
     9481 tgatgtcaca tatcgctttc acatctgttt cttgcaaatc tcttagcatt tcaagcctcc
     9541 tcaaaagaaa tctctgacaa ccgagcaaga atatcttctc gtttaattgc gccttggcgt
     9601 aagattttca ccttgtctcc agacaaatcc acaatagttg aatcctgtcc agttagaaaa
     9661 gcatcgtctt ccagacccag aacctcttgg tcaaaatcct tcagaatttg ttcaaaggtt
     9721 acaccacttg cctgacctga gatattggca gacggcccaa tcaagggacc tgtctctcga
     9781 attaaatcca gtgtgatagg gtgactgggc atccgaaatc caatagttgc aaggtcagaa
     9841 tttacccaat agggaactcg gtcattggct tcgagaataa tggtcaaggg acctggcaaa
     9901 aaggtctcta caagtttttg tagataagct ggctgattct ttgaaaagtg caagatgtcc
     9961 tcgaaagagg cgatattgag attgagtgcc ttatctctag gacgacgttt gagttggtaa
    10021 acatggtcaa ctgctttttc atctaaggcc ttggaaaaaa gaccataaac agtctctgta
    10081 ggtagaacga cagctccacc cttttccaac tcttgtctaa tcctgtccat catcaaccac
    10141 aaccatccta ttttgaccaa attggtcttt gagtgttcga actctttttt caggaagatg
    10201 ttttctaaaa agttcgggaa cactttgacc ttgcttgtat ccaatttcaa ggtaaatctt
    10261 accaccatcc ttgagatagt cttttgcatc ttccgcaatt ctacagtaaa tagctaggcc
    10321 atcctcgtct gcaaagagag ctagatgagg ctccgaatgc aaaacattca agcctacctc
    10381 tgactcatct tcacgagaga tatagggtgg attggataca attatatcat atttttcaga
    10441 aatttctgca aaacaatcag attttttaaa aaatatatta agattttgat cgctagcatt
    10501 ctctgatgca agctctaagg cctcttgaga aacatctgct gctgtcactg accaatctgg
    10561 tctatttttt gctagagcga gagcaatagc tccactacct gttccaatat ccagaactga
    10621 gagattcgtc tcaagatttt cagttagaat aagctccact aactcctctg tttctggacg
    10681 aggaatcaaa acccgttcat ccacctttaa atgcattcca taaaaatctg cctgtccaat
    10741 gatgtactga gctggcttgt gagctgctag ttgctggtaa atatcttcta caaattgttt
    10801 ttcttcctct gttgtcacct cctgctggag ggcaaaaata aagtctgtaa aagatagatt
    10861 tttcagacta cgatagacaa aagagaggct ttccgcttcc tctccttgtc ttatcaactc
    10921 ttcttcaaaa tttgaaaata attgagctaa tttcattatt tgtttaattc ttctagtttt
    10981 tgtgtttggt cataaagcac caaggcatcc acaacttcgt ccaatttacc agacaaaatc
    11041 gtatctagtt tttggagggt caagccgata cggtggtctg tgacacggtt ttgtgggaag
    11101 ttataagttc ggatccgttc tgaacggtca ccagtaccga ttgtcgactt acgctcagcg
    11161 tcttgttcat cctgagcaat ctgagcaaag tggtcagcga cgcgtgcacg gataatcttc
    11221 atagccttct cgcggttctt ctgctgggta cgttcttcct gcatctcaac cttgatattg
    11281 gttggcaagt gaacgatacg aacggcagtc gcaaccttat tgacgttctg tccaccagca
    11341 ccagaggcgt gatagatgtc gacacgaagg tcttttggat caatgtcgta ttcaacctct
    11401 tcaacttctg gcataacaag aactgtcgct gtcgaagtat gaacacggcc ttggctttct
    11461 gtcacaggaa cacgttgcac acggtgggca cctgattcat acttaagctt agagtataca
    11521 gactgacctg aaaccatagc aaccacttct ttaaaaccac cgacaccatt catagaggct
    11581 tccatgactt caaagcgcca accttgggct tccgcatact tttggtacat agttagcaaa
    11641 tctccagcga aaagtgccgc ttcgtctcca ccagctgctc cacggatttc aaggatgata
    11701 ttcttgtcat cgtttggatc ctttggaagg agcaaaattt tcagtttttc ttcatattct
    11761 tctttttcag ccttggcatc tttgagttct tgcttggcca attcttccaa gtccgcatct
    11821 ccgcctgatt ccttaatcat ctcttcggca tcgacgatat tttgaaggac ttgtttatac
    11881 tcacggtagg ctattacggt gtcacgattg gaagcttctt cttttgaaag ctccataaaa
    11941 cgcttggtgt ctgaaacgac atcagggtca ctcagcaatt ctcctagttc ttcataacgg
    12001 tcttctacag cttgtagttg atcatagatg ttcatttttc ttcattctcc ttattgattt
    12061 caggggcaaa ataatgttta cggcaaaccg agatataggt ttcattacca ccaatctgga
    12121 tctgttctcc atcgtaaacg ggcagtccat cctgtgttcg caacaccatg gtcgcctttt
    12181 tcttgcaata ctgacagatg gtcttgattt cgtcaatctt gtccgctaaa agcaagagat
    12241 atttggaacc ttcgaacaat tcattgcgaa agtcattttt caagccaaaa gccatgacgg
    12301 gtatgtctaa ctcgtccaca acacgagcta ggtcataaac atggtggcgt ttgagaaact
    12361 gggcttcatc gaccaaaaca cagtaaggtt tttctggtag gtctcggata tagccaaaga
    12421 tatccgttgt ttcctcaatc gcaagggcag ggcgtttcat gccaattcga ctcgacacat
    12481 agccaacacc gtcacgcgta tccagagccg aggtcataat gacaacacct tttccttgct
    12541 cctcgtagtt ataggccact ttgagaatct caatcgtttt accagagttc atggtcccat
    12601 aacgatagta caactgtgcc atgtttcttg cttcacgtcc atttctaaat ttttgctaca
    12661 ttctagtata tcataatttt cttaagcttt aaacggcaaa atgtggtaaa atagaagaaa
    12721 tcaaaaacta gtggaggaag ctattatgcc atttgtacgc atcgatttat ttgaaggacg
    12781 cacgctcgag caaaagaaag ctcttgctaa ggaagtaacg gaagcggttg ttcgcaacac
    12841 tggagcacct caatctgctg tccatgtcat catcaacgac atgccagaag gaacttactt
    12901 cccacaaggg gaaatgcgta ccaaataagc tagcttaagc agaattgctt aggctttttc
    12961 aatctccaag tagcattcat tgaagaaata tcctaaattt gttacaattt gaaaagaaac
    13021 ttggagaatt tccaagaaaa gagcaattaa ttaaaggaaa cattatgatt acacgtgaat
    13081 ttgataccat cgctgctata tctactccac taggtgaagg ggctattggt attgtccgcc
    13141 tgagcggaac agacagtttt gctattgcgc aaaagatttt taaaggaaaa gacttgaaca
    13201 aggttgccag ccacactctc aactacggtc acattatcga tcctctgact ggtaaagtca
    13261 tggacgaggt tatggttggg gctatgaagt ctccaaagac cttcactcgt gaggatatta
    13321 tcgagattaa cacccacggt gggattgcgg tgaccaatga gattctccag ctagctatcc
    13381 gtgagggagc tcggttggca gaacctggtg aatttaccaa acgtgccttt ttaaacggtc
    13441 gcgtagattt gacacaggcc gaggcggtga tggatatcat ccgcgccaag acagacaagg
    13501 ccatgaacat tgcagttaag caattagacg gctccctttc tgacctcatt aacaataccc
    13561 gtcaagaaat cctcaataca cttgcccaag ttgaggtcaa tatcgattat cctgaatatg
    13621 atgatgttga ggaagctact actgccgttg tccgtgagaa gactatggag tttgagcaat
    13681 tgctaaccaa gctccttagg acagcccgtc gtggtaaaat ccttcgtgaa ggaatttcaa
    13741 cggctatcat tggacgtccc aacgttggga aatcaagcct tctcaacaac ctcttgcgtg
    13801 aggacaaggc tatcgtaaca gatatcgctg ggacaacacg agatgtcatc gaagagtacg
    13861 tcaacatcaa tggtgtacct ctcaaattga ttgatacagc cggtattcgt gaaacagatg
    13921 acatagtgga acaaatcggt gttgagcgtt cgaaaaaagc cctcaaggaa gccgacttgg
    13981 ttctactagt gctaaatgcc agtgaaccac tgactgcgca agacagacaa cttcttgaaa
    14041 ttagccaaga taccaatcgc attattctac ttaataaaac cgacctgcca gaaacgattg
    14101 aaacttcgaa actacctgaa gacgttatcc gtatttcagt ccttaaaaac caaaacatcg
    14161 acaagattga agagcgaatc aacaacctct tctttgaaaa tgctggcttg gtcgagcaag
    14221 atgctactta cttgtcaaac gcccgtcaca tttccctgat tgaaaaagca gttgaaagcc
    14281 tacaagccgt taatcaaggt cttgagctgg ggatgccagt tgatttgctt caagttgact
    14341 tgactcgtac ttgggaaatc ctcggagaaa tcactgggga tgctgctcca gatgaactca
    14401 tcacccaact ctttagccaa ttctgtttag gaaaataaga aaaatccatg atccttcatt
    14461 cggtcatgga ttttattgtc tttattagta atctggtctt aagacccctg ttacagttgc
    14521 cttagttgct tcgtagtcgc catctacgac aaccttgata atgcgtttgg catcttcttc
    14581 tggtgctgga acaagaggta gacgagtggg tccagcttca aatcccatat agttaagaac
    14641 tgccttaact ggagcaggac ttggataaga gaagagagca ttaaccttag gaatgaattt
    14701 acgctgaatt gctgcggctt tcttcatatc gctttctgca atggcagtaa acatctcgtg
    14761 catttcatcc ccatttgtat gagaggcaac agaaataacc ccatccgccc caaggttcat
    14821 ggcatggaaa gcatctccat cctcacctgt ataaatcaag aactcttcag gcttgtgctc
    14881 aatcaagtaa gccatattag ccaagctagt acattctttg acaccgataa tatttggatg
    14941 gtcagccaaa cgaagcatgg tttctggagt caattcgaca actacacgcc ctggaatgtt
    15001 atagataata attggtaggt cagaagcatc tgcaatagcc ttaaagtgct gatacatccc
    15061 ttcttgagaa ggtttgttgt agtaaggaac aatagcaagc ccagctgcga aaccaccaaa
    15121 ttccgctact tctttgacaa actcaataga gtcacgcgta tcattagtac ctacacccgc
    15181 aatcaaagga acgcgtccat tgacaacctt ttgtacagcc gcaaacaact ccaactcctc
    15241 atcgtgggtc aaagttggac tctcagcagt cgttcctgcg agaagaattc catccgtatg
    15301 atgggccaat aaatgctcaa tcaaggctgg aatagcatca aagttaatgg aaccatcctc
    15361 atggaagggg gtaataaagg ctgtaatgat tttacattct tttaaatctt gataagacac
    15421 gaaaacacct ctctatttca aagaaggagt tcatctgaac tcctaaacga tatgactatt
    15481 ttaattcaaa tttcaattcg gctgttggac gaaccaatcc acgttcatga agagtttcag
    15541 caatctgaac tgagttccaa gcagcacctt tgagaaggtt atctgaaaca acccacatgt
    15601 gaattccttt ttctgcatcc atgtctttac ggatacgacc aacaaaggta tcacgcgaac
    15661 caactgcatt gatagcttga ggatagattt gatgagctac atcatcttca agaacagcac
    15721 ctgggaaggc tgcgatagct gcttttactt cttcgattgg agccacctct tttgtttcga
    15781 tataaacaga ctcagagtga gctgacaaga ctggaatacg cacacatgtt gcagatactg
    15841 caatgctatc atcttccata attttcttag tttccttggt catcttcatc tcttcgtacg
    15901 tgtaatcatt atcagtgaaa acatcaattt gtggaagagc gttaaaggcg ataggataat
    15961 gtttcttgtc accacctgaa ggcaagattt ccgcatgcaa atcacgtggt ttcacaccat
    16021 cattcaagac ttcacgaagt tcacgttgtg tctcaagaat tgctcccata ccagcacctg
    16081 aaacggcttg ataagttgaa acaatgatac ggtccaagcc ccatttttgg cgaaccggct
    16141 caagagccac catcatttgg attgttgaac aattagggca ggcaatgatt ccgttgtgag
    16201 catcaagtgc atgagcattg acctctggaa caaccaaagg aacatctgga ttttgacgga
    16261 aataagatgt attatctact actaccacgc cagcttttac tgcgtatggt gcatacttag
    16321 ctgatgtaga actacctgct gaaaagagag caatatcaac tccttcaaaa gctgtttcag
    16381 tcgtttcttc aattgtaata tcttgatctt taaatttcaa tgacttacct gctgaacgtg
    16441 cagaagcaag gtaacggatt ttatcgattg gaagtgttga ttcttccaac atttttatca
    16501 tctgagcacc gacagcacct gtcgcgccga ctacagcaac tgtatatccc ataaataacc
    16561 tctttcggaa ttttctaaaa atttctataa tagaagtatt atactacttt ttccatgaat
    16621 tgcaaagctt tttcattatt ttttggaaaa taaaaatccc agtcgctaga ctagggacta
    16681 agaggcatct tcatgtgatg agcaggttca cacaactcat caaggtccgc tcctgcgtta
    16741 tgacctcctt atgctcaata gtagtccgaa gactacctat cgactcatcg catattctat
    16801 attactagag atacttgatt ttgtcaataa gaaatttttt cgatcgagta taacaaaaaa
    16861 ctcttgtatt caagagtttc cctatacata tcatgctaat tgccgggatt gaaccggcga
    16921 cctcatcctt accatggatg cgctctgcca actgagctaa atcagcttac ttaagaagta
    16981 tactataatc agaaaaactt gtcaagtttc cttagaaatt ttccatagga aaaagccagg
    17041 taagaactac ctagcttatc ttcttctatt tacttaaatc aattcgacga ccaattttac
    17101 caataataat cgctccaata atcaatgaag caaattcacc gattcctgtt gtaaaccaag
    17161 taaggaagaa tggtaattct gctacaatat ttaactctgc agcgatagta aacatggaaa
    17221 ttgaaaagag gattgaaaag aagaaatgat cttttcgaat caatccgtta aagaggtaat
    17281 ccttgctata ttttgcaaaa agccaaacac ctaaactgag gaatactaag gttgaaccac
    17341 caccaacaaa gacatctagc agtccgaagc taaagaaatt agcaatcata caaccgatgg
    17401 taactccgat gatgtactta ggattgtaaa aagccataaa gttcatcatt tctgaaatac
    17461 gaaactgata agcaccatag ctgatggcat ttaggggcgg tgtgacagtc aaaacgacgt
    17521 agatagcagc gacgattgca atatctgcaa catcacgaat agttaatttt ttcatctttt
    17581 ctcctttggc ggttatccgc gtgtaatatg cttggtgaaa gaagctaagc accaagggtt
    17641 gattcattca accttactag tatagcacaa tagcctgctt tatgctatac ttaaagcatg
    17701 aaaaaaccta ttcaaaaatt ttttaacaat gaaatcttag cctatctctt ttttggcctt
    17761 gcgacaactc tagtttcgat tctctcacga ctagtcattt atcaactaag tcatcaggaa
    17821 ctccttgcta cggccttggc aaatattatc ggtatcttat ttgcctttat cacaaatgat
    17881 acgattgtat ttaagcaaaa aaagaaaaat agacttatcc gtttagtgaa attttctctt
    17941 gctcgccttt ctacttttct gttagacttg tttttaactt ttctctttgt aacccaattt
    18001 cctcacatca tagggcaatt cgtaactgaa aacattgata agataaatgc tattgaaaca
    18061 ataattgcac aaatattcat tattatcatc aattatatct tgagcaaggt ctatattttt
    18121 agaaaataat gctccattta tgagcctttt aattgccttc tataatgatt taggatacaa
    18181 tgaaacacga aacattgaaa ggaaaacagt atgttaaaaa atctaaaatc gttcttgctt
    18241 cgaggaaatg ttattgacct tgctgtcggt gttgtcattg cctctgcttt tggtgctatc
    18301 gttacttcac ttgtaaacga cattatcact cctcttattt taaatcccgc tttgaaagct
    18361 gctaaagtcg aacgtatcgc tcaactttct tggcatggag tcggctatgg taacttttta
    18421 agtgctatta tcaattttat ctttgtaggt accgccctct tctttattat caagggcatt
    18481 gaaaaagcac agaaactgac tggcataaag aaagaaaaaa ctgccgaaaa aaaaccaacc
    18541 gaattggaag tccttcaaga aataaaagct ctccttgaga aaaaataatc gattaaaagg
    18601 atctagcgca aagctaaatc cttttttctt tactctttgg gtaacttgcc tgctttttca
    18661 agcatttttt tgataagata aggcatctta atattctccc gccctttttt ctcaatcagt
    18721 tttttcacaa attctggcat ttgtaaatct tcagattcag ctaaaatgtt tttcgtctcg
    18781 tctgaaggaa ctaactcatc aaaggtctct tcttctggga gaaattcctt aaactcttga
    18841 ttttcattga ctctaactgt attgaccaaa gcatcaatca aacgagaatc tgtatttggc
    18901 attggtggac gatggtagtt taccccaaat tcctgacata aatcataaca ttccacatca
    18961 ttgtcaaaca agacctcaat atgctcactg atgaaactaa taggtacaaa aatataatgg
    19021 tctggatgtt ctgtctgttc tctgagatac tccaaaacat ctggtttaat ccatggaata
    19081 ccaatatcac tctcactctg ccaagtgttg gtatattgtt ctgaactcaa gcccagtttt
    19141 tcagcgacta gcttgctatt ttcgaaaatt tggtctatat aaggatctcc aaagtccaag
    19201 gcaaaaatag gcacactatg ggctgaaaag atgactttaa agctgtcttg ctttacttct
    19261 tcttttaaaa tcttagcaat ttcatctgcc caatagttta agagcgcttc ttcctgatac
    19321 cagtccttaa tgaccaaaaa ttgaatttgt ttgctttcta aaaatttttc atagcccatg
    19381 acagagtaga aagaataatg gggctccaaa atcaagcaaa tacactgttc aattccgtct
    19441 gcttccattt gaccgatcac atctggaata aagggactgg aaaacttatt agcaaagtag
    19501 acactgtatt cattccccag cctagcttct accaaggcaa cctcttgacg ggtaattttt
    19561 tgcagaggcg tgcctccaat tcgtacataa ttatcataga gagtctgaat ctcgtggtct
    19621 tggggtctca tcccacgacg aatatttgtg aaaaaatcag ctacaccttc aaaggtaatc
    19681 tcttctggtg aaccgaaggt catcattaaa attgcttttt tcatgactgc ttccttgtga
    19741 tgtttttatc aagtttattt tatcattaat tcatcgataa gtaaacgcta gcatagggac
    19801 attctcaatc ttctgtcttt tgtttttctc ttctttctat gatacaatgg aaaaaataaa
    19861 ttcaaaagga gttttttatg acttatccaa atctcttgga ccgcttctta acctacgtta
    19921 aggtcaacac gcgctctgat gaacactcta ctactactcc aagtacacag agtcaggttg
    19981 acttcgcaac aaatgtccta attcctgaaa tgaaacgtgt tggactgcaa aatgtttact
    20041 atctaccgaa tggttttgct attggaacct tgccagccaa cgatccgtct ttaacacgta
    20101 agattggttt tatatcgcac atggatactg ctgattttaa tgctgaagga gtcaatccac
    20161 aggtaattga aaactacgat ggtggtgtga ttgaactagg gaattctggt ttcaaactcg
    20221 atccagctga cttcaagagt cttgaaaaat atccaggaca aacgctcatc acaacagatg
    20281 gaacaagctt gctaggcgct gatgacaaat caggaattgc tgaaattatg acagccattg
    20341 aatatctaac tgctcatcct gaaattaagc actgtgagat tcgtgttggt tttggtccag
    20401 atgaagaaat cggtgttggt gccaataaat ttgatgcaga agattttgat gtggattttg
    20461 cctacactgt tgatggtggt ccactaggtg aacttcagta cgagactttc tcagccgctg
    20521 gtgctgaatt gcatttccaa ggccgtaatg tccaccctgg tactgccaaa gggcagatgg
    20581 tcaatgccct tcagctagca attgattttc ataatcaact tccagaaaat gaccgacctg
    20641 agttaactga aggttaccaa ggtttttacc atctaatgga tgtgacaggt agtgttgagg
    20701 aggcgcgtgc aagctacatc attcgtgatt ttgaaaaaga tgcctttgaa gcgcgtaaag
    20761 catccatgca atctatcgct gataagatga atgaagaact tgggagcgac cgtgtcactc
    20821 tcaacttgac agaccagtac tacaatatga aagaagtcat tgaaaaagat atgactccaa
    20881 ttaccattgc taaagccgtt atggaagatc taggtatcac gcctattatc gaaccaatcc
    20941 ggggtggaac agacggctct aagatttcct ttatgggaat cccaactccg aatatctttg
    21001 caggtggcga aaatatgcac ggacgttttg aatacgttag ccttcagact atggaacgtg
    21061 cagttgatac catcattggc atcgtagctt ataaaggcta aaaagacgag gtagctcagc
    21121 tacttcgcct ttctttttat tctactggtt tttcttgatt tccagtagtt gtagaagatt
    21181 ctgttgtttt attttctgaa gttgattcag caggtttaga atctcttgta ttgcttggtt
    21241 tgttttcgtc gctagcagtt tcaatgttag attctgcagt tgcgtttggt tggttctcag
    21301 cactggtgtt atcaccattt gcttcagcat ttcttgctgg acttgtttct tcacttgcgc
    21361 tagcttttga ctggatttga tgattcaaaa ctagaatagc ttttgtcgat tcaagtaaag
    21421 ctgttttgtc tttactatta gcagaaagtt gatctaataa tgcatccacc ttatcaaaag
    21481 tccgcatcag atccattatt actttctaaa taaaagtgaa gcgacatgag aatatcgtag
    21541 agtttttgat agagtacaag tgtctgagga tcttgctcag cattttcctt ttcttgttga
    21601 agggcgctag cgatacgagt caagacatct tttacctgac tgtttacttc atccaagtct
    21661 gcatcagcct tgtttgtggc agcttttaga ttttctactt cttctgccaa agattgtctg
    21721 attccttctt catggattcg ttccaagagt tgatttgcct tgctcaaaag actttctact
    21781 tcttccttgc tatctgtcgc agattattgg ttgctatcta ccatgtactc ctaaaacagg
    21841 agagttataa tccaagatta caaggcctta cagaaataag aaatccagat aagacaatgt
    21901 tcgtccaaga cgctattcgc ttcgcacagc agcacggatt caatatgctt taattttaaa
    21961 gtttaggtgt caagacctct ttttagtgtg cccaaaattt agagaagtaa tcaatcaact
    22021 aacttttatt tttttcaaac tttcagtaaa ctgacctaaa gctaactcaa tctgtctttg
    22081 ttcgataggc ttgtctttgt agatgcttct gctatcagct agaagttgat ctacttttgc
    22141 caagactgcc ttctcatcaa aagttccagg ttgatagttg gattgcaggg atggaatctt
    22201 gtttttcaaa gccgcttcat atcccttagt ttgaaccttg atgtagtgat tgtggtcgcc
    22261 acgaggaatc acaaaacctt ctgaatcttc acttataatt cgattggcat caaaaccatg
    22321 accatcttct tcctcatggt ggacatgtag tgacggatta cttaatacag aactagaaga
    22381 acttcctacc tcttccgtgt tagagtgtga tgggggattg ttaagagatg acttaggaat
    22441 atagtgatag tgaccccatg tcttactata taagcatcac ctgtatctct gacaatatca
    22501 ttagggttaa agacataacc atcatctgct gcagaaacac cattattcgg tgtcaccgac
    22561 aaagattgac tgagagctgt agtattctct gataattata cttttgcagc tgctaattca
    22621 cctgccgaca agtcactctc aggaatgaaa tgatagtgac caccatgtgg tactatagta
    22681 gattgaaata gaatatgagc aaattgataa ggggatttta aagtaatttc taacaatgat
    22741 ttagaaacta tgatgtgcta ttctaaattc aactcactat atataaccat catcggtagt
    22801 ataacgtccc tgtaatttta ctacagatac ttctgcacta gctcctttat cgtctttacc
    22861 atgttcttgt ttttggcgat tgatttcatc ttttattcgt acattttctg catgagcttg
    22921 atctttaagg taaacataat actttccatc taccttaata atatatcctc ccttaaccta
    22981 actgacgata tcttgatctt tcggctgata gttgggggct ttcattaata gctcttcact
    23041 aaagagcgca tccaaaggaa ctttaccatt atagcagtga taatgatcgc catgagaagt
    23101 tacataacct tgatctgtaa tcttaataac aatttgtttt gcttgaattc cttctttttg
    23161 actaacctag tctggagtca aattttcagt cttcttagtg tctttattac tgtttacata
    23221 tgaaacacga tttttatctg tattggcctg ttagctatgt tggttcagag cataaacaca
    23281 cagacttaag gaaaggataa caacagatcc agctgctata tatttctttt taaatttcat
    23341 aattacctca t
//
LOCUS       DBEJKC010000029        22963 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.029, whole genome shotgun sequence.
ACCESSION   DBEJKC010000029 DBEJKC010000000
VERSION     DBEJKC010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22963
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.029"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..1340)
                     /locus_tag="ACL3G6_001224"
     CDS             complement(join(<1..899,899..1340))
                     /locus_tag="ACL3G6_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGR0545758.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSISLDYALPNQGMLSFWPAQYKKN
                     GYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENERLRTEVAYPKKVKRVRGKGRS
                     PRARKAETVREMVSGGFRLDFLLETARLARSTYYYQLKQLDGVDKDKEIKTEIQGIDN
                     EHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQ
                     VKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLESKEIQASMSRKGNSPDNGMME
                     SFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLSSVQYRTK"
     gene            complement(1433..2764)
                     /locus_tag="ACL3G6_001225"
     CDS             complement(1433..2764)
                     /locus_tag="ACL3G6_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HGR0545759.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLTDKE
                     ELVELLTRCAQNYQLRYEEFDYLASLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(2786..4297)
                     /locus_tag="ACL3G6_001226"
     CDS             complement(2786..4297)
                     /locus_tag="ACL3G6_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HGR0545760.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(4506..5453)
                     /gene="arcC"
                     /locus_tag="ACL3G6_001227"
     CDS             complement(4506..5453)
                     /gene="arcC"
                     /locus_tag="ACL3G6_001227"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HGR0545761.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(5618..6634)
                     /gene="argF"
                     /locus_tag="ACL3G6_001228"
     CDS             complement(5618..6634)
                     /gene="argF"
                     /locus_tag="ACL3G6_001228"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HGR0545762.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(6692..7921)
                     /gene="arcA"
                     /locus_tag="ACL3G6_001229"
     CDS             complement(6692..7921)
                     /gene="arcA"
                     /locus_tag="ACL3G6_001229"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HGR0545763.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            8677..10356
                     /locus_tag="ACL3G6_001230"
     CDS             8677..10356
                     /locus_tag="ACL3G6_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HGR0545764.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPAYG
                     NGGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGNCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKT
                     PRLSQTVAVQGLAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(10396..12480)
                     /locus_tag="ACL3G6_001231"
     CDS             complement(10396..12480)
                     /locus_tag="ACL3G6_001231"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HGR0545765.1"
                     /translation="MKPLLETIDTRLGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTGQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKASAQADWENLLHRFDVIETGEANRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLKTASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIANCAKKLKNIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKENKWLDIHTEQNHSHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            12651..13931
                     /locus_tag="ACL3G6_001232"
     CDS             12651..13931
                     /locus_tag="ACL3G6_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HGR0545766.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEKNWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETGQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFVELDLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            14022..16667
                     /locus_tag="ACL3G6_001233"
     CDS             14022..16667
                     /locus_tag="ACL3G6_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HGR0545767.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKVLHPTEGYKKMAALILPSYRVEDL
                     DGHPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            16751..17620
                     /locus_tag="ACL3G6_001234"
     CDS             16751..17620
                     /locus_tag="ACL3G6_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGR0545768.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILYKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQTCTYHADANLY
                     GALVNWLQEEKQW"
     gene            17614..19494
                     /locus_tag="ACL3G6_001235"
     CDS             17614..19494
                     /locus_tag="ACL3G6_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HGR0545769.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVTIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RHAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            19884..20210
                     /locus_tag="ACL3G6_001236"
     CDS             19884..20210
                     /locus_tag="ACL3G6_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545770.1"
                     /translation="MILWSFDFANDHAHAFFMDNVEWSHADSYFFSFVSDDVEERYTE
                     NVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSVGTSPEQYPDYDG
                     FDYEEW"
     gene            complement(20262..21104)
                     /locus_tag="ACL3G6_001237"
                     /pseudo
     CDS             complement(20262..21104)
                     /locus_tag="ACL3G6_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(21093..21242)
                     /locus_tag="ACL3G6_001238"
                     /pseudo
     CDS             complement(21093..21242)
                     /locus_tag="ACL3G6_001238"
                     /inference="COORDINATES: protein motif:HMM:NF016232.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            21577..>22963
                     /gene="pcpA"
                     /locus_tag="ACL3G6_001239"
     CDS             21577..>22963
                     /gene="pcpA"
                     /locus_tag="ACL3G6_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HGR0545771.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGV"
BASE COUNT         6660 a         4616 c         4969 g         6718 t
ORIGIN      
        1 tttagttctg tactgcacag aactaagtcc ttttagtttt accttaattc gtttgttgtt
       61 gtagtaatca atgtagtcca caatagcttg ttcaaggttt tctaaagatc taaagttctt
      121 ctcatagcca taaaacattt cggattttaa aatgccaaag aaagattcca tcatgccgtt
      181 gtctgggctg ttgcccttgc gtgacatgga tgcttgaatt tccttactct ctaggaaccg
      241 atgataagaa tcgtgttggt attgccagcc ttggtcacta tggagaatcg tattctcata
      301 gtatttctct gtaaaggcct gttctaacat actcttcact tgttctaagt ttggcgaagt
      361 agaaagatga taagcaatga tttcactgtt aaaaccatct aaaactggtg ataaatagag
      421 tttctgtgtg ctatttggaa tggcaaactc tgtcacatct gtatagcact tttccattgg
      481 cctcgatgct tcgaactggc gttgaatgag attctctgct ttcttgccaa tctctccttg
      541 gtaggaagaa tacttccgtt tacggcgaat tcgagccgtt aaaccaagaa ttctcatcaa
      601 ccgttgaact ttcttatgat tgaccacaaa accacgattc cttagttcta aatggattcg
      661 acgatagcca tagttgcctt tatgttcatt atcaatgccc tgaatttcgg ttttaatctc
      721 tttatcttta tcaaccccat ccagttgttt caactgataa tagtaagtcg agcgagctaa
      781 acgtgctgtt tcaagaagaa aatctagtcg aaatcctcct gaaaccattt ctctaactgt
      841 ctctgccttt ctcgctctag ggcttcgtcc ctttcctcta actcttttaa cttttttagg
      901 taggccacct cagtccgtaa gcgttcattc tcctcctgga gtcgttctag ttctgtcatt
      961 tcttcccaag tcttcttccg tttacgtccc attttagctg gtctccctct tgttttctca
     1021 acaatagtat acccgttttt cttgtattgt gccggccaaa atgaaagcat tccttggttt
     1081 gggagggcat aatcaagact aatacttctt tgtgaacaac cttccagtaa ggctttatcc
     1141 atcatttctt gtttcaattt agaagaatag tgacgattct tccctttttt aacgatttct
     1201 atgccataac ggtcaattaa tttcaccatg tactttagac cagaaacatc cacaccaaat
     1261 ctttttgaaa gctgtttgaa gctttgtcct tgctttctta gttcatagat ctgaacttta
     1321 tcttcataac tcaatttcat aataaaacac cccaaaagtt agatttattc tgtctaactt
     1381 ttggggtgca gttcattttg cgggattttt tttggtagaa acagttgcct gattaagttg
     1441 caagtcgata gacggcttcg gcataaatat ccatagcacg gtacaaatct tctagaacgg
     1501 cacattcatt tgcctgatgt tctgtctgct tcgctcctgg gaataaggcg ccgaaggcta
     1561 cacaatttgg catggtgcga gcaaaagtgg caccaccgga tgaaatagca ggactgttat
     1621 cgccagtctt ttcttggtag atttgcatca gtgtgctaac gagtttactg tcttttgcga
     1681 cgtatagaga cgctagatag tcaaactctt cgtagcggag ttggtagttt tgtgcacatc
     1741 ttgtaagcaa ctctactagt tcttccttat cagttaagac aggagtccga atgtcaatac
     1801 ggatttcaga acgttcatga ttgatcatga gacctgcgac attaaaggat aggtgaccag
     1861 aaggttcatc tgctatatca ccaaagattt gtcttcctgt gccgtcttga cctgcttgtg
     1921 ttgcaagaaa gctgagagca gggtgttctt ggagaggagc aagaatggta gctagtcgga
     1981 tgacagcatt gataccttga ctagcatcct tagcatgctt tggcactccg agaaccgtta
     2041 cggtttgttc agtggattgg taatcataac cagcttcttt gagatcgtta caaacctgtt
     2101 catagagggg accttggtag ttggccttgt ctggtacaac gttaaaggcg cctcctactt
     2161 caagctctag ttgatccgat ccagggccat gaagtttgac ctgtagaagc cctttttcag
     2221 cataggtcag aggaaaagat gagtcaggtg caaagcccat gctggcctgt tcttcgatgg
     2281 tattgtagcg tgccatgcag cgccagaggg tttcctcatc ggtaccaaag ataaagcgta
     2341 cgcgcttttt gaactgaata ccttggtcca gcaagctttt tactgcatag agagctgcga
     2401 gcgaagggcc tttatcatct tggacaccac gtccgaatac ccagccgtct ttgatagttg
     2461 cttcaaatgg cggtgtctgc caatctgctt catcacctga tggaacaaca tccaaatgac
     2521 agagaatggc cagaagctct gctccctgac cgatttctgc atatccgtaa taacctttag
     2581 ggtcaagata ggtagtgaaa cctatgtctc gacaaatctc taaagttttt tctaggacat
     2641 cttggattgc ttgtccaaaa ggtgttccat tttctccttc attgagtact gaaggatagg
     2701 aaatcaaggt ttttaatgat ataagaaatt catctttaac ttgatttgtt atatctattt
     2761 tcatggaatc acctcactca ctattttata ggaatggaag gaaggttcca aggagaagaa
     2821 gggcgatggt cactacaata atagcgacta cgagtttgcc catgaatttc caccaagtac
     2881 caatgttgat acgtccaagt gcaagagctc ccatcacaat accagatgtt ggtgcaatca
     2941 agttcaagac acctgaagca gattggtaag cagtgataat caagctagga cggacattta
     3001 caaattctcc aagtggagcc atgataccca tagttgcgct ggcaagacca gatgaagatg
     3061 ggatcaagaa tgacataggt agatagaaga tataagttac aacgataaag acttgtgaag
     3121 atagaccgct caagccttct ttaccccagt tgaggattgt atcggtaatc ataccgtcgt
     3181 tcatgataac ttgaatacca cgagcaatcg ctacgatcaa ggcaacactg agcaagtcag
     3241 cagcaccatt catgaaggaa gagataatct tatcttcttt aagaccataa ataacaccaa
     3301 tcaggatacc cataaaggca aagagcattg cgccttctgg gaagtaccaa gtacctagtg
     3361 cagaagtaga tgaaccgaca atattaccaa taactggaag accagtcaac caagcattaa
     3421 agtcatcaaa aatggtaacg ccaaggtctg tccatggaat gaagctcaat accatcaaga
     3481 tgaatgtcaa cacaaataag aagagaactg atttttgttt gctgctaagt gtagattcta
     3541 cagatgaaga ttcttctacg ttaaagtgtt tcaaatcttc tttgcgagta ctataaacca
     3601 gtgacttagt cggatctttt tgaatcttat ccgcataacg gtaaacaaac caagtactaa
     3661 gagcagtcaa ggtaacccag aagatcagac gaagtacgat accgtcccct gtaccaactc
     3721 ccgcagtcgc tgaagcaata cctgtcgcaa atggattcag agtagatgct aaacagccga
     3781 tttgagaacc gagcaaaata attgcaacac cagtcaggct atcaaaacca acggccatca
     3841 taactggcac aaggagtgga tagaaggcca ttgtttcttc acccatacca taagttgtac
     3901 caccgagggc aaacaaaggc atcagtacca aaattaacat tttttcgcgg cccttatact
     3961 tcttcacgat agaggcaatc cctacgtcaa gagcaccagt tttgttgaca atgccaagga
     4021 aaccaccaac cataaggatg aagaaggcta catcaatcgc tgcgctcgtt tctttaatga
     4081 gcgaaccttc ctctggatga gtacctagca tagcccgaat cggtgccatg aggacatccc
     4141 aaatcccttg tggattttga ggctgagtct cgtaaatacc ttctataaag gcccccgcag
     4201 ggataaacca agttagcact gccataatag caatgattat caataatacg gtgtaagatg
     4261 aaggcatctt aaaccctttt ttagcttttt cactcatttg tttttcctcc tgatgtctaa
     4321 caaagtgtaa aaaaccaact actttcttaa ataaacattc aagaaaacgc tttctattta
     4381 tatttgtttt accatattaa agtctaaaac tagtatcttt tgaaatattg tacatgtttt
     4441 caagaataat ttctaatttg atataaagat actagaaata gaatacatct tattagtaaa
     4501 acaacttatc ctttttcaat aattgttccg ctttcagatt caatcaaggc gcctagattt
     4561 tcaagggaag taataactgc ttttccttct ggacgaccat tgacaaaagc gatagctgct
     4621 tctacttttg gaagcatgct acctggtgca aactgatctt gtttgatata ttcttccagc
     4681 tgggcaacat tcacatgttc caatttttcc tggtttggct tgttgtagtt aacaaataca
     4741 taatctacac ctgtcaaaac gatgaagagg tctgcatcaa ccaattctgc caaacgttgg
     4801 gaagcgaagt ctttatcaat aaccgcttcg acaccagtca aatgtccatt gttttctttg
     4861 acgacgggaa taccgccacc acctgcagct acgacgactt gaccattatt taaaagagta
     4921 cggatggttt caatttcttt gatgtcaaca ggttttggtg aggcaacgac cttacgccag
     4981 ccacggccag catcttcctt gaaagtcgct ccgctctttt cggcttctgc ttttgcttct
     5041 tcttctgaat agaaaggacc gattggttta ctcaagttaa caaaagctgg atcattttta
     5101 tctacgacaa cttgcgttac aacagaggca acattttttt cgatgccttc atccaagaga
     5161 gcattttgca aagcattttt caaccagaaa ccgatgctac cttctgtcat agcgacaagt
     5221 gagtcgagtg ggaaggcagg gttcttttca gagtctgatg ccaaatgttg gagcaagaga
     5281 ttcccaactt gaggtccatt accgtgagtg ataatcagat catctccatt tttaatcaat
     5341 tttacaagat gcttagctgt ttcaactaaa gcttcttgtt gagcctttgc tgatgggtca
     5401 gaagaaagaa tcgcatttcc tcccaaagct actacaattt tacgatttgc cataaattct
     5461 cctttatcac actcaataga atgcgtttag atttcaattt aatgattttt cacatatttt
     5521 ataagaaata atagattacc attatataaa agaggaccgg actaaagcta ttagtcgcag
     5581 ccctcatagc tgttggtaga cggtttatta tctaaaatta tactttagga atataaaggt
     5641 taccaagtgt agcagccata acagctttga tagtgtgcat acggttttct gcttgatcga
     5701 agtggcgagc gtacttgctg cggaagactt cgtctgttac ttccatttct tctacaccaa
     5761 atttttcagc aacgtcttta ccataaacag tgtgagtatc gtggaatgct ggcaagcagt
     5821 gtaggaagat caagttttca ttgcctgctt ttttaactaa gtccatattg acttggtaag
     5881 gtttaagaag agctacacgt tctgcgaatt tgtcttcttc acccattgat acccaaacgt
     5941 ctgtgtaaag aacgtctgca tctttaactg cttcatcagc atcttcagtg atgagaacat
     6001 gtgcgccact ttctttagca aatccttctg ctaattcaac gatttctttt tctgggaaga
     6061 gttcttttgg tgagaagatg tgaacattga caccaaggat agcacctgtt acgagcaagc
     6121 tgttggcaac gttgttacgt ccatcaccac agtataccaa tgtcaagcct tccaagcgac
     6181 cgaagttttc ttgaacagtc aagtagtcag cgagcatttg agttgggtgc cattcgtcag
     6241 ttagaccgtt ccatactgga acgcctgaga attctgccaa ttcttcaacc atacgttggc
     6301 tgaatccgcg gaattcaatc ccgtcaaaca tacgtcccaa tactttagca gtatcttcag
     6361 tagattcttt tttacccaac tgaatatcat ttgctccgag gtattctggg tgagcaccaa
     6421 ggtcgatagc cgcagttgta aaggctgcac gagtacgagt agatgttttt tcaaatagga
     6481 gagcgatatt cttgccagca aggtagtggt gttgaatatt gcgttttttc aaatctttca
     6541 agtgagctga aagaccaata aggtattcta actctgcacg ggtaaagtct ttttctgcta
     6601 agaagctgcg tccttggaat actgaatttg tcattttatt atttcctctt tctatttttt
     6661 acattttcta ttgacgaatg ccgaacagcg attacacttc ttcacgttca aatggcatag
     6721 acatacaacg aggtccacca cggccccgaa ccaattcact tccgcgaatc ttaatcaagc
     6781 gaagcccgta ttcttccaaa atcttattgg tcacggtatt gcggtcataa acaactacca
     6841 caccaggtgc gatggtcaaa gtgttagaac cgtcgttcca ttgttcacgc gcagctgcta
     6901 cgatattgcc accaccgcaa cgaatcaaat gaactttttc tacaccaagg ttttgagcaa
     6961 gaagttcagc taagtcacct ttctcttcaa cgattttaag tttttcgttt tcgtaagtaa
     7021 ctgagtaaac gtgaaggtcg ccttcgattt ctgggtgaat agtgaacttg tcatagtcta
     7081 ccatagtgaa gacagtatcc aagtgcatga atttacggtt gttagcaaat tcaaaggcca
     7141 aaactttctt gaagccaaca tttttcttga agatgttgac caaaagtttt tcgatagaag
     7201 ctgcgtctgt acgttgagag atacctactg caaggacgtc tttagaaaga actaactcgt
     7261 ctccaccttc gatacgcgta tcttcttcac ggttgtagac caaatccact tttccgccat
     7321 agattgggtg gtatttgaag atatacttac cgtagagtgt ttcacggtta cgagtgtctg
     7381 caaacatgtg gttaagcgat acggcgtttc caattgttgc aaatgggtcg cgagtgaaat
     7441 agaggtttgg catcgggtca attgcaaatg gataatctga ttcaactaag tcagttagat
     7501 ctttagcttc gtcaggaatt tctggcaatt caactttttg aatcccagcc attgtttttt
     7561 caaccaattc ttggttgtcc ttgatgccgt gaagcaattc acgaatagca accttggttt
     7621 gacgatcacg gatgttggct tcgtctaagt attcctcgat aaattgatcg cggatttctg
     7681 gagaggtcaa tgattcagca gcgagttgtt ctaggtagag aacctcaatt ccttcatcgc
     7741 gaagagcttg ggcaaatgca tcatgttctt tttgagcatc ttccaagaaa ggaatatcat
     7801 caaaaagaag cctttcaaga tagtccggca acaagttttc taactccttg cctggacggt
     7861 gcaacataac ttttttcagt ttcccaattt ctgagaagac ctgaattgga tgtgaagaca
     7921 tgtattttcc tccttaaaaa ttttgacttg gcaccatttt gggtaccgct tacatgtatg
     7981 ttataacgca attcctaggt aatgtcaatg gctataattt ctcggaaaat aatataaatt
     8041 atgatgttta gcacaatttt atgttattat acataacata ggatagaata catagataca
     8101 aatgcataaa cttctattaa agaggatata aaattttttt aaaaaatttt tcaaaaaata
     8161 cacaaataac caaaaagtgt ccaattatca tctggttatc acttggatct gtataaagag
     8221 aaatgtttgt gtgaaaggat aaaaagatgc aacattcttt tgaagataga ttttggagaa
     8281 gcatttcttg ttcaattgta caaattatag aatcttttct gagtatttag gaagagataa
     8341 ttatcttatt gaccctcttt ttattttttg ttatagtcga cgagatgata gtttagaata
     8401 atcacttatt cacaatctgt ggaaaagtct ggagagtgaa tggtcttcac acaatgacct
     8461 gaaagaagcc tgagaataat tatggagagt agcattctga gaggtgttag cagaaccata
     8521 tgacagagct gtttgaagag ggaatattga ggagaaaaat cctgagccta ccagttggag
     8581 ttggaaagag ctggcggtta gatcattttt tattatccac aacctgtgga taaccttgtg
     8641 aacaagagaa gttgctaaag aaggagatat ataacgatga agaaaatcaa accgcatgga
     8701 ccgttaccaa gtcagactca gctagcttat ctgggagatg aactagcagc ttttatccac
     8761 ttcggtccta atacctttta tgaccaagaa tgggggactg gacaggagga tcctgagcgc
     8821 tttaacccga gtcagttgga tgcgcgtgag tgggttcgtg tgctcaagga aacgggcttc
     8881 aaaaagttga ttttggtggt caagcaccac gatggctttg tcctttatcc gacagctcac
     8941 acagattatt cggttaaggt cagtccttgg aggagaggaa agggcgactt gctccttgaa
     9001 gtatcccaag ctgccacaga gtttgatatg gatatggggg tctacctgtc accgtgggat
     9061 gcccatagtc ccctctatca tgtggaccga gaagcggact acaatgccta ttatctggct
     9121 cagctgaagg aaatcttatc aaatcctgcc tatggaaatg gagggaaatt tgctgaggtt
     9181 tggatggatg gtgccagagg agagggcgcg caaaaggtta attatgaatt tgaaaaatgg
     9241 tttgaaacca ttcgtgacct gcagggcaat tgcttgattt tttcaacaga aggcaccagt
     9301 atccgatgga ttggcaatga acgagggtat gcaggtgatc cactgtggca aaaggtgaat
     9361 cctgataaac taggaacaga agcagagctg gactatcttc agcacgggga tccctcgggc
     9421 acgatttttt caatcggaga ggcagatgtt tccatccgtc caggctggtt ctaccatgag
     9481 gatcaggatc ctaagtctct cgaggagttg gtcgaaatct actttcactc agtagggcga
     9541 ggaactccac tcttgcttaa tattccgccg aatcaagctg ggctctttga tgcaaaggat
     9601 attgaacgac tttatgaatt tgcgacctat cgcaatgagc tctataaaga agatttggct
     9661 ctgggagctg aggtatctgg tccagctctt tccgcagact ttgcttgtcg ccatttgaca
     9721 gacggccttg agaccagctc ttgggcaagc gatgcagact tgcccatcca gttagaactc
     9781 gacttaggtt ctcctaaaac ttttgatgta attgagttga gagaagattt gaagttaggc
     9841 caacgtattt ctgctttcca tgtgcaagta gaggtggatg gtgtctggca ggaatttggc
     9901 aggggcttca cagttggtca taagcgcctc ttgcgaggag cagttgttga agcacagaag
     9961 atacgtgtag tcattacaga atcacaggct ttgcctttgt tgaccaagat ttcactctat
    10021 aaaactccga ggttatcaca aacagtagct gttcaggggc tagcatttgc agaaaaaagc
    10081 ctagctgtgg caaagggaga gactcttcat tttaggattg aacgtagtga aagtagctcc
    10141 tctttagagg ctaagatttc gattcaaccg gggacaggtg tccatggtgt cgcctatcag
    10201 gatgagattc aagtccttca attccaagca ggggaaagca aaaaagattt gcatctacca
    10261 accctgtatt tcgcaggaga taaaaccttg gatttctatc tgaacctaac ggtggatggt
    10321 cagcttgtgg atcaacttca agtccaagtt tcataaaaga agaacctttg cgcgatgcaa
    10381 aggttctttt ggttattagt gatttggtag ccagctgagg gtgaaagtta gttgttcagc
    10441 ttttaggagg tcttggtgtt gaatagttga tacgagtgtt ttgtccagtc ggcattcttt
    10501 gacaaagtta aaatggctgt ggttttgctc agtatgaata tctagccatt tattttcttt
    10561 agctaggtag actcgtagat ggtcaaagag aggaattccg agatcatagc ttggttttcc
    10621 tggacaggtt ggataaaatc cgagagctga ccagatgtac caagcagaga gactaccatt
    10681 gtcttcatct ccaggatagg cttcccaact tgggtgaaaa gctttctgac ggagcgtctt
    10741 gataagaagg gcagtgtagt cagggtaatc gctgtagcgg aagagataag gaatgtggaa
    10801 actaggctgg ttggaaatgg ctatttgtcc aaaaggagca gtagccatct cgctcatttc
    10861 gtgaatttcg taaccatagc ctgttgtttc aaagagggga gcatcttgac aggctttcaa
    10921 aagatagttg ctaaaggttt cttttccacc catcagttgg attaagccag ggatgtcgtg
    10981 gagaacgcct aaagtagctt gaatggcaga gcattcagcg tagtctcgcc cccaactata
    11041 aggagagaag tcagggtgaa agtttccttg attgtctcgt gctcgcatgt aacctgtctc
    11101 agcgtcaaat agctggcggt aattttgtga agcagccttg taggtttcag cgatttctat
    11161 gttttttagt tttttggcac agttggcgat acaaaagtca ctataggcat agtctagagt
    11221 atggctaaca ctttcgtggt ggtcggtaga gaggtaacct agttcttggt attgggctag
    11281 tccgtggcgg ccattgatgc cgagagggtc ggctttgctg gctgttttga gcatggcttg
    11341 gaagagttct ccttctaggt cgggggccat gtccttgcag gcgctatctg cgataatacc
    11401 gtctaaaagt gtacctggca tcataccccg ttcatctgga gccagccatt ttggaaggaa
    11461 accagtatcg cggtagctat tgaggaaacc ttctaaaaag cgttgatagt gctccggtat
    11521 gataagggca aagaggggga aggtggtgcg gaaggtatcc cagaaaccat tgttgctaaa
    11581 gaggacacca ggcttgacag taccagtagc cagatccatg tggatggctt gccctgactc
    11641 atcaacctca taaaaagtct gtgggaagag gaagagtctg tagagacagt ggtcaaagaa
    11701 ggttcggtta gcctctcctg tctctataac atcaaaacga tggaggagat tttcccaatc
    11761 cgcttgggca cttgctttac agctatcaaa atcttcttga ggtagattga ttagagcttg
    11821 agaaggagag atgaaagaag tggctagttg catctcggtt tgactacttg ctaagtcaat
    11881 tcgccagtct ccagcttctt ggctgatagc aagaatatcc gtgttcattt gcagggcagt
    11941 gaacatcgtt agcgaatttt tgttggtttc agttttacct tcttgtcgca gggcaagagt
    12001 tcgcttatct acttgctcta ctgtcagttc atctgctgcg tgaagataga gggagagggc
    12061 tttgccttgc ttttgcttca aacgaataga agcaccgtag caagtcggtg tgagctgggt
    12121 ttcaatttga tagcgcaggg agaaaatctt tagataatga ggttggaaag aggccttatc
    12181 cctatcatag gaagattggc ggtgaaagag actgtctccc ccaagctgac ctgtgacagg
    12241 tgtcagaagg agccaagagt agtccccaat ccaaggactg ggctggtgag ttaatcgaat
    12301 cccctgaaag ataggcagat gcggatcgaa gaaccaagat ccatcctggt cactggtctg
    12361 gggcacaaag taattcatcc caaaaggcac gcctgtgtat ggcagggtat ttccccgaga
    12421 aaaggcatgc ttgttggtag ttcccaagcg ggtatcgatg gtttcaagta gtggtttcat
    12481 agtctttcct ttagctgttt ttctacatta tatcagaaaa agagggcctt tagaaaagga
    12541 gtttcaaaga taactatttt gtagaaaaat gactatcatt tgtgtatgta ttttctgtct
    12601 caaaagctat atactgaaaa tgaaacttgt ttgaaagagg gaattgcacg atgatttatt
    12661 cgaaagaaat tgttagagaa tggctagatg aagtagcaga gcgggctaag gaccatccag
    12721 agtgggtgga tgttttcgag cgttgctaca ccgatacctt ggacaatacg gttgaaatct
    12781 tagaagatgg ttcaactttt gtcttgactg gggatattcc tgccatgtgg cttcgagatt
    12841 cgacagccca actcagaccc taccttcatg tagctaaaag agatgccctc ctgcgtcaga
    12901 ccattgcagg tttggtcaaa cgtcagatga ccttggtact caaggatccc tatgctaact
    12961 ccttcaacat tgagaagaac tggaaagggc accacgagac tgaccacaca gaccttaacg
    13021 gctggatctg ggagcgcaag tatgaggtgg attcactttg ctatcctttg cagttggctt
    13081 atctcctctg gaaagagact ggcgagactg gtcagtttga tgagactttt gtcgcagcga
    13141 ctaaggaaat tctccatcta tggacagttg aacaagacca caagaactct ccttatcgtt
    13201 ttgtccgaga tacggaccgt aaggaagaca ccttggtaaa tgatggcttt ggacctgact
    13261 ttgcagtgac aggtatgact tggtcagctt ttcgtccgag tgacgattgc tgtcagtata
    13321 gttacttgat tccgtctaat atgtttgccg tagtagtctt gggttatgtg caagaaatct
    13381 ttgtcgaatt agacctagct gatagccaga gtgttattgc tgatgccaag cgtcttcagg
    13441 atgaaatcca agaaggaatc gaaaactacg cttacaccac caacagcaag ggcgaaaaga
    13501 tttacgcttt tgaagtagat ggcctaggaa atgccagcat catggatgat ccaaatgtac
    13561 caagtctact agctgcgccc tatctgggct actgttcgat cgatgatgaa gtgtatcaag
    13621 ccactcgccg taccattctg agctctgaaa atccatactt ctaccaagga gaatacgcta
    13681 gcggtctcgg aagttctcat accttctatc gctatatctg gccaatcgcc ctttctatcc
    13741 aaggattgac aacaagagat aaggcagaga aaaaattctt gctggatcag ctggttgcct
    13801 gcgatggtgg tacaggtgtc atgcacgaaa gcttccacgt agatgatccg accctctact
    13861 ctcgtgaatg gttctcctgg gctaacatga tgttctgtga gttggtcttg gattacttgg
    13921 atattcgcta aggggctcgc tttagctcaa ccgattctta tcagaatcac aagtttacat
    13981 ttaaaacgtt aaaatttaaa tttagaatga ggttttactt catggaaaat gttgttgtac
    14041 atattatctc acatagtcac tgggaccgtg agtggtactt gccttttgaa agccatcgta
    14101 tgcagttggt ggaattgttt gacaatctct ttgatctctt tgaaaatgac cctgagttca
    14161 agagtttcca cttggatgga caaactattg tccttgatga ctacttacaa attcgccctg
    14221 aaaatcgcga caaggtccaa cgctacattg acgagggcaa acttaaaatt ggtccctttt
    14281 acatcttgca ggatgactac ttgatctcca gtgaagccaa tgtccgcaat accttgattg
    14341 gtcaacaaga agctgccaaa tggggtaaat caacccagat tggctacttt ccagatacct
    14401 ttggaaatat gggacaagcg cctcaaattc ttcaaaaatc aggcattcac gtggcggcct
    14461 ttggtcgtgg tgtgaagccg attggatttg acaaccaagt ccttgaagat gagcagttta
    14521 catcccagtt ttcagaaatg tactggcagg gtgtggatgg tagtcgtgtt ttaggtattc
    14581 tctttgccaa ctggtacagt aatgggaatg aaatcccagt tgacaaagat gaggccttga
    14641 ccttctggaa acaaaaattg tcagatgtgc gtgcctacgc ttcgaccaac caatggttga
    14701 tgatgaacgg ctgtgaccac cagcctgtac agaaaaatct gagcgaagcc attcgtgtgg
    14761 caaatgaact cttcccggat gtaatctttg ttcatagttc ttttgatgaa tatgttcaag
    14821 ctgtagaagg tgcgcttcct gaacacttat caactgttac aggcgagttg accagtcagg
    14881 aaacagatgg ctggtacaca cttgccaaca cttcttcatc ccgcatttac ctaaaacaag
    14941 ccttccaaga aaatagcaac ctcctagagc aagtggtaga acccttgact attatcactg
    15001 gtggacacaa ccacaaggac cagttgacct atgcttggaa aacacttttg cagaatgcgc
    15061 cacatgatag tatctgtggc tgtagcgtgg acgaagttca ccgcgagatg gaaacgcgtt
    15121 ttgccaaggt caaccaagta ggaaactttg ttaaaagtaa cttgctcaac gagtggaagg
    15181 gtaaaattgc tacggataag gctcaaagtg actatctctt tactgtcatt aacacaggct
    15241 tgcatgataa ggtcgatact gtcagcacag tgattgatgt ggcgacttgt gatttcaagg
    15301 tattgcaccc aacagaaggc tacaaaaaga tggctgctct tatcttgcca agttaccgtg
    15361 tggaggactt ggatggtcat cctgtagagg ctacaatcga agacctcgga gctaattttg
    15421 agtatgattt accaaaagac aagttccgcc aagctcgtat tgctcgtcaa gtgcgcgtga
    15481 ccattccagt tcacctagcg ccgctttctt ggacaacctt ccaattgctg gaaggaaaac
    15541 aagaacaccg tgagggtatt taccaaaacg gagtgattga tacaccattc gtaacggtga
    15601 gtgtggatga caacatcaca gtctatgaca agacaactca cgaagcctat gaagacttta
    15661 tccgctttga agaccgtggg gacatcggaa acgagtatat ctatttccaa ccaaaaggaa
    15721 cagagccaat ctttgcagaa cttaagggcc acgaggtctt ggaaaacaca gcttgctatg
    15781 ctaaaatctt gctcaaacat gaattgaccg tgcctgtcag cgcggatgaa aagctagaag
    15841 aagagcaaca aggtatcatc gagtttatga agcgtgaggc tggacggtca gaagaattga
    15901 caaacattcc tctggaaact gagttgactg tcttcgttga caatccacaa atccgcttca
    15961 agactcgctt tactaacact gccaaggatc accgtatccg tctcttggtc aagactcata
    16021 acacgcgtcc aagcaatgat tctgaaagta tctatgaggt ggtgacacga ccaaacaaac
    16081 cagctgcttc atgggaaaat cctgaaaatc ctcaacacca acaagctttt gtcagtctgt
    16141 atgacgatga aaaaggggtg actgtatcca ataagggatt gaatgaatac gaaatccttg
    16201 gggataacac cattgccgtg accattttgc gtgcatcagg tgagctaggt gactggggct
    16261 acttcccaac gccagaagca caatgcttgc gtgagtttga agtcgagttt gcacttgaat
    16321 gccaccaagc ccaagaacgc ttctcagcct atcgtcgtgc caaagccttg cagacaccgt
    16381 ttaccagcct tcagcttgct agacaggaag gaagcgtggt tgcgactggt agcctcttga
    16441 gccattctgt tctcagcata ccgcaagttt gtccaacagc ctttaaagtg gcggaaaatg
    16501 aagaaggcta tgtcctccgt tactataata tgagtcaaga aaatgtgcgc atatcagaac
    16561 atcaacaaac cattcttgac ttacttgagc gaccatatcc agttcattca ggactattgg
    16621 ctccacaaga gattcgtaca gaattcatca aaaaagaaga aatttaattt caaaaagtaa
    16681 acatcaaaag aaaggagggg cgaaaaagta agaactaact gctgattcgc ccctttttat
    16741 ggtaaaaaca atgaccattg caacgattga tatcggaggg actgggatta agtttgccag
    16801 tctgactcct gatgggaaaa tactgtataa gacaagtatt tcaacgcctg aaaacttgga
    16861 ggatttacta gcgtggctag atcaacgctt gtcagaacag gattacagtg ggattgctat
    16921 gagcgttcca ggtgcggtca atcaagagac aggtgtgatt gatggcttca gtgcggtgcc
    16981 ctacatccat ggcttttctt ggtatgaggc gcttagctct tatcagctac ctgtccattt
    17041 agaaaatgat gccaactgcg ttggactcag tgaactacta gctcatccag agcttgaaaa
    17101 tgcagcctgt gtcgtgattg ggacagggat tggcggagcc atgattatca atggtagact
    17161 tcatcgaggt cgccacggtc tgggtggaga atttggctac atgacaaccc ttgcccctgc
    17221 tgaaaaactt aataactggt cgcaactagc atcaactggg aatatggtac gatacgtgat
    17281 tgaaaaatct ggtcatactg attgggacgg tcgcaagatt taccaagagg ccgcagctgg
    17341 taatgctctt tgtcaagaag ccattgagcg catgaaccgc aatctgacgc aaggcttgct
    17401 caatatccag tatctgatcg atccagatgt catcagtctg ggtggctcta tcagtcaaaa
    17461 tccagatttt atccaaggtg ttaagaaggc tgttgaagac tttgtcgatg cctacgaaga
    17521 atacacggtc gcaccagtta tccagacctg cacctatcac gcagatgcca atctctacgg
    17581 tgcccttgtc aactggctac aggaggaaaa gcaatggtaa gatttacagg acttagtccc
    17641 aaacaaacgc aagctattga ggttttaaaa ggtcatattt ctctaccaga tgtggaagtg
    17701 gctgtcactc agtctgacca agcctctatc tctatcgagg gtgaggaagg tcactatcaa
    17761 ttgacctacc gcaaacctca ccaactttat cgtgccttat ccttgttggt aacagttcta
    17821 gcagaagctg ataaagtaga gattgaggaa caagcagctt acgaagattt ggcttacatg
    17881 gttgactgtt ctcgaaatgc ggtgctgaat gtggcttctg ccaagcagat gattgaggtc
    17941 ttggctctca tgggctactc aacctttgag ctttacatgg aagacactta ccagattgaa
    18001 ggacagcctt actttggcta tttccgtgga gcttattcag cagaggagtt gcaggaaatc
    18061 gaagcctatg cccaacagtt tgacatgacc tttgtaccat gcatccagac cttggcccac
    18121 ttgtcggcct ttgtcaaatg gggtgtcaag gaagtccagg agctccgtga tgtagaggac
    18181 attcttctca ttggcgaaga aaaggtttat gacctgattg atggcatgtt tgccacgttg
    18241 tctaaactga agactcgcaa ggtcaatatc gggatggacg aagcccactt ggttggtttg
    18301 ggacgctacc tgattttgaa cggtgttgtg gatcgtagtc tcctcatgtg ccaacacttg
    18361 gagcgcgtgc tggatattgc tgacaaatat ggtttccact gccagatgtg gagtgatatg
    18421 ttcttcaaac tcatgtcagc ggatggccag tacgaccgtg atgtggaaat tccagaggaa
    18481 actcgtgtct acctagaccg tctcaaagac cgtgtgactc tggtttactg ggattattat
    18541 caggatagcg aggaaaaata caaccgtaat ttccgcaatc atcacaagat tagccatgac
    18601 cttgcatttg cagggggagc ttggaagtgg attggcttta cacctcacaa ccattttagc
    18661 cgtctagtga ctatcgaggc taataaagcc tgccgtgcca atcagattaa agaagtcatc
    18721 gtaactggtt ggggagacaa tggtggtgaa actgcccagt tctctatcct accaagcttg
    18781 caaatctggg cagaactcag ctatcgcaat gacctagata gtttgtctgc gcacttcaag
    18841 accaatactg gtctaacggt tgaggatttt atgcagattg atcttgccaa cctcttacca
    18901 gacctaccag gcaatctcag cggtatcaat cccaaccgct atgtttttta tcaggatatt
    18961 ctttgtccga ttcttgatca acacatgaca cctgaacagg acaaaccgca cttcgctcag
    19021 gctgctgaga cgcttgctaa cattaaagaa aaagctggaa actatgctta tctctttgaa
    19081 actcaggccc agttgaatgc tattttaagt agcaaagtag atgtgggacg acgcattcgt
    19141 catgcctacc aagcggatga taaagaaagt ttacaacaaa tcgccagaca agaattacca
    19201 gaacttagaa gccaaattga agacttccat gccctcttta gccaccaatg gctgaaagaa
    19261 aacaaggtct ttggtttgga tacagttgac atccgtatgg gcggactctt gcaacgcatc
    19321 aaacgagcag aaagccgtat cgaggtttat ctggctggtc agcttgaccg catcgacgag
    19381 ctggaagttg aaatcctacc atttactgac ttctacgcag acaaggactt cgcagcaact
    19441 acagctaacc agtggcatac cattgcgaca gcgtcgacga tttatacgac ttaatactct
    19501 tcgaaaatct cttcaaacca cgtcagcttc catctacaac ctcaaaacag tgttttgagc
    19561 agcctgcagc tagcttccta gtttgctctt tgattttcat tgagtataaa aacaagaaca
    19621 ccttgcttgg cgcagggtgt ttcgcgtgaa acagaagaat tatctggttt caaatgctac
    19681 agttagacaa acttatgata aaatagcaga aagtgaatgt ttcctaagag caattctatc
    19741 gatgagcaat tggaggtatt atgctacact taaaattagt aaaacaagaa atagaagctt
    19801 gggtcatttc cgtcaaattt aaaaaaggtt gctaccgaca tatatagatt ccaaaaacaa
    19861 aaacgttagc gaaactagca gatgtgattt tatggagttt tgattttgca aatgatcatg
    19921 ctcacgcatt tttcatggat aatgttgagt ggagtcatgc agattcttac ttttttagct
    19981 ttgttagtga cgatgttgaa gaacgttaca cagaaaatgt ctatctggat agcctaagtg
    20041 tcaaacaaaa atttaagttt attttcgact tcggtgatga atggcgtttt gaatgccaag
    20101 tgctgagaga aatcgagaca gaggacgaag aagcttatct cgtacgttcg gttggaacgt
    20161 cgccagaaca atatccagat tatgatggtt ttgactatga agaatggtaa aattgaaatc
    20221 agtctgtgta ggcttagtat ttcaatagac ttcctgcaaa actagaatcc tagttcatga
    20281 ttgataatac cagcactcaa attcattcgt aatccgaagc gtttacgatg atttcgatag
    20341 gttgttgaaa ttattttaaa cgtttttact ttggcaaaga tgttctcaac cttgcttctc
    20401 tccttggata gcgcatggtt acaggcttta tcttcaactg ttagcggctt gagtttgctg
    20461 gatttacgtg gagtttgtgc ttgaggatat atcttcatga gcccttgata accactgtca
    20521 gccaagattt taccagcttg tccgatattt ctgcaactca ttttgaacaa cttcatatca
    20581 tgacaatagt tcacagtgat atccaaagaa acaattctcc cttgacttgt gacaatcgct
    20641 tgagccttca tagcgtgaaa tttcttttta ccagaatcat tcgctaattg tttttttagg
    20701 gcgattgatt tttacttccg tcgcatcaat cattaccgtg tcctcagaac tgagaggagt
    20761 tcttgaaacc gtaaaaccac tttgaacaag agttacttca acccattggc tccgacggat
    20821 aaagttgctt tcgtgaatac caaaatcagc cgcaatttct tcataagttc gatattctcg
    20881 cactattgaa gagtgggcat aagaaggtct tctaggctta atttaggttt tcgtccacct
    20941 tttgcgtgtt taagttgata agctgttttt aatacagcta acatctcttc aaaagtcgtg
    21001 cgttgaacac caacaagacg cttaaatcgt gcatcggtta gttgtttact tgcttcataa
    21061 ttttgtttcg cagggagtct attgactctt tggtaggtgt caatgttttt ttcatctatc
    21121 ccgagaatta ttttcccgcc atttgtattt gcaaatgctg agtaggtttc ccagaaagac
    21181 tctggaagat tgtttttagc ttttttgtat tctaaatcaa ccccttcaaa ttttaagtcc
    21241 atatttttcc tttacatctg ttttttgtgg ttctggtatt tgttcaagtt gagtgataat
    21301 atagcgaatt gaatttcgag agtttttact cagttaattt cttttttaac ccactttaat
    21361 ttctttttta acacgggtta aaaaagaaat taaagtgggt taattttcct tgacttaaaa
    21421 tttaaaaatg atatactgtg tttatggaga gatgacaatt tataaaatgt actactctat
    21481 tctactagat aatgattgaa taaaactttt tataacaacg gctagcaaag ttataatttt
    21541 atatctatta gaaaataaat atgtaaggaa atttaaatga aaaaaactac aatattatca
    21601 ttaactacag ctgcggttat tttagcagca tatgtcccta atgaaccaat cctagcagat
    21661 actcctagtt cggaagtaat caaagagact aaagttggaa gtattattca acaaaataat
    21721 atcaaatata aggttctaac tgtagaaggt aacataggaa ctgttcaagt gggtaatgga
    21781 gttactcctg tagagtttga agctggtcaa gatggaaaac cattcacgat tcctacaaaa
    21841 atcacagtag gtgataaagt atttaccgtt actgaagtag ctagtcaagc ttttagttat
    21901 tatccagatg aaacaggtag aattgtctac tatcctagct ctattactat cccatcaagc
    21961 ataaaaaaaa tacaaaaaaa aggcttccat ggaagtaaag ctaaaactat tatttttgac
    22021 aaaggcagtc agctggagaa aattgaagat agagcttttg atttttctga attagaagag
    22081 attgaattgc ctgcatctct agaatatatt ggaacaagtg cattttcttt tagtcaaaaa
    22141 ttgaaaaagc taaccttttc ctcaagttca aaattagaat taatatcaca tgaggctttt
    22201 gctaatttat caaatttaga gaaactaaca ttaccaaaat cggttaaaac attaggaagt
    22261 aatctattta gactcactac tagcttaaaa catgttgatg ttgaagaagg aaatgaatcg
    22321 tttgcctcag ttgatggtgt tttgttttca aaagataaaa ctcaattaat ttattatcca
    22381 agtcaaaaaa atgacgaaag ttataaaacg cctaaggaga caaaagaact tgcatcatat
    22441 tcgtttaata aaaattctta cttgaaaaaa ctcgaattga atgaaggttt agaaaaaatc
    22501 ggtacttttg catttgcgga tgcgattaaa cttgaagaaa ttagcttacc aaatagttta
    22561 gaaactattg aacgtttagc cttttacggt aatttagaat taaaagaact tatattacca
    22621 gataatgtta aaaattttgg taaacacgtt atgaacggtt taccaaaatt aaaaagttta
    22681 acaattggta ataatatcaa ctcattgccg tccttcttcc taagtggcgt cttagattca
    22741 ttaaaggaaa ttcatattaa gaataaaagt acagagtttt ctgtgaaaaa agatacattt
    22801 gcaattcctg aaactgttaa gttctatgta acatcagaac atataaaaga tgttcttaaa
    22861 tcaaatttat ctactagtaa tgatatcatt gttgaaaaag tagataatat aaaacaagaa
    22921 actgatgtag ctaaacctaa aaagaattct aatcagggag tag
//
LOCUS       DBEJKC010000030        22355 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.030, whole genome shotgun sequence.
ACCESSION   DBEJKC010000030 DBEJKC010000000
VERSION     DBEJKC010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22355
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.030"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            179..1660
                     /gene="mgaSpn"
                     /locus_tag="ACL3G6_001240"
                     /gene_synonym="mgrA"
     CDS             179..1660
                     /gene="mgaSpn"
                     /locus_tag="ACL3G6_001240"
                     /gene_synonym="mgrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor transcriptional regulator
                     MgaSpn"
                     /protein_id="HGR0545772.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2022..3023
                     /locus_tag="ACL3G6_001241"
     CDS             2022..3023
                     /locus_tag="ACL3G6_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0545773.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3174..4091
                     /locus_tag="ACL3G6_001242"
     CDS             3174..4091
                     /locus_tag="ACL3G6_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0545774.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4102..4992
                     /locus_tag="ACL3G6_001243"
     CDS             4102..4992
                     /locus_tag="ACL3G6_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0545775.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            5021..6637
                     /locus_tag="ACL3G6_001244"
     CDS             5021..6637
                     /locus_tag="ACL3G6_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0545776.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVENLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6647..7966
                     /locus_tag="ACL3G6_001245"
     CDS             6647..7966
                     /locus_tag="ACL3G6_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGR0545777.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKIEQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(8176..8248)
                     /locus_tag="ACL3G6_001246"
     tRNA            complement(8176..8248)
                     /locus_tag="ACL3G6_001246"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8213..8215),aa:Lys,seq:ctt)
     gene            complement(8513..9784)
                     /locus_tag="ACL3G6_001247"
     CDS             complement(8513..9784)
                     /locus_tag="ACL3G6_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HGR0545778.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            10054..10254
                     /locus_tag="ACL3G6_001248"
     CDS             10054..10254
                     /locus_tag="ACL3G6_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545779.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQ"
     gene            10458..10637
                     /locus_tag="ACL3G6_001249"
     CDS             10458..10637
                     /locus_tag="ACL3G6_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545780.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10774..10953
                     /locus_tag="ACL3G6_001250"
     CDS             10774..10953
                     /locus_tag="ACL3G6_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HGR0545781.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            10990..11442
                     /locus_tag="ACL3G6_001251"
     CDS             10990..11442
                     /locus_tag="ACL3G6_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HGR0545782.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11733..12203
                     /locus_tag="ACL3G6_001252"
     CDS             11733..12203
                     /locus_tag="ACL3G6_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HGR0545783.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFIMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            12259..12801
                     /locus_tag="ACL3G6_001253"
     CDS             12259..12801
                     /locus_tag="ACL3G6_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545784.1"
                     /translation="MLEKVKQFFRSRSAKTEPSVDILPRNRFEDLDFERVLKSGARRL
                     VNEEGRYAEDGKITELEFPEDFAEFEFLVGFKTEEEEQFQQLLARLNSIDNAIQSYLE
                     SEMQQPIPQYAKDLGYTQKRWEKTFYFHPWILSGEENPPNLRYVADYVNDEFTVYFAK
                     KHGRWQAYWDAECQKVIEES"
     gene            12851..13015
                     /locus_tag="ACL3G6_001254"
     CDS             12851..13015
                     /locus_tag="ACL3G6_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7,8-dihydro-8-oxoguanine-triphosphatase"
                     /protein_id="HGR0545785.1"
                     /translation="MELLNSRMDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPG
                     GGKSVRENLI"
     gene            13125..14159
                     /locus_tag="ACL3G6_001255"
     CDS             13125..14159
                     /locus_tag="ACL3G6_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGR0545786.1"
                     /translation="MKKSDVLDLIKYHYEGRETEFRNQSIAIARNFNKHGDTQIAQYI
                     MGLMSQSDRFMPQIENPSEYLTPAKLDIGPLPLPLSIMNDLKGIINAVNHHIGINKFL
                     FVGSPGTGKTESVKQVARLIGKELLVVDFSHLVDSKLGQTVKNLATLFNEINNLPFKQ
                     NYIILFDEIDSIVLDRVNQNDLREMGRVTSAFLKELDRLSPEIVLIATTNLFENLDKA
                     VTRRFDAIIDFDRYTDEDKVEVATIILNELLKQFKNVARDLKLFKKIINSANVIPNPG
                     DLRNSIRTSLAFSDPSDPHDYQKRLLRSLHNGRNLSISKLSKLGFTVREIEILTGISK
                     SSVSRELSED"
     gene            14161..16404
                     /locus_tag="ACL3G6_001256"
     CDS             14161..16404
                     /locus_tag="ACL3G6_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008288790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGR0545787.1"
                     /translation="MNTLLTLRGKSFTPKSAKGRGPITIPADSIVTLNHLNELYTSLE
                     RVKEYWSNNTIIDGVLISVYYNRVLAKSNRIDGFFNVGGGNAIPNETIVGAKFSNDKS
                     RHIITHYISKEVLDKTIEHTKKVITIFKDYFASAPMTSMVFSDSSKFNQIDYSKYGLS
                     KSKFKQYLRDACFVKGFGIEQADMSTIRNSIVTIYDVKTNLLTLLKQLDIDVSEANIM
                     DQTTVLLDEKNIELLLLKAPYLVSMIVEDFSSLSPENFYNDGNTFYNNLPFPTNEPII
                     GVIDTLFDDRVYFNEWVEYHDLISPDISKGSQDYKHGTAVSSVIVDGASLNPKLDDGC
                     GRFRVRHFGISLQSGFNSFTIIKQIREIVSQNPDIKVWNLSLGSNDEIRENFISVEGS
                     LLDEIQFDNDVIFIIAGTNGIAPDGQRKKIGAPADSLNSIIVNSVDFSNQVVSYSREG
                     VVLSFFIKPDVSYYGGGNGDFINVCEPLGLARVAGTSFAAPFIARKMAYLIHIMGLSR
                     EEAKALLIDSAIPWNDKKTFADISLLGYGVVPIKIEDILSTPDDEIKFIVSDVSRAYE
                     TYNYDFPVPISKEHYPYVAKATMCYFPKCSRNQGVDYTNTEMQLSLGVLDKKGIKTIN
                     NDNQYSENAPGYVREKSARNIFRKWDNVKHLGEKFSSRKKAKPILNPSNPQWGMSVKT
                     IERLRNDDGYGIRFGVVVTLKELNGVNRIEDFIQQAELRGWLVNRLQVEAQVDLFNSL
                     NEEIEFE"
     gene            16455..17474
                     /locus_tag="ACL3G6_001257"
     CDS             16455..17474
                     /locus_tag="ACL3G6_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbiH family protein"
                     /protein_id="HGR0545788.1"
                     /translation="MNITYIVGNGLDLQYGLKTRYKDFYEFQNRTYISRKENEEEYSN
                     LIYESLFSDTVNDYENWSDFELSIGKLTKDNDLISSSIEIKEKFIDDFSEIVDDLREY
                     LRIQQEKNLEKGNAIDFISTLDNMRTSLPVINQPAIDKKYNENLYQHDIVNILTLNYT
                     NVIDKLYNESAKSFSNQLRTNNYKFHIAPPIHAHGTVDICTVLGVSDETQISNSFDEE
                     QKESLIKNLVLKNYRENMDVKNSDIIKNSDIIILYGVSLGETDGYIWNQIAEQSIRSS
                     VPVIIYHYVPHFDAGNPTRVKRLYRNVEDKFIQNSGIDLELEKKLRDNLIVVIGKTIF
                     NLMER"
     gene            17487..18437
                     /gene="prmA"
                     /locus_tag="ACL3G6_001258"
     CDS             17487..18437
                     /gene="prmA"
                     /locus_tag="ACL3G6_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HGR0545789.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     IFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVVAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            18439..19182
                     /locus_tag="ACL3G6_001259"
     CDS             18439..19182
                     /locus_tag="ACL3G6_001259"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HGR0545790.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            19193..20989
                     /gene="pepF"
                     /locus_tag="ACL3G6_001260"
     CDS             19193..20989
                     /gene="pepF"
                     /locus_tag="ACL3G6_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGR0545791.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETA
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(21049..21321)
                     /locus_tag="ACL3G6_001261"
                     /pseudo
     CDS             complement(21049..21321)
                     /locus_tag="ACL3G6_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            21309..21491
                     /locus_tag="ACL3G6_001262"
                     /pseudo
     CDS             21309..21491
                     /locus_tag="ACL3G6_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
     gene            complement(21516..21689)
                     /locus_tag="ACL3G6_001263"
     CDS             complement(21516..21689)
                     /locus_tag="ACL3G6_001263"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545792.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVDRTDEVSNHTYGKVKLTWFEEI
                     FEEYHTKKPCSSR"
     gene            complement(21701..22234)
                     /gene="queF"
                     /locus_tag="ACL3G6_001264"
     CDS             complement(21701..22234)
                     /gene="queF"
                     /locus_tag="ACL3G6_001264"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033739 - preQ1 synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046857 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors, with NAD or NADP
                     as acceptor [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
                     /protein_id="HGR0545793.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQINREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISINPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
BASE COUNT         7152 a         3743 c         4715 g         6745 t
ORIGIN      
        1 ctgtattcac gccctcaata gacggtaaaa taagaaaatt gtttatatat tgtctccgta
       61 gtgttattat acgaaataaa agattttagg aaaagtcgtt atatcatgct atacctattc
      121 tttgtggtat aattgcaaga ggtttaatcc gataatttat aaagagagaa agatattcat
      181 gagagattta ttatctaaaa aaagtcatag gcaattagaa ttattagaat tattatttga
      241 acataaacgt tggtttcatc gttctgaact agcagagtta ttaaattgta cagaacgtgc
      301 agtcaaagat gatctatccc atgttaaatc tgcttttcct gacttgattt ttcattcttc
      361 tactaatggt atacgcatta ttaataccga tgatagtgat attgaaatgg tttaccatca
      421 tttctttaaa cattcaactc atttttcgat tttagaattc atcttcttta atgaaggttg
      481 tcaagctgag agtatttgta aagaatttta tatcagttca tcttcgctct atcgtattat
      541 tagccaaatc aataaagtga ttaaaaggca atttcaattt gaagtcagtc tgacccctgt
      601 tcaaatcatt ggaaatgaga gagacattcg ttactttttt gcacaatatt tttcagaaaa
      661 atattatttc ctagaatggc catttgaaaa tttttcatca gagccactat ctcaattgtt
      721 agaattggtt tataaggaaa caagctttcc aatgaatttg tcaacgcata gaatgctaaa
      781 gttgctccta gttacgaacc tatatagaat aaagtttggt cattttatgg aagtagataa
      841 agattctttt aacgaccaaa gtttggattt tttaatgcag gcagaaggaa tagaaggtgt
      901 tgctcagagt tttgaatcag aatacaatat ctctttagat gaagaagttg tttgccaatt
      961 atttgtgtct tactttcaaa aaatgttttt catagatgaa agtctcttta tgaaatgcgt
     1021 aaaaaaggat agttatgttg aaaaatctta ccatctattg agtgatttta ttgatcagat
     1081 ttcagtcaag tatcagattg aaatggagaa taaggataat ctgatttggc atctgcataa
     1141 taccgcacat ctgtatcgtc aagagttgtt tactgagttt attttatttg atcaaaaagg
     1201 gaatacaatc aggaactttc aaaatatttt tccaaaattt gtttcagata taaaaaaaga
     1261 gctttctcac tatttagaga ctcttgaggt ttgttctagt tcaatgatgg taaatcatct
     1321 atcttatacc ttcatcactc ataccaaaca tttggtgatt aatttgctac aaaatcagcc
     1381 taaactaaag gttttagtta tgagtaattt tgatcagtat catgcaaaat tcgttgcaga
     1441 gacactttct tattactgta gcaataattt tgaactggaa gtttggactg aattagaatt
     1501 atcaaaggaa tctttagaag attcacctta tgatatcatt atttctaatt ttattattcc
     1561 tcctattgaa aataagagac tcatctattc aaataatata aacacggtct cactcatata
     1621 cttgttaaat gccatgatgt ttattcgatt agatgagtaa ccaaaaataa caaaaaaacg
     1681 ctatttcgcg tttgaactgt acctcaaaag ttagacagaa aaaatctaat ttttggggtg
     1741 tttttgttaa gaaaagacct tcaatcattt aagcaaaatg tacatctaga tttatagccc
     1801 tctaaaactc ttgctttttt tgtagaagat acgaaaaaag ccataaaacc aaggcttttc
     1861 ctgttttatg tagatgttta cacatgaaaa ttgaagtatt ttcaaaagct aattggagtg
     1921 attttattca tgatgggata aatgatctgg ccaaaaatga ttgagaaata gttgcttaaa
     1981 aagcatttgc atgatactat atattgaaag gaggtgataa tatggtagaa caaagaaaat
     2041 caattaccat gaaagatgtt gctttagaag caggagttag tgttggaact gtttcacgtg
     2101 taattaataa agaaaaaggc attaaagaag taactttgaa aaaagtggaa caagcgatta
     2161 aaactttgaa ttacattcca gattactatg ctagaggaat gaaaaaaaat cgaacagaaa
     2221 cgattgcaat cattgtacca agtatctggc atcccttctt ttcagaattt gctatgcatg
     2281 tggaaaatga agtctataag agaaataaca aattactctt atgttctata aatggtacaa
     2341 atagagagca agactatctg gagatgttgc gtcataataa agttgatgga gtggttgcca
     2401 ttacctatag tccaattgaa cattacttga cgtcaggaat tccctttgtt agtattgacc
     2461 gcacatactc agatattgcc attccttgtg tttcatcaga taatgatgca ggtggaagag
     2521 aagcagctaa acaattaatt agtaaaggat gtcagcattt agcctttgtg ggcggacata
     2581 atacaaccat taatgaaacc aaacgtcgta gaatttcatt tgaaaagtat gtccaagagc
     2641 ataaaatacc tcttagtatt tttgatttgg atgagacagt tactgactat tatggaaagc
     2701 tagagagttt cttggaagaa aattcttcta tagatggaat ttttacaatc aacgatttta
     2761 cagctttgga tgtgattgaa atactagaaa aaaatggcaa acgtattcct catgatgtcc
     2821 aaattattgg atacgatgga attaaaatgg ctggagatag agattatcta ctttcaacta
     2881 ttgaacaacc attggaagaa atggcaaaag aagcggttcg tattttgttt gatataattg
     2941 atggaaagac tgttaatttg cagacaatcc taccagtaaa atttgttgaa ggaaaaacaa
     3001 caaaaaatga aaataagtct tgacagaaag cgctatcaat gatagaatga attcagataa
     3061 aaagatttat ttttaaaaca aaaatgaaac gtttcaaaaa aagaaataaa aagacagcgc
     3121 caagcgctat cttttataga aaaaatgaaa cgtttcaaaa aaaggaggtt gctatgaata
     3181 gcaaagcgaa gcaagtttct ctttgggaaa gaatcaagaa acaaaaactc ttgttattga
     3241 tgactgtccc cggtttagtt ttaaccttta tctttaaata catccctatg tatggggttt
     3301 taatcgcatt taaagattac aatcctttaa aaggaatttt agggagtgat tggattggtt
     3361 tttctgagtt tacaaaattc atatcctctc ccaactttgg tatcttgtta gccaacacat
     3421 taaaattaag tatctatggt ttattgcttg gctttttacc accaatcatt cttgcgatta
     3481 tgctcaatca actcttgagt gaaaaagtca aaaaacgaat tcagctcatt ttatacgcac
     3541 caaactttat ctcagtcgtt gttattgtcg gtatgatttt cctcttcttt tcagtgggag
     3601 gaccaatcaa caattttctt tctatgtttg gaatgaaggc tgacttcttg acaaatccag
     3661 acttctttag acccttatac atctttagtg gtatctggca aggaatgggc tgggcttcaa
     3721 cgctctacac ggcaacattg gtaaatgtag atccagcctt agtagaagca gctcgactgg
     3781 atggagccaa tatcttccaa cgaatctggc acattgatat tccagctctt aagcctatta
     3841 tggttatcca atttgtttta gctgcaggtg gaattatgaa tgtcggatat gaaaaagcat
     3901 tcttgatgca gacatcgtta aatttgccaa cttctgaaat tatctcgaca tatgtctata
     3961 aagttggtct tgtatcagga gactattctt actcaacagc ggttggtttg tttaatgcag
     4021 tgattaacgt agtattgctt gttgcagtta accaaatcgt taaacgcatg aataatggtg
     4081 aaggaattta aggaggaaag tatgaaaaat tcgattatgg atacaaaatt tgatagacgt
     4141 atcttactct taaataaaat cattattgtc tttatcgttt tgatgacttt gcttccttta
     4201 ctttatatcg tcgtagcatc ctttatggat cctaaggttc tggttagtag agggattagc
     4261 tttaatccag ccgattggac tgtagaaggt taccagcgtg tattcagtga ccaatctatt
     4321 ctaagaggtt ttatcaattc tctactatac tcttttggat ttgcagcttt aacagtattg
     4381 ctatctgtgt ttacagctta tcctctttct aagaaagact tggttggacg tcgttggatt
     4441 aactacttct tgattgtgac tatgttcttt ggtggtggtt tagtcccaac ttacttgctc
     4501 gtaaaagaat tgggaatgct caatactcca tgggctatca ttgttccagg tgctgtcaat
     4561 gtttggaata ttattcttgc tagggcctat ttccaaggat tgcctgaaga attagttgaa
     4621 gctgctgtca ttgatggagc gaatgacttg cagattttct ttaaaatcat gcttcctctt
     4681 gcaaaaccaa ttatgtttgt tctcttcctc tatgcttttg taggacagtg gaactcatac
     4741 tttgatgcaa tgatttatat caaggatcca aacttggaac cattgcaact tgtacttcgt
     4801 aaaattctca ttcagagcca accaggtcaa gacatgattg gagcacaagc ggctatgaat
     4861 gaaatgaaac gtttagctga attgattaaa tacgcaacta ttgtcatttc cagcttgcca
     4921 ttgattgtta tgtatccatt cttccaaaaa tactttgata aaggaattat ggctggttca
     4981 cttaaaggat aaaaaaagaa aaaataaaag gagttttctc atgaaattca aaacattctc
     5041 aaaatcagca gttttgttga cagctagttt agcagtactt gcagcctgtg gctcaaaaaa
     5101 tacagcttca agtccagatt ataagttgga aggtgtaaca ttcccgcttc aagaaaagaa
     5161 aacattgaag tttatgacag ccagttcacc gttatctcct aaagacccaa atgaaaagtt
     5221 aattttgcaa cgtttggaga aggaaactgg cgttcatatt gactggacca actaccaatc
     5281 cgactttgca gaaaaacgta acttggatat ttctagtggt gatttaccag atgctatcca
     5341 caacgacgga gcttcagatg tggacttgat gaactgggct aaaaaaggtg ttattattcc
     5401 agttgaaaat ttgattgata aatacatgcc aaatcttaag aaaattttgg atgagaaacc
     5461 agagtacaag gccttgatga cagcacctga tgggcacatt tactcattcc catggattga
     5521 agagcttgga gatggtaaag agtctattca cagcgtcaac gatatggctt ggattaacaa
     5581 agattggctt aagaaacttg gtcttgaaat gccaaaaact actgatgatt tgattaaagt
     5641 cctagaagct ttcaaaaacg gggatccaaa tggaaatgga gaggctgatg aaattccatt
     5701 ttcatttatt agtggtaacg gaaacgaaga ttttaaattc ctatttgctg catttggtat
     5761 aggggataac gatgatcatt tagtagtagg aaatgatggc aaagttgatt tcacagcaga
     5821 taacgataac tataaagaag gtgtcaaatt tatccgtcaa ttgcaagaaa aaggcttgat
     5881 tgataaagaa gctttcgaac atgattggaa tagttacatt gctaaaggtc atgatcagaa
     5941 atttggtgtt tactttacat gggataagaa taatgttact ggaagtaacg aaagttatga
     6001 tgttttacca gtacttgctg gaccaagtgg tcaaaaacac gtagctcgta caaacggtat
     6061 gggatttgca cgtgacaaga tggttattac cagtgtaaac aaaaacctag aattgacagc
     6121 taaatggatt gatgcacaat acgctccact ccaatctgtg caaaataact ggggaactta
     6181 cggagatgac aaacaacaaa acatttttga attggatcaa gcgtcaaata gtctaaaaca
     6241 cttaccacta aacggaactg caccagcaga acttcgtcaa aagactgaag taggaggacc
     6301 actagctatt ctagattcat actatggtaa agtaacaacc atgcctgatg atgccaaatg
     6361 gcgtttggat cttatcaaag aatattatgt tccttacatg agcaatgaca ataactatcc
     6421 aagagtcttt atgacacagg aagatttgga caagattgcc catatcgaag cagatatgaa
     6481 tgactatatc taccgtaaac gtgctgaatg gattgtaaat ggcaatattg atactgagtg
     6541 ggatgattac aagaaagaac ttgaaaaata cggactttct gattacctcg ctattaaaca
     6601 aaaatactac gatcaatacc aagcaaacaa aaactagagg ttgattatgg gagataagaa
     6661 atacacagta gaaaaagcca atcgttttat agcagaaaat aaacatctcg ttaatactca
     6721 atataagcct gaagaacatt tttcagctga gattggttgg atcaatgatc caaatggatt
     6781 tgtctatttt cgtggagaat accatctctt ttatcaattc tatccatatg atagtgtttg
     6841 ggggcctatg cactggggac atgctaaaag taaggacttg gtgacttggg agcacttgcc
     6901 agtggcactt gctcctgacc aagattatga ccgaaatggt tgtttctcag gctctgccat
     6961 tgtcaaggat gatcgcctct ggctcatgta cactggacat atcgaagaag aaaccggtgt
     7021 ccgccaagtg caaaatatgg cattttcaga tgacgggatt cactttgaaa agattgaaca
     7081 aaatccagtt gcaactggat cagacttgcc agatgagttg attgctgctg attttcgtga
     7141 tccaaaactc tttgaaaaag atggacgcta ttactccgta gtagctgcca aacacaagaa
     7201 taatgtgggc tgtatcgttc tactagggtc cgataaccta gtagaatggc agttcgaatc
     7261 catcttttta aaaggggtag aacaccaagg ctttatgtgg gaatgcccag attacttcga
     7321 gttagatggg aaagattgcc ttattatgtc acccatgcgt tatcagcgtg agggagactc
     7381 atatcataac atcaactcat cgcttttgtt cacgggtaag gtagattggg gagaaaaatg
     7441 ttttatccca gaatcagttc aagaaattga tcatggccaa gacttctatg cgcctcaaac
     7501 attgttggac gatcaaaatc gtcgtatcct gattgcttgg atgcagacat gggggcgtac
     7561 ccttccaacc catgaccaag aacacaaatg ggcatgtgcc atgactttac ctagaatttt
     7621 aagattggaa gatggcaaac taagacaatt ccctgttaaa aaaggccaat atcaaatcca
     7681 aatagataaa gattgtcatt accacttagg aaatgatata gattatcttg aatttggtta
     7741 tgatagtaat gcgcagcaag tttacattga tcgtagccat cttattcaaa aaattctagg
     7801 tgaagaagaa caggacacta gtcgacggta tgtagatatt gaagctaaag aattggaagt
     7861 tgttctagat aaaaattcca tcgagatttt tgtcaatcaa ggtgaagcaa gcttgactgc
     7921 aacttattac ttaacggtgc cagctgagct atcacgaatt gattaaaaat taagttattt
     7981 ctcctaaaga aaaagttctc tttctaaaat agtggaaaga ggactttttg tgttttgggt
     8041 atataagctt agtttatggt atttgtaaaa ttggtgttgg attatgattt aagctagttt
     8101 tctaaagaat ttgaaaaaaa ttttatttaa gcaaaaaaaa cccttggttc caaggctttt
     8161 cctgttgtat ttatatgccc cctacaggga tcgaacctgt gacccacgga ttaagagtcc
     8221 gctgctctgc cagctgagct aaggaggcaa agaaaaaagc tgtattggtg ccgaaacttc
     8281 acggtttgta ttgaacccgc gcaattaagc aggtgggcaa ctcgctctaa ctgaagctgt
     8341 ttccgtgtga gacggcctac atgctgttag aagacttttg tttccctaat aatacaaaaa
     8401 atagtcggtc aacacttaag tgtgaagtcg tacaccacag cgtttctata cttatatgat
     8461 accacttttt caaaaaaaat caagaggaaa gtgcaatttt ttgaaaagga tttcagattt
     8521 ttcgcaaacg gtcgatagct tcctttcttt gagccaaagc ccgttcatat ttaccagtat
     8581 cttctgcttg gaaatagtga tgattacgaa ttttttctgg cagatagtct tgcttgaccc
     8641 aatttccagg atagttgtgt ggatagagat agtcttgggc attccccagt tccttgcttc
     8701 cactgtagtg cccatcacgt aggtgtcgcg gaataggcaa gtgccctgat gttttgaggt
     8761 cagcaagtgc cttatccata gctacatagg ctgagttgga ttttggagaa agggccaaat
     8821 caatcacgac attggcaatg agaatgcggg cttctgggaa cccaatcttc tgggcagcat
     8881 ccagagcagt cacggtatga atctgggcct caggattggc taagccgata tcttcatagg
     8941 cgataacagt caagcgacga gcgagactag gcagatcccc agcctcaatc aagcgggcag
     9001 tatagtggag actggcatcc acatctgagc cacgaataga cttttgcagg gcagatagaa
     9061 catcatagtg accgtctcca tccttgtcca tagtgatgta gcttctctga agactatttt
     9121 ccatgatgtc taaggtgatg tggcgaatgc cctcgtcatt ctcaggggta gagagaacag
     9181 ctaagtccag tgagttaaag gcagagcgaa ggtctccgtt tgtagaggtt gcgatgaaat
     9241 ccagcgcatc ctcatctagt tctattggaa aatcaaaacc acgttcaggg ttacttagag
     9301 ctatctgcag ggcctctttg acgtcttggt tagacagagg ttccaactcg aaaatttgaa
     9361 ctcggctacg aatggcagga gtgacagaga agaaaggatt ttcagtcgtt gctccaatca
     9421 tgatgaccag tccactttcc aagagaggca agaggaagtc ttgcttggtc ttatctagtc
     9481 gatgaatttc gtctagcaat aggacgagac caccagaaaa tttagcttct tccgagattt
     9541 cttgcagtcg ctttttacta tcaactgtcg cattgaaagt tcgaaaggca tacttggtcg
     9601 ttccagcgat ggcagaggca atactggttt tgccgattcc aggagggcca tatagaatca
     9661 tggaggacag gcggttggct tccaccatgc ggcggatgat ttttccaggt ccgaccagat
     9721 gctcctgacc gatgacctgg tcgatggttt tagggcgcat gcgaagcgcg agattgtctg
     9781 gcatagcagt cctttctagc gtggatttga gtagaatgac tcatctacta tatcttacta
     9841 tgtccattct agcctattag ttgtgatatt tcaatggttt tgtaataatc agggagtgag
     9901 atagaatctt ttttactatt taatttaatg aggagaggta tcagcatgag agatttgatt
     9961 ttccttaaag ctcaaaatag gatagttgag cctaaagaag tggaagtgct gacttgagaa
    10021 ataatattgc tgaatgtcat tgtatgaact ataatgaaaa gagaggtgat aagcaatgga
    10081 aatgatggac caagtcagga aattttgatt tttacaaaac aaattcgtca ttggattctt
    10141 agtgatcaag ttatttcagg gaaaagaaaa cttttcttcc gggaagatac tccaaaagag
    10201 attttagatt tgtacgaaaa cattaaatct aaacttgatt ttgcttacca ataagtttat
    10261 tctaataatg ggttgaaaaa atatgaaaaa tagaataatt gatgtttttg aagtagtaaa
    10321 tcgcatcctt gtaataactg ttgaaaatcc tgatttcgaa gacttgagag ttaatcatac
    10381 tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gctgtacttg agtacggtaa
    10441 ggcgacgttg acgtggtttg aatttgattt tcgaagagta tcagtttgta aaaattggag
    10501 ataaaaaata tagagtacgc agtgttccta tgattcattc aactccgcct caatctgtct
    10561 tagatcgaga tacttttaca attgactata cagatgatga attgctcgat aaagaagcag
    10621 tttttactac tcattagaaa aataggtctg aataaattgg cttcccttag aaccacatct
    10681 aggggctttt atgtataata gaataataag tatcactcct ttgcaatacg tgtaacacgt
    10741 gttataatgg tgttgtcagg aggtaaaagc gctatgccta tgacacaaaa agagatggtt
    10801 aaactcctta cggcccatgg ttggataaag actagaggcg gtaaaggctc ccatattaaa
    10861 atggagaagc aaggggaaag acttatcaca atccctcatg gtgagctgaa taagtacact
    10921 gaaagaggga taagaaagca agctgggttg taaaattcag cccctgtttt ttgatatgga
    10981 ggtagtgaaa tgttagttac gtatccagct ttattttatt atgacgacac agacggaaca
    11041 gaagcgactt attttgtcca tttcccagat tttgaatact cagctacaca aggagagggg
    11101 atttctgagg ctttggctat ggggtcggag tggctaggga taactgttgc agatttgata
    11161 gagagtgatg gagagttacc tcagccatca gatatcaata gcttgtcttt aattgataat
    11221 gatcctttta aagatgatga agatttcgtg tcaacctatg accttgataa atcttttatt
    11281 tctatggtat ctgttgatgt atcagaatac ctaggaagtc aggaacccat aaaaaagact
    11341 ttgaccatac caaaatgggc agataagttg ggacgagaaa tgggacttaa cttttctcag
    11401 actttgacag acgctattgc agataagaaa gttcaagcct aagattaagc gtggtatcgt
    11461 ggtaatagtc aataaaaaag cacgtccact tgtgctagtt actcgcctat tgattttata
    11521 gatttattag ccctttcgag ggctttttat attgattttt atgagaaatg aagaaatcag
    11581 acttttaaga aaatcactga taccaagggt ttaaatgagg taatatggta taattaggac
    11641 ataaaataat tttgtggtaa gatggtagta tctattttag catatttccg agcaatcggg
    11701 gcgattaaag agtcgcatag aaagaggaca aaatggcaac atacggattt ttagatgttt
    11761 tagaggaaga gttggacaag aactttccct ttgactttga gattagctgg gacaaacgca
    11821 accatgcggt agaagtgagt tttctattgg aagcgcaaaa tgctgcaggt gtggagatgg
    11881 tggatgaaga cggagaggtt tcatcagatg acattctttt tgaggaagcg gtccttttct
    11941 acaatcctgc caagtcaaca gtcaatgagg aagactattt gactgttatt ccttacctgc
    12001 ctaaaaaagg attttcccgt gaatttttag cttattttgc gcttttcctt aaagatactg
    12061 ctgaggttgg gctagatgtc ctcatggact ttttggaaga cccagaagca gaggaattta
    12121 tcatggaatg gaaccaagaa gtctttgaag aaggaaaagt tggcttggaa gagggagaat
    12181 tttatcctta tccaaggtat tagaaaagat tctaagtgga catttttaaa taatgaattc
    12241 aaggagaagg gggagattat gctagaaaaa gtcaaacagt ttttcaggag caggtcagct
    12301 aaaactgagc cgtcagttga tattcttccc cgcaatcgct ttgaggatct agatttcgag
    12361 agagtattga agtcaggagc tcgtcgcctt gttaatgagg aaggacgcta tgctgaggat
    12421 gggaaaatca cagaacttga atttcctgaa gattttgcgg aatttgaatt tctagttggt
    12481 tttaagacgg aggaagaaga gcagtttcag caactattag ctcgtttaaa tagtattgac
    12541 aatgctattc agtcctattt ggaaagtgag atgcaacaac ccatccctca gtatgccaag
    12601 gatctcggct atactcagaa gaggtgggag aaaacctttt acttccatcc ttggatatta
    12661 agtggtgagg aaaacccgcc taatcttcgc tatgttgcag attatgtaaa tgatgagttt
    12721 acggtttatt ttgctaaaaa acatggcaga tggcaagcat actgggatgc agagtgccaa
    12781 aaagtaatcg aagaaagcta gctcgtattt tcctagagag taattgttat catagaaaag
    12841 agtaaatatc atggaattat tgaatagcag aatggatttc caaggttgca agattgccct
    12901 cttttgtggg gataagctac tgacgatttt gcgtgatgac aaggacgata tcccttgtcc
    12961 caacatgtgg gagttgccag gtgggggaaa gagtgtcagg gaaaatctga tatagttttg
    13021 cattaaaaga atatcctttc aaggttattc ttttttaatt ttgtcccaaa ataattgact
    13081 ttgtcccaaa aatatagtat tatttgtata aggaggaatg aatcatgaaa aaatcagatg
    13141 ttcttgattt aataaagtat cattatgagg gcagagagac agaatttaga aatcaatcca
    13201 tagcaattgc tcggaacttc aataaacatg gtgatacaca aatagcacaa tatattatgg
    13261 ggttaatgtc tcaaagtgat agattcatgc cacaaataga aaatcctagt gagtatttga
    13321 ctcctgctaa actagatatt ggtcctctcc cattgcctct ttcaattatg aatgatttaa
    13381 aaggaataat aaacgctgtc aatcatcata ttggaataaa taaattttta tttgtgggat
    13441 ctccaggtac tggaaaaact gaaagtgtaa agcaggtggc tagacttatt ggcaaggaat
    13501 tacttgtagt agatttcagt cacttagtag atagtaagct agggcaaaca gtcaaaaact
    13561 tagcaactct ttttaatgaa atcaataatc ttcctttcaa gcaaaattat atcatcctat
    13621 ttgatgaaat tgattccata gtgttggata gggttaatca gaatgattta agagaaatgg
    13681 gacgagtgac ttctgccttt ttaaaggagt tggataggct gtcaccagaa attgtattaa
    13741 ttgcaacaac aaatcttttt gaaaatcttg ataaagcagt tacgagaaga ttcgatgcca
    13801 taattgactt tgaccgttat actgatgaag ataaagtaga agtagctact attattttaa
    13861 atgagttatt aaagcaattt aagaatgtag ctagagattt aaaattattt aaaaaaatta
    13921 tcaatagtgc caatgtaata ccgaatcctg gtgatttgag aaactcaata agaacgtcat
    13981 tggcatttag tgacccatca gatccgcatg attaccaaaa acgcctgcta agaagtttgc
    14041 ataatggtag aaatttatct atttctaaat tatcgaagct aggttttact gttagagaaa
    14101 ttgagatttt gacaggtatt tctaagagta gtgtatcacg agagttaagc gaggattaaa
    14161 atgaatacat tattgacatt acgaggtaaa agttttacac caaagtcagc aaaggggagg
    14221 ggaccgataa cgattcccgc agattctatt gttacgctaa accatttaaa tgaactttat
    14281 acatcccttg aacgagtaaa agaatattgg tctaataaca caatcattga tggagtactt
    14341 attagtgtgt attataatcg tgtcctagct aagagcaatc gtatcgatgg tttttttaat
    14401 gtgggtggcg gaaatgcaat tccaaatgaa acgattgtgg gtgcaaaatt tagtaatgat
    14461 aagagtaggc atattattac acactacatt tcaaaggaag tgttagataa gacaattgag
    14521 catactaaaa aagttataac aatattcaaa gattattttg ctagtgctcc catgacgagt
    14581 atggtgttct ccgactcttc aaaatttaat caaattgatt attctaagta tggtctgtcg
    14641 aaatcaaaat tcaaacaata cttaagagac gcttgctttg tcaaaggatt tggtattgaa
    14701 caggcagata tgtctactat acgtaattct attgtaacaa tctacgatgt aaaaactaat
    14761 ctcttaacat tacttaaaca acttgatatt gatgtttcag aagctaacat catggaccag
    14821 acaactgttt tacttgacga aaaaaatatt gagttactac tgctaaaagc accttatcta
    14881 gtatcaatga tagtagaaga tttttctagc ctgtcaccag agaattttta taatgatggg
    14941 aacacttttt ataataatct cccttttcca actaatgaac ctattattgg tgtcatcgat
    15001 acgttgtttg atgatagagt ttatttcaat gagtgggtag agtatcatga tttaatttca
    15061 ccagatatta gcaaaggaag tcaagactat aagcacggta cagcagtttc ctcggtaata
    15121 gtagatggag ctagtttgaa tccaaaacta gatgacggat gtggaagatt tagagtcaga
    15181 cattttggga tatctttaca gagtggtttc aattccttca caattatcaa acagattaga
    15241 gaaattgtgt ctcaaaatcc tgatattaag gtttggaacc tttcgcttgg atcaaatgat
    15301 gaaattaggg aaaactttat ttctgtcgag ggttcgttgt tagacgagat tcaatttgat
    15361 aacgatgtaa tttttattat tgcaggcact aatgggattg cccctgatgg acaacgaaaa
    15421 aagattggag caccagcaga ttcactcaat tcaattattg taaattctgt tgattttagc
    15481 aatcaagtcg tttcttattc acgcgaagga gttgtcctgt ctttctttat caaacctgat
    15541 gtttcatact atggcggggg gaacggagac ttcataaatg tttgtgaacc actagggctg
    15601 gctcgagtag ctgggaccag ttttgcggct ccatttattg ctagaaaaat ggcttacctc
    15661 attcatatta tgggattaag tcgtgaagaa gcaaaggctt tattaattga ttcagcgata
    15721 ccatggaatg ataaaaaaac attcgcagac atttctttac ttggatatgg ggttgtgcca
    15781 atcaaaatag aagatatttt gtctacacct gatgatgaaa ttaaatttat agtctcagat
    15841 gtttctagag catatgaaac ttataattat gatttcccag ttccaatttc taaagaacac
    15901 tatccatatg tagcaaaggc cactatgtgc tattttccaa agtgttctag aaatcaagga
    15961 gttgactata ctaatacgga aatgcaactt agtttgggag ttttagataa gaaaggcatt
    16021 aaaacaatta ataacgacaa tcaatattct gaaaatgcac caggatatgt gagagaaaag
    16081 tcggcacgaa atatttttag gaaatgggat aatgtcaaac atttaggaga aaaattttct
    16141 tctcgtaaaa aagctaagcc gattctgaat ccttctaatc ctcaatgggg aatgagtgta
    16201 aaaacaattg aacggttaag aaatgatgat ggttatggta tccgttttgg agtagttgtt
    16261 actctaaagg agttgaatgg tgtcaataga atcgaagatt ttattcaaca agccgaatta
    16321 cgcggttggc tagttaatag attgcaagta gaagctcaag tagacctctt taatagttta
    16381 aatgaagaaa ttgaatttga atagtggata ttttatcctt attctagatc ttaggaacac
    16441 aagagggcaa agatatgaat attacttata tagttggaaa tggtttggat ttgcaatatg
    16501 gtttgaaaac aagatataaa gatttctatg aatttcaaaa taggacttac ataagtagga
    16561 aagagaacga ggaagaatat tcaaatctca tttatgagtc tctattttct gatacagtaa
    16621 atgattatga aaattggtca gattttgaat tgtcaattgg taaattaaca aaagataacg
    16681 acctcatctc ctcaagtata gaaataaagg agaaatttat agatgatttt agtgaaatag
    16741 ttgatgattt aagagaatat ctacgcatac aacaagaaaa aaatcttgag aaaggtaatg
    16801 caattgactt tataagcact ctagataata tgaggacctc tctccctgta attaatcaac
    16861 ctgctatcga taaaaaatat aatgaaaatc tatatcaaca cgatatcgtg aatatattaa
    16921 ctcttaatta cacaaatgta atcgataaat tatataatga gtcagcaaaa tcatttagca
    16981 atcaattacg aactaataat tataaatttc acattgcgcc tccaattcat gcacatggaa
    17041 cggtagatat ttgcacagtt ttaggagtta gtgacgagac acagatttca aatagttttg
    17101 atgaagaaca aaaagaatcc ttaataaaaa atttagtttt gaagaactat agagaaaata
    17161 tggatgttaa aaatagcgat attataaaaa attctgacat cataattctt tatggggttt
    17221 ctttgggaga gactgatggg tatatctgga atcagattgc tgaacaatca atcagaagtt
    17281 ctgttcctgt cataatttac cattatgtac ctcattttga tgcaggaaac cccactagag
    17341 taaaacgctt atatagaaat gtagaagaca aattcataca aaatagtgga attgatttag
    17401 agttagagaa gaaattaaga gataacctta ttgttgttat tggaaagact atttttaatc
    17461 tgatggaaag gtaagcaaaa tacataatgg aaacatggca agagttaaaa gttacagtga
    17521 agcgtgaggg agaggagttg gtttccaatc tcttgattga gctgggagcg caaggagtcg
    17581 caatcgaaga cagtatggac tatgtgggaa atgttgaccg ctttggcgag attttcccag
    17641 aggtggagca gcaagaagaa atcgtagtga cagcctacta ccctgacacg gtggatgtga
    17701 cagtggttga ggcggatttg caggctcgtc tagcagaatt gacagatttt atggatttgg
    17761 gagagttaaa aataggtacg actgccttgg ctgaggaaga ctgggcagac aactggaaga
    17821 aatactatga acctgctcgc atcactcatg atttgaccat cgttccctct tggacagact
    17881 atgaggcgac tgcgggagaa aaaattatca agctggatcc tggcatggct tttggtacgg
    17941 gaacccaccc aactaccaag atgagcattt ttgccttgga acaggttctt cgtggtggcg
    18001 aaacggtgct agatgtggga actggttcag gggttctctc tattgccagc tcgcttctgg
    18061 gggctaaaga aattttcgcc tatgacctgg atgatgtggc agttcgtgtg gctcaggaaa
    18121 atattgagct caaccctgga atggaaaata tccatgtagt ggcaggcgat ttgcttaaag
    18181 gcgtggagat tgaagcagat gtcatcgtgg caaacatctt ggcggatatc ctcattcatc
    18241 tgacagagga tgcttatcgc ttggttaagg atgaaggtta cctgatcatg agtggcatta
    18301 tcaaggataa gtgggacatg gtgcgcgagt tggctgaatc agctggattt ttcctcgaaa
    18361 ctcacatggt tcaaggggaa tggaatgcct gtgtctttaa gaaaaccaag gatatctctg
    18421 gtgtgattgg aggctagcat gcagcagtat tttgtaaaag gcagtgctat ctctcctgtc
    18481 actatcgaga acaaggaaac cagtaagcat atgtttcagg ttatgcgctt gaaagaagag
    18541 gatgaggtta ccttagtctt tgatgatggc atcaagcgct tggcgcgcgt gctggatatg
    18601 gaaaatcgtc agtttgagtt ggtccaagaa ttaaatgaca atgtggaact accagtccaa
    18661 gtgaccatcg catctggatt tcccaaggga gacaagctgg agttcatcgc tcaaaaagta
    18721 accgaactgg gtgctagcca aatctgggcc tttcctgcag actggtcagt tgccaagtgg
    18781 gatggcaaga aattgggtaa aaaagttgaa aaactagaaa aaattgccct tggagcagcc
    18841 gagcaaagca agcgtaatat tgtaccaagt attaaacttt tcgagaaaaa agcagatttt
    18901 ctagctcagc tggaccagtt tgactctatc atagtagcct atgaagaatc agctaaagaa
    18961 ggagaagccg ctgcgcttct gcaagcagtc actggtcttg aaacaggagc caaactgctc
    19021 tttatctttg gtccagaagg cggtctctca cctgcagaaa tcgaaagttt tgaagctaag
    19081 ggagccgttt tggcaggcct aggtcctcgt attttgcgag cagaaacagc accgctttac
    19141 gctttatcag cccttagtgt tttagtagaa ttagagaaat aagaggaaga aaatggaaca
    19201 aaaacaccgt tcagaatttc cagagaagga actctgggac ttaacagccc tataccaaga
    19261 ccgtgaggat ttcttgcgtg caatcgagaa agctcgcgaa gacatcaacc agtttagccg
    19321 tgattacaag ggcaatcttc acacttttga ggatttcgag aaggcctttg cggaattgga
    19381 acagatctac attcagatga gccatattgg caactatgct tttatgcctc agacgacgga
    19441 ctatagcaat gacgaatttg ccaatattgc ccaagctggg atggaatttg aaacagctgc
    19501 cagcgtagcc ttgaccttct ttgacgatgc cttggtggca gcagacgagg aagtcttgga
    19561 ccgtttgggt aaattgccac atttaacagc tgccattcgt caggctaaaa tcaaaaaagc
    19621 ccactactta ggggcagatg tggagaaggc cttgacaaat ctcggtgaag ttttctatag
    19681 tccgcaggac atttatacta agatgcgagc tggggatttt gaaatggctg actttgaagc
    19741 ccatggcaag acctataaaa acagctttgt cacctatgag aatttctacc aaaatcacga
    19801 ggatgctgag gttcgtgaga aatccttccg ttccttctca gagggacttc gtaagcacca
    19861 aaatacggct gcagcagcct atctggctca ggtcaagtct gaaaaactct tggctgatat
    19921 gaagggatac gactctgtct ttgactatct tctagctgaa caagaagtgg accgtgtcat
    19981 gtttgaccgc cagattgacc tcatcatgaa ggactttgca ccagtcgctc agagatacct
    20041 caagcatgtt gccaaggtaa atggtcttga aaagatgacc tttgcagact ggaaattgga
    20101 cttggacagc gccctgaatc ctgaagtgac tattgacgat gcctatgatt tggtcatgaa
    20161 gtcggtagaa cctttggggc aagaatattg tcaggaagtt gctcgttacc aagaagagcg
    20221 ctgggtggat tttgctgcta acagtggcaa ggattccggt ggttatgcgg cggacccata
    20281 tcgcgtacac ccttatgtac tcatgagctg gacaggccgt ttgagcgatg tctatacctt
    20341 gattcatgaa atcgggcatt ctggtcaatt catcttttca gacaatcacc aaagctattt
    20401 caacgcccac atgtcgacct attatgttga agcaccgtca accttcaatg aattgctact
    20461 cagtgattac ttagagaacc agtctaatga cccacgtcaa aaacgcttcg ctctggctca
    20521 tcgcttgaca gacacctact tccataattt catcacccac ctcttggaag ccgccttcca
    20581 gcgtaaggtg tatacattga ttgaagaagg ggagaccttt ggagcaagca agctcaacag
    20641 cattatgaag gaagttttga cagatttttg gggcgatgcc attgaaatcg acgacgatgc
    20701 agctttgact tggatgcgcc aagctcacta ctatatgggc ttgtatagtt acacttactc
    20761 tgctggtctt gtcatctcga cagctggtta ccttcatctt aaaaactcag aaactggagc
    20821 tgaagactgg ctcaatctcc tcaaatcagg tggtagcaag acaccacttg agtcagccat
    20881 gattatcggt gctgatattt caacagacaa accactccgt gataccatcc aattcttgtc
    20941 tgacacagtt gaccagatta tcgcctacag tgctgagttg ggggagtaag gggatagaga
    21001 ggttgttata gaatgggtat ggacagttat ttgcttaaaa gtccatgttt aaatccccca
    21061 ttccttttcg aggaattctt tgcccttctc tgtaatggta agtgaacgtg gcgtttgtgc
    21121 agggatgacc aattgttttt cactgaaaaa ttctaaaaga gcattgccga gagctccgcc
    21181 gacatgattt ttacgttcgc tccaatccaa acatttaggg caaaatttcc gttttttctt
    21241 tttcaattca tccgtatcaa tgtgtaattt tctttggaaa taagacttcc cagcttcagt
    21301 gagttggaag tctttttctg atcggattga agattactgg actttcagta aacccagctc
    21361 gtagcttggc accagctgtc ttggtgggcg gcgcagccct tcaacaagtt tggattttca
    21421 tccttgcacc aatcgctggt ggagttcttg cagcccttgt tgcaaaaaat ttccttggaa
    21481 cagaagaata attgaaactc aaaaagcctt gctcctcatc ttgaggaaca gggctttttc
    21541 gtatgatact cttcgaaaat ctcttcaaac cacgtcagct tcaccttgcc gtaggtatgg
    21601 ttactgactt cgtcagttct atccacaacc tcaaaacagt gttttgagta acctgcggct
    21661 aacttcctag tttgctcttt gattttcatt gagtatgact ttagcggttg tcaattttct
    21721 ctggataaag gtcgtgttgg aagaggcgtt gttctgccaa gccctcatac ttagttcctt
    21781 gcttaccgta gttgtagtag gggttgattg aaatgccacc gcgcggagtg aatttccccc
    21841 agacttctaa atagcgaggg tctagcaagt tgaccaagtc tttcccgatg gtgttgatac
    21901 agttttcgtg gaaatctccg tggtttcggt agctaaatag atatagtttg agggattttg
    21961 actcgacaca gagtttgtca ggaatgtagg aaatatgaat cgtcgcaaag tctggctgag
    22021 cagtgatttg tcccagcaga gacatatcga ggatatggtg acgaatgccc tgttccttag
    22081 cgatttctct attaatttga atttcgaggt gatgacgttg gccgtaggca aaggtgacag
    22141 cttcgactgt ttcatagtgt tgcatggccc agaaaaggca ggttgttgaa tcttgaccac
    22201 cactaaagac gaccaaggct gattgacgtt tcatagtact ccttccaaaa tgggaaatgt
    22261 tcagagcatg caaaaagctc ccattaggga gctaaaaaat accaaatcga gtttttttag
    22321 cgatggcata tcccaaacat cgtaatattc tactt
//
LOCUS       DBEJKC010000031        21767 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.031, whole genome shotgun sequence.
ACCESSION   DBEJKC010000031 DBEJKC010000000
VERSION     DBEJKC010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21767
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.031"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..1952)
                     /locus_tag="ACL3G6_001265"
     CDS             complement(<1..1952)
                     /locus_tag="ACL3G6_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HGR0545794.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSKN
                     NLTVTSSGQDISKKYADEVESHLQSILKDVNKNLKKVQHTQNVDFNKKLSRIKTKYLY
                     GLKEKSEAELTLKTKETKEELTAAFEQFKKDTLKSGKKVAEAEKKAKAQKEEDRRNYP
                     TNTYKTIELEIAEAEVGVAKAELELEFAQAQVQIPQDTEKINAAKSKVEAAKSNVKKL
                     EKIKSDIEKTYLYKLDNSTKETPKPRVRRNSPEIKAKGRVKNYEEANIELSKYMTDLY
                     KLDNSTKETPKSRVRRNSPQVGDSRELKETIDKAKETLSTYMVTRLTKLDPSVFWFAD
                     LLMDAKKVVEEYKTKLEDASDKKSVEDLRKEAEGKIESLIVTHQNREKENQPAPQPGG
                     QAGGSMVVPPVTQTPPSTSQSPGQKATEAEKKKLQDLIRQFQEALNKLDDETKTVPDG
                     AKLTGEAGKAYNETRTYAKEVVDKSKKLLSQTAVTMDELAMQLTKLNDAMSKLKEAKA
                     KLVPEVKPQPENPEPKPQPEGEKPSVPDINQEKEKAKLAIATYMSKILDDIKKHHLKK
                     EKHHQIVALIKDLDKLKKQALSEIDNVNTKVEIENTVHKVFADMDTVVTKFQKGLIQN
                     TPQVPEAPKSPEVPKVSDTPKAPDTP"
     gene            complement(2031..2558)
                     /locus_tag="ACL3G6_001266"
     CDS             complement(2031..2558)
                     /locus_tag="ACL3G6_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HGR0545795.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            complement(2641..3972)
                     /gene="hk06"
                     /locus_tag="ACL3G6_001267"
     CDS             complement(2641..3972)
                     /gene="hk06"
                     /locus_tag="ACL3G6_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HGR0545796.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIYE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            complement(3969..4622)
                     /gene="rr06"
                     /locus_tag="ACL3G6_001268"
     CDS             complement(3969..4622)
                     /gene="rr06"
                     /locus_tag="ACL3G6_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HGR0545797.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDEITQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            complement(4943..7375)
                     /locus_tag="ACL3G6_001269"
     CDS             complement(4943..7375)
                     /locus_tag="ACL3G6_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGR0545798.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            complement(7377..7835)
                     /locus_tag="ACL3G6_001270"
     CDS             complement(7377..7835)
                     /locus_tag="ACL3G6_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HGR0545799.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRDLLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            complement(7958..8683)
                     /locus_tag="ACL3G6_001271"
     CDS             complement(7958..8683)
                     /locus_tag="ACL3G6_001271"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0545800.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLE"
     gene            complement(8683..9690)
                     /locus_tag="ACL3G6_001272"
     CDS             complement(8683..9690)
                     /locus_tag="ACL3G6_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0545801.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            complement(9729..10487)
                     /locus_tag="ACL3G6_001273"
     CDS             complement(9729..10487)
                     /locus_tag="ACL3G6_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0545802.1"
                     /translation="MRNLRSILRRHISLLGFLGVLLIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            complement(10450..10740)
                     /locus_tag="ACL3G6_001274"
     CDS             complement(10450..10740)
                     /locus_tag="ACL3G6_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HGR0545803.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     regulatory      complement(10811..10913)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(10996..12342)
                     /gene="cbpD"
                     /locus_tag="ACL3G6_001275"
     CDS             complement(10996..12342)
                     /gene="cbpD"
                     /locus_tag="ACL3G6_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HGR0545804.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSGG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSASTGGTHYFKTKSAIKTEPLASGTVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     gene            complement(12431..12697)
                     /locus_tag="ACL3G6_001276"
     CDS             complement(12431..12697)
                     /locus_tag="ACL3G6_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HGR0545805.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            complement(12699..14051)
                     /gene="dnaB"
                     /locus_tag="ACL3G6_001277"
     CDS             complement(12699..14051)
                     /gene="dnaB"
                     /locus_tag="ACL3G6_001277"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HGR0545806.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            complement(14094..14546)
                     /gene="rplI"
                     /locus_tag="ACL3G6_001278"
     CDS             complement(14094..14546)
                     /gene="rplI"
                     /locus_tag="ACL3G6_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HGR0545807.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            complement(14543..16516)
                     /locus_tag="ACL3G6_001279"
     CDS             complement(14543..16516)
                     /locus_tag="ACL3G6_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HGR0545808.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQIIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            complement(16652..17200)
                     /gene="raiA"
                     /locus_tag="ACL3G6_001280"
     CDS             complement(16652..17200)
                     /gene="raiA"
                     /locus_tag="ACL3G6_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HGR0545809.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            complement(17280..17942)
                     /locus_tag="ACL3G6_001281"
     CDS             complement(17280..17942)
                     /locus_tag="ACL3G6_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HGR0545810.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            complement(17939..19237)
                     /locus_tag="ACL3G6_001282"
     CDS             complement(17939..19237)
                     /locus_tag="ACL3G6_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0545811.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            19293..19928
                     /locus_tag="ACL3G6_001283"
     CDS             19293..19928
                     /locus_tag="ACL3G6_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HGR0545812.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            20213..21133
                     /gene="cysK"
                     /locus_tag="ACL3G6_001284"
     CDS             20213..21133
                     /gene="cysK"
                     /locus_tag="ACL3G6_001284"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HGR0545813.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLVLAPDNGERYLSTALYEL"
     gene            complement(21372..21737)
                     /locus_tag="ACL3G6_001285"
                     /pseudo
     CDS             complement(21372..21737)
                     /locus_tag="ACL3G6_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_068988785.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
BASE COUNT         6363 a         4913 c         3606 g         6885 t
ORIGIN      
        1 tgcggtgtgt ccggagcctt tggtgtatct gaaacctttg gtacctctgg gctctttggt
       61 gcttctggaa cctgcggtgt gttctgaatt aagccttttt ggaatttagt aacaaccgta
      121 tccatgtctg caaatacctt gtggactgta ttctcaattt ctactttggt atttacatta
      181 tcaatttcag aaagtgcttg ctttttaagt ttatcaaggt ccttaataag agcaacaatc
      241 tgatgatgtt tttctttctt cagatgatgt ttctttatat catctaaaat cttgctcatg
      301 tatgttgcta tagcaagttt agctttttct ttctcctgat taatatctgg tacgcttggt
      361 ttctcaccct ctggttgtgg ttttggctct gggttttccg gctgtggttt aacctctggt
      421 accaatttcg ctttagcttc tttcaattta gacatggcat cgttcaattt ggttaattgc
      481 attgccaatt catccattgt cactgctgtc tgtgatagaa gcttcttgct tttgtcaaca
      541 acttctttcg cataagttct agtctcatta taggcttttc cagcttctcc tgtgagttta
      601 gccccatctg gaacagtctt tgtttcatcg tctagtttgt tcaaggcttc ttggaattga
      661 cgaatcaagt cttgtaactt tttcttttca gcttcggtcg ccttttgtcc tggactttgg
      721 gaagttgatg gaggtgtttg cgtcaccggt ggtacaacca ttgaaccacc tgcttgtcct
      781 cctggttggg gtgctggttg gttttctttt tctctatttt ggtgagtcac gataagagac
      841 tctatttttc cttctgcttc ctttcgcaag tcttctaccg attttttatc tgaagcatcc
      901 tctaattttg tcttgtattc ttccacaacc ttcttagcat ccataagaag atctgcaaac
      961 caaaaaacag atggatccag cttcgttaaa cgagttacca tataggtaga cagagtttct
     1021 ttcgctttgt ctatcgtttc cttaagttct ctcgaatcgc ctacttgcgg agaatttctt
     1081 cgcactctag attttggcgt ttctttggtt gagttatcta atttatacaa atcagtcata
     1141 tatttagaaa gttcaatatt agcctcttca taatttttga ctctgccctt agcttttatt
     1201 tccggagaat ttcttcgcac tctaggtttt ggcgtttctt tggttgagtt atctaattta
     1261 tacaaatacg ttttttcaat atctgattta attttttcta gttttttaac attactttta
     1321 gcagcttcta ctttagattt agcagcatta attttctcag tatcttgagg tatttgaact
     1381 tgagcttgtg caaactcaag ctcaagctct gccttggcga cccctacttc tgcttccgca
     1441 atttccagtt cgattgtttt gtaagtattg gttgggtagt tacggcgatc ttcttctttt
     1501 tgagctttgg cttttttctc agcttctgct accttttttc ctgatttcaa tgtatctttt
     1561 ttaaactgct caaaagctgc ggttaactct tcttttgttt cttttgtttt taacgtcaac
     1621 tcagcttccg acttctcttt taatccatac aaatacttcg ttttaattct gctcaacttt
     1681 ttgttgaagt cgacattttg ggtatgttga acttttttca aatttttatt gacatccttc
     1741 aatatacttt gtagatgcga ctcgacttca tcagcatact tcttcgatat atcttgccca
     1801 ctagatgtaa ccgtgaggtt attcttactc ctaacccctt ctgcatggac tactcctcct
     1861 aagaacaagc tggcaactac tacactagct actccaatac taaatttacg aattgaataa
     1921 tgtacttttc tttcgctttt tgatgcaaac atgtttattt ccttctatat tttttcttta
     1981 accttactat atcacttcaa tatgaactgt atatgagtcg aattttgtat ttatctcttt
     2041 atgcttccat ttgggattat aacttcatgt aatagctttt cctcttcagc tattcgtcga
     2101 tacaaaataa ctgcataaac tggaaaaact aaaacaaaag tcatataggc atgactcaac
     2161 aaggtcaagc caatcaactc aggtaaaata tttaaaaagt aattagggtg ttttactgtc
     2221 ctaaacaaga tatgatctac atatttgtga ttattgacaa gcataagctt cactgtccaa
     2281 atatctccca acaagtgaat caccaacatc aacatcagca tagaaaaaat aagcaagact
     2341 aaaccaacca tgcccatgcc atcaaaaatt gtcttgtgca ccattgcctc aaccaagcaa
     2401 gagagataaa aaacaatatg agccatagtt aatcgttttg tattctcaac tccaaattct
     2461 ttcccgccat tgctaaggat tcgtttctca ttctctatcg aacgctttaa aaaaatcaat
     2521 cgaataaaga atgttactaa aataatcgct aataccatat tagtatcctt tcttttatct
     2581 acacaaagaa taacacactt atgttaaccc tatatgaact ttaataaaaa actaatctgt
     2641 ctacaagcta atcttaaatt ccataccgtg ttcataaggg agaaaactat aatccatttg
     2701 atagctttct aaaatattat tcacaatgta aagacccaaa ccggaacttt catccttatc
     2761 tgtcacgatt tgagaatgat aaaatatatc aaataaatgt tctagttctt ggtcacttag
     2821 aggcgcacat gtatttttga tagagagata gccatcttgc tcggatatga ttacgcgccc
     2881 atttttatct gaatatttaa ttgcattact aatcaggttt gtcaaaacct tatccaatgc
     2941 cctaagactc atgacgactc tggtagcatc tgtcaattga ttttcaattg taacacctat
     3001 tgaatgagct aattcttgat aacgtgataa aatatctact aaaactggct taacagtcaa
     3061 agtctcacga cactctgtcc actcttggaa tttagaagac tccagtactt cttccaataa
     3121 gtggctcatc tggtcaatct tatttatact ctttgcaata tattttggat gatctttgta
     3181 atctccaata ttatgctgca tattctctag gataattcta agactggcta aaggggtttt
     3241 caactcatgt gatgctccgc ggacaaagga aaccttttga ttttgcaatt ttacaatttg
     3301 ctcattacga ctttccaact cataaataac cttcaacaag tgctcataca taccattaat
     3361 ctgttttcca acttcaccaa cttcatcttt cctactttca tcaaaacgaa tattgtcatc
     3421 caaatcttgc attttactag tcacttctga aatgtaaaaa agaggattga gcaagcgttt
     3481 agtataaaaa taagaaaaaa caaaggaaaa agcaattgta accaaaaatg tatatgggag
     3541 atacaaaagc aaaatattct ttgcttcttt gtagacatcc accccgtgaa caaattgcac
     3601 tgttacctgt ttaccatctg ctgtactaac agacatatct aacatcacga tataatttga
     3661 tagctttcca tctttaatat ccaagtcatg cacaagaggg agccgcttat ctacaatatc
     3721 tcttttaagg tgagcagata tggtcaagga ctttgaataa gactggagta agcttggaat
     3781 ttcatcagat gtcttagtct ttaaatactc cgtaaacact cttgcgctct cattaaactt
     3841 ttccccctcc agttgaatat aataaaaagg aaaggtcaaa taaatagcta tatgaatgac
     3901 tagaccaaca ccacctagaa ttgcaaaact tcttaaaaag gacttggtta ataatttagg
     3961 attttttatc ataaactaat cttataccca acatttttca cagtcacgat acaatctaaa
     4021 gctaattttt tgcgaagagt acgaatatag acatcaacga ccctatcaca aggtaaatca
     4081 gctacatctt ttgaaatttc ttccaatatc tgctctctac ttaaaacttg atttttatgc
     4141 tgaatcaaac actttagtac cagtaattcc tttggtttga gatcaatttc ttcattttta
     4201 taatgtgctt tgtaagaggt aaaatccact gttacatcct gatatcgcca aatatcctct
     4261 atgacgtagt aacgtctgat aagcgcctta atacgcttga caagcagtac caaagaaaaa
     4321 ggttttgtca catgatcatc agcatagaga tcaaatacct gtgactgagt aatttcatct
     4381 cccagagcac tcaagacgat gacaggaata tcgtgctttt gattgatttc ttttaacact
     4441 tcaaaaccac tcttcctagg catcattaaa tccagtacca tgagatggat agggagatct
     4501 tgaaattttt ccaagacctc ttgtccatcc ttagccataa tgacatgata accctcttct
     4561 gtcagaaatg ctgcaattcc ttctctaatc atttcctcgt catctgcaac taaaatgttc
     4621 atctctctcc ctttctacta ccagaactcc atacatctat ttcctgtatg ctatttgaaa
     4681 atttcctacc agcctatcat ctatgataat agaatggatt tcatttatcc gctacttttt
     4741 gtcaacaaca acgtcaatac aagaaaatca ttcatcttgc agcttatact cttcgaaaat
     4801 ctcttcaaac cacgtcagct ctatctgcaa cctcaaaaca gtgttttgag caacctgcgg
     4861 ctagctgcct agtttgctct ttgattttca ttgagtttca ctccactgtg acttatggtc
     4921 agatgctggt acttttattc ttttatgcaa tatcaaattt taactggcct gctttgacac
     4981 caatcttaag tgtgctgcct gccactaaat ctcccttgag aagaagttct gccaacttgt
     5041 cctccacttc tgtttgcagg gttctgcgaa gtgggcgagc tcccatctct gggtcatatc
     5101 cttgatttgc taacaatttc agagctgaag cttgtaattt caagtcaatg cctttttcag
     5161 ccaaacttgc cactaaaggc ttgaccataa tcttcaccac ttcctgcata tgatcactag
     5221 ataggctatg gaagaccacc ttctcatcaa tacggttgat gaattccggt ctataagctt
     5281 ttttcagttc ttcaaacatg cgtttttcca tattttcctg gtcaaaacga atatccttag
     5341 ccccaaaacc aacagtctta tcatcacgaa gggcagtcgc acctaggttc gatgtcataa
     5401 tgataatggt atttgaaaaa tcgaccttgc gtcccttgct atctgtcaag acaccgtcat
     5461 ccagaacctg caagagaaca ttaaagatat ctgggtgagc cttctctacc tcatcaaaga
     5521 ggagaacgga atagggttta ttgcgaacct tctctgtcaa ctccccacct tcttcgtaac
     5581 ccacatagcc tggaggagct ccatttagac ggctggctgc gaatttctcc atatactcac
     5641 tcatatcaaa gcggataagg gctgattcgt catcaaagag aacttctgcc aaagccttgg
     5701 ccaactcggt cttaccgaca cctgtgggtc ctaggaacat aaaggaaccg atcggacgct
     5761 tgtgactgcg aattcctgac tgattacggc gaatcgcacg actaatactt gaaacagctt
     5821 gatcttgacc gataacccgt ttatggagtt ctgcttcaag atttagatat ttcttagcgt
     5881 cagtctgagt cagcttttga actgggattc ctgacaagcg actcaaggtg gtcaaaatat
     5941 cagactctgt caccaagtct ttgtagacag gtacttcctc ttcttttgcg attagctggg
     6001 ctgcctgttt ccacttgcca tccatcaggg ccttgtcagc tggactcaaa tctgaatcgt
     6061 ctgcttttac atgctttgcc ttattttgca ctgttgctgc tgcttcgtcc aagaggtcga
     6121 tagcagagtc tggcaagtga cgactggtta aataacgatg agccatctta accgctgttt
     6181 caaccgcttc atctgtgatt tgtacacggt gatgtttctc ataagtcgcc ttcaaacctt
     6241 gtaaaatagt catactatct gccacacttg gttcttcaat cgtcacttta gcgaaacgac
     6301 gagaaagtgc cgcatctttt tcgatatgtt tttgatattc ttcctgagta gtggcaccaa
     6361 ccgttctcaa agttccacgc gccaaggctg gtttcaagat attggccgca tccagagtcg
     6421 aatcaatccc gctaccagaa cccatgatgg tgtggagttc atcgataaag aggatgactt
     6481 ggccatcttc ttcaatatcc ttgatgatat tattcatgcg ttcttcaaag tcaccacgga
     6541 agcgtgtccc tgcaacgaca ttcatcaaat caagttctaa cacgcgcatc ttagccattt
     6601 ccgcaggcac gtcaccacta gcaatacgct gggcaagacc aagggccaga gctgttttcc
     6661 cgacaccagc atccccaacc aagacagggt tgttcttagt cttacggctc aagatttgaa
     6721 tcatacgtga gatttccttg tcccgaccga tgactggttc taacttgcca gaacgcgctt
     6781 gctctgtcaa atcatgcgta tagtcctcga gaccaccact aggagtctgc ggcatgccca
     6841 tcatattggc catagaattt tgcttgtcag ctactgtacg atggcgttgg cgtaaagcct
     6901 tgagatcttc acgagtccag cctgcacgtt cttctaaatt tcgacgaagg gcagcaatct
     6961 tgacctgatc tttcttgtct tcataagaaa aaccagccct ctccaagata cgagtcgcca
     7021 aggcattgcc atcatgcaaa atcgcataga ggacgtgctc tgtccctagt accttagcat
     7081 ggaccactga cgctacatac tctgcttcat caaaaagaac ctgcaaacga cgggagaacg
     7141 gcaattccgt aaaggtttca tcctggctat agtccgtttc agtcagttcc aaagccacct
     7201 cttctaaacg gtccatctca tacggataat catttaaagt tgcccctgct acactataac
     7261 tgtgattaga catggcaatc aacaagtgcc acgactctag ataacgagct ccaaaatgtc
     7321 cagcaaccat gtaggcactt tcgatacatt cattcaatgc ttttgaatag ttcatcttac
     7381 ttcccttttc tatctacctc ttgtatgacc tgacgtagca tgtttgctcg aacaactgga
     7441 gcttcttctc ctaaaacgcg atccaaagct actgattcta gcaaattcat ctcctgcttg
     7501 gtcatcaatt cctgctcaac caaaagctgg agaatatcct cataaatttc ttgactgact
     7561 cgctcaccaa tcgagtaaag cagatcccgg agcatttcat gatgactaga aaactcaatc
     7621 cgtcctatac gaatgtagcc tccgccacca cgcttacttt caaccaagta gcctctactt
     7681 tccgtaaagc gtgtcttgat cacgtagtta atctgactag gaacaacctg aaaggtatct
     7741 gccaactgac tccgttgcaa ctccacgata ccagattgat ctaaaatcgc cttgatgtag
     7801 gcctcaatat gatccgatgt atttttaaat ctcataacaa acccacctct ctctttaaac
     7861 cttgaccttg tttgactatt ataccgaaat tttctcattt ttaaaagaaa aagggcgctg
     7921 gtaaaggata atcttcacca actccctatt tttctactta ttctaagcct aattctgcca
     7981 agatttgacg tttgtaggca atcttttgga cttccttgtc ctcatcttca gaccaatcta
     8041 gtttaatttc tgaaacaatc tgcccagggc gatttttcaa gatatagatg cggtcgctga
     8101 gattgagggc ctcctcaata ctatgcgtga tgatcagagt tgttagctgc aactgtttgt
     8161 gaatctcaag ataccaagcg tggagttcca tctttgtcat ctcatccaag gcgctaaagg
     8221 cctcatctaa gagaaagagc ttgtgcccaa aaaggtaggt ccggagtaag gctacacgct
     8281 ggcgcatccc accgctaagt tcatgaggat acttgtctct tacagctgtc agctggaagg
     8341 tcgcaagaat tttatccgct cgggaaatag cttctgcctt atccaccttt tgaatcaaga
     8401 ggggcagaat gatatttcca agcaccgtct tgtgctccaa gagcagatcc ttttgcaaca
     8461 tataactcac gcgccccttg ggattttctt caccatcaag gacaattctc cctgactgaa
     8521 cttctaaaat cccagcgatt agattaaaga gggtggtctt tccaacacca cttgggccta
     8581 ggatggaaac cacttcgcct gaagtcacct gtagattgat atcctctaaa atcctctcct
     8641 gaccataggc ataactgacg tgctctagtc taatttctgt cattatttca caaattcgtt
     8701 ggtgaagcct ttgtctgtca agtcttcttt aaggatacca ttttctttat cccatttgta
     8761 gaaagcattc cagcgagctg cgtcaaattg accccatttt tccttgtcgc ttgcgtattc
     8821 ttttgacaag tatttttgag attcgatgac aaagtcacgt ttttccttga gttcaggtgc
     8881 attcttgatg agaatatctg cagcttcttc tggatgttcc atggcatatt ggtagccttt
     8941 tttgatggct tggatgactt tgcgagcttc ttctttgtta tctttcagat agtcgttgtt
     9001 tgcgatgata actggtgaat agtagtcaaa ctccttgaca tagtctttca agtacatgaa
     9061 gttagcatct acaccttgag atttagcaag gataccatcc caaccgtagt aaatccaagc
     9121 agtatcaaag acgccattgg caatcggtgt gattgagttt gagtcgttat ttggtacttt
     9181 ttcaaccttc tcaaagtctc caccttgaga ttctaccaag gttttcaaca tagcaagttc
     9241 agttgggtca ttccatgtcc catatttctt accaaccaag tcttttggac tgcttacatt
     9301 atcagattta cgagagatga ttcctgatgt attgtgttca acaatagctg caacggcagt
     9361 gattcctgct cctttttcca atttcttagc catgtagtct tggaaataca ctgcaaatgg
     9421 tgcctttccg ttgataacca agtcagaaga actttcttct ggtggcaatt tcaaatcaac
     9481 atccactcca gcttctttga aataaccttt ttccttggca acataaagcc ctgtgtggtt
     9541 ggtatttggt gtccagtcta ggataaagtc aaccttctta agttctgcct ctttgttgtc
     9601 tttagaagca gttccttgac cacaggccac aagcacaaca gctacaagag ctgttacaag
     9661 cgttaaaaac actttccatg ttttcttcat tttgatttcc tcttttcttt ttcagaaaca
     9721 ttctaattct acgaacgttt ccatttaatc acatattttt cactgatatc gaccagcttc
     9781 atacccaaaa gactgataat cgacaccaga ataataatgg caaacatggt atcatactga
     9841 aacaattttt tagactgaat catataaaca ccaagacctt caaaacctcc caaccactca
     9901 gataccacag ttgtgataaa ggcgtaggag acactgaccc tcagacctgc ataaaagtaa
     9961 ggcaggctaa ctgggatttt aaaatgccac aggatttgcc aaggcttggc ccgcatcaga
    10021 ctaaacaagg tcagcatatc cttgtcgcaa tgcctaaaac cgtccaaaat actaacgatg
    10081 atgggaaagg ttgtcgttaa gataatcaag acaatcttgg gcaaaatccc ataacctagc
    10141 cacaagacca ggataggagc tatggcaatg gtcggaatgg tctgaatgac caccatcata
    10201 gggtaaatca ggtcattgag ccaagtcaaa ctatccatga gcacagccat aagacaggca
    10261 atcaaaactc ccaaaatcag ccccagtaaa gccactctca aggtcgccca gctatggtgc
    10321 cagagaaatt ctctgtcacg aacaaagggc tggagaattt caagaggtgt cggcaggata
    10381 aacttgggga gaagtttaag aaaacctgct aactgccaga ttaacaagac tccgagaaag
    10441 cccaatagac taatgtgtcg tctcagtata cttctcaagt ttctcatcaa tacttaaaat
    10501 ctctcctaca tttattttga cattggcaaa gacattgtct gcctcctgcc ctgccacttc
    10561 cagcgcttct tttagaatgc gcataagctc atcaaactcc ccttccaaga ccgtttcaaa
    10621 tggtgtcact accatcgtca cttcttgagt ttgcagataa gcaatgacct gatcaataac
    10681 agctatccga tcaatcccct gtgctagggg taaaacttgc aaggcaatgc ttgctttcat
    10741 aagaacctcc tcttctcgtt ttccttttta aaaaaagaaa aacctttacc atacatggaa
    10801 aaggtgcaaa attagactaa gtatcgttcc ctccgctggc attacccaga tcaggtgcgg
    10861 tcgaagttta acacttcctc tcagactgta cacagactcc catatattat atgtatatat
    10921 gatagcgcaa aataagaaaa atgtcaagga aactgcttac agaaaagagc aggaaatttc
    10981 tcctactcca attttctata ctcgttctcc atcactgttt actctgtagc catccaccgt
    11041 cgtattaaca gctaaggcgc ctgaagagta agaataatac cacttaccag agacctggta
    11101 ccagcctgtt ttcattgccc ctgaactacc cagataatac cacgagccat tctcctttaa
    11161 ccatcctgtc tgcatttcac cagataattt caaataatac cagctagaac cgtctttcag
    11221 ccatcctgtt gatttagaac catttgattt gaaatgatac caactaccat ttattttctt
    11281 ccaaccgaca gttgaactat tattggatcc atagctagag atatttcctg attgattctg
    11341 ataattttgt gaagaagtca ctccctctag ctgtatatag cgacgacttc cattataggc
    11401 agtataactc aaccacttgt agccgtcttt ttcaagtatc tgatcataat gaaccttctc
    11461 tccaggataa tagtaatcaa tcacagttcc gctaactagg ggttcagttt tgatagcaga
    11521 cttggtctta aaataatgag ttccacctgt tgaagaaaga acagaattac ctagaggatt
    11581 tttattcaca gcctccaatt gaacataacg atagcttcca ttataggcag tataactcaa
    11641 ccacttatag ccgtcttttt caagtatctg atcataatga accttctccc caggataata
    11701 gtaatcaatc acagttccgc tagctagggg ttcagtttta atagcagact tggtcttaaa
    11761 ataatgagtt ccgcctgttg aagctgagga ttgactattc ccaacactgc cgccatccaa
    11821 atctttaaaa tgaataaatc ctgtcatcgt gtttgctttt ataactcgtt tattatagga
    11881 ttctgtataa ccatagttat attcctcaat ctcaatctga tctcccatta catttgacac
    11941 ccaggcaaca tgaccataag ttcctgcagt agaccaagta atggaaccaa tcgtcggtgt
    12001 attatctaca cgataacctt cccgacgagc acgatgtccc cattcattcg catttccata
    12061 agctgccgga atttcaaaac cattgacatt actcaaacga aaggctacaa aagaagtaca
    12121 ctgacgagaa tacatgcgcc actgatcaat ctcctggctc ccatttttat aataagcagg
    12181 ataatcatcc ccacgcgcaa tcgatccatt tcctccggaa taggcataga cactatcacc
    12241 agctgctagc atcaatccta ctactaaaaa aggaacaagc tttttaactg acatcttcaa
    12301 gtaataactt gtccctcttg ctataaacgg taaaattttc attcttcctc cttgaaaaat
    12361 aatataaagc gatgattgcc ttcacctaaa ttattcggag aaaaaagaaa aagtgagaaa
    12421 atttctcact ttagtcaaga taatgaatca aattcttttc tgtaagaata tctgagtaag
    12481 taaaggattc aacgtaaaca ttaacttgtt tatctccttc cacatcccca aactccacaa
    12541 taaatagaga tggataaact tcaattagct tacccaatct atttttttgg cgcttacgac
    12601 cattctccaa agtcatttct acgacttgtc cctcatgtgc cttgatttct tctttgattt
    12661 ttttcatctt ggctacatct gtaaatgcat ctgacatctt atgcctccct ctttgagata
    12721 cttgaaaatt tattgtattc tttttggaaa atcaattcca ctgttccacg agctccacta
    12781 cggtttttct cgataataac ttccacctta ttatttggga taccctcctc ttcttcacca
    12841 ccacgttcat agtagtcatc gcgatagaga aaagctacga tatcagcgtc ctgctcaata
    12901 gacccagatt cacgaatatc agacaagacc ggtctcttgt cctgacgttg ttctacacca
    12961 cgagaaagct gactcagagc gattactgga accttcaatt ccttggctag tattttcaac
    13021 tgacgagaaa tttcagaaac ttcttgttga cgattttctc gaccagttcc cgtgataagt
    13081 tgcaaatagt ctatcaaaat caaaccaaga tttccagttt cttgagccaa tttacgagaa
    13141 cgagaacgaa tctctgtaat ccgaatacct ggcgtatcat cgatatagat actggcgtta
    13201 gctagattac cctgagcaat agtatatttt tgccactcct catctgtcaa ttgccctgta
    13261 cggatagaat gtgactccac taagccttct gcagctaaca tacgatctac caagctttcc
    13321 gcacccattt cgagtgaaaa aatagcaacc gttttgtcca acttagtccc aatattctga
    13381 gcgatattca aggcaaatgc tgtcttacca actgctggac gagctgctaa gataatcaac
    13441 tcctcctcat gaagtcctgt tgtcatatga tccaaatcac gataacctgt cgcaatacct
    13501 gtaatatcgg tcgtttgttg cgagcgagct tccagatttc caaagttgag attcaacaca
    13561 tctcgaatgt tcttaaaccc gcttcgattt gcattttcac tgacatcaat caaccctttt
    13621 tctgcctgag caataatttc atcagctggt tgtgacgctt cgtaagcttg gttgacagac
    13681 tctgtcaact tggcaattaa acgacgtagc attgcttttt ctgcaacaat cttagcataa
    13741 tactccgcat tagcagaagt tggcacagaa ttaacaatct caaccaagta agacaagcca
    13801 ccaatattct gtaaatcacc ttgattatca aggatagtac gaaccgttgt tgcatctatg
    13861 gcatcaccac gatcggataa atcgaccatg gcttggaaaa tcaaacgatg ggcatactta
    13921 aaaaagtccc gagactcaat gtattctcgc acaaaaacaa gtttactctc atcaataaag
    13981 atagccccta aaacggattg ctcagctaag atatcttgag gttgtactcg taactcttct
    14041 acttctgcca tcagacttcc cttcttttac aatcttgtca agaaagtgta aacttatcct
    14101 tctttcacac gaagattgat tacacttgtg atatcttgat agattttcac tggcacatca
    14161 atcaaaccaa ccgctcgaat cggagcttgt acttgaatat gacgtttatc aatcttaatt
    14221 ccaaattgct tttgcaattc ttctgcaatc ttcttattgg taatagaacc aaaggtacga
    14281 ccatctggac caactttttc aacaaattct acaacagttt cttctgcttc aagttgtgct
    14341 ttaattgctt ttccttctgc aatcatctca gcgtgagctt tttcttccga tttttgttta
    14401 ccacgaagtt cacctacagc ttgagcagtc gcttctttgg ctagattctt tttgataaga
    14461 aagttttgcg cataccctgt tggtacttcc ttaatttcgc cttttttacc ttttccttta
    14521 acatctgcta aaaagattac tttcattctt ctttctcctt ttcctttatt tcatttaata
    14581 caatttctgt cagtttttca cctgcttctg acaaggttac atctttaatt tgagctgctg
    14641 ccaaattaaa gtggcctcca ccgcctaact cttccataat ccgttgtaca ttcagtttac
    14701 tacgacttcg agctgagata gagataaatc cttgtgtatt cttcgcaaga acaaaactcg
    14761 cttcaatacc tgacatggct aacatggcat ctgctgcctt actaataaca actgtatcat
    14821 agcatttcgt gtccttagcc tctgctatta gtacatctga acctaattta cacccctgta
    14881 aaataagttc attgacctca cgatattctt caaaatctgt cgcagcgatt tcctggatag
    14941 caatactatc acttccgcgc gttctgagat agctagcaac atcaaatgtc cgactagtta
    15001 ctcgcgaggt gaaattttta gtatccaaca tcataccagc catcaaaaca cttgcttgca
    15061 tacgactcaa acgatttttc ttagaattct ggaactgaat caattccgtt accaactcac
    15121 tggcactact tgcaccactt tcgatataag taataaccgc attatctgga aaatcctgat
    15181 cccttctatg gtggtcaata acaatgattt gggtaaataa atcataaaat tcttttgata
    15241 atgttaaggc tgtctttgaa tggtctacaa gaatcaacaa agaacgattg gtcaccatcc
    15301 ccattgcatc cttaacagac aacaacttcg taactccttc tttttctatg aatgaaacag
    15361 ctcgttcaat atctggagac atttgttctt catcataaag agcatagcta ttttcaatca
    15421 cattgctggc gaacaactgc atacctacag cagagcccaa agcatccatg tctaaatttt
    15481 tgtgaccgac tacaaaaacc tgatctacac tccgaatctt atctgaaata gctgtcatca
    15541 tagcgcgcgt acgagtccgt gtacgcttga ttgaagcagc agacccacca ccaaaataaa
    15601 ctggattttt cgtttcgtcg ttttccttaa caaccacctg gtcgccacca cgtacttcag
    15661 ccaagttcaa attgagcaaa gcaactttcc ctatctcatc atgatttcca tcgccataag
    15721 aaaatcccat acttaaggtc aagggcaact gtctctgttt cgactcttct ctgaaagcat
    15781 caataacaga aaatttatca ttcatcaagc cctcaagcac cgtgtagtca gtaaatagat
    15841 aaaatcgatc catacttacc cgacgagaaa acatcatgta tttttctgaa aactctgata
    15901 taaaattagc tacaaaacta ttgatttgac taatatctga ctcagaagtt gcatcctcca
    15961 aatcatcata attatccaca gagacaatcc caatcactgg tcgacttgtt accaattcat
    16021 ctgttatggc ttgttccctg gatacatcta caaaatacaa aacaccggaa gaagcatcca
    16081 tatgaacagc ataacgcttc tcaccaagct tggcataagt agacggattt cctactgaag
    16141 ccttgataat cgtttgaaca gcttctaaat caaaatcacc atcttccttg gtcaaaatca
    16201 attcagcata gggattaaac cactcaacct ctccagaaga taaattcaat ttcataacac
    16261 ctacaggcat ctgttccaat agagctgtca aactttcttc cgcttggtgg tttacatact
    16321 gtatctgttc tacatcactc cttgtataat gcactctcag tttcttaaat aaaaaaacat
    16381 agcctcctac aaaaagaaac aaaattaaaa ccgtcaacag attattatta acaaaaataa
    16441 tgaaagtgga taagactcca aacgcaatca atcctactag aataggaaaa attggactta
    16501 cataaaattt tttcattcaa aacctcttgg cacccattat accataatac ccctcaaaaa
    16561 gcgacttttt aaaagtgtaa tcagtaattc tatcaattat aagaaaaagg tagtttacaa
    16621 ttcagtaaac ctacctttac acatattgaa attaagattc tttaacctct aacaaaccaa
    16681 tttcgccatc ctcacgacga taaatcacat tggttgtctg atcttcaaca tccacataga
    16741 taaagaaatc atgccccaat aaatccattt gtagaattgc ttcttccaaa tccattggtt
    16801 ttaaatcaat ttgttttgaa cgaacaactt tagactggac aatatttgaa tcttccacca
    16861 aagcatctgt aaataattga ccagttgcta ccttattttt atttttacgc tcgatttttg
    16921 ttttattttt acgaatctga cgttcaattt tatcagttac aaggtcaatt gaaccataca
    16981 tatcttgaga tacatcttct gcgcggagag taatagatcc aagcggaatc gttacttcca
    17041 ctttagccgt tttttcacga taaactttta agttaattcg ggcatccaac tcttgttctg
    17101 gttggaagta cttttcgatc ttttcgagtt tagaaactac ataatcacga attgcttctg
    17161 ttacttctag gttttcacca cggatactat atttaatcat atgagtacct tctttctaaa
    17221 catttttgtt tttatgattt tattataacg ctttcattct atttttgcaa attttttcct
    17281 catcttacaa gggaaaatgt ttttacatcc ttagcaccag cttcttccaa cagtttctta
    17341 acacgattta tagttgctcc tgtagtatag atatcatcta taagtaggat ttttttagga
    17401 atagtgactc cacttttaat aaagaaagga agttctgtcc ccaagcgctc tgaacgattt
    17461 ttagaagaac tggctctctc ttctcttttc tctaataaat ccagatactc aaagcctgct
    17521 gcctctacca agccctcaac ctgattaaat cctctgttag catatctatc aggacttagg
    17581 ggaattacaa caaattgata ctctttgtac tttttcaact cctcacttaa aaatgaagcg
    17641 aaaacttttc ttaacaggaa gtctccatca aacttatacc gactgaaaaa atccttcata
    17701 gcttgattgt aagtaaaaat cgctctatga ctgacttcaa ctccttcttt acaccaaagt
    17761 tgacagtctt gacactttgt tgacaactct gttttcatac aatttggaca gttctcttcc
    17821 ccaattcttt caaaagtaga atcacagtct gaacaaagac aagagtcatc attcctcaga
    17881 agtaagagac tactaaaagt taaaacagtc ttcatagtct gcccacataa caagcacttc
    17941 atagaccagc ctccttattc atcatctgaa tttccttaat cgccttcttg attgaagcat
    18001 ttaacccatc atggaagaaa agcaaatctc ctgtcggtct atccatgctt cgtccaactc
    18061 gtccaccaat ctgaatcaaa ctagacttgg taaacaaacg atgattggcc tctactacga
    18121 aaacatccac acaagggaag gtaactccac gctccaagat tgtcgtactg ataagtattg
    18181 tcagttctcc atctcgaaaa gcttgtactt gctctaatcg atcctctgtt acagaagata
    18241 caaagccaat tttctcattt ggaaattgct cctgtaagat ttcttctaac tgctcccctt
    18301 tcttaatttc tgaagcaaaa atgagtaacg gataagctgt ctttctctgc ttctcaatat
    18361 aggactttaa ctttggtgac aaacgattct tgtctaagta gcgattaaaa tccgataacc
    18421 aaattggttt tggaataatc aacggatttc catgaaaccg tctcggtaaa ctcagtcttt
    18481 ttagttctcc taaacggacc tttttatcta actcattggt cgaagtcgct gttaaaaaga
    18541 ttctcaatcc attctccttt acactattct tgacagcgtg gtaaagcgtg ggattatcaa
    18601 cataaggaaa agcatctact tcatccacta tcagcaaatc aaaagcttga taaaacttca
    18661 ataactgatg ggttgttgca acaactagtg gtgttcgaaa ataaggttcc gattctccat
    18721 gtagcaaagc tatcccgcaa gaaaaatcct gttgcaggcg cttgtacagc tccaaacaaa
    18781 catctatgcg aggactagcc aaacacactg caccacccgc attgatcact ttagccacta
    18841 cttgataaat catttctgtc tttccagctc ctgttaccgc atgaactaag gttggctttt
    18901 gcttgtctac tgcttgaagc agtccctctg acaccttctc ttgaaaagga gttaattggc
    18961 cgcgccattt gagaacatct tgcttcggaa aatcctcctg cggaaaatag tataaagttt
    19021 gatcacttct gactcgcttc atcagcaagc actctcgaca atagtaagca ccgatgggca
    19081 aataccattc ttctagaata gtactattac aacgttgaca gaaaagtttc cccttctcct
    19141 ttctcattgc tggaagtttc tccgccaact gacgttcttc ttctgttaat tcattctcag
    19201 taaataaacg accgagataa tctaaattta ctttcatact tctttattcg taaaaactag
    19261 cactttagat tattttttag tacaattaaa tcatggaatt taggacaatt aaagaggacg
    19321 gccaagtcca agaagaaatc aaaaaatctc gctttatctg ccatgccaag cgtgtttata
    19381 gcgaagaaga ggctcgtgac ttcattactg ccatcaaaaa agaacactac aaagcgacac
    19441 ataactgctc tgcctttatt attggagaac gtagtgaaat taaacgtaca agtgatgatg
    19501 gtgagcctag tggtactgct ggtgttccca tgcttggggt actagaaaat cacaatctca
    19561 ccaatgtctg tgtggtcgtg acacgctact ttggtggtat taaactaggc gctggaggac
    19621 taattcgtgc ttacgccggc agtgtcgcct tagctgtcaa agaaattggt attattgaaa
    19681 taaaagaaca ggctggcatt gctattcaaa tgtcttatgc tcagtaccaa gagtacagta
    19741 acttccttaa agaacatgat ctcatggagc tggatacaaa ctttacagat caagtcgata
    19801 cgatgattta tgttgataaa gaagaaaaag aaactattaa agctgcactt gtggagtttt
    19861 ttaatggaaa agtcacttta actgaccaag gtttacgaga ggttgaagtt cctgtaaact
    19921 tagtgtaaac aatgaataat acagcgtttc gttgacattc tcacaactac tttagcgagc
    19981 aaaataaaaa gatgcgtacc aaaatatact agaaaatgaa gcaattcaaa cgaaacctga
    20041 tatcgttttc cttcacacct atttactaga attaactgaa cgcaatcact tgaaaattaa
    20101 tgactttgat ctatgatata tagaaatcct atcgcttcga taggatttct atattttaca
    20161 aatggtatgg atagcgttat actaaagata tcttatacaa agaggtattc atatgtctat
    20221 ttataacaac attactgaat taatcggtca aacaccgatt gttaaactta acaacatcgt
    20281 gccagaaggt gctgcagacg tctatataaa gcttgaagca tttaatcctg gttcatctgt
    20341 aaaagaccgt attgccctta gcatgattga aaaagctgaa caagatggta ttctgaaacc
    20401 tggttctact attgttgaag caacaagtgg aaacactggt attggacttt catgggtagg
    20461 tgctgctaaa gggtataaag tcgtcatcgt tatgcctgaa actatgagtg tagaacgacg
    20521 taaaattatc caagcttatg gtgctgaact cgtcctaact cctggtagcg agggaatgaa
    20581 aggtgctatt gctaaggctc aagaaatcgc tgctgaacgt gatggtttcc ttcctcttca
    20641 atttgacaat ccagctaatc cagaagtaca cgaaagaaca acaggagctg agatactagc
    20701 tgctttcggt aaagatggat tagatgcctt tgttgctgga gtaggtaccg gtggaacgat
    20761 ttctggtgtt tctcatgcac tcaaatcaga aaattctaac attcaagttt ttgcagtaga
    20821 agcagatgaa tctgctattc tatctggtga aaaacctggt cctcacaaaa ttcaaggtat
    20881 ctcagctgga tttattcctg atacacttga tactaaagcc tatgatggta tcgttcgtgt
    20941 aacatcagat gacgctcttg cactcggacg tgaaattggt ggaaaagaag gcttccttgt
    21001 agggatttcc tcagctgcag ctatctacgg agccatcgag gttgccaaaa aattaggtac
    21061 aggtaaaaaa gtccttgtcc tagcaccaga taacggtgaa cgttatctct ctacagcact
    21121 ttatgaattg taaccgtcca ataacgaagt atattgaaaa atctccagac tagagaactc
    21181 acggatagtt cctaatctgg agatttctta tttgcacttt tcttgtacaa ctttagtcca
    21241 tggtaaataa gcctctaaaa cctctttgtt tacgagagtt tccacgtttg gaagacattc
    21301 tagaagatag gatagatatt tctcactatt tataatggat tgaaataaga tatgaacaaa
    21361 tcgattagga catgatggta aagcgtaatc ccttgtttct cagctttccc agacaaaaaa
    21421 gtccaatagt aagtcagctg actatcactc tctagcaccc tataagaagt ttcatccgca
    21481 tgaagtaagg gctgagtcaa tagtctctct cgcaagaggt tatagagggg ctccaaatag
    21541 tattgactcg tcttgatatg ccaattagag atttccttgc gtgtgattgg taaacccatc
    21601 ttagcccaat cttcttcttg gcgataattg ggtaccttca gattaaactt ctgatggatg
    21661 gtgtgagcga taatagaagc tgagccaaag ctatgcgcta aaggggcttt aggaatagga
    21721 gctttcacaa gcttatccag atgattatct tttactcgtt atggaca
//
LOCUS       DBEJKC010000032        20384 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.032, whole genome shotgun sequence.
ACCESSION   DBEJKC010000032 DBEJKC010000000
VERSION     DBEJKC010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20384
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.032"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(358..1965)
                     /locus_tag="ACL3G6_001286"
     CDS             complement(358..1965)
                     /locus_tag="ACL3G6_001286"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HGR0545814.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAAAMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(2355..2942)
                     /gene="rpoE"
                     /locus_tag="ACL3G6_001287"
     CDS             complement(2355..2942)
                     /gene="rpoE"
                     /locus_tag="ACL3G6_001287"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HGR0545815.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(3070..3381)
                     /locus_tag="ACL3G6_001288"
                     /pseudo
     CDS             complement(3070..3381)
                     /locus_tag="ACL3G6_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
     gene            complement(3279..3695)
                     /locus_tag="ACL3G6_001289"
     CDS             complement(3279..3695)
                     /locus_tag="ACL3G6_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545816.1"
                     /translation="MKVNIVDLHPTQLYLSEKKLQDIQMLYQSAETNQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLKNHI
                     LPLWIGMVSFFGLKSRRRENGFQLGILHYLRIISPL"
     gene            complement(3723..4373)
                     /locus_tag="ACL3G6_001290"
     CDS             complement(3723..4373)
                     /locus_tag="ACL3G6_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGR0545817.1"
                     /translation="MKDKQTFLMKGSFALLLFVILGYMVKFYPETLVGFDQSIQTAIR
                     GDLPDYLTILFRSLTHLIDIPVIITWVVIIAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASFCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4363..4926)
                     /locus_tag="ACL3G6_001291"
     CDS             complement(4363..4926)
                     /locus_tag="ACL3G6_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0545818.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5091..5325)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5379..5882)
                     /locus_tag="ACL3G6_001292"
     CDS             complement(5379..5882)
                     /locus_tag="ACL3G6_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HGR0545819.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6075..6905)
                     /locus_tag="ACL3G6_001293"
     CDS             complement(6075..6905)
                     /locus_tag="ACL3G6_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR0545820.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(6890..8572)
                     /locus_tag="ACL3G6_001294"
     CDS             complement(6890..8572)
                     /locus_tag="ACL3G6_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0545821.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHCPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNLSIS
                     KGQVQLQNELAKETPALQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(8683..8931)
                     /locus_tag="ACL3G6_001295"
     CDS             complement(8683..8931)
                     /locus_tag="ACL3G6_001295"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545822.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVR"
     gene            complement(8938..9486)
                     /locus_tag="ACL3G6_001296"
     CDS             complement(8938..9486)
                     /locus_tag="ACL3G6_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HGR0545823.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(9501..10349)
                     /locus_tag="ACL3G6_001297"
     CDS             complement(9501..10349)
                     /locus_tag="ACL3G6_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HGR0545824.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            10537..11886
                     /gene="trkA"
                     /locus_tag="ACL3G6_001298"
     CDS             10537..11886
                     /gene="trkA"
                     /locus_tag="ACL3G6_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HGR0545825.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIETKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            11890..13329
                     /locus_tag="ACL3G6_001299"
     CDS             11890..13329
                     /locus_tag="ACL3G6_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGR0545826.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(13454..15133)
                     /locus_tag="ACL3G6_001300"
     CDS             complement(13454..15133)
                     /locus_tag="ACL3G6_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGR0545827.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGVIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QSISFVFLSLILVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEETSEIMPGELDE
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
     gene            complement(15203..16615)
                     /gene="lacG"
                     /locus_tag="ACL3G6_001301"
     CDS             complement(15203..16615)
                     /gene="lacG"
                     /locus_tag="ACL3G6_001301"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGR0545828.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGINMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKYNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKVGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            complement(16625..16969)
                     /locus_tag="ACL3G6_001302"
     CDS             complement(16625..16969)
                     /locus_tag="ACL3G6_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0545829.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEAYGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            complement(17137..19023)
                     /locus_tag="ACL3G6_001303"
     CDS             complement(17137..19023)
                     /locus_tag="ACL3G6_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HGR0545830.1"
                     /translation="MVIRVFDKQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRRDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKAFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGQMLWKKTRNYEELIEEYFSALYGENWQSVVEYLEKL
                     SIYSSCDYFNAIGSRQSDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWKNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            complement(19025..20347)
                     /locus_tag="ACL3G6_001304"
     CDS             complement(19025..20347)
                     /locus_tag="ACL3G6_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0545831.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEAFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
BASE COUNT         6288 a         4534 c         3523 g         6039 t
ORIGIN      
        1 tggattaaat taaaaaagta taatgtattg aatctataac agtacatctt gactgctaaa
       61 atatttctat aaattaattt gactttcctt atagagatgt tcacatctta tttcaattca
      121 tgatacaatc cagttcctaa aactttgcta gaaattaatt tggctttccg aattaatttg
      181 ttcagatttt atttcatttc aatatactga taaatccatt cactagcaca gggcaagagg
      241 gagtcgctat tgatttcaac ggtagcaggt acatacagag gactcctacc tcagatatac
      301 tgcaatatca tcgtatgcaa aaaacctctg agatttttct caaaggttct gattttgcta
      361 attgctgttc tcaaccgctg cagtaacaaa ggcagtgtag agttcttctg gtcggtttgg
      421 acggcttgac agttcagggt gatactgaca agctacaaag aatttatttt caggaatttc
      481 cacgatttct accaaacgat tgtctggaga aactcctgaa aagacaaaac ctgctgcctc
      541 aaactgctca cggaaggcat tattaaactc ataacggtga cggtgacggc gttgcaccac
      601 ttcttgattg tgataagcag cagcagcctt agagccacgt ttcaacttag acggataaag
      661 tcccaaacga agggttccac ccatatcctc aatatcaatc tgatcacgca tgatatcaat
      721 gatagggtat tttgtttctg gtgcaagctc tgcagaattg gcaccttcaa gacctaaaac
      781 gtgacgagca aactcgatac atgtcaactg cattcccaag cagactccca acattggaac
      841 atcattttca cgcgcatagc ggatggcttg gattttccct tctgtaccac gttgaccaaa
      901 accacctggt acgatgatcc cgtccgcatc agacaagagt tctgctacat tctctgctgt
      961 cacatcattg gcattgaccc aattgatttt aacttctgca tcattgacat agccagagtg
     1021 tttcaaggct tcgaccactg agatataggc atcttgcaac tccacatact taccaacaag
     1081 ggaaatctta acttgtttct tgaggttcat gaccttgtcc accatggctg accattctgt
     1141 catagccgct gctggtgcgt ctaatttcaa atgatcacaa acaatttggt ccatcccttg
     1201 tgcctgcaag ttcagtggaa tttggtaaag gtgttcaaca tccaacgatt cgataacggc
     1261 ttctggtgcc acatcacaga actgggccag tttattttta attccttgac cagctggctc
     1321 ttctgtacga ataaccaaca tatttggttg gattcccaag ccacgcaatt ctttgacaga
     1381 gtgttgggtt ggtttggttt tcatttcacc agcagccttg aggtaaggaa gcaaggttgt
     1441 atggatatac atgacattat ccgcacccac atctgccttc atctgacgaa gagcctctag
     1501 gaatggcaag gactcgatat ctcctactgt tccaccaacc tctgtgataa tgacatcaga
     1561 gtcggtcgtt agagcggcac gcttgatttt ttctttcaaa gcatctgtga tatgaggaat
     1621 gacttgaaca gttgccccaa ggtattctcc acggcgttct ttacgaagaa cttcactgta
     1681 aattttccca gttgtcacgt tggaatattt gttgagattg atatcgatga aacgttcata
     1741 gtgacccaag tccaaatctg tctcagctcc gtcatctgtc acaaaaactt ccccgtgctg
     1801 gtaaggactc atggttcccg gatcaatatt gatataaggg tcaaactttt gaatggttac
     1861 tttgagacca cgatttttca agagacggcc tagactcgct gccacaatcc ctttcccaat
     1921 agacgatacc acaccaccag ttacaaaaat atatttcgta gacatagatt cctctttcta
     1981 aaatgctcaa ggtcttgtta actacgaggg gatatagaaa acaagaccct actaataaga
     2041 ataatctggg acgactgcac cagattcaca actaatactc ttcgaaaatc tcttcaaacc
     2101 gcgtcaacgt cgccttgccg tagatatgtg ttcctgactt tgtcagtctt atctacaacc
     2161 tcaaaacagt gttttgagca gcctacggct agtttcctag cttgctcttt gattttcatt
     2221 gagtataaaa tacaagaaga taacttcttg aaaaaacaaa aatagctccc taagaactag
     2281 ggagccccga cctctaaaag aggtgcccaa acaatatgat acctaaaaat aggataattg
     2341 tcaatagcta actcttattc ctcgctggtt tcagcgtcgt catctgaaaa ctcgtcgtcg
     2401 tcttcgttga gatccacatc ttctcccaag tcatctggag cgatttcgtt gatttctgca
     2461 tcataagctt ccacttcatt tttttcatca tctggatttt catcatcgta tgaaagagct
     2521 ggatctgctt cgtatgcatc ttcgtcttct ggatcatctg cattgtagtc aatggcatct
     2581 gaatcaccat ccataaaggc attgacacgt tttttcttag cttttggtgc tacttcatcg
     2641 tcgtcatttt cttcaagagc gatgatttct tcgtcgattt cgtccacacc ataccatgaa
     2701 cgaagacccc atttgttgtc cccaagtgag atgaagctac cgtcaaagtt caactctgtg
     2761 tagaacagag gcaaagcttc gcggatatcg ctgtttgatg ttccaaggta gttttgaatt
     2821 tcgtttacaa gatcgctaaa atgcatctca tgatcgcgac cacgaagttc taatatagca
     2881 cgcgctacct caatcataga tagttcactt ttttcttgcc cagcaaatac ttctaattcc
     2941 aaagcgtttc tcctcattta tactactatc gccagagcga acagactctg acctcatttt
     3001 atcatttact ctttatttta cgataatttt gcggaatagt caaaggttaa gggggagaaa
     3061 gtggcaggat tagactaatt ccaatataaa actccttcct ttttctgttg ctccattttc
     3121 cacaaatcca agcgacttga aacacctcct agaagcatga ttgtaggtgt agatttcctt
     3181 gactctcaat tctttccatc cttttactcg agccaattca atcaaagcac ttagaatctt
     3241 ttttccaagt cctcgatgtt ggtaagcgga attcccaatc acaatgggga gattatcctg
     3301 agatagtgta atatccccaa ttggaaacca ttctcccttc tccttgactt caatccaaaa
     3361 aagctcacca tgccgatcca aagaggtaag atatgatttt ttaaatcaaa aacagagtaa
     3421 atctttcttt cctcgcaagc ttgcgcatag agatgatata gttcatcacc accatctcta
     3481 tcccactcag cagaaatcgt atcccgacct gccaataaag cctgataagc cctgtgatgc
     3541 ccatctgtaa tcagcaaaca atctccaaag gcaagaatac tgattggatc gacttggttt
     3601 gtttctgccg actggtaaag catctgaata tcttgcaact tcttttctga taaatatagt
     3661 tgagtcggat gaagatctac tatattgact ttcatttctt tctcctaaag ggaattcgat
     3721 actcacttct gtttgccttt aaatcgccat tggaagcgga gcttgtcata gaagggaaac
     3781 tcgataaaca agactcccaa acccacacag aaactggcaa gaacatctga tgggtagtga
     3841 actcccagat agactcttga taccagcaca ctgactaggt agaggccaag gacgatttgt
     3901 acgatttttc tccagacctg atctttaatc cgctgactaa gaataacaat caaagtccct
     3961 accatcagcg ttacagctag agaatgccca cttgggaagg aaaatccctt ctcctccacc
     4021 agatgtaaga tagctggtcg tgggcgctgg tagatatttt taaaggtcac gattaaaaga
     4081 cctgccaaag ccagatttcc cagcatgaag aaactttcta tcttccatcg cttacgataa
     4141 aagacaaaag ctataatgac aacccaagtg ataatcactg gaatatcaat cagatgtgtg
     4201 agggatcgaa aaagaatagt caaataatct ggtaagtctc ctcgaatggc agtctgaatc
     4261 gattggtcaa aaccgaccag cgtttcaggg taaaatttga ccatatagcc aagaataacg
     4321 aaaagtaaaa gggcaaaact gcccttcatt aaaaatgttt gtttatcttt catagtgttt
     4381 taaggttggt ttcaaaagga cgtacaacaa ccagaatgaa acggaaaaga ttacaccctc
     4441 aatcaagtta aaaggtaata ccatggtcat taggtagttg gaaagtccca aaatttttcc
     4501 aatatcaaag ttagcaaact tagcgtacaa aggaacagca taaacatagt tgagaaccaa
     4561 catggccaag gttaaaccaa cagttccagc tagagagcct agtaggaaac gaagggttgt
     4621 ccgttccttt ttccaaatca aagcaaatac gatgacaaaa actcccaaag ctacgatatt
     4681 catcggcaaa ccaatgtaag tattcactcc ttggctgtta agaagcaatt tcaatagtga
     4741 gcgaagcaag agcactccta gagcagcagg caaatccatg accaccagac ccacaaggac
     4801 tggcaagata ctaaattcga tcttgaggaa agatgccgct ggtaaaagcg gaaagtcaaa
     4861 gtacatcagc acaaatgaga tggctgatag aattgcaatg gtcgaaagtc gacgtgtgtt
     4921 tgtcataaca ggttcctcca attttctata aaatcagaag aagttggaaa ggattcctct
     4981 atctattctc actttttata tcccaaaagt tccctcttac tctattaaag aaaaacaaag
     5041 caagtggtta caatccggct ataaatctat caaaacagac aaagctattc tttcgtcttc
     5101 tcccatccag actatactgt cggttgtgga atctcaccac atcagcttgc gctcgcggac
     5161 ttctttaaag agaaggaaat agagattttt cttttagact aggcgacaag ctgtaggcat
     5221 aacttctggt taggcaaagc ttgtcaacaa agtataaaag gaaaagatca tttcctagtt
     5281 aaagtcaccg ccggtcggga atcacaccct gccctgaaga ctcttttatc ataacaaaaa
     5341 acgcttgcaa gcgcaagcat tttgttcatt ttcatttttt atttcaattt atccacttca
     5401 taggtatgga cgagctcaag acctgcaaag ttctgctggc gaagagcctc atagacaatc
     5461 atgcagacgg tattagacac attgagactg cggacatgtt catcattcat gggaatacgg
     5521 agagccttct caggatgttc tcgcataaaa tcttcaggta agcccttgtc ttcacgtcca
     5581 aagagaaaat aatggtcctc gtcagtcgat aaatccacct cagaatagac tttttccgcg
     5641 aatttcgaaa tcagatagag ttttcccttc atctgagata tgaaatcttc caaactctcg
     5701 taaaaataaa tctctagctt atcccagtaa tccaatccag cccgcttcat cttgcggtca
     5761 tcaataggaa agcccatagg cttgatgatg tggaggggag aattggtcgc agcgcaagta
     5821 cgcgcgatat tgcccgtatt ttgtggaatt tgaggttcaa ataatacaat gtgatttgtc
     5881 atgacttgct tcctttcacc attgcaaaaa aatagccaca ctgcccggag tcaagctcag
     5941 caaacagcgt ggttaaggca tcgttaactt acctcacaac aggtttgaag taaatcagcg
     6001 aaactacttt cttagtataa cactttcaga atcattgtca atagaaatga cttgattttt
     6061 tcaatttttt caagctattt ccaagggttg taaaatcgtc cctgattctg caagataagt
     6121 agtaaactaa ctactaaaaa caaggttgcc aagagcaagg taatatagtc tccttttttc
     6181 aaggcctgat aactatacca tgtgcgtttt ttctctttcc caaagcggcg aagctccatg
     6241 gcagtcgcaa tggtatcaat gcgttctagc gagctaaaaa tcaagggcgt aataatgagc
     6301 agattgcctt tgattcgttg cataagagaa gctttcttgg ataattccat cccacgcgcc
     6361 tcctgagaca tcttgatagt aaagaattct tcctgcaaat ctggaatata gcgcaaggtc
     6421 aggctgacag aataagcaat cttatagggc acaccaattt gatttaaact ggaagcaaac
     6481 tgactaggat gggttgtcat caaaaagata atagccagag gaatggtgca aagatactta
     6541 atggccaaat ttagcagata aaagagctcc tggctggtta gagtgtagac accgattccc
     6601 tgccaaatca cacttctctc tccataaagt ccaaccccat actcgggaga aaagagatag
     6661 accatcaaaa cgtttaaaac ggcaaatacc gtcgcaaaaa cggctacaaa ggaaacatct
     6721 ttaaagcgaa tttctgataa atagaggaga aagactgaaa agatggcaat cagcaagagc
     6781 attctggtat catagctaat catggccgcc aatgatacca gaatgaaaaa gagaagtttc
     6841 ccagctcctg acaagcgatg aatcacagta tctctatgct ggtaaccgat taatttagct
     6901 tgcatccctc tctcctttct ttgtaaaatg ccgttaaatc cagtggatcc acatctagtt
     6961 tcttagccaa gttaaagatg gaggtttctt ttagattggc ttttactaac agctcaggat
     7021 cgctcaacag actggctgga acagtatcgg caatcaattc tccatccacc atgacaagga
     7081 cccggtctga ataatccagc atcaattgca tatcatgggt aatcatgaca atggtatgcc
     7141 ctttttgatg taactcttcg agaaattcca taatctcagt atagttcttc tgatcttgac
     7201 ctgcagtcgg ttcatctagg agaataattt cagctcctaa gaccaaaatt gaagcaatgg
     7261 tgacacgttt tttctgacca aatgacaggg cagaaatagg ccaattacgg aattcataaa
     7321 gtccacagat tttcaaggtt tcatatactc tcgtttcaat ttccttctca tccacacctc
     7381 gcaaacggag ccctagagcc acctcatcaa aaatcatatt ggttgaaatc atttgattag
     7441 gattttgtag cacatatcct actcgttccg cccgctctgc aacagaatcg ccttttatat
     7501 cctgtttttc ccaaagatag cgtccttccg tctgaataaa gctacttata gccttggcta
     7561 gagttgattt ccctgctcca ttttttccga caatagcaat cttttcaccc tttttaatat
     7621 ctaaatgtag ggattttaaa atcggtctat catcataaga aaaagatact tcctctagtc
     7681 taaagagtga ctgcaatgct ggggtttctt ttgccagttc attctgcaac tgaacctgac
     7741 cttttgagat agacaagtta tccagattcg ctaattgttc ttccttgact aaatccacac
     7801 ccaattgacg gagagtggtg agataaaggg gttcgcgaat tccattttgg gtcaacaaat
     7861 cagtcgccag taactggtca gggctcccat taaaaaggat acgaccatcg tttatcaaga
     7921 caatccgatc cacagggcaa tgcagaacat cctccaaacg gtgctcgata ataagggtcg
     7981 tcgtcccctc ctccttatga atctggtcaa tcaattcgat aatatcctga cctgacttgg
     8041 gatcaagatt ggcgagtggc tcatcaaaca agagaatcgg actttcatca atcaagacac
     8101 cagccagact gactcgctgc ttttgtccac ctgacaaatc ctgagggcgc tgatccagta
     8161 aaggaagaag gtccagcttt tcagcccatt tataaacacg acctttcatc tcatctaggg
     8221 ctgtcacatc attttccaga gcaaacgcca aatcttctgc cacagacaag ccaataaact
     8281 gcccatctgt atcctgcaaa actgtgctaa ccagatgaga cttatcatag atgctcatat
     8341 caaaggctgt ttgacccttt atcaaaaatt ctccatatgt ctgacccttg taaatattgg
     8401 gaataatccc attcaaacac tgacccaagg tagatttacc tgatccagat ggtccaacaa
     8461 ttaagacttt ctctcccttg taaatggtca agtctatccc ttgcaaggtc ggttcttgtt
     8521 gtgtttcata ccggaaagag aaatccttcc actcaattat agcttctttc atcttactct
     8581 cttcattcgc ttcttagact tctattttat cataaatcaa gcccttcttg cagtctctcc
     8641 tattaaaatc ttagcgccaa aaagattcct atcctagctt acttacctaa ctaatctata
     8701 aacatcgaaa aagactagtt gcccagcctt ccccatcatt ttatactctt cgaaaatctc
     8761 ttcaaaccac gtcagcttcg ccttgccgta ggtatggtta ctgacttcgt cagtttcatc
     8821 tacaacctca aaaccatgtt ttgagctgac ttcgtcagtt ctatccacaa tttcaaaaca
     8881 ctgttttgag caacctgcgg ctaacttcct agtttgctct ttgattttca ttgagtatta
     8941 gtcctttttc aaacttcctg cacgagtttg ggttcctgca taggcaagta agagaagagt
     9001 tcctgcaata gctacagata caccattggc aattcccgca acaatccctt gtgcaaatac
     9061 tttttctgcc gcttcttgat aaatcacaac atctccaagt ggtgccaaga caccccaaac
     9121 aagggcattt gcaagtagtt gaatgaggtt aaaaataaga atatctttcc agtcaaaaac
     9181 accattgatc acgcgaacgt actttctaaa aagtcccaca actaaaccaa agagtccgct
     9241 agcgataatc caagtccacc atagaccata accagcaaga gagtccttga ttgcatgacc
     9301 aatcaacccg acaagcaaac cgataatcgg tccaaaaata atagaaagta gcgcttgtac
     9361 cgcatactga agctggatgc ttgtatttgg aacaggggtt ggaatgttga tcatcccgat
     9421 gacgacaaag agggcagcgc caattccgac agcaacaact tgtttaattg taaatttaat
     9481 ttccatacta ttctcctatt ttatccttct attttcttta tttcaatggt ccaagatgaa
     9541 ccgacaccta cattataggc cttggcaaag gaaccttggt tgatagccaa acctaaacga
     9601 tagagagagt tgatgtaaag gatgggttgc ccaattctca catctgcaaa tgatttgcca
     9661 tagacaacct gattttgata gaccagcata tcagcatgat agatggtcac ttcaaaacga
     9721 tcaccaaatt ctggttccag cttgtaaaat tcttcccgtg tgatagaggt ccaaagcgaa
     9781 ccgaaacgca catccagaat atcaatggct cccttcacca gatgatcttc tatgatggtc
     9841 gctacgactg gaagctctac aatctgttcc acactgagct ctggccctac ttcctcaaaa
     9901 gtaatgtgac cactggccag tttagcacca gtataggcat agacatcacg accgtggaag
     9961 gtataagaat gctctgtgtt ttgacgccta ttggccacct cagaaatctc acgaatggct
    10021 acaatgccaa cgtgtttctt gataaaggaa agcgtcccat tatctggcgt gacaatgtat
    10081 tgattttttg cagtcttggc aactacactc ttacgtttcg aaccgacacc tggatcgaca
    10141 accgatacaa acgtcgttcc ctcaggccag taatccaccg tctgaaagag acgatagctc
    10201 ccctcaaaaa tattataagg cgtgatatcg tgcgtcaagt gatggatttt taaggttgga
    10261 gactcttcta aagccactcc aatcatagcc gataccgcac catcaaccag accaaagtct
    10321 gattgtaata ccagtaaatt attattcatt ttatctcctt gtatatcctt tatcatacca
    10381 tatttcagag aaagtcgcta atagctattt caattggtta gggtatagtt ttaccttata
    10441 gcgaattttc actaaaagct cttgttatta gctagtaggt gcattttttc ttgaaaaagg
    10501 gtatgatagt tacatcatga aaaagtaggt tttattatga aaattatcct tgtcggaggg
    10561 ggaaaagttg gttttgccct ctgtcgctcc ttggttgcag aaaagcatga tgttttgctg
    10621 attgagcaag acgaagctgt tctcaatcat attgtcagtc gctttgatat cattggtatc
    10681 cttggtaacg gggccgattt tgccattctt gagcaagcca gcgtccaaga ttgtgatatc
    10741 tttatcgccc tgactgagca cgatgaagtc aacatgattg cagcagttct agccaagaaa
    10801 atgggagcta aagaaactat cgttcgggtg cggaaccctg aatattctaa ctcttatttc
    10861 aaggaaaaga atattctcgg tttttctctt atcgttaatc ctgagctctt ggctgcccgc
    10921 gctatcgcga atatcattga cttccccaac gccctgtctg tcgaacgctt tgctggtgga
    10981 cgcgttagcc tcatggaatt tgtcgtcaag tccaccagcg gtctttgcca aatgcccatt
    11041 tctgattttc gtaaaaaatt tggtaatgtc attgtctgtg cgatagagag ggatcatcaa
    11101 attatcattc caagcggtga catgactgta caggataaag atagaatctt tgtcactggt
    11161 aaccgtgtcg atatgatact cttccataat tattttaaat cacgcgccgt gaagagcctt
    11221 ctcatcgttg gagctggtag aattgcctat tatctattag gtatcctcaa agatagtcgt
    11281 atcgaaacca aggttattga aatcaatcct gaaatcgcta gcttctttag cgagaaattc
    11341 ccaaatctct acatcgttca aggagatgga accgcaaaag atatcctgct ggaagaaagt
    11401 gctcaacact atgatgccgt tgcgactcta acaggagtcg atgaggaaaa tctgattaca
    11461 tctatgttcc ttgacagggt aggtgtacag aaaaatatta ctaaggtcaa tcgtaccagt
    11521 ctcctcgaga ttatcaatgc gcctgatttt tcaagtatca tcacacctaa aagcatcgct
    11581 gtagatacga ttatgcactt tattcgtggt cgagttaatg cccagtattc agaccttcaa
    11641 gccatgcacc atctagccaa tggccaaatc gaaaccctgc aattccatat caaggaagcc
    11701 aataaaatga ctgccaaacc tctttctcaa ctgaaattga aaaaaggggt tcttattgca
    11761 gccattattc gaaagggcaa gactattttc ccaactgggg aggatatgtt ggaagttgga
    11821 gacaagctcc tagtaacaac cttgttgcca aacatcacca agatttatga cttgattgcg
    11881 aggtaagaaa tgaataaaag tatgattcgt tacctccttt caaagttact tttgattgaa
    11941 gctgttctcc tcttggttcc tgtggctatc gctgtctatt accgtgaatc gagccaagtc
    12001 tttacagccc tcttttcgac catagggatt ctcgtattgt taggcggttc agggagttta
    12061 cagaagccaa aaaatcaacg gatttatgcc aaggagggag tcttgatcgt tgccctctgt
    12121 tggatccttt ggtctttctt tggtggtctc ccctttgtct tttctgggca aatccctagc
    12181 gttattgatg ccttttttga aattagttct gggtttacaa ctactggagc aagtattttg
    12241 aacgacgttt cggttctcag ccgttccctc ctcttctggc gaagttttac ccacttgatt
    12301 ggagggatgg gagtgcttgt ttttgcactt gctattatgg acaatgccaa aaatagccac
    12361 ctagaggtga tgaaggctga ggttccaggt cctgtttttg gcaaggttgt atccaaacta
    12421 aaaaacactg cccagattct ctatctcctt tatctagctc tcttctccct ctttgtcatc
    12481 atctattatc tagctggtat gcctctctac gatagttttg tcattgctat ggggacagcg
    12541 ggaactggag gctttaccgt ctataacgac ggaattgccc actatggcag ctcactgatt
    12601 acctatctgg tcagtatcgg agttctggtt tttggggtaa atttcaacct ctactactac
    12661 ctcatgctcc gtcgcatcaa ggccttcttt ggtgacgaag aacttcgggc ttacttggtc
    12721 attgtactgg tttctacagg cttgattagc ctcaacaccc tctacctcta cccagggttt
    12781 tcaaagagct ttgaaatgac cttcttccag gtttccaaca tcattacaac aactggtttt
    12841 ggatatggag atattaccaa ctggcccctc ttctcccagt ttatcctcct tttcctcatg
    12901 gcaatcggtg gctctgctgg atcaactgca ggtggactca agattattcg aggcctcatc
    12961 ctttcaaaaa ttgccaaaaa ccaaattttg tcaatcctat cgccccaccg tgttttgact
    13021 ctccatgtga atcaaacggt gattgataaa gatacccagc ataagattct caagtacttt
    13081 gtcatctatg ctatgatttt gctagcgctt atctttattg tcagcctaga tagcaatgat
    13141 tttctggtcg tgaccagcgc tgtctttagc tgtttcaata atatcgggcc tattctagga
    13201 accacttcta gtttctcaat ctttagtccc atctcaaaaa ttctcctctc ctttgcaatg
    13261 attgcagggc gcttggagat ttacccaatc ctccttctct ttatgaaaag aacttggtct
    13321 aagagataaa atacaaaatc cctcttttta caattgtgaa agagggattt ttatattaaa
    13381 aagggggaac gtttttaaat ccaagcctgt ctgtaagcaa agttcttact caaataaaag
    13441 atggaaaaac ttactacaca gcttggtaat gctccaatac aaattgtaag gctttacttg
    13501 gattctttgt taaatgaata tattccattc ctctggtagc aactatctga atacctaatc
    13561 tttctgcatc caccttcatc tctctataat aactccgaac ttgtggagcc agaataatta
    13621 aatcataaac acccataata tcataatgag ctccgtacgc tcctgaattc gcaatcactc
    13681 taacttctgc taattgagcg ccctcgttaa ttgcattggc taattgcgca cttgttccag
    13741 accctgcaca aagaaccagt actttcaact ccttactttt tatttcatct aactcaccag
    13801 gcattatttc acttgtctcc tcctctaaaa taatatcatt tgagcttgca acatcttctt
    13861 tcatcagtaa ctgtctatca tacgctctac agaatggcaa ataaatcaat atgtcgacaa
    13921 ctaaaatcaa agataaaaat acaaaggaga tagattgaaa attcgttcca attaacaatc
    13981 ccaagggacc aggaaaggcc caaggtaact ggatataaaa tccattcatt ccaaagaaat
    14041 caataaagac ctttcctaga aatacattca ctggtggagt catcaaaaaa ggtacaaaaa
    14101 gatagggatt caaaataact ggcataccaa atagaagagg ttcattcact gcaaataaaa
    14161 caggagtaat tgtagcttta cctaccgatt ttaattgttt agaccgcata aagaaaatca
    14221 aaataaatgg tacaacaaag gtagcccccg ttcctccgat agcagcgata taatttccga
    14281 aattaggcgt taaagaatga taaggaaact gcccatttgc aagaagttga gcattctctt
    14341 ccatattgct cagttgtaaa gctgtaacag caggtaagac aatagatggt ccatgaattc
    14401 caacaaacca aagcaaagcg cacataaacc aaatcaacat catagcagga tatgattctg
    14461 cccccttaaa aataggagtc aatagttgtt gaaatacttg ggcaaaagga acatctaaac
    14521 taaaccgaga tacaatatct aacaaaccac taataagtaa aacaaaagaa aaaggaaaaa
    14581 tatctctaaa agcttgtgat atagccccag gaacttcctt aggtaaatga atagtaatgt
    14641 ctcgcttaat acagaatcgg taaacattta cagtaataaa ggcactgaca aacgaagtta
    14701 tcaatccttg agatcctaaa tagtttgtcg acaaacttgt agatcccgtt ttctcatcaa
    14761 ctacaagcgt tacagttaat acaagatagc cacatatggc cgccaacatt gcagaagtat
    14821 catttattac ctttccagga ggcatttttc tattaacatt tccagccaat gactttgcaa
    14881 ctgtccctga aacaataaca cccaaaactc ccatggttag catatacact ttcctcatcc
    14941 aggcaatagc tggactcggt aactctactc cgaaattttt aggaatcata ataataatca
    15001 tcaaaaagct tgaaaacata attaaaggca tagtagcaat gaatccatct ttaatagcca
    15061 tcatataatt attagtagaa attttttcaa atttcccttg ttgcttttca atggcagcga
    15121 ctaacttatc cataaaaact cctcctgtaa aaaatttaag ctcatagtta aaatatatta
    15181 aacatcagtc aaatcgctaa ccttaattcc gttttagccc ttttacccaa agagcacttt
    15241 tcttaatata tctcttctgt gtttcataat caacaaagaa aagaccatat cgcttattgt
    15301 agccattcgc ccaagaaaat tgatcttgca aagaccatat aaaatagcct tgaatattga
    15361 ctcccctatc tcgagcctct aaaactttgt gtaaatgttg ctcaatataa cggattcttt
    15421 tactgtcatc aataatatca ttctcgccct ctggcttaac ctctttaagg gctgtaccat
    15481 tttcagttaa ataaatgacc ggatgttgag gatattcttc tttgatacga agcaacatat
    15541 caaataaccc ttgaggataa atattccaat cccaatctgt tgtcggaata ccaggctttt
    15601 ttacaaattc acctagagca tttaatttaa aagaagactg tccttttatt cctgttgaat
    15661 taaattcttg tctattttca cctttgtatt cacgaataaa ttctgaacga taataattca
    15721 tcccaaacat cgtattaaga ggtgcagctc ttttcataat ttctaaatca ccatcttcaa
    15781 taataaagct agaattatta gcttccaata tttgattcaa gtgaaaaagc gtgtcatcac
    15841 tgtagtagcc caaaaaagtt ccatctaata gaaatttatt attataaaca tcataccgtt
    15901 tagctgccaa aatattttct ttttgcccat caataggata gcctggcttt aaagcatgaa
    15961 tacaacctac ctttccctca atccctaatt gatgaaattc gaggactgca agagcatgcg
    16021 ccaacaacat gttatgattt gcttgaattg cttcagataa ttgaaaatgg tgattcggag
    16081 gaaactgacc tcctatgtat tggcctgcag caagagacat cagttcattg attgtaaacc
    16141 aatgcttgac ttctgtaaat tcttggaaac aaaagcgagc atatcgtatg aaacgatcaa
    16201 tattctctct attcaaccaa tcccctgttt ctaacatttt ctgaggcgaa tcaaaatgat
    16261 gtaaagaaac aaacggaatc acattatatt ttaagcagga ctgaaagact ctatggtaat
    16321 aacgaacagc caatatattc ggctccccat ctatatcagg aaatatacga acccaagaaa
    16381 tagataaacg caaagcctgc aaaccatgtt ctgccgccaa agctatatcc tcttcgtaac
    16441 gataataaaa atcactagct ggatctggta agaacggact attttcttgc aaataaacat
    16501 cccacatatt tattcctttg ccatctaccc tagttgcacc ctctacttga taagcagcgg
    16561 tagcagctcc taataaaaac tccttcggta aggctttaac ctgtaaattt tccatgacta
    16621 atcctcattg caaaccaata tgttcttcaa tctttcgaat tcgttcatat tcatcaataa
    16681 aaaactttac ctgatcatac aatagcatcg ttgtcatcaa agtatcttga ccatgaatca
    16741 tgataaaact cacttcaaaa ttatctccat atgcctcctc cgctaataaa ttagtctgtt
    16801 ctcgatgggc agacactatt gagtcgtttg cagactcaac caattctctt gcctgttcaa
    16861 aatatccatc tctcgcaaac gccaaagcat ccatcaaatc tgaccttgca tctcctgcgt
    16921 aagcgacaat tgtaaaacca agcatattta tttcttcttt tgatttcatc tttcttcctc
    16981 ctcaatcttg aaccatcttt tacacatcat tattaaaatg acttcgctac gatacaaata
    17041 gaaagtcgac cctaaatatc ttaaaaatcc ttaaatttca taatatttag gatcaatctt
    17101 ctctgaatac cttggttcat tttctagact tatgatttat aagtggaaac cagcgtaatt
    17161 ttttgctact tcaattacac gataaacatc caaattagat tggaatagca gttcgtgccc
    17221 acggatataa ttcaacacat ttttccactc atcttgagct tgccttgttt ttccggttgc
    17281 ttgaagatat aaagccttcg ccatcttgac aacatattca cgatgataac tgagctgttt
    17341 ccattcatcc ttttgactat ttaataactt agaaatattt tcctcaataa ttggtaaaaa
    17401 attatcagct agattgtaag ctatataata atgattcgct aaaacatcac tttgacggct
    17461 gccaattgca ttaaaataat cacaagagga ataaatggat aatttttcta aatattcaac
    17521 aacagactgc caattttccc catacaaagc agaaaagtat tcttcaatca attcttcata
    17581 atttcttgtc ttcttccaga gcatttgccc catgacataa ttaggaaaat tatgagggaa
    17641 tccggcacgt aattcttgac acgaaatgta cccgttcaaa tgtaggttgg aaagataaga
    17701 tacatctctg taaatagttt gactaatttt catatagcct aaatcgccat aatgagcacg
    17761 ccctaaagga tagtcatata cgaaactatc tcctttaaat gctttttgcc actcaaaaag
    17821 ataagataaa ttttcctcaa gagaattcgg aagtataatt ttattacgca gataaggttt
    17881 aggcgtaggt atggaattgt caaaatctac atctgcataa ctcatttcaa atgttcttgt
    17941 aatcggtgca aacatcatgg taaagcgttc aggattatct aatttttctt tctgaggtgc
    18001 ccataacaac tcatgataaa gcagaaaaca aatctttgta tctaatccct cactcgttaa
    18061 agccctatcc aattgattga gaatacgaat atactgatcc gaaaccaatt cttgtctaca
    18121 gttttcgcat tcacaaatat tattacgagc atccgacaac catacatgta agtagttaac
    18181 atcaggtctt ttcttggcat aatccttgat aatttctacc atcttatcag ctacatctgg
    18241 atttgaaaaa tccaggctgg ttaaaatcgg agccgtatta aacaattctc gtttcccgtt
    18301 tatttcagcg acatagggtt tcttctcctc tgaaatacta agacctgatt cccagccaaa
    18361 ttttgaagag taacctaaaa cttcacctgt ccatccatga ccaacacgat gatgaataag
    18421 acctcttttt tgcaattctt tatccaacct atcactcaat tcttgtacta attcatttga
    18481 aaattgttct ttatttagat atggattaaa ttcatgttca taccaacgtt tcaaaaaaga
    18541 gtagggattt tcaaactgga tgaaaaaact gttcatccca atcttaggta gccaatcaat
    18601 gaaatctagt atattttcaa atgaatccgc tccctctata catactcccc tatgatagta
    18661 actggctgtt tcatctatag atagctgttt atctaaaaaa tcttcaaatc gtaactctgg
    18721 aacaaagtca tgtccgcgcc ctggtctagt atacacaacc ccaaattcat gaaacattcg
    18781 gtaaattcca ataagtaaac ctacaattgt attagactca attctcccct tacccttgtc
    18841 taatgagata agaacatggt ctcttctatc ctctttattg actaatccta caaaaatatc
    18901 cgcttccttc tcctcgacaa gttctatgtc agtcttaaag acccgattta tatagtaact
    18961 taattcctct aaggcaaagc tagaataagt atttttctgc ttatcaaata ctctgataac
    19021 catcttattt ccctccaaca gtagcttttt ctttttcaag attgcgttta tctgcaattt
    19081 tgaagaatgg ataataaatt gctacagaaa ccaaaatcaa aacaacttgt aatagagctc
    19141 ctcgccaact agctcctgtc gcaaggaagc ctcctatgat cggtggcatt gtccacggaa
    19201 ggattacacc tgttgtatag ggtactaatc ctacagccat tgatacatag gtaattaagg
    19261 cattgattgt aggagtagca ataaacggaa tcagcataat cggatttaaa actgttggaa
    19321 acgtaaatag aatagctgta ttgatattaa aaatagacgg tataatagct agcttaccta
    19381 atgttttatt cgcacgactc ttactaaata ggaagagaca aatcgcaaga ccaatagtcg
    19441 ctccaccgcc accaataaat acaaataaat ctttaaacgg taatgtaata atgtgttgga
    19501 gtgtttgtcc tgcagccaca gcttcttggt tttctgtagt aaattgtaac caaactgggt
    19561 ctacaaaagc atttaaaact tgtcccccat taactccaca gaaccaaaag aatgagttta
    19621 caataacaca tagaatcata cctggaagcg ttcctgcaat taacttaagc ggtgttccaa
    19681 caattgcacc taggagtccg ttgagacctc ctgcaactcc tgccgcttca agacctttta
    19741 agaccagagc ccacaaaaca aaagtagtaa agccaggtaa aagagctgaa aatgatttac
    19801 ttaccacatc tgggacacca cttggcattt ttatcgtaat tccgcgctgg ataaacatac
    19861 gataaatctc tgctgtaacc aatccaatag taatcgccat aaacaaagaa gatgcattca
    19921 gactagaaaa tggtattgcg ccgccaaata actgcttgac ctgctcccca tttttatcat
    19981 aaaccatact cgaaaaacga ggtgccatca atacaaaact ggataaggct atgatccctg
    20041 ccgacggacc atctgtacca tatccttccg acaacctgta ggcaataccg aaacaagcga
    20101 ccaaggagat aatcgctact gttgactgat tcatagttgt caagatactt agcaatccaa
    20161 cactattcag ccaatttgta aaagcctctt gaggccaact gattagaata agaaataaag
    20221 agccgactaa aatcaaaggc attgccatca taaatccttc acgaatagct ttcaaatgcc
    20281 gttggttgcc aactttttca ccaaacggag cgacttttgt ttctaaaaac gctaaaatat
    20341 tgttcatcac cggaactcct ttttttattt tttataaatt aaat
//
LOCUS       DBEJKC010000033        19821 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.033, whole genome shotgun sequence.
ACCESSION   DBEJKC010000033 DBEJKC010000000
VERSION     DBEJKC010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19821
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.033"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            390..737
                     /gene="ssrA"
                     /locus_tag="ACL3G6_001305"
     tmRNA           390..737
                     /gene="ssrA"
                     /locus_tag="ACL3G6_001305"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(849..936)
                     /locus_tag="ACL3G6_001306"
     tRNA            complement(849..936)
                     /locus_tag="ACL3G6_001306"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(900..902),aa:Ser,seq:gga)
     gene            1098..1838
                     /locus_tag="ACL3G6_001307"
     CDS             1098..1838
                     /locus_tag="ACL3G6_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0545832.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPAVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            1835..2746
                     /gene="pfkB"
                     /locus_tag="ACL3G6_001308"
     CDS             1835..2746
                     /gene="pfkB"
                     /locus_tag="ACL3G6_001308"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HGR0545833.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAELIKETYGKVEVEKR"
     gene            2743..4695
                     /locus_tag="ACL3G6_001309"
     CDS             2743..4695
                     /locus_tag="ACL3G6_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGR0545834.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALSVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YVAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            4832..7084
                     /locus_tag="ACL3G6_001310"
     CDS             4832..7084
                     /locus_tag="ACL3G6_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HGR0545835.1"
                     /translation="MERKEAIQRMLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGS
                     LAYLAIFGLLIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGT
                     MAQVVTDLTGFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWS
                     VYDIAEFFSRGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPP
                     VDMETGEILTEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAK
                     EALEYKLPSLQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVT
                     KYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFR
                     ELWEQSQTKAENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASI
                     LMKARPDQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYEL
                     FAKVGVRNIAGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRL
                     GQKARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLL
                     GRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGE
                     FSDGDAGGDPLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAE
                     GTKPRKVLQQ"
     gene            complement(7237..7662)
                     /locus_tag="ACL3G6_001311"
     CDS             complement(7237..7662)
                     /locus_tag="ACL3G6_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6556 family protein"
                     /protein_id="HGR0545836.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQPNTPTSENNTQ"
     gene            7800..8942
                     /locus_tag="ACL3G6_001312"
     CDS             7800..8942
                     /locus_tag="ACL3G6_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGR0545837.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHSLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRPDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDGVQALTKIPTEKYLTERVDFATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            8951..10165
                     /gene="thiI"
                     /locus_tag="ACL3G6_001313"
     CDS             8951..10165
                     /gene="thiI"
                     /locus_tag="ACL3G6_001313"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HGR0545838.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            10300..11105
                     /locus_tag="ACL3G6_001314"
                     /pseudo
     CDS             10300..11105
                     /locus_tag="ACL3G6_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            11127..11866
                     /locus_tag="ACL3G6_001315"
                     /pseudo
     CDS             11127..11866
                     /locus_tag="ACL3G6_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            11879..13045
                     /locus_tag="ACL3G6_001316"
     CDS             11879..13045
                     /locus_tag="ACL3G6_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGR0545839.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            13553..15046
                     /locus_tag="ACL3G6_001317"
     CDS             13553..15046
                     /locus_tag="ACL3G6_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGR0545840.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            15059..16168
                     /locus_tag="ACL3G6_001318"
     CDS             15059..16168
                     /locus_tag="ACL3G6_001318"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0545841.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHL
                     RINSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLA
                     LQNEFADFVVQVDKSQFACEIAIKVWRNSLKFSII"
     gene            16198..19483
                     /locus_tag="ACL3G6_001319"
                     /pseudo
     CDS             16198..19483
                     /locus_tag="ACL3G6_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
BASE COUNT         6032 a         3567 c         4332 g         5890 t
ORIGIN      
        1 atcgatttga ctgtcctgat ctattcgtcc tattcttatt tcattttact atattttggt
       61 gcaataagtg aaaagtagtc cgaataatat aaggattgat tttatagttt ttaaactcaa
      121 atgaattaaa ataaagagag tacgaaaatt ctcatctgaa agtattttag aataattttc
      181 ttcgtgaatt tcttcaaaac agatagcttc atcttaggta tgtgttaatt ggatttcgta
      241 agctctattt acaatcgtaa agttatgcac tgagaaagtt gtagttagtc ttccagtttg
      301 ctaaatttct cgaatagtat cttttttagg tatgtgattt ctttttgcat ttttgagtta
      361 gataaggtat aatggtttta ttgtcttttg gggtcgttac ggattcgaca ggcattatga
      421 ggcatatttt gcgactcgtg tggcgacgta aacgctcagt taaatataac tgcaaaaaat
      481 aacacttctt acgctctagc tgcctaaaaa ccagcaggcg tgacccgatt tggattgctc
      541 gtgttcaatg acaggtctta ttattagcga gatacgatta agccttgtct agcggcttga
      601 taagagattg atagactcgc agtttctaga cttgagttat gtgtcgaggg gctgttaaaa
      661 taatacataa cctatggttg tagacaaata tgttggcagg tgtttggacg tgggttcgac
      721 tcccaccggc tccattattc ctttgcattc ttttgctaaa aagggagtca caaacagacc
      781 ctattttaaa aaaaggatag aaaaaaggat acaacatttg tcgcatccta aaaataatct
      841 tttttccacg gaagacatgg gattcgaacc cacgcacgct attacacgcc taccgcgttt
      901 ccaacacggc ctcttaagcc tcttgagtaa tcttccaata cttactcaaa tagtctacca
      961 taaaggctct tatcttgcaa taaaaattct agaaatatga aaaatgatag attttgaaag
     1021 aaaatgataa aaaatgcttg acttcgaaag aaagtatgat agaatgaata gtgtaaacga
     1081 taacaggagg tgattcagtg ttaaaaacag aacgtaaaca actaatttta gaggagttaa
     1141 atcaacatca tgtagtttct ctagaaaaat tagttagttt gctagaaacg tcagaatcaa
     1201 cggttcgaag agacttggat gagttggaag cggaaaacaa gcttcgtcgt gtgcatggtg
     1261 gagcagaact cccccactcc ttacaggaag aagaaaccat tcaagaaaaa tctgtcaaaa
     1321 accttcaaga aaagaagttg ctggctcaga aagcagcctc tctcattaaa gaaaaagatg
     1381 tcatctttat cgatgctgga acaacaactg cttttttgat tcatgaattg gtcaataaga
     1441 atgttacagt tgtgaccaac tccattcacc atgccgctca gttggttgaa aagcagattc
     1501 cagctgtcat ggttggagga aacgtcaaga cggcgacaga tgctagtatc gggggcgttg
     1561 ctcttaacca gattaaccaa ttgcactttg accgtgcctt tatcggaatg aatggtgttg
     1621 acgatggcta ttatacgact cctgatatgg aggagggagc tgtgaaaaga gctattttgg
     1681 agaatgccaa gcagacctac gtcttggtgg attcgtcaaa aattggacaa acttgctttg
     1741 ccaaggtagc accactcaaa cgcgctatcg ttatcactag tcaagggcat gagctcttgc
     1801 aggttattaa ggagaaaacg gaggtaatag aagtatgatt tatacagtca cactcaatcc
     1861 atccattgac tatatcgttc gtttggacca agtcaaagtt ggtagtgtaa atcgtatgga
     1921 cagtgatgat aagtttgctg gtgggaaagg aatcaatgtc agccgtgtct tgaaacgttt
     1981 gaatatacca aatacagcga cgggatttat cggtggcttt actggtaaat ttatcacaga
     2041 tactttagca gaggaagaaa tcgagacacg ttttgtccag gtggcagaag atactcgtat
     2101 caatgttaaa atcaaagcag accaagaaac agaaatcaac ggaacgggtc caactgttga
     2161 atcggttcag ctagaagaat tgaaagctat tttatctagt ctgacagcag aagatacagt
     2221 tgtctttgca ggttcaagtg ctaaaaatct aggcaatgtt atctataagg atttgatttc
     2281 cttgacgcgc cagactggtg cgcaagtggt ctgtgacttt gaaggacaga ccttaattga
     2341 tagtttggac taccagcctc ttcttgtaaa accaaacaat catgaacttg gagcgatttt
     2401 tggggttaaa ctcgaaagtt tagatgaaat tgagaaatac gctcgtgagt tactggctaa
     2461 gggtgctcaa aatgttatta tctctatggc tggggacggt gctcttcttg tcacatctga
     2521 gggagcttac tttgctaaac caatcaaagg aacagtcaaa aattcagttg gggctggtga
     2581 ttctatggtt gctggattca caggtgaatt tgtcaaatca aaagacgcag tagaagcctt
     2641 caaatgggga gtggcttgcg gaacggcaac taccttctca gatgacttgg caacggcaga
     2701 acttattaaa gaaacatatg gaaaagttga ggtagaaaaa cgatgaaaat tcaagaccta
     2761 ttgagaaaag atgtcatgtt gctagatttg caggcaactg aaaaaacagc tgtcatcgac
     2821 gagatgatta aaaatttgac agaccacggt tatgtaacag attttgaaac atttaaagaa
     2881 ggaattttgg cgcgtgaagc tttgacttct actggtttgg gtgatggaat cgcaatgcct
     2941 cacagcaaaa acgctgctgt caaagaagcg acagttctat ttgctaagtc aaataagggt
     3001 gttgactacg agagcttgga tggacaagca actgacctct tcttcatgat tgcagctcca
     3061 gaaggtgcca atgatactca cttggcagcc ttggcagaat tgtctcaata cttgatgaaa
     3121 gacggttttg cagacaaact tcgtcaagca acatctgcag accaagttat cgaacttttt
     3181 gaccaagctt cagaaaaaac tgaggaactt gttcaagcac ctgctaatga ctctggtgac
     3241 tttatcgtag ctgttacagc ttgtacaaca ggtattgccc acacttacat ggcccaagaa
     3301 gcccttcaaa aagtagctgc tgaaatgggg gttggtatca aggtcgaaac caacggtgct
     3361 agcggtgttg gaaatcaact aactgcagaa gatatccgta aggctaaagc tattatcatt
     3421 gcagcagaca aggccgttga aatggatcga tttgatggaa aaccattgat caatcgtcca
     3481 gttgctgacg gtatccgtaa gacagaagag ctaattaact tggctctttc aggagatact
     3541 gaagtctacc gtgccgctaa tggtgcaaaa gctgcaacag cctctaacga aaaacaaagc
     3601 cttggtggtg ccttctacaa acacttgatg agtggtgtat ctcaaatgtt accattcgtt
     3661 atcggtggtg gtatcatgat tgcccttgcc ttcttgattg acggtgcttt gagtgttcca
     3721 aatgaaaacc ttggcaatct tggttcttac catgagttag cttctatgtt catgaaaatt
     3781 ggtggagctg cctttggttt gatgcttcca gtctttgcgg gttatgttgc ctactctatt
     3841 gctgaaaaac caggtttggt agcaggtttc gtggctggtg ctattgccaa agaaggtttt
     3901 gcctttggta aaattcctta tgtcgcaggt ggtgaagcaa cttcaactct tgcaggtgtc
     3961 tcatctggtt tcctaggtgc ccttgttggt ggatttatcg caggtgcctt ggttcttgcc
     4021 atcaagaaat acgttaaagt tcctcgttca ctcgaaggtg ctaaatcaat ccttctattg
     4081 ccacttcttg gaacaatctt gacaggattt gttatgctag ctgtgaatat cccaatggct
     4141 gcaatcaaca ctgctatgaa tgacttccta ggtggtcttg gaggaggttc agctgtcctt
     4201 cttggtatcg tccttggtgg aatgatggct gttgacatgg gtggaccagt taataaagca
     4261 gcttatgtct ttggtacagg tacgcttgca gcaactgttt cttcaggtgg ttctgtagcc
     4321 atggcagcag ttatggctgg aggaatggtg ccaccacttg caatctttgt cgcaactctt
     4381 cttttcaaag ataaatttac taaggaagaa cgtaactctg gtttgacaaa catcatcatg
     4441 ggcttgtcat ttatcactga gggagcgatt ccatttggtg ccgctgaccc agctcgtgcg
     4501 attccaagct tcatccttgg ttcagcagta gcaggtggac tcgttggtct tactggtatc
     4561 aaactcatgg cgccacacgg aggaatcttc gttatcgccc ttacttcaaa tgctctcctt
     4621 tacctcgttt ctgtcttggt aggagcaatc gtaagtggtg tggtttatgg ttacctacgc
     4681 aaaccacaag cataaaaaat agaaaaatga aaagattgga ccgtttggtg cagtcttttt
     4741 ctcttcccga aatgcctgtg aaatatggta taatagaaga atggcaaaca agaatacaag
     4801 tacaacaaga cggagaccgt ctaaagcaga actggaaaga aaagaagcga ttcaacgaat
     4861 gttgatttcg ttaggaattg cgattttatt gattttcgca gccttcaaat taggggctgc
     4921 aggtataacc ctttataatt taattcgctt gctagtgggt agcctagctt atctggcgat
     4981 attcggccta ttaatctatc tcttcttttt caagtggata cgaaaacagg aaggactctt
     5041 atctggcttt ttcaccatat ttgctggctt actcttgatt tttgaggcct acttggtttg
     5101 gaaatatggt ttggacaagt ccgttctaaa agggaccatg gctcaggttg tgacagatct
     5161 gactggtttt cgaacgacta gctttgctgg agggggcttg atcggggtcg ctctttatat
     5221 tccaacagcc tttctctttt caaatatcgg aacttacttt attggttcta tcttgatttt
     5281 agtgggttct ctcctagtca gcccttggtc tgtttacgat attgctgaat ttttcagtag
     5341 aggctttgcc aaatggtggg aagggcacga gcgtcgaaaa gaggaacgct ttgtcaaaca
     5401 agaagaaaaa gctcgccaaa aggctgagaa agaggctaga ttagaacaag aagagactga
     5461 aaaagcctta ctcgatttgc ctcctgttga tatggaaacg ggtgaaattc tgacagagga
     5521 agctgttcaa aatcttccac ctattccaga agaaaagtgg gtggaaccag aaatcatcct
     5581 gcctcaagct gaacttaaat tccctgaaca ggaagatgac tcagatgacg aagatgttca
     5641 ggtcgatttt tcagccaaag aagcccttga atacaaactt ccaagcttac aactctttgc
     5701 accagataaa ccaaaagatc agtctaaaga gaagaaaatt gtcagagaaa atatcaaaat
     5761 cttagaagca acctttgcta gctttggtat taaggtaaca gttgaacggg ccgaaattgg
     5821 gccatcagtg accaagtatg aagtcaagcc ggctgttggt gtaagggtca accgcatttc
     5881 caatctatca gatgacctcg ctctagcctt ggctgccaaa gatgtccgga ttgaagcacc
     5941 aatccctggg aaatccctaa tcggaattga agtgcccaac tccgatattg ccactgtatc
     6001 tttccgagaa ctatgggaac aatcgcaaac gaaagcagaa aatttcttgg aaattccttt
     6061 agggaaggct gttaatggaa ccgcaagagc ttttgacctt tctaaaatgc cccacttgct
     6121 agttgcaggt tcaacgggtt cagggaagtc agtagcagtt aacggcatta ttgctagcat
     6181 tctcatgaag gcgagaccag atcaagttaa atttatgatg gtcgatccca agatggttga
     6241 gttatctgtt tacaatgata ttccccacct cttgattcca gtcgtgacca atccacgcaa
     6301 agccagcaag gctctgcaaa aggttgtgga tgaaatggaa aaccgttatg aactctttgc
     6361 caaggtggga gttcggaata ttgcaggttt taatgccaag gtagaagagt tcaattccca
     6421 gtctgagtac aagcaaattc cgctaccatt cattgtcgtg attgtggatg agttggctga
     6481 cctcatgatg gtggccagca aggaagtgga agatgctatc atccgtcttg ggcagaaggc
     6541 gcgtgctgca ggtatccaca tgattcttgc aactcagcgt ccatctgttg atgtcatctc
     6601 tggtttgatt aaggccaatg ttccatctcg tgtagcattt gcggtttcat caggaacaga
     6661 ctcccgtacg attttggatg aaaatggagc agaaaaactt cttggtcgag gagacatgct
     6721 ctttaaaccg attgatgaaa atcatccagt tcgtctccaa ggctccttta tctcggatga
     6781 cgatgttgag cgcattgtga acttcatcaa ggctcaggca gatgcagact acgatgagag
     6841 ttttgatcca ggtgaggttt ctgaaaatga aggagaattt tcggatggag atgctggtgg
     6901 tgatccgctt tttgaagaag ctaagtcttt ggttatcgaa acacagaaag ccagtgcgtc
     6961 tatgattcag cgtcgtttat cagttggatt taaccgtgcg acccgtctca tggaagaact
     7021 ggagatagca ggtgtcatcg gtccagctga aggtaccaaa cctcgaaaag tgttacaaca
     7081 ataaaaaaat agcttctttc cgagtttgga gggaagctat tttagtggct attgattact
     7141 tttatactct tcgcaaatct cttcaaacca cgtcagcttc gccttgccgt actcaagtac
     7201 tgtctacggc tagcttccta gtttgctctt tgattttcat tgagtattat tttctgaagt
     7261 tggagtattg ggctgttttt cgttttcagt agcaggttta cttgaagcag gagtagaaga
     7321 gtcctgagtt gctgttttct gatcttcttt tttctcttcc ttgacgctag attttggtgt
     7381 ttcctcttgc tgtgtttttt cttgactagt gttagtctct ttagttggac tggtgttttc
     7441 cttaggggat tccttttgga tttctttgac aatggttgtc gtctggcttg tcgtaggttc
     7501 ttttttaata tttttgttat tatccaaggc gttcataatc gtgatacttg cggtaatcaa
     7561 gccaaggata ctagcgattg tagcaacggt tttttgaaag actgtaaagc cttttttgat
     7621 gtgttctgtt tttggttttg aagttctacg atagttagac atacattctc tcctttgatt
     7681 atgatttatt atactctgtt tctttaaaaa aatcttaaaa aaagagaaat tgccctttct
     7741 tgtcgcaagc tccgtttcat gatacaatag aggaagtgat tttagaaagc gtgagaaaca
     7801 tgatttactt tgataattca gcgacgacca agccttatcc tgaagccctt gaaacctata
     7861 tgcaggtcgc ttcaaaaatt ttaggaaacc catctagtct ccatagtttg ggagaccaag
     7921 caacacgaat cttagatgct tctcgccaac agattgcaga tttaatcggt aagaaaagcg
     7981 atgaaatctt ctttacctct ggtggaacag aaggggataa ctgggttatc aagggtgtgg
     8041 cctttgaaaa agctcagttt ggcaagcaca tcattgtttc agccattgaa catccagcag
     8101 tcaaagagtc agccctctgg ttgaaaagtc aaggatttga agtggatttt gctccagttg
     8161 ataagaaagg cttggtcgat gttgaggcgt tagcaggttt gatacggcct gatacaatcc
     8221 tcgtttctat catggctgtg aacaatgaaa tcggctctat ccaacctatt gaggctattt
     8281 cagaattctt ggcagacaag ccgactattt ccttccacgt tgatggggtt caggcgctta
     8341 ccaagattcc gactgaaaag tatctgacag aacgagtgga ttttgcgact ttctctagtc
     8401 acaagttcca cggggttcga ggtgttggct ttgtctatat caaatctggc aagaagatta
     8461 cacctcttct tacaggtggt ggccaggagc gagattatcg ttcgacaact gaaaatgtgg
     8521 cagggattgc agcgacagcc aaggccctcc gtttgtctat ggaaaagcta gatatcttta
     8581 ggagcaagac tgggcagatg aaggcagtga ttcgccaagc tcttctgaac tatccggata
     8641 tttttgtctt ttcagatgag gaagactttg cacctcatat tctgactttt ggaatcaaag
     8701 gtgttcgagg tgaagtcatc gttcacgcct ttgaagacta tgatattttc atctcaacaa
     8761 cctcagcttg ttcatctaag gcaggaaaac cagccggtac cttgattgcc atgggagtgg
     8821 acaaagataa ggccaagtca gctgtgcgtc ttagcctaga cttggaaaat gatatgagtc
     8881 aggtcgagca gtttttgacc aagttaaaat tgatttacaa tcaaactaga aaagtaagat
     8941 aggagcattc atgcagtatt cagaaattat gattcgctac ggagagttgt caaccaaggg
     9001 taaaaaccgt atgcgtttca tcaataaact tcgtaataat atttcggacg ttttgtctat
     9061 ctatacccaa gttaaggtaa cagcagatcg cgaccgtgcc cacgcttacc tcaatggagc
     9121 tgattacaca gcagttgcag aatctctcaa acaagttttt ggaattcaaa acttttctcc
     9181 tgtttataag gttgaaaaat ctgtagaagt tttgaagtct tctgtccaag agattatgcg
     9241 ggacatctac aaggaaggta tgacctttaa gatttctagc aagcgtagcg accacaactt
     9301 tgaacttgat agtcgtgaac tcaaccaaac acttggaggg gctgtattcg aagccattcc
     9361 aaatgtgcaa gttcaaatga aaagtcctga catcaatctt caggtggaga ttcgtgaaga
     9421 agcagcctat ctttcttatg aaaccattcg tggggctggt ggtttgccag ttggaacttc
     9481 aggtaaaggg atgctcatgt tgtcaggagg gattgactca cctgtagcag gttatcttgc
     9541 tcttaagcgt ggggtggata tcgaggcagt tcactttgct agtccaccat atactagtcc
     9601 tggtgccctc aagaaagcgc aggacttgac ccgtaaattg accaagtttg gcggaaatat
     9661 ccagtttata gaggtgcctt tcacagagat tcaagaggaa atcaaagcca aagcgccaga
     9721 agcttatttg atgactctaa ctcgtcgctt tatgatgcgg attactgacc gtattcgtga
     9781 ggtacgaaat ggtttggtta tcatcaatgg ggaaagtcta ggtcaagtag ccagccaaac
     9841 ccttgaaagt atgaaggcta tcaatgctgt taccaacact cccatcattc gtcctgtggt
     9901 taccatggac aagttggaaa tcattgacat cgcccaggaa atcgatacct ttgacatttc
     9961 aatccaaccg tttgaagact gttgtaccat ttttgcacca gatcgtccaa aaacaaatcc
    10021 taaaattaag aatgcggagc agtacgaagc gcgtatggat gttgaaggct tggttgagcg
    10081 agcagtggct ggaatcatga ttactgaaat cacacctcaa gccgaaaaag atgaagttga
    10141 tgacttgatt gataatctac tctaattcag aaaatccaaa agaatagcga aaatcagtaa
    10201 aaaaagttag ttttttctct aaaaacaggt aaaaaactaa ctttttttat ttttatgata
    10261 taatgatata aaattttgaa tatagagagt tttctgacaa tgaatcaatc ctacttttat
    10321 ctaaaaatga aagaacacaa actcaaggtt ccttatacag gtaaggagcg ccgtgtacgt
    10381 attcttcttc ctaaagatta tgagaaagat acagaccgtt cctatcctgt tgtatacttt
    10441 catgacgggc aaaatgtttt taatagcaaa gagtctttca ttggacattc atggaagatt
    10501 atcccagcta tcaaacgaaa tccggatatc agtcgcatga ttgtcgttgc tattgacaat
    10561 gatggtatgg ggcggatgaa tgagtatgcg gcttggaagt tccaagaatc tcctatccca
    10621 gggcagcagt ttggtggtaa gggtgtggag tatgctgagt ttgtcatgga ggtggtcaag
    10681 ccttttatcg atgagaccta tcgtacaaaa gcagactgcc agcatacggc tatgattggt
    10741 tcctcactag gaggcaatat tacccagttt atcggtttgg aataccaaga ccaaattggt
    10801 tgcttgggcg ttttttcatc tgcaaactgg ctccaccaag aagcctttaa ccgctatatc
    10861 gagtgccaga aactatcgcc tgaccagcgc atcttcatct atgtaggaac agaagaagca
    10921 gatgatacag acaagacctt gatggatggc aatatcaaac aagcctatat cgactcgtcg
    10981 ctttgctatt accatgattt gatagcaggg ggagtacatc tggataatct tgtgccatcc
    11041 atagtgaaat cccttggtca gaaaatctac cagattgtct gagatttttt gcagaaaaat
    11101 ggtaagttaa gaaaggaaaa aacgaaatgc atattgaaca tcttagccac tggagtggtc
    11161 atcctaaccg tgaaatgtac cttaaccgtt atggacatgg tgggattcca gttgtggtct
    11221 ttgcttcatc aggtggtagt cacaacgaat actatgattt tggcatgatt gatgcctgtg
    11281 cttcctttat cgaggaaggc cgtgtccagt tctttaccct atctagtgtg gatagtgaga
    11341 gctggttggc tacttggaaa aatgctcatg accaagcgga aatgcaccgt gcctacgaac
    11401 gttatgtgat tgaggaggcc attcttttat caagcacaag acaggttggt ttgatggcat
    11461 gatgacgaca ggttgctcta tgggagccta tcatgcactt aatttcttcc tccagcatcc
    11521 agatgtcttt accaaagtga ttgctctcag tggtgtttac gacgcacgtt tctttgtcgg
    11581 tgattactac aacgatgatg ctatttacca aaactcgcca gtagattata tttggaacca
    11641 aaacgacggc tggtttattg accgttaccg tcaggcagag attgtgctgt gtacggggct
    11701 tggagcctgg gaacaagatg gtttaccatc cttttacaag ctcaaagaag cctttgacca
    11761 gaaacaaatt ccagcctggt ttgctgaatg gggacatgat gtcgcccacg actgggaatg
    11821 gtggcgtaaa caaatgcctt atttcctcgg taatctctat ttataaaagg agttacctat
    11881 gaattacctt gttatttctc cctactatcc acaaaacttt caacagttta ccatcgaact
    11941 agctaataaa ggcatcacag tcttgggaat tggtcaagag tcttacgagc aattggatga
    12001 gcccttgcgc aatagcttga ccgagtattt tcgtgttgat aatcttgaga acatagatga
    12061 agtcaaacgt gcagttgctt ttctctttta taaacatggt ccaattgacc gcatcgagtc
    12121 tcacaatgaa tactggcttg agctagacgc aacactcaga gaacaattca atgtttttgg
    12181 tgccaaacca gaggatctca aaaagacgaa atataagtct gaaatgaaga aacttttcaa
    12241 aaaagcaggt gttcctgtgg tacctggagc tgttatcaag acggaagcag atgttgatca
    12301 agcagtgaaa gaaatcggtc ttccaatgat tgccaaacct gataatggag tgggagcagc
    12361 cgcaaccttt aaacttgaga cagaagacga tatcaatcac ttcaagcaag aatgggacca
    12421 ttcaaccctt tatttctttg aaaaatttgt cacttccagc gaaatctgta cctttgacgg
    12481 gctcgtggac aaggatggaa agattgtctt ctcaacaacc tttgactacg cctatacacc
    12541 gcttgacctc atgatttata agatggacaa ttcttattat gtgctcaagg atatggatcc
    12601 taaactgcgc aagtatgggg aagcaattgt caaagaattt ggtatgaaag aacggttttt
    12661 ccatattgag ttcttccgtg agggggacga ttatattacc atcgagtaca ataaccgccc
    12721 tgcaggtggt tttaccattg atgtttataa ctttgctcat tccttggacc tttatcgtgg
    12781 ctatgcagct attgtcgcag gagaggagtt cccggcgtca gactttgaaa ctcagtattg
    12841 tttggctact tctcgccgtg caaatgctca ctatgtttat tcagaagagg atttgcttgc
    12901 caaatatagc cagcagttca aggttaaaaa agtcatgcca gctgccttcg cggaacttca
    12961 aggagattac ctgtatatgc tgacaactcc gagtcgacaa gaaatggatc agatgattgc
    13021 tgatttcgga caacgtcaag aataagaact atcggattaa ggaaattcac tcccttaatc
    13081 cttttgtttt gtctggtaaa aaataagagc atcctaacaa ggtagctatc ataaaacttg
    13141 ttcgataact atttgaagca ggattaggtg gctagaaatt gaattttaac atttcaattg
    13201 agtcatagta ttgtgttttc gtatccttaa atcagctaaa aggatccatg acgacaccta
    13261 tacgatatag ttttcaggat accaaacaag tctattaata ctcaatgaaa atcaaagagc
    13321 aaactaggaa gctagccgca ggttgctcaa aacactgttt tgaggttgtg gatagaactg
    13381 acagagtcag tatcatatac ctacggcaag gtgaagctga cgtggtttga agagattttc
    13441 gaagagtata aaatattcag gtgacgcata gatatagtta attgaagctt tgtttgaaat
    13501 ctgataaaat aatgatatta ctaagttcta aaaactaaag aaaagggaag atatgattac
    13561 aggcgaatta aaaaataaaa tcgatcagct gtgggaaatt ctttggacag aaggaaacgc
    13621 aaatccttta acaaatattg aacagttgac ttatctctta tttatgaaag atttggatag
    13681 tgtcgagctt ggacgtgaaa gtgatgctga atttctaggg attccttatg agggagtttt
    13741 tccaaaagat aaacctgaat accgttggtc aacttttaaa aatataggag atgctcagga
    13801 agtttatcgt ttaatgactc aggagatttt tccgtttatt aaaaatctca agggggatac
    13861 agatgataca gccttttcac gatatatgcg agaagctatt tttcaaataa ataaacctgc
    13921 tacgcttcaa aaggcaattt ctatcttaga tgtttttcca actaggggat tagatgtaga
    13981 ttttgataat gacaaacaaa gtattactga tatcggagat atctatgaat atctgttatc
    14041 aaaattgtcg accgcaggta aaaatggaca gttccgtaca cctcgtcaca tcatcgatat
    14101 gatggttgag ttgatgcaac cgactatcaa agatatcatc tcagatcccg ctatgggttc
    14161 tgctggcttc ttagtatctg ctagccgtta cttaaagcgt aagaaagatg aatgggaaac
    14221 caatacagat aatatcaatc attttcataa tcagatgttt catggaaatg atacggatac
    14281 gactatgttg agacttgggg cgatgaacat gatgctacat ggagtagaaa atccacaaat
    14341 cagttacctt gactcgctgt ctcaagataa tgaagaagcc gataaatata ctttggtttt
    14401 agcaaatcct ccttttaagg gctcacttga ctacaattca acctctaatg accttcttgc
    14461 aaccgtaaaa accaaaaaaa cagaattact ctttctttct cttttcttgc gaactttaaa
    14521 accaggtgga cgagcagcag ttatcgtacc tgatggtgtc ctttttggtt cgtctaaagc
    14581 tcataaagga attcgtcagg aaattgtaga gaatcataag cttgatgctg taatctcaat
    14641 gcctagtggt gttttcaagc cttatgctgg agtttcaact gccattctca tctttacaaa
    14701 aactggtaat ggtggtactg acaaagtctg gttttacgat atgaaagcgg atggtttaag
    14761 tttggatgat aagcgacaac cgattagcga caatgatatt ccagatatta tcgaacgctt
    14821 tcatcatctt gaaaaagaag cagaacgtca gagaacggat caatctttct ttgttccagt
    14881 tgctgagata aaggaaaatg attatgattt gtctatcaat aaatataaag agattgagta
    14941 tgaaaaagtt gagtatgaac caacagaggt catcttaaag aaaatcaatg atttagaaaa
    15001 agaaattcaa gctggcttgg ctgaattaga aaaattactc aagtagggag gtggctgtat
    15061 gaaaaaagtg aagttggggg aagtcttatc tctaaaaaaa ggcaagaaag ccactgtact
    15121 tgctgaacaa acaactctaa gccaacgtta tattcaaata gatgatttaa gaaataataa
    15181 taatttaaaa ttcactgaaa gtttaaatat gactgaagca ctcccagatg atattctgat
    15241 agcatgggat ggagctaatg caggaacagt tggttatgga ttatcgggag ctgttggtag
    15301 tacaattacg gtcttaaaaa agaatgagcg atacaaagaa aaaattatat cagattactt
    15361 gggagtcttt ttggaaagta aatcgcagta tttacgagaa cattcaacag gtgcaacaat
    15421 tcctcattta aacaagaata tattacttga tttacaatta gaattgctag gtatcgaaga
    15481 acaagagaac attatctgta ttcttaatac gattaaaagg cttattacta aaagaaaatt
    15541 gcagttagat gaactaaact tgctcgtcaa atcccgattt aacgagatgt ttggggaaaa
    15601 taaaatattt gaaagcattg ataacttatt tgatattata gatggtgata ggggcaaaaa
    15661 ttatcctaaa tcagatgagt tgtttagtga ggagtactgt ttatttttaa atacaaagaa
    15721 tgttactaaa aacggatttt cattcgatac aaagcaattt atcactaaaa caaaggataa
    15781 attacttcga aaaggcaaac ttgagcgtta tgatatagtc ttgacaacaa gaggtactgt
    15841 tggaaatgta gcgtactacg atgaattaat aaaatataaa catttacgta taaattcagg
    15901 tatggtaata ttacgtccca agacaccaaa tctaaatcag aaatttatta tccatgtttt
    15961 aaggaataat aattatagtc gagtgatatc aggaagtgct cagcctcagt taccaattac
    16021 aaaattaaaa aaaatacttc tccccctccc cccactagcc ctccaaaatg agttcgcaga
    16081 ctttgtagtc caggtcgaca aatcacaatt tgcttgtgag atagctataa aagtgtggag
    16141 aaatagcttg aaatttagta taatatagct aaactattta tttaaagtga gaaaaaaatg
    16201 ggaaatttta gctttctttt aaaaaatgac gaatatgaat ctttttcaaa accttgcatt
    16261 gaagctgaga atatgattgc tacatcaact gtggctactg cctttatggc gcgtcgtgct
    16321 ttagagcagg ctgtccattg gatatatagt cacgattcat atttagaagc tccctatcgt
    16381 gctactctat cttctttagt atgggatgat gattttaggg atatcgtaga ttctgaactc
    16441 cacaagcaga tagttctgtt gattcggtgg ggaaaccatg ctgctcatgg tggtgaaatt
    16501 aaggaacgag aagcgatttt agctttgcat catttgtatc agtttgttaa ttttatcgat
    16561 tattgttaca gcaatgagtt tgtggagcgt tattttgatg agaagtgctt accactttca
    16621 gcaaacatca aataccgaga aactccacaa tctatgataa agttacaaga cagtttacca
    16681 gaactgcctg attttcatga acagatggct gctcagtccg tagaagttca agagacttat
    16741 actgaaaaac gtgagactgc agcgcaacgg caagatgtgc ctttccatat tgatcaatta
    16801 tctgaggcag agacaagaaa gctctttatt gatatcgatc tccgtttagc aggatggata
    16861 tttgaagaaa actgtcgtgt tgagatagcc gttgatggtc tcaagcacgg ttcaggaatt
    16921 ggttactgtg actatgtact ttatggtaaa aatgggaaaa ttttagcgat tgtggaggct
    16981 aaaaaagcct ctgtcaatcc agaagtaggg gaagtacagg tcaaagaata tgctgaagct
    17041 ttggagaaac atatcggcta tcagccaatt tgctttatta caaatgggtt gaagcactat
    17101 atacttgatg gtccgaaccg ccgccagatt gcaggctttt actctcaaga agaattgcaa
    17161 ttagtgatgg atagacgtca tcttcaaaaa ccgcttgagg atatttctag taaaattagg
    17221 gacgatattt ccgggcgtca ctaccaaaaa catgccattg caagcgtttg tgaagctttc
    17281 tctgatcatc gtagacaggc acttttggtt atggcaactg gggcggggaa aactcgtaca
    17341 gcagtttctc tagttgatat cttatcacgt cataactggg taaaaaacgt tctcttctta
    17401 gccgatagaa cttccttggt taagcaagcc tatgattcgt ttagaaaatt actcccagat
    17461 ctttccgttt gtaacttctt agaagataaa gaaggagctc aatcaagtcg tatggtcttt
    17521 tcaacttatc cgaccatgat tggagcgatt agtggtcaag aagaagtaaa tcaacgccct
    17581 tttactgttg ggcattttga ccttatcata attgacgaat ctcaccgttc tatttatcag
    17641 aaatacaagt ccatttttga ttattttgat gcaaggattg taggcttaac agctactccg
    17701 cgtcaagatt tagataaaaa cacctatgga ttctttaatt tggagaatgg ggttccaaca
    17761 tatgcatatg atttggaaga ggctgttaaa gacggatatt tagtagccta tcattctatc
    17821 gaaaccaaac tgaagctacc tacggatggt ctacattatg atgatttgtc cgaagaagaa
    17881 aaggaacatt ttgatagcaa atttgaagac gatagctgtg aaaaagatat tgatgggagt
    17941 gtgtttaatt cctttatttt caataaaagt acagtagaaa ttgttttaaa tgaactcatg
    18001 acaagaggaa ttcagacagc ctcgggtgat gaaattggta aaactattat ttttgctaaa
    18061 aatcatgacc atgcggaata tatcagaggt atttttaaca accgctatcc tgaaaaaggg
    18121 agcgactatg ctcaggtgat tgattatagt attaagcatt atcagacctt gattgatgat
    18181 tttaaaatta aggagaagta tcctcaaatt gcgatttctg tcgatatgtt agatacaggt
    18241 attgatgtac cagaggttgt taatttagtc ttcttcaaga aagtacgctc taaaactaag
    18301 ttttggcaga tgattggtcg aggaacccgt ctatgtaaag atttatttgg acctgagcag
    18361 gataagaaaa acttcttggt atttgattat ggggacaatt ttgattattt tcgtgcagat
    18421 ccaagagatg gagagggtcg tcacattgtt tcgctgactc agcgtttatt taatatcaaa
    18481 gtggacttga ttcgagaact tcagggactc caataccaag aagatcagtt tgcgagagca
    18541 taccgtcagc agcttgtctc ggaacttcaa ggtcgtatag agagcttaaa tgagttggac
    18601 ttcagggttc gtatggtttt agatacagtt tatagctata ggaaattgga aagttggcag
    18661 aatctaactg ctgttacaag tgaaaccatt caaaaaaatc tctctccgct tttatttgat
    18721 gaagataaag aagatgagat ggcgaggaga tttgatttgt ggttgcttca tattcagttg
    18781 gggcaactga cagctaaatc ttccactgtt catatttccc aagtgatgaa gacggctaga
    18841 gctctttctg ctattggcaa tatcccgcag gtttttgagc aggctgaaat tatcagggaa
    18901 gtacaggagc ctgaattttg gaaagaagtt aacttgtctg atttggaaaa aattcgtctt
    18961 gctattcgag atttattaca gtttttggat aaaacagacc gtaaacccta ctatgttaac
    19021 tttgaagatc gtatactctc cactgttcac gagaccacag catttttgca ggtcaacgat
    19081 cttcggtctt acaatgaaaa agttgacatc tgatgatatg cttgcacttg aaaaattgct
    19141 ttgggaaaaa ttaggtagta aagcagacta ccaaagtcat tatgaaaata aggcaattcc
    19201 gagattggtt cgtgagatta ttggcttaga tagagagtct gccaatcgta ttttttctaa
    19261 atttttgtcg gatgagaatc ttaatgccag gcagatttca tttgtaaaat tgattgtaga
    19321 ctacattgta gaaaatggtt ttttagagac gaaagtgtta acgcaagagc cgtttaaatc
    19381 ttatggttct gttcaactac tcttccaaca ccaactacca gtacttcgta atattgttca
    19441 aatcattgaa cttatcaata atcgagctgg agaagcggct taaattctaa agtgattgcc
    19501 atgctgagac tcatttaaaa ttaaaaagag tagaaattta tgctatatat gagaagtttt
    19561 attaggaaga atgtcatcgt ttttctagaa tacagtatca gttgttaagt ggctgataaa
    19621 tttcaaagta gatacttgta ccacgatgtt tgttgatcga gttattaaca aaagagctac
    19681 tttgatttta aagaaataga aaacaaaaag ccgagcaaga attcaattgc aggagaaaat
    19741 gaaataatac tcaatgaaaa tcaaagagca aactaggaaa ctagctgcag gctgctcaaa
    19801 acactgtttt gaggttgtag a
//
LOCUS       DBEJKC010000034        19174 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.034, whole genome shotgun sequence.
ACCESSION   DBEJKC010000034 DBEJKC010000000
VERSION     DBEJKC010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19174
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.034"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..498)
                     /locus_tag="ACL3G6_001320"
     CDS             complement(<1..498)
                     /locus_tag="ACL3G6_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HGR0545842.1"
                     /translation="MRTYENKEELKAEIEKTFEKYISEFDNIPENLKDKRVDEVDRTP
                     AENFAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRK"
     gene            complement(535..663)
                     /locus_tag="ACL3G6_001321"
                     /pseudo
     CDS             complement(535..663)
                     /locus_tag="ACL3G6_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CD1845 family protein"
     gene            complement(725..1594)
                     /gene="rsmI"
                     /locus_tag="ACL3G6_001322"
     CDS             complement(725..1594)
                     /gene="rsmI"
                     /locus_tag="ACL3G6_001322"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HGR0545843.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(1597..1914)
                     /gene="yabA"
                     /locus_tag="ACL3G6_001323"
     CDS             complement(1597..1914)
                     /gene="yabA"
                     /locus_tag="ACL3G6_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HGR0545844.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(1954..2844)
                     /locus_tag="ACL3G6_001324"
     CDS             complement(1954..2844)
                     /locus_tag="ACL3G6_001324"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HGR0545845.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLAHQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(2841..3479)
                     /gene="tmk"
                     /locus_tag="ACL3G6_001325"
     CDS             complement(2841..3479)
                     /gene="tmk"
                     /locus_tag="ACL3G6_001325"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HGR0545846.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(3699..4496)
                     /gene="proC"
                     /locus_tag="ACL3G6_001326"
     CDS             complement(3699..4496)
                     /gene="proC"
                     /locus_tag="ACL3G6_001326"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HGR0545847.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGIVMEAVHQAYKRTQELGK"
     gene            complement(4500..5762)
                     /locus_tag="ACL3G6_001327"
     CDS             complement(4500..5762)
                     /locus_tag="ACL3G6_001327"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HGR0545848.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASFLPRLEQ
                     VLVAERKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(5772..6881)
                     /gene="proB"
                     /locus_tag="ACL3G6_001328"
     CDS             complement(5772..6881)
                     /gene="proB"
                     /locus_tag="ACL3G6_001328"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HGR0545849.1"
                     /translation="MKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAMLHEAGHEL
                     ILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQIVSAQILL
                     TQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDEVKVGDNDTLSAQVAAMVQ
                     ADLLVLLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTGGMLTKIK
                     AATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLAFYAQSQG
                     SIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKGRVQFGAS
                     ALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(6982..8859)
                     /gene="cbpE"
                     /locus_tag="ACL3G6_001329"
                     /gene_synonym="pce"
     CDS             complement(6982..8859)
                     /gene="cbpE"
                     /locus_tag="ACL3G6_001329"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HGR0545850.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAETGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSLISVVKVNG
                     KKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQTS
                     DSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPSFQ
                     AGWHKSVYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFYLT
                     DSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYMGQWYY
                     FAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKANDW
                     YFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKSAT
                     IKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSESE
                     Q"
     gene            complement(8862..9749)
                     /locus_tag="ACL3G6_001330"
     CDS             complement(8862..9749)
                     /locus_tag="ACL3G6_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR0545851.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLSLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(9739..10200)
                     /gene="lspA"
                     /locus_tag="ACL3G6_001331"
     CDS             complement(9739..10200)
                     /gene="lspA"
                     /locus_tag="ACL3G6_001331"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HGR0545852.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(10197..11105)
                     /locus_tag="ACL3G6_001332"
     CDS             complement(10197..11105)
                     /locus_tag="ACL3G6_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGR0545853.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11098..11304
                     /locus_tag="ACL3G6_001333"
     CDS             11098..11304
                     /locus_tag="ACL3G6_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGR0545854.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLHYLPFSR
                     QSYFQNQFKKISGYTPLQYRKEKR"
     gene            complement(11356..12027)
                     /locus_tag="ACL3G6_001334"
     CDS             complement(11356..12027)
                     /locus_tag="ACL3G6_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0545855.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12081..12302)
                     /locus_tag="ACL3G6_001335"
     CDS             complement(12081..12302)
                     /locus_tag="ACL3G6_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HGR0545856.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            12573..13382
                     /locus_tag="ACL3G6_001336"
     CDS             12573..13382
                     /locus_tag="ACL3G6_001336"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0545857.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWKELSPADIEYLYDLAEKS
                     NVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(13563..14438)
                     /gene="aguB"
                     /locus_tag="ACL3G6_001337"
     CDS             complement(13563..14438)
                     /gene="aguB"
                     /locus_tag="ACL3G6_001337"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0050126 - N-carbamoylputrescine amidase
                     activity [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HGR0545858.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(14448..15533)
                     /gene="aguA"
                     /locus_tag="ACL3G6_001338"
     CDS             complement(14448..15533)
                     /gene="aguA"
                     /locus_tag="ACL3G6_001338"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047632 - agmatine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HGR0545859.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRSF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALEKPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(15530..16657)
                     /gene="nspC"
                     /locus_tag="ACL3G6_001339"
     CDS             complement(15530..16657)
                     /gene="nspC"
                     /locus_tag="ACL3G6_001339"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0045312 - nor-spermidine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HGR0545860.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(16657..17916)
                     /locus_tag="ACL3G6_001340"
     CDS             complement(16657..17916)
                     /locus_tag="ACL3G6_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HGR0545861.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(17913..18773)
                     /gene="speE"
                     /locus_tag="ACL3G6_001341"
     CDS             complement(17913..18773)
                     /gene="speE"
                     /locus_tag="ACL3G6_001341"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HGR0545862.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDREGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            19028..>19174
                     /locus_tag="ACL3G6_001342"
     CDS             19028..>19174
                     /locus_tag="ACL3G6_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0545863.1"
                     /translation="MLYVGIDIAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLN"
BASE COUNT         5536 a         4472 c         3461 g         5705 t
ORIGIN      
        1 ttttctgatt ttagttctga aagttccaaa aggtgcaacc gtatttacat gaataaactt
       61 atacacttcc caagtcgctg ttttagtcgc ttcatcagcc cactttctca tatgcggttc
      121 aaataattct tcctcactca acgaatcaat cattgcagag atagaattaa tattttcatt
      181 taattttgct ttcaactctt gcagagataa atgagcgtag gtatctgtga accactgata
      241 taattcacca agttgattcc atttaaattt atccgatggt gtttttactt gaagcccctt
      301 tctttcatct tcttcccatt taagaaccaa gttggtccag ccaacctgat aagcaaagtt
      361 ttctgctgga gttctatcaa cttcatcaac tctcttatct tttaaatttt ctggaatatt
      421 atcaaattct gaaatatatt tctcaaatgt tttctctatc tcagctttta gttcttcttt
      481 attttcgtat gttcgcaaaa aatcaccttc tttctgattt atcaatcctt tgatttaaaa
      541 tgaccttatt tttctattta taccttctag gaacgctata actgctgctc caaccatcgg
      601 tattccgtat gggcttaata aaaaacttaa taccaaagct tctataccaa gtgatacatc
      661 tttatattat catcactaat taagttaaac agaaacagac agaattatta catcctgtct
      721 ccctttattg tttttcttcc cagtcgtggt aggcagcgta gagctgactt ttattccact
      781 ggtaaatctt agcgacttcc ttgatagctt ggtttttctt cacaccttgc tggatgcggg
      841 tttgaatttc tacgaacaag tcttcctcgt ccttttcctc cacaccctga ctggcaccct
      901 caacaatgag aagacattcg cccttgagtg gcgtttcagc aatgctttct aataactcag
      961 agatagtacc tcgttggtat tcttcataga ttttggtcaa ttccctgacc aagacaactg
     1021 agcggtcacc gtagacttct aacatatttt ccaacgtgtc tgctacacga tgaggtgatt
     1081 cataaaaaat ctgtgtttca ggataatctt ttttcaagcc aaaaaattgc ttctgctgac
     1141 ctgattttct cggtaaaaaa ccgtaaaaga tatgtggctg tggcgctaaa ccactggcaa
     1201 tcaaggcaga aattcctgca gaggcacctg gaactgtcac aactgcaatt tcttcctcaa
     1261 tagctgcctt aactaaatca tgaccagggt ctgaaatgct aggcaaaccg gcatcagaga
     1321 cctgagcaat actttgccct gctttcaaga aaccaatcaa atcaggaatt ttttccttgg
     1381 cattgtgctc atgaaaactg atctgcttgg tggaaatgtc aaaatgcttg agcaaaagac
     1441 ctgtattgcg cgtatcctca gcagcaatcc aatctacttc tttcaaggtc tggatagctc
     1501 gaaaggtcat atcatctaga ttgccaatcg gcgttgccac tagatacagc ttgccatagg
     1561 gagactgccc cttaaaactt ttttgaatct gcatgcctac tccctgtata gcaactcgtc
     1621 acaaaacata cattcctcgt cctgctctcg acgttgtcca taaaaatcat tacatacgtg
     1681 aaatccatca cggtaaatgc gacggacact ttcacgaaca tgcttggcct tgacaggagc
     1741 atctgcttcc acctcaccca agcgttctcg caacttacta ttttccaagc gaagagctgt
     1801 attttcctct accaggctct tgagattttt cttgatggct tccacatcgg ctaaggttac
     1861 caataattgt tgggaaaaat catccagcgc gtcaaataat tcttttttgt ccataaaaca
     1921 gccctttcct ttctttatca ttcatttttg agtttatatt tctttcaaga ccagatattc
     1981 catggcattt tgaaagctga cattagcttg ccacattttt ctagcttcta gtaaatcttg
     2041 tagaatcact cttactctta cctgcaagag gtcctgccca cagagaactt caagaatccg
     2101 taaaacctga tcctgttttt ccttatcatc tgccaagttg gctaatttgg caacctgtag
     2161 ataactttct tttttcttag ctactaacca agtcagcagg cgttcacttt catcgaccaa
     2221 ggtccaaaaa cttgcctgat gtgccaactt ttctgcttca gctcgcgatt gactaaactt
     2281 agctaaaaga gtcgcttttt tcttaacaag tcccatttgt tctaagagta agataagttt
     2341 ttcttcttgc tttttaaagt ggaagatctg agtccgactt cggattgtcg gtaacatctt
     2401 ttcctcatcg ctagtcaaga agaaaatata aacttcactc tggggttctt cgatgacctt
     2461 gagcagagaa ttggctgcgt tgggatgcat tttatccgct tgctcgatga taaagacctg
     2521 ttgctggctt tcaatccctg cttgagaaaa ctgtcccacc aattcccgaa tgcgttctgt
     2581 cttgatgacc tgattgactg gcttaatcaa ggtgacatct ggaaactctt cctgttcaat
     2641 cagcttgcaa cttcggcatt tctcacatgg taagacgcca actttatccg tacaaaagag
     2701 gctcttagct aaaaattgcg ccatttccaa gcttccaaag aaacctgaaa agagataggc
     2761 gtgattgagc tggtcttgtt ctaagatacg gacaaaacgg tcaaactgag ctggttgcca
     2821 agcctttagt tgatcttgtt tcatttggcc aagcccattc cgtcaaacaa gacagccttg
     2881 gtagtttcca caacttgctc caaagggaga ctagcatcaa tcttgacaat gcgatttccc
     2941 tctttatcca gaagagaaag gtagccttga cgaacttttt tatgcaagtc caacccttcc
     3001 aaatccaaac gattaacctc gcggtcacta ttagcagcaa tacgagccag cccttcttcc
     3061 acctcgatgt caaaatagag tgtcaaatcg ggtttgaggc catctgtcgc aaactgattg
     3121 agccagtcaa tggcttcaat atctaagcca cgaccaaatc cctgataggc aacagaacta
     3181 tcgataaaac gatccatgat gaccaacttg ccagcttcaa gggctggaag aactttttcc
     3241 accaaatgct gtctgcgact ggcaatatag agaagtagct ctgttttagc atccatctga
     3301 gtatgacttg gatccaaaat cacttcccga atcttctccc caatcaagac tccgccaggt
     3361 tcacgggtcg tcaacacctc tactcctttt tcctctaaaa ttggtagcag agcctctaaa
     3421 acactggtct tgcctgctcc ctctggtccc tcaagagaga ctaaaaatcc ttttgacatg
     3481 tctaactcat ttctttttta ctacttctat tctatcaaaa aaataggggt ttgtgacaat
     3541 ctttttgtct tctcatttca tactcaatga aaatcaaaga gcaaactagg aagctagccg
     3601 caggctgtac ttgagtacgg caaggtgaag ctgacgcagt ttgaatttga ttttcgaaga
     3661 gtatcaacca ccataaaaga ggcagataaa actacctctt atttacctag ttcttgtgtt
     3721 cgtttatagg cttgatgaac tgcctccatg actatgcctc gaaaagcatg cgcttctagg
     3781 cttgctacgc cagcaatagt cgaaccgcct ggactacaaa cttgatcttt caaaactcca
     3841 ggatgttgct ggctttctag gaccaattgc ccagctccta ccacagtttg ggctgccatt
     3901 ttcaaggctg tttctcgtgg taatcccgtc tgaacacctg catctgccaa agcctcaata
     3961 aagagataga caaaggctgg tccacagcct gcaagacctg tcgctgcatt gattaagctt
     4021 tctcctaatt caaccaagag accagccttg gataaaagct gacaaaagag ctcactgtcc
     4081 tcagccctgc aattaggaga caaggcataa ctaatcactc cttgcccgat agaagcaggg
     4141 gtattaggca tcatacgaat aattcggtgt tgacttggga taagacttgc tagtttttct
     4201 aaggtcaatc cagctgccat cgaaatcaaa agaagacttt ctcttttttc aaggatggtc
     4261 tggtattgag aaagcagttc agaaaactga gcaggcttaa ctcctagaaa aatcacatct
     4321 gcttctgcaa acatttcttc attgctggaa gcctgaccac caaagtctgc aatgaaagca
     4381 tctaccttag cttgactacg attggcaagg agaatctcat ctgacgtcct agtctgcaag
     4441 acagattttg ccaagctagc acccatattc cccaaaccga taaatccaat cttcatctct
     4501 tactccctta tctgcccatc accagtgacc acatacttgt agctagtcaa ttccttcaag
     4561 cccataggac cacgcgcgtg caatttctga gtagaaatcc ccatttcaca accaagacca
     4621 aattgtcctc catctgtgaa acgagttgag gcattaacat acaccgctgc agagtccact
     4681 tgatctgtaa agtatgctgc agcttcagca ttttccgtca caatggcatc cgaatgatgg
     4741 gtactgtggg attcaatatg cgcaaccgct tcttctaaac tgctcacaac cttaacagct
     4801 agaatatagt ctaaaaactc ggtatcaaag tcttgtgctt gagcagcttg acctgaaaca
     4861 aactggcttg ctttgctatc taggcggaat tgaattggtt ccagtccagc ttccttacgc
     4921 tctgcaacca acacttgctc caagcgagga aggaagcttg ctgccttgtt ttcatgaacc
     4981 agcagaacct ccatggcatt acaaacagaa ggacgactgg ttttagcatt gttgatgata
     5041 gacagcgcct tgtcttcgtc tgcatcctta tccacataga catggacaat cccagtccct
     5101 gtctcgataa caggtacaat cgcattctca accactgcat tgatcaagcc agctcctcca
     5161 cgaggaatga gaaggtctag atagcccttg gccttcatca tagcataact actttcacgg
     5221 ctagtatcct ccaccagttg aatcacattt ggatgaatag tagtcgtctc caagcccttc
     5281 ttcaaggctg tgacaatggc atgggttgtt tgataggcat ccttaccact acgaagaaca
     5341 accgcatttc cactcttaag agtcaaagca gccgcatcag acgtcacatt tggacggctt
     5401 tcatagataa taccgatgac acccatagct acacgttttt ttgtgataac caaaccattt
     5461 tcaagctgac ttgtttctaa aacttcaccg attggatctg gtaaggcaac cacttcacga
     5521 attcctcttg ccatcgcttc tatacgatct gcatccaaat aaagacgatc caacatcaca
     5581 tctgagattt tccccttagc cgctgccata tcgagggcat tagccgctaa aatttcctca
     5641 gtagcagcca ctaagtgatc agccatggct agcaaggctt ggtttttcac ttcttcacta
     5701 gctgtgttaa tcgatttttt aacagcctgt acctgttcaa attgttcttg tctactcacc
     5761 atagtttacc tctaaaattc tgtaaaaagt agttggattt caggagtaat ggaaatccag
     5821 tcgtcacggt aaatcaagac acccttggct ttttgagaac gcaacatatc ctccaaagca
     5881 gatgctccaa attgcacgcg tccttttcca agtgattttc cactttcctt gtcaaatact
     5941 gtcacgatat caccgtaaga aaagactcct tctgcttcaa cgataccaga taagagaaga
     6001 ctctttccat gttgagagag agcttccgca gcccctttat caacccaaat agaaccttga
     6061 ctctgagcat agaaggcaag ccattgtttc tgggtacgaa gccccttctc ttgagcaaca
     6121 aagtaagaac catcctcggt ctcctctgcc gcctcaatca tggaatctga tttcaaggat
     6181 gagcagatat aaacaggaac tcctgattcc gtcgcgatag ttgcagcctt gattttggtt
     6241 aacatacccc cagttccgtt tgacgaacca gctccaccag ccatatcaat aatctcacga
     6301 ttgatggtct cgattctctc caagcgtttg gctcttggat ctgaattagg atttccagta
     6361 tagagaccgt ccacatctgt caagagaacc aaaaggtctg cttggaccat cgccgctact
     6421 tgggcactta gagtgtcatt gtccccaacc ttgacctcat caataacgac actatcattc
     6481 tcattgatga taggaattgc cccacggttg agtaaaaccg acaaagcctg atgggcattt
     6541 ttataacgac gcttatccac aaagtcatct tgggtcagca agatttgtgc agaaacgatt
     6601 tgacgcaaga gaagattggt cgtatattct tccaacaaaa gtccctgccc taccgctgct
     6661 gaagcctgtt tatcagcaat cttagtcgga cgctttttaa atcctaaggc tccaaaacca
     6721 gccgcaatgg cacctgaaga caccaaaatc aactcatgac cagcctcgtg cagcatagcc
     6781 aactgctggg taatatcctt taccttacta cgtgataaac ttccatcctc atttgtcaga
     6841 gaagaagtac ccaccttaaa gacaatccgt ttgtatttca tagtctcact ccgattattc
     6901 atatttatcc attataacat gaataacagg aaatagaaaa gagttgatag gaaaaagaag
     6961 gccctaaaac cttcttttct actactgttc tgattccgat ttgtttacac tcgtttcaga
     7021 gctttgtgaa gttgaggatg tcaaatcttg actagttgaa gaatttgtaa cactttcatg
     7081 ttgactcgtt tctttatttt caagatcctt tttcactact tctttggatt cttttatttc
     7141 tgaatgactt gtagttttaa ttgtagcaga tttctcgatc gaaacatcca ctaaccaggc
     7201 accacttgaa tccacagtat agccttctgg tgtcttacca ttcacaagta attgaccatt
     7261 ttctttcaag aagtaccatt tatccttgtc cttgatccaa cccacagctc gtgaaccgtc
     7321 tgtcttgtag aaataccaat catttgcctt tttatgccag ccttgcttca tagctcctga
     7381 atcttccaga taataatgtt gaccagcaac ttctatctca cctgtcttca tgacaccagt
     7441 agaatccata tagtaccagg tttctttatc ttttacccag cccattttca tttcccctga
     7501 tggagcaaag taataccatt gccccatata ttgaagccat cctgtcttca tagaaccatc
     7561 aacatccaaa taataccact gctctttatc ttgaacccaa ccaatttcca tctgattttc
     7621 tttgttaaaa taataccaga ttccatcaat tttcttccaa tttttagcag aagcaccaga
     7681 gtctgtcaaa tagaaccaat gattgttcca ttttttccat tgattctgta acaagatacc
     7741 cgtttggtta aagtaatacc attcaccttc gatttcattc caaccgacag catactctcc
     7801 tgtagaatca ggcgcttgat accaccagtt cccatataca ctcttatgcc aaccagcttg
     7861 aaaacttgga atcggcttgt aggatgttga aatattgaca aaaccgtctt ttcgaatatc
     7921 aaaaactgtc gcatcatagt ctttgctggc tgcgttgatt ctctcaattc ctcgttcttt
     7981 gagccaatta acatactcac tatcaacacc atttttccaa ggtagactat ccgaagtttg
     8041 aacaatcaaa ctcggactca aatttttaat gaaatccttg gtatttgatt tgttggtatc
     8101 atggtgatga ttaaacttca tcaaatcaac ttttccaatg agaggaccat acttgtcttc
     8161 tgctccatga acattatcta aatcgccccc aaggtaaatt ttcttgccat tgactttcac
     8221 cacgctaatc aaggaattgt catcccaaat tttctttaat tcacccgatg aatcagtttc
     8281 attttcataa ttatagagct gaatatccat gtccccaaac tgaaaatgag catccccttg
     8341 tgtgatattt tgaataactg aaacacctgt ttctgcagca gtctgtaaaa ccttatcata
     8401 gccatacaga ttatcccata gacgttcaga attagtaata cgactatcac tatatttctt
     8461 aagatagact cggtcaactg gataggtaga cagtaattca tcaacatttc caatatgatc
     8521 actgtgggta tgggtcacca aaataaaatc aagtttttgg acacccaatt ccttcaaacg
     8581 acgaaagaca cggtctgtta gaacatgctt ataagacgtt tcaattcctt ctctccatgg
     8641 atagcgagaa tcacttccat ctgggaaatc ataatcttct cctgtatcca ccatggcaaa
     8701 atgtccattg ctttcaagaa taatcgcatc actgccacct tcttgaacat tgataaagtg
     8761 gattttattt cctgaacttt cttgagcctg aacattccca taccatgaca aacctaaaaa
     8821 agcgcctaca agtgctaaac tagttaattt ctttttcatt cttactttct caatctctcc
     8881 aaggtttcct taaaaatctc tgggatatct gctttaaatt ccaaggtctt acctgttctc
     8941 ggatgagtaa aacctaaagt cttggcatga agaaattgtc catgtccttt caaagtcttg
     9001 cgaggaccat agacctcatc accagcgact ggatggccga tataagccat gtggacacgg
     9061 atttgatgag tgcgccctgt ctccagttgc aactctacta agctataatc gccaaagcgt
     9121 tccaagacgt gaaaacgcgt cactgcaggc ttccctttag cagttacagc ctgtttctta
     9181 cggtcttttt cactccggcc aatcggcgct tcaattacac cacgatcatt aggcagattt
     9241 ccatgaacaa tcgcccaata tttgcggaga gactttttat ccttgagttc ttgggcaagt
     9301 gctagatgcg catcatcgtt tttagcaatc atgagaagac ctgacgtatc cttatcaata
     9361 cggtgaacaa tccctggacg cagaacccca ttgatacccg acaagtcctt aatatgatac
     9421 atgagggcat ttactagggt tccactggta tgaccagcac tcgggtgcac aaccattccc
     9481 tgaggtttgt taacgacagc cacatcctca tcttggtaga ctatttctag cgaaagatcc
     9541 tcagccacat actctaatac ctctggttct ggcacatggt aagtgacgac atcaccctct
     9601 tggactgtgt atttagcttt cttgacttga ccattgacca agacctggcc tgatttaatt
     9661 tgttcattcg cgagactacg tgataattct gacaaatctg acaaagcctt atccaaacgc
     9721 agaccaccag tttcaatttt aatttccatt tatttcctct tttagcattg caatcaataa
     9781 aataatcact ccaaccgtca gatagctatc tgccacattg aaaattgcaa agttgataaa
     9841 gtcaaggtgg aacatatcca caacaaagcc ctgactgacc ctgtcaataa agtttccaag
     9901 accacccgcg attattagag tcaaacccaa gaccatccag aatgagtcct ccatgtgttt
     9961 atgtaaatac caaatggcac ctatcacgac aaccagagta atgacagcga ataacagctg
    10021 ctgatcttgt aagatagaaa aggctgcacc tcgattttgc aggtaggtca agctaacgaa
    10081 attgggaatc caggagcgca cttcacccag tggaatctgc tggacgatat aggatttgac
    10141 caactgatcc agcccaatta aaagcagtac aatgactgcc actattgctc tttttttcat
    10201 gatttcctct tttgatcaaa atattcttgc atgacttcta cgaagagagt cccagcttga
    10261 ctaagctcca cttcttcacg tttaacatag accatgcggt tatctaggtt atccttgaga
    10321 cgaataactg taatgccatt aacactgtca ctatctaaaa atccagaacc tgtcgcatag
    10381 gcgtccgtcc gctccaaaat accattcaag gtggcacggt ctgtcacatt aaacatctgt
    10441 gagctagcgc tggtatcgac aaagttctct gaataataaa ggtactcgtc tttctcttga
    10501 gtgaaacgaa ccgttggtaa atccgctaaa tcctccatga ctaattcctc tttctgggct
    10561 aaaggatgac cctcacagag ataaatatgg gtatggaaag gaatcaattc gatgacctcc
    10621 agacctaact tttcaacccg ttgcataatc ccctttttat tttgattgtt gaggtagata
    10681 atcccaatct cactatgccc ttgcgccact tcatctaata tttgaacagt agttgattca
    10741 aaaatacgga agttcttata gtcaggatag cgctctgaaa aggccgtaat agttggtggt
    10801 aagaagtcat agtgctggct agcaacggaa aattcatctt tttcttcttc aggattggca
    10861 tactgatttt gaaaaatatc aaatccttta accaattctt gcgctttttc ataaaattcc
    10921 atcccacgac gggtcaagaa agtccctgag ctggtccgac ggaaaatctt aaagcccaac
    10981 tctttttcca aatcacgaac agaaatagac agactcggct gactaacata catcttttca
    11041 gcagcttcac gaaaagtacc actattggca atagccacaa catagcgtaa ttgttgaatg
    11101 ttcatcttct acccccaact tctttatctt ttcattatac catattttag aagttttcca
    11161 aaaaggaaaa aagaacatcc tattcttctt aactatcttc actatcttca ctatctgcct
    11221 ttctcacgcc aatcttattt tcaaaatcaa ttcaaaaaaa taagtggcta cacaccactt
    11281 cagtatcgga aagaaaaacg ttgactattt gtgaaaaaag aaaatgccgg aaaattccga
    11341 cattttttta gtaagctaac ttcctgaaaa taggagtaac caaacatccc agaaggcagt
    11401 gatattgatg agaatatgaa ctagtattgg atagtagaga tttttagtca tgcgatacaa
    11461 tagagctaaa atcagacctc cactagcata aatgaaaaaa gcaagaggag ttaaagcaaa
    11521 attgatatga atataaccga aaataatagc agaaagcaaa acatctccgt accaaggtga
    11581 gtttttgaaa aaggttgtca taagcacacc tcgataaatc aattcctcag caataggggc
    11641 gatgaagcaa acgatgagca agaaataagg gaactcctgt ctccccatca tttctaccgt
    11701 ttcattcaaa gaaatctgat ttgaagacag ggatatgaaa tacgaaaaga ggaagtcaga
    11761 catatatgaa atgatgtagc ccagtaaaag gtagatgaag tacctcagct gccacttgaa
    11821 atgaaaaatt ttctttcctg caaaaaccag tagatagatg accgctaaga aaagaactcc
    11881 gctctccatc aaaagcagaa tctgaaaaaa ttcacgactt gctggtagat agggctttgc
    11941 gaggtgattg aaaactctcc aaaaccaagt tgatttgtaa aaaattaagg acaatgctag
    12001 taaaatttga atagcccgtt ttttcatatt aaatcctctg ttttctcccc ttgtttcttc
    12061 atattcctaa taaattttac ttaaaatctc gcagcacttc ctttgcaaag atgattgcct
    12121 cctccaatat atcctaaatc ataggtgcct ctgggacaaa atccatgaac cggcagagtt
    12181 aatactggtt ctatttccca atcgtaccta ccattaggat ttttaccata gggatctgct
    12241 ccaccttgta tcagctctaa ttcttcattt gttagattta tattttttgt cattaaaatc
    12301 atgatatatt tcctccatta ttcttcagat tagttgagta atctactact catacctact
    12361 tacaaaaaaa ctattttaag ctagtttttt tatgcttgtc tagttgcaat attgacaagt
    12421 ttagtatatc atatctttgc caaatatcct cttcaaatct tgaattgtca tcgaaacgtc
    12481 ctaaactgca aaatcaatta gtctcaagct ttctatcaat ttcttctcca aaatatgcta
    12541 taataatagc aaaagataaa gaaggaagac ctatgattaa actactagcc ttggatatgg
    12601 acggcaccct cctcaatgaa gccaaggaaa tcccacaagc tcacattact gctattcaca
    12661 aagccattga aaaaggtgtc aaactggttc tctgtacggg tcgccccctt ttcggtgtcc
    12721 tcccctacta caaaaaactg gggcttgacc tccagaacga atatgttatt gttaacaacg
    12781 gttgttcaac tcaccaaacc agtgattggg gtctagttga ctggaaagaa ctgagtccag
    12841 ctgacatcga atacctctat gaccttgctg aaaagagtaa tgttcagttg acactttttg
    12901 acgagtcaca ttattttgtt ctcggtggca agcccaatca agttattgaa aatgatgcta
    12961 aactagtatt ttcagacctg actgaaattt ctcttgagga agcgactagt ggaaagttcc
    13021 ggatgttcca aggtatgttt ttaggaacaa aagaacaaac agacgatttt gagcagcgtt
    13081 ttgctgaaga gctttgccaa cgattcagtg gagttcgttc gcagcctgtc atttatgaag
    13141 caatgccact tggaacgaca aaggctactg ctctttcacg actagctgag attttgaaga
    13201 ttgattcctc agagattatg gccatgggcg atgctaataa cgatatcgaa atgctccagt
    13261 ttgcagggct tgggattgca atgggaaatg ccagcgatta tgtcaaatct cttgcggatg
    13321 ccgttacctc aagcaacgaa gaagacggcg ttgcgcgtgc tattgagaaa tatattctat
    13381 aaaaaagaaa agcaaataga cagaagttac tgctatttgc ttttttgcta atattttaaa
    13441 atacggacta atcaatagac aagaatagcg aatcataaaa atcgatttac tagatgccat
    13501 agtatcttat agttgctaat aagaagttag tctagcagaa tgaatctctc atttctccca
    13561 cactaatctg taatttgtct atacatttct ggtcttctat ctcgaaacaa gccccagttt
    13621 aggcgttcac tcgctccctt gtctaggtca taagtagcta acagaacagc ttcttcttgt
    13681 ctttcagctc gttctagaat agctcctgtt tcatccgtca taaaggagga accgtagaag
    13741 tcaagactgg aactctgtcc gccattttcc tcactaggag taacctcctc taaaccataa
    13801 cgattggctg cgatgactgg aacaatattc gctgctgcgt gcccttgcat agtacgttgc
    13861 cagtgaccac aactatctgt atccaaaatc ggctctgaac cgatggctgt tggataaaag
    13921 agcaattctg ccccattcag agcaagacag cgggctgttt cggggaacca ttgatcccaa
    13981 cagataccga taccaatctt agcatagcga gtattccaga ccttgaaacc agtgttacca
    14041 ggcgtgaaat agaatttttc ttgataataa tggtcatctg gtatgtgggt ctttcgataa
    14101 acgcccagca cttccccatc tgcatcaata acggcaatag agttatacaa gacattacca
    14161 tctttttcat agaaactgat tggtaaaaca acttgtagtt ccttagcaat caccttaaaa
    14221 tgctgaatgg cagtattttc cgctacagat tgggcatact ggtagtagtc atactgacgt
    14281 tcctgacaga aatagggatg ttcaaacaac tcgggcaaga gaataatttg ggctccttgc
    14341 tcagcagcct gacgtactaa acgctctgcg gtttggatat ttgttgccac atccttagcg
    14401 cattgcatct gaatggttgc aactcttaca tttctcatct ttttctccta ttctggaatt
    14461 tgttgggtga tacagtggat attgccacca cctaagagaa tatctctggc tggtattccg
    14521 acaactttac ggtctgggaa acacttgctg aggatatcta aggccacttg gtcgtttaca
    14581 tcctcaaact gtggaaccaa gacagccttg ttggcgatat aaaagtttac gtaggaagct
    14641 gctagtcgtt cacctgcgta tcgcttttct tctccttctt catagatgta gcctggcaaa
    14701 tcttcttctg tcacaacttg tcgaactgca gggataggca atttatgaat ggtgaagtga
    14761 caaccttttg catctgtttc ctgttctaag agttcgagat ctgcttttga catggcatac
    14821 tggggatcat tttcgtcatc tgtccaagct aaaacaacct cagcaggacc aacaaaggca
    14881 gcaacattat cgacgtgttc attggtttca tcctgataaa taccataagg aagccaaata
    14941 actttttcag caccaagact ttctaataat gtgttttcaa tctcctcttt agtcaggtta
    15001 ggattgcgac caggactaag caagcaactt tcagttacga gaatagttcc ttgaccatcg
    15061 ctatggattg cgcctccttc cagtacaaaa ggtttagcat catagacagg cttttccaag
    15121 gcctcagcaa aacgactggc tacttggtca tcctcttcat aatcttgata aagaccatca
    15181 taggtgcctc cccaagcatt gaaggcccaa tccacggcta atttcttacc tttatcattg
    15241 acgagaatgg ttgggccagt atcacgcgcc caggcatcat tggtgggaat gtctaaataa
    15301 acaaccttgt ctccaagata ggattgggct tcagatagat aggcctgctc caccaaaaga
    15361 tagactcttt ccccttctgc tatggtctcg atgatctgag taaatgatct tttagcagcc
    15421 tttccttgaa aaggccatga tcctggtcga gtcggccata tcatgagggt accatgatgg
    15481 ggttcgtact ctgctggcat gtgatagcct aatttttttg gactgtccat catgataatc
    15541 tccctttaaa gtcttgatag ccaaaagctt tgagtaagct acagtctccc tgttcgtcca
    15601 tgagatagag acttggcaat ccaataccat taaaggtatt atttttgaca aaagaataaa
    15661 tggccatgtc ttgaaaataa agtctgtctc cgatttggac tggattttca aaactataat
    15721 caccaatcac atcgcccgtc agacaggtat tagaagaaag tctgtaggta tgggcttttt
    15781 cctgtgcctc aaagccattt ctcaaaggtg gacgataggg catctcaagt acatcaggca
    15841 tatggcaggt cgcagaggcg tctaaaacca agatttccat accattttct acaatatcta
    15901 atacctcagt tgctaaataa cccgcattaa gcgcaatggc ttcaccaggc tcgatataga
    15961 tttcaagatt gtaagttttt cggatacgct tgatttctga aatcagcaaa tccacatcgt
    16021 aaccttctct tgtaatatga tgaccaccac ccatattgag ccattttacc tcatgtaagt
    16081 agggaccaaa ctgttcttct actgctttca aagttgtttg taaatcatct gctccctgct
    16141 cgcaaagggt atgaaaatga agtccgtcaa ccaaatctag caaatcactc ggaatcttgt
    16201 ctatagtaac tccaaagcga gaaccaggtg cacaagggtc atagagcgcg tgatctcctt
    16261 gagttgaaca ctgagggttg aggcgcaaac caacactgac accagcctct cgacaacgag
    16321 ccccatgctt acgcaactgt ctctctgagt taaagacgat atggtctgtt atcccaagca
    16381 attcctccat gtcctcatcc ttgaaagctg gtgcaaaaac atggacttca ccaggaaatt
    16441 cttcccttgc caatttggcc tcatagagtc cactagctgt cgtacctgat agatactggc
    16501 taatcaaggg ataagttttg tagagggaat atgccttctg ggcaagcaag accttgcaac
    16561 cggcctcttc ttgtacatat tgtagaatgc ggcaattagc ttctaacttg gccaagtcaa
    16621 taacataggc tggtgttggt acttgttcta acttcattag tccaccattt gtggattttc
    16681 aaccacaacc catggcaaac catactcatt caaagcttcc atgaatggat ctggatctaa
    16741 ctcctcaagg ttatacactc cagcttgttt ccaagttccg ttcatgacta attttgtccc
    16801 aatcatggct ggaactcctg tcgtataaga aatagcttgc gaaccaacct ctgcgtaaca
    16861 ttcctgatgg tcgcagacat tgtagatata gatagtcttt ttgacaccgt ctttgacacc
    16921 tgtaaagata catccaatat tggttttacc tacagtacgt ggaccaaggc tagcaggatc
    16981 tggaagcaag gctttcaaaa attgaattgg aacaatttct tggccgttaa agttaatggt
    17041 atccgtacga aggagtccaa cattttcaag acatttcatg tgcgtcaagt aagattgacc
    17101 aaaagtcata aagaaacgaa tgcgtttgac tccaggaatg ttcttggcca gcgattcgat
    17161 ttcttcatgg tgaaggagat acatatcttt ttgtccaact tgagggaaat catactcacg
    17221 cttgatagac atagcttcga cttcgaccca tttcccatct tcccagtaag aacctggcgc
    17281 agaaacctca cggagattaa tttctggatt aaagttggtt gcaaatggat aaccgtggtc
    17341 accgccatta cagtctaaaa tgtcgatata atggatttca tcaaaatagt gtttgagggc
    17401 ataagctgaa aagacactag ttacacctgg gtcaaaacca gaaccaagaa gagcagtcaa
    17461 gcctgcttct ttgaatttct cttgataagc ccactgccat gagtagtcaa agtaggctgt
    17521 aaaaccaagt tccttacaac gtttttcgta gatagcacgc cactcagggt cttctgtgtc
    17581 ttctgcttcg tagttggctg tatcgatata gtgaacacct gttgccaaac aagcatccat
    17641 aatggttaaa tcttgataag gcagagctac attcaaaaca gcttctggtt tgtagctttc
    17701 aatcagggca atcacttctt caaccttgtc agcatcaagt gctgcagttt caattttagt
    17761 acttgttttg ccttctagct tcgctttcaa gtcatcgcat tttgacttgg tacggctagc
    17821 aatcataatc tctgtaaatg tttcgctatc ttgacaaatc tttgaaatag caacttgggc
    17881 aacgccccca caaccaataa ctagtaaacg actcattttt ttccttcctc ttcttctaaa
    17941 atgtcctcaa catacttggg caacataaag gatcccacgt gtaagtttgc agtgtagtat
    18001 tctgtgaaaa gctggcgttt tttccaacct tccctgtcaa aatctttgac agggtggtat
    18061 tttttcgatg caaatccaaa caaccaatag ccagctgggc tagttggaat atgggcctga
    18121 taaacccgac tgattggaaa ggcttgattg accttgcggt gcatgcttcg gcaggccgac
    18181 tcatcctcgt caaagaaggg actcccatgc tggtaaatca tgatgccgtc ttccttcaga
    18241 gctcgataac tattgccgta gaattctttg gtaaagagtc cttccgtatg gccaaatgga
    18301 tctgtcgcat cgttgatgat aatatcgtaa tcatcttcgc agtttcgcaa aaagcgtagc
    18361 ccattttggt agtaaatggt aacacgagga tcatctagcc ctgcagcaaa gtctgggaaa
    18421 tactcacgac agacctcgac caacatttca tccggttcca cgatatcgat ttgttccagt
    18481 tcaggataga gtgttaatac ttgggcaaca ccgccgtcac cacccccaat aaccaatact
    18541 ttctttggat ttgggtggac agccatggga acgtggacgg tcatttcatt gtagacgaaa
    18601 tcatccgcat ctgagaacaa gacatggcca tttaaaatca gtattttccc aaaagctggc
    18661 gtatccaaga cttcgatatc ctgccattca ctttttccag cgtaaagttg cttggctgtt
    18721 ctcagagaca atttgacatc tggagtatga acttcagaaa accataaatc catctatttc
    18781 tccttatatt atatttagcg cagttagcta ctgccaaagc ccaagtggta tacttggaat
    18841 aagccactgt ggattagttc atttcctcca atcgcttgac gatttccgaa aggctctaac
    18901 cacagctttt gtttcaattg gtaatgagtt tgataacgca tagacgtttt atctcgtcta
    18961 aggtaacaag gcaaaaagtt cgtggataac caagtagact tgaaatacta tatctggagg
    19021 tactcccatg ctttatgtgg gcattgatat cgctaaaaat aaacacgatg ttacagcctt
    19081 gaatgttcca ggaaaaactg ttcttaaacc actcactttt tcaaataata aagctggttt
    19141 tgaactctta gatctgtctc ttcgacagct caac
//
LOCUS       DBEJKC010000035        18935 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.035, whole genome shotgun sequence.
ACCESSION   DBEJKC010000035 DBEJKC010000000
VERSION     DBEJKC010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18935
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.035"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            171..509
                     /locus_tag="ACL3G6_001343"
     CDS             171..509
                     /locus_tag="ACL3G6_001343"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HGR0545864.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVKEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQETLDKHYQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            699..2135
                     /locus_tag="ACL3G6_001344"
     CDS             699..2135
                     /locus_tag="ACL3G6_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGR0545865.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            2187..2426
                     /locus_tag="ACL3G6_001345"
     CDS             2187..2426
                     /locus_tag="ACL3G6_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET transporter"
                     /protein_id="HGR0545866.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            2556..2870
                     /locus_tag="ACL3G6_001346"
     CDS             2556..2870
                     /locus_tag="ACL3G6_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HGR0545867.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            2988..4967
                     /locus_tag="ACL3G6_001347"
     CDS             2988..4967
                     /locus_tag="ACL3G6_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR0545868.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFAQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNSFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSYVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            4977..5291
                     /locus_tag="ACL3G6_001348"
     CDS             4977..5291
                     /locus_tag="ACL3G6_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HGR0545869.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            5322..5828
                     /locus_tag="ACL3G6_001349"
     CDS             5322..5828
                     /locus_tag="ACL3G6_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545870.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFISPSPIIIFPIMLIVFSILATIEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFENLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            5908..7254
                     /gene="celB"
                     /locus_tag="ACL3G6_001350"
     CDS             5908..7254
                     /gene="celB"
                     /locus_tag="ACL3G6_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HGR0545871.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNSLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            7634..7810
                     /locus_tag="ACL3G6_001351"
     CDS             7634..7810
                     /locus_tag="ACL3G6_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545872.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALSLGMT"
     gene            8212..10425
                     /locus_tag="ACL3G6_001352"
     CDS             8212..10425
                     /locus_tag="ACL3G6_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="HGR0545873.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEDEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(10647..11123)
                     /locus_tag="ACL3G6_001353"
     CDS             complement(10647..11123)
                     /locus_tag="ACL3G6_001353"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HGR0545874.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDHKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTNPKQIEEAIQTLL"
     gene            11346..14549
                     /locus_tag="ACL3G6_001354"
     CDS             11346..14549
                     /locus_tag="ACL3G6_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HGR0545875.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSTWVDQKNSSADASTRVIEAKDG
                     AITISSHEKLRAALHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDIASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKSGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            14929..15305
                     /gene="tnpA"
                     /locus_tag="ACL3G6_001355"
                     /pseudo
     CDS             14929..15305
                     /gene="tnpA"
                     /locus_tag="ACL3G6_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002458050.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            15487..15549
                     /locus_tag="ACL3G6_001356"
                     /pseudo
     CDS             15487..15549
                     /locus_tag="ACL3G6_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596946.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(15693..16322)
                     /locus_tag="ACL3G6_001357"
     CDS             complement(15693..16322)
                     /locus_tag="ACL3G6_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HGR0545876.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSALSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(16332..17333)
                     /locus_tag="ACL3G6_001358"
     CDS             complement(16332..17333)
                     /locus_tag="ACL3G6_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HGR0545877.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(17364..18005)
                     /locus_tag="ACL3G6_001359"
     CDS             complement(17364..18005)
                     /locus_tag="ACL3G6_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HGR0545878.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(18024..18839)
                     /locus_tag="ACL3G6_001360"
     CDS             complement(18024..18839)
                     /locus_tag="ACL3G6_001360"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HGR0545879.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
BASE COUNT         6129 a         2965 c         3926 g         5915 t
ORIGIN      
        1 tcttgtttca attgactata aatcgctata agaaaaaatc attttattgg tataaagaag
       61 tgattgaaag taatggcgaa acgttagata attagttcat aaaaaacaag tttagatcct
      121 catctaaact tgttttttta aaattgaagg atgattttgg aggatataag atgacattga
      181 ctattcatgt atattataaa ggtgatggag atagtgcaat aaagtttgca agagaaatgc
      241 ttgatagtgg ccttgttaaa gaaattagaa atcaaaaagg taacttgaaa tacgaatatt
      301 ttttaccaat tgaaaaagag ggaactattc tccttattga tcagtggata aatcaagaaa
      361 ctttagataa acattatcaa tcaaagacaa tgcagaaaat cttagattta agaaaaaaat
      421 atcacttgca gatgcaagtt gaacgttata tagaagatga ttctgggatg ccagaaagcg
      481 ataagtcgtt tatagacaca gggaattaga attattgtga gagtttttgt agtttgaaag
      541 tattgaaaat cgtaaagata tcattacgag aatacaagaa gatattgttc tatttccatt
      601 aaaaattact tctttcctta acaataagga aaaagaatgc gttttcatct tttggtttaa
      661 ggtttataat aagagtatca aagtcaggag gaaaaaagat gactactttt aaagatggat
      721 ttttatgggg tggtgctgtt gctgctcatc aacttgaagg tggatggcaa gaaggtggca
      781 agggaattag tgttgctgat gttatgactg ctggtcgtca tggagtagct cgtgaaatta
      841 ctttgggagt tttagagggt aaatattatc caaatcatga ggcgatagat ttttatcatc
      901 gttataaaga agacatagca ctttttgctg aaatgggatt caagtgcttc cgtacctcta
      961 ttgcatggac acgtatcttt ccaaaaggtg atgagttaga gccgaatgaa gaaggattac
     1021 agttttatga taatcttttt gatgaatgct taaagaatgg tattgaacct gtcatcactc
     1081 tatctcattt tgaaatgcct tatcacttag tgaccgaata tggtggttgg aaaaatagga
     1141 aattgattga tttctttgct cgttttgcag aagtcgtatt taaacgttac aaagataagg
     1201 ttaaatattg gatgactttc aatgaaatca ataatcaagc gaattatcag gaagattttg
     1261 caccatttac taactcaggt attgtatatg aggaaggtga taatagagaa gcaattatgt
     1321 atcaagcagc acattacgaa ttagttgctt ctgcacgagc tgtaaaaatt ggtcatgaga
     1381 ttaatccaga ttttcaaata ggttgtatga ttgcgatgtg tccaatttat ccagttactt
     1441 gcaatcctaa ggatatctta atggcaatga aagctatgca gaagcgttat tattttgctg
     1501 atgtgcatgt tttaggtaaa tatcctgagc atattttcaa gtattgggaa cgaaaaggta
     1561 tttcagttga ttttactgac caggataaag aagatttact tggtgggact gtagattaca
     1621 ttggtttcag ttactatatg tcctttgcta tagactctca tcgtgaaaat aatccttatt
     1681 ttgattatct tgaaacagaa gatttagtga aaaataatta tgttaaggct tctgaatggg
     1741 agtggcaaat tgatccagaa ggtttacgtt atgcgttaaa ttggtttaca gaccactatc
     1801 acttaccact ctttattgtt gaaaatggtt ttggagctat agatcaagtt gcagcagatg
     1861 gtatggtaca tgatgattat agaattgaat atctaggtgc ccatattcgt gaaatgaaaa
     1921 aggctgtagt tgaagatggt gttgatttaa tgggttatac tccatgggga tgtattgatt
     1981 tggtttcagc tggtaccggt gaaatgcgga aacgttatgg ttttatttat gtagataaag
     2041 atgataatgg gaagggaagt tataatcgtt ccccgaaaaa atcttttggc tggtataagg
     2101 aagttatttc atctaacggt gaatcagtag aatagtataa acaaactgag attattctca
     2161 gtttgtttag catattgagg tgacatatga ttggaagtat tgcagcaatt ttaacaacat
     2221 ttgcattttt accacaagtt tttcgtgtag ttaagacaaa ggacacagga tctattgctc
     2281 taggtatgta tgttatgcaa gttattggta ttgcattgtg gcttgctcat ggtattcgta
     2341 taggagactt gcctttgatt ttagcaaata gtgtttcatt tctactctca ggaataattt
     2401 tattttataa attgaagtat aaataatttt tttccatatc atttaggaaa atgagggaat
     2461 tgtcattgga aacgctttat tttataataa aaatagataa caaataagcc aacttagcac
     2521 agctttgatt ggatttaaga aaaggagaaa atattatggc aaaagcttta attatttgtg
     2581 cagcaggaat gtcttcatca cttatggcac agaaaacaac agagtttcta aaaggaaaag
     2641 ggaaagatat tgtagttgat gctattagtg ctactgaagg agggaaagct atcgcagcag
     2701 cagcttttga tttgtatctt gtcagccctc aaacaaaaat gtactttaag caatttgaag
     2761 aggctggttc taaagcagga aaaccagttg tacaaatacc tcctcaagcc tatattccta
     2821 ttccaatggg aattgaaaaa atggctaatt tgattcttga gaatatttga tgaacacatg
     2881 aaatgtcaat aaatatttaa gttaagataa attgttttga gtttgatata aattgattta
     2941 agtgtataat atgcttcaat atatgaaaac atacgtttta ggagggaatg aatgtgttaa
     3001 acattaaaga gaaagatatc cttcaatttt taataaaaaa taaggaacgt tttgttacaa
     3061 gcaaagaact ggcagaatat ttatcctgtt cagatagaac tgtccgtaat gtactgaaat
     3121 taattgagaa gacaatgatt attcaaggag tccggttgat ttcaaaacaa ggtcaagggt
     3181 atcaaatatt ttttgagaat caaggcgctt accaggagtt tagacaaact tatgaactgg
     3241 aagaagacta tacgaaaact gcggtttcaa aaggtgatga tcgtttagta tttatcttaa
     3301 ataaattatt atttgagcaa gttccagttc tttttgatga tttagctgat gaactttacg
     3361 ttagtcgttc aacattatct catgatttca gaaagatacg agtgatgtta tcagagtata
     3421 atttgtccat tgagagtagg gcgaataaag gagtttatgt ctcaggcgag gaacgtgata
     3481 aacgacgttt tatcataaat tatttcctag agaatcaatt ttttaaaaca atacattgct
     3541 atgtaaaatt taactttttt gctcaaactg ttccattaga agaatttgct agaattgttt
     3601 tggatgaatg ccaagaggcc aacctaaaac tatctgattt tgtactacag aatttagtag
     3661 ttcacatagc attgtctgtg attcgtttaa aatccggatt tgaaataaaa aatatagact
     3721 gtcagatgac tgatgatgca atagagagaa aggttgctca aagaattctt tctaaagtaa
     3781 gagaagtaac aaatcaggaa tttccagttc aggaaataga ctacattact ttgcatttgt
     3841 tagctaagag tcaacaatgt caaaaaaatc agaagaatat ttctgaagaa gttttaaaaa
     3901 aatctttatt taaaacattt cagaatttag gattagatga tatgtataac ttttcttcag
     3961 atttccaact aattgaagga ttgataactc atctaatgac actacaagta cgtttagaaa
     4021 gccggattac cttaaataac cctttggtag atgaaattaa acagaattat agtgatatat
     4081 tctttatgac tagagaaatt cttgcaaata tggacaagtt cttggagtgg acaatatcag
     4141 atgatgaagt agcatatgta agtcttcact ttttagctgc tatggaacgt agcaaagaga
     4201 gtactaagtt taatattctt gctatttgtg caacaggatt tggtgcagcc caaatgttaa
     4261 gaaatcgttt ggaaacggag tttgggaagc gagtagaagt tgttgatgta ataggctatt
     4321 atgaattgaa tcaagaaaaa cttaaaggaa tagattttat agtgtcagct gttgatttat
     4381 caaatctata ttttcaaatt ccagttttta aagttagtgt gtttcttaag agtgatgaga
     4441 tggaaatgat tagaaaagct atggatcaga tgcaagtttc tagttatgta caatcatcaa
     4501 agattaataa atttgaaaac aacagcttta gacagtattt tagtaaagaa aattttttaa
     4561 tatgtactga atcagacaag gtaaatttac ttgaaaagat ggttgagagt ttatctgttg
     4621 gtgaatcaaa tgagtttgaa caatctttac tttatggaat taaacagcgc gaagaattaa
     4681 gttcagttgt tttttctgaa aaaattgcag ttccgcatcc tattcagccc tttggtacag
     4741 agggaaaggt ttcggttgca atttgtaaag attcgttact ctgggataat caaagttcat
     4801 atgtccagct agtatttctt ctatctccat caatatatgg gaacgaaggt ttggcaactg
     4861 tgactaaaaa gatagtctct ctgacagaga atgatgaatt gcaaaatcag ctaatatctt
     4921 gcaataactt tgaagatttt attaacatat ttgagaagat aaaataggag gttcatatga
     4981 atcaagagga actgcaggtt gcagcatttg aaattattct gcattcggga aatgcaaggt
     5041 cagaaataca tgaagcattt gcaaaaatga gagaaggtag ttttgatgat gcagaaagta
     5101 aattaaatca atcaaatgag ataattcttg aagcgcatca tgcacaaacc aaactcttgc
     5161 aagaatacgc aagtggagtg gaaattaaaa ttgaaattat catggtacat gctcaagacc
     5221 atttaatgac cactatgaca ttattagaag tagcaaagga aatgttagct ctttataaga
     5281 aagttaacta aatatgtgtt gttatataag gaggaaatga tatggataaa aaagaacgac
     5341 aaaaaattga acaacaacgt cgagagatgg ctctaactaa tacttttttt aatcgatatc
     5401 ttcttctacg ttattcaata gcactcttct tttttgggaa tatttattgg cttttgaatc
     5461 agtttattag tccctcgcct attattattt tccccattat gctcatagta ttttctattt
     5521 tagcaactat tgaacaattt aaactttatg gaaataggaa agaaaagttg ggaataacac
     5581 taatgtttgt tagaatacaa atgcttattt caataggatt acttgtttta acttggacaa
     5641 gttggtttga gaatcttttt ccgatttttg aaaataacca agtagcacgt ttatttgttt
     5701 ttgtagttct tctattaggt ttagttctga gtttgttaga cattagaaga attaaaaaaa
     5761 tttataaacg aacagataag gcttatcaac aatttgtcca attggaaaag aactcactta
     5821 gtttataatc ctgaactagt ataatttgta tttgaaacta gtctttaaaa agtaaaaatt
     5881 attatgtttt attaaggagg tctatttatg gatcaacaaa acgggttgtt tggttttctt
     5941 gaaaaccatg ttatgggacc aatgggcaaa cttgctcagt ttaaagtagt gcgtgctatc
     6001 acggctgcag gtatggctgc tgtaccattt actattgtag gatcaatgtt tttggtattc
     6061 agtattttgc cacaagcttt ctcattttgg ccaattgtgg cagatatttt ctctgcttca
     6121 tttgataaat tcacatcact ttacatggtt gcaaactatg cgactatggg ttctctatct
     6181 ctttatttcg ttctatcact tgcatatgaa ttgacaaaaa tttatgcaga ggaggaagaa
     6241 ctcaatatga attctcttaa tggtgccttg ctcgccttga tggcttttgt catgacagta
     6301 ccgcaaatca tttttgatgg tggaatgatg aagactgtga caagtctaaa agaaggtgca
     6361 gtaattgcag atggatgggc aatgggaaat ggagtcgcac gttttggtac aacaggaatt
     6421 tttaccgcaa tcattatggc aattgtgact gttcttattt atcgtatgtg tgttaaacat
     6481 aattgggtta ttaaaatgcc tgaagctgtt ccagaaggag tttctcgtgg atttaccgct
     6541 ttggttccgg gatttgttgt tgcatttgtt gttatcttta tcaacggtct tcttgtagca
     6601 atgggaacag atatttttaa agtcattgca attccatttg gttttgtatc caatctgact
     6661 aattcgtgga ttggtttaat gattatttat ctattgactc aactactttg gattgtaggt
     6721 atccacggtg cgaacattgt ttttgcattt gttagtccaa ttgctcttgc taacatggct
     6781 gaaaatgctg ctggcgggca cttcgctgtt gcaggtgaat tttctaatat gtttgtaatt
     6841 gcaggtggtt ctggtgcaac tttaggacta tgtttatata ttgcttttgc ctctaaatct
     6901 gaacagctta aagcaatagg acgagcatct gtagttccag ccttatttaa tattaatgaa
     6961 ccattaattt ttggattacc tattatctat aatccagcct tggctatacc atttatttta
     7021 gcaccaatgg ttactgctac tatttattac gtagcgaatt ctctaaactt tattaagcca
     7081 attatcgcac aggttccatg gccaactcca gtagggattg gagctttctt agggacagca
     7141 gatcttcgag ctgtattagt tgctctagta tgtgcatttg cagcattcct agtctatctt
     7201 ccattcatcc gtgtatatga tcaaaaattg gtgaaagaag agcaaggtat ctaataagta
     7261 aaaaagtata ctcgatgata gaatccatat agtttaaata atgagcgtta acattagcag
     7321 tgaagaggtc tttttaagat attcttctct gctttttcat attttttcgc tatgtagagt
     7381 atgaagcaaa atagaaagta gttcgaatag ttgataaaca gggaattgct gttatttaaa
     7441 aaaaacaata aagtaaagta tgttatcgta gaatacgata caatagtaaa aaagcaaaaa
     7501 gaatgcgttt tatatttggg tttgaggctt ataaaatagg ataagcgtac tgaaaactta
     7561 gatatgacaa acaaaataaa atttttaaaa gctacagaga aacatggtat aatgtatcta
     7621 aaggaggtag catatgtcct tagatataga taaagaaaag atgacaatca tgggaatagc
     7681 ttttgaaaac cgatccgttt ttaagagtgt ttggtatgct ttaagtacaa atatgattga
     7741 aggatggcga cctacggtta gtgatgttga aaaattacga gatgaagctc tttctctggg
     7801 gatgacttaa tgaagcgcaa ctgttatgag tcttatgact atgttgatcc ggataattta
     7861 tataccgatc cgggttcttc agttctaaga aataagcagg aaggaaaaaa gcacgcgagc
     7921 ttgaatatcg tatgattgct agtaagagtt tgaaattatt tatcaatcct atcttagtta
     7981 atagtttaaa agtagtttgt ttcacaactg cataagctta gaaaagttga aaagtgataa
     8041 ctctttaata aactcttggt ttgttaaaag atattttgtc cactacattt ttttcaattg
     8101 actattattt gtcatagata taacagatag aacattgcat tcagaataat gaaaaacgca
     8161 tcaaaaatgg tgcgttctgt ttttatgcta ccataaaagg aggaaaacaa attgaaaatt
     8221 tttaagggag agttttatcg aatctctgta ttaacagaca agctagtaag gttagaatac
     8281 tctcgaactg gaaattttga ggatagaacg acacaactta tctataatag agattttggc
     8341 caagtttcgt tagattatat cgagacatca aatgtactag atattatgac ggactatttt
     8401 catctgcact ttaataaagg agaatttaac gccgaaaatt tatttataga attaaaagga
     8461 aattttgccg tatatggtag tcgctggtat tttggtgaat ctattgaaac gttaaaagga
     8521 acagctcgga ctctggataa ggcagatgga gcaatctcgt tagaagatgg aattattagc
     8581 cgaaatggta tagccttatt ggatgattct caaggattta tttgggatga acaatctggt
     8641 tatattgaga gagaaaatca aattgacctg tatttctttg cctatgggca tgattataga
     8701 ggagcaatca gagactttta ccatttgact ggttcaacac ccttgttgcc aagatatgct
     8761 ttaggcaatt ggtggagtag atattggcct tatacgtcgg atgaatactt ggatttaata
     8821 gacagatttg aaacagagaa aattccatta tctatcggtg tgttagatat ggattggcat
     8881 ataactgaca ttccagctcg ttttggaagt ggctggacag gatatagttg gaatagaaac
     8941 ttaataccaa atccagaaca gttattgcaa caacttcatg atagaaagtt aaaactctcc
     9001 ttaaatgtcc atcctgctga tgggatacgg gcttatgaag aagcttatcc tcaaatcgca
     9061 aaacggttgg ggttaaatgt agaactagaa gaacctgcta tttttgattt ttttaatccc
     9121 tcttttaggg aagcctactt taaagatgtt cattatgagc tagaaaagca gggagtagat
     9181 ttttggtgga ttgactggca acaagggaca caaggtatgc tagatccact ttggctttta
     9241 aaccattatc actatcagga tagttgtaaa aatgcagaag gtggtttgat tttatcaaga
     9301 tatgcaggtc ctggtagtca ccgctaccct gttggttttt caggggacac tattattagt
     9361 tggaattcct taagatttca accctatttt acagcgacag catctaatat cggttatagt
     9421 tggtggagtc atgatatcgg tggacatatg ttgggggatt atgacgaaga gctacaaact
     9481 agatggctac agtttggtgt ttttagtccg attactcgat tacatagttc tagaagtcct
     9541 tttaatagta aagaaccttg gttcttttca gaaacaacat ctaagattat gaagaaatac
     9601 cttcgtttga gacatcagat gattccctat ctatatacca tgaatgtaaa gacacatgag
     9661 gaaggtgccc cattaatcag tccaatctat tatttctatc cagagaatga tgagagctat
     9721 aatgttccaa accaatactt ttttggaaca gaactgatgg tggctcccat tgtagaaaag
     9781 atggatttga cattccaatc tgcaaaagta gatgtatggt tccctgaaga tgaatggtat
     9841 gacttctttt cagagaaaaa atacacaggt ggtgtgaagt taagtgttta tagggacatc
     9901 tcgactacgc ctgtgtttgc aaaaagtggt gcaatcattc ccttggttgg ttctgagata
     9961 ggtatgggtg ttgatttacc tgaggttgta gattggtatg tattcccagg gaaacaacat
    10021 tcttttgaaa tgcttgaaga tcaaaatggt caaagatata aaacaagatt atcaatcgat
    10081 tgggaaatgg gaatggtaga gttagcatta caaggagatt ctagtatcgt tccaagcaat
    10141 agaaaacata gaattcattt taaaggaacg aatgtgtcta taattgaatt gccaaataag
    10201 aatgatacag ctaaatttga atggaaagat aataaaagga catctttaaa tgacgaagtt
    10261 tttagactac taaagacagc ttctcttcca tatgaattaa aagatagatt gttaaatcaa
    10321 ttcatcaatg cgaaaaactc tcatgactta atgaatatct tgcatcatca ggataaggaa
    10381 ttgagagggc gtttgttgga aatgatattt actagccaaa actaattgaa ataattagaa
    10441 agtcatttgt ttagtgtata tgaagattct gtatggtatt cgttatcact ggtcacattg
    10501 aaaatgtgaa ataagcacct acaacataga ctttacaaca cttcatgttt tatatcatgg
    10561 ggtgtttttc tatttaagtc aaagcccatc aaaaaatctc actattcatc aggttaaagg
    10621 aaacctaatc atagtgagat tgtgaattat agtagagttt gtatcgcctc ttcaatttgt
    10681 tttgggtttg tttttgaaga aaagcgttca aagacttgcc catcacgacc aatgagaaac
    10741 ttagcgaaat tccattcgat tcgttttcct agtgggccag atttatggtc ttttaaccag
    10801 acatagagag ggtctgcttc cttaccgttg accttaatct tggcaaaacg tgggaaggtg
    10861 gtttgaaaat gtaggctaca gaaggcgttg atttcctctg cgctgccggg tgcttgtccc
    10921 ataaactgat tgcaagggaa atccaatatt tcaaagccct gatcttgata gcgttcatag
    10981 agttcttgaa gtccctggta ctggggcgtt aaaccacatc cagtagcagt gttgacaatc
    11041 aagagaactt taccacgata gctatccaag ggagttgctt ggttgttttg gttcaaaacg
    11101 gaaaaatcat aaagtgaagt catgagggcc tcttttcttt ttctacattg taacagtttt
    11161 tacttttttc gtcgagtcgg atggaagata ttgttgaaga ataagccttc aatatgatag
    11221 aaaccgttta caaataactt taaaaatggt atgatttaat taaaccggtt tactttgttg
    11281 ctataaatct ctaatttgag atttagttcc tattgatttt acaatatgtt tattggagtg
    11341 tatacatgca aacaaaaaca aagaagctca ttgtgagttt gtcttcactt gttttatcag
    11401 gatttttatt aaaccattat atgacagttg gagcggaaga aacgactacg aataccattc
    11461 agcaaagcca gaaggaagtt cagtatcagc aaagggatac aaaaaattta gttgaaaatg
    11521 gtgattttgg tcagacggag gacggaagca gtccgtggac aggaagcaaa gctcaggggt
    11581 ggtcaacttg ggtagaccag aagaatagtt ctgcagatgc ctcaactcga gtcattgagg
    11641 ctaaggatgg ggctatcact atctcaagcc atgagaaatt aagggcagcg cttcaccgta
    11701 tggttcctat tgaagctaag aaaaagtata aactgcgttt caagattaaa acagatcata
    11761 aagtcgggat tgccaaagtt cgtatcattg aggaaagtgg taaggacaag cgattgtgga
    11821 attctgcaac gacgtcagga acaaaggact ggcagaccat tgaagcagac tatagcccga
    11881 ctttagatgt tgataaaatc aagctggagt tattctatga aacaggaact gggactgttt
    11941 cctttaagga tattgagctg gtagaggtag cagaccagcc ttctgaggat tctcaaacag
    12001 ataaacagct tgaggaaaag attgatttac caattggaaa aaaacatgtt ttttctcttg
    12061 cggactatac ttataaggta gaaaatcctg acattgcttc agtcaaaaat ggaattttag
    12121 aacctcttaa ggaagggaca accaatgtca ttgtcagtaa agatggcaag gaagtgaaaa
    12181 agattccttt gaagattcta gcctctgtta aggatgcata cacagaccgt ttggatgact
    12241 ggaatggcat catcgctggg aatcaatact atgattctaa aaatgaacag atggccaaat
    12301 taaaccagga attggaagga aaggtagctg atagcctatc tagtatttca agtcaggcgg
    12361 accgcaccta tttgtgggaa aaattttcaa attataaaat gtctgcaaat ctgactgcca
    12421 cttatcggaa attggaggag atggccaagc aagtgaccaa tccttcttct cgttattatc
    12481 aagatgaaac tgtcgttcga acagtcaggg attccatgga atggatgcat aaacatgtct
    12541 acaatagtga aaagagcatt gttgggaact ggtgggatta tgaaatcggt acacctcgtg
    12601 ccatcaacaa taccttgtct ctgatgaaag aatacttctc tgatgaggaa attaaaaaat
    12661 atacagatgt gattgaaaaa tttgtaccag atcccgaaca tttccgaaag acgactgata
    12721 acccattcaa ggctctaggt ggaaacttag ttgatatggg aagggtaaaa gtaatagctg
    12781 gtttactgcg taaggatgat caagaaattt cttctaccat tcgctcgatt gagcaagtgt
    12841 tcaagttggt agaccaaggt gaaggttttt atcaagatgg atcctatatc gaccacacca
    12901 atgttgccta tacgggtgct tatgggaatg ttttgattga tggcctgtct caactgttgc
    12961 cagtcattca aaagaccaag aatccaatcg ataaagataa aatgcaaacc atgtaccact
    13021 ggattgataa atcgtttgct cctttgctgg tgaatggaga gctgatggat atgagtcgtg
    13081 gacgctcgat cagtcgtgca aatagcgagg ggcacgtggc cgcagtagaa gtactaagag
    13141 ggattcaccg aatagcggat atgtctgaag gagaaaccaa acaacgtttg cagagtcttg
    13201 tgaagaccat tgttcaatcg gatagttatt atgatgtctt taagaatttg aagacttata
    13261 aggatatcag tttgatgcaa tccttgttaa gtgatgcagg agtcgcaagt gttccaagaa
    13321 caagttacct atctgccttt aacaagatgg ataaaacagc catgtacaat gcagagaaag
    13381 ggtttggatt tggcttgtca ctcttttcca gccgtacctt gaattacgaa cacatgaaca
    13441 aggaaaataa aagtggttgg tatacgagtg atgggatgtt ctatctttac aatggcgatt
    13501 tgagtcacta tagcgatggc tactggccaa cagttaatcc atataagatg cctggtacaa
    13561 cagagacgga tgctaagaga gcggatagcg atacaggtaa agttttaccg tctgctttcg
    13621 ttggaacgag caaactagat gatgccaatg cgacagcaac catggatttc accaactgga
    13681 atcaaacatt gactgctcat aagagctggt ttatgctaaa ggataagatt gcctttttag
    13741 gaagcaatat ccaaaacact tcaacagata ctgctgcaac tacaattgac cagagaaaac
    13801 tggaatcaag taatccatat aaagtctatg tcaatgataa agaagcctcc cttacagaac
    13861 aagaaaagga ttatcctgaa acccaaagtg tctttttaga atcgtccgat tcgaaaaaga
    13921 atattggtta ctttttcttt aagaagagtt caatcagtat gagtaaggct ttgcaaaagg
    13981 gagcctggaa ggatatcaat gaaggacagt cagacaagga agttgaaaat gaatttctta
    14041 ctattagtca ggctcataag caaaatggag attcttatgg ctatatgctc attcctaacg
    14101 tggatcgtgc caccttcaat caaatgataa aagagttaga aagtagcctc atcgaaaata
    14161 acgaaaccct tcagtctgtt tatgatgcta aacaaggagt ttggggcatt gtgaaatatg
    14221 atgattctgt ctctactatt tccaaccaat tccaagtttt gaaacgtgga gtctatacca
    14281 ttcgaaaaga aggggatgaa tataagattg cctactataa tcctgaaacc caggaatcag
    14341 ctccagatca ggaagtcttt aaaaagctag agcaagcagc tcagccacaa gtacagaatt
    14401 caaaagaaaa ggaaaaatct gaagaagaaa agaaccattc ggatcaaaag aatctccctc
    14461 agacaggaga aggtcagtca atcttggcaa gtctagggtt cttgctactt ggggcgtttt
    14521 atttattccg tagaggaaag aacaactaat ttgttcatca tctagatgaa ttacatgaaa
    14581 ctgtggaaaa tagaaaaaat ccgaagaagg ccaaatatct tcggattttt cttttaaaaa
    14641 gggataagtt gatacttatc cttttttact tcattatgtg actatagcgt tttgaaacta
    14701 gaataggacg tcataactgc taaaagattt ctataaattc atttgatttt cctaatcaat
    14761 ttgttcgtat cctatttcac tccactatat tagtccgtct cgctccgtga ggtgcgagac
    14821 aaaacaacca cccgctatgc gggtgcgcgt cgaaggctat accaaaaaac tccaaacgcg
    14881 atacaataaa ggtgttcaat ccaattgtaa agcgaaagga gaaaaaatat ggcacaaaag
    14941 actcatagtt tatcatacac aaagtggatg tgttctatca tattgtgttc acccctaagt
    15001 atagacgaaa agtcatctat aatcaatata gaagtagttt aggcgaaata tttcatcgct
    15061 tgtgtggtta taaaggtgtt gaaatgatcg agggtcactt aatgccagac catgtacaca
    15121 tgttagtcag tattccacta aggctaagtg tttcgagttt catggggtat ttaaaaggca
    15181 aaagtgcact catgatgttt gacaaacacg ccaatctcaa gtacaagttt gggaatcggc
    15241 atttctgggc ggaaggttat tatgtaagta cagtagggct taataaagcc acacttaaga
    15301 aatatagtca agattaaaga aattatcgag tggatgattt cttcacgagt atgaaaattt
    15361 gagaacgagt aaagtatgat atatagtaaa atgaaataag aacaggacaa aatcgatcag
    15421 gacagtcaaa tcgattttta acaatgtttt agaagtagag gtgtactatt ccagtttcaa
    15481 tctactatag cactagataa attgagtgta aaagaatatg aggatccctt tagggatagt
    15541 ggtaagtaat accaaagtct cttaaagagg caagtgacga gtcaagagca ataaggcttg
    15601 aacaacgtga aagccagcgt ctttaggcgc tggctggtaa tttgggctta tagctctggg
    15661 ataaaccacc cgtttgacgg gtggttatga ttttatctga gtgtaacata ctgttgggca
    15721 atctcgctga tgcggtcaaa gttgccttgg gaagcgagtt tattgagttc gccaccaatt
    15781 ccaacggcgt ctgcaccagc agcgaaccat tgagggatgt tgtttagacc gactcctccg
    15841 gttaccatta cggaaacttg tgggatcggt gccttgactg cagagatata tgctggactg
    15901 agagcactac ctgggaagag tttgatgatt tcactaccgg cttcaagtgc agtcgtgatc
    15961 tctgtgaggg taatacagcc tggaatgtac ggtgtgctgt agagattgca cattttcgca
    16021 gtttcagcat ggaaagatgg agaaacaacg taatttgctc cggctagaat ggcatctcta
    16081 gcagttacgg catcaagcac agtacctgca ccgatacaaa cactctgatc gtcctgatac
    16141 aagtctacaa gttccttgat gatttgtcct gcatactgat tggtataggc gatttcaata
    16201 gctttgatac cgcccttgat acaagcaatc gaggcttgca gtccttcttc ctttgtattt
    16261 cctcgaatga cagcgacaat tttctgtttt tttagttcaa taatcgtatc tgatttggtc
    16321 atgtaattct cctaacgaat gatatcttgt gcatttgcca gtaaattttc aatactagtt
    16381 gcggaagtgg agagatggtc tcctggaaga gtgcatttga gagttgcgct cgcaactgca
    16441 aagtcaatgg tagtttttag ggaggaatga tggagtagtt ggtaaagggc accagatata
    16501 aaggcatccc cgctaccaat tcgttgatag actgcagttt ttagttggac agactcttca
    16561 aatcgttctt ccagagcata ggcttgatag acatttttgt cttgctcatc actagagcgg
    16621 agggtatgga aaatggcctt gaaaccatag gcttctttta aaagtcgcat gcgattttcc
    16681 acctcttcta ggctagcact gtctcttgga aacatctcta gattttggtc atcaatcatg
    16741 agaggatcaa taccgaagca atagtcagta aaacgtgcaa acttagaaaa ttcatacttg
    16801 gcttctagga ctgaaatcat ctttgttctc agattgagat ccattgaaac gacaattcct
    16861 cggcgcttgg cttcttccaa gagtaggaga aggatcgcac ggacctcttg accgatagct
    16921 acggtgattc cactaaaatg aaaatggcta atcccctgaa agagagaatc catatctagc
    16981 atgtttggcc gaatctggct gatactcgta tgcttacgat cgtagaaaac ttcactttga
    17041 cgacaaccaa agccgttctc caaatagtag aggccgattc gatcgccaag ccgacagatt
    17101 gaactggtat cgatttggtg ctgtttcaag aatgtgagaa aacgatctcc aatctcgttg
    17161 gcagggagtg cggtaaagac tttcgttgag atacccaggg cttgcaaatt acaagcgatg
    17221 ttaatttctg atccgccaaa ataagtcgaa ctggcaacat gatcgccgat actggtggca
    17281 tctaatggtg agattcgaat taatggttcg ccaaacagta atattttcgt catccattag
    17341 ttcctttctg gtttagaata gctttacttg gctaatactt ctttcaaata agcagcgact
    17401 tcatcatctt ggcagttttc aaagaagtat tcttggaaat atttgccaga gatggtgtct
    17461 ttgaggaagt cttggtcgat tgttttaagg atggtcatca aatcattgtg ggtgatttgt
    17521 ttcacctcgt ttaagatacg agcgttgcgt tgttcaggga ttacacgttc tcttgggtag
    17581 ccaccgccca tttcttcagc aaataagcgt tcaaacatca atttgagggt cagttctgcc
    17641 ccccagccaa atcctttggc ataagggata gacaaggcgt taccaccatt gatttgagaa
    17701 taaaggtaag cgtcagttgg gtccactgct agaccacaga caacaccagg gaagctgttt
    17761 aaagcaagca tagcccctac acccgtacca cagccggtaa caacaaagtc aactgccttt
    17821 gtatttaaaa ggatggcagc cattagtccg ttctgcacat aagttaattg actttctcct
    17881 tcttctccac gcataccata gttaaataat tggtagcctt ttttatctgt cgcttctttt
    17941 agactatcgt aaataatgtg attcttgcta gcttgactat tttcattgat taatgcgatt
    18001 ttcataagat cttctttcta tttttactca ggttgttttc cgatgtaggc taagataccg
    18061 ccatctacat ataggatgtg gccattgaca aaattgctgg catcactagc gagaaagaca
    18121 gcagggccca tcaaatcttc aggatttccc caacgtgcag caggtgtttt tgcaatgatg
    18181 aactggtcaa atgggtggcg agaaccatct tcttgcaact cacgaagagg tgctgtttga
    18241 ggagtggcaa tataacccgg tccaattccg ttacattgga tattggctcc accgtattca
    18301 gacgcaatgt tgcgggtcaa cattttcaag ccccctttag cagcagcata agcgctaact
    18361 gtttcacgtc ccagttcgct catcatcgaa caaatattga taatctttcc atgccctttc
    18421 tttatcatag aaggaataac tgcctttgaa acgataaatg gtgcgtttaa gtcaatatcg
    18481 atgaccttac ggaaatcagc ggcgctcatt tcgcacattg gaactcggcg gataatacca
    18541 gcgttattaa cgaggatgtc aatgacacca acctcttgtt cgatttgctt gaccatggct
    18601 tggataccgt cctcgtctgt cacgtcacag acatatccat gggcttcgat gccaacttca
    18661 cgataagctt caatcccttt attgaccaga tcttgattga tatcgttaaa gacaatagta
    18721 gcgccggctt cagcgtagga tttggcaata gcaaatccaa ttccataaga agcgccggtg
    18781 atgagagcaa tttttccttt taaagaaaac tgctcaattg agaatgatgt atttgtcatt
    18841 tgatacttcc tttcaaattt gttaagactt ctctataacc aaattatatt ctagtaaacc
    18901 ggttttgtca ataaataaat atttttattt ataaa
//
LOCUS       DBEJKC010000036        18569 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.036, whole genome shotgun sequence.
ACCESSION   DBEJKC010000036 DBEJKC010000000
VERSION     DBEJKC010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18569
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.036"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(68..1099)
                     /locus_tag="ACL3G6_001361"
     CDS             complement(68..1099)
                     /locus_tag="ACL3G6_001361"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HGR0545880.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLSHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIKTGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(1354..2037)
                     /locus_tag="ACL3G6_001362"
     CDS             complement(1354..2037)
                     /locus_tag="ACL3G6_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HGR0545881.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGSDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(2049..2993)
                     /locus_tag="ACL3G6_001363"
     CDS             complement(2049..2993)
                     /locus_tag="ACL3G6_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGR0545882.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            3125..5956
                     /gene="uvrA"
                     /locus_tag="ACL3G6_001364"
     CDS             3125..5956
                     /gene="uvrA"
                     /locus_tag="ACL3G6_001364"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HGR0545883.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            5949..7010
                     /locus_tag="ACL3G6_001365"
     CDS             5949..7010
                     /locus_tag="ACL3G6_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGR0545884.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            7142..7540
                     /gene="spx"
                     /locus_tag="ACL3G6_001366"
     CDS             7142..7540
                     /gene="spx"
                     /locus_tag="ACL3G6_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HGR0545885.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            7606..8175
                     /locus_tag="ACL3G6_001367"
     CDS             7606..8175
                     /locus_tag="ACL3G6_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP0191 family lipoprotein"
                     /protein_id="HGR0545886.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            8262..8528
                     /locus_tag="ACL3G6_001368"
     CDS             8262..8528
                     /locus_tag="ACL3G6_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HGR0545887.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            8532..8951
                     /gene="ruvX"
                     /locus_tag="ACL3G6_001369"
     CDS             8532..8951
                     /gene="ruvX"
                     /locus_tag="ACL3G6_001369"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HGR0545888.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            8967..9272
                     /locus_tag="ACL3G6_001370"
     CDS             8967..9272
                     /locus_tag="ACL3G6_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HGR0545889.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            9531..10781
                     /locus_tag="ACL3G6_001371"
     CDS             9531..10781
                     /locus_tag="ACL3G6_001371"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGR0545890.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKDGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMREGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            10865..11320
                     /locus_tag="ACL3G6_001372"
     CDS             10865..11320
                     /locus_tag="ACL3G6_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0198 family lipoprotein"
                     /protein_id="HGR0545891.1"
                     /translation="MKLKRFTLSLASLASFSLLVACSQRAQQVQQPVAQQVQQPAQQN
                     TNTANAGGNQNQAAPVQNQPVAQPTDIDGTYTGQDDGDRITLVVTGTTGTWTELESDG
                     DQKVKQVTFDSANQRMIIGDDVKIYTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            11466..12998
                     /gene="cls"
                     /locus_tag="ACL3G6_001373"
     CDS             11466..12998
                     /gene="cls"
                     /locus_tag="ACL3G6_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGR0545892.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIMEIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            13076..13219
                     /locus_tag="ACL3G6_001374"
     CDS             13076..13219
                     /locus_tag="ACL3G6_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545893.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            13256..14794
                     /locus_tag="ACL3G6_001375"
     CDS             13256..14794
                     /locus_tag="ACL3G6_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HGR0545894.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     YFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFVHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILY
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            14914..17121
                     /gene="nrdD"
                     /locus_tag="ACL3G6_001376"
     CDS             14914..17121
                     /gene="nrdD"
                     /locus_tag="ACL3G6_001376"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HGR0545895.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTD"
     gene            17133..17273
                     /locus_tag="ACL3G6_001377"
     CDS             17133..17273
                     /locus_tag="ACL3G6_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545896.1"
                     /translation="MGKYQLDDKGCAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            17317..17823
                     /locus_tag="ACL3G6_001378"
     CDS             17317..17823
                     /locus_tag="ACL3G6_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0545897.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            17816..18406
                     /gene="nrdG"
                     /locus_tag="ACL3G6_001379"
     CDS             17816..18406
                     /gene="nrdG"
                     /locus_tag="ACL3G6_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HGR0545898.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            18414..>18569
                     /locus_tag="ACL3G6_001380"
     CDS             18414..>18569
                     /locus_tag="ACL3G6_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside-triphosphate reductase"
                     /protein_id="HGR0545899.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNPNY"
BASE COUNT         5541 a         3511 c         4258 g         5259 t
ORIGIN      
        1 tgctgtaata tgtgatgaaa ataccagtaa tgataccgag aaaaaagctg agaaactttt
       61 cccagcttta tttgttatag tcaaagcgaa tgacttgttc ctgtgcatct acatgagcat
      121 ggaccccaaa gggtacaatt gctcttggag ttgcgtggcc gacattcaga ttatagacaa
      181 tcgggatatt gctgtcaatg atatccaata gtgcctcttt atagtcgtca tggaaagttt
      241 catccatagg ttttccgacc aagagtccat tgatgaccgc gaatatgcca gtgtccttta
      301 aagttagcaa catctttttg aagtcttctg gcttaggctt ttcttcgctt gtttcgagca
      361 agaggatttt cccttcccag tctgacaagt cagggaaaag tttgtatttt tggcagagtt
      421 ccgtgctatc tgcgtatcga gagttgtcaa agatatcgta gagggattcg aggcaaccac
      481 cgaggatttt tccctcgaac tgagcacttc cttgcaacaa gtcaaaacct gtatttgtat
      541 gactgacacg aggtgttccc agggccgtgg gactaaaatc agttcgttcc tcataccaaa
      601 cgtcactagg gcggatttct gaaattcttc ccgtcttaat caattcttta aagtagtgaa
      661 ggctataggc tagcatttct ttgtctaatt cacaaatgtc tgctaaaaag gattgaccat
      721 aaaaagtctt gattcctaat ttatgcaaca tgaggtggtt catggttgta tccgagaagc
      781 caagaaaaat tttttgcttg ataacctttt ggagttggtc attttcaaaa agataaggta
      841 gcaagcgata ggtatcgtct ccaccgatgg cacataggat catgtcgatg ctatcatcag
      901 aaaaggcatg aatcaaatcc tctgcacgag cttcaggatg gtccttgata aagtctaatc
      961 cttttaacga atgggacaaa aagatgggat tgagtcccag atccttgaga cgttggatac
     1021 ccaagtccac ttcgtgtttg acaaaatcct ctccgataat gccactagat aaactaacaa
     1081 taccaatagt agaaaccata tctcatcctc ctagaaatag attgagccta ttttatcaca
     1141 aaatataaga gaaagctatg tgggatttca gaagaatact tttaatactc ttcgaaaatc
     1201 tcttcaaacc acgtcagttt tatctgcaac ctcaaagctg tgctttgagc aacctgcagc
     1261 tagcttccta gtttgctctt tgattttcat tgaatataac tcaaaaaagt aagtgaaaaa
     1321 gcaaccgcac ctgcagttgc ttttatcgtt ttcttattct tgatagcgtg ttggtcctgc
     1381 acttgcacta cggatattca agcgtttctt gagatagaag cgaagggcta ggagggctgc
     1441 tccaataata gctagtggca atggatccag tactgggtta aggctagctg gtaggaagct
     1501 tgttgcaaag aagacaagca accaaaggaa catagaagct aggataacta gtacagattt
     1561 ccagaaaggt ggacgttgac tgcgatccat atctgatcca tagtattggt aaacaaagta
     1621 gtacatcaag tagaaggcaa atccaccaac cagtccaact aatagaagag taatcaatcc
     1681 atagccgaaa gcttggtctg ccgcaaagaa ggttgtgagg gcgctgacaa gggcaaagag
     1741 gctagtgatg aaaagagctg agtccataat catcagtttt gggtcatcat tttcttttgg
     1801 atgctctttt tcgtactgct ctttgacagt gaagctatga gcccaatgag ttggtgcgcc
     1861 gtatagggaa cgggcagttg tacctttaga ttgctcctca aggatttggg gaatgacttc
     1921 ctcaaaaata gtctggattt cagcgtctgt tttcccatct ttgatgaatt gttgggtagc
     1981 aatgtggaca aactcttggt ttttcttagt taatttttgt agatcaattt gagacatagg
     2041 aactcctctt agaaccattt tttatggatg agatagagag tgagcgagac actcatagca
     2101 aaggcgataa agacgattaa ccagaaggca tttggctctc cgtttagggg gatttcatta
     2161 tccttaaagt tcatcccgta ggcagaaaag accatggttg ggatggacat gacgatggtc
     2221 acaagggcca aggttttcat gatgttgttc tggttgttag aaatgataga ggcaaaggtc
     2281 tctgtcatag aatgcaagac gtttccataa atatctgcca tctcgatggc ctgttgggtt
     2341 tcaatcaggg tgtcttcaag caggtcttcg tcctcaaggt atttcttgat attgctggtt
     2401 gaactggtca atttcttaat cacgcgctca tttgttttga gggaggcctt gaaatagacg
     2461 atagtttttt ccaattccat gagctcaatc aattcttcat tacgagttga ttgatgcagt
     2521 tgactttcga tttgttcact cttgcggtcg attgaacgaa gggctgttag gtaaagctct
     2581 gcattgcgat aaagaatttg aaagataaaa cgtgaacgca tgaaggtata gaaattacgc
     2641 aatcgacggt tgataaagac atcaaggaca ggtagtggtt ccaaacacgt agtgataatg
     2701 gtttcctcag tgatgataat accaagcggg atggttacgt agtaggtgcg gttatttctt
     2761 tcctccgtga ccggcacgtc tacgataatc agggtatact cgtcttcaat ggtaatacga
     2821 gacatttctt ccgcatcgag cggtgctcga aggtcggcaa tatcaatatc gaaggtgttg
     2881 gcgatttcga gtgattcatt ttgagtcgga ttgacgagat tgatccaagt acccggttca
     2941 agcgtatcga tctctttaaa ttcagttgtt gtagagagaa aaacttgttt catatccctt
     3001 atcctttctc atttttcaga ttttttcaca ctgtactatt atactacaaa atcggccttt
     3061 tgggtaatag aatctcactt tttttggtat aatggtaagc aataatggac tagaaagaac
     3121 aaagatgcaa gataaaattg tcattcatgg ggcgcgtgcc cataatttaa aaaatattga
     3181 tgtggagatt ccgcgagaca agttggttgt cgtgactggc ttgtcaggtt cagggaagtc
     3241 cagtctggct tttgatactc tctatgcgga gggacaacgt cgctatgtag agagtttgtc
     3301 tgcctacgct cgtcagttct tgggaaatat ggaaaaacca gatgtagatg ccattgatgg
     3361 tctcagccca gctatttcca tcgaccagaa aacgactagt aaaaatcctc gctcgacggt
     3421 gggaacgacg actgaaatca atgactatct gcgtctcctc tacgcacgtg tggggacgcc
     3481 ttactgtatc aacggacatg gagctatcaa tgcttcttct gtggagcaaa tcgttgataa
     3541 ggttttggag ttacctgaac gccagcgctt gcagatcttg gctcctgtca tccgcaagaa
     3601 aaaaggccaa cataagagtg ttatcgagaa ggttcagaaa gacgggtatg ttcgtgttcg
     3661 tgtggatggg gaagtctatg atgtgaccga agtgccagag ttgtctaaga gcaagcaaca
     3721 caatatcgat gtcgtggttg accgtattgt tatcaaggag ggcattcgta gccgtctctt
     3781 tgattccatt gaagctgccc ttcgtatcgc agaaggttat gtgattatcg acaccatgga
     3841 cgactctgag ttgttgttct ctgagcatta tgcctgtcca gtttgtggat ttactgtccc
     3901 agagttagaa cctcgtctct tctctttcaa tgctcccttt ggctcttgta gtgagtgtga
     3961 cggcttgggg attaagctgg aggtggatac tgatttggta gtgccagatg ccagcaaaac
     4021 cttacatgag ggagcgctgg caccttggaa tcctatctca tccaactact atccaaacat
     4081 gttagagcag gccatgaaag tctttggagt ggctatggat aagccttttg aggacctgtc
     4141 agaagaagat aagaacttga ttctctacgg ctcagatggt aaggaattcc atttccatta
     4201 tgaaaatgaa tttggtggtg tgcgcgatat cgacattccg tttgagggag ttatcaataa
     4261 tatcaaacgt cgttaccatg aaaccaatag cgattacact cgcactcaga tgcgtctcta
     4321 catgaatgag ctgacctgcg gaacctgtca aggctatcgt ctcaatgacc aggccttgtc
     4381 tgtccgtgtg ggcggccagc aagggccaca tattggagaa atctcagacc tgtctatcgc
     4441 tgaccacttg gacttggtga gccagttaac tttgtctgaa aatgaagcca tcattgctcg
     4501 tcccattctc aaggaaatca aggatcgttt gaccttcctt aataatgtgg gtcttaacta
     4561 tctaaccctg tcacgttcag caggaaccct ttcaggtggg gaaagtcagc gcattcgttt
     4621 ggcaacccag attggttcca acctatcagg tgtcctctat atcctagacg agccgtcaat
     4681 cggtcttcac cagagggaca atgaccgcct gattgccagt ctgaaaaaga tgcgtgactt
     4741 gggcaatact cttatcgtgg tggaacacga cgaagatacc atgcgtgaag ctgattatct
     4801 gattgacgtt ggtcctggtg ccggtgtttt tggtggtgag attgttgcag caggtacacc
     4861 taagcaagtg gctcgcaaca gcaagtctat cacaggtcag tacttgtcag gcaaacgtgt
     4921 catcccagta ccagaagagc gccgtgtcgg aaatggtcgt tttattgaag tgacaggagc
     4981 gcgtgagaac aacttgcaaa atgtcacggc tcgctttcca ctaggaaaat ttatcgcagt
     5041 gacaggtgtg tcgggttcag ggaaatcgac tctaatcaac agcattctca aaaaagccat
     5101 tgcccagaag ctcaaccgta attcagacaa acctggtaag tttaagacta ttacagggat
     5161 tgagcatgtc gaccgtttga ttgatattga ccagagccct atcggacgga cgccgaggtc
     5221 taacccagct acctatacag gagtttttga cgatatacgt gacctttttg ctcagacaaa
     5281 tgaagccaag attcgaggct acaagaaggg gcgcttcagt ttcaacgtca agggaggtcg
     5341 ctgtgaagct tgctcaggtg acgggattat caagattgag atgcacttct tgccagatgt
     5401 ttatgtggct tgtgaagttt gccacggaac ccgctataac agtgaaaccc tagaagttca
     5461 ctacaaggaa aagaatattt cgcaggtctt ggatatgacg gtcaacgatg cggtagaatt
     5521 tttccaacac attccgaaaa ttcaacgcaa actccagacc atcaaggatg taggtctagg
     5581 ctatgtgacc ttgggacagc cagctaccac cctttctggg ggagaagccc aacgtatgaa
     5641 gttagctagc gaactccaca aacgctcgac aggaaaatct ttctacattc tggatgagcc
     5701 gacgacaggg cttcatacag aggacattgc tcgcctgctc aaggttttag ctcgctttgt
     5761 agacgccggc aatacagtcc tcgtcatcga gcacaatctg gatgttatca agacggcaga
     5821 ccatatcatt gacttgggac ctgagggcgg tgtcggtggt ggaaccatca tcgtaacagg
     5881 aactccagaa gaagtagctg ccaacgaagc cagctataca ggacactatt tgaaaggaaa
     5941 gttacatcat gaataaacgc gtacaagcat ttctagctaa aatgcaagaa aaagaactag
     6001 atggtatcat catcaacaat cttaaaaacg tctattattt gactggtttt tggggctcaa
     6061 acggaacagt ctttatcagc cgtgaccgtc aggtcttagt gacagactct cgctatatca
     6121 tcgcagctaa gcaagaaacc agtggttttg agattgtggc tgatcgtgat gaattggctg
     6181 tcattgcagg aattgttaag gacatgaact tgactcgtat cggttttgaa gatgagattt
     6241 cagtgtctta ttaccaccgt atgcaggcag cttttgcagg tttgaacttg cttccacaaa
     6301 ctcagtttgt ggaaggtctt cgtatgatta aggatgaggc agagattgca gcgattcgca
     6361 aggcttgttc tatctcagac caagctttcc gcgatgcgct tgactttatc aaaccaggaa
     6421 aaactgaaat tgagattgcc aacttccttg atttccgcat gcgtgagttg ggagcatctg
     6481 gcttatcttt tgatacgatc ctagctagcg gtatcaattc ttctaaaccc catgcccatc
     6541 caatgcacaa accagtggag ttgggagaag ccattaccat ggacttcggc tgtctctatg
     6601 accactatgt cagtgatatg acccggacta tctatctagg gcatgttagc gatgagcagg
     6661 cagagattta caatacggtt ctaaaagcta accaagcctt gattgaccaa gctaaggcag
     6721 gcttaggttt ccgtgacttt gacaaaatcc ctcgtgatat tatcattgag gcaggttatg
     6781 gtgactactt tactcacggc attggccacg gtattggtct ggatatccat gaggaaccct
     6841 actttagtca gacttctaca gaaactatta agacaggtat ggccttgacc gatgaaccag
     6901 gtatctatat cgaaggcaaa tatggcgttc gtatcgagga tgatatcctg attacagaga
     6961 caggttgtga attattgacc ctagctccaa aagagttgat agtcatttag ttgtttgtca
     7021 agaaaaaagt acgaaaatga cgaaaaaagt caaaaaaaat taaaaatagg tcgcaagtcg
     7081 gatgtttttt atggtataat agactaaact gatagtaaca tgtagcgaaa ggggtaggta
     7141 catgattaaa atttatacag tctcaagttg tactagttgt aaaaaagcaa aaacctggct
     7201 caatgcccac cagttaagtt ataaagaaca aaaccttggt aaagaaggaa ttacgagaga
     7261 agaattactg gatattctaa ccaaaacaga taacggaata gccagcatcg tttcgtctaa
     7321 aaatcgctat gccaaagccc ttggagtgga tattgaagat ttgagtgtca atgaagttct
     7381 caatctgatt atggaaacac cgagaatttt aaagagccca atccttgtag atgaaaaacg
     7441 cctgcaagtt ggctacaagg aagacgatat tcgtgccttc ctaccacgct ctgtccgtaa
     7501 tgtagaaaat gcagaagcac gtttgcgtgc agctctataa acatcaaggc tgggagcact
     7561 tcccagtctt attctatttt aatttcaaaa agaaagaaga aagaaatgaa aaaaatagtt
     7621 cttgttagtc tagctttcct ttttgtcctg gttggttgcg gacagaaaaa agaaactgga
     7681 ccagctacaa aaacagaaaa ggatacgctt cagtcggcat tgccagttat tgaaaatgcc
     7741 gagaagaata cagttgtaac taagactttg gtcttgccca agtcagatga tggtagccag
     7801 cagacacaaa caattactta caaagacaag acttttttga gtctagctat ccaacaaaaa
     7861 cgtccagtct ctgatgagtt gaagacttat attgaccaac atggagtgga ggaaactcaa
     7921 aaagctcttc ttgaagcgga ggagaaggat aagtctatca ttgaagctcg taaattggca
     7981 ggtttcaaac ttgaaacaaa actattgagc gcaacggaac ttcaaacaac gactagtttt
     8041 gattttcaag ttctggatgt caagaaggct tcccagttgg aacatctgaa gaatattggt
     8101 ttggaaaatc ttttgaaaaa tgaaccaagc aaatatattt cagatagatt ggcaaatggc
     8161 gcgacagaac aatagaaaat ccaaataaat agactgcctg aattgtagaa ggtaaggaat
     8221 tatgctataa tggtactatt ctaaggaaag agggtgttag aatgggattt actgaagaaa
     8281 cagtacgttt taaattggac gattccaata aaaaagaaat tagcgaaact ttgacagatg
     8341 tttatgcttc gttgaacgat aagggttaca acccaattaa ccaaatcgta ggttacgtat
     8401 tgagtggaga ccctgcctac gttcctcgtt ataataatgc acgaaatcaa atccgtaagt
     8461 atgagcgtga tgaaatcgtt gaggaattgg ttcgttacta cctcaaagga caaggagtcg
     8521 atctataacc tatgagaatt atgggattgg acgtcggttc aaaaacggta ggggtggcga
     8581 ttagcgatcc gcttggtttt acagctcaag ggcttgaaat catccagata aatgaagaac
     8641 aaggccaatt tggttttgac cgcgttaagg aattggttga tacttacaag gtagaacgat
     8701 ttgtagtggg cttgcctaaa aacatgaaca atacaagtgg accgcgcgta gaagctagtc
     8761 aagcctacgg agcaaagcta gaagagtttt ttggtttacc agtagactat caggatgaac
     8821 gcttgacaac agtggctgct gagcgcatgt tgattgaaca agcagatatc agtcgcaata
     8881 agcgcaagaa agtcattgat aagttagcag ctcagctgat tttacaaaat tatttagata
     8941 gaaaatttta atataaagga gaggctatgt cacacgatca taaccacgac cacgaagaac
     9001 gtgaactaat cacactagta gatgagcaag gaaatgaaac cttgtttgaa atccttttga
     9061 caattgatgg aaaagaagaa tttggtaaaa actatgttct tctagtacca gttaacgcag
     9121 aagaagacga agacggacaa gttgaaatcc aagcttactc attcattgaa aatgaagatg
     9181 gaacagaagg cgaattgcaa ccaatcccag aagactcaga agacgaatgg aacatgattg
     9241 aagaagtctt caacagcttt atggaggagt gatacagtct gggagactgt atcagcccaa
     9301 ctcccagaaa tggggaagag ttggaacgtc cagtgaacat ttttacccca actcttagaa
     9361 cttgagaaga gttggaacat ctagtggatg tttttagccc atattcacat tcatagtagc
     9421 tagttattag ctaaccaggt aagaggtcgg gacgaaaatc ctggccttgt ttttattagt
     9481 aaccatactt taatgcgata attgattgga cttttgtcaa ggagatgtgt atgtttgaag
     9541 tagaagaatg gctccatagt cggattggtt tgaattttcg atcaggtttg ggccgaatgc
     9601 agcaagcggt ggatttgtta ggaaatcctg agcagtctta ccctattatc cacgtaacag
     9661 ggactaatgg gaaaggatct accattgctt ttatgaggga attatttatg gggcatggca
     9721 aaaaagttgc gacctttacc tcccctcata tcgtctctat caatgaccga atctgcatta
     9781 atgggcaacc tatagcagac gcagacttta tccgtttgac tgatcaggtc aaagagatgg
     9841 agaaaacgct tctgcaaact cctgcccagt tgtccttttt tgaattgctg accttagttg
     9901 cttttcttta ttttagggag caggaggtgg atttggtttt attagaagtg ggaattggtg
     9961 gcttacttga cacgaccaat gtggtaactg gagagcttgc tgtcatcacc tccattgggc
    10021 ttgaccatca agaaaccttg ggtgatagtc tagaagcaat tgcagagcag aaagctggta
    10081 ttttcaagga tggtaagaag gcagtgattg cgaaattgcc tccagaagct aggcttgtct
    10141 gtcagaaaaa agccgaatct ttagctgtta acctttatca ggcaggtcaa gattttttaa
    10201 tgctgaatgg tgatttttca agctctttac taaatctttc acagctgaac ataggcttag
    10261 aaggagtcta tcagcaggag aatgcagcct tggcgttgca aacttttctt ctttttatga
    10321 gagaaggaaa ggaagctgtt gatgaacagg ctgtaagaaa ggccttggaa cagacccatt
    10381 gggctggtcg cttggagcgt attcgcccac agatttactt ggatggtgct cataacctcc
    10441 ctgccttgac tcgcttggtt gagtttatca aagaaaaaga gcaggaaggc tatcgacctc
    10501 aaatcctctt tggatccttg aaacggaagg attatcaagg gatgttgggt tatctgactg
    10561 aaaatttacc tcaagtggaa ctcaaaatga ccggctttga ctatcaaggg tctttggacg
    10621 agacagatgt cacaggttac catgtaattc cctcttaccg agaatttatc agcagtttcg
    10681 aagaaagggc agacgctcaa gacttgctgt tcgttacagg gtctctctat tttatctcag
    10741 aagtacgggg ctacctgctg gaccgtgagc agataaattg acccccttgt ttgaacttgt
    10801 tatactaggg gaattgctgg ttagagaaaa tttctctaaa ttggtagcag aaaggaaatt
    10861 catcatgaaa ttaaaaagat tcacactttc tcttgcttct ctagcaagtt ttagtctctt
    10921 agtagcttgt tcacaaagag ctcaacaggt tcaacagcct gttgctcagc aggtccaaca
    10981 gcctgctcaa cagaatacca atactgcaaa tgcaggaggt aaccaaaatc aagcggctcc
    11041 agtacaaaac caacctgttg ctcaaccgac cgatattgat gggacttata ctggtcagga
    11101 tgacggagac cgtatcactt tagtggtaac tggaacgact ggtacatgga ctgagctcga
    11161 atctgacggg gatcagaaag tcaaacaggt tacatttgat tcagcaaatc aacgcatgat
    11221 tattggcgat gatgtcaaaa tttacactgt aaacggtaat caaatcgtcg tagatgatat
    11281 ggatagagac ccatcggacc aaatcgtttt aactaaataa gactatgcaa gtagaaaggg
    11341 ctggattttt cagccttttt acttttacct agaaaataat cataaatact tgccttctac
    11401 cgaatacctg cgttatacta gtatcaatta cttgttttta gcattcaaac tatcaaggag
    11461 gggatatgaa atataggaaa tttcaattat tgatgtccaa gtatggcttt agtctttcga
    11521 ttatgctact tgaactttgt cttgtttttg gtctctttct ttatttagga cgcatggctc
    11581 ccattttatg gattactgtc ctcattctac tgagtatcat cacaatcatt tcgatagtca
    11641 accgtaatac gactcctgag aataaggtaa cctggttgtt agtagccttt gtgccagtat
    11701 ttggtccctt gctctatctg atgtttggtg aaaggcgatt gtccaaaaaa gaaatcaaac
    11761 aactgaagaa gctaggctct atgcatttcc aagaagcaaa tagccagcta ctaaaagaga
    11821 aattaaaaga aagtgacaag gcagcttatg gagtcatcaa gtccttattg agtatggata
    11881 ccaatgctga catctatgat caaactgcct ctacattttt tcctaacgga gaagctatgt
    11941 ggaaaaagat ggtagaagat cttaaaaagg ctgagaaatt tattttcttg gaatattaca
    12001 ttatagaaga aggtttgatg tggaatcgca tactagatat actagagcaa aaggtagctc
    12061 agggtgtaga ggttaagatg ctctatgatg atatcggctg tatggctact ttaacaggag
    12121 attatgcaca tcgacttcgt cagctgggca tcgaggccca taaattcaat aaagttattc
    12181 ctcgtttgac agtggcttat aataacagag atcatagaaa aatattgatt gttgatggtc
    12241 agatagccta tactggtggg gtcaatctgg cagatgagta cattaaccac gtcgagagat
    12301 ttggttattg gaaggatagt ggaattcgct tagacggact agcagtaaaa gccctgacac
    12361 gcttattttt gaccacttgg tacattaatc gaggagaaat tagtgatttt gatcaatatc
    12421 atttagaaaa tcattctatc ccgagtgacg gtttaaccat tccatacgga agtggaccca
    12481 agccaatttt tcgagcgcag gtagggaaaa aagtttatca gagtttaatc aatcaagcaa
    12541 cggaatcggt ctatattacg acaccttatt tgattataga ttatgattta acagagacaa
    12601 tcaaaaatgc agctatgaga ggggtcgatg ttcgaattat caccccttac ataccagata
    12661 agaagttcat tcagttagtc acgagagggg cttatcccga ccttctttct gctggtgttc
    12721 ggatttatga gtatagtcca ggttttattc atagtaagca gatgttggta gacgaagatt
    12781 ttgcggtggt ggggacaatc aatctcgact accggagctt ggtacaccat tatgaaaatg
    12841 cagtcttact ctataaaact ccttctataa tggaaatcgc ccgagatttt cgaaatatat
    12901 ttgcagattc tcaggaagtc tatcctcatt ctatcaaaac gagctggtat caaaagcttg
    12961 taaaagaaat cgcccagcta ttcgccccta tcttataaga aatctagaac ttaggataca
    13021 aaccagacct atttttcttg tcttttacga atagaaagaa agaggagggg aattcatgct
    13081 aactaaggaa gaagtgaatg atatgattga gttcaaacag acacatttac accgctttcg
    13141 ggaaattgaa acctttgtga aactatgcaa aaaatcactc aaacagccat cgcaagctga
    13201 caatcctagg actttttgat atactaagac agataaattg aacaggagaa acgatatgag
    13261 tgtgtatggt agagtagaag aagttcataa ggagaatcgt gaacctctag aataccaaat
    13321 cgaacaagaa tcgcatcatc gtgaatcaag tcgtcttcct ttggtgaaaa ttttactatg
    13381 gagtacgctt gtaacgggga taactctagg agtaccgcta ttactcgact taatgagtgc
    13441 acaagaagtg caggattttt atgcaggttg ggcgcttcat cagacaggga agatttacag
    13501 cgactattat ggaagtcaag gtttgcttta ttatttgctg acttacgtga gtcagggcgg
    13561 atatttcttt gccatctttg agtggttagc cttggtagca ggaggatttt tcctttttag
    13621 atcagcggac accttgacag agcaaggaga ccaagctgga catctggtga ctatttttta
    13681 catgctagtt acaggtcttg cttttggtgg aggctatgcg actcttttag cgcttccttt
    13741 cttattcgca gcctttagtt tagttgcggc ttacctaagc aatccaagcc atgataaggg
    13801 atttgtacgg attgggctag ctttggcagg cggatttttc tttgctccct tatcatcgct
    13861 cctgtttatt gctgtagtga gtttaggctt gttggtcttt aaccttgggc atagacgttt
    13921 tgtgcatggg ttttatcagt ttcttgcagt ggctttaggt ttttcacttg tcttttatcc
    13981 aactgcctac tatagtgctg caacaggaag ttttggggat gcgattagtg gtattcgtta
    14041 tcctattgac agtattcgct ttgattttac ttctaaaatt ttagagaata tgttttttta
    14101 tggcttgttg tcccttggtt tgggatttgt ggtttgtatc tttttaggtc tctttcaatc
    14161 caaacccttt aaactatacg tcatttcggt tcctgcaagt cttgtggtaa ttttaggttt
    14221 gattttactt ttcttttcac aagagcctct gcacgcttct tatttgatgg tcgtcttccc
    14281 tgttttccta cttttattgg taaccaatat taagagtcaa cagagggggc gtagtgctag
    14341 aagaagccga agagaaacgc cagttagcct atggagtcgt ttcttcaaag gaaatctata
    14401 tctgctagtt tttgggtttg tctatctttt gtctgttcct tttttgatga agtttgtcct
    14461 ttatccagta ccttatcaag aacgtaatcg tcttgctgat ttggtaaaag aggagacaaa
    14521 tacggaagat gctatctatg catgggatga tactgcgact ctttatcgta agagtgagcg
    14581 cttgtcgcca tcggcgattt tgtacccgtt gcactataca gcaactgaag aaaatcgtaa
    14641 taagttactt aatgacttga aagaaaaaca acctaaggtg attgtggtaa atgacaaggt
    14701 ggtagtctgg tctgaagtgg aaacactctt aaaagaaaat taccaacaag taaagactga
    14761 ttactcagag tttaaagtct ataaaattaa ataaccaaat caatatcttg tgtattttta
    14821 aaaattttag gatttttaac acaagatatt gatttttctt tttagagtgg tataatactt
    14881 tttagaaaga acattttaga aaagagcatg catatgattg cactagaaga aaaaattaca
    14941 attttgccaa ctctcttcgt cgagaaacga gatgggagac gtgttgtatt tgatgtggac
    15001 aagattgaca aggctctcca caaggcggct gacaaggtta tggatgtgac acccctggtt
    15061 gaaaaacgcc tcaatgatct gactgagcga attattacag aaattcatag tcgctttcca
    15121 cagggaatta agatttacga aattcaaaat atcgtagaac atgaactcct tgaagccaaa
    15181 gaatatgcac tggctgagga gtatattact tatcggacac agagggattt tgagcgctca
    15241 aaagcgacgg atatcaactt tagtattcat aaacttctca acaaagacca gacagttgtc
    15301 aatgaaaatg ctaataaaga cagtgatgtc tttaacactc agcgtgattt gacagcaggg
    15361 attgttggga aatcaatcgg actgcaaatg cttcctaagc acgtagccaa tgcccaccaa
    15421 aagggggata tccactatca cgatttggac tacagtccct atacccctat gaccaactgc
    15481 tgtttgattg attttaaggg tatgttggaa aatggtttta agattggaaa tgcagaggta
    15541 gagagtccca agtctatcca gactgcgaca gcacagattt ctcaaatcat tgccaacgtt
    15601 gcttctagcc agtacggtgg ctgttcagct gaccgtatcg atgaaatttt ggcgccttat
    15661 gcagagaaga actatcaaaa acatctcaaa gatgcagaag agtgggtatt gcctgaaaaa
    15721 cgggaagatt acgcttggaa gaaaacgcaa aaggacatct acgatgccat gcaatctctt
    15781 gagtatgaaa tcaatactct cttcacttca aatggacaaa caccttttac ttcgctaggt
    15841 tttggtctgg gaaccagtcg ttttgaacga gaaattcaaa aagctatttt aaacattcgc
    15901 atcaagggtc ttggttcaga acaccgtacg gctatctttc ctaaacttat tttcactctg
    15961 aaaagaggcc ttaatttaga ggaaggaact cccaactacg acatcaagca gttggctctt
    16021 gagtgtgcaa ccaaacggat gtatccagat gttttatctt acgataagat tgttgacttg
    16081 acaggatcct tcaaggtgcc tatgggttgc cgttctttcc tccaaggatg gaaggatgaa
    16141 aatggtgtag aagtcaattc aggtcgcatg aatctgggtg ttgtgacggt taatctgcct
    16201 cgtattgctc ttgagtctga aggtgatatg aataagttct gggaaatctt caacgagcga
    16261 atgaatatcg cagaagatgc tcttgtttac cgtgtcgaac gcactaaaga ggcgacacca
    16321 gcgaatgctc ctatccttta tcagtacggt gcttttggcc atcgtctagg taaagaagaa
    16381 agtgttgacc agctctttaa gaatcgtcgt gcgaccgttt cgctgggcta tatcggcttg
    16441 tatgaagtag cgacagtttt ctttggtaac agctgggaaa gtaatccaga tgctaaggaa
    16501 ttcacgctag acatcattca cgatatgaaa cgccgtgtag aagagtggtc agaccaatat
    16561 ggctaccatt tctctatcta ctcaacacca tccgaaagtc tgacagaccg tttctgtcga
    16621 ctagatatag acaagtttgg ctctattcct gatatcacag acaaggaata ctacaccaac
    16681 tctttccact acgatgttcg taaaaatcca acaccgtttg aaaaattgga ctttgagaaa
    16741 gtctatccag aagcaggtgc gtcaggtggt ttcatccatt attgtgagta tccagtcctt
    16801 cagcaaaatc caaaggcctt ggaagctgtc tgggattatg cttatgaccg tgtaggctat
    16861 ctaggcacca atactccgat tgaccgttgc tacaagtgtg actttgaagg ggattttgaa
    16921 ccaactgaga gagggtttgc ttgtccaaac tgtggcaata gcgaccctaa aacagtagat
    16981 gtggtgaagc gaacttgtgg ctacctaggt aatcctcaag caagaccgat ggtcaacggg
    17041 cgtcacaagg aaatcgctgc gcgtgtcaaa catatgaatg gttcaacgat taaaatagct
    17101 gggcatcaag taacagatta gaaagaaatg aaatgggaaa atatcaacta gacgataagg
    17161 ggtgcgcaca agtgacccgt tatcacgaga aacactctaa aggtggagct ggtaagaaag
    17221 aacgcttgct tagcttcaga gaacaatttt taaacaagaa caagaaaaaa taaaagtgag
    17281 agccagctct cgcttttctc atagtgggag gtaaggatgg aattacgcag accaagatta
    17341 gcggataaga aagctgtttt agatatgatg acagagtttg aaaaatttca gtcgcctcac
    17401 gacggcggtt tctgggatac agagaacttt gtgtatgaag actggttaga aagcaatcag
    17461 gaacaggaaa tggggattaa tctgcctgaa ggatgggttc ctgcaattca gttagtggct
    17521 ttttctgaga aaggtcaagc agttggattt cttaatctcc ggttgcgcct cagtaacttt
    17581 ctactagaag aaggtggcca cattggctac tccattcgtc catctgaaag aggcaagggt
    17641 tatgcaaaag agactctccg tcagggcttg caagttgcta aggaaaagaa catcaagaaa
    17701 gctctggtga cctgtagcgt gaataatcct gctagcagag cagtcattct agcaaatggt
    17761 ggaatatttg aggatgctcg caatggagtc gagcgttatt ggatagaggt agcgaatgaa
    17821 taatccaaaa ccacaagaat ggaaaagcga ggaacttagt caaggtcgta tcattgacta
    17881 caaggccttt aactttgtgg acggcgaagg cgtgcgtaac tctctctatg tatcaggctg
    17941 tatgtttcac tgcgagggat gttataatgt tgcgacttgg tcttttaatg ctggcattcc
    18001 ctatacagca gaattagaag agcagatcat ggcagatctt gctcagccct atgttcaagg
    18061 tttgactttg ttgggagggg agccttttct taatactggg attctcttgc cacttgttaa
    18121 gcggattcgg aaggaattgc cagacaagga catctggtcc tggaccggct acacttggga
    18181 agaaatgatg ttggaaactc cagataaact ggaattcttg tcactgattg acattcttgt
    18241 cgatggaaga tatgatcgaa ctaagagaaa tcttatgctc cagtttcgag gttcatctaa
    18301 ccaacgaatt atcgatgtgc aaaaatcgct caaaagtggg caagtagtga tttgggacaa
    18361 gctcaatgac ggaaaagaaa gctatgaaca ggtgaagaga gaatgaagaa aaaatgaaga
    18421 aaaaagactt agtagaccaa ctagtctcag agatcgagac ggggaaagtc aggacactgg
    18481 gaatatacgg tcatggagct tcaggtaaat caacctttgc acaggaattg taccaagctt
    18541 tagattctac tacagtaaac cccaattat
//
LOCUS       DBEJKC010000037        18396 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.037, whole genome shotgun sequence.
ACCESSION   DBEJKC010000037 DBEJKC010000000
VERSION     DBEJKC010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18396
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.037"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(1..104)
                     /locus_tag="ACL3G6_001381"
                     /pseudo
     CDS             complement(1..104)
                     /locus_tag="ACL3G6_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(150..383)
                     /locus_tag="ACL3G6_001382"
     CDS             complement(150..383)
                     /locus_tag="ACL3G6_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGR0545900.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            complement(389..1381)
                     /gene="plsX"
                     /locus_tag="ACL3G6_001383"
     CDS             complement(389..1381)
                     /gene="plsX"
                     /locus_tag="ACL3G6_001383"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HGR0545901.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIVGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(1378..2148)
                     /gene="recO"
                     /locus_tag="ACL3G6_001384"
     CDS             complement(1378..2148)
                     /gene="recO"
                     /locus_tag="ACL3G6_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HGR0545902.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(2145..3314)
                     /locus_tag="ACL3G6_001385"
     CDS             complement(2145..3314)
                     /locus_tag="ACL3G6_001385"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR0545903.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLKDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            3463..4473
                     /locus_tag="ACL3G6_001386"
     CDS             3463..4473
                     /locus_tag="ACL3G6_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HGR0545904.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVINAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            complement(4492..4617)
                     /locus_tag="ACL3G6_001387"
     CDS             complement(4492..4617)
                     /locus_tag="ACL3G6_001387"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545905.1"
                     /translation="MKIKEQTRKLAAGCSKHRFEVADRTDEVSNIYLRQGDVDVV"
     gene            complement(4658..5095)
                     /locus_tag="ACL3G6_001388"
     CDS             complement(4658..5095)
                     /locus_tag="ACL3G6_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HGR0545906.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(5180..7813)
                     /gene="polA"
                     /locus_tag="ACL3G6_001389"
     CDS             complement(5180..7813)
                     /gene="polA"
                     /locus_tag="ACL3G6_001389"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HGR0545907.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNMSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDQLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEIKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            8066..8976
                     /locus_tag="ACL3G6_001390"
                     /pseudo
     CDS             8066..8976
                     /locus_tag="ACL3G6_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603333.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            9104..9246
                     /locus_tag="ACL3G6_001391"
                     /pseudo
     CDS             9104..9246
                     /locus_tag="ACL3G6_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9383..10351)
                     /locus_tag="ACL3G6_001392"
     CDS             complement(9383..10351)
                     /locus_tag="ACL3G6_001392"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGR0545908.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(10496..11310)
                     /locus_tag="ACL3G6_001393"
                     /pseudo
     CDS             complement(10496..11310)
                     /locus_tag="ACL3G6_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
     gene            complement(11335..11832)
                     /locus_tag="ACL3G6_001394"
     CDS             complement(11335..11832)
                     /locus_tag="ACL3G6_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HGR0545909.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(11905..13266)
                     /gene="radA"
                     /locus_tag="ACL3G6_001395"
     CDS             complement(11905..13266)
                     /gene="radA"
                     /locus_tag="ACL3G6_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016893792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HGR0545910.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(13280..13795)
                     /locus_tag="ACL3G6_001396"
     CDS             complement(13280..13795)
                     /locus_tag="ACL3G6_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR0545911.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(13797..14240)
                     /locus_tag="ACL3G6_001397"
     CDS             complement(13797..14240)
                     /locus_tag="ACL3G6_001397"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HGR0545912.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(14297..14394)
                     /gene="ffs"
                     /locus_tag="ACL3G6_001398"
     ncRNA           complement(14297..14394)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACL3G6_001398"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(14427..14894)
                     /gene="tadA"
                     /locus_tag="ACL3G6_001399"
     CDS             complement(14427..14894)
                     /gene="tadA"
                     /locus_tag="ACL3G6_001399"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HGR0545913.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(15095..16381)
                     /locus_tag="ACL3G6_001400"
     CDS             complement(15095..16381)
                     /locus_tag="ACL3G6_001400"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HGR0545914.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(16612..16848)
                     /gene="comW"
                     /locus_tag="ACL3G6_001401"
     CDS             complement(16612..16848)
                     /gene="comW"
                     /locus_tag="ACL3G6_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma(X)-activator ComW"
                     /protein_id="HGR0545915.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            17113..17910
                     /locus_tag="ACL3G6_001402"
                     /pseudo
     CDS             17113..17910
                     /locus_tag="ACL3G6_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(17945..18154)
                     /locus_tag="ACL3G6_001403"
                     /pseudo
     CDS             complement(17945..18154)
                     /locus_tag="ACL3G6_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(18320..18393)
                     /locus_tag="ACL3G6_001404"
     tRNA            complement(18320..18393)
                     /locus_tag="ACL3G6_001404"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18357..18359),aa:Asn,seq:gtt)
BASE COUNT         5571 a         4456 c         3191 g         5178 t
ORIGIN      
        1 ttgagtttgc tggatttacg tggagtttgt gcttgaggat atatcttcat gagcccttga
       61 taaccactgt cagccaagat tttaccagct tgtccaatat ttctcatttc taaaaaccat
      121 ctacttccgt tgacttggaa ctccgattgc tattttcctt gaatgatttt aaccacatct
      181 cctacacttt ggagttggtc aatttcctca tcgctgattt cgatactaaa ttcatcttcc
      241 agagtcaaga taaactccat caagtcaaca gaatccgcat ccaaatcgtc tttcagactc
      301 aaggattctg tcacgacaaa gtcctctccc tgtcgctctt ggataatggt cacaatacgg
      361 tcaaaaattt ctttttctgt catctctttt attctcctga aaattcacgc gcagtctggg
      421 caaccacgtc tgtttctagc atggtacgaa tctgacgaat cgtactataa acagccttgg
      481 catcgcttga gccatgagtc ttgacaacag gtgccttaac accaaacaag accgctccac
      541 caacatctga ataattgagc tgttttttca aaccactgag gctgtccttg agaaggaggg
      601 cacctagttt cgctcgaaga ccaccacctg taatagctgt cttgagcaag cccacgattc
      661 ccatagctgt cccttcgatg gatttgagca cagcgtttcc cgtgaaacca tctgccacaa
      721 caacatctgc aacgccattc atcaaatcac gcgcttccac gtttccgata aagttcaaac
      781 tttcatcagc cgccagtaat tcataagttt ccttacgaag cgggtcaccc ttgctactct
      841 ctgttccgtt gttgagcaaa ccaacgcgtg gttgcgcaat gccacggaca tttttagcat
      901 agaaggaacc tagaaccgca tattgatgga ggtgctgggc tgtattttct gcattggcac
      961 caaggtctag catgtcaaaa ccttttccat caacggtagg caaggtagac atgagtccag
     1021 gacggtcgat attcttgata cgacccacga tgaagaatcc tgctgccaac aaggcacctg
     1081 tattcccagc cgaaaggaca gcgtctgctt caccatcttt gacagccttg gctgccaata
     1141 ccatactggc atttttctta ttcctaatag ctctcgtagg ttcatcatcc gaatcaatct
     1201 tctcatccgt atggataatg ctgacgcgct ctgtcgctgt cagatattgc ttgattttag
     1261 cttcatctcc gtaaagttga acctcgatat ctgaaaagtc agatagggct tgattgacac
     1321 cctcaacaat ggcctgaggt gcgtaatcgc cccccatggc atctactgcg atttttttca
     1381 tttcttttcc tcttttagta attgtcccca gtctgctagg gaatcaataa atttctttga
     1441 ttttaggtga atcccaacgt actcttcata taattgatcc ataaattggc gtagctcttg
     1501 cttgattcca ggcttgagcg aaatggtctc caaagtctca aaatcaatag cttgaaattg
     1561 attgagcaga taggggatat tgggattgag atgacaacgt ctcttatcct catgataatg
     1621 ctctggacag aggcaggctc catatttgaa agaaaagtca aaagcctgac caacccgatg
     1681 gcagaagaca cactcattaa aattgaggct gattccaaat cgagtcaaaa tttgaatttc
     1741 aaaaatattg gtcaaaacct gataatccaa gcctgcttcc atcaactcca aagtcttttg
     1801 caaaaaagca aacaagggag catcctgctg attgtcctgc aaactagcat ctgcaagagc
     1861 tgccacatag gtcgcatagg ccatgacaaa gaggtcacta ttaatcttgg gaaaagtcat
     1921 gacctcatga tagtcttcga tgtaactgag tccgtcatca ttgattcgca agagaaatcg
     1981 tgccaacacc aagggctgaa taacaggcgc cagcttagac tgaccagcgt gtttgacaaa
     2041 aaacatgcgt ttgccaacct gctctgtaaa aattttgacg agcttgtcat cctcacgaaa
     2101 attgcgattg taaagcacca agccttgact cgtgatagac tgaatcatgc ttctctcatg
     2161 tactcctcaa gtcgtttcat ggcttctttg atagtctcca tgctggctgc ataagatagg
     2221 cggacgtagc cttccccgta acgtccaaag gctgcaccag ggataaaggc aacggccttc
     2281 ttctgagcaa aatccttcag aaaagcaaag gagtcttgat tgtagcccgc tggaatttta
     2341 gcaaaaatat agaaggcacc gtctggtttg ataatctcaa aaccaagagc agtcattttt
     2401 tcgatgatat agtcccgacg ctggatatat tccttcttca tgggctccgc atcattttta
     2461 ccagccgtca aggcttctac cgcagcatgt tgcgccatgg tatttgcggc agtgaccaag
     2521 tattggtgac tcttgattaa ctgggctgtg aaggccgcag gagcgaaaat cagccccaaa
     2581 cgccaacctg tcatggcatg cgatttagac aaaccattga taataatagc ctggtctttc
     2641 aacatcgttc ctagagacac atgggcttcg cctgtgtagg tcaattctga gtaaacctca
     2701 tcacagacaa caaaaatttc gtacttgcgt aaaacagctg ccaaggcctc taactgctct
     2761 cgactgtagg taattcctgt cggattggct ggatagttga gaataaccgc tttgagctta
     2821 tcaccctgct ccaaaatggc cttctccaac atctcaggag tcaagacaaa accattttca
     2881 gtcgtatcaa tctcaacaat ttctgcccca actaagttaa caatcggttc atagcctgga
     2941 taagcaggag ctggcaaaag taccttgtct ccctcttcca aaatagccgt caaagtcgca
     3001 gataaagcct ctgtcgcccc aattgtaacc aagatttcat tttcaggagc atagtccagt
     3061 tggtactttt ccttaacaaa gtcactagct gcctgacgta gagtcagcag accactcatc
     3121 cctgtatagt aggattggtt ctgatcaatc gctcgcttgg ccgcctcctt gacatggtct
     3181 ggcgttgtaa aatcaggttc ccccaaggtc aaacgcaaga ccccaggaat ctccgaaata
     3241 gcctggtcaa actgacgaat caacgaaact tgaatcttat ctaactgttt attaaagcgc
     3301 ttagttaagt ccatagatac ctcctacttt caaaacgtat ctctattata ctacaaaagc
     3361 ctcccgaccg caaaaataca ttagagaata gctttccact ttctatttta cttttcctgt
     3421 ttataggtct ataatggtaa tagattttat ttggaggttt ttatgtcatt tctatcaaaa
     3481 aatggagcag gtatcttggc ctgccttctc atttctatcg tatcttggta cttaggagga
     3541 ttcttccctg tgattggcgc gcccgttttt gccattttca taggcatgct cctacatccc
     3601 tttctctcgt cctataaaca actggatgct ggtttgacct ttagttccaa gaagttgctc
     3661 caatatgccg ttgtcttgct tggttttggt ctcaatatct cgcaggtctt cgcagttggc
     3721 caatcttcac tccctgtcat cctgtccact atctcaatag ctctgattat tgcctacctc
     3781 ttccagcgtt tctttgcact ggatacaaaa ctggctacct tggttggagt aggttcttct
     3841 atctgtgggg gttctgccat tgcagcgaca gcgcccgtta ttaatgctaa ggaaaaggaa
     3901 gtagcccaag ccatttccgt tatctttttc ttcaatgtct tggctgcgct catctttcca
     3961 accctcggca cctggcttca tctatccaat gaaggcttcg ccctctttgc agggactgcg
     4021 gtcaacgaca cttcctctgt aacggctgcc gccagcgctt gggacagtct ttaccaaagc
     4081 aataccctcg agtctgcaac cattgttaaa ctcacacgta ctttggccat tatccctatc
     4141 acgctctttc tatcctactg gcaaagtcgc caacaagaaa acaagcaaag cctacaactg
     4201 aaaaaagtct tcccactttt tatcctttac tttatccttg cctctctcct cactacacta
     4261 ctcacctctc taggtgtgtc cagtagtttc tttacccctc tcaaagaact ctctaaattc
     4321 cttattgtca tggccatgag tgctatcggt ctcaaaacca atctggtcgc tatggtcaaa
     4381 tccagtggaa aatccattct tcttggagcc atctgctgga ttgccatcat cctcaccact
     4441 cttggtatgc agacccttat cggcattttc taacactctt cgaaaatctc ttcaaaccac
     4501 gtcaacgtcg ccttgccgta ggtatatgtt actgacttcg tcagttctat ctgcaacctc
     4561 aaaacggtgt tttgagcaac ccgcagctag tttcctagtt tgctctttga ttttcattga
     4621 gtataacaca aaaggtagcc catcagctac ctttttctta tgcttcctca atcaagcgag
     4681 tatgttctct cttgatacag cgattcatca cgatatcatc acatccacca tcacgcaaaa
     4741 tctcttttgc ttctaaactt tcaagtccta gctgtgccca aaaaatcttg gcatcagctt
     4801 tgagaaaatc acgcgccaca tcgggcagaa attcactgcg acgataaaca ttgacaatat
     4861 ctacaggaaa aggaatttca gcgaggctag cataagcctt ttcacccaag atttcgccac
     4921 ctgccgcctt gggattgact gggatgattt tatagccccg agcctgcatt tcctttgtta
     4981 ctcgattgct ggttgtttct tcacggtcag acaaacccac cacagcaagg gttttactcg
     5041 ttgcgagata ctgacgaatc acgccatcac ttggattgat aaattcttga ctcatagaaa
     5101 tcctcctttt tcatcagtat agcacatttt gaaaaggttt gcagaattct actacaaaaa
     5161 aggaggacta gccccctttt tatttagcct cgtaccaggt tgccccttca ttctcatctg
     5221 cgataagagg aacactgagt tgaatggctt cttccatggt ttgtttcacc aattttttta
     5281 tctctaccaa ttcagattta ggcacttcaa ggacgatttc atcgtgcact tgtaacagca
     5341 tcttagtctg ataaccacct gcaaccaagg ctttatccag ctgaatcatg gcaatcttga
     5401 gaatatctgc tgccgaaccc tggataggtg agttgatagc agttcgctcc gcaaaaccac
     5461 gaatattgaa gttgcgcgaa ttgatatctg gcaactcacg gcgacgctta aagagggtct
     5521 ctacatagcc cttatcacgc gcctcccgca ccacttcatc catgtagttt ttaatacctg
     5581 gaaaacgttc aaagtaggta tcaatgtagg ctttggcttc cttacgacta attcccaaat
     5641 tattagacaa gccaaagtct gaaatcccat aaaccactcc aaagttaact gccttggcat
     5701 tgcgacggtc atttgcagtc acattatcag gacgctcaat gccaaagacc cgcatggctg
     5761 tcgaagtatg gatatctgcc ccctcttgga aggccttaat caagtgctca tccttagaaa
     5821 tatgcgccaa aacgcgcaat tcaatctgtg aatagtcaga gctgagtagc acactatcct
     5881 cccactctgg cacaaaagcc ttccgaatca agcgcccttg ttccaatcgg gcaggaatat
     5941 tttgcaagtt tggatccaca ctagacaaac gcccggtctg ggtcaaatcc tgcatatagc
     6001 gagtatgaat ctttccatca gccaaaatcc agtcctgcaa gccaattaca taagtagatt
     6061 gaatcttagc aatttgacgg taatccagga ttttcttaac aatcggagca ataggagcga
     6121 gacgctccaa cacatccact gctgtcgaat aacctgtctt ggttttctta gtgtattcta
     6181 gaggaagtcc caatttctca aagagaagca cgcccaactg cttaggcgag ttgacattaa
     6241 actcctcacc agccagctcg taaatctctt gagtcagttt ttcaatgaca agctcatttt
     6301 cagcctgcat ctcaagcaag gtctctttct tgaccacaat cccagcaatt tccatcttgg
     6361 caaggacaaa agccagaggt tgctccatat cataaagaag ctctaattgc ccattttcgc
     6421 taagtttttc aagtaaaata ggctctgttt ctaccaaaac agcaagttta caagctaagt
     6481 gttccaagaa tttctcacgt tcaggaatgg cctttttaac acccttaccg tagaaagttt
     6541 catcatcaac caagtaagtc tgaccataaa gactagcgat ggtcgcaatt tcattgtcct
     6601 ccacagtcga aaggaggtat ttagccaaac ggatgtcaaa agcaggcgcc tgcaaatcta
     6661 caccaaaacg ttgcaaaaga actttaacct tcttaaagtc ataaactctc agagatgttt
     6721 tttctaagaa atccttgaaa atcgggtctt gcaacagctc aagcttgtct gtggcataga
     6781 gctgatcccc acaagaccag gcaaatccaa ccaaattatc tgtatggtaa ttctcaccaa
     6841 aaagctcaaa gtggaagata gactcttcac tcagcatatc ttgactgatt tggtcaacaa
     6901 tagtaaaatc caaaccctca gccacatcag ctgacgacat atttaaagcc tgcttgagct
     6961 gtttgaagcc catctcatcg tagaatttcc caagattttc aacatctgga ccactataga
     7021 ccaagtcctc taaaccaatc gcaatcggtg ccttggtatc aatggtcgct agtgttttag
     7081 acaaaaaggc ctgttccttg tcattgatga gattttcctt catcttagaa gtcttcattc
     7141 catcaatatt ttcataaatc ccctcaagcg aaccatgctc cagcaagagc ttaatacccg
     7201 tcttttcacc gactttggtc accccaggga tattatccga cttatcaccc atgagcgcct
     7261 tgagatcgat aaactgagct ggtgtgaggc ccatttcttc catgaggtaa tctggcgtaa
     7321 aggcctcaaa ctcagccaca cctttcttgg aaatttcaac caccgtatgc tcatccgtca
     7381 gctgaatcaa atccttgtcc ccactgacaa tggtaatatc aaaaccatcc tgctctgcta
     7441 gcttatccag cgtcccaatg atgtcatccg cctcatactg agccagctca tagtgacgaa
     7501 tccccatatg atccagcaac tcacgaatga aaggaaattg ctcacgaaac tcatcaggag
     7561 tcttggcccg accaccctta tagtccgcat acatctctgt ccggaaggtc gtctttcccg
     7621 catcaaaagc caccaaaata tgactcggct caacccgctc caacaaatga ctcaacatca
     7681 actgaaaacc ataaatcgca ttggtatgca aaccagccgc attcttaaaa cggtccaact
     7741 gctgatacag cgcaaaaaac gcccgaaaag ctacagaaga cccatcaatc aataataatt
     7801 ttttcttatc catacaccca ttataaagga aagaatcaaa aaataccatt gggaagagct
     7861 agagcaagta tttttcaaac tttttccgaa taaatagata gagccagaga atttagtaaa
     7921 cctagattta aaaatgtgct ataatatagt atattgaatc tataatagta caccttgact
     7981 gctaaaatat ttctataaat taatttgact ttcctgatag agttgttcac atcttatttc
     8041 aattcactat agaaggagga aaaggatgat tctcagacat ctgggaatta gcccgaccaa
     8101 tgacttggtt gctaagaaaa ttttcagcaa cccagaaatc acttgtcaat ttatccgcga
     8161 tatgctggac ttgccagcca aaaatgtgac tattttggag ggaagtaaca ttcatgtctt
     8221 gccttccatg ccctactcag cgcaggattt ttataccagt atagacgtct tggcggagtt
     8281 ggataacggt actcaagtaa ttattgagat tcaagtccat catcagaatt ttttcatcaa
     8341 tcacttgtgg gcttacctgt gcagtcaggt taatcaaaat cttgaaaaaa ttcgtcagcg
     8401 agaaggtgat actcactaga tctacaaaca catcgctcct gtttacgtca ttgctatcgt
     8461 ggatagtaat tatttctcag atgacctggc ttttcatagc tttagtatgc gcgaagacac
     8521 aacaggtgag gtattggcga ttaccaacaa tggacaggaa aaccatctgg ttaagatggc
     8581 attcttggaa ttaaaaaata cagagaaacc agcaaagaca aggttcgcaa gccatggttg
     8641 gagtttttcg gcaacaagcc ctttacccag caaccgcaac gagccattag ccaagcaaat
     8701 caactgctgg actacaagag ctggtccgag gaggacagga aaatgtttag tcaactacat
     8761 atgcgagaag aacaagtctt gttagcacag gactatgcct tggaaactgc tagggctgaa
     8821 ggccttgaac aaggactaga gcgtgggaaa gttgaaggaa gggcagaaag gaaacttttt
     8881 gccttcctag acatagtacg ccaaggtctt ctgacttctg aggttgccag ccagcaatta
     8941 ggtatgtcag tatctgaatt tgaggcactg ttgtaaaatg gctccataat atccatagtg
     9001 ggtaaatccc ctatggatat tatggagcct attttgtgta aaaaaaaaag tcccatatga
     9061 cctataatga aaagcgacaa aacaactcat tagaaagaat catatggaac aattacattt
     9121 tatcacaaaa ttactagaca ttaaagaccc taatgtccag attttaaaca tcatcaataa
     9181 ggatacacac aaggaaagcg tcgattcaaa tgctatcact gttcaaaaat gatggtcgct
     9241 gaaacttatg atgacgtaca gtcatatttc ttttcttttt attatatcac agttttaaat
     9301 ctagctttac tagattcacc gctactatct atttattcgg aaaaaagacg aaaaaacctg
     9361 agaatcatct caggcttggt cattaaattt ttttctcaat atcgaaaagt ggagaaagtg
     9421 gtcgtttttc atgaatacgt acgatagcat cccctaggag atgagcgatt gaaatctgct
     9481 caatcttatc aatcaaacgc tcttctggca gatagatggt atccaaaaca accaatttct
     9541 taatagctga tttttggata ttgtccgtag caggaccaga aagaactggg tgcgtacagc
     9601 ttgcatagac ttcaacagca ccagcttccg caagagcatc tgccgcatga caaatcgttc
     9661 cagcggtatc aatcatatca tcaatcaaga tacaagtctt gccttcaacc ttaccgatga
     9721 tgttcataac ttcactagta ttcatcttat caacgctacg acgtttatca ataatagcga
     9781 tagatgtttt caaaaattct gccaacttac gagcacgagt cacccctcca tggtccgggc
     9841 tgacaaccac atagtcagaa ccaaccatac cacgacgctc aaaataatct gcaatcagag
     9901 gagcacccat caaatgatcc acaggaatat caaagaatcc ttgaatttgc gcagcatgca
     9961 agtcgatggt caataaacga tccactccag ctacttcaag catatttgcg acaagttttg
    10021 aagtgattgg ctcacgcgct ctcgcctttc tatcctgacg tgcataccca tagtaaggca
    10081 tgacaacatt gacagattct gcactcgcac gcttcaaagc atctaccata atcaaaattt
    10141 caagcagatt gtcatttaca ggcgaactag ttgattgtaa gataaagacg tgtttcccac
    10201 ggattgattc ttcaatgttg acctgaatct ctccatctga aaattggcga acacttgatt
    10261 tccccaactc tatcccaatc tcctgcgcca cacgttctgc caattcttta ttagaagaaa
    10321 gggcaaacag ctttaaatca gaaaaagaca tgatttcctc cggtatatat gtatagcttg
    10381 tgcttttcac aagattttcc atctaccatt gtagcgcttt ttgcactatt tttcaatcaa
    10441 aaataaaaga agggcaccat atttgtaccc ttgcatcatt cttttgaaaa atattctagg
    10501 tcatcaactc attgtgtttc tcaacaaagc aataagcatg ataaaaacca tagagagcaa
    10561 tagccgtaac cactggaatc gctaaaggca actctgtttc caactccaca aaaggagagt
    10621 taaacaagaa gtgagttccc aaggctaaac ctagaaaaat aaggccctgt ttcttgccaa
    10681 ccttctgtcc tttataggct ctgtaaagca agtaaacacc tactacagct agacctgaaa
    10741 aagtccagtg agaggcaatt cctgagatga tacgctctaa aattcgcgaa atagtaaagt
    10801 caaagccctc tggcaaatcc gtacgaatat aaccaatatc ctcaatcatt tggaatccca
    10861 aaccggaagc aattccaagt aaaaacaaag attttaattt tcgcacagga atcaaagcca
    10921 aaacaaaaac aagtgacaat aatttcaagg gttcttctac caaaggagcc acaatagcac
    10981 tttcaaaggc atttaaaaat ggactatctg ggaaaagaat ccccagtaaa tcatggatat
    11041 aagtattagc aaaactagac aaccagcctg aaaggaacat ccctcccaat aaagacagaa
    11101 tcaaaacctt ctttggcaat tcccattttt cccaatacgg aagagaaaat aaagagccgg
    11161 aatcatgtaa aagagagcta gaaagataga aactcccatt agtccatatt ccgcacctga
    11221 cctcgaaccg tccgtatagt agatggtttc atactgtaaa ccaatacata gcaataaaat
    11281 aaaaataaat aaaatactgc ttttcttcat acactttctt tctaaatgaa gtatttataa
    11341 ttctacgact gtcatacttc ctgtatcaac attgtaaatg gcaccagaga taatgacatc
    11401 gtctggtatt aggggagact cgataagcag ttgcatatcc tcgcgtacac tctcttctat
    11461 atcttggaag ggcaagaagt cctggtctga cacatctaca cctaattcct cttttaaata
    11521 ctcctgaaaa ggttcatttt caaaggtctg agcaccacag tctgtatggt gcaataccac
    11581 aatctctctt gtccccattt gttgctggga aataactagc gaacgaatca tgtcttcagt
    11641 cactcgacca cctgcattcc gcaagatatg agcatcccca agtgccaagc ccagagcttg
    11701 cgcaacgtgc agacgagagt ccatacaggt cacaatagct actcttgttt tgggtttaag
    11761 tggcagattt aactgcccat gtagggcaac ataagcctga ttggcttgca taaactgttc
    11821 aaaatacgac acgattccct ccttgaaaat ttgatagtca aatatttctc ctatcttatc
    11881 atttttaaga gaatttgtca cggattatgc aaagaccttt ttcaagactt cctgaatcgt
    11941 tgtcacgcca atgacctgaa tttccttagg cagagtgatt cctgtcaagg aattcttagg
    12001 tacataaatc ttagtaaagc ccagtttagc agcttcgttg atgcgttgct caatacgatt
    12061 cacgcgccga atctctcctg tcaagcccag ttctccgaca aaacattcct gaggattagt
    12121 tggcttgtct ttgtagctcg aagcaatagc aactgcaaca gccaagtcaa tcgcaggttc
    12181 atccaattta acaccaccag cagatttgag ataggcatcc tgattttgca agagaagccc
    12241 tgcccgtttt tccaaaacag ccataatcaa gctagcacgg ttaaaatcaa gtcctgtcgt
    12301 agtacgcttg gcatttccaa acatggtcgg tgttaccaaa gcctgaacct ccgccaaaat
    12361 cggacgcgtc ccttccatgg ttacaacgat ggaggaacca gtcgccccat ccaaacgctc
    12421 ttctaggaaa acttgactcg gattgagtac ctcaaccaag ccgcccgact gcatctcaaa
    12481 aatcccaatc tcattagtgg aaccaaaacg atttttgacc gctctcaaaa tacgaaaggt
    12541 gtggtgacgc tccccttcaa agtaaagcac cgtatccacc atatgctcca acatacgagg
    12601 cccagccaag gttccttctt tggtcacatg acctacgata aagatggcaa tgttattggt
    12661 cttggccaac tgcatgagtt cagcggtcac ttcacgcacc tgagaaacag acccctgcac
    12721 ccctgaaatc tcaggagaca tgatggtctg gatggaatca ataatgagaa agtctggctg
    12781 gatacgctcc acttctgcac gaacactctg catattggtc tctgcataga gataaaactc
    12841 actatcaata tcacctaagc gctctgcacg tagtttaatc tgctgggcag actcctcccc
    12901 actgacatag agaactgtcc ccacttggga caactgggtt gagacttgta ggagaagagt
    12961 tgatttccca atcccaggat ccccaccgat gaggacgaga cttcctggta ccactccgcc
    13021 tccaagcaca cggttgaatt cctccatctc cgtcttggtt cgattgacat tgatggaagt
    13081 cacctcagct agtttcatgg gcttggtttt ctcacctgtc aaggacacac gcgcattctt
    13141 gacctcggca acctcaacct cttccacaaa agaagaccaa gacccacagt tggggcaacg
    13201 tcccagatat ttaggggaat tatacccaca attttgacat acaaatgtcg cttttttctt
    13261 tgcgatgaca aacctctttc tatatctcta actcacactc aatcacttgg caaaaatcaa
    13321 tcttctcatt tggcacaaac tggcgcatga gcattcgatg agcaacaact accacagtct
    13381 gatgttctcg atacttagac atacattcta gaaaccgaga cttcatttcc gtagctgtct
    13441 catattgaat aggactatta ggaagcaact cccccttgtt ttctaaaaac agtcttctag
    13501 ctgtttcaaa attttctatt cctgttttat agacctgcca ttcatgtaat aaaggctcta
    13561 ctcttaaagg aagacccgta gcacagacca catacgaagc cgtttctaaa gctcttgtga
    13621 ctgcagaaga tacgattatt tcagctgacg agagtaaagg atttttgctc aatttctgga
    13681 cttgctgccg tcccatctca gacaagggtg ccaaatctat cccaaatcct atataagaac
    13741 gctcctctaa ctcacggtaa tctggctccc catgacgtac aaagataatc ttcattctag
    13801 tgccctgtcg atccaaatcc accagttcga acgccatcag ctgcatctcc atctgcaatt
    13861 aagaaagtag caaaaacagc ctggacaata cgttccccaa cttcaagaac aacctcttga
    13921 tctgtgatat tcttcatctg cgcaaaaata tgcccttcat ttccaggatt tccataataa
    13981 tccccatcaa tgaccccaac tgagttaatt aaaaccaagc ccttcttacg aggatttgaa
    14041 gaacgatcat agaggtagag aacctcagtc ggctgcatat aagccttaac ccctgtcgga
    14101 accaagacaa tctctcctgg cgcaacaact gtacgcacag caacctttaa gtcgtaacca
    14161 gccgcatgcg ctgtctcacg cttgggcaat aaattttcat ctgtaaaact cgaaaccaat
    14221 tcaaaaccac gaattttcat aattttctct tttctattat catttattct agattattct
    14281 atcttattta ttcggaaaaa gcacgaaaaa aagagcacac aattcaaatc gcttagggct
    14341 gctggattcc tcccctgacc cgcttcacgc agaactgttg ctccactatt tattatatca
    14401 cattcctatt cattttaaaa gcaaaattat tttttccgtc tatttctaaa aaaatcctgc
    14461 atgatagctg cgcattcatc ttccaaaatt cctatttcaa cctccacacg atgattgaga
    14521 cgctcatctg tcaagatatt gtacaaactc ccagcagcgc caaatttctg gtttttagcc
    14581 ccatagacca catttggaat gcgggcaagc ccaatcgctc cactacacat gacacaaggt
    14641 tcaatggtca caaaaagtgt gcaatccagc aagcgccagc tctcctcact caagttcgca
    14701 tcctctatag ccataatttc cgcatgcata accgctcgct gtaattcctc acgcgcatta
    14761 tgcccacgac caatgatttc cccatctttg acaatcacac aaccaattgg aatttcatcg
    14821 tgttcaagag caatctcagc ctctctcaaa gcctccctca taaagacttc tttttcttca
    14881 agcgtataat acatctcttt tctcttttcc tacttatcga ttttattatt atatcatgaa
    14941 tcccaacaca aaaaaagcca ccgaatgcgg tgactctata gggagattat tatgaaaaag
    15001 aaaagtttag gatatttgtt acaacaagtt aggaggtctt cttgtaaccg tctatagtat
    15061 acccgaccta tcttaaacaa atcttaaaaa tctcttagga ccaaacactt tctaaaatat
    15121 ttgtttgttc acgaccagga cctactgaga aagtagaaat acgaacgcca accaattcac
    15181 tcacacgacg aacatagtta cgcgcattct caggaagatc ttccaaattg cgaactccgg
    15241 taatatcttc tgaccaacct ggcaactctt catagatagg cttgcaacgt ttcaattgct
    15301 caagactagc tggatagtag tcaatacgtt gaccgtcaag atcataggcc acacagattt
    15361 tcacagtatc caaaccgctc aaaacatcaa tagagttcaa agaaaggtta gtaataccag
    15421 aaacacgacg gctatgacgc atcacaactg agtcaaacca acctacacga cgtggacgac
    15481 cagttgttgt accatactca tgacccactt cacggatacg ttctcccact tcatcaaaca
    15541 actcagttgg gaaaggacca tctcctacac gactcgtata agctttacat acacctacaa
    15601 ccttgtcaat cttgcttgga ccgacaccag aaccaattgt cacaccacca gctacagggt
    15661 ttgatgacgt aacaaatgga taagtacctt ggtcgatatc tagcataaca ccttgtgcac
    15721 cttcaaaaag cacacgtttg ccattatcaa gcgcatcatt caagataaca gatgtatcta
    15781 tcacgtattt cttgatttgt tgaccatatt cgtaatattc ttcaaaaata tcatcgaaaa
    15841 caatcgcttt actgtcatac aatttttcaa aaagacgatt cttttcagca aggttacgtt
    15901 ctaaacgctc acggaaaata tctttatcta aaagatctgc aatacgaatt ccaacacgag
    15961 cagccttgtc catataagct ggaccaattc ccttaattgt cgtaccaatc ttattgtcgc
    16021 ccttagcttc ttcttgcaag cgatccaact cgatatgata aggcaaaata acatgcgcac
    16081 gatcagaaat acgcaagtta tcagttgtta caccttcctc atgaagatag ctcaactctt
    16141 ttacaagaga tttaggattt acaaccatac cattcccaat gacagatatt ttttcaggga
    16201 agaaaatccc agatggaatc aagtgcaact taaatttctt accgtcaatc acaatcgtgt
    16261 gaccagcatt atcaccacct tggtaacgtg caatcacttc tgcattcgct gaaaggaagt
    16321 ctgtaatctt ccctttacct tcatcacccc attgggtacc tacaacaaca actgaagtca
    16381 taatcttgtc tgagccctca ggctcttcct ttctcacata catggcagga ctctcacctg
    16441 caattatatc ttacaattta ttataataaa aaatcgtctt tttatcaaga agaaacaata
    16501 gaaagatttg ctatttccaa ctattaaaaa atgatttaga aaaattacta gctatttact
    16561 atcatctttc cataaaagag taaattagtt cggaaattta ctaaaattac ctcaacaaga
    16621 aataaaaccc cgattcatta ccaatttttc aagatacaaa cgataagcaa cacgataatg
    16681 gtaaacaata aaatccttac gacaaccaat gccatatctc actaaataat aaattaaaaa
    16741 tttaaaatga acatgttccc agtcaaaatt atcaccaaat gtaggaccat actcttcttc
    16801 aatactatca tagaaattag ccatctgctc ataaattttt tgtaacataa tcaaatactc
    16861 cttttctttt ttataaactt attctaacaa aaaattttac acattcacta tcaattcctg
    16921 aattgttaaa ataccagcct caacaagata aaaataggaa aagttgacag aatagaaaca
    16981 aatttgctac ctaaatttca aacgattaaa gttctaaaaa gaccgcctta aaacttttgg
    17041 gtaaatccta ttagaactat aatattttta tataggtatt atggttctga ttttctagta
    17101 taaaaaattc aaactagaat tcttcttaga aaaggccgtt ttaagtgcta tcactgttca
    17161 aaaatgaggg tcgctgaaac ttctatcgtc aagaagaatc atcaaattcc ttgtatcatc
    17221 aaccaaaaga ttgctcagaa gctaattaaa aagacttcta tgaccgacat tgatcatcag
    17281 ttgtctattt caacttcaac tgtcattcgc aagatcaatg attttcactt tgagcatgat
    17341 ttttcgcgtc ttcctgagat tatgtcctag gacgttgaaa cagtccgggg agtgactgtt
    17401 tcaatcggga gatggagatg agctttattg ctcaagactt tgataagctc aatatcataa
    17461 ctgttcttga gagcagaaca caagccatca tccgaaatcc catgaataca aggctatcaa
    17521 gcgatactga aagctcattc aacaagatag tcagaaactg agtgataaac gattttatcg
    17581 ccctactttt cgtatgcact tgactaataa agaaattcta gataaacttt tgagctattc
    17641 cgaagacttg aaacaccact ataatctcta tcagctcttg cttttccacc tctttttcag
    17701 actctgttta aaaccttcct caaagataaa gagaaaatcg tcaacgccct tcaattacct
    17761 tattccaacg ccaaactgga agccaccaat aatctcatca aacttatcaa gtacaatgcc
    17821 tttggtttta ggaactttga aaacttcaaa aaagaaagga cgaaatttgt cctttctaga
    17881 tcttcgcttt cttcaaccca ctacagttga caaagaaccg aaaaatgtct cgcctctaat
    17941 atagtcaatt gaaacaagaa caagacaaaa gagcctcata aaaggtattg caacttgcta
    18001 ataccttttt ggggttcttt ttgatatgaa cccatgtttt ctcaatagga ttgtactcag
    18061 gtgagtaggg aggaagaggt aaaagtttat gcccaaactc ttcacacaag agttctagct
    18121 tacccattct atggaatctt gcattgtcca taatatagta gattgaaact agaatagtac
    18181 acctctactt ctaaaacatt gttagaattc gattttactg tcctgatcga tttgtcctat
    18241 tcttatttca ttttactata acacgaaata gattattatt acataacaaa aaagaggtct
    18301 aaacctctta actaaattac tccgccagta ggactcgaac ctacgacatc atgattaaca
    18361 gtcatgcgct actaccaact gagctatggc ggatta
//
LOCUS       DBEJKC010000038        17280 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.038, whole genome shotgun sequence.
ACCESSION   DBEJKC010000038 DBEJKC010000000
VERSION     DBEJKC010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17280
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.038"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(96..1511)
                     /locus_tag="ACL3G6_001405"
     CDS             complement(96..1511)
                     /locus_tag="ACL3G6_001405"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGR0545916.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGSGTLNRY
                     KKMSFTWYKEVIESNGESLFK"
     gene            complement(1524..3362)
                     /locus_tag="ACL3G6_001406"
     CDS             complement(1524..3362)
                     /locus_tag="ACL3G6_001406"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGR0545917.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3380..4219)
                     /gene="licT"
                     /locus_tag="ACL3G6_001407"
     CDS             complement(3380..4219)
                     /gene="licT"
                     /locus_tag="ACL3G6_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HGR0545918.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(4519..6213)
                     /locus_tag="ACL3G6_001408"
                     /pseudo
     CDS             complement(4519..6213)
                     /locus_tag="ACL3G6_001408"
                     /inference="COORDINATES: protein motif:HMM:NF012403.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            complement(6316..7301)
                     /locus_tag="ACL3G6_001409"
                     /pseudo
     CDS             complement(6316..7301)
                     /locus_tag="ACL3G6_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397831.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
     gene            complement(7404..7547)
                     /locus_tag="ACL3G6_001410"
     CDS             complement(7404..7547)
                     /locus_tag="ACL3G6_001410"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545919.1"
                     /translation="MTGQRLNELEINGIRLTKFKNGEIGIEFIWIDTENPPSDAIGWV
                     AKK"
     gene            complement(7587..8342)
                     /locus_tag="ACL3G6_001411"
     CDS             complement(7587..8342)
                     /locus_tag="ACL3G6_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HGR0545920.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSLEDLY"
     gene            complement(8413..11064)
                     /locus_tag="ACL3G6_001412"
     CDS             complement(8413..11064)
                     /locus_tag="ACL3G6_001412"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HGR0545921.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VNLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIGKA
                     TANFDKFEFGVAGHILYNFIWDEFADWYVELTKEVLYSDNEEDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELDRLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(11076..12038)
                     /locus_tag="ACL3G6_001413"
     CDS             complement(11076..12038)
                     /locus_tag="ACL3G6_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HGR0545922.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDTNFAYRF
                     CHSLRNYSQHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKEYFNALTELYGNYNKLFLKLNHNTLVDIKSKLESLKLKHSRYYISK
                     ISKYDLKYNPGNYTMSPLAAFAEIEEIYIELSKIGLVKIVNKSN"
     gene            complement(12040..12597)
                     /locus_tag="ACL3G6_001414"
     CDS             complement(12040..12597)
                     /locus_tag="ACL3G6_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR0545923.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAACALIDLAFKELGLHKIELTCFGYNLQSQRVSEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEE"
     gene            complement(12584..13162)
                     /locus_tag="ACL3G6_001415"
                     /pseudo
     CDS             complement(12584..13162)
                     /locus_tag="ACL3G6_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813803.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
     gene            complement(13446..13841)
                     /locus_tag="ACL3G6_001416"
     CDS             complement(13446..13841)
                     /locus_tag="ACL3G6_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGR0545924.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(13937..14191)
                     /locus_tag="ACL3G6_001417"
     CDS             complement(13937..14191)
                     /locus_tag="ACL3G6_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HGR0545925.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(14201..15535)
                     /locus_tag="ACL3G6_001418"
     CDS             complement(14201..15535)
                     /locus_tag="ACL3G6_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HGR0545926.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(15535..15768)
                     /locus_tag="ACL3G6_001419"
     CDS             complement(15535..15768)
                     /locus_tag="ACL3G6_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HGR0545927.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            15799..15951
                     /locus_tag="ACL3G6_001420"
     CDS             15799..15951
                     /locus_tag="ACL3G6_001420"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545928.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDRTDEVSSKHRFEVVDRTDEVS
                     NIYTAR"
     gene            complement(16216..16398)
                     /locus_tag="ACL3G6_001421"
     CDS             complement(16216..16398)
                     /locus_tag="ACL3G6_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545929.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(16400..17179)
                     /locus_tag="ACL3G6_001422"
     CDS             complement(16400..17179)
                     /locus_tag="ACL3G6_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545930.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQDPTTLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGIGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
BASE COUNT         5282 a         3759 c         2827 g         5412 t
ORIGIN      
        1 aagaagttta gaatttaatg tcttccaaac ttctttattc catatttaat gaaatgccac
       61 cttaaccgtg ataatagcta gtcatcaata aaaaactatt tgaataagga ttctccattt
      121 gattcaatca cttctttata ccaagtaaaa gacattttct tatatcgatt taatgtacca
      181 cttccatcat cgtttcgatc aacataaatg agaccgtacc ttttagaaag ttgtgcagtg
      241 gacatagaaa cacagtcaat acatccccaa gacgtatagc ccataatttc aacaccatcc
      301 tgtagagctt cagcaacttg caataaatgt tctttcatat actgaattct ataatcatct
      361 tggactgtta agttattaaa ttcatctttt attagttgat ctttagcacc taatccgttt
      421 tccactataa ataatggaat ttgataacgg tcataatatc tatttaaaat tatacgtagt
      481 ccaattggat caatttgcca tccccactca gaagactcta aataaggatt tactaaacca
      541 ccaataatat tcccttctcc tgaattatac tgtgttggaa gagcagattg agtcacactc
      601 atgtaatagc taaaggataa aaaatctaca gtataatttt ttaataactc tgcatcttca
      661 gctgcaaact ctatgttaat gtcattttcc ttaaaatatc tttttgcata attcggataa
      721 taacctctaa catgcacatc tgaaaataga taatttagat tctcatactc atgagtcgcc
      781 catacatctt ttggatttgg agtcattgga taagctggca tagctaatac catacacccc
      841 accttaaact ctgaattaat ctcacgagca atttttgtaa ccaaactcga ggcgactaat
      901 tcatgatgta tagcttgata taattcttgt ttcgaaagat tctccttagg tatatctatt
      961 cctccactag taaacggtaa ttccaaaaca gagtttactt cgttaaatgt aagccaatat
     1021 ttaactttat ctttatacct ttctaaaact gttcgagcaa atttttcata aaaatgaatc
     1081 attctcctat caatccatcc atgatatttt cttgctaaat ataatggagt ctcatagtgt
     1141 gaaagagtta caagtggttc tatcccgtga gcatgtagtt catcaaacaa ttcatcataa
     1201 tatttcaacc cagcttcgtt aggttcttcc tcatctcctt ttggaaaaat tctactccat
     1261 gcaatagaag tacgaaaaac attaaagccc atttcagaaa acaaggatat atcttcctta
     1321 tatttatgat aaaaatcaat acctatcaat tttaagttat cttctgtagg attttctgtt
     1381 gcttctccta atccaccttt gggtaacaca tcctgaactg ataagccctt accatcttca
     1441 ttatatgctc cctctacttg attagctgca acagctccac cccaaagaaa atcatctgga
     1501 aaaatggtca taactttcct ccattataat attaccagta attccttaga atgctcgatt
     1561 gtctgattat taggtaatac taatacatct agaaaatcat tggtattcgt tacaattact
     1621 ggtgtaactg tttcgtagcc tttagtcttg attaaattca agtccatttc aaaaatcaac
     1681 tgatttttga aaactctgtc tccttcttct acatgactaa taaaaccttg accttttagc
     1741 tcaacagtat ctaatccaat atgaattagt aactcaacac cctcatcact cttcaatcca
     1801 attgcgtgct tagtcggaaa aatatttgta attttcccat caaatggtgc ataaacctta
     1861 ccttcacttg gaataatcgc tactccgtct ccaattagtt tatctgaaaa tgttttatcc
     1921 tggacatcgc ttaacggaat gatttctcct gatataggag aaaatatcat ttttttattt
     1981 gaaactccag ctttaacttc taaattgcta gaactctctt cttcatcgat tccaaatata
     2041 taagctaata caaaggtaat aacaaccgaa ataaccgcca caattaaagc atttacaata
     2101 tttgatggca catcagaata aataaattga ggcaacgcta tcaaagatgg gacagcaaat
     2161 agatacgctt taacactagt aagacctgca aataatcccg ctaatccacc accaatcata
     2221 gctgcataaa gcggtttttt atattttaaa gtcacaccat ataatgcagg ttcggtaatc
     2281 cctgcaagta aggctgagaa acctgctgca aaagcaattt gttttgtatt attattttta
     2341 ctctttaatg caacagccat cgaagcagcc ccttgagcta agtttgaccc taacattgct
     2401 ggaagaatta atacgtctgg agtagcaata gatgccgcca aaaaaatagg tgcaaaagcc
     2461 caatgcattc cagtcataac aataaatggc ataatagcac caagaatagc taatgtaagc
     2521 catccagcta caccatacat ttgcccaact agatttgata atccttcacc aacaattact
     2581 ccaataggcc cgactacaac taaggcaata cagcttgata ctaataatac tagcgtaggt
     2641 tgcaaaaaac tcttagtaac agctggtgtt aatttagcaa tcattttttc aatatatttc
     2701 atcaaccaaa ccataataag aattggaacg actgacgaac cataactagc tggtgtcaca
     2761 ggtacaccaa ataaactaag aggattccct gattgcacca tttgaacaaa atttggatgg
     2821 agaagtacac ctgctacaga catagctaat gtagatgtta cttttaattt ttgtgatgca
     2881 gaataagcta ataacagcgg taagaaataa tatggagcat ccccaaaaaa tgtcaaaaaa
     2941 gcaatagtct gagaatctga ttgcaatata ccaagcattg gtaaaataat taccaagact
     3001 ttcagcatac ctccccctaa cattgctgga atgattggag tcatggaacc agcgatatac
     3061 tcaatgattc tttctaaaat attccctttg tgcccttgaa caactgaatc ggattcaaaa
     3121 ttgccaagtt taacgaattc tttataataa ttagctacat cattaccaag tataatttga
     3181 tattgtccat tctttttcat aatacctatt acacctggta tcttcttcac atcatcatca
     3241 ttgactaaat tttcatcttt taattctaat cttaaacgtg ttacacaatg ggtaactcta
     3301 ttgacatttt tttcacctcc aattacatcg aggatttttt gtaccgtatc tttataactc
     3361 atggtattct cctattctat taatctaaat tttttgttaa gcgacgaata tgagccatca
     3421 aataaactaa ttcactagaa gtcagcaaat aattgtactc cgtttgtata aacattgcca
     3481 cctgttcacc acattcatat tctctaggat atttattttt cattaatgct aacaagtctt
     3541 catcatcatc gtcacaataa gttgtatttt caaccaagcg atgggcaaat aattttatat
     3601 gagttatgaa tctataataa tcaatagaat cttggttaaa ctcagtacaa tagaaatctt
     3661 gaatgatttt ctcaattccc ataattattt cagtgatttt atacgactct tgaaaattat
     3721 tttctaaatt agcattaaca aaatgtagcg ctatgaatgc agcttcgtca attggaagtt
     3781 caatacctaa ctcttttttt attatttgta aagccctttt cccaagttca aattcttctt
     3841 tataatattt cgatatttcc cagcgtaggg gattcgaaat aataatccct tctttataac
     3901 gttctatgct cgaagaaata tgatccgtta aattaatata gataatttca tcaaaattat
     3961 tacccaatgt tattttacct aggttaatta ttttttcggt gatgtacacc aactccaaag
     4021 gaacgttaat aaacatctct gtaaaacggg tcatattatc tctatttttg agaaaaaaac
     4081 ttttctcaat atcaattgga tttactttat ctccagtttt tcttccaaaa gctattcccc
     4141 ttccaaaaag aagaatatcg atatcttttt tactttgcgc aattacggca ttgtggttta
     4201 gtattcgttt tatgatcata aaatttccct tttaaaataa aaggaaccta cttaaaaaca
     4261 tcaagaaact tcttctgatg tgattaaata ggttcctgct cacttgtatt agtgataaca
     4321 tccttttatt tcaattttta atggtgacat gaagcttaaa taattaataa ctctgtaacc
     4381 gtttttattt tatgatattt caatctattt gtcaagtact tataaaaatt tttttatttt
     4441 gtgtgattcg aatgtgataa tggcaacagt ctcactaaag aaatgaaaat catacataga
     4501 aatttttaaa aattttctct atcgtaaacc tgccactagt tcagaaacta tactagctga
     4561 ttccaaacgt aatatggtca tctcatctac cttccctaat aatggcattg caccatacca
     4621 aacaatagtc ttattcacca aaagaatagg cgttactatt tttgattgag taaaagacac
     4681 tttaattttc tggctcttca actggtctag ccatgcttta tttgcaaccg tctctggtat
     4741 acatatctca atttgactaa tcctaaattc ttttagaaaa ttcatcagtt ttgtctggtg
     4801 cacataaggt aaaataagca gacattcctg tctttcccct gctaagtcct ctctcaacac
     4861 cttctcatat ctactatcaa cataaacgaa ttgtttctcc tcaccctcaa tggcacgata
     4921 atccatcttt cgataagcta cttgtcgttt ctgaaacatc ttttctaaat aaggaacatg
     4981 aatatccaca taatcgaaaa tacgcaccaa agacttatcc ttgtagtttc tatgaatcca
     5041 acctgcatac tgaatcaaat tatttttcca agaaaagggt gctgccaaga taagcgtgtc
     5101 caactgaggt aagtcaaaac cttcgccaat gtattttcca gtagacaaca aaacaaaccc
     5161 tttatctaac tgttctaacg tctccagtaa actcgttctc tctcggactt tggtttttcc
     5221 gctaataatg taacagtcat caacctcttt ctctttcaat aatttttcaa agacatctat
     5281 ctgttgaatt cgattaacta aaaccaagat attccgtcct tctgccactt gggctagaat
     5341 atccttgaga atcatctgat tcctcactga gtcagtagca atccaatcac taagctgtat
     5401 aaaattactt gctttggtct tttcaatttc caaatgacca aaagaagtga atcttaattg
     5461 caattgccgt ttaaaatccg tttccctctt atcagcagta tggagtatct caccaattct
     5521 ctgaaaaaca ataggctcat gaccattctt acgctcaggc gtagccgtca aaccgtaaag
     5581 atacttccct ctaaactgag caacaacttt ttcaaacatc aaggcagaga catgatgaca
     5641 ctcatccaca atcatcatct catactcatc caaaagactt tgactatttt ccaacttaaa
     5701 tagagattga atcataacga catcaaccag tttactcagc catttcttag tcccaccgta
     5761 ctgcccaaca tagccgatta ccttttcacg acctgatgcc gtataacgga tagcctcctc
     5821 ctcttcgaaa gtcaaaaagc agtttaagcg atctagccat tggtctaaga gttgcttatt
     5881 atggactaga ataattgttt ttgttttccg ttcagagata agagcagcac ctaaaacggt
     5941 cttcccaaaa ccagtctccg catgaagtaa accattttct ttagaagtca tatctgacag
     6001 ggctaactct tgctcaaaag tgagttctcc cttaaattcc acgctaatag acctttgtac
     6061 ctttctccta tcttccacag atacctgctt aaatttatct tgcaatggat acagcaaacc
     6121 tcttggcaac cataaataat gatcggattc tccaaataaa tacattctct caggaatttg
     6181 ataggttggc tgtcgcatag cctgctttaa atatagtaaa atgaaataat aacaggacaa
     6241 atcgatcagg aaagtcaaat cgatttctaa caatgtttta gaagcagagg tgtactattc
     6301 tagtttcaat ctactataaa attcgggatt agaaaaggaa gccatatttt tcaagaaaaa
     6361 agtgccttgg atgtcacaga cgatttttca agttggatca tattggataa aacgaccttc
     6421 aactccttat ccaattcttg cttgcctaac tcctcttgga ttaacagtgc cactttagca
     6481 gttgaaatcc tctgaatttc ttgtagatac ctccattggt cttcataagg ctgaaactgt
     6541 tcatccacaa agaccgttcg cccttgatgg taagcttctc cttgaaaagg caaggcaatc
     6601 aaatttccaa atcccccctt aggaaggaca tcctgatttg gaaacatgcg atcaaaagaa
     6661 tcaaaggaca gttgcatact ttcctgcatt gccaattcta atagtttctt tccaaacagg
     6721 cgagcctttc gactcagaat cgcttcctca aagaagaacc aaatatggag tccgtaaccc
     6781 gaacgagaaa tctctaaatg ggcttccatc tggcgttccc tggctattct tcgaatggtt
     6841 aaaccagctt ctttccaatc tccttcatcc aaatccagta ccaaaaaata acagctatca
     6901 tctaagtgca taggaaagat accgatagct gcctccccac gaaaatgaga tttcaaaacg
     6961 gaatccgtca atgtctggaa actccgtttt tcaggtagca actgcttcca accataatca
     7021 taggaaggaa aatactgaat tttcccttga tcattgataa aactcttagc ataaacatca
     7081 taacggccag caaacacaga ggtaaacaat tgtaattttt cttgcgtcgt caagcgacta
     7141 ctttgaagtt ggaacatctc ctcgaactga gagcgttcca taacaaactg actcttgtct
     7201 ttaagacgtt tacacaagaa aaactcacta tccccatcaa aagaagaaaa gacatcaagt
     7261 acttctacca caattccatc caaagacaca aaaacagcca taagagtcac ctccttgatt
     7321 cctataggct gattataaca agaatagctg aaattgtaca cgaaaataaa atcccttatt
     7381 tgttacaata cctttgaaaa cttttatttc tttgctaccc agccgatggc atcgcttggg
     7441 ggattttcgg tatcaatcca gataaattca ataccgattt ccccattttt aaatttagtt
     7501 aaacgaatac cgttgatttc cagttcattg agtcgttgac ctgtcaagac ttctcgttct
     7561 ttcaactgga aaagttaagg ggggaactaa tacaaatctt ctaagcttct atattcaatg
     7621 atttcatttt tgataatatt ctttttaaac tcaaaatgtt ttaaaggatt atcgattaac
     7681 actaactttg gaatatcatc tagatttgtg accaaggata aaataaaatc cgattgaaac
     7741 tccttgactt tttcaaattc ttttgcagtt aaacgcacac gccccttaga ttttcggata
     7801 ccttttactt cggcaaggta agaatactct tggacatcta cctgaaagtc atatccatca
     7861 ccataaagac gggcatcggt taactgtcca ccttggaatt tttcttcttt atcaaaatga
     7921 aggataaaat aattctcagc ctccattccc gtttcctgta gacgtttgaa tttagttcga
     7981 actattggtt tttcaacgat ggttatgcct gttttcttcc cttcactggc aagtaacatt
     8041 ttaactattt cagcataact atgaacatct tcatttccaa acatcatatc aattaaatct
     8101 ttacgaaaac gataaacttc agctttctgc caccaacctt ttcgattatt gtcaaaataa
     8161 ggatcaaata aatccattct attttttaca actccagttg tttcagcaat tcccagagaa
     8221 accacataac gataaaactc cgacttgcta gagcattgaa attcttttat aaaaagcttg
     8281 tcaaacttgg caagaccgta gccaattaaa tttaacaatt cataatgagg gtgtttggac
     8341 atcactttct ccatcaatag atattgattt cattatacca aaaaaacacg gctcatcacc
     8401 gtgtttctgt gtttatttaa cgagtttctt catctcatca atacgtgcta cggtcgcatc
     8461 atacttggct tggtagtcag cttgtttgtc gcgttctttt tggacgactt ctggtttggc
     8521 gttggctacg aagcgttcgt tagagagttt cttaccaacc atgtccagtt ctttttgcca
     8581 tttagcgagt tctttgtcga gacgatctag ttcttcttca acattgagga gatcggccag
     8641 tggcaggtag atttctgctc ctgtgatgac acttgacata gccagttcag gtgcagggat
     8701 ggttgatgcg atttccaaat gttctggatt tgtaaagcgt ttgatgtagt tgacattgct
     8761 gttaaagaag gcttccaagt cactatcgct agtcttaaca aggattgtaa taggtttgct
     8821 tggtgctaca tttacttccg cacgcgcatt acgaacggca cggatcaagt ctttgagact
     8881 ttctacacca gtgtgagccg caaggtcttc aaaggctaga ttaacagttg ggtatgcagc
     8941 tgtcacgata gaaccttctg agatttgtcc aaagatttcc tctgtcacga atggcatgat
     9001 tgggtgaagg agacgaagga tcttgtccag agtgtaaagg agaacagatc gagtaattac
     9061 cttatcttct tcattatcgc tataaaggac ttccttggtc aactcaacat accagtccgc
     9121 aaattcatcc cagatgaagt tgtagaggat gtggccagca acaccaaact caaacttatc
     9181 aaagttagca gttgcttttc caatcgtttc attgaggttg tggagaatcc agcggtccgt
     9241 cacattacca gcctcacctg ttgcaacttt tgtgacattg tcatgcgcca catccagcgt
     9301 caaacctcca ttgttcatga ggatatagcg agaaatgttc caaatcttgt taataaagtt
     9361 ccatgaagca tccattttct cataagagaa acgcacgtct tgtcctggcg cagaaccgtt
     9421 tgaaaggaac catcgaaggg catcggcacc gtatttctcg ataacatcca ttgggtcaat
     9481 cccgttaccg agagacttag acatcttgcg tccttgctcg tcacgaataa gaccgtggat
     9541 aaggacgttt tggaatggtt gacggcctgt gaattccaat gactggaaga tcatacgaga
     9601 cacccagaag aagatgatgt cgtaacctgt taccaaggtt gaagttggga aataacgttt
     9661 aaagtcttct gagtcgactt caggccagcc catggttgaa aatggccaga gggcagaact
     9721 gaaccaagta tccaagacgt cttcgtcctg agtccatccg tcaccttctg gagcttcttc
     9781 gccgacatac atttcaccat cagcattgta ccaggcaggg atttggtgac cccaccaaag
     9841 ctgacgagag ataacccagt cgtggacatt ttccatccat tgaaggaagg tatcgttgaa
     9901 acgaggtggg tagaattcga ccttgtcctc tgtgtcttgg ttggcaatgg cgttcttagc
     9961 caattggtcc atcttgacga accattgagt agacaagcgt ggctcaacta cgacacctgt
    10021 acgttctgag tgaccaacac tgtggacacg tttttcgatt ttgacaaggg caccgatttc
    10081 ttccaactta gcaacgactg ccttacgagc ttcaaaacga tccatgcctg aaaattcaaa
    10141 ggcaagctca ttcatagttc cgtcgtcgtt catgacgttg acttgtggca agttatgacg
    10201 ttggccaacc aagaagtcat ttggatcgtg ggcaggtgtg attttcacga caccagtacc
    10261 aaactcagga tctgcgtgct catctccaac gattgggatg agtttattag cgattggaag
    10321 gatgacgttt ttaccaatca agtccttgta gcgcgggtct tctggattaa ccgcaaccgc
    10381 aacgtcccca aacatagtct caggacgagt tgtagcaact tcaagggcgc gtgaaccatc
    10441 ttccagcatg taattcatgt ggtagaaggc accttccaca tccttgtgaa tcacctcaat
    10501 atcagaaagg gctgtgcgag ctgctgggtc ccagttgatg ataaactcac cacggtagat
    10561 ccagcctttc ttgtaaaggt tcacaaagac cttacgaaca gcttttgaca aaccttcgtc
    10621 aagagtgaaa cgctcacgag aatagtctac agagagcccc atcttgcccc attgttcctt
    10681 gatggtagtg gcatattcgt ctttccattc ccagactttc gtcaagaaag actcacgacc
    10741 aaggtcatag cgggaaatgc cctcaccacg caagcgctcc tcaaccttag cctgagtggc
    10801 aatccctgcg tggtccatcc caggaagcca aagggtatca aaaccttgca tgcgtttttg
    10861 acggatgata atatcttgca aagttgtatc ccaagcgtga ccaaggtgaa gtttacctgt
    10921 aacgtttggt ggtggaataa cgattgaata aggcttagcc ttttgatcgc ctgaaggctt
    10981 gaaaacatcg gcatcaagcc atttttggta acgaccagcc tcaacctcgg ctggattgta
    11041 tttagatgaa agttctttag acatgtgtgt tctccttaat tacttttatt gacaatttta
    11101 accaaaccaa tttttgaaag ttcaatataa atctcttcaa tttcagcaaa tgctgcaagt
    11161 ggtgacatag tataatttcc aggattatat ttaagatcat acttgcttat ctttgaaata
    11221 taatacctag agtgtttcaa ttttaatgat tccaactttg atttaatatc tactaatgta
    11281 ttatggttta actttaaaaa caacttatta taattaccat agagctctgt aagagcatta
    11341 aagtattctt tcactagagc tatagcgtca atcttagatg tttcttggtt tagttttatc
    11401 aactcccctt tcaatttttt ccatttaaag ttggaattta aaagataatc taaatcaata
    11461 tagaaatcta ttataacagt ctcatcatct gggctaacag cttttacctc atttattggt
    11521 aagtcagtat gttgcgaata atttctcaaa gaatggcaaa atcgataagc aaaattggta
    11581 tcatactgat agcttgcaaa accatgtata caatcaaact cctcactatc tttggaatat
    11641 ttttgtttaa tttggttttc gttaaaatcg acaaacaatt ttccactgga taataaatga
    11701 atcatgaaac gatttacatc tgcctcttca atttctaatt cctttgactc aagtttattt
    11761 ttaatactta aaaaatccga gacatctgaa ataaacaatt cgaacatatt cttgattttt
    11821 tgaaaattct tttgaatctc aaaaatttgg tccgatactg acattatttc cttggttggt
    11881 tcaatatcag agatgacaat acgtttttca ttgttgttaa tttctaaata agctaatcgc
    11941 tcgataatat cactatcatt taattcagca tactcaacat caatttggcg taactgcttc
    12001 tcagatagag agcttacttc ctcttttaca tcgctcatct tattcctccc actcgctctt
    12061 cagcaagcca tatatcagac tgtcacagcg gtttccttga acatcctttc ggtctcttat
    12121 gcgagcttcg agggtaaagc caagcttttc cgagactcgt tgactttgaa ggttatatcc
    12181 aaagcaagtt agttcaatct tgtgaagacc aagttcttta aaagctagat caatcaaggc
    12241 acacgctgct tctggaacat aacctcgccc ccaatagtct gggtgtaagg tatagccgat
    12301 ttccagcaca tcatcttcat ggcgatggtt gaaatcgaca gagccaacga tcttatccgt
    12361 tcctttgacg acaatcccgt agcctgctgg gagattttcc ttttgattac gctccggaag
    12421 aatgtgctcc agataataaa tctcatcttc caaggtcttg actggaggaa aacctgctgg
    12481 ataggcaacc tctggcaaac tagcatagtc aaagatatcc tcagcatccg ccacagtacg
    12541 gactcgtaaa acgagacgtt ctgtttcgat tttatctggc agctcagttc ttgccatcct
    12601 tcttcctcgc ttttttgatg aaactgccct tcatatctac acgcttgtcc agatagcgat
    12661 aaacgcgctg atatccatct cccatgaaat aggttggggc aaacagttga tttttaaaat
    12721 gtcccttttc atccaggagt tctggaacaa caagtcgctc aagaatcttg gcaaagatgt
    12781 ggcaaatacc gtcttcctca acaatcctat ctacccgaca atctaaaaca agtggacagg
    12841 cgtctaaaat aggagtctga gttcattcag aaatttcata atgcactccc aaacgttcca
    12901 atttctcctg atgactgata aaaccagcct gctccatcgc aagcatagaa gtttcatcag
    12961 aaatattcac agtaaatttt tgatactgtt tgatctgctc tgcggcattc tctcttgcaa
    13021 cgactccaat cacaacccaa tctcctagac tataagagga actacaggtc gtgatgttat
    13081 agccaaaatt ctaatcttga tatcctaaaa taaaaacagg aaaaccataa tatagtttac
    13141 ttgtgttaaa agattgcttc ataacaaccc cctttgacta agacgtaaaa gaaaagccct
    13201 gccatctaca tgacagggac gaatgtgttt atccgcggta ccacccaatt tcgggcagtt
    13261 gcccgcaact ctcgtcttta aagcaaaaag acacttttat ttcaattttt catccattag
    13321 caaccagttt tgacacattt gtggacttct cagcgccgcc actttctgta aaatgtggga
    13381 ttcaaaacac ctctaatggc tctattgtag caagattttt tcggaaatgc aaggctcaag
    13441 aaaaattact tgaacttgat gccattttct ttcaatttct tgatggtagc tgggccgatt
    13501 cctttcaagg caaggagttc tttttcagtc cagtttttga aatctgaagc agacttgatt
    13561 ccttcatcat agaaagtctt ggcacgatca agtggaagtc cacccaaatt tgctgcaaaa
    13621 tcttctacag aattagctac tttttgagct tgctctttgg tagcttctac tgcttgttca
    13681 acttttttag aaacagcctt accagctgcg cttgctgact gttctgcacg cttcacgact
    13741 ttttttgtct catctacaac cttagtcaca gtacttgaaa aggcacctgc gcgacggagg
    13801 ccatttcgta attgtttttt acgattgagt ttctttgaca tgataaaatc ctttcaataa
    13861 aaaatccctg ctctgacaag gatttaacat aaacattcta tcaagatttt agtgaaaaat
    13921 caagaatctt tctcgtttaa taatttcgct caccaaacaa gccttctggc aaatcatgga
    13981 atcccttgcc tgctttgaag ttttcaaact taccaagcaa gaactgataa gcatccaagc
    14041 gactctcgta gcgaatcatg gcatctttgg cacgctcgtc ctggtcttct tcgtaaactt
    14101 tttgactttc cttgtgcgcc atatcgttaa tcatgatttg ggtattgacc caagcttcaa
    14161 attccttcat aaattcttgt tcgtaactca ttttttctcc ttattctaat ccacgaaaat
    14221 agtccgtatc aatctcacgg tagggctgga tatcctgaac atactccaac actccttgga
    14281 attctccgtc ttcatcgtgt actgcagcat aggtgatgtg gacaaactta cctcgcgact
    14341 cagacttgaa ccacatttca tacttgtctt tgcttccctc acgaagcccc ttcatgatag
    14401 ttttgacctt gtccaagtac ttaggcggat ggcagagttc gacattgcgc ccgacttggg
    14461 acggcgtccg tttgaaaatc atctcatcag ctggcgtatt gtcattgtaa tactggaaaa
    14521 tatcttcttt attgacaaag gtaatctcca tagggagatg attgaggatg agattggcct
    14581 gctcgactga aagatagcca ttaccaaaag cctgttgact atggcggtcc agcacagctt
    14641 ccttttcctt aggggtaaag gtaatggtaa aatggccttc tggcgtatct atgacttgtt
    14701 gaacttgacc ttctgccgta tctagctgta caggctcctc tgcaatcttt tcctcaataa
    14761 agctctgtcg ttctggcacc catttctctg acggacggat gatggcatag ccataggcat
    14821 cgctctcctc cgcaatctga agccagtcat cctgagtaaa agactcaagg agaatcatga
    14881 ggaggatgga ctcttccttg aaaatcatac tttcaaactc tgtcgcaaaa gcttcaaaag
    14941 cttcctttac actgctaatt gacacttctg gtagtgactt ggctgtcgtt agagctgttt
    15001 gaaagagttc cctaatctga tcatccactc cccacataac tttgggaggt gaatcgtgtc
    15061 catagcgctc catgatagga aagaagagtt cttccttacg ttggtaatgg atgtcaaatt
    15121 gacccacaag tcccatctga cgcaccaaac ccttacgcat ctccgccagc atttcctcgt
    15181 cttccataga ctcataggta tctaacaatc tacgaatgcg aatcaaggcc gcacggagag
    15241 ccagattttc ttctttgaag acacgaactg ggtgacctgg atgctcagta tctgaaactt
    15301 cgacaccttt gatagcattt ttaaaaagat tggcatggac atcacagagt tccataacat
    15361 cttcaaaagt gacgcccgaa tccgagttca tcagctcgtg ctccataagg gaaatctcga
    15421 tggctgacac gcccgtaaag gtcgcatcaa agcgatcttg aaccgactca ggagaggcgc
    15481 cattgtgcaa ttctaacaaa atatcccgta ggatatgaat ccgttcatct gtcattagtc
    15541 taatccaatc acttcgtagc cattcgcttc cagtgtgcgt acaatcttgt ccataggagt
    15601 tcctgctagc ttagaaccct gtttaagtga tactttacga ccaactgtat tgcgcattaa
    15661 gggattggca aggggtttaa aacccaactc cactagaatt tccaagactt ctggatgctt
    15721 gtccaccact tctgcaacag gaattgacac atcgatgata ttgtccatga cgacctccat
    15781 tgtatgttct aatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggttgc
    15841 tcaaaacagt gttttgaggt tgtagataga actgacgaag tcagctcaaa acaccgtttt
    15901 gaggttgtgg atagaactga cgaagtcagt aacatatata ctgcaaggtg aagctgacgt
    15961 ggtttgaaga gattttcgaa gagtataaaa tgattttact gcttatatta taccatatgg
    16021 aaagagaata aaaaactagc agtggagttc ctgctagttc tctgcaactt ggattaccat
    16081 ctagataagt ttaaagaacc aatccaatat cttgtaaaac agcaattgaa ctgcaaaaga
    16141 aatgatcatc caaaagaatt tcacaatccc aataatcggt ttgataaaaa gaatagcaag
    16201 aagaccaaaa aaatttcatt ctctctcctc tggcttaatg agccaccgag ccgtatccat
    16261 tagcttatct gcaataaaaa gtttgcccag accaacaacg acatggtcag ctttctttat
    16321 cgttttcatc acttttacac cttgcacggt caaaaagtaa ttaccataaa ttttagcaaa
    16381 agctttgata ggattcatat tactctcctt tgatgatttc agcctctttt cggattgttt
    16441 caacatcttc ttgatattga acttcactat agttgactag cttggataat tctttctgca
    16501 agctttcccc cattggtttc atagttgcaa aggttaaacc acctgaaatg ataccaccca
    16561 agataggaat aaatttccct attcctttgg ccagccctcc cttggtaaga ttcacaccaa
    16621 atatttttaa gacttttttc aaaatagggt accaaagcgt ctttgttaaa gctttattag
    16681 gcactgtttt cattacctgt ttggcaattg ttataccacc agcacgtagc aaagcagcgg
    16741 ttccattcac ccctaacatt acgcctagat aaagcaagag ggtattttga gcatcttcac
    16801 tcaactcctc gcgtgaagcc caaagatcct cataaccata aatataacct aattcttgag
    16861 ccaatttcag agagaaagca taaaattgag ccacatcagc tggaatggta attgccatag
    16921 caagccctcc aggtaatcct gccaaaacag aagtcccact cgctaataat acattgtccc
    16981 gaatacaagc attagctaca cgatctaata tttcttgaga tagaagagtc gttgggtctt
    17041 gttccaataa ggtaggaata tcttttggat ccaattcttt ggaaaactta tccactaaaa
    17101 atttcgaacg atcaacctta acaacaggta gtttcaccac ttgttgcaat acttgcatag
    17161 ctaagtcttg ttcagccata tacaaactcc ttatttcttt tttgcacctt atcatattat
    17221 atttcctaca aaaaaagcat tttctaatta gataacatta aaaaatacag aacccctttt
//
LOCUS       DBEJKC010000039        17033 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.039, whole genome shotgun sequence.
ACCESSION   DBEJKC010000039 DBEJKC010000000
VERSION     DBEJKC010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17033
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.039"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(32..262)
                     /locus_tag="ACL3G6_001423"
     CDS             complement(32..262)
                     /locus_tag="ACL3G6_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545931.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(280..921)
                     /locus_tag="ACL3G6_001424"
     CDS             complement(280..921)
                     /locus_tag="ACL3G6_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0545932.1"
                     /translation="MKLLKNLGWILLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(933..1667)
                     /locus_tag="ACL3G6_001425"
     CDS             complement(933..1667)
                     /locus_tag="ACL3G6_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HGR0545933.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(1670..1867)
                     /locus_tag="ACL3G6_001426"
     CDS             complement(1670..1867)
                     /locus_tag="ACL3G6_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545934.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            complement(1867..2073)
                     /locus_tag="ACL3G6_001427"
     CDS             complement(1867..2073)
                     /locus_tag="ACL3G6_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0545935.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(2083..2550)
                     /locus_tag="ACL3G6_001428"
     CDS             complement(2083..2550)
                     /locus_tag="ACL3G6_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545936.1"
                     /translation="MIDKVVRNLLLTFFFCKMTKIINFLTTIIVKKKKMCYNEFKLRN
                     RKQKGVIMWVLVFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRLLQEMIGK
                     EPIITGVYIGPDNWEVVDVDEEWVKLRSVDKKGKEKFKLQRIEDIQTVEFDGE"
     gene            complement(2550..2741)
                     /locus_tag="ACL3G6_001429"
     CDS             complement(2550..2741)
                     /locus_tag="ACL3G6_001429"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545937.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDRTDEVSSKHGFEVVDETDEVS
                     NYTYGKVKLTWFEEILEEY"
     gene            complement(2738..4027)
                     /gene="hisS"
                     /locus_tag="ACL3G6_001430"
     CDS             complement(2738..4027)
                     /gene="hisS"
                     /locus_tag="ACL3G6_001430"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HGR0545938.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(4105..5352)
                     /locus_tag="ACL3G6_001431"
     CDS             complement(4105..5352)
                     /locus_tag="ACL3G6_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HGR0545939.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTFFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNAYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLDLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(5543..6394)
                     /gene="rgg"
                     /locus_tag="ACL3G6_001432"
     CDS             complement(5543..6394)
                     /gene="rgg"
                     /locus_tag="ACL3G6_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HGR0545940.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELLV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            6518..6859
                     /locus_tag="ACL3G6_001433"
     CDS             6518..6859
                     /locus_tag="ACL3G6_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGR0545941.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIEDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            6923..7087
                     /locus_tag="ACL3G6_001434"
     CDS             6923..7087
                     /locus_tag="ACL3G6_001434"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545942.1"
                     /translation="MKIKGQTRKLAAGCSKHCFEVMDRTDEVSSKYCFEVVDRTDEVS
                     NHTYGKATLT"
     gene            complement(7113..8816)
                     /gene="ilvD"
                     /locus_tag="ACL3G6_001435"
     CDS             complement(7113..8816)
                     /gene="ilvD"
                     /locus_tag="ACL3G6_001435"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HGR0545943.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIIDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(9049..9981)
                     /locus_tag="ACL3G6_001436"
     CDS             complement(9049..9981)
                     /locus_tag="ACL3G6_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HGR0545944.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     NFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPEAVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(9978..10835)
                     /locus_tag="ACL3G6_001437"
     CDS             complement(9978..10835)
                     /locus_tag="ACL3G6_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGR0545945.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(10839..12185)
                     /locus_tag="ACL3G6_001438"
     CDS             complement(10839..12185)
                     /locus_tag="ACL3G6_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR0545946.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(12198..12482)
                     /locus_tag="ACL3G6_001439"
     CDS             complement(12198..12482)
                     /locus_tag="ACL3G6_001439"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0545947.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(12486..14516)
                     /locus_tag="ACL3G6_001440"
     CDS             complement(12486..14516)
                     /locus_tag="ACL3G6_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR0545948.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            14707..15714
                     /locus_tag="ACL3G6_001441"
     CDS             14707..15714
                     /locus_tag="ACL3G6_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGR0545949.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGVFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            15717..15917
                     /locus_tag="ACL3G6_001442"
     CDS             15717..15917
                     /locus_tag="ACL3G6_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR0545950.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            16069..16251
                     /gene="rpmF"
                     /locus_tag="ACL3G6_001443"
     CDS             16069..16251
                     /gene="rpmF"
                     /locus_tag="ACL3G6_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HGR0545951.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            16267..16416
                     /gene="rpmG"
                     /locus_tag="ACL3G6_001444"
     CDS             16267..16416
                     /gene="rpmG"
                     /locus_tag="ACL3G6_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR0545952.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(16896..>17033)
                     /locus_tag="ACL3G6_001445"
     CDS             complement(16896..>17033)
                     /locus_tag="ACL3G6_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545953.1"
                     /translation="ESGSMATGWFTVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWV
                     G"
BASE COUNT         5516 a         3587 c         2914 g         5016 t
ORIGIN      
        1 acaaaaatcc gatgaacttc accggactct tttattttga atttttgcct gctttacgct
       61 tttcagcgat ttcggctgcc tttcgaggca agacaatttc cgttatgtaa gccgtcccaa
      121 aacgcagtac acctgcaata ggagcaaaga caactgctag atagttatag aagaaatcgc
      181 ctttgaaggc ataagctagc gctccaatga tgaaaaatag aacgactgcc tgaatcactg
      241 ctaataaaat tactcgtttc atgtgacctc ctgactctat tatagcatga gaatcatcaa
      301 aaagccgact aaattattca aagcgtgaag agaaatactg tagaccagac cttttctgct
      361 aatgtaagcc aaacccaaac taaaaccaag gctaaaatag acaaaaaatt gttgcacatc
      421 acctggaaaa tgaatcaagg caaatagaag actagatacc agaagaaaaa tcagggttcg
      481 tttactattg tcctgcttag gaaagagata gcgtgctaac atccctctaa aaacaatctc
      541 ttccgtcaaa ggagcaaaaa taaccacagc aaagaatgag aaaagtggtt gagacaaggt
      601 caagtctgtc gctatttgct gatttactga aggatcatct ggcaagaaga attgaacgac
      661 cagagataag aaccaaacca aggcaggaag ccaaataaat cggttaaagc cgctcttctc
      721 aatataaaca ggagctttct gataccattt gtaaatgccg tacacatata ctccagccaa
      781 gaccacatag agtagagtaa cagcataggg tgaagcgcct aaagcaagcg acgcagtcgc
      841 gagcccctga ataaagccat agataaagaa aaaggataga agggctagaa gaatccagcc
      901 aaggttttta agtaatttca tagataactc ctttatttga aataacgttt taccataggt
      961 aactgcatca cattgatata aacatggatg gctcctacaa gcaagaaagc tagtaactga
     1021 atctctcctg tcaagaaaga aatgataata agaaaaatat ataaggctgg taagacatat
     1081 tggtgtaatt ggaataaaat tcgaaaactc tgttccaaat tagcctgacg ctccccttca
     1141 tcataagaat ttatatagtt caagacatcc tttggtgtag cgaaaaattc caaatcaaac
     1201 tgacgaacaa tcgcaatggt tttaaaaaga gatttttgag cgactaagaa taccacaaag
     1261 agtaagaaag aaaggaaaaa tgtttgaggg tttgtatgca atataatcac ctcacttaat
     1321 gaaataaaaa tagccaatgg aatcgctaca cctgtaatat taaaagcaat ggttccaaac
     1381 tcaagattcc gatacatttg cacataatag gtttcattca gatcgtcatc catttcctct
     1441 tgatacaagg aatgaaattt tctgcttttc tttaagaaat tgaaagtcaa aaacatacta
     1501 atgaaaccta tcagtaaaca aatagctgat atccatggca tcaaggcttt tacatctaaa
     1561 ataatttcgt gggattcgac acgtgcctta aacatcccta caaacatgcc caagaacccc
     1621 cccaagacaa tagacatcaa aaataacaat ctacgtttct ttttcatatt cattctcctt
     1681 tttcacttgc tagatttttg gatttctttt caatccattc agttactggg atgagagcaa
     1741 agtagaccca aacaaattgg tcgctttgat agggattaaa ccagcttagg tccatcccaa
     1801 tcagtagaaa tacgctgact aataaagcta tgaccactac ataataaatc actttatact
     1861 tgttcatcac tcgtcctcct ccaaacgaaa taccgattcg actgtttcgt tgaaaatttg
     1921 agatattttc agggcaatga taatggatgg ggtgtactca tcccgttcta gtaggctaat
     1981 ggtctgtctg gaaacccctg ccagtttggc taggtcggtt tgattgagac catcgcgagc
     2041 tcgaagctct tttagacgat tttttagttg catgttacac acctactctc cgtcaaattc
     2101 aacggtttgg atatcttcaa tacgttgcaa cttgaatttt tctttcccct ttttatcaac
     2161 actacgtagt ttgacccatt cctcgtcaac atccacaact tcccagttat ctggcccaat
     2221 atacactccc gttataattg gttcctttcc aatcatttct tgcaataatc tcgacatttc
     2281 tgcgtttcct ttctcttttc gctcaagttt tttgatttta ttctctagtt tcttgatttt
     2341 tttagaatta ttagaataaa agaaaatcat aaatagtata aatactagta cccacattat
     2401 aactcctttc tgcttcctat ttcttaactt gaattcattg taacacatct ttttcttttt
     2461 gacaattata gttgtcaaaa agtttatgat ttttgtcatt ttgcaaaaga aaaaggtcag
     2521 gagtaagttc ctgaccactt tatctatcat taatactctt ctaaaatctc ttcaaaccac
     2581 gtcagcttca ccttgccgta ggtatagtta ctgacttcgt cagtttcatc tacaacctca
     2641 aaaccatgtt ttgagctgac ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag
     2701 caacctgcgg ctagcttcct agtttgctct ttgattttca ttgagtataa aatcctagtt
     2761 tttcaaagat ttctgagaag ttttggctga ttgtctcaag tgacacttgc acttcttctc
     2821 gggtttggtt gttcttgacc gtcacttgtc cgctttcgac ttcgctctct cctagggtga
     2881 tgagggtctt agccgcaaag acatctgctg acttgaactg agctttgagc ttacggttga
     2941 ggtaatcacg ctctgctttg aaaccttgtt ggcgaagagc ttggactagt tctagggctt
     3001 tgacatttgc tccatcaccc aagactgcga tatagacatc tagggcgttt tcgataggga
     3061 gggccacgcc ttgtttttca aggatgagaa gcaggcgctc tacaccaagc ccaaaaccaa
     3121 atccagcagt ttcagggcct ccaaagtaag caaccaaacc atcgtagcga ccacccgcac
     3181 agactgtcaa gtcattgccc tcaatctctg tgataaactc gaaaatggtg tggttgtagt
     3241 agtccagacc acgcaccata ttggtatcga tgatgtaatc tactccaaga ttttccaaca
     3301 tctgacgcac agcatcaaaa tgagtttggc tttcttcatc aagaaagtcc aagatagacg
     3361 gcgcattctc tactgccacc ttgtcttctt tttccttaga gtccaagaca cgaagaggat
     3421 tttcctccaa gcgacgttgg ctatccttag acaaggtctc cttgagcggt gtcaaatagt
     3481 caatcaaggc ttggcggtag gctgcacggc tctcaggatt tccaagagtg ttgaggtgca
     3541 atttgacacc ttgaataccg atttccttca aaaaatgggc tgccataacg attgtttcca
     3601 catcggtagc tggattgcta gagccaaaac actcaacacc aatctggtgg aattggcgca
     3661 agcgccctgc ctgtggacgc tcataacgga acataggtcc catgtagtag aacttgcttg
     3721 gcttttgcac ttctggggcg aagagtttat tttccacata ggaacggaca acgggcgcag
     3781 ttccttctgg acggagggta atatggcggt cacccttgtc atagaaatcg tacatttcct
     3841 tggttacgat atccgttgta tctccgacag agcggctgat aacctcgtaa tgctcgaaaa
     3901 taggcgtacg cacttctgcg tagttgtagc gcttgaaaat ctcacgggca aagccctcaa
     3961 cgtactgcca cttagcagac tcagcaggta aaatatcctg cgttcctttt ggtttttgta
     4021 atttcatagg gaatcctctt taaacttaat agtcttattt taccataaat agagggatta
     4081 aaacagtgag aaaaaaatta ggatttagat atcatttttg agattaagaa ttgtcaaaaa
     4141 aatagctagc aaggaaagac caacaaatag catccaagtc aactgtatat tccatacggc
     4201 tactagtgaa aaacaagctg ttcccacagg tatggataag gtaaacaata gatctaaaaa
     4261 attactagta cgagctagaa cctctggagc tagatttttc atgagcatgg cactaatctt
     4321 tggttgaact ttaccagaca catacagagt aaagaagaga aatagcaaac caagcacgac
     4381 ttgattgaat aaattagcca aaccaactag actaagtcct acagtcgccc acatcatcaa
     4441 tctaggcaag gactgcttcc caaaataagc attgcccgta aggctactga tgatgattgc
     4501 tactaaaaca cagaattgat tgataaatag tgcctctgta taagaaaaat tcaagagaga
     4561 atggctcaaa aagaagatat tataaattcc acccaaagcg ccacccaagg aattaataag
     4621 caagacagca aagagcataa aaccaaagtt tttctgccca cttttaagaa aaacgagacg
     4681 taaatttcgg taaattgtta ggaactggtc tttgatagaa agcttctcat tttttaagtt
     4741 ttcaccatca gcagatgaca ttgacaggct caatttgctt tttcctaaaa agaggatagt
     4801 ggctgatact aggaaaaagc aggcattgat tcccgcaacg agagaaaaat tgttgaccga
     4861 tagagctaag agccagactc cgaaagcttg accaccaata gctgaaatat aggtgatgaa
     4921 ctgtgaaaaa gaataagcct ccatcagatc atcttcagct actttttcct taataagagg
     4981 catacgcagg ccacctgcaa aatcactgat gatatcacta atgacattga tcaaacacag
     5041 gctagaaaag gcaaagagac tagcttgctg aacaactagg gctgctagaa aaaatagaac
     5101 cgcctgaaac aaaccgctat agaccatcca tttgaccttg tccctcgtgt aatctgcccg
     5161 aatccctgca aaaactgtaa agaaggtcgg aagaatcatg acaatattcg ccatagcaac
     5221 agcaaaagat gcttgtgaca aggtcgatgc atagacgata aagaccaggt tgaaaatcga
     5281 agcaccaaaa gcattgaaga agcgtgataa agtcaaaatt ctataagctg gatttctaaa
     5341 caatagtttc atagataatc tccctccttg ttctaagttc tacatcaaga atagctttag
     5401 tatagcactt atgaatttgc gaaacgattc ttttgaatat atgcaacaaa caaaatgagc
     5461 aaaaaaacga tagaactttt gtaatgacct gagagagggt aacagttcta tcgcttcaaa
     5521 ttttttcttg gtttgcagat actcaacatt cggtcgtatt tctatagtat tcggcagatt
     5581 tattacagcc aagcatctca aaaatacgga cagcatcctc catctttttc tggccttcct
     5641 tgactctacc ttgcttgcta tcaaggagac cttctgccca cagataaaca attcggaaat
     5701 aggtctcatt ttccttgtag aaatgctctt cgataacacg tttaaaataa taggcattgg
     5761 taaattcttc acactcaata ctagctaaaa agccattcaa tagtatagta tgaaaaaggt
     5821 ttcgattgcc agacatttcc attagaaaat cagatttacg taccatttct cgtacatatc
     5881 tagtaaaaag agaaacagat aaaaatggag aactgactga aaataaattg agttcataga
     5941 ttccccagat ctcggtagaa aacaaataat catgaaggac ttttccttcc tctgctgtta
     6001 actctaccct ttcatctatg ctcttcatat aagacttgat aataatggca tttagaatat
     6061 gtttctgttt gttgtgagaa tgggcatgct tttgatactc cctgcgatat aagtcctcaa
     6121 gaggtgctat attctttggt tccaagacat ctgtaatttc ttttctcaac tcagaatctg
     6181 tatcatactg gaaacctctc gccagaaaga ggatctcctc cacactggca gatatatttt
     6241 ccagagcaaa tagaaacttt tccaccaaaa gctcactctg acctgtttca aaacgggaca
     6301 acatagacgg cgaaaattgt cctccggttg cttgtctcag tgagatattt cttgactctc
     6361 gtaattgtct aaagactttt ccaatctgct ccatagactt ccccttgatt ccgtattttc
     6421 ttcattttat catatttttc agaaaattca tcaaaaactt gccaaattgt cagaattatg
     6481 agaaaataga ggatatttat cacgtggagg gactgctatg agagacgata tcaaaatcaa
     6541 tgaccgtgct ttggccttgc aagaccaaat tatcgaaaaa ctagagaaag tttttgatac
     6601 agatgtggaa ttggatgttt acaatctagg tctgatttat gaaatcaatc tggatgaaac
     6661 ggggctctgc aagattgtca tgaccttcac cgatactgcc tgtgattgcg ccgaaagcct
     6721 gcctattgaa atcgtggcag gtctgaaaca aatcgagggt atcgaagata tcaaggttga
     6781 agttacctgg tcgcctgctt ggaaaatcac acgaatcagt cgctatggcc gtattgccct
     6841 tggactacca cctcgttaag caggccaatc acttttaaag atgaaaaaag caagccgaaa
     6901 atggcttgct ttttgatact caatgaaaat caaagggcaa actagaaaac tagccgcagg
     6961 ttgctcaaaa cactgttttg aagttatgga tagaactgac gaagtcagct caaaatactg
     7021 ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat acctacggca aggcgacgtt
     7081 gacgtgattt gaagagattt tcgagtatga gtttattttt tacctgactt gtccatattc
     7141 cagaagtctg tcacggctcc gcgtgaagca gatgatacga tgtgggcata tttaccgagg
     7201 acaccacggc tgtaaagtgg tggcaaggtt gtttctgcct tgcgtttttc aagttcttct
     7261 tcggatacgg ccatggaaat ttctttggta tcttggtcaa ccgtaacgat atcgccggta
     7321 cggagatagg caattggtcc accatcctga gcttcaggag cgatatgtcc aacaaccaga
     7381 ccataagtac caccagagaa acgtccgtcc gtcaagaggg ccaccttatc tccctgacct
     7441 ttaccaacaa tcattgaaga aagtgacagc atctcaggca taccaggacc acctttaggt
     7501 ccaacaaaac gaacaacgac tacatcgcca tcaatgattt catctgtcag gacggcctga
     7561 atcgcatctt cttctgagtc aaagacctta gctggcccaa cgtgacgacg cactttaaca
     7621 cctgatacct tggcaactgc accgtcagga gcaaggttcc cgttcaagat gataagcgga
     7681 ccatccgcac gttttggatt ttcaagtggc atgataactt tttggcctgg agtcaagtct
     7741 gcaaagtcag ccaagttttc agctacagtc ttaccagtac atgtgatgcg atctccgtga
     7801 aggaaaccat ttgccaacaa gtacttcata accgcaggga caccaccgac ttcgtagagg
     7861 tcttggaaga catactgacc agatggtttc aagtcggcca agtgaggcac acgttcttga
     7921 atcgtattga agtcctcaag tgacaagtca acatttgcgg catgggcaat ggcgagcaag
     7981 tgaagagtgg cgtttgtaga accaccgaga gccatcgtta cagtaatagc atcttcaaag
     8041 gcttcacgag tcaagatatc tgatggtttg agaccaagtt ccaacatctt aacaacagca
     8101 cgtcctgctg cttcgatatc ttctttctta tcagctgatt cagctgggtg agaggatgac
     8161 cctggcaaac tcatccctag aacttcgata gcagttgcca tggtattagc agtatacata
     8221 ccaccacaac caccagggcc agggcaggca ttacattcaa gacgtttcac gtcctcagct
     8281 gtcatgtcac cgtggttcca ttttccgata ccttcaaaga cagaaaccaa gtcgatatct
     8341 ttaccatcaa gatttcccgg tgcaatagtt ccaccatagg cgaaaatagc tgggatatcc
     8401 atattagcaa tagcaatcat agatccaggc atgttcttgt cacagccacc gatagcgacg
     8461 aaggcatcca cgttgtgacc actcatagcc gcctcgatgg agtccgcgat gatgtcacga
     8521 gatgttagag agaaacgcat accaggcgtt cccatagcga tcccgtccgc tacggtaatg
     8581 gttccaaact gtacaggcca agcgcctgca gatttgacac cttctttagc cagtttcccg
     8641 aaatcatgca agtgaatgtt acatggtgta ttttccgccc aagtcgaaat cactcccaca
     8701 atcgatgttt caaagtcctt atctgtcata ccagtcgcac gaagcatagc acggttaggt
     8761 gatttaacca tgctgtcata aatgctactg cggtgacgtt tatctaattc agtcatctta
     8821 tccctcccat ttcagttttt actattatag cacaatttaa aggcaatgaa cagaataaaa
     8881 ttcttgaatt ttcagaaaat tctatacgca tgtgaaatat ttaaaattaa aaacaacaaa
     8941 gcggattagt gcactttctg atgaccagaa tatgcttttt aatccgcttt ctttaaataa
     9001 cgtactgtaa tttttacaga aattctttca gataagtgta tttaacatct atcttgcatt
     9061 ataaatttct agaaccttct cttttatatt cgattcactc aaaccatact cattaagaag
     9121 ataatccatt ttccctactt gaccgaatct ttcttgaaca cccatccgat gaatttttgt
     9181 tattccatca tcagagaata attcacataa agcactgcca attccaccta tctgattgtg
     9241 gttttctaca gtaaatatag tttttccact taacattgtt tttatctgtt ctggtatcgg
     9301 tttgattcta aataaatcta tcacacctac tgaataacct aatttagaca gttcatctgc
     9361 aactcgaata cttggagcaa ccattatgcc agaagcaacg attacaagat cttcaccatg
     9421 tcttaactca atgtagccct tagaaaaatc ttctccacct tgatatacag cctctggagc
     9481 ttttctaatt gttcgaatat attttagtcc ttttaagtct aatgtctgat tcaatatttc
     9541 acgaaattgg atatcatcag ttgcttcaaa aatgattgat ttaggaatta aacgtaacaa
     9601 tccaatttct tcaaatggca tatgtgtccc accattcatt tctgcagtta ctcctgcatc
     9661 tgatccaatc acagtggcat ccaattgtgc gtatccaaga gaaataaata attgatcaaa
     9721 tactcttcgt gaagcaaaag gaccaaatgt atgaagataa ggtctaaacc cctgaataga
     9781 caagcctgct gcaaggccga ccatttctgc ttccataatc ccaacattca cataacggtc
     9841 tccaaagttc ttttcaagat tattagtagc catcgaactt gacaaatcgg cttctaagac
     9901 tactatatca gaataacttt gattagcctc taaaaggaag tctctatata catgccgtaa
     9961 ttctttcgta cttctcatca ttctgtttcc tccaattcct gacttaatct ttctacaact
    10021 gaagttaaca tttgtttctc ctctacagta gggcgaagat gatgattgga tttcatttct
    10081 tccagctctt gaaccccttg acctttaata gtatctaata caatgcactt aggtgatgaa
    10141 ttatttgact gttttaattg gacaatccct tcataaattt ctctaatatc tgaacccttg
    10201 accctaatgg attcaaatcc aaatgctgaa aatttttcta cgaaatcacc tggattacaa
    10261 atatcctttg taaaaccatc taattgtttt ttgttatcat caacaaatac aattaagttg
    10321 gataactgtt gatgagaagc aaactgtata gcctcccaac attgtccctc atttaactca
    10381 ccatctccaa caatagcata agtataaaag ggactctttc ttattctctg accatatgca
    10441 agtccagttg caacactaat tccttgtcct aaagagcccg ttgtcatatc tatgcctggc
    10501 gttagatttc tatcaggatg agacggtaat ttggttccat ttgtatttaa agaatataag
    10561 aattctttgt caaagaaacc attcaaatag agtgtactgt atagagctgg tcctccatga
    10621 ccttttgata atatgaaata atctctatct cgtgctgcaa atatttctgg agtcattggc
    10681 attatttcac cataaagcac tgctaaaact tctacgatag acagacttcc tccgtaatgt
    10741 ccgaatccaa gatgattcaa tgttctaaga gtatttaatc ggatgttagt cgcaaatttt
    10801 cttaacccat cttctctatt tttacttaaa atcatccctt attcctcctt tgcagatggc
    10861 tttttaataa aggatactcc aaacataact gctagaataa gaacaagacc aatcacaata
    10921 cctgcttgtg agccaaattg atttaacatt cctaaaataa ttcctgatag accaaaatct
    10981 gcatctgaga aagttgatcc ttggaaacca agtcctccca aaactggcat taaaaagact
    11041 ggaagaaaac tgattaaaat accttgtaaa aatgctccaa tagtggcgcc acgaacacca
    11101 ccagatgcat tcccaatgac acctgcagtc gctccacaga agaaatgagg cacaacacct
    11161 ggtaagataa caaccgttcc tgaagcaatc ataattgcca tacttactaa accaccaaca
    11221 aaactagaga taaatccaat tagaactgca ttgggtgcat aagtataaac aatcggacaa
    11281 tccaaagcag gttttgaatt aggtacaaga cgctctgaaa tacctttaaa ggctggaaca
    11341 atttcgccca aaataaggcg aacacctgct aaaataacaa atacccctgc tgcaaattga
    11401 cctgctaatt gtaaagcata aactagacca cttgtaccac tactgatttc tttttctata
    11461 tattctgacc ctgcaaagat agctacaata atgtaaataa ctgccataga taaagtgata
    11521 ctaacagtac tatcacgtaa aaaagctaaa ctctttggaa atttaatgtc ctctgttgat
    11581 tttgatttgt caccgataag gctaccagta aaaccactca accaatatcc caaagaactg
    11641 aaatgaccta aagccacctt gtcatttcca gttaattgaa ccatatattt ttgcacaaat
    11701 gctggggaaa tactcataat aataccgagt gctaatcctc ctagtaagat gagaggcaag
    11761 ctagtaaagc cagcaactga taaaatgacc gcaatcatac atgccatata tagagtgtgg
    11821 tgccctgtta aaaaaatata tttaaatcga gtaaaacgag cgattaagat attgaacacc
    11881 atgcctgcaa acataatcat tgcagtagct gagccatatg ttgttaaagc tacagctaca
    11941 attgcttcat tattcggcac aacgccagat aaatgaaaag catgctcaaa catggtacca
    12001 aatggattta aagaattttg tacaattcct gcaccaccag atacaactaa gaaaccaaca
    12061 aaggtcttaa ttccaccttt aataatatca ggtaatttct tcttctgaag aactaatcct
    12121 aaaattgcaa ttaaagctac taaaatagct ggtgtactaa caatatccaa tatgaacttc
    12181 atcatgacgc tagcctccta tataagtcct ttttcttcac aaagtttagt aattaattct
    12241 cgtagttcat ccatatcaat aatactattt aagatacgaa catctccaag atgactagct
    12301 gaatcagcta gatcacgacc aacaatccaa atatcagctg catttggatc tgctccacct
    12361 aaatcataat gttcaacttc tacatccgaa acattcaaat cactcaatac agattcaata
    12421 ttcatctgta ccataaaact tgaacctaat cctgaaccac aagctgtacc aatttttaac
    12481 attatctaat cctcctgttt aattatcatt ttaatgtcat catagttttt tgatgatatt
    12541 aaagtttgaa catgattttt atctcttaaa attgttgtta aatgtgacaa agcctttaaa
    12601 tgactctcat tatcaatggc tgcaatacaa atcaacaatc ttacctcttg ttctggatta
    12661 tccaataaat aaatcggttc ttccaaaact aacattgaca ttcctatttc attcacacct
    12721 tcatctggcc gagcgtgagg aattgctact cccttcccta aattaataaa aggtccaaac
    12781 tcttctactt tttgaatcat tgcctcaggg tagttctcag ttatcttatc ttgatccaaa
    12841 agcggtttag ctgctaaacg aatcgcctcc ttccatccta atttttgcga actaacctga
    12901 taggtttctt tggtaataag ttgttctagc actggtacaa tttcctttct atcatttttt
    12961 tggtaaagat aattctttaa cgccaatctt aattccaatt cttgtgtaat aattccatat
    13021 cttttgacaa tattcaggat ttgttcaatc tcaaaatctc catactctaa attcggaaaa
    13081 tcttttaaca ctagttctac tagttgtatt gcttgctctt cagtcatcat aaccgaaact
    13141 agataatttg gcttttctgt ctccaccttt atggtagaaa aaaccatatc atagtcacta
    13201 ctagctttca cctgtaaatc atcaatcttt gaggttccta taaactcaat ttgaggaaat
    13261 aatgctaata gattctcttt taacatcaat gaagaactaa caccattagg acaaatgatt
    13321 gctgctttat agcatttttg aggcaaagta tctgctttct ttaaataacc tccgaaatgg
    13381 ataacaaaat atgctgtttc actatcaggt atgggattgt caatagcgtc catcaagggc
    13441 atcaaagaat ctttgactaa ttcaaataaa tcaggataat gttctttaac atgcaataca
    13501 tattcatttg aactaggtag gccgaacttt aatctatagt aagccggtat aaggtggcgg
    13561 cgaagatttt ctctcaatcc ttccctttgt ttaaaatgta acaaagaaat atcttccatt
    13621 ctacttataa tagcctctgt taattgatta aagtaaaccg gagcaacatc tacttcacct
    13681 tcaaagcaac ttgataataa aactgtgata tagcgataat catcctcaga aaacaccgta
    13741 tctataattc ccaaatcaac cactgtatcc aataaaatag tggttatatc ttgaataaca
    13801 ggagatacta atgtctctga aagacatact ctttcaacat ccctttgata cctacacaga
    13861 atgaatacta aaccgaaaag gcaaactttt aattgattaa caataggtac tagttgtagc
    13921 ttctcataat aatctttaac tacctgattt atcaaatcat aagttaatga atacccccaa
    13981 ctggataaaa cataatccaa accccaaatc cctatggagg attccagcaa ctcactaacc
    14041 atttgaaaag ctaagcggtg cttattccac tctgaaccgt gtaaagtata accttttgct
    14101 ctactgtacc ctagctccaa atcattatct aacataatct ttcttaatga ttgaatatca
    14161 gataaggttg tattcttact tactttcaaa aagtcttggt aatgattatt cgatataaaa
    14221 tctaatcggc aaaaagtgta aagatagatt aaagctaagc gagtcgactt tggtaaaacc
    14281 aattcatccg acttaataat atctgtcaaa gactgcttcg tacgatttga taaactatag
    14341 cgaccttgtt ttttatccag cactatccct ttattagcta gataaggcac taaataatct
    14401 attccttctt tgacttcctt tataggtaag ctcaccttaa cagataattc atataatgat
    14461 agctcacaat gatccatcaa agtcatcaaa ataactagtg ctctataatc aaacatttct
    14521 cttcctttct aactacaatt atagtgtaaa aattataaga ataaaagagt atttgagcac
    14581 aatataatct caccttttaa aagaaattat tgggctgaaa gtttttagtg attattttca
    14641 actttctatt gacttttaaa aacaaagtga tatcatttag atatcaaata atgggaggtc
    14701 attcttatga ctgaaaaact aatcaattca aaaccaaatg gtgtattcgc attgattctc
    14761 attgagttga caatcgtact tggtgtcttt atatttataa tgggtgttgg ttcggaaaac
    14821 atttttggaa ttattatcgg acctttacta atcgtaattg caggtctagc tcatgctggt
    14881 ttaaaagttg tcaaacctca ggaagctctg gttctgacac tctttggtaa ttatacaggt
    14941 accatcaaag aacctggttt ttactttgtc aatcccttca gcgtagcagt caaccctgca
    15001 aaccacactc gacttggaca aagtggtgat gttagcacaa aatctccttt tttaggagct
    15061 aaatcatcaa atgacaatga tgtaaatctt gaaattggca agaaacacat ttccctcaaa
    15121 gtcatgacct tgagcaattc tcgtcaaaaa atcaatgatt gcttaggaaa ccctgtagaa
    15181 atcggtatcg cggtaacttg gagagttgtc gataccgcta aggcagtctt caacgttgat
    15241 aactacaaag aatatctttc actgcaatgt gatagcgccc tccgtaatat tgtccgcatc
    15301 tatccttacg atgtgtctcc taatgtggat actacgggtg acgggcaagc agatgaaggt
    15361 agtctccgtg gctctagcga aattgttgct aaccgtattc gtgaagaaat ccaaagtcgt
    15421 gttgaggatg ctggcttgga aatccttgaa gcacgtatca cttacctagc ttatgctcca
    15481 gaaattgctg ccgttatgct tcaacgccaa caagcatctg ccattattga tgcacgtaag
    15541 atgattgtag atggtgctgt aggaatggtt gaaatggcac tagaacggct caatgaaggg
    15601 gaattggtag aacttgacga agaacgaaaa gctgccatgg tttcaaatct ccttgtcgtt
    15661 ctttgtggca atcatgatgc acaaccaatt gtcaacacag gaagtcttta ctaaagatgg
    15721 ctgaagctaa aaaaaagcag atcccccttc gactctcaac aaagttatac gctgcactcg
    15781 catcatgggc agaagacgac tttcgttcag tcaatggcca aatcgaatat ctcctcacag
    15841 agtgtgtcaa gcaacggaag aaagacggaa aatacgtatc agaaaccatt gacgaaccat
    15901 ttgagattga tatttaacac cttctcctgt ctgccgtgtc ggataggaga attttttcat
    15961 ctttttttgt caagtaactt tactttacaa aaaaaatgtg ttatcctagt atggttgatg
    16021 aaaatcagta gattgaatcg aatataaata cctaaaggag aaatcaaaat ggcagtacct
    16081 gcacgtcgca cttcaaaagc gaagaaaaac aaacgtcgta cacactacaa agtaacagct
    16141 ccatctgtaa actttgacga aactactgga gattactcac gttctcaccg tgtatcactt
    16201 aaaggatact acaaaggacg taaaatcgct aaagctgcat cagctgaata atagaaggga
    16261 gataccatgc gcgtaaatat tacacttgaa cacaaagaat ctggtgaacg cttgtacctt
    16321 acttctaaaa acaaacgtaa cactccagac cgccttcaat tgaagaaata ctcaccaaaa
    16381 cttcgcaaac acgttgtgtt tacagaagtg aagtaagcat tcaatacgaa tcaatacaga
    16441 agaaaaacgc ttgatcagcg ttttttcttt ttgttaattt cactatattg caagagaaat
    16501 cattcgaatg actacatttt ttgaaataag aatacggatt cggacgatta aaagtaagag
    16561 aaactcaaat gtaagttggg gttccttttt tgtatatttt tcaaataacg cctctacact
    16621 atttgtagca aattcaccaa ctacagttgc atcttagtta aaataagtta gaatatgtaa
    16681 gtgagtacca gatataccaa gacatcgtca ccatctaagg tatattcaaa atacaaaagt
    16741 tgaccaacta gatttctgaa tatccttata tatccattct taaaattggt ttaaatagcg
    16801 tagtctttta aactagtttt gagaatccaa aaaatcttcc tacatatgta agaagatttt
    16861 ttagttcaga atgattagat ttagctaatg gatacctatc ctacccactc accgttagca
    16921 ttgactcgat agccatcggg tgtagtcgtg tttactaata aatctcctga attataggta
    16981 tagtaccatt taccagaaac tgtaaaccaa ccagtagcca ttgaacctga ttc
//
LOCUS       DBEJKC010000040        16766 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.040, whole genome shotgun sequence.
ACCESSION   DBEJKC010000040 DBEJKC010000000
VERSION     DBEJKC010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 16766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16766
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.040"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            83..880
                     /locus_tag="ACL3G6_001446"
     CDS             83..880
                     /locus_tag="ACL3G6_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HGR0545954.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLIHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1028..2287
                     /locus_tag="ACL3G6_001447"
                     /pseudo
     CDS             1028..2287
                     /locus_tag="ACL3G6_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
     gene            2383..3657
                     /locus_tag="ACL3G6_001448"
     CDS             2383..3657
                     /locus_tag="ACL3G6_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HGR0545955.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="ACL3G6_001449"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="ACL3G6_001449"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HGR0545956.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="ACL3G6_001450"
     CDS             4786..5088
                     /locus_tag="ACL3G6_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGR0545957.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKHQS
                     VMADLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="ACL3G6_001451"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="ACL3G6_001451"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGR0545958.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /gene="xseA"
                     /locus_tag="ACL3G6_001452"
     CDS             5962..7302
                     /gene="xseA"
                     /locus_tag="ACL3G6_001452"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HGR0545959.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="ACL3G6_001453"
     CDS             7280..7492
                     /locus_tag="ACL3G6_001453"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HGR0545960.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="ACL3G6_001454"
     CDS             7489..8364
                     /locus_tag="ACL3G6_001454"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HGR0545961.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQVPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="ACL3G6_001455"
     CDS             8357..9172
                     /locus_tag="ACL3G6_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HGR0545962.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="ACL3G6_001456"
     CDS             9165..9596
                     /locus_tag="ACL3G6_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR0545963.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="ACL3G6_001457"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="ACL3G6_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HGR0545964.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDMTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="ACL3G6_001458"
     CDS             11272..12000
                     /locus_tag="ACL3G6_001458"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR0545965.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="ACL3G6_001459"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="ACL3G6_001459"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HGR0545966.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(13983..14180)
                     /locus_tag="ACL3G6_001460"
     CDS             complement(13983..14180)
                     /locus_tag="ACL3G6_001460"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545967.1"
                     /translation="MKIKEQTRKLAAGYSKHSFEVVDKTDEVSSKHGFEVVDETDEVS
                     NHTYGKATMTWFEEIFEEYKN"
     gene            14359..14835
                     /locus_tag="ACL3G6_001461"
     CDS             14359..14835
                     /locus_tag="ACL3G6_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0545968.1"
                     /translation="MVLDYFFDKNLVLCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAETTA"
     gene            14873..15178
                     /locus_tag="ACL3G6_001462"
     CDS             14873..15178
                     /locus_tag="ACL3G6_001462"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0545969.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            15226..16701
                     /locus_tag="ACL3G6_001463"
     CDS             15226..16701
                     /locus_tag="ACL3G6_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HGR0545970.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT         4977 a         3076 c         3874 g         4839 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg atacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat gatatggagg
     1021 tcaccttatg acttgtgatt ttaaatctga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatttt ttgtttttga
     1141 tgacacgtag gaaggtgccg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagctatcaa
     1441 agacaatacc aaacttgtct tgattgaaac cttgggtaac tccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaata ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggatggctt cagggaaatt ccctcaattt gttgacgagg gttcaagctg
     1741 ccacaatttg agctatactc gtgatgtggg tgcagtagcc tttattatag ttgttcgagt
     1801 tcaattgctt cgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa accctttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttattat gccttggctg agaaatactt gccaaaaggt gtcggttcaa tctttacctt
     2041 ccacgtcaaa ggtgacgagg aagaagcacg caaggtcatt gatcatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caatcactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaatc aaatccactt
     2221 gtctatcggt cttgaaaatg tagaagattt gattgaagac ttacgcttgg ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg ttttgactca ctgtttttga ttttccttca
     2341 tgcatgatat aatggttaca gaagtctaga aagaggaacg atatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gagagtcagt atgccgaact cttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaagcagga actggccttg
     2521 gcggagcaaa aggccatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattac agagtcagat ccaaaacttt gatacagaaa aagaattggc caagaaagag
     2641 gttgaacaga caagccatga ggctctcttg gctaaggaca aggaagtaca gctcttagaa
     2701 aatcagttgg ctaccttgcg tttggagcat gaaaatcaac tacaaaagac cctttctgac
     2761 ctagaaaaag aacgggatca ggttaaaaac caactacttt tgcaggaaaa ggaaaatgaa
     2821 ttatctttgg cttctgttaa gcaaaactac gaagcccagc tcaaggcagc tagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa cgaagcagac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat caacttaaaa aaagaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggtcgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaattactc tgggttattc cacgacgact
     3901 gaggatgcta gtggggaagt gatcgcagaa acccctgttt tgtctccctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta cccagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgctcgatt cacttttcgt gtaaaatgca gtaaagggac ttacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttg ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgat aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctggt gggaacttag gcccaggatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaaca ccaatcggtc
     4921 atggccgatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ctggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggagcctcaa gatgtcttta
     5521 tcgttgaggg cattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgta ttattcgtcg tatcaagcgt gatatggagg
     5641 aacgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat aaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaaatat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtctatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctaccccaa
     6361 ttttctaaga gaattggggt agtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acgaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatcctac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttgc tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgagacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattaactca tttgcaaaat
     6781 caggaaaaac ggatggcaac ggcagtccga aatgttctat ctaagaaaca agaggctttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccgttgta
     7201 gattcggttg agagtttgaa gaaaaaagat caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccttg caggttgcca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttggagat gattcataca gggagcttga ttcacgatga ccttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgccttattc ttagacccat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagattaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tggcagggca agttttggat atggagggcg aacaccagca cttgtctctg
     7981 gaagaacttc agactattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gtaagacacc tcaaaaggat ctgcaggcag aaaaatcaac ctatcctgcc
     8221 ttgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattggaag aaattgccca gcaggttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtgatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaaattcca gatgataccg aattaaaact
     8521 caagggggag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttggtac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gtcagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcac cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgcta agattcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggca ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agattcttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaaa
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgagatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattaccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgatacttt tgcagacaag atttttagtt gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgcac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgcctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgcaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gcacgtatcg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ctatgaatga catggaaagt gtcgaagagt
    10381 atgatcctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctga
    10501 tgcaggttga gaatcgtttg gacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgctaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaga
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cgttttagta
    10801 agggaaaatt cagtcgtgag ggaaatgaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagtatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattttt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacagtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatatgacag
    11221 aagcagccct gacgcaagcc agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tctcaaaacc
    11341 tgggatggtc agacccagtt gctctttcta ggtgatttga ttgacagagg tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatcgtcgca atggtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcggcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatctttgt tcacgcaggt
    11701 attgatttga ccttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacagga gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccac ggaaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggat
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatggag aaacttatat tttccacttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagcg cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 gggattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtgcgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggtt
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aagtacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggttttc gttgtggatt tcttggactt
    13141 ctccatatgg atgttatcca ggaacgttta gagcgtgagt tcaatattga cctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaattgt ctttgacttc tttgataaac ttaagtcttc aacacgtggt
    13501 tatgcaagct ttgactacga attgtcagaa tatcgcccat ctaagctggt gaaaatggat
    13561 atccttctca atggagataa ggtggatgct ctcagcttta tcgttcacaa ggactttgcc
    13621 tacgaacgtg ggaaactcat cgttgataaa ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaagttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataagaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcatcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaacctcaa aaccatgttt tgagctgact
    14101 tcgtcagtct tatctacaac ctcaaaactg tgttttgagt aacctgcggc tagcttccta
    14161 gtttgctctt tgattttcat tgagtattag aacagaaaaa tgcttggagt atttgtttgt
    14221 gtgtttattt ttatataaca aactataaac aaaacaaaaa tataaaaaag agacaaaaaa
    14281 gaacagaaag taattaacaa cgatttcata tagtgttata cttatggcat aaagttaatg
    14341 gaaagaaggg aaaaccttat ggtattagat tatttctttg acaaaaacct tgtgctttgc
    14401 ttagaagcgg ataatcaaga acaactcttt gatcaggtag caagcttgtt ggaagaacga
    14461 gaaattgtca ctcctactta tcgtgaagcc ttgatcacgc gtgaaaagtc atttccaact
    14521 ggtttagata tggaatttct aggaaaggac ttgccaaatg tagcgattcc tcacacagat
    14581 attgttcata atctagctga gaaagtggtg gttgttcgat tagaaaaacc agtaactttt
    14641 cacaatatga tagctcctga taaggaagta gaagtatcct tgctcttctt tatcatcaat
    14701 aactcaagtt caagtcaaac aaatattctg gctcagttga tggacttttt cacaggaaat
    14761 ggacatcttg aagacctatc aaaaatttcc gaaccagaaa aactttatgc ttacattgct
    14821 gaaacaaccg cttaatcttg tctattaaaa aataaaatcg gaggaaatct aaatgattaa
    14881 aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa gtgctctaga
    14941 agaagaactt tcaaaccgtg gttatgatgt tcactgtgat gcagtcatgg tgaaagatgt
    15001 aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa cagaccttgg
    15061 ttttgaacca ggtatcccag ttatcgaagc tggaccaatc ttattccgta tcccagcaat
    15121 gagcgctcca gtatttgaca atattgaagc agctattaaa gaacatggat taagctaatt
    15181 ctaatttgtt aacattcata taacataaaa aagggaggaa ctgttatgga tgcaatcttt
    15241 gacctaatcg gaaaggtttt caatcccatc ttagaaatgg gtggacctgt catcatgttg
    15301 atcattttga cagtattggc tttacttttt ggagtgaaat tctccaaagc gcttgaaggt
    15361 ggtatcaaac ttgccatcgc tcttacaggt atcggtgcta tcatcggtat gctaaatggt
    15421 gctttctcag catcacttgc aaaattcgtt gaaaacactg gtatccaatt gagtattaca
    15481 gacgttggtt gggcaccact cgcaacaatc acttggggtt ctgcttggac actatacttc
    15541 ttgctcatca tgttgattgt caacgtagtg atgcttgcta tgaagaaaac cgatacactt
    15601 gatgtcgata tctttgatat ctggcacttg tctatcacag gtctcttgat taaatggtat
    15661 gctgataaca atggtgtgag tcaaggggtt tcactcttta ttgctacagc agctatcgtc
    15721 cttgtcggtg tgttgaaaat tatcaactct gacttgatga aacctacatt tgatgacctt
    15781 cttaacgccc caagttcatc accaatgaca tcaactcaca tgaactacat gatgaaccca
    15841 gttatcatgg ttttggataa gatttttgaa aaattcttcc caggccttga taaatatgac
    15901 tttgatgctg ctaaattgaa caagaaaatc ggtttctggg gatctaaatt cttcatcggt
    15961 ttcatccttg gtatcgttat cggtattatg ggaactccac atccaattgc aggtgttgca
    16021 gatgcagata aatggcgtct tgttatcaaa ggatggttgt ctcttggttt gactgccggt
    16081 gtatctttgg aactcttctc acttatcggt tcatggttca tcgcagccgt agaaccacta
    16141 tcacaaggta ttacaaacgt tgctactaaa cgtcttcaag gacgtaaatt caatatcggt
    16201 cttgactggc cattcatcgc tggtcgtgct gaaatctggg cttgtgccaa cgtacttgca
    16261 ccaatcatgt tgattgaagc agtgcttctt tcaaaagttg gaaatggtat cttgccactt
    16321 gcaggtatca tcgctatggg tgttactcca gctctcttgg ttgtaactcg tggtaaattg
    16381 ctccgtatga ttatcttcgg aacactcttg ttgccactct tccttctttc aggtacactt
    16441 attgcaccat ttgcaacaga acttgctaaa ggtgtaggtg ccttcccaga aggtgtgagc
    16501 caaactcaat tgattactca ctctactctt gaaggaccaa tcgaaaaact tcttggttgg
    16561 acaattggta acactacaac tggtgatatc aaagcaatcc ttggtgcagt agtcttcctt
    16621 gtattctata tcggtatctt tgcttggtac agaaaacaaa tgatcaaacg taacgaagag
    16681 tacgcagcaa aagcaaaata atgcgctcct ataaaatata aacttaatga aaatcaaaga
    16741 gcaaactagg aagctagccg caggtt
//
LOCUS       DBEJKC010000041        15856 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.041, whole genome shotgun sequence.
ACCESSION   DBEJKC010000041 DBEJKC010000000
VERSION     DBEJKC010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 15856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15856
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.041"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(161..454)
                     /gene="rpmA"
                     /locus_tag="ACL3G6_001464"
     CDS             complement(161..454)
                     /gene="rpmA"
                     /locus_tag="ACL3G6_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HGR0545971.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(471..815)
                     /locus_tag="ACL3G6_001465"
     CDS             complement(471..815)
                     /locus_tag="ACL3G6_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HGR0545972.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(831..1145)
                     /gene="rplU"
                     /locus_tag="ACL3G6_001466"
     CDS             complement(831..1145)
                     /gene="rplU"
                     /locus_tag="ACL3G6_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HGR0545973.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQVVYVEKLNVEADQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(1181..1268)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(1363..1962)
                     /locus_tag="ACL3G6_001467"
     CDS             complement(1363..1962)
                     /locus_tag="ACL3G6_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HGR0545974.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGDVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            2432..2731
                     /locus_tag="ACL3G6_001468"
     CDS             2432..2731
                     /locus_tag="ACL3G6_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HGR0545975.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            2950..4027
                     /locus_tag="ACL3G6_001469"
                     /pseudo
     CDS             2950..4027
                     /locus_tag="ACL3G6_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(4343..5317)
                     /gene="pta"
                     /locus_tag="ACL3G6_001470"
     CDS             complement(4343..5317)
                     /gene="pta"
                     /locus_tag="ACL3G6_001470"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HGR0545976.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(5361..6257)
                     /locus_tag="ACL3G6_001471"
     CDS             complement(5361..6257)
                     /locus_tag="ACL3G6_001471"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR0545977.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(6254..7072)
                     /locus_tag="ACL3G6_001472"
     CDS             complement(6254..7072)
                     /locus_tag="ACL3G6_001472"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HGR0545978.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(7056..7727)
                     /locus_tag="ACL3G6_001473"
     CDS             complement(7056..7727)
                     /locus_tag="ACL3G6_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HGR0545979.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            7855..8424
                     /locus_tag="ACL3G6_001474"
     CDS             7855..8424
                     /locus_tag="ACL3G6_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HGR0545980.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8537..9496
                     /locus_tag="ACL3G6_001475"
     CDS             8537..9496
                     /locus_tag="ACL3G6_001475"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGR0545981.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            9506..10621
                     /locus_tag="ACL3G6_001476"
     CDS             9506..10621
                     /locus_tag="ACL3G6_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGR0545982.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            10626..10973
                     /locus_tag="ACL3G6_001477"
     CDS             10626..10973
                     /locus_tag="ACL3G6_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HGR0545983.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFSLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            10981..11196
                     /locus_tag="ACL3G6_001478"
     CDS             10981..11196
                     /locus_tag="ACL3G6_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGR0545984.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            11279..11920
                     /locus_tag="ACL3G6_001479"
     CDS             11279..11920
                     /locus_tag="ACL3G6_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HGR0545985.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            11938..12627
                     /locus_tag="ACL3G6_001480"
     CDS             11938..12627
                     /locus_tag="ACL3G6_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGR0545986.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYNLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(12624..13304)
                     /gene="radC"
                     /locus_tag="ACL3G6_001481"
     CDS             complement(12624..13304)
                     /gene="radC"
                     /locus_tag="ACL3G6_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HGR0545987.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(13347..15638)
                     /gene="pcrA"
                     /locus_tag="ACL3G6_001482"
     CDS             complement(13347..15638)
                     /gene="pcrA"
                     /locus_tag="ACL3G6_001482"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HGR0545988.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
BASE COUNT         4886 a         3391 c         2939 g         4640 t
ORIGIN      
        1 tttgtccttt ctcgagctta gctgacttca acccactaca gttgacaaag agcctaaaaa
       61 aacaggctct ccgaaaactc ggaaagcctt attttaagct gtttctagct tcctcacctt
      121 tatatttcaa ggttcgggat aaaaggttca atggaccttt ttatttagcg attgggtaaa
      181 cagaaacttg ttttttatcg cgtcctttac gttcaaagcg tactacgcct tcaactttag
      241 cgaacaaagt atcgtctcca ccacgaccaa cgtttacacc tggatagatg tgtgtaccac
      301 gttgacggta aaggattgat ccacctgtta cagtttgtcc gtcagctgct ttagctccaa
      361 gacgtttcgc ttgtgaatca cgtccgtttg atgtagaacc tccacctttt ttgtgggcga
      421 aaagttgcaa gttgttaaga gtcattttta acataatgtt ttcctccgtg ttagttttct
      481 gtgataactc tggtttggac gaactcagaa gagttctccg ataagtttgc catacctaag
      541 aaaaatgatt caaagaataa ctgggtcatt tctctctggt gtgaaggaag atcttttggt
      601 atttcaacca tcagatagcc accttcatct tcgtttaatt ctaggattgg ttcatagcct
      661 gcaaatttct caatagaatt gataaagtta atggcaagcg tagaaaccga tgcacacacg
      721 acatctaagc cgtattcgcc actctcggcg tgtccagtaa tttccgcact cctcagctcg
      781 ccatcttcgg ctctctcaaa gactgcctgt atcatgtgtt ctccttaaaa ttaagcgttg
      841 attgcgttga tgacaacttt tgtatatggt tgacggtgac cttgtttacg gtggctacct
      901 tttttaggtt tgtacttgta agtaaccact ttcttttgtt ttccttgttt ttcaacagtt
      961 ccaactacag tagctccagc aacaagtgga gttccgacaa cagtgttttc accaccaaca
     1021 agaacaactt cgttaaaagt aacttcttga tcagcttcaa cgttcaattt ttcaacgtaa
     1081 actacttgac caacttcaac tttaacttgt tttccgccag ttttgataat tgcgtatgtg
     1141 ctcattatgc acctcctatg atttttatgg gtttccccga ttttttgtga agactcgcct
     1201 agcatcgtgg gacgaaccac ttaaacttga ataatcaagc aacgatgttc gtgcggttgc
     1261 acaggatcgt gcatagtcaa ctcttcaagt atagcatatc tcctattttc ttacaagtaa
     1321 taacacctaa aatgaagctt tttcttttac ttttttctgc cactaggcaa aaagcatact
     1381 gagataaaaa atgctcatca taataggaac accaagaatg gtcttttcat gatagaaaat
     1441 cgtcaaatag gctgaaaaga catcgccaag gacaaaacta ctaagcaggc taacaaatat
     1501 gaacccttca cgcaaaaaag gagtgtgctt agttcggaaa taatctccaa aagctagcat
     1561 tgttcgtttg atattccctg tcataaaggc attattgtag gcaatacccg aaacctcacc
     1621 aaaagcagtt gtcaccagtc ccatacagaa ggccaagggc tgcactagat agatattatc
     1681 tacagtttgt ggcacaaaac caataattat tgataggatt gctaaaggaa tcaaggacag
     1741 aataggtttt ttcacaattc tcaatttttc cttataaatc gttaataaaa agactcccat
     1801 tataaacgtt attaaggtta aaagcttatc cctaacatcc gaaacattat tttgtattag
     1861 ctctaccgaa agaaagacaa catttccagc ttgtccagct acaagggtat tccctcgaac
     1921 aataaaagtg taagcatcca catatccagc acaaaatgtc aaaaaagtgc taacctttta
     1981 gactgacgtg atatttttct tataggtaat aacctcattt tccctcccat tgtattttct
     2041 cttagaaata ttgtaccatt tctttctaaa aaatcgtaga ctaccattta gattttacta
     2101 ttagcataaa aataataata gacaactatt tatccaaaaa tagatagagg taacatgttt
     2161 gcaaacaaag catacgaacc tttagtaaaa tcatttccat gaaactagaa tagagcccct
     2221 cttagcaaaa atcattattt taatttattt ctaatcactc cttgacataa ataactctca
     2281 ccaataaaag actatgtctt aaaaaaatgg tataataaaa tcaatacctg ggcttgatgg
     2341 ctatgctact aataacaatt aggagagaaa atcaggcact tgttaacaac aaggattatc
     2401 cccttgagat gaaaggaact ttagaaatct tatgatgaac atgcaaaaca tgatgcgtca
     2461 agcacaaaaa cttcaaaaac aaatggaaca aagccaagct gaacttgctg ctatgcaatt
     2521 tgttggcaaa tctgctcaag atcttgtcca agcgacctta actggcgata agaaagttgt
     2581 cagcattgat ttcaatccag ctgtcgttga cccagaggac cttgagactc tttctgatat
     2641 gaccgttcaa gccatcaact ctgctcttga acaaatcgat gaaactacta agaaaaaact
     2701 gggtgctttc gctgggaaat tgccattcta aaaacaagga gctagaacaa tacttgtcga
     2761 taacaaaggc taagaaaggt gcaaaaatta taaaaaacgc atagtatcaa gcaacctaaa
     2821 actttgggct ctataatatt tgtagtgggt aaatccacta tagatattat ggagcctatt
     2881 ttattgtaga aaaaaatccc ataagatcta taatgaaaag cgaccaaaca actcattaga
     2941 aagattcata tgggacaatt acattttatc acaaaattac tagacattaa agaccctaat
     3001 atccagattt tagacatcat caataaggat acacacaagg aaatcatcgc caaactggac
     3061 tacgacgccc catcttgccc tgagtgcgga agtcaaatga agaaatatga ctttcaaaaa
     3121 ccgtctaaga ttccttacct tgagacaact ggtatgccta ctagaatcct ccttagaaag
     3181 cgtcgattca agtgctatca ctgttcaaaa atgatggtcg ctgaaacttc tatcgtcaag
     3241 aagaatcacc aaatccctcg tatcatcaac caaaagattg ctcaaaagtt aattgaaaag
     3301 atttctatga ctgatattgc ccatcagctt tccatctcaa cttcaactgt tattcgtaag
     3361 ctcaatgatt ttcactttga gcatgatttt tcgcgtcttc ctgagattat gtcttgggac
     3421 gttgaaacag tccggggagt gactgtttca atcgggagat ggagatgagc tttattgctc
     3481 aggactttga taagctcaat atcataactg ttcttgagag cagaacacaa gccatcatcc
     3541 gaaatcccat gaatacaagg ctatcaagcg ctactggaaa ctcattcaac aggatagccg
     3601 taaactgagt gataagcgat tttatcgtcc tacttttcgt atgcatttaa ccaataaaga
     3661 gattttagac aagcttttga gctattcaca agacttgaaa catcactatc agctctatca
     3721 actcttgctg tttcactttc agaataagga accggagaaa tttttcggac tcattgagga
     3781 caatctaaag caggttcatc ctctttttca gactgtcttt aaaacctttc taaaggacaa
     3841 agagaaaatc gtcaacgccc ttcaactacc ctattcaaac gccaaattgg aagcgaccaa
     3901 taatctcatc aaacttatca agcgcaatgc ctttggtttt cggaactttg aaaacttcaa
     3961 aaaacggatt tttaccgctc tgaatatcaa aaaagaaagg acaaaatttg tcctttctcg
     4021 agcttagctt ttcttcaacc cactacagtt gacaaagagc cagaaaacgc ataatagcag
     4081 gtgtcaagac acttaatatt atgcgttttc tcatgaaaaa attctctttt catactcatt
     4141 taaaatcaaa aagggaaatt atcgttttac ggacatacat attacagatt tctataggtc
     4201 gtgtatagac aggatatcat cgcttggaag ttttcctttt tgacaccaat cagtaattta
     4261 gttctcagga attaatggca gtgcttttcg tacatagttt cataactaca gtatagcata
     4321 gtatatcgct ttatagtttt cactattgat gaactgcttg agctgctgtg atgagggtca
     4381 acttgtaaac atcatctgca ttacatccac gagaaagatc attaactggc ttgtttaaac
     4441 cttgcaaaac aggtcctaca gccgcaaagc cacccaggcg ttcagccatc ttgtaaccga
     4501 tatttccggc ctcgatacct gggaagatga agacatttgc ttgaccagct accgtacttc
     4561 caggagcttt cagagctgca gtttcaggaa caaaggctgc atcaaattgc aactcaccat
     4621 cgatttcaag gtcaggacgc aagtcgtgag caattttagt tgcttcaacg accttatcaa
     4681 cgctttcacc aaaccctgaa cctttagtag aatagctcaa catggcaatt ttaggttcga
     4741 tgccaaacat cttagctgtg attgctgagt tgatggcaat ttcagccaag gcttctgcat
     4801 ctggattgat gttaatggca cagtctccaa ataggtaacg ttccgtacca cgaaccatga
     4861 ggaaggctcc tgaagtacga gttacatttg gacgagtttt gatgatttgt agagctggac
     4921 gaactgttga agctgttgag tgaatcgctc ctgacaccat tccatcaacc aagcccaagt
     4981 aaaccaacat cacaccaaag tagttgacat cttcaaccaa aaccttgcgt acatcttctt
     5041 cagtcatttt gcccttgcga cgctccacca aggcagaaac catttcttca aattgaggat
     5101 aatgttgagg gtcgatgacc tcataaccat ccatgattcc ttcaatttca agataaattt
     5161 taattttttc aggatttcca agcaaaacag gaatcacttc tgtttctttt actaagcgtt
     5221 ttgttgcttg aagaatacga ggctcttccc cttcagggag aacgatacga gcatttttac
     5281 caacaaggtt ggctttgaga ctttcaaaaa cttccatgag ttttctcctt taagataata
     5341 attatactct gagacagttt ttatagagta ttagttgata actgggtaat aaggttactg
     5401 aaatcatccg gcaagggact ttctaactgc aagtcttgct ctaaaaatgg atgataaaag
     5461 gataggtaat ggcaatgcag agcctgacgt tgaataccat cttccagact accaccatac
     5521 aaatcatctc ccagcaaagg aaaaccgata tgagaaaaat ggactcggat ttgatgggtt
     5581 cgaccagtgt gcaggtgaat atagaccaag tgaatatttc cataagaagc tacaatcttg
     5641 tatgaagtat gggcatactt tccgccttta gccactcgtc tggtaataat ggaatcttca
     5701 tcacgcgcaa tcggagcaat aatttcccct tctggctcca aatgtccatc tcccttaacc
     5761 aaagcaaagt agcgtttctc gatagatttc ttctgcaact gcttgtctaa tcgtgcatgg
     5821 gcataaccgt gcttggcaaa gagcatcaag ccagaagtgt ccctatctag tctggtaaca
     5881 atgtgaacct gctgattttc ataattttgc ttgacatagt aacccttgat aaaattggca
     5941 atggtgttag agtgattgac actaggaata gaagccactc catagggttt attcaagact
     6001 agaaagtggt catcctcata gagaatatct aatggatgct caatagcctc caaggtttca
     6061 aagccttcct cagcgggaat gtcaatggta acgtagtctc caacgtccaa tagatacgtt
     6121 gcattttgcg gttgattatt gaccagaata gctccacctc gaaacttaat cttagccagc
     6181 aatcccttag aaacctcgtg cttttttaaa aaggtcttaa ccttgacatg ttcatctgcg
     6241 ataaattcaa acctcattca tccacctcac cgataaaggc atccttaaca cggttccaga
     6301 aactggtatg gctaggagtc gcgacaaagt gaatcttatg atggtcgatt tgatactcaa
     6361 tacgctcaat attacggaaa gaataaacgc tattgtcaac cgaaatagta tgataatcgt
     6421 ttcttgttgg aataagttca atcttatcct tcttaggcac aataatggaa gagcccagtg
     6481 ttcgataaac acgattatta aggctggcaa tttccgttaa ttgcaaagct tcaatggtag
     6541 ggtgtaaaac agcaccgcca agagacttgt tataggcagt actaccagtc ggtgtcgaaa
     6601 ctgttagccc gtctccacga aaacgttcaa agggaacacc atttattaca atatctgcca
     6661 ccatggttcg atcagacctg cggatgctgg cttcgttgag tgctctgaaa atcttaactt
     6721 caccattttc aagaaagacc ttcacattca gaacagggta agaaaccctt gccccagtat
     6781 ctagctgcaa attagtcact agcttgtcca actcaaaatc acgataatct gtatagaagc
     6841 ccaaatgtcc agtatgaaga ccgataaagc ggaccttgtc aagctgattt tcgtacttat
     6901 gaaaggccga caagagcata ccatccccgc caatggaaat gacaatatcc ggattggtat
     6961 cattgagtat aaactgattt ctcttcaaac gatctcgcaa ttcatacaaa accctttgac
     7021 tctgcggttt tctattggct atcagatcaa ttcgtttacc tgtattcttc atctgtatcg
     7081 tcactgtttc ctacaccgtc atttaatttt ctactcaaag gatcaaaaag tgcctgggct
     7141 tcttggatat catcacgaat ttcacccatt tcttcatcca actgatgggc gattctagct
     7201 gtaatttcca gtcgcttctt aatctcatct gggaaatccc cttggtactt gtagttgaga
     7261 gaatgttcta tcgttgccca gaaattcatg gccaaagtac gaatttgaat ttctgccaaa
     7321 atagtcttag ctccattgat ggtatcaacc gtatattcta ctaccacatg ataggaacga
     7381 tagcctgatg cttttctatg agtaatgtaa tctcgctcct gtatgattcg catatcctga
     7441 cgcttgtgca aaatatccac tacttccttg acgtcatcta caaactgaac catcacacgt
     7501 aagccagcaa tatcctgcaa atcgtgttcc aaggtcgcat aagtaatgcc acgacgagcc
     7561 attttttctt tgatgctctc aattggcttg actcgaccgg tcacaaactc aattggagaa
     7621 tgcttatttt gcttacgata ttgcttacga ataccacgaa gtttaatctt taactcacca
     7681 acagcttgaa tgtaaggatc tagaaattct tcccattcta aggtcatata ttctcccttg
     7741 ttctcatatt atccgtcaaa aatatctttg attttttctc cagattcata tacaataaat
     7801 acaatgctta ttataccata aatccgcttt caacgataaa aaaaggtaag aaaaatgaaa
     7861 catttagaaa ttgaattgaa aacactattg aaaaaagatg aatacaatcg tctaaaagac
     7921 cagttcacag gtgtcactcc tgttcttcaa acaaattact acatcgacac gcctgatttt
     7981 gaactgcgag aaaagaaagt cgctatgcgc attcgaacct ttgaagactg ggctgagttg
     8041 acactcaaag tcccgcagag tgttggaaac atggaataca accaaaaatt gcaactaaaa
     8101 gatgctgagg actatctgag taaggaagaa cttcctcaag gactagtact ggatgaattg
     8161 gcgaaacatg gtatccaaag taagaactgg caggttcttg gttgtctaac aacgcttcgc
     8221 tatgaaatga aaacagctat tggtctcatg gcactggatc agagccgata ctttgatata
     8281 acagattacg aattggagct tgaagtggaa aatcatgagc aaggcaaaca ggatttccga
     8341 caatttttag agaaaaatca gatttcctac caaaaagctc cttcaaaatt ggttcgattt
     8401 gtcaaaagta tgaaaaatag ctgaaataat ctccattttt tggtaaaata gaaaagataa
     8461 aaatacacaa atcccagttc atatatgtaa ggtaaatata actaggattt ataaagttta
     8521 cagaggacgg tctataatgt cagatagaaa aaacatgaaa cttttcgcac tcaactctaa
     8581 ccaagagatt gcacaaaaaa ttgcccaagc tgttggtgtc ccacttggaa aactatcatc
     8641 acgtcaattt tcagacggag aaatccaagt aaatatcgaa gaaagtgtcc gtggttatga
     8701 tgtttacatc atccaatcaa caagtttccc tgtcaacaac cacctaatgg aattgttaat
     8761 catggtcgat gcttgtgtgc gtgcaagtgc ccacagtatc aacgttgtcc ttccatattt
     8821 tggctatgca cgtcaagacc gcattgcttg tcctcgtgag ccacttacag caaaactagt
     8881 tgccaatatg ctggttaagg ctggagttga tcgtatcctg actcttgatt tgcatgccgt
     8941 tcaggttcaa ggtttctttg atattccagt ggataatctt ttcactgttc ccctattcgc
     9001 aaaacattac tgcgataaag gattgcttgg ttcagatgtt gttgtcgtta gccctaaaaa
     9061 ttcaggtgtc aaacgtgcgc gtagcctggc tgaatatctt gatgctccta tcgccattat
     9121 cgactaccct caagacgatg caactcgtaa cgaaggttat attattggtg atgttgaagg
     9181 taagaaagct atcttgattg atgatatttt aaatacagga cgtaccttct ctgaagcttc
     9241 taaaatcgtt gaacgtgaag gagctacaga aatttatgct gtttctagcc acggtctctt
     9301 cgtcgaggga gctgctgagc ttcttgacaa tactaatatt aaagaaattc ttgtgactga
     9361 ttcagtagca acaaaagaaa aaactcctaa aaatgtatgc tacatcactg ctagtgagtt
     9421 aattggtgat gctatcgtcc gtattcacga aagaaaacca gtcagcccac tctttgccta
     9481 caataaaaag aaataaggtg attctttgat ttatttggac aatgctgcaa cgactcctat
     9541 gtcagcagtt gctatttcag ctatgaccaa ggttatgcaa gaaacccacg gaaatccttc
     9601 tagtattcat ggtcatggtc gtcaagctgg caaactcttg cgagaagccc gtcaggaact
     9661 agcccagtta ctaaggacaa aacctcaaca tatctttttc acttctggtg ggactgaagg
     9721 caataatact accatcattg gctactgtct tcgtcaccaa gaacaaggaa aacatatcat
     9781 cacaactgcc atcgagcacc atgctgtcct tgaaacaatt gattacttgg ttcaacactt
     9841 tgggtttgaa gcaaccatta tccagccaga aaatcaagaa atcacagccc agcaaattca
     9901 aaaggcttta cgtgacgata cgattttggt ttctaccatg tttgccaata atgagacagg
     9961 aaacctactg cccatcgctg aaattggcca aatactcaag caacaccctg ctgcctatca
    10021 tgttgatgca gttcaggcta ttggtaaaat cccaattcat tcagaagaat tgggcattga
    10081 ttttctcact gcttctgccc acaaattcca tggtcctaag ggaatcggtt ttctctacgc
    10141 atctagcatg gactttgatt cctatctaca tggcggagac caggaacaga aaaaacgtgc
    10201 aggaactgaa aatctgcctg ctatcgtagg catggttgca gccctaaaag aagacctaga
    10261 aaaacaagaa gaacattttc aacatgtaca aaatctagaa accgcctttc tggcagagct
    10321 ggagggcatt cagtattacc tgaatagagg aaaacatcat ctcccttatg ttctcaatat
    10381 tggatttcct ggtcagaaaa atgacctctt actccttcgg ctagatttag ctggaatttc
    10441 aatctctact ggctcagcct gtactgcagg cgttgtccaa tccagccatg ttcttgaagc
    10501 catgtatggc gcaaattcag aacgcttgaa ggaatccctt cgcatcagtt tgtcgccaca
    10561 aaataccgtt gaagacctac aaaccctcgc aaaaacctta aaagaaatta tcggaggtta
    10621 gccatatggc atttgaaaaa atcattcagt taaaaaattg tcgttacgat tacactctta
    10681 gcccttctgt taaaaaattc accctcaaag ataacacctt ttttgaaact aaggttggta
    10741 actatgaact gactcgcctt ttggaaaaag tgccaaacag cggtgaaggc ttccaactca
    10801 aaatcatcat taacaaggaa cttacagggg ctaaaatcaa tatcactgac aagtttagcc
    10861 ttcgtctagt tgatattttc aaatcagaag accaccatat tcatcaggaa aaattctact
    10921 tcctcatgga tagcttggta gaacgtggtg tctttacaaa atcggaaaga tagagccaaa
    10981 atgtttgaac tgacctataa ggactgctat catgtagagc gtactctcaa gtatgaggat
    11041 catgaggctc tcatgttgac tttgtcagga tgtgtaacct taccagatac actttatgtg
    11101 acttctctga cttttagggg ccaaaaagtt tatcagggtc tggtcggaga cctctaccgt
    11161 tttctatctc atgcagattt tttacatcaa aactaagatt tttcttagtt ttttcttatt
    11221 tttgttgatt ttttcacaat gtttctataa aatagaagaa tagaaaggtt gtgattttgt
    11281 gaaagataaa cagtttgcta ttccaaaagc tacagcaaaa agactctctc tctactatcg
    11341 aatttttaag agatttcatg cagaaaagat tgaacgtgcc aactctaagc aaattgcaga
    11401 ggctatcggt attgattcag cgaccgtacg tcgtgatttt tcctattttg gtgaacttgg
    11461 tcgtcgtggt tttggctatg atgtcaaaaa actaatgaca ttttttgccg atttgctcaa
    11521 tgacaactct attaccaatg tcatgctggt tggtattgga aatatgggcc atgcccttct
    11581 ccactaccgc ttccacgaac gtaacaagat gaagattatc atggcctttg acctagacga
    11641 ccatcctgaa gtcggtaccc aaactcctga cgggattccc atttacggga tttctcagat
    11701 caaggataaa atcaaggatg ctgatgtgaa gactgctatc ctaactgttc ccagcgtcaa
    11761 gtcacaagag gttgctaatc tcttggttga tgctggtgtg aaaggaattc tcagtttttc
    11821 accagtccat ctgcatttac caaaagacgt ggtcgttcag tatgtcgatt tgacaagtga
    11881 actccaaacc ctcctctact tcatgcgaaa agaggattag aaagcgaaaa tcattttatg
    11941 aaaaaaccag ttattgggat tacaggaaac gaaaaagctc atccagatga tgacatcatg
    12001 atgagctacg cagcaaaagg ctttgttgaa ggcgttaaag atgctggagg gattcccatc
    12061 atcctaccga ttggtgatca agaaatggcc tgccactata tcagtttgat tgacaagctc
    12121 atcttgacag gtgggcaaaa tgtcgatcca aaattttatg gcgaacccaa aaccattgat
    12181 agcgatgact ataaccttca aagagatatc ttcgaactgg ccctcatcaa ggaagctatt
    12241 aaacagaaaa agcccatttt ctctgtctgc cgtggtaccc aactctttaa cgttgccatg
    12301 ggtggaactt tgtaccaaga tatcgaagac cattggcagg attcttctgt tgagtacaca
    12361 actcaacgct tggtaacaga accagatacc gttctccaag aaatctatgg agaaatctct
    12421 catatcaact ccttccacca ccagagcatc aaggacttag caccaaattt aaaagttgtg
    12481 gctcatgatc ctaaagatgg tatcattgag gctgtcatga gtacggatga tgtcgccttt
    12541 ctcggtgtcc aatggcatcc agaacttctt tttgaaaatc gtcccaaaga taaaaaactc
    12601 tttgactatg tcgttaatga actttagatt aaatctgtct tttcacgata actaaagtaa
    12661 ttagaatgag agacaatcaa atggtccaag agaacaatcc ccatcaattc gcaggcttct
    12721 ttaacaagtt tagtgacatg atcatcattt tggctaggcg ctaccgctcc tgaaggatga
    12781 ttgtggacca agataagaga agtcgccata tgcttgattg catagtgaag aatctctcgc
    12841 ggttcagcga tactacgagt tacagaaccg ataaaaatgg tctgctgatg gatgatttga
    12901 ttttgagtat tgagatagag tgccaccagg tgctcttgtt ttttatcccc taattcctgc
    12961 tgcatcttct tggccaactt ttgactgctg agaatacttt ccatttcaag agtctcgtgt
    13021 ttgtgaatac gatgccccag ttcaatcata gcttgtaatt ctatggcctt aacacgccca
    13081 ataccagaca aactctgcaa ttcctgcagg gtcatttttt tcaaatccgt taggcttgaa
    13141 agattgttca agactttttg ggcaatttca aaaacgctag cttgacgtgt tcctgtcctg
    13201 agtaaaatag ctagcaactc ttggttacta agcgcttcaa ctccttcctt ggccagcctt
    13261 tctcttggta atagtgaatc ttcttggaat gaaatactgt acataaaaat cctcctcact
    13321 ttattattcg tgagaaggat ggaaaattag atttttttct caattggagc cacactggct
    13381 aaaagttttt tcaaacctac ttctgggaaa ttgattttca attcctgcct agcaccgcta
    13441 cctgaaactt ccagaacagt tccctctccc catttcttgt ggagagcaat gtcaccaatg
    13501 gaccaatttg cctcgctaga tgctgatttt gcgccagctg taaattgacc aaatggaaga
    13561 ccgcttgact ggatcgattt tggggcagca ccgcgtttac ggtcttgaag agcctgagcc
    13621 aaactcatac cttgaccaaa ggaaatacta ccactgctat atgatgcctt aaagcttgta
    13681 tttgcaggac gagccagacc ttgatactca agcaagtctg aactgatttc gttaataaaa
    13741 cgagtcggac ggttataatt ggtacgacca aaaagcaagc gtgagttggc attggtcaga
    13801 tagagaattt tctctgcacg cgtgatacct acataggcta gacggcgctc ttcttctaat
    13861 tcatctggat cttcagtcgc acgactaagt ggaaagacat tttcttccat cccaatcaaa
    13921 aagacaactg gaaattcgag acctttggca gcatgcaggg tcatcaaggt cacttctgat
    13981 gtctcctgac tacctgaatc tgtgtcggca atcaaagcca agtcatttaa gaaacgactc
    14041 agtttgtcca gaccagtttc ctcttctgtc acatcagtgg tgtcatcaaa gttcttcgta
    14101 acagaaagaa actcttcgat attttcaacc cttgccttgc tttctagagt cgcttgggcg
    14161 ttaagaatat cgacataacc tgttttttct aggacggact caaccaactc tgtaatgctt
    14221 aagtggtcta gctgctcccg caaatcaagc atcatattgg caaaatccca gatagattgg
    14281 gctgccttac ccttgatacc agacaacata atattagcag aagcatccag catagacata
    14341 ttttgcaaat ttgcaaaatc acggattttc tcaactgtac ctagaccaat tccacgttta
    14401 ggctcgttga taatacgctc aaaactaatg ttgtcactca aattagcaat aaggttgaga
    14461 taagcaataa tatcgcgaat ttccttacgg ctgtagaatt tggttccgcc aaccatggta
    14521 taaggaatgt tagacttgag cagggcttcc tcaattgtac gggactgggc attagtccga
    14581 tagagaactg caaaatcctt atgaaggaag ttttgactgc gactaagttc atcgatggtt
    14641 ctggctacaa atacagcctc atccagctca tcatcagcac gatagtaaac gatttgctcc
    14701 ccatcagcgt tttgagtcca gagattttta ggacggcgat ttttattatt tttaataacc
    14761 tcgttggccg cttggagaat ggttttggtt gagcggtaat tttcctccaa caaaacaacc
    14821 ttagctttgg ggtaatcctt ttcaaagtcc aagatattct gcatatcagc accacgccaa
    14881 ccgtagatag actggtccgc atccccaacc acacagatat ttttaaaacg ggaagccaag
    14941 agtttgacca attggtactg agcgtggttg gtatcttggt actcatcaac gtggatgtat
    15001 tggaattttt gctggtagta ggtcaaaaca tcaggatttt gatcaaagag acgcaaggtc
    15061 agcataatca aatcatcaaa gtcaacggat tcagactgac gaagttcttt ttgataggtt
    15121 gtataacact gggccacaat ttgcgtatac atatcgccag cttgagcagc ataagcaaca
    15181 tcatcaatca aatcattctt agcattggaa atggtcccca aaatagttcg ttcattccat
    15241 tttttaggat ccaagttcaa ctgtttgaga atacgtttca tgagcgttcg ctgttcacca
    15301 ggatccacaa ttgtaaaatt acgattgtag ccaatatggt ccgcatcgcg acgcaaaata
    15361 cgcacacaca tggagtggaa ggtcgcaatc agacagtcct gagtagctgg attgaggcta
    15421 taagcacgct ctttcatctc acgcgcagcc ttgttggtaa aggtaatggc caagatattc
    15481 caaggattga ccagcttttc atcaatcaaa taagcgatac ggtgggttaa aacacgagtc
    15541 tttccagaac cagctcctgc catgattagc aagggacctt ctgtcgtttg caccgcctca
    15601 gcctgacggt cattcattcc atttaataat gcgttcatct tctcttcctt actcttgaag
    15661 tcaatatttc tattatatca gaaatcaggg aaaatagaaa ctttacgggg agtagcaaaa
    15721 tatagtggat tgaaactaga atactacact gtgggtttct aaaacactcg actttttcac
    15781 ccaatttttt cataaactag ctcaatacct caatagactt cctgcaaaac tagaatccta
    15841 gttcatgatt gataat
//
LOCUS       DBEJKC010000042        15610 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.042, whole genome shotgun sequence.
ACCESSION   DBEJKC010000042 DBEJKC010000000
VERSION     DBEJKC010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 15610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15610
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.042"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            44..199
                     /locus_tag="ACL3G6_001483"
                     /pseudo
     CDS             44..199
                     /locus_tag="ACL3G6_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            399..3674
                     /gene="rexB"
                     /locus_tag="ACL3G6_001484"
     CDS             399..3674
                     /gene="rexB"
                     /locus_tag="ACL3G6_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HGR0545989.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMNFLDLENLTDEDKRADLLLIFEKVTDYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYCFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            3671..7321
                     /gene="addA"
                     /locus_tag="ACL3G6_001485"
     CDS             3671..7321
                     /gene="addA"
                     /locus_tag="ACL3G6_001485"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HGR0545990.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAANELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWELAKTFQTFMSHFVEVYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYIFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLTSLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7491..8669
                     /locus_tag="ACL3G6_001486"
     CDS             7491..8669
                     /locus_tag="ACL3G6_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0545991.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERDIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            8878..14952
                     /gene="iga"
                     /locus_tag="ACL3G6_001487"
     CDS             8878..14952
                     /gene="iga"
                     /locus_tag="ACL3G6_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HGR0545992.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVSDKG
                     VPEVQPELPEAVVSDKGVPEVQPELPEAVVSDKGEPEQVAPLPEYKGNIEQVKPETPV
                     EKTKEQGPEKTEEVPVKPTEETPVNPNEGTTEGTSIQGAENPVQPAEESTTNSEKVSP
                     DTSSENTGEVSNKPSDSTTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSN
                     QETEKPVQPAEETQTNSGKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSG
                     NTTSENGQTEPEPSNGNSTEDVSTKSNTSNSNGNEEIKQENELDPDKKVEDPEKTLEL
                     RNVSDLELYSLSNGTYKQHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKND
                     KILYKITAKVEKLQQEIESRYKDNFPFYLAKKGTEETTNFTSFSNLVKAINQNLSGTY
                     HLGASLNANEVELSTDDKSYIKGTFTGQLIGEKDGKHYAIYNLKKPLFENLSGATVEK
                     LSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESS
                     FKGRIVNTYETTDSYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLV
                     DRDAQIQDSYAEGDINNVKHFGRVAGVAGNLWDRTSGDVRHAGSLTNVLSDVNVTNGN
                     AITGYHYTGMKVANTFSSKANRVFNVTLEKNEVVSKESFEERGTMLDASQIASKKAEI
                     NLITPPIVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKATIVKYGNLVK
                     ENSILYQKELLSAVMMKDDQVITDIISNKQTANKLLLHYKDHSSEKFDLRYQADFANL
                     AEYSIGDSGLLYTPNQFLYHQDSIINQVLPELNRVNYQSDAVRNTLGISPEVKLTELY
                     LEEQFTKTKEHLAENLKKLLSSDAGLVTDNEVMTGYIIDKIKRNKEALLLGMSYLERW
                     YNFSYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYAISLAS
                     HHGTTDLFSTLENYRKVFLPDKTNNDWFKSQTKAYIVEEKSNIEEVKTKQGLVGTKYS
                     IGVYDRITSATWKYRNMVLPLLTLPERSVFVISTISSLGFGAYDRYRNKEHQANGDLN
                     SFVEKSAHETAERQRDHYDYWYRILDEKGREKLYRNILLYDAYKFGTNHTEGKATEVA
                     DFDSPNPAMKHFFGPVGNKVGHNGHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHNS
                     DQDIYLGGYGRRSGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSKEGERLQVL
                     DPTTRFKDATDLQKYVHNMFDVVYMLEYLEGKSIVKKLNVYQKIEALRKIENQYLTDP
                     ADGNDVYATNVVKNLTEDEAKKLTSFDSLIDNNILSAREYKAGTYERNGYFTIKLFAP
                     IFSALSGEKGTPGDLMGRRIAFELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGK
                     ERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPRYGTK
                     TINNVDELQKLMDEAVLQDAKERNYYYWNNYNPETDSAVHKLKRAIFKAYLDQTNDFR
                     RSIFENKK"
     gene            14996..>15610
                     /locus_tag="ACL3G6_001488"
     CDS             14996..>15610
                     /locus_tag="ACL3G6_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR0545993.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGTSTYHYLDYS
                     TLTQTERVQLKQGRPDESKESYALVYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DKKRKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVDYLELDDR
                     TVSPVEQPKVVTDKGEPEVQPALPEAVVTGKGKTEVQPTLPEAVV"
BASE COUNT         5223 a         2980 c         3248 g         4159 t
ORIGIN      
        1 ctatttttgg ttcattttac tatagttcaa tcattctatc aagaatattg aatatataaa
       61 ggcacgtaat attaaaactt cttctgatat cgaattagag tccgatgttg atggcgataa
      121 atcagacaat ctacccgtcg acattaagac actgggacaa cacattgaag tgtattccgt
      181 acctaagaaa caatcataaa actcaaagcc ttgttaccga ggctttttta ttatatgatt
      241 ttcagtggcc agacttattc tatctaatac aagtaaagct aagtatttaa gatttagcag
      301 atgatgaaga aaagaaagga tggcctaaat attttaacag atttacgagg ctaatcatgg
      361 tataatatag ggtgatgaaa aattccaacg aggctgagat gaaattactt tatactgata
      421 ttcgaacttc tttgacagaa attctaacaa gagaggcaga agagctagtt gcagctggca
      481 agcgggtctt ctacattgcc cccaactctc tttcttttga aaaggaacgc gccgtgctgg
      541 aatgcttgtc ccagcaggct tctttttcga ttaccgtcac gcgctttgct caaatggctc
      601 gttatctggt cttgaatgat ttaccagtta aaactactct tgatgatatc ggtcttgggt
      661 tggcctttta caaatgcctt gccgaactcg atcccaagga cttgcgtgtt tatggagcta
      721 ttaagcagga tcctcaattg atccagcagt taattgagct ttaccatgag atgaccaaat
      781 ctcagatgaa ttttttggac ttggagaatt taacagatga ggataagagg gcggatttac
      841 tcttgatttt tgagaaagta acagactatc ttaatcaagg tcagttagcc cagggaagtc
      901 agttgtccca tttgattgag gctattgaga atgacaaggt aagtagtgat tttaatcaaa
      961 tcgccttggt cattgacggc tttactcgtt tttctgctga ggaagagcgg gttgtggact
     1021 tacttcacgg caaaggtgtt gagattgtta tcggggctta tgctagtaag aaagcctata
     1081 ccagtccttt tagcgagggc aatctctacc aagccagcgt aaaatttctc catcatctgg
     1141 cttctaaata ccaaacgccc gctcaggact gttctcaaac tcatgagaag atggatagtt
     1201 ttgacaaggc ctctcgtttg ttggagtctt cttatgactt ttcagaactc gctttggatg
     1261 tcgatgagaa agaccgtgaa aatttacaaa tctggtcttg tttgacgcaa aaggaggagt
     1321 tggagctagt agcccgtagc attcgtcaga aattacatga gaactcagac ctgagctaca
     1381 agcattttcg tattctcttg ggggatgtag cttcttacca gttatctctc aaaaccattt
     1441 ttgaccagta tcagattcct ttttatcttg gtagaagcga agccatggct catcatccct
     1501 tgactcagtt tgtcgagtct attttagctt taaaacgtta ctgttttcgt caggaggatt
     1561 tgattaatct tcttagaact gacttgtata ctgacctcag tcagtctgat attgatgctt
     1621 ttgagcaata tatccgctat cttggtatca atggcttgcc agcctttcag caaatcttca
     1681 ccaaatccca ccatggaaaa tttaatcttg agcgtttgaa tgtcctccgc ctgagaattt
     1741 tagcacctct tgaaaccctc tttgccagcc gaaaacaaaa ggctgaaaac ctcctacaaa
     1801 aatggagtgt ctttctaaaa gaaggagctg tgaccaagca gttacaagat ttgacaacca
     1861 ctttggaagc tgtagaacag gaaagacaag ccgaagtttg gaaggctttc tgccatgttt
     1921 tagaacaatt tgcgactgtt tttgctggtt cacaggttag tctggaagac ttcctagcct
     1981 tgctccattc tggaatgagt ttgtcccaat accgtaccat tccagcaaca gtggacactg
     2041 ttctggtgca gagttacgat ttgattgcac cattgactgc tgactttgtc tatgctattg
     2101 gactaactca ggacaattta ccaaaaattt ctcaaaacac cagtcttctg acagatgaag
     2161 aaaggcaaaa tctaaaccaa gcgaccgaag aaggcgttca attactgatt gccagcagtg
     2221 aaaatctcaa gaaaaatcgc tacactatgc tttccttagt caattctgct cgtaagcagt
     2281 tgttcttgtc ggctccaagc ctttttaacg aaagtgaaag taaggaatct gcctatcttc
     2341 aagagttgat ccattttgga tttaggcgga gagagaagag gatgaatcac aaaggactgt
     2401 ctaaggagga tatggggtcc tatcacagtc ttttgtctag tctggttgcc tatcaccagc
     2461 agggtgagat gagcgatact gagcaagatt tgacttttgt caaggttctg tcgcgtgtca
     2521 taggtaaaaa actagatcag caaggtctgg aaaatccagc catcccaatc agtccaagca
     2581 gcaagacctt agccaaggac accttgcaag ctctctatcc tgccaaacag gagttttacc
     2641 tgtctacgtc gggtttgaca gagttttatc gcaatgaata cagttatttc ctacgctacg
     2701 ttttaggctt gcaggaggaa ttacgtttgc gtcctgatgc ccgtagtcac gggaatttct
     2761 tgcatcgtat ctttgaacgc gccttgcagt tgcctaatga agattccttt gaccaacgtc
     2821 tagaacaagc tattcaagaa accagtcaag aacgcgaatt tgaagctatt tatcaagaaa
     2881 gtttggaagc ccagtttacc aaggaagttt tgcttgatgt tgcacggaca actggacata
     2941 ttctccgaca caatccagcc atcgaaacaa tcaaagaaga agcaaatttt ggtggaaaag
     3001 accaagcctt tattcaatta gacaatggac gcagtgtctt tgtacgaggc aaggtggacc
     3061 ggattgaccg tttgaaagct aatggagcga taggagtagt agactacaaa tccagtctga
     3121 ctcagttcca gtttcctcat ttctttaatg ggctcaattc tcagttacca acctatcttg
     3181 ctgccctaaa aagagaaggg gagcagaact ttttcggcgc catgtacttg gaaatggctg
     3241 aacctgtcca atctctgatg gcggtaaaaa gtctggcagg agcagtggta gaagccagca
     3301 aatctatgaa ataccaaggg ctcttcttgg aaaaagaaag cagttattta ggcgaatttt
     3361 ataacaaaaa caaggcgaat caactgacag atgaggaatt tcagctccta ctggactaca
     3421 atgcctatct ttacaagaaa gctgctgaga agattttagc aggccggttc gccatcaatc
     3481 cttatactga aaatggcaga agcattgccc catacgtcca gcaacatcag gctattacag
     3541 gctttgaagc caattaccat ctgggccaag cccgtttcct agaaaagttg gacctagctg
     3601 atggcaagcg tctggtcgga gaaaaactca agcaagcttg gcttgaaaaa ataagagagg
     3661 agttgaatcg atgaagctta ttcccttttt aagtgaggag gagattcaaa aactgcaaga
     3721 agcagaagca aattcgagca aggaacagaa gaaaactgcc gagcaaatcg aagctatcta
     3781 cacttctggc cagaatatcc tggtctcagc atcggctggt tctggaaaga cctttgtcat
     3841 ggcagagcgc attctggacc aattggcgcg tggtgtcgaa atttctcaac tctttatctc
     3901 aacctttacc gtcaaggctg caaatgaact taaagaacgt ttagagaaaa aaatcagcaa
     3961 gaaaatccaa gaaacagatg atgtcgacct caaacaacac ttgggacgcc agttggcaga
     4021 cctaccaaac gctgccatcg gaaccatgga ctctttcaca caaaaattcc ttggcaaaca
     4081 tggttatctg cttgatattg cacctaattt ccgtatttta caaaaccaaa gcgagcaact
     4141 tcttctcgaa aacgaagtct ttcatgaggt ctttgaagcg cattaccaag gtaaacagaa
     4201 agagaccttt agtcatttgc tgaaaaactt tgctgggcgt ggcaaggacg aacggggtct
     4261 gcgccagcag gtctataaaa tctatgactt cctccaatcc accagtaatc ctcaaaagtg
     4321 gctgagtgaa tctttcctca aaggctttga gaaagctgat tttaccagtg aaaaagaaaa
     4381 actgactgag caaatcaaac aagccctttg ggatttggaa agctttttcc gttaccatct
     4441 ggataacgat gccaaggagt ttgcaaaggc tgcctattta gaaaatgttc agttaattct
     4501 ggatgaaatt ggctccctaa atcaggagtc cgatagtcag gcttatcagg cagtgcttgc
     4561 gcgtgttgtc gccatctcta aggagaaaaa cggtcgagct ctgactaatg ccagtcgtaa
     4621 ggctgatttg aagcccctgg ctgatgccta caacgaagag agaaagaccc agtttgctaa
     4681 actaggacaa ttatcagacc agataaccat tctcgactat caagaacgtt atcatcaaga
     4741 cacatgggaa ctagctaaaa ccttccaaac ctttatgagt cattttgtgg aggtttatcg
     4801 tcagcgcaaa cgccaggaaa atgcctttga attcgctgat atcagccatt acaccattga
     4861 gattttagag aatttcccac aagttcgtga gtcttatcag gagcgcttcc atgaagtcat
     4921 ggtcgatgag tatcaggata ccaaccatat tcaagaacgg atgctggaat tgttgtctaa
     4981 tggccacaat cgctttatgg tgggagatat caagcaatcc atctatcgtt tccgtcaggc
     5041 agacccgcag attttcaatg agaaattcca acgctatgcg caaaatcccc aagaaggcaa
     5101 gctcattctc ctcaaggaaa atttccgtag tagttcagaa gtgctgtcag caaccaatga
     5161 tgtctttgaa cgtctcatgg accaagaggt cggcgaaatc aactatgata acaagcacca
     5221 gcttgttttt gccaatacca aactgactcc caatccagac aacaaggcag aatttctcct
     5281 ctacgacaag gacgatacag gtgaggaaga agagagtcaa acagaaacga aactaacagg
     5341 cgaaatgcgc ttagttatca aggagattct gaaacttcat caagaaaaag gtgttgcctt
     5401 taaggaaatt gcccttctga cctccagccg cagtcgtaat gaccagattc tcctcgccct
     5461 gtctgagtac ggaattcctg tcaaaactga cggagagcaa aacaattatc tccaatccct
     5521 agaagtgcaa gtcatgctag acactcttcg tgtcattcac aatcccctgc aagactacgc
     5581 cttggttgcc cttatgaagt ctccaatgtt tggttttgat gaggatgagc tagcacgttt
     5641 gtcccttcag aaagcagagg ataaagtcca cgaaaatctc tatgagaaac tggtcaatgc
     5701 acaaaaaatg gcaagtagtc aaaaaggctt gattcacaca gctctagctg aaaaactaaa
     5761 gcaattcatg gatatcctag cttcttggcg cttgtatgcc aaaacccatt ctctctatga
     5821 cttgatttgg aagatttaca acgaccgttt ttattatgac tatgttgggg ctttgccgaa
     5881 tggtcctgct aggcaggcca atctctatgc cctagcactg cgtgctgatc aatttgaaaa
     5941 gagcaatttc aaaggtttgt cgcgttttat tcgtatgatt gaccaagtct tagaagccca
     6001 gcacgatttg gcaagcgtag ccgtcgcacc gccaaaagat gcagtagagc tcatgaccat
     6061 ccacaagagt aaagggctgg agtttcctta catctttatc ctcaatatgg atcaagattt
     6121 caacaagcaa gactctatgt cagaagtcat tctcagtcgt cagaatggtc ttggtgtcaa
     6181 atatattgcc aagatggaga caggggcagt agaagaccac tatcctaaaa ccatcaaact
     6241 ctccattcct agtctgacct ataggcagaa cgaagaggaa ttacagctag caagctattc
     6301 tgagcagatg cgtttgctgt atgttgctat gacgcgggct gagaaaaagc tctatcttgt
     6361 cggcaagggt tctcgtgaaa agctggaatc caaggaatac ccagcagcca aaaatgggaa
     6421 actaaatagc aatactagac tgcaagcacg gaatttccaa gattggcttt gggctatcag
     6481 taaagtgttt actaaggaca agctcaactt tagttatcgt tttattggcg aagatcagtt
     6541 gaccagagaa gctatcggag agttggaaac caagagtcct ctccaagata gctcccaagc
     6601 agacaatcgt cagtcagata ccatcaaaga agctctggaa atgctgaagg aggtggaagt
     6661 ttataatact cttcaccgcg cagctattga acttcctagt gttcaaaccc caagtcaaat
     6721 caagaaattc tacgaaccag ttatggatat ggaaggtgtc gagattgctg gtcaaggtca
     6781 gtcagtaggc aagaaaatca gcttcgattt gccagatttt tcaaccaaag aaaaggtaac
     6841 tggagctgag attggtagtg ctactcacga actcatgcag agaattgacc tcagccagca
     6901 actaaccctt actagcctaa cagaaacact caaacaagtt caaactagcc aagctgtcag
     6961 agacaagatc aatcttgata aaattcttgc tttctttgac acagcactcg gtcaggaaat
     7021 tcttgctaat accgaccatc tctatcgcga gcaacctttc tccatgctca aacgagacca
     7081 aaagagtcag gaagactttg ttgtccgtgg tatccttgat ggctatctgc tttacgaaaa
     7141 caaaattgtt ctgttcgact acaagacaga ccgctatgat gaaccaagtc aactcgtaga
     7201 ccgctatcgt ggtcagttag ctctatacga agaggcttta tcacgagcct attcgattga
     7261 aaatattgaa aaatacttga ttttactcgg taaagacgag gttcaagttg taaaagtata
     7321 acttatactc ttcgaaaatc tcttcaaacc acgtcagctt cgccttgctg tatatatggt
     7381 tactgacttc gtcagttcta tccacaacct caaaacagtg ttttgagctg actgcggcta
     7441 gctttctagt ttgctctttg atttttattg agtattagaa aggagacctc atgacacttc
     7501 cagttagaaa atccctgcac gatgcagttt tacaggcttc gaaagcggat acttgggaac
     7561 aagctaccaa ggaatggaat gaagtttcct tgatttttaa cggtatcggc cgtagcaatt
     7621 gtgtctgtgg aaatgccatc aaatacgctt atgaactctt taacggtgtc acaggccaac
     7681 gcctctttcc aattggtagc gactgtgttc gtcattttca tcgattgtcc cttgaccagc
     7741 aattggaaga ggaagaaaaa ctgctcagaa aggttgaaaa tctaaccaga aaagctcaga
     7801 aaaaggaaaa aatcaaggtc aataaaagtg actttgacga gcgacttcta aaatggctct
     7861 gggaaaaagg tgttttcaaa cccaatcgtg gcaatcaatt tgcgcctgag agagactacc
     7921 agcttttcct agaagtcttt cagggaggaa gttggaccaa ggcggaacca aagaaaaagg
     7981 ctcggatgga agaagtcctt gaaaagtgta tcaaaccctt tttacttggg aaatcggatg
     8041 accaactcta ccttgtcaag ctaggcaagg agaaaattga ctacgaacaa gaactccgta
     8101 tccaggcaga gaaagaacgc aagaagaggg ataaaatcgc caagcaatat gcagacaatc
     8161 tggttctagc catgggaccc gcagagcgtg cttatcaaga ttactttggc tttacagaga
     8221 ccctgactca agaagaacgc aagtgggaaa aaattctttt tggtaaaaat agagcagaac
     8281 gggatatcaa ggccaaacaa taccaaaaag agctggaaaa agaccaacga attgccagtc
     8341 aggatccaat tgaaagaaaa cagaagcaga cttggctcct caattcctat tttcgtgagc
     8401 ttcctgaaga aaaagctcga ttttctaggc tcttattaga atatcgaaaa agtggtgaag
     8461 tacccttttc aactgaatac ctgtccgatc atctcatcga ctttttctat aaaatgaaag
     8521 cctttgaatt tgaaatcgca ccagaacaag tccgagattt tctaaaaaaa agcctgcagg
     8581 aagaccatcg ctcatcagca caaggaagct ggatagaagg aattctcctc aactgcctca
     8641 aaccattttt agaacgatta gtgatatgag taacacctac cgtgtaaatt tcatggtagg
     8701 tgttattgta cctcaaaata atataaaaca aagtatgaaa gcgcatctca attttaagac
     8761 ttttttgtaa attaagagta taattaaggt atactgcctt ttctatagat aatatataat
     8821 acactaatat aataaaggtc tttgtaacat atataaattt tatttcaagg aggaataatg
     8881 gaaaagtatt ttggtgaaaa acaagagcgt ttttcattta gaaaattatc agtaggactt
     8941 gtatctgcaa cgatttcaag tttatttttt atgtctgtat tagctagttc atctgtggat
     9001 gctcaagaaa ctgcgggagt tcactataaa tatgtggcag attcagagct atcatcagaa
     9061 gaaaagaagc agcttgtcta tgatattccg acatacgtgg agaatgatga tgaaacttat
     9121 tatcttgttt ataagttaaa ttctcaaaat caactggcgg aattaccaaa tactggaagc
     9181 aagaatgaga ggcaagccct agttgctggt gctagcttag ctgctctggg aattttaatt
     9241 tttgctgttt ccaagaaaaa ggttaagaat aaaacggtat tacatttagt attggttgcg
     9301 ggaataggaa atggtgtctt agtttcagtc catgctttag aaaatcatct tttgctaaat
     9361 tacaatacgg actatgaatt gacctctgga gaaaaattac ctcttcctaa agagatttca
     9421 ggttacactt atattggata tatcaaagag ggaaaaacga cttctgattt tgaagtaagt
     9481 aatcaagaaa aatcagcagc cactcctaca aaacaacaaa aggtggatta taatgttaca
     9541 ccaaattttg tagaccatcc atcaacagta caagctattc aggaacaaac acctgtttct
     9601 tcaactaagc cgacagaagt tcaagtagtt gaaaaacctt tctctactga attaatcaat
     9661 ccaagaaaag aagagaaaca atcttcagat tctcaagaac aattagccga acataagaat
     9721 ctagaaacga agaaagagga gaagatttct ccaaaagaaa agactggggt aaatacatta
     9781 aatccacagg atgaagtttt atcaggtcaa ttgaacaaac ctgaactctt atatcgtgag
     9841 gaaactatag agacaaaaat agattttcaa gaagaaattc aagaaaatcc tgatttagct
     9901 gaaggaactg taagagtaaa acaagaaggt aaattaggta agaaagttga aatcgtcaga
     9961 atattctctg taaacaagga agaagtttcg cgagaaattg tttcaacttc aacgactgcg
    10021 cctagtccaa gaatagtcga aaaaggtact aaaaaaactc aagttataaa ggaacaacct
    10081 gagactggtg tagaacataa ggacgtacag tctggagcta ttgttgaacc cgcaattcag
    10141 cctgagttgc ccgaagctgt agtaagtgac aaaggcgaac cagaagttca acctacatta
    10201 cccgaagcag ttgtaagcga taaaggcgta ccagaagttc aacctgaatt acccgaagca
    10261 gttgtaagcg ataaaggcgt accagaagtt cagcctgaat tacccgaagc agttgtaagt
    10321 gataaaggtg aaccagagca ggtagcacca ttgccagaat ataaggggaa tattgagcaa
    10381 gtaaaacctg aaactccggt tgagaagacc aaagaacagg gtccagaaaa aacggaagaa
    10441 gttccagtaa aaccaacaga agaaacacca gtaaatccaa atgaaggtac tacagaagga
    10501 acctcaattc aaggagcaga aaatccagtt caacctgcag aagaatcaac aacgaattca
    10561 gagaaagtat caccagatac atctagcgaa aatactgggg aagtatccaa taaacctagt
    10621 gattcgacaa cctcagttgg agaatcaaat aaaccagaac ataatgactc taaaaatgaa
    10681 aattcagaaa aaactgtaga agaagttccg gtaaatccaa atgaaggcac agtagaaggg
    10741 acctcaaatc aagaaacaga aaaaccagtt caacctgcag aagaaacaca aacaaactct
    10801 gggaaaatag ctaacgaaaa tactggagaa gtatccaata aacctagtga ttcaaaacca
    10861 ccagttgaag aatcaaatca accagaaaaa aacggaactg caacaaaacc agaaaattca
    10921 ggtaatacaa catcagagaa tggacaaaca gaaccagaac catcaaacgg aaattcaact
    10981 gaggatgttt caaccaaatc aaacacatcc aattcaaatg gaaacgaaga aattaaacaa
    11041 gaaaatgaac tagaccccga taaaaaggta gaagatccag agaaaacact tgaattaaga
    11101 aatgtttccg acctagagtt atacagtttg tcaaatggta cttataaaca acacatttcg
    11161 ttagagcaag ttccaagcaa tccaaatagc tactttgtta aagtgaaatc ttcttcattc
    11221 aaagatgtat acctaccagt agcatcaata tcagaggaaa gaaaaaatga taaaatcctt
    11281 tataaaatca cagcaaaagt agagaagctt cagcaggaga tagaaagcag atataaagat
    11341 aattttccct tctatctagc taagaaggga acagaagaaa caacaaactt tacttccttt
    11401 agtaatctgg tcaaagctat aaaccaaaat ctctctggaa cctatcattt aggagctagc
    11461 ctgaatgcta acgaagtgga gcttagtact gatgataaat cctatatcaa gggaaccttt
    11521 actggtcagt tgattggtga aaaagatggt aagcattatg ctatttacaa cttgaaaaag
    11581 cctctttttg aaaacttgag tggtgctaca gtagaaaaac tgagtctaaa aaatgttgct
    11641 atttcaggga aaaatgatat tggttcactg gcaaatgaag ctacgaatgg cacaaagatt
    11701 aaacaagttc atgttgatgg tgttctggct ggagaacgtg gtgtcggtgg tttgttggct
    11761 aaggcagacc aatcaagcat cgcagagagc agtttcaagg gaagaattgt caatacctat
    11821 gaaacgactg attcctacaa tattggcggt ctggtcggtc atttaacagg aaaaaatgcg
    11881 tctattgcta aatccaaagc gacagtaacc atttcgtcaa acaccaatag gtcagatcag
    11941 actgtcggtg gtcttgcagg tctagtagac cgagatgcac agatccaaga tagctatgct
    12001 gaaggtgata tcaacaatgt caagcacttt ggtagagtcg ctggagtggc aggcaatttg
    12061 tgggatcgaa cttctggtga tgttaggcat gctggaagtt tgaccaatgt tctcagcgat
    12121 gttaatgtaa caaacggaaa tgccatcact ggataccact atacaggaat gaaggtagct
    12181 aatacattta gtagtaaggc taatagagtt ttcaatgtca ctttagagaa gaatgaggtc
    12241 gtcagcaaag aatccttcga ggaaagagga acaatgctag atgcttctca aattgcaagc
    12301 aaaaaagcag aaatcaatct tatcactcca ccaatagtgg aacccctctc aacaagcggt
    12361 aagaaagaca gtgatttttc taagatagcc cattatcaag ccaaccgtgc tttggtttat
    12421 aagaacattg aaaaattgtt acctttctat aacaaggcga ccatcgtgaa atacggaaac
    12481 ctggttaagg agaacagtat cttatatcaa aaagaactct tgtctgcagt tatgatgaag
    12541 gatgaccaag taatcacaga tattatttcc aacaaacaga ctgcaaacaa actcttgctt
    12601 cactacaagg accattcatc tgaaaagttt gatctcaggt accaggctga ttttgccaat
    12661 ttggcagaat atagcattgg agatagtggg cttctctata cgccaaatca attcttgtat
    12721 catcaagatt ctattattaa ccaagtgctg cctgaattga atcgagtaaa ttatcaatca
    12781 gatgctgtta gaaatacact tggaatttca ccagaagtga agctaacgga gttatatctt
    12841 gaagaacaat ttaccaaaac gaaagagcat ctagcagaga acttgaaaaa acttttatca
    12901 tctgatgcag gtttagtaac agacaatgaa gttatgacag gatatataat agataaaatt
    12961 aaacggaata aggaagcctt acttcttgga atgagttatt tagaacgttg gtataacttt
    13021 agctatggtc aagtgaatgt caaagaccta gttatgtatc atccggactt ctttggtaaa
    13081 ggaaatactt caccattaga tactctgatt gagttaggta aatctggctt taacaatctt
    13141 cttgctaaaa acaatgtcga tacttatgct atcagccttg ccagccatca tggaacgaca
    13201 gatttgttta gcacgttgga aaattaccga aaagtctttc taccagataa aaccaataat
    13261 gactggttta aatcacagac taaggcttac attgtcgaag aaaaatccaa tatcgaagag
    13321 gtgaaaacga agcaaggact agttggcact aagtattcta ttggtgtcta tgaccgtatc
    13381 actagtgcca catggaaata ccgtaatatg gtactacctc tacttacctt gccagaaaga
    13441 tccgtatttg tcatttcaac catatctagt ctaggttttg gtgcttatga tcgctatcgt
    13501 aataaagaac atcaagcaaa tggtgatctt aatagctttg ttgaaaagag tgctcacgaa
    13561 acagcagagc gtcaacgaga tcactatgat tattggtatc gtattctaga tgaaaaaggg
    13621 cgtgaaaagc tttatcgaaa tatcttgctt tatgatgcct ataaatttgg aactaatcat
    13681 actgaaggaa aggctacaga agtagcagat tttgatagtc caaatcctgc aatgaaacat
    13741 ttctttggac ctgttggaaa taaggttgga cataatggac atggtgctta tgctacaggg
    13801 gatgcagtat attatatggg gtatcgcatg ctagataagg atggagctat tacgtatact
    13861 catgagatga cgcataattc agatcaagat atttatcttg gtggttatgg aagaagaagt
    13921 ggacttggac ctgagttctt tgctaaaggc ttactacaag caccagacca accaagtgat
    13981 gcaacgatta ctatcaattc tatattgaaa cattcaaaat ctgatagtaa agaaggagaa
    14041 cgattacaag tacttgatcc aactacgaga tttaaagacg caacagatct tcaaaaatac
    14101 gtccacaata tgtttgatgt tgtttatatg ttggaatatc tcgaaggtaa atctattgtt
    14161 aagaaattaa atgtatatca gaaaatagaa gctctcagaa aaatcgagaa ccaatatcta
    14221 acagatcctg ctgatggaaa tgatgtttat gctactaatg ttgtgaaaaa tttgactgaa
    14281 gatgaagcta aaaaattgac gagctttgat agtttgattg acaataacat tctttcggct
    14341 cgtgagtata aggctggcac ttatgagaga aatggctact ttactataaa actctttgca
    14401 ccaatctttt cagcattgag cggtgagaaa ggaactccag gtgaccttat gggacgaagg
    14461 atagcttttg aacttctagc tgctaaagga tttaaagatg gtatggtacc atatatttcc
    14521 aaccaatacg aagaagatgc taaacaacaa gggcaaacta tcaatcttta tggtaaagaa
    14581 cggggcttgg tgaccgatga gcttgttttg aaaaaggtat ttgatggtaa gtataaaact
    14641 tgggcagaat ttaagacagc tatgtaccaa gaacgggtgg atcagtttgg aaacttgaag
    14701 caggtgacct ttaaagatcc gacaaaacca tggccaagat atggcacaaa gactatcaat
    14761 aatgtggatg aattgcagaa actaatggat gaagctgttt tgcaggatgc aaaagaacgt
    14821 aattattatt attggaataa ctataatcca gaaacggaca gtgccgtcca taagttgaag
    14881 agagcaatct ttaaagccta tcttgaccaa acaaatgatt ttagaagatc aatttttgag
    14941 aataaaaaat agtgtttact attaggaaat aaaaagtgaa tgtggaggat tagaattgtc
    15001 attattaaaa aaagataaat tttccattcg gaaaataaag ggtattgttg gttcggtatt
    15061 cttggggagt cttttatttg caccgtcagt tgttggtaca tcgacttatc attacttaga
    15121 ttatagtact ttgacacaaa ctgaacgtgt tcaactcaaa caaggtagac ctgatgaatc
    15181 aaaagagtca tatgctttgg tttatgaaaa agacgcatta ccaaacacag gaagttctca
    15241 atctattatg actgcattgg gtttgttagc tatcgggagt cttattgtga ttatcacaaa
    15301 agataaaaag aggaaaaaaa tcgctacatt tttgattgta ggggcgacag gtttagttac
    15361 actatcaact gcttcagcac ttaatttgaa tgctaacatc catgagtctg gacgtgatgg
    15421 tgtgttgcaa atttctggtt acagatatgt tgattacttg gagcttgatg atagaactgt
    15481 ttctccagtt gagcaaccca aagttgtgac cgacaaaggc gaaccagaag ttcagccagc
    15541 gttaccagaa gctgttgtaa ctggaaaagg gaaaactgaa gtacaaccga cattaccaga
    15601 agctgttgtg
//
LOCUS       DBEJKC010000043        15400 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.043, whole genome shotgun sequence.
ACCESSION   DBEJKC010000043 DBEJKC010000000
VERSION     DBEJKC010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 15400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15400
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.043"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(213..560)
                     /locus_tag="ACL3G6_001489"
     CDS             complement(213..560)
                     /locus_tag="ACL3G6_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0545994.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(671..2446)
                     /gene="spxB"
                     /locus_tag="ACL3G6_001490"
     CDS             complement(671..2446)
                     /gene="spxB"
                     /locus_tag="ACL3G6_001490"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HGR0545995.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2653..4896)
                     /locus_tag="ACL3G6_001491"
     CDS             complement(2653..4896)
                     /locus_tag="ACL3G6_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGR0545996.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPTHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWIISIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(4906..5277)
                     /locus_tag="ACL3G6_001492"
     CDS             complement(4906..5277)
                     /locus_tag="ACL3G6_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HGR0545997.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            complement(5288..5683)
                     /locus_tag="ACL3G6_001493"
     CDS             complement(5288..5683)
                     /locus_tag="ACL3G6_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HGR0545998.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5867..5965
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6049..6840
                     /gene="thiD"
                     /locus_tag="ACL3G6_001494"
     CDS             6049..6840
                     /gene="thiD"
                     /locus_tag="ACL3G6_001494"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGR0545999.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7050..7682)
                     /gene="thiE"
                     /locus_tag="ACL3G6_001495"
     CDS             complement(7050..7682)
                     /gene="thiE"
                     /locus_tag="ACL3G6_001495"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGR0546000.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITVAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLIGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7675..8478)
                     /locus_tag="ACL3G6_001496"
     CDS             complement(7675..8478)
                     /locus_tag="ACL3G6_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGR0546001.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYVAQVCLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSKNQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(8478..9002)
                     /gene="thiW"
                     /locus_tag="ACL3G6_001497"
     CDS             complement(8478..9002)
                     /gene="thiW"
                     /locus_tag="ACL3G6_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HGR0546002.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAIIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            complement(9007..9699)
                     /gene="tenA"
                     /locus_tag="ACL3G6_001498"
     CDS             complement(9007..9699)
                     /gene="tenA"
                     /locus_tag="ACL3G6_001498"
                     /EC_number="3.5.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050334 - thiaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HGR0546003.1"
                     /translation="MEFTDIAMELSKKAWQVSFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9710..10360)
                     /locus_tag="ACL3G6_001499"
     CDS             complement(9710..10360)
                     /locus_tag="ACL3G6_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HGR0546004.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCVLFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10362..11747)
                     /locus_tag="ACL3G6_001500"
     CDS             complement(10362..11747)
                     /locus_tag="ACL3G6_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0546005.1"
                     /translation="MGLELRAIQSPIFPEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSPPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTEVASKEVASSPELFHMDRTTCEFGNRSLFSIADFTFYQGISCILGDNGVGKSTF
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRDFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11748..12308)
                     /locus_tag="ACL3G6_001501"
     CDS             complement(11748..12308)
                     /locus_tag="ACL3G6_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0546006.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(12570..12658)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12867..13496)
                     /gene="thiE"
                     /locus_tag="ACL3G6_001502"
     CDS             complement(12867..13496)
                     /gene="thiE"
                     /locus_tag="ACL3G6_001502"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGR0546007.1"
                     /translation="MFHKELLKLYFICGTTTCQGKDLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(13498..14280)
                     /gene="thiM"
                     /locus_tag="ACL3G6_001503"
     CDS             complement(13498..14280)
                     /gene="thiM"
                     /locus_tag="ACL3G6_001503"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGR0546008.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKKFKRVK"
     gene            14376..14507
                     /locus_tag="ACL3G6_001504"
     CDS             14376..14507
                     /locus_tag="ACL3G6_001504"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546009.1"
                     /translation="MKIKEQTRRLTAGCSKHCFEPVDKTDEVSSKHCFEVVDRTDVV"
     gene            complement(14562..15230)
                     /locus_tag="ACL3G6_001505"
     CDS             complement(14562..15230)
                     /locus_tag="ACL3G6_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HGR0546010.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
BASE COUNT         4647 a         3390 c         2821 g         4542 t
ORIGIN      
        1 aatcaactcc aagatgtcat acaaggactg gagaaggagg tgataaagtc catcgttaat
       61 cggagatgga ctagaatgct ttttgaaagc agatgagtat tatatgcaat ttctttatat
      121 aaaaagaccg gattgctccg atctttcaat agttcatatt ctcaatttct attttaaaaa
      181 tagctaaggt taacgtcaaa tgactacgcg acctatttca tacgataaaa atcaagcact
      241 agaccagcag gtccttgaac taataaggac tctgttcccc aatcggttac agttggtccg
      301 tgtaaaacct ttataccaag ctcgttcaac cgtttgtagt tctggtctac atcctcaacc
      361 tcgatatgaa taatgattcc tgactgaaag ttttccaaag gaaccaaatg attttgtgac
      421 aacataaggc agtgactacc aatcgtaaac tgagcaaaac catcatcagc ataatctgcc
      481 tttttatcca aaatatgctc caagtcagca cagacttggg gaacatttga aacgataata
      541 tctaattgat ttaaattcat ttactctcct ccataaaaag accggattgc tccgatcttt
      601 taaagttctg ctctatgaaa atcaaagaat aaagtctaca agtttcatat ttgattttcg
      661 gcgagaggaa ttatttaatt gcgcgtgatt gcaatccttc ttcttccaag aagagacgga
      721 atggtacgag ttcttctgct tcgtattttt ccttgaaggc tttgatagct tcttctgagt
      781 gaagttttgg atccaattca agtacttcta ctggaagtgg acggtgttga gtgatgcgag
      841 catcgatgac aacagtttta ccttctttgt tcaatttaac agcttctgca acaactgcat
      901 cgatgtcttc gatacggtca actgtgaatc caacagctcc ttgagcttcc gcaattttag
      961 cgtagtcagc gtttgtgaag tctacaccaa acaagtgttt gtttgtatct tcgtatttgt
     1021 tcttgatgaa gccgtactca gcatttgaga agacaaggtt gataactgga aggtcgtatt
     1081 gaacgtttgt gataacgtct gggtagcaca tgttgaatgc tccgtcaccc atgatgttcc
     1141 atacttggcg atctggattg tctttcttag cagcgatacc accaggaagg gcaataccca
     1201 ttgtcgcaaa gagtggagat gtacgccaca tgttcttagg tgtcatgtga aggtgacgag
     1261 tagatgtttg agtagtgtta cctacgtcga ttgagtagat agcgtcttga tcagcatgtt
     1321 tgttgattgc attgtaaact tgatacaatt gcaattcacc ctcagtttta ccttcgagtt
     1381 tgttcatgta atcacgccag ttttggttgt tcttaacgtt tgcacgccac catggagttg
     1441 attcaactgg gtttactttg tcaaggatag ctttagctgc ttgaccagca tcaccaagga
     1501 ttgaagcgtc aagggcatga cgtttaccaa gtttgtaagg gtcgatatcg acttggatga
     1561 atttttcagt gttcttgaat gcttcgtaaa cttcagcaaa tgggaagttt gaaccaagga
     1621 aaagaactgt gtctgcttca aagaccactt cgttggctgg tttccaacca acacggtaag
     1681 cagaacctgt caaaccttca tagttccatt cgaaagcttc aaagttttta ccagttgtga
     1741 tgattggtgc tttgatttta cgtgacaatt cagtaatcac ttcaccagct ttaacaccac
     1801 caaatccagc atagataact gggcgttcag cattgttcaa gatttcaaca gctttgtcga
     1861 tttcaacttc gttcaaagca ggagcgatga atgagcgttc gtatgaacct gaaccgtagt
     1921 atgagttttc atcgatttct tggaaaccga agtttactgg aatttcaaca acagctggac
     1981 cttttttaga aattgcagca cggcaggctt cgtcaattac ttttggcaat tgctcagcgt
     2041 aagctacacg tttgttgtaa acagcgatac cgttgtacat tgggttttgg ttaagctctt
     2101 ggaaagcatc catgttcaat tcgttaactg gacgtgatcc aaggatcgct aggaatggag
     2161 tgttatccat agctgcatcg taaacaccgt taatcaagtg agtcgcacct ggaccacctg
     2221 aaccaactgc aaccccgatt gagccgccga atttagcttg cataaccgct gcaagagcac
     2281 ctgtctcttc gtggcgaact tgtaagaagc ggatatcttt gtcttcagcc aaagcgtcca
     2341 tcaatgagct gagtgttcct gatgggatac cgtagattgt atctacgccc catgttttca
     2401 atacgttaag cattgctgca gatgcagtaa ttttcccttg agtcataatg ataactctcc
     2461 ttcaattttt ttaaacttgg agaatacgat tacatagaat tggaaacgtt ctccaaattt
     2521 ttactattcc actgtatcat atttatgctg acttttctaa aaatctgctc aaaactctct
     2581 attctctatt ctaatacagt tttgaaagtg ttgtcgtttc tgttttataa caaagaaatc
     2641 tagtcattac ttttagtcta ttttactaaa atttaacaga agggaactgg tcagaacaga
     2701 tacagaacta aaggccatgg ctagacctgc caattctggg ttgagagcca gtccaacacc
     2761 tgaaaagact cctgctgcaa tcggaattcc gacaacattg tagataaaag cccagaaaag
     2821 attgagtaga attcgatgaa aggttttctt actcatatca aaggcacgaa ccactcctaa
     2881 aagattattg gttgtcaaca ccaaatctgc tgactcgatg gcgatatctg ttccagcacc
     2941 catagcaatt cccacatctg ctacactaag ggcaggagcg tcattgatac cgtccccaac
     3001 aaaggctact ttacctgact gttgcagttt atggatttca tgggcttttt cttctggcaa
     3061 gacgcctgca atgacctctt caattccgat ttgatctgca atagcacgcg ccacaccagc
     3121 attgtctcct gtcagcatga ctgttcggag accacgtttt tttagctgac tgatggctag
     3181 cttagcattt tccttaggaa tatcttgcaa agcaagcaag cctttgattt cattgtcaac
     3241 agctaaaaac acaactgtct tagcttcttt ttctagttct tctagtttat cttgataagt
     3301 attagaaata tccatgccat ccagcatttt agcatttcca agtaaaactt gttttccatt
     3361 gattcgccct gaaacacctt tcccgtgcaa ggcctgaaaa ttttcaacag tttgaaactc
     3421 aagtccagct tcactcgctc gcttaacgat agcctcagcc agtgggtgtt gagaagcatc
     3481 ttccaaggag gctgccaatc caaacacttc tacttcgtcg ccgatgatat ctgttaccac
     3541 aggtttccct tccgtcaaag tcccggtctt atcaaagaca agagtttgaa ctttctggat
     3601 ttcctgtaag acagttccat ttttgaggag aacccccatc ttggcactac gtcctgtccc
     3661 caccataagg gctgtcggtg ttgcaagtcc caaggcacaa ggacaggcga taatcaaaac
     3721 cgccactccg tagagaagag aggacacaaa gctagctcca agcacaacca cactatccct
     3781 gagcaagacg aaccaaaccc aaaaggtcat gattcctaaa atgacaacta ctgggacaaa
     3841 aatccctgaa atcttatccg tcaagtcctg aatcggcgca cgacttgtct gagctttctt
     3901 cacaaaatcc acaatctgag ccaaaacagt ctctgagcca actttttctg ctctaaagac
     3961 aagcgttcca ctatgattga tggttgagcc aatgacagta tctccaactg tcttgtccac
     4021 aggcagactc tcacctgtca ccatggattc gtcaatacta gagacacctt ctactacgac
     4081 accatcaaca gcaatctttt caccgggacg cactcgaatc aggtcgccta ccttgacttg
     4141 ttccaaagga acttggacat aactatcatc actcaagact tctgcggttt tagcttgcaa
     4201 gtccagtaat ttctccacag cttgggacgt attttttctc attttttcct caaaaactgc
     4261 tcccaaaaga acgaaaaaga ggataaatcc agcactttcg aagtaaacag ggagaccagc
     4321 aaagagagca actaggctat agaaataagc cactagagtt cccagcgcaa ccaaggtatc
     4381 catgttggca ttgtgctttt taaaactggc ccaagcactc tggatatatg gcttacctgc
     4441 aactaacata ataggcgttg ttgctagaaa ggttccccaa tgcatgactt gatgactaat
     4501 gctacctgtc aacatcccaa tcatgagaat cacaagaggc acagtaaaga tactaataat
     4561 ccaaaaacgt tgcaggagag atagagattt tcgagtcttc tcaacgactg tatagcttcc
     4621 cttttgcatc ttcatgccac aagaaaattc atgtcgccct aattcttgag gtgtaaaacg
     4681 aatgactttc tcctcatcta cgccgattgg ttccaagata ccttcttctt caaacagaat
     4741 ttccttataa cagtttgaag gagtagcacg atgaaaggta atctcagctg gaattccctt
     4801 ttgaagctgg atatgggttg gatgatagcc tttttcagct cggatacgga ttttttgaat
     4861 gccattttct aagcttgctt tcacaatttc tgtcatagtc tccacctact ctacaatcat
     4921 cttgccgtgc atcatgttca taccacaagc aaagccaaac tctccagcct gctcaggcgt
     4981 gatttccact acatactctt cccccattgg caggttcgca tgtacaccaa aatctggaaa
     5041 aacaatttga tccagacatg gtgaaggatc cttgcgatca aagacaatgc gtgctggcac
     5101 tgatttcttg aggacaatca actcaggagt atagcctccc atgacttcca ctcgaatctc
     5161 ttggtatccg tttttttgct gggctttttg tccagatttt tcaggctttt tgaaaaacca
     5221 aaacaagata aacgcgataa gggcaataca aataatggtt acaatactat ttaacatgac
     5281 gtttccttta catacaatta catcttactt ctgttacagc acttgatttc ttctctgaaa
     5341 tcacagcttc caagtcttcc aagtcagtct gagtaaattc acattctaca atcaagtcag
     5401 ccaacaaatt cctaatccta cgggaacaaa ccttgtcttt gatatcttgg acaagtaaat
     5461 cccgactttg gtctagagtt aaaagggctg aataaacaaa ggacttgcct tcttttttcc
     5521 gagtcaaaca ctctttctca actagacgag ccaaaagtgt ctgaaccgtg gacttggacc
     5581 agtcaaaccg ctctgccaaa accctaatca aatccgtact ggtctgctcc ccctgcatcc
     5641 aaataatctt catgacctgc cattctgcat ctgaaatctg cattaccata cctccaaaat
     5701 ctacatttgt caattacact catcagtata ctcttaaaat ctacatttgt caattataga
     5761 aataatattt tcttcgaaaa atagaatttt aatcatttga aaaacgattt gcagtcaaat
     5821 attactatat aaacaataaa aatatgctat actaaagaaa aaagaaaaca accactaggg
     5881 gtgcgtaaag ctgagattaa cgactgttag atccctctga ctcaatctag gtaatgctag
     5941 ctgatggaag tggaaatgat aatggggact agcagtcttc tattgccttt ctaaaacaga
     6001 ctagcttgtt cttaagaata caaacttcag ttggttggga ggttttagat gacttattta
     6061 cccgttgctt tgaccattgc agggactgac cctagtggtg gtgctggcat tatggcagat
     6121 ttaaagtcat tccaagcgag agatgtctat ggaatggctg ttgtaaccag tcttgtcgct
     6181 caaaatacca gaggtgttca gctaatcgag cacgtttctc ctcaaatgtt gaaagcccaa
     6241 ttggagagtg tcttttctga tattccacct caggctgtaa aaactggaat gttggctact
     6301 actgaaatca tggaaatcat ccaaccctat cttaaaaaac tggattgtcc ctatgtcctt
     6361 gatcctgtta tggttgctac aagtggagat gccttgattg actcaagtgc tagagactat
     6421 ctcaaaacaa acttactacc tctagcaact attattacgc caaatcttcc tgaagcagaa
     6481 gagattgttg gtttttcaat ccatgacccc gaagacatgc agcgtgctgg tcgcctgatt
     6541 ttaaaagaat ttggtcctca gtctgtggtt atcaaaggcg gacatctcaa aggtggtgct
     6601 aaagatttcc tctttaccaa gaatgaacaa tttgtctggg aaagcccacg aattcaaacc
     6661 tgtcacaccc atggtactgg atgtaccttt gctgcagtga ttactgctga actagccaag
     6721 ggcaagagtc tttaccaggc agttgataag gccaaggcct ttatcacaaa agctattcaa
     6781 gatgcccctc aactcggtca tggttctggt ccagtcaacc atacaacttt taaagattaa
     6841 gaaaaaaaac tctctagttc ccactttaag ggaattagag agtttttata ctcttcgaaa
     6901 atctcttcaa actacgtcag cttccatctg caacttcaaa acactgtttt gagctgactt
     6961 cgtcagtctt atctaaaacc tcaaggcagt actttgagca acctgcgact agctttctag
     7021 tttactcttt gattttcatt gagtattaat taggaaagaa tgtcatgcaa ctttgttaaa
     7081 aaggcttgcg tttttgcctc aatatcttct gcttgcatca aatcacgtac aacagctaca
     7141 ccagctatac ccgtgccgat aagttggtca atattctctg atgtcaagcc gccaatagca
     7201 actactggaa tggcaaccgt ttgacaaatt gttttcaagg ttgaaatcag ggtgatgggt
     7261 gcattttcct tggtggttgt cggaaaaatg gctcctgtcc ccaagtaatc tgcacctgat
     7321 ttctccgctt ccagagctct tttaaccgtt ttagcggtga caccgaggat tttttcagga
     7381 cccaagactt tgcgagctac cgaaactggt aattcatcat ctccgatatg cagacctgct
     7441 gcatcaaccg caagacaaac atccaaccga tcatcgatta tcaagggtac ctgataagca
     7501 actgttattt ccttgacttg ttttgccagt tgataatatt gattggttgt gagatttttt
     7561 tctcgcaatt ggactatggt aacccctgaa cggcaggccg tctcaacttt tgcaagaaag
     7621 ctttccacgg aatcttgata gcgattggtt accagatata gtctaagtgc ttctctattc
     7681 ataaacctct cctttgatgg tatctagcca attttcatct cttcttagga gcgaaagctg
     7741 attgagtact tggtaacgaa attcttccaa tcccattcct tgaacaacta ttttctcagc
     7801 agcgatattg agataagaga ctgctaagca agaagcttca aaaccagtct ttccttggct
     7861 gagaaaaacg gctgttaagg ctccaaccaa atctcctgtc cctgttatcc agtctaattc
     7921 agtacagcca ttctccagta cagcgacctg atttttcgaa acgatgaggt ccttggggcc
     7981 agtaactaag aatgacatac caggataggt ctgacaccaa tctttcaaga cttgaagcaa
     8041 atcctccgtt tcttgatctt tagcactcgc atcgacccca acgccgtggt gctttaatcc
     8101 aacaagactt cgaatttctg acatgtttcc tttaaggacc gtaggtctat agtctaaaag
     8161 gtctttaact aagctcttac gaatggatga agtcgttacg ccaaccgcat ctactaccat
     8221 tgggagacaa acttgagcta cataagaagc tgctatacgg attgctttct ccttctcagc
     8281 tgacaaatgc cccaaattga tgaagagagc ctgactttgc ttagtaaaat caagaacctc
     8341 acggggatca tctgccatga caggtttgca tcccagagcc aaaatcccat ttgccagcat
     8401 ctcacaagaa atctcattgg tcatacagtg aatgagggaa ctagagccta taggaaaggg
     8461 atttgtaaat tcctgcatca gtctatcctt tcactaaaga aatatccctg cactttttta
     8521 aagaattcct gcttgattaa aaatcgaaag gcaataaagg aaatcgctgt accaatcaag
     8581 gttgctccga aaaatcgagg cgtgtagata aaccagctaa gcttagcagc tgatcctgta
     8641 aagagtacca taacaggata ggaaacaata gaaccaataa tacctgttcc cacaatttct
     8701 cccaaggcag aaaagtaaaa ttttcgaccg tacttataaa agagacctgc tagaagggct
     8761 ccaaaagtcg ctcctgtgag agctaaaggc ggaatccctt gagtcgtcat acggataatg
     8821 gctgtcactg tagccatagc caaggcataa acaggtccca tcatgattcc cgctagaata
     8881 ttgactacac tggacatcgg tgccattccc tcaattcgaa agataggtgt aaggactaca
     8941 tcaagggcaa tcatcataga taaaatggtt aatttgtgaa cttgtaattg gtgctttctc
     9001 atgtttctat tcttctcctt tttctaaaga ctgtaaatcg ctcttccatg tctggtgttg
     9061 gtaggccatt tcccaaaact tggcttccat atgaacactg atgtggaagg catctagcat
     9121 tttttgcttg tctgtctcgt cactttctcg atagagctga ttgaccagtg ctccctcctc
     9181 tctgatctgt tgctctaact catccgtaat ataagtttca atccattgtt gatagagagg
     9241 atttggtgat ggtttaagat taagtgattt gcctatatca tggtataacc aaggacaagg
     9301 aagcaagctt gcaaaagcta tggctaagtt cggttctgca aattgcctat aaatatgaga
     9361 aatgtaatga taacaggttg gagcgattgg atgttgctcc atttcctggt cgttgatttc
     9421 caattccttg aaaaattgtt ggcgaataaa taactcaccc tccactaaac cctgagcatt
     9481 ttgtttcaaa agtcttttca tctcttggtt tgaagtctta tcagccaaaa gatgatagat
     9541 ttctgagaaa gccttcagat agtaggcatc ctgaatcagg taatagcgga aaatggcagg
     9601 ttctaaattc ccctcttgta attgtaaaat aaagggatga tgaaaggaaa cctgccaagc
     9661 tttcttggat aattccatcg caatatctgt aaattccata ataactcctt tataaaaata
     9721 gactggtttg aagcaataaa aagaaaagca ggtagattaa ttttgttttt ttaggaatat
     9781 aaaaagtccg atagctattc ttcaactgtg catgttcgtc atatccgtga gcagatagag
     9841 ctctcaggta aagatggcgc cacctaaaga ctgtcatcag aaccttactg taaatcaagg
     9901 gcgaccaaaa atgtagttct tgaccacgta ataggcaagc ttctttgagg gacttgattt
     9961 cttgctgaat gagaggaaaa gaattgaata ccacaatcaa ggcataggac caagagcgtg
    10021 atagcccctt ttgagccaag tacaagagaa gctcttttag tgaaatagag gaaacaaaga
    10081 caaggccgat acaaactgtc acaaaggccc tcgttccaag catgactgcc tgtgaagcat
    10141 ctccgtgtaa ctgaactgcc cagtagttgg caaaagatgg taaaatggca agtatgatca
    10201 tccaagctaa cattttaaat cgacggtaat agagcataaa gagaacacaa aatgcgacta
    10261 ccgaaagatt cagagcaatc gaaggaatga aagatgtttc caaggataaa atcagcaaga
    10321 agagactgat aatcggtgtc tgggttgcta ctttgaccat actatctcac ctccccttgg
    10381 gtattgctac tctgagatgt aagtggtttg gtaatggtca cttctttcac atgccgaaga
    10441 ccctgactag tcatctcaat ccaataatca accacagaaa tcaaagggtc taaacgatga
    10501 ctaatgagca gaaaacttct tccttgattc ctctcctcca caatccactt gcaaaaataa
    10561 tggcaggctc tatcatccaa acctgcaaaa ggttcatcta gcaagatcac ggaagcctta
    10621 ctggtcaaga tggtcaagag ctgaagaatt ttttgctgac caccacttaa ttgataggga
    10681 ctcttatcga ctgcctgctc caaatcaaaa tctcgtaaag cttgaaaaat ccgctgattt
    10741 ctttcagaat caggtccatc taattgaagc tcctctcgca gactgactcg aataaactgc
    10801 ttctcagctt cctgaacaac accagtcaga tcacggtaca aactcttttt ctttttcagg
    10861 actgtcccct tccatgcaat gcgcccctta tacttttgaa attgaagaat agagcgaaag
    10921 aaggttgatt tcccgacacc attgtcaccc aggatacagg aaatcccttg atagaatgtg
    10981 aaatcagcaa ttgaaaagag ggagcgattt ccaaactcac aagtcgttct atccatatgg
    11041 aatagttccg ggctagaagc aacttccttt gaagcaacct ctgtcatctc ataggaaggg
    11101 atttgaaaca cttcccttag ttttccgtct cttagctcaa ccatatggtc gatataggct
    11161 ttatagtcag ataaatcatg gtcgcacaaa ataactgtct tcccatcaag agccaactct
    11221 tttagaatct ccaatatctc gattctgctc ttgcggtcaa tggaagcgaa gggctcatcc
    11281 aagagatata ccctaggatt catggcaaag aggacagcca gcgctgcttt ttgcttttcc
    11341 ccacctgata ggtgatgaat gggacggtgt aagattgcct cgcaacgaca ttgctggaca
    11401 acctctgcta ttttagaatc aatttcctga aggtgatagc cgatattctc caaggtgaaa
    11461 atcagctcct caaacaagtt ctccatggta aattgatgat tgggattttg aaagagaatg
    11521 ccaaccttct ggacacgtgc gatgatagaa agctgactga cctcgctccc atctatcagg
    11581 acttgaccac tatagggagg agaactgact tgggcaatga cttgaaaaag gctggatttt
    11641 cctgaaccac tgctcccaac taacaaggta aaggcttgcg catgaaaagt aaaatcaaac
    11701 ggctcaggga agattggaga ctgaatcgct cgtagttcca gacccatcta tgcttttcct
    11761 ccagttgcaa actgatgata gagtttgaca atggcacgaa ccaagatggt acagaagaaa
    11821 taaacagaaa taaaacgtac cacaagtaag gaaaggacaa acggaaggga aaaggcgtag
    11881 taacctaact taatgtattc atagacaaag ctaacaagcg taatcccaat actattagca
    11941 gttagagaga gccaactttc atagcgattc ttagttacga taaaaccaaa ttcacttccc
    12001 aaaccttgaa ccaagccaga caaaagagct cctagaccaa attggctacc ataaaggact
    12061 tcagcaagcg cagctagcac ttctccaatc gttgcacttc cgactctcgg aacaaagatg
    12121 gcagcaatgg gcgcagccat acaccagaga ccgaagagga tttcattggc aaaggcctgc
    12181 aaaccaagag gtgttaagag tagactgaga atattataca catatcctga accaacgaaa
    12241 accccaccaa aaaagataga caagaaagca agcaagataa catcttttaa ctgccatttt
    12301 ttcaacataa aaaactcctt ttttaaaaga aaagtggggc actcaagaag accgacctaa
    12361 atactttgta tagcagattg attttagaac agtacacagg aatgctaaaa tatttctaga
    12421 aattaatttg aattttctaa ttgatttgtt cgcatcttat ttcaatctac tatatcatct
    12481 tcatccagtt tcgtaaaaga aaaaactcta attacagata cgaattagag ttcagcttac
    12541 aagattagac agttcttttc gacatacgaa aaaaacattt cacatttccc ttcgccagtc
    12601 ttaactgtat caggttcaat gggtatcatc tcagcctaaa gcaccccaaa tgcctttatt
    12661 atttaattat gtgattatta taacacacat tttatactag ttcaagaaat tgaactggaa
    12721 atacagcctt gcactcacaa agacagcaga tctttctttt gcaaaaaata aatgacctgt
    12781 ttgatgaatt agccattcaa gctgaatcta gacatagttt tttaaaaaag gaaaatccta
    12841 cttacttaga atccaaggat agatatctat tgttcactca tttcccgaac agttttttct
    12901 atattttttg catacgatat tgccgaaatg attgaaacgc catccatatt ggtctttata
    12961 atgtctttaa tatgtttcgt ctgtatccca ccaattgcaa ctaaaggcat ttgtggcaat
    13021 agttttctca tcaattcaag accttcataa cctatagcac caccagcatc atcctttgac
    13081 tgggtatcaa atacaggccc aacaccaaca taatctacat attcaacttt tgattgttga
    13141 aattcttcct cgttttttat agaaagacca attattttat ctggcatcaa ttttctaatt
    13201 tcatcaacac caatatcatc ttgacctaca tgtacgccat cggcgtcaat ttccattgcc
    13261 aaatcgatat cgtcattaac gataaatgga acattgtatt ttttacaaag ttctttaatt
    13321 tggatagcta gctcaagttt ttctaagcct tctaaagcac cctcaccttt ttctcgaaat
    13381 tgaaataagg ttataccacc ttttaaggct tcctcaacga ctgtatatag atcttttcct
    13441 tggcaagtag tcgttccaca aataaaatat agttttagta attctttatg aaacatctta
    13501 cttcactctt ttgaatttct tgacatcttc atctgtaatt tcatataagg catttataaa
    13561 ttcaacttta aatgttccag gaagatgtcc atttggacgt ttttccgcca tttctccagc
    13621 gatattgtaa accaacattg ctgtttctaa tgatttcaat tcttgacctt tttcaagtcc
    13681 gataaagctt gctactacag ctcctaataa gcatcctgtc ccaatgactt tcggcatcat
    13741 agcactacca ttatgaatcg ttaccacttc tccattaaca gcaatggcat ccacttcacc
    13801 tgttactact attggaatat tgaacttctc atttgctgct agagcaattt cgtcaatatt
    13861 atctacgccc gcactatcta ctcctttaga tgccacatct attcctacta aagaggcaat
    13921 ctcgccagca tttcctctaa tcgctgctag tttataattg ttgattagat catctgctac
    13981 tttttttcta tattctcctg ctccacaggc tacaggatct aaaactgctg ggacattata
    14041 tttctccgca attttcagag cagcttggta taatttccaa ttttcatctg tcaatgttcc
    14101 tatgtttatt aataaaccac cagcatactt taataagtcc tctaaatctg ctggaaactc
    14161 actcatggct ggtgaggcgc ccagtgctac taatccattt gctgtgaaat tttttactac
    14221 atcattggtg atgcaaatga ccaaaggtgc tttttctttt aataatttta aacttgtcat
    14281 attgaaatcc ttccttttca ctttatacga tctactaatt tcgatttatc tttagttgag
    14341 aatttttttc atttacattg aatgatttat actcaatgaa aatcaaagag caaactagga
    14401 ggctaaccgc aggttgctca aaacactgct ttgagcctgt agataagact gacgaagtca
    14461 gctcaaaaca ctgttttgag gttgtggata gaactgacgt ggtttgaaga gattttcgaa
    14521 gagtcttacc tcatcaaatt tgtaaatatc atgagccttc tctagacatc gtaaccaata
    14581 tcaaaaaaag ctaattctaa agcgactgct tgattccagc gttgctgaag ttctgtcaaa
    14641 tcttctcgat ttttaccgac acgattgagt tcgtcaacca gaaattgaac ccactctgca
    14701 aagaaaggac ctctgtggag attgatccat tccgaatgaa tatagacttc aggtagagcc
    14761 aaatctttag aaccccagtc taaatagaga ccttctgcaa tgaccagcat aaccaaaaga
    14821 tgggcatagt ctgatgaagc cactgccgaa tacattagat cctgaaaggc ttttgttaca
    14881 gggtgcaaag tcacttctag atagtcattc tctgctactt ttaactcttt aaaagccttt
    14941 tggaaataac catcttcatc tgcttcaaga aagcctagtt gcttggcaaa acgaagcttg
    15001 gattcaagtt tatctgcgtg agctacgcag gcacccagca tggataagaa ggcatcaaag
    15061 aagtgataat cttgaatcag atagtccttt aagaccttat tctcaattgt ccccgcaaaa
    15121 agttccttaa caaaacgatg attgattgca gcctgccaat ccttctgact gctttttaat
    15181 aattctccaa cagtcaaacc tggctgaaat gcatagtctt gtgtttccat atttacttct
    15241 cctctcttta cttgttagta attaataaaa cagcaagaaa tatcaagcaa aatcgtaatt
    15301 ccacttgatc cttttaaagc acatcgagag catttgcaga gagctaacta aacaagccta
    15361 tccagtttat ataaacaaaa aactccaatt acaatcaaga
//
LOCUS       DBEJKC010000044        14964 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.044, whole genome shotgun sequence.
ACCESSION   DBEJKC010000044 DBEJKC010000000
VERSION     DBEJKC010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14964
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.044"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..393
                     /locus_tag="ACL3G6_001506"
     CDS             <1..393
                     /locus_tag="ACL3G6_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HGR0546011.1"
                     /translation="DHVQRNKNGQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKP
                     ESPKPTEEPEEESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLK
                     NNLLFGTQDNNTIMAEAEKLLALLKESK"
     gene            741..815
                     /locus_tag="ACL3G6_001507"
                     /pseudo
     CDS             741..815
                     /locus_tag="ACL3G6_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397816.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
     gene            815..1195
                     /gene="dhaM"
                     /locus_tag="ACL3G6_001508"
     CDS             815..1195
                     /gene="dhaM"
                     /locus_tag="ACL3G6_001508"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HGR0546012.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQTQLAELEINK"
     gene            1654..2367
                     /locus_tag="ACL3G6_001509"
     CDS             1654..2367
                     /locus_tag="ACL3G6_001509"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HGR0546013.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2381..3028
                     /locus_tag="ACL3G6_001510"
     CDS             2381..3028
                     /locus_tag="ACL3G6_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546014.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSDDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            3166..3819
                     /locus_tag="ACL3G6_001511"
     CDS             3166..3819
                     /locus_tag="ACL3G6_001511"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HGR0546015.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3829..4293
                     /locus_tag="ACL3G6_001512"
     CDS             3829..4293
                     /locus_tag="ACL3G6_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGR0546016.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4306..5574
                     /locus_tag="ACL3G6_001513"
     CDS             4306..5574
                     /locus_tag="ACL3G6_001513"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HGR0546017.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALFLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5588..5848
                     /locus_tag="ACL3G6_001514"
     CDS             5588..5848
                     /locus_tag="ACL3G6_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546018.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5859..7220
                     /gene="pdrM"
                     /locus_tag="ACL3G6_001515"
     CDS             5859..7220
                     /gene="pdrM"
                     /locus_tag="ACL3G6_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HGR0546019.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            7374..8342
                     /locus_tag="ACL3G6_001516"
     CDS             7374..8342
                     /locus_tag="ACL3G6_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HGR0546020.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8358..9350
                     /locus_tag="ACL3G6_001517"
     CDS             8358..9350
                     /locus_tag="ACL3G6_001517"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HGR0546021.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            9568..10611
                     /locus_tag="ACL3G6_001518"
     CDS             9568..10611
                     /locus_tag="ACL3G6_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HGR0546022.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     RVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10657..12360
                     /gene="lpdA"
                     /locus_tag="ACL3G6_001519"
     CDS             10657..12360
                     /gene="lpdA"
                     /locus_tag="ACL3G6_001519"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003001382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HGR0546023.1"
                     /translation="MALEVIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKV
                     SMELESEEDGYLIAILKGEGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTS
                     NDDGKSDDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTY
                     LHNAEIIENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTV
                     HKGIGTITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESSLVMTSDDILEMNE
                     VPESLVIIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGM
                     TILTGTKLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCI
                     KVNEYMETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIY
                     TLPEVAAVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVITDKKYGEILGV
                     HIIGPAAAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKK
                     K"
     gene            12424..13413
                     /locus_tag="ACL3G6_001520"
     CDS             12424..13413
                     /locus_tag="ACL3G6_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HGR0546024.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13486..14556)
                     /gene="xerS"
                     /locus_tag="ACL3G6_001521"
     CDS             complement(13486..14556)
                     /gene="xerS"
                     /locus_tag="ACL3G6_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HGR0546025.1"
                     /translation="MKREILLERINKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAINLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
BASE COUNT         4589 a         2688 c         3242 g         4445 t
ORIGIN      
        1 gaccatgttc aaagaaacaa aaatggtcaa gctgatacca atcaaacgga aaaaccaagc
       61 gaggagaaac ctcagacaga aaaacctgag gaagaaaccc ctcgagaaga gaaaccgcaa
      121 agcgagaaac cagagtctcc aaaaccaaca gaggaaccag aagaagaatc accagaggaa
      181 tcagaagaac ctcaggtcga gactgaaaag gttgaagaaa aactgagaga ggctgaagat
      241 ttacttggaa aaatccagga tccaattatc aagtccaatg ccaaagagac tctcacagga
      301 ttaaaaaata atttactatt tggcacccag gacaacaata ctattatggc agaagctgaa
      361 aaactattgg ctttattaaa ggagagtaag taaaggtagc agcattttct aactcctaaa
      421 aacaggatag gagaacggga aaacgaaaaa tgagagcaga atgtgagttc tagttctcat
      481 ttttttcatg aaaatgtgca aaatatagta gattgaaact agaatagtat acctctactt
      541 ctaaaacatt gttagaaatc gatttgactg tcctgttctt atttcatttt actatatctt
      601 aacagatagt gtaaataaag ataaactatt tactggctaa ttgatcagtt aaacactagt
      661 taaggagtaa tgatgaaaaa aagaacaata ctattattga tggccagtct gttagctctt
      721 gtcttaggag catgtggttt cttggacata ttgatcctgg atcattctca tcaggattac
      781 tctttactgc tattttagaa actggggtgg tttgatggaa agtattggta ttggtcttgt
      841 tatcgtttca cattccaaac acattgcaga aggtgttgtt gaactgatta gtaaagtagc
      901 taaagatgtt ccgattactt atgtaggagg aaccgagggc ggaggaattg gaacgagttt
      961 tgatcaagta gatagggttg tttccgaaaa tccagcagat actttacttg ccttttttga
     1021 cctaggttct gctaaaatga acttaaaaat ggtgactgat ttcagtgata aaagtatcat
     1081 catcaacagg gttccaattg tagaaggtgc ctataatgca gctgctcttc ttcaggctgg
     1141 tgcagaactg tcagttattc aaacacagtt agcggagctt gaaatcaata aataaggaat
     1201 tttactataa ctctttttat aggtaagcta ttgattatct caactataaa atgttaagta
     1261 aatgatttca aaatcagaaa gggattgctt tatgcagttc ctttttattt taacaggagt
     1321 gaaactatag tgtttctaaa ttgtgaatca atcaaaactg attgtgatgg gactattcta
     1381 gctttagaat ccttcaaaaa ttaaaattta aggcaatcaa ttacttggaa gagtatgaaa
     1441 gcatttagtt tataggaatt ctaggtctag aattacacat atatttatga agacagggtg
     1501 ctcgatagtt agtattgttc tattctgaaa gatttgagct gtcagttgta tagaaagtgt
     1561 tcgaattttt tttaagtgat taaattagtt aattgtatga ggtgctttat gatataatgt
     1621 tcttaatgaa ttttcagaaa ggaaaacctc aaattgttct acaaatttct actcttcgac
     1681 ctcgaccaca ctcttcttga ttttgatgct gctgaggatg tggctttgac ccaacttcta
     1741 aaagaagaag gagttgcgga tattcaggct tataaagatt attacgttcc tatgaacaag
     1801 gctctctgga aagacttgga gctgaagaaa atcagtaaac aagagctggt taacacgcgc
     1861 ttttctcgtt tattttctca ttttggacag gaaaaagacg gtagttttct tgcccagcgt
     1921 taccaatttt atctcgctca gcagggacaa acactatcgg gcgctcatga tctcttggac
     1981 agcctcattg agcgtgatta taacttgtat gctgcgacaa atggcattac tgccattcag
     2041 acaggacgtt tggctcaatc tggtctagta ccttatttca atcaagtctt tatctcagaa
     2101 cagttgcaaa ctcaaaagcc ggatgctctc ttttatgaaa agattggcca gcaaattgct
     2161 ggatttagta aagaaaagac gctgatgatt ggagattctc taaccgccga cattcaaggt
     2221 ggcaataatg cggggattga cactatctgg tataatcctc atcacctcga aaatcacaca
     2281 caagcccagc cgacttacga agtctattct taccaagact tgctggattg tttagataaa
     2341 aatattcttg aaaagatcac attttaaagg agattagcta atgactacaa aaaaagctaa
     2401 tattactatt gaagagtaca ttgaaatgtc tgaagttgat tttaatgaag ctgttaatta
     2461 tgaatttaca tctgacactt gtcaattagc aaatagtatt tatcaatctc tttttaagtt
     2521 ttttgataag aaaaatttct ctgacgattt aatttttact tggaaatctc catcattagt
     2581 caaagaaggg gattatattg ggagaaggga ttcacaagta gataatctta gagtaatagg
     2641 aaatatattt ccgaattatc ttactaatcg aaaatatagc ctcaatatga atcgtaatgg
     2701 ctgtatggga gattttcctc atgacttttt tgatatatac ctagatcatg tagcaaaata
     2761 tgcctacgaa caaaaagtta ataatattaa agagtattat cctttaaaaa gagcgatttt
     2821 acaccaagag aatgcattgt attttcgatt tttttctaat tttgacgact ttttagaaaa
     2881 aaattattta aagactatat ggcaagtttc taaagaaact cctttttctg aaatggattt
     2941 taatatgttt aaaaatattt cagaaaagat aatcttcgaa agaggtagta aaatgcttaa
     3001 tgatttaaaa agtaattata aaaaatagcc agtctttata aactgtattc acgtattcaa
     3061 atcgtatata tagtcgattt attaaatctt tagataaact gtaaaaagtg gtttccatag
     3121 ccactttttg ctataataga ggcagtaaaa atgaaggagt cggctatgga acactcgtct
     3181 tggcatgctt tgattaaggc gcaattacct gagggttatt tcgggaaaat caatcagttt
     3241 atggagcagg tctattctca ggggattatt tatccaccca aggaaaaggt ttttcaggct
     3301 ctcttgacaa cactgcttga agaagttaag gtggtaattc tagggcaaga cccctatcac
     3361 ggaccaggtc aagcgcaggg cttgagtttt tctgtacctg actctatccc agctccacca
     3421 tccttgcaaa atatcttgaa agaattgtca gatgatatcg gagttaagaa atctcatgat
     3481 ttgacagctt gggctgagca aggagtcttg cttcttaatg cttgtttgac tgttcctgct
     3541 ggacaggcca atggtcatgc tggtcaaatc tgggagcctt ttactgatgc tgtgattcag
     3601 gtggtcaatc atctagatag accagtcgtt tttgtactct ggggagctta tgcacgtaag
     3661 aagaaggcat tagttaccaa tcctcatcac ttgattatcg aatcagccca tccaagtcct
     3721 ttgtcggttt atagaggatt ttggggttcc aagccctttt ccaaggccaa tgcattctta
     3781 aaagagacag gacaagagcc aatcgattgg cttagataag gagaaaatat gcctcagtta
     3841 gcgacgattt gctacattga taatgggaaa gaactgctca tgctccatcg taataagaaa
     3901 cccaatgatg tccatgaagg gaaatggatt ggtgtgggtg gtaagctaga gagaggagag
     3961 acgccccagg aatgcgcggc gcgtgaaatc cttgaagaaa cagggctcaa agccaagcca
     4021 gttctaaaag gtgtcatcac ttttcctgaa tttacaccag atttagactg gtacacctat
     4081 gtttttaagg tgacggagtt tgagggcgac ttgattgact gcaatgaggg gacgctagaa
     4141 tgggttccct atgatgaggt tttgagcaag ccgacttggg aaggtgacca cacctttgtt
     4201 gagtggcttt tagaggataa acccttcttt tcagccaagt ttgtttatga tggggataaa
     4261 ttgttggata cccaagttga tttctatgaa taaaggagaa agcagatgct actaatcaaa
     4321 aatggtcgtg taatggatcc caagtctggt ttggatcaag tttgtgatgt cttagttcaa
     4381 gatgggaaaa ttatcaaaat tgcgcctgag atcacggaag aaggagcaga aacgattgat
     4441 gctactggtc ttgtggttgc tcctggtttg gtcgatattc atgtgcattt ccgtgaacct
     4501 ggtcaaacac ataaagaaga cattcatact ggtgccctgg cagccgctgc aggtggtttt
     4561 actactgtcg tcatgatggc taataccagt ccaaccattt cagacgtgga gactttgcaa
     4621 gcagttctcc agtcagctgc caaagagaag attaatgtca agacagttgc gaccattact
     4681 aaaaacttta atggtaaaaa cttgactgac tttaaggcgc tcttagaagc tggtgcggct
     4741 ggtttctctg atgacggtat tccgcttgag agcagtaaga ttgtcaagga agccatggag
     4801 gaagccaaaa aactcaatac ctttatcagc cttcatgagg aagatccagg tttgaacggt
     4861 gttcttggct ttaatgaaaa tattgctaga gaacatttcc atatctgcgg tgctactggg
     4921 gtggctgagt acgctatgat ggcgcgtgat gtcatgattg cctatgcaac taaagcccat
     4981 gttcacatcc agcatttgtc taaggaagaa agtgttaaag tagtggagtt tgctcagggg
     5041 ttaggtgcag aagtcacagc agaagtagcg ccacagcatt tctctaagac agaagcactt
     5101 tttttaacac aaggtagcaa tgctaagatg aatccaccgc ttcgtttgga atcagaccgt
     5161 cgtgccgtta tcgaaggtct caaatcaggt gtcatcacag ttattgcgac tgaccacgcg
     5221 cctcatcatg tagatgaaaa aaatgttgag gatattacca aagcgccatc tggtatgact
     5281 ggcttagaaa catccctgtc tctcagcttg acctatttag tagaagctgg tgagttgagc
     5341 ttgatggaat tacttgaaaa aatgacatac aacccagcca agctttacaa ctttgaagca
     5401 ggttacttgg ctgagaatgg tccagcagat atcactattt ttgatgccaa ggctgaccgc
     5461 cttgtggact cccattttgc ttccaaagca gctaattcac cattcatcgg tgaaacctta
     5521 aaagggcagg ttaaatatac catctgtaag ggacaaatcg tctatcaagc ttgataggag
     5581 ttagaatatg aattattttc gaaaacgtag ggagagacaa gcgaaatcta atagtggaat
     5641 ttactgtccc gcagctaatc gttccaaaat tcaatatgaa actaaagaaa aagctgacca
     5701 tgcggttcaa tatgataacg gaggtttagt tagaagctat tattgtcgta catgtgcgtg
     5761 ttggcatact acttcaaaat ctaataaacc tccgctaagt ttgaaaaact atggtctgaa
     5821 actctttggt ttagataaat cagaatagaa agagaagtat gtataagaca aagtgtttac
     5881 gagagaagtt agtattattt ttaaaaattt tcttcccaat cctgatttac caatttgcca
     5941 attattctgc ctcttttgtt gatactgcaa tgacaggtca atacaacact atggacttgg
     6001 ctggtgtatc tatggcaacc agtatctgga atcctttctt tacatttcta acagggattg
     6061 tgtcagcctt ggtgcctatc attggtcacc atcttggtcg aggaaaaaag gaagaagttg
     6121 cgtctgattt ttaccaattt atttatttgg ccttgggcct atctgtggta ttgctgggga
     6181 tggtactttt cttggcacca acaatcttga atcatattgg gttagaagca gcagtagcgg
     6241 cagtagcggt tcgctatctt tggtttttat ctatcgggat tatccccttg ttgctcttta
     6301 gcgtcattcg ttccttgctg gattcgctgg gcttgaccaa actgtccatg tacctcatgc
     6361 ttttgttact ccctctcaat agcggattta actatctctt gatttacggt gcctttggtg
     6421 ttccagaact gggaggggct ggtgctggtt taggaacatc cttggcctac tgggtcttgc
     6481 ttgggatttc tgttctggtt ttatttaaac aggagaagct caaagcctta caccttgaga
     6541 aacgaattcc acttaatatg gataaaatta aggaaggagt tcgtttaggt ctgcctattg
     6601 ggggaactgt cttcgcggaa gtggctatct tttcagtggt tggcttgatt atggctaagt
     6661 tttcgtcctt gattatagct agtcaccagt cagctatgaa cttttcaagt cttatgtacg
     6721 cctttcctat gagtatctca tcggctatgg ctattgtcgt ttcctatgaa gtgggagcca
     6781 agcgatttga tgatgcgaaa acctatattg gtctaggaag atggactgcc ctcatttttg
     6841 cggccttcac cttaaccttc ctttacattt ttaggggaaa tgtggccagt ctttatggta
     6901 acgacccaaa atttatcgat ttgacagtgc gttttttaac ttatagtctt ttcttccagt
     6961 tagcagatac ctttgcggcg ccgcttcagg gaattttgcg ggggtataag gatacagtta
     7021 ttccttttta ccttggtttg cttggttatt ggggcgtagc aatccctgtg gctacgctat
     7081 ttgattctct aacagatttt ggagcttatt cttactggat cggcttgatt attagtttga
     7141 ttgtgagtgg ggcgctctac cgttggcgtt taactgtgat tatgaagaga tttgaatctt
     7201 tagcaaaatc caaacgctaa aaagtttgtg aaaaaatatt cttgataaga aaatcccttg
     7261 ttttcacggg gttttctttt ttattttgtg aaatttcttt tagaaaaact ttgacagtat
     7321 ttgccaaaaa cggtaaaata gtaaggtaag aagaaagtta gaaaggcaag aagatgtcaa
     7381 ctttagataa aaatcttttg ctagaaatgt tccgtaagat ggaagaaatc cgtcgcatgg
     7441 acttaaaaat tgcacaatta gtaaagaaag ggaaagtgcc aggaatgacg cacttttctg
     7501 ttggtgaaga ggcagctaac gtgggggcta tgttagctct caatccagat gatctgatta
     7561 cctcaaacca ccgtggacac gggcaagcta ttgctaaagg gattgacctc aacggaatga
     7621 tggctgaaat ccttggtaaa tacactggaa cctgtaaagg gaaaggtgga tctatgcata
     7681 tcgctgacct tgatgctggg aaccttggtg ccaatggtat tgtaggtggt ggtatgggga
     7741 tcgctgtcgg tgcagccctc agtcagcaaa tgcaaaatac cggtaaaatc gttgtctgct
     7801 tctttggaga tggtgcgacc aatgaaggtg ttttccacga agcagtgaac atggcttcta
     7861 tctggaacct gccagtcatt ttctattgca ttaacaacgg ttacggtatc tctgcggata
     7921 tcaagaaaat gaccaatata gaacatatcc atcaacgtag cgccgcttat ggaattcctg
     7981 gaatgttcat cgaagatggt aacaatgtca tcgatgtcta tgaaggattt cagaaagctg
     8041 tggaccatgt tcgcagtggc aatggtccag tcttgattga aagtgtaact tatcgctggc
     8101 tcggtcactc atcatctgac cctggtaaat atcgtacgcg tgaagaagtg gaattgtgga
     8161 aacaaaaaga tccaatcgaa aacctccgca attaccttat tgaaaataac attgcaagtg
     8221 ccgaagaatt ggaagaaatc caagcgcaag taaaggaagc agtagaagct tctgttaaat
     8281 ttgcagagga aagcccattc ccaccgcttg aatcagcctt tgaagatatt tacgcagact
     8341 aaggagaaag agataaaatg gaaacaaaaa caatgtcctt ccgtgacacc attatccttg
     8401 ctatgtctga ggaaatgcgt cgcgatgaaa atgtgttctt gatgggagaa gacgtcggtg
     8461 tcttcggagg agacttcggt acttctgttg gaatgcttga agaatttggt ccagaacgcg
     8521 tccgtgactg tccgatttct gaagctgcca tctctggagc agcagcagga gctgccatga
     8581 caggacttcg tccaatcgtc gatatgacct tcatggactt ctctgttatt gccatggaca
     8641 atatcgtcaa ccaagctgct aaaacacgtt acatgtttgg tggtaaaggt caggttccaa
     8701 tgactgttcg ttgtgcagct ggtaacggag ttggctctgc cgcccagcac tcacaatctc
     8761 tagagtcttg gtttactcac attccaggac ttaaggttgt ggcacctgga acacctgcgg
     8821 acatgaaagg cctgcttaag tcttctatcc gtgataaaaa cccagttatt atacttgagt
     8881 acaagtcaga atttaaccaa aaaggggaag tgccagttga tccagactac acaattccac
     8941 ttggggttgg tgaaatcaaa cgccaaggaa cggatgtaac agttgttact tatggaaaaa
     9001 tgcttcgccg tgtggttcaa gctgctgaag aattagcaga agaaggaatt tcagttgaaa
     9061 ttgttgaccc acgtaccctt gttccgcttg ataaggatat catcataaac tcagtgaaga
     9121 agactggtaa ggttgttctg gtcaacgatg cccacaaaac aagtggctat atcggtgaaa
     9181 tttcagctat tatttcagaa tcagaagcat ttgactatct agatgcacca attcgccgtt
     9241 gtgcaggaga agatgtgccg atgccttatg cacaaaacct agaaaatgca atgattccaa
     9301 cagttgaaag tatcaaagat gcaatccgaa aaacttataa caaagaatag agttacataa
     9361 gataagttat gtaaataaaa taaagctgac gagaaacttt gtatctttta ggtgcagagc
     9421 tcttcgtcat taatatctta gattagagca cgggctaaaa gctcggaaaa aagataaatc
     9481 tccttggctt catcgaagcc atcgtcgatt tcctattttt cagtcgcttt tgacgccctt
     9541 tgtatcataa atagaattgg agaggtcatg gctgatgaca agctaagagc gactcctgca
     9601 gctagaaagt tagcggatga tttagggata aacctctacg acgtttctgg ctcaggtgca
     9661 aacggtcgtg tccacaaaga agacgtggaa acttataaag acacaaacgt ggttcgcatt
     9721 tcgccacttg caaaacgaat tgccctcgaa cataacattg cttggcagga aatccaagga
     9781 accggtcatc gtggtaaaat catgaagaag gatgttttgg ccctgcttcc tgaaaatatc
     9841 gaaaacgata gcatcaaatc tcctgctcag attgaaaaag tggaagaagt ccctgataac
     9901 gtaacaccat atggtgaaat cgagcgtatt ccaatgacac caatgcgtaa ggttattgcc
     9961 caacgcatgg ttgaatctta cttgactgcg ccaaccttca ccctcaacta tgaagttgat
    10021 atgactgaaa tgttggctct tcgtaagagg gttcttgagc caatcatgga agcaactggg
    10081 aagaagacta ctgtaacaga ccttctttca cttgcagttg ttaagactct tatgaaacat
    10141 ccatacatca acgcttcatt gacagaagat ggcaagacta ttatcactca caactatgtc
    10201 aatcttgcca tggcagttgg gatggataat ggattgatga cacctgttgt ttacaatgct
    10261 gagaagatga gtctttcaga actggttgta gcctttaagg atgttattgg ccgtaccttg
    10321 gatggtaaat tggctccaag tgagttacaa aattcaacat tcacaatcag taatttggga
    10381 atgtttggtg ttcagtcctt tggtccgatt attaaccaac ccaactcagc tatccttggt
    10441 gtcagttcga caatcgagaa gccagttgtc gtcaatggtg aaattgtgat tcgcccaatc
    10501 atgagtttag gattaactat tgaccaccgt gtcgtagatg gtatggctgg tgctaagttt
    10561 atgaaggact tgaaagagtt gattgaaacc ccaatctcaa tgttgattta agagcaagag
    10621 tattcatttt taagatatag ataaaggaag gaagacatgg ccttagaagt aattatgcca
    10681 aaagccggcg tggatatgac agaaggacaa atcgtccaat ggaataaaaa agtcggagaa
    10741 tttgtaaaag aaggagaaat ccttttggaa atcatgactg ataaagtcag catggaattg
    10801 gaatccgaag aagatgggta cttgattgcc attctcaaag gagagggtga aactgtccct
    10861 gtaacggaag ttatcggtta ccttggtgaa gaaagggaaa acatcccaac agctggagca
    10921 gcatcgccag aagctagccc tgtacctgta gcaagtacct caaacgatga tggtaagagc
    10981 gatgatgctt ttgatatcgt tgtgattggt ggaggtcctg ctggttatgt tgcagccatt
    11041 aaagctgccc aactcggcgg taaggttgcc cttgttgaga aatctgaact tggtggaacc
    11101 tgcttaaacc gtggatgtat tccaaccaag acctaccttc ataacgctga aattattgaa
    11161 aatatcggtc atgctgcaaa tcgtggtatc gtgattgaaa atcctaactt cactgttgat
    11221 atggaaaaac ttttagaaac taaatctaaa gttgttaata ctcttgttgg tggtgttgca
    11281 ggacttcttc gtagctacgg agttactgtt cataaaggaa ttggtacaat cactaaagac
    11341 aagaacgtct tggtaaatgg ttctgaattg cttgaaacca agaaaatcat tcttgctggt
    11401 ggttcaaaag tcagcaagat caacgtccct ggtatggaat cttcacttgt catgactagt
    11461 gatgacattc ttgaaatgaa cgaagtgcca gaaagccttg ttatcatcgg tggtggagtt
    11521 gtcggtatcg aactcggtca ggccttcatg acatttggtt caaaagtgac tgttatcgaa
    11581 atgatggacc gtatagttcc agctatggat gcggaagttt ctaagaacct tcgcttgatc
    11641 cttgagcgta aaggaatgac catcttgact ggtactaaac tgcaagaaat cattgaggaa
    11701 aatggtcaac ttcgtatcaa ggttgaagga aaagacgata tcatcgcaag caaagctctt
    11761 ctttcaattg gtcgtatgcc agaccttgaa ggtattggag aggttgagtt tgaattggat
    11821 cgtggttgta tcaaggtcaa cgaatacatg gaaacttcag ttccaggcat ttatgcacca
    11881 ggtgacatca acggtactaa gatgttggct cacgcagctt tccgcatggg tgaagtttcc
    11941 gctgaaaatg cccttaaagg aaatcatgca gttgccaaat tgaatttgac tcctgcagcc
    12001 atctacactc tccctgaagt agcagcagta ggtttgacag aagaacaagc ccgtgagaaa
    12061 tacgatgttg ccatcggtaa gtttaacttt gctgctaacg gtcgtgctat tgcatctgac
    12121 gctgctcaag gtttcgtaaa agttatcact gataagaaat acggagaaat ccttggtgta
    12181 cacattattg gtcctgcagc cgcagaatta ataaacgaag catcaagcat catcgaaatg
    12241 gaaatcactg ttgaggaaat gctgaagacc atccacgggc acccaactta ctctgaagtg
    12301 atgtacgaag cgtttgcaga tgttctagga atggccatcc attcacctaa gaaaaaataa
    12361 aacaaagata gattagactg gaaggttatt tccagtttct atcatataaa gtaaagggat
    12421 atcatgaaat acattatcaa tcattcaaat gacactgctt ttaatattgc cttggaagaa
    12481 tacgccttta aacacctttt ggatgaggat caaatcttcc tactttggat taacaagcca
    12541 tctatcattg ttggtcgtca ccagaacact atcgaagaaa tcaaccgtga ttatgttcgc
    12601 gaaaatggta ttgaggtagt tcgccgtatt agtggtggtg gagctgttta ccacgattta
    12661 aataacctca actacacgat catctccaaa gaagatgaaa ataaggcatt tgacttcaag
    12721 agcttctcaa ctccggttat caataccctg gctcaacttg gggttaaagc tgagttcaca
    12781 ggtcgtaatg accttgagat tgatggtaag aagttctgtg gcaatgccca agcctatatc
    12841 aacggccgta tcatgcacca cggttgcttg ctctttgacg ttgatttgtc agtcctcgca
    12901 aatgccctta aggtttcaaa agataaattt gaatcaaaag gtgtgaaatc cgtccgtgcc
    12961 cgtgtaacca atattatcaa tgaattacca aaaaaaatca cagtcgaaaa attccgtgat
    13021 ttactcttgg aatacatgaa aaaagagtac ccagagatga ctgaatacgt cttttcagaa
    13081 gaagaattgg ccgaaatcaa tcgcatcaag gatactaagt ttggaacttg ggactggaac
    13141 tatggtaaat cacctgaatt taacgtccgt cgtggaacca aattcactag tggtaaggtt
    13201 gaagtctttg ctaacgttac tgaatcaaaa atccaagaca tcaagattta tggtgacttc
    13261 tttggtattg aagacgttgc tgcagtagaa gatgtccttc gtggggtgaa atacgaacgc
    13321 gaagatgttc ttaaggcgct aaaaaccatt gatatcacac gctacttcgc tggtattagc
    13381 cgtgaagaaa tcgctgaagc ggtagttgga taaatcaaaa agaagttggc caactaacca
    13441 acttcttttt ttgatattta tttacataat ttaaaatacg taaaatcata aactatccag
    13501 agcattcttt tgttcatcat taacaatatg ggtatagagg tcagtgactt gtgtgctggc
    13561 atgtcctagt tggtgactga ctaaaacttg tgatttagta gcatcataga gcctagttgc
    13621 tagtgtatgg cgcagtttat ggggtgttac acgtacttta aaatcctctg agtatttagc
    13681 aaccattttc tcaacgctag aagcatcgat acgattagga acacctctgt agagagttaa
    13741 aaaaagggct gtatctgttt tttccgtttt atagcgttga ttccgaatgg ccagataatt
    13801 ctctaaataa ggtttagcaa aagcagcgac attgactgag tcacgtttgc caccttttcg
    13861 agtaacatca ataaccatca tttttagatt gagatctctt agatctagat taatagcttc
    13921 agataagcga acaccagatg ccaagagaag ggcaataatg gctaaatctc gttctttatt
    13981 tttgttgaat gatgagagag ctcgatttga aagctgttgt gggtgctctt gatcgatata
    14041 agttagaaaa ccttctgttt catcacctag aaagagtttt tgcttgatat tttcagctct
    14101 ggcagcaagg gtttctttct ttttcttggt tgaaactttt ttcattacat tacgatagaa
    14161 ataaggttcc ccctgatcgt tttcaacctc ctcggttaga tacttgtaaa gactagaaag
    14221 tgctgataag gttcgattga tagttgtctg tgaaacacct tgttttgttg tattagcatt
    14281 cagcaaggga cgttcacgta gataaaggat aaaggattcc atgtctttct tagacatatt
    14341 ttccaaaact gataaaggaa tatcggatat tttatcagcg tttgaaatac cagactccaa
    14401 aacccagctg aaaaatcggt catattcctt aaggtattcg tacagggttg taaaactgta
    14461 gggcacagcc agtttagatt ggtagtattc cagaacatac cagggcatga gttgttttag
    14521 tttgttgatt cgttccagta aaatctcacg tttcatgtat tttctccata agtaagtata
    14581 ctagtagtat agcatagact tgtatatttt tcaagaaaat tatagttttt cagaaagatg
    14641 ttataggagt ttttcaaagt gataaaaaga cttagaccta caaacaaaac agaataagga
    14701 aaataatgaa aatctcaccc actaaacttc tgttaatact acataactga agagctatat
    14761 aaggagctat gagatacaaa acacattgta taatagattg aaactagaat agtacatctg
    14821 gacttctaaa acattgctag aaattgattt gattgtcctg tttgttttat cctatttcta
    14881 tttcatttca ctataattac tattgttttc tttttcatga ttttaatctt actgtacaga
    14941 tttgatacag taaactcctt tcta
//
LOCUS       DBEJKC010000045        14785 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.045, whole genome shotgun sequence.
ACCESSION   DBEJKC010000045 DBEJKC010000000
VERSION     DBEJKC010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14785
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.045"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(385..777)
                     /gene="rpsI"
                     /locus_tag="ACL3G6_001522"
     CDS             complement(385..777)
                     /gene="rpsI"
                     /locus_tag="ACL3G6_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HGR0546026.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(797..1243)
                     /gene="rplM"
                     /locus_tag="ACL3G6_001523"
     CDS             complement(797..1243)
                     /gene="rplM"
                     /locus_tag="ACL3G6_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HGR0546027.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            1599..1916
                     /locus_tag="ACL3G6_001524"
     CDS             1599..1916
                     /locus_tag="ACL3G6_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HGR0546028.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(1961..2773)
                     /gene="folK"
                     /locus_tag="ACL3G6_001525"
     CDS             complement(1961..2773)
                     /gene="folK"
                     /locus_tag="ACL3G6_001525"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HGR0546029.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIEKMRNRGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(2816..3370)
                     /gene="folE"
                     /locus_tag="ACL3G6_001526"
     CDS             complement(2816..3370)
                     /gene="folE"
                     /locus_tag="ACL3G6_001526"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HGR0546030.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(3351..4673)
                     /locus_tag="ACL3G6_001527"
     CDS             complement(3351..4673)
                     /locus_tag="ACL3G6_001527"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGR0546031.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGMFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNVTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(4675..5649)
                     /gene="folP"
                     /locus_tag="ACL3G6_001528"
     CDS             complement(4675..5649)
                     /gene="folP"
                     /locus_tag="ACL3G6_001528"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HGR0546032.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGADLVNDITGLMGDEKMAHVVAEARAQVAIMFNPVMARPQHPSSLI
                     FPHFGFGQAFTEEELADFETLPIEELMEAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(5744..6451)
                     /locus_tag="ACL3G6_001529"
     CDS             complement(5744..6451)
                     /locus_tag="ACL3G6_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0546033.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLVLFIMGARKTKLASFNFSFFRAKDLARLVLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIIPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(6505..7923)
                     /locus_tag="ACL3G6_001530"
     CDS             complement(6505..7923)
                     /locus_tag="ACL3G6_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGR0546034.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHVMIWILDALFILNYISMAL"
     gene            8113..8925
                     /locus_tag="ACL3G6_001531"
     CDS             8113..8925
                     /locus_tag="ACL3G6_001531"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0546035.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            9264..10283
                     /gene="adhP"
                     /locus_tag="ACL3G6_001532"
     CDS             9264..10283
                     /gene="adhP"
                     /locus_tag="ACL3G6_001532"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HGR0546036.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            10516..11505
                     /locus_tag="ACL3G6_001533"
     CDS             10516..11505
                     /locus_tag="ACL3G6_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0546037.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQAAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            11533..12336
                     /locus_tag="ACL3G6_001534"
     CDS             11533..12336
                     /locus_tag="ACL3G6_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HGR0546038.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            12360..13271
                     /locus_tag="ACL3G6_001535"
     CDS             12360..13271
                     /locus_tag="ACL3G6_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0546039.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(13327..14661)
                     /gene="pepC"
                     /locus_tag="ACL3G6_001536"
     CDS             complement(13327..14661)
                     /gene="pepC"
                     /locus_tag="ACL3G6_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HGR0546040.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
BASE COUNT         4276 a         3293 c         2923 g         4293 t
ORIGIN      
        1 cttccccatt ctatggaatc ttgcattatc cataatatag tagattgaaa ctagaatagt
       61 acacctctac ttctaaaaca ttgttagaat tcgatttgac tatcctcgat ttgtcctatt
      121 cttatttcat attactataa aaataaggta aacttttcaa aaaagcacga aaaaagcacc
      181 catagggcaa acctttgagt gctttgaaac attgatataa tcgtattgat taacgttttg
      241 aggcaactga ccttgtcagg ttgcagccac atttgtaagc gactaaagtc gcaacaactg
      301 tgtcaattgc accaatttag taagaaagta taaaaaaaga acaccccgaa aggtgctctg
      361 tataagtata gtaattcttt cgaattaacg tttactaaat tgtgatgctt tacgagcttt
      421 cttaagacct ggtttcttac gttcaacttt acgtgagtca cgtgtaagaa gtcctgcgcg
      481 tttcaatgaa tcgcggaagt ctgggtctac ttgaagaagg gcacgagcga taccgtgacg
      541 gatagctcct gattgaccag cgtatccacc acctacaacg ttaacgaaaa cgtcgtatga
      601 acctacagtt gaagtaactg cgaatggttg gttgatgaca agacgaaggt cagcgtgtgg
      661 gatatactct tcaacatctt ttttgttaac agtgatttta ccagttcctg gaacaaggcg
      721 aacgcgtgca acagcgtttt tacgacgtcc agtacctgca tattgtgctt gtgacatact
      781 ttatttgttc ctttccttag ataagtcctg aaatgtcaag aacttctggt tgttgtgcag
      841 catgagtgtg ctcagctcca acaaatactt tcaacttcat accttgagcg cgtccaagtg
      901 tattgtgtgg aagcatacct ttaactgatt tctcaatcaa acgtactgca tttttagaac
      961 gaagttcacc tgcagagatt tgtttcaatc cacctgggtg gtttgagtga gtgtagtaga
     1021 ttttatcagt tgctttttta ccagtcaatt taactttttc agcattgata acaatcacga
     1081 agtcacctgt atcagtgtgt ggtgtaaatg ttggtttgtt ttttccgcga agtacgctag
     1141 caactactgc agaaagacgt ccaagtggta catcagttgc gtcaactacg taccatttac
     1201 gttcaacttg gcctggttta gccataaatg ttgttttgtt catgatttct cctatatata
     1261 gttcgatttt tgtttacggt gatgggtgtt ccttcccatc gaaaagtatt tggaaggttc
     1321 cggggccttt caaatggggt aaacaatacc gcctactatc ataccaaatt tcacccctaa
     1381 aagtcaatag atataaaaaa tatttttcgg taacttctca aaataactga aagttatata
     1441 atcaagttaa tttgggaatt tacctattaa cttcggtaga tttttgggaa ttttttccct
     1501 atttctccct gtaactaaaa tccttttcaa aaaatcacct tttcttgatt tttaatccta
     1561 tttgctgtat gataagggaa aagaaagggg acagagatat ggcttttacc aatacccaca
     1621 tgcggtctgc tagttttggc attgttacca gcttgcccga tgacatcatt gactcttttt
     1681 ggtatatcat cgatcatttc ttaaaaaatg tctttgaatt ggaagaagaa ctcgagtttc
     1741 aattgcttaa taaccaagga aagattacct tccacttttc aagtcaacac ctccctacag
     1801 ccattgattt tgactttaac catcctttcg accctcgtta tcccccaaga gtactggttt
     1861 tagacatgga cggtagagaa actatcctcc tcccagaaga aaatgaccta ttttaaaaac
     1921 tctagccttc agttgcaagt aactgaaaac tagagttttt ctattttttc aaagcatcat
     1981 acaagttgcg gatcggttgt tttaatatcg gatggataaa atgaggcgca atttcctgta
     2041 aggactcaag gacaaaaagg cgttccgcta tgtaaggatg aggcaatatg aggtcgtctg
     2101 tataaaggat ctggtcctcc acaaagagca agtccaaatc aatcaaacga ggtccccaat
     2161 gcacttctct cacccgtccc agctctgact caatggctaa caaggtttct aacaagtctt
     2221 gtgctggtag ccaggtttcc acctcaacca cttgattggc aaagctatcc tgctccactc
     2281 caccccaagg ctccgtcgct aagacactgg actctttgag aatatggata cctcgatttc
     2341 gcattttctc aatggcttgt ttcaagtttg cttgtttatc tcccatattg cttcctaggg
     2401 cgataaaggc tcgttgcttg cggcgatgga tggttaccga gcaagtatct agtgacaaat
     2461 gcaccggtgc ccaaggtttt ttcagttcca acttcatttc ttggacaaga ggataagact
     2521 caaaggtacg ttccaccagt ttataggcta ccgtttcaat caaatcttca ctcgtttcct
     2581 gaaaccaagt cgtccactgc tgacacaatt ctccgtaatg gacagaggct gttaaatcca
     2641 agtctgtagc tgccttggtc atatcatagg ataggatggc tgaaacgaca aatttctgcc
     2701 ccaattcttt ctcactagga aaaagaccat gataggcaaa catttccaaa tccttaatct
     2761 gcagttgatc cataatgatt cctttctaga aaaatccgct tgaagcggat tctttttata
     2821 gccccattaa acgataagct tggtcgcgga ggtccttatc tgtttcaaat agaccacgag
     2881 ctactgtcgt caaggttgca gtgcctggtt ttctaacacc acgcatactc atacacatat
     2941 gttccgcctc aatgacaaca aaggctcctt tagcacctag atagtccatc aaggcatcgg
     3001 ccacttcgat attcaaacgt tcttgaattt gtggtttttt cgaataaact tcaaccgtac
     3061 gggctagctt agacaagcct gccacacgac catctggaat gtaggcaatg tgcgctctac
     3121 cataaaatgg caagaagtgg tgttcacaca tggtatggaa aaagatatcc ttttctacca
     3181 ccatattatc gtcaataatt tcaaaggatt ttgacaaatg ttcctctgct gtttgaccaa
     3241 gacctgaaaa aatctcttga tacatacggg ctacacgagc aggtgtttcc tgcaagccct
     3301 cgcgattagc gttctctcct acagcctcga taatcatttt tacagctgct tcaatctttt
     3361 gtgtatccat tctcgttctt cctctccatc agataggccc tcacttggct caagaaatac
     3421 aaggaacctg tgacaatcct aactgtttgt ttctcttctt ttttatctgt cacattctgc
     3481 tctagaaaat catgccaatc ttggtagctg agatttctag acttagctgc ctctttcagc
     3541 acgctttcat ccgtcgcccg actatccgca aaatgtgtta gagtaagctc ggtatctggc
     3601 atggctccca gcaagtccaa catatcctcc aaggctttgg ttttgataca agtgaagagg
     3661 atttccttat gataatccgc aaaacgttct tgcaaggtta ccaacaaggc cttgatagca
     3721 tggggattat gggctccatc caaaatcatc aagggatctc ttgacacgat ttccaaacgc
     3781 cctggccaac ttgtttcttc caaggcttga ccaagaaagt cattgcttgc tagctctcga
     3841 ccatcttctt gacaaaaagt atcaagtaaa gctatggcca tcccagcatt ctctatttgg
     3901 tacaaaccaa gcaggctagt ctggaagcga ccttgtctga cagcacttgt atagtcaaag
     3961 acttcccctg tcaccacact ttcttgatga cgaacctgat aatctgtccc gtaggcaagt
     4021 ctcggcgcat ctttcccttc cgcaatgcgg tcaatcacag tcaaggcttc tggagcaata
     4081 cgccctgtta ccaagggcat cccttgtttg ataatacctg ccttctgctc tgctatggcc
     4141 tccaaggtgt caccaagtag ggccacatga tccaagccaa tagttgtaat tcctgtcaaa
     4201 atgggctgac agacattggt actatccaaa agtccaccca tgccaacttc catgatggcc
     4261 acatctactt gctctgaggc aaagtagtca taggccaggg ctgtgataat ctcaaactcg
     4321 gttgtgccct gtaaattggc gaccgcttct ccctccagca aagactgata gtctgccatg
     4381 agagcttcta gcctcgcttc tgagatcgat tccccattga tgctaatctg gtctgtgtaa
     4441 tgaatgagat agggcgagct aaacatgcca actctcagcc ctagcttttc tagcatcttt
     4501 ttcaaaaaag caatagtcga gcccttgccg ttagttcctc cgatatggag gaccttgagt
     4561 ttgagatggg gattgccacg caaagctaac agttccacca ttcgttccaa gccaaaatgc
     4621 ggttgatccg tccggtagtt agcaatccac tgattgtttt caatttcttt catcttattt
     4681 atattgtttt aaatctaaat tttccgcttc atcagccaga cgaatggcag aggcaatttc
     4741 aactgccatc ctgtgactag ctacgtcatg cacgcgcacc acttctacac cctgtctcgc
     4801 agcgatacta gttacatgag ccgaagccgt gtcccgattt cggaaaccaa gctctgtctc
     4861 aggattgact tcaaaaccat tctcctctag gatattgatg acaaatcgct tgcgcgacac
     4921 tccgagaaag attggatagc ccttctgatg tagtttatcc aggtcccgta aaagaagcag
     4981 attttctttc ttggtcagac caaagccaat tcctggatcc aacaggatat tttctggtgc
     5041 aataccagct tctgccgctc tcgctagtgc tcgttcaaag aaagcctcca tcaattcttc
     5101 gattggcaat gtttcaaagt cagctaactc ttcctctgta aaagcttgac caaaaccaaa
     5161 atgagggaag atgagcgagc tagggtgctg aggtcgcgcc ataactgggt taaacatgat
     5221 ggccacttgc gctctcgctt cagctaccac atgagccatt ttctcatcac ccataagacc
     5281 agtgatatca ttgactagat cggcaccagc agccaaagca gcctctgcta cttgactctt
     5341 ccaagtatca atagagatga ggacatcact ttccttgcga atcgctttga tcactggaac
     5401 aacacgctgg atttcctctt ctatctcaac atagctactg cccggccgag tcgattctcc
     5461 gccgatatcg agcatactgg ctccttcggc tatcaattta cgagcctgct ggagtgcctg
     5521 ctcaagagca aaaaattgac caccgtccga aaaggagtct ggggttacat tgataattcc
     5581 gcaaataact gtctttgcat gattggcttt acttgacata tcggtcactc cctcaaggat
     5641 tttcatcata ttatttttct attttaccat aaaaagaaaa agatggacac gattgcattc
     5701 atctttccct agtagaaaga ggtcggttcc tacataaaaa cttttacaca gaaattccta
     5761 atgtccgact cataatcacc acaagagcca acaaacagaa agcaatccca ttaacaatca
     5821 tgtgaagcaa gatcgacatt tccaaacgtt gggtcttgta ggctgtccaa gatagaactg
     5881 tcgacatacc tccataaatc aataaagaag gtaaattact tggttgatgc aataaagcaa
     5941 acacaatcgt accgactaca aatcccaagt tctccttgcc tcggaaaatc tttttaggaa
     6001 taatcccacg acacaagatt tcctcacaaa tcggagcaag caaggctagc aagaagaagc
     6061 tagaaatcaa cgaactattc tgaaccatat cattaatctg agactggtta gctgttgtcg
     6121 tctcatttga cagttgcaac aagatagaac caagtatatt tgacccgaca ataactagat
     6181 aactcaagac caaacgtgcc aaatctttag ctctaaaaaa agaaaaatta aaactagcta
     6241 acttggtttt acgagctccc ataataaata gcaccagaac cacaattgaa aggccagcaa
     6301 ctatcagccc tgactgtagc agggctactt cttttaaagt caaaatagag gtaaccacta
     6361 ggggaacctg atataaaagg acggcaagta aaaagaccaa aatccagcct gcacgattca
     6421 acaattcttt ccacatattt ttctctttca tcacctatct ccttttgtat taaaaaaggg
     6481 gggaaatccc cctgggtcat tctattataa ggccatgctg atgtagttaa ggataaacaa
     6541 ggcatccaaa atccaaatca tgacatgaac atctttaact tgacctttaa caagcttagt
     6601 caaagtgtaa gtcaagaaac caactgcaat cccttgagtg atagagtagc tgaatcccat
     6661 aaagatagat gtgaagaagg caggaactgc ttcagacata tcatcccaat ggatattttt
     6721 caagctacca agcatcataa tcccaacgat aatcaagatt ggagctgtag ccgctgttgg
     6781 tacgatcgct agaagtgggc taaagaagct tgaaatcgca aaacagatag ctacaaccaa
     6841 ggctgtcaaa ccagtacgtc cacctgcacc gataccagca gcagactcaa cataagtcgt
     6901 tacgtttgaa gtacctgcaa tggcaccgac tgtcgttcca atcaaatcag agtaaagagc
     6961 cttatccaat ttggctgatt ggtgattttc accatttgtc gctacgatac caactttttc
     7021 acctgtaccg atcaaggtac caattgtgtc aaaaatatct gtcaatgaga aggcaagaat
     7081 ggccatcaga gtttcaggca agcgagctgt atctgaaacc aaagctccca aaccttctga
     7141 accaagagct gcaccaaaga ttgtcttcaa atcttcaaaa gctgcaccaa catggttatt
     7201 agcaaaatcg atactagaca aatcaaccaa accaactgca atagcaagaa cagttgttgt
     7261 caagatagag agaataattc cccctttaat ccctttgatg acaaagaaga tagtaatggc
     7321 aagtcctgca agagccacta aaacagctgg attattaaag ctgaccaatc ctggaactgc
     7381 tgaagagttt gctgcaatcg ttgcttgagc tttgtcagcc ccttctccta caacagtata
     7441 gttgcctgga tcaatcgtga atttcaaaag tccagcattc ttaatcccta cataggcaag
     7501 gaagacaccg ataccagctg aaatagctga gcgaagagca ttgggaatcg attcaatgat
     7561 cattttacga acatttgtca aggtaataat caatgaaata atcccacaga tgaagaccat
     7621 agctagggct tcttgccaag aataaccaag cccgaataca actgtaaagg taaagaaggc
     7681 attgagtccc atacctggcg cttgggcata aggtaagtta gcataaaaag ccatcatcaa
     7741 ggtacccgct actgcaccaa taatcgtcgc taggaagacg ccctgagcag gcattcctgt
     7801 ttgtgaaagt atttgtgggt ttacaaagag aatatagctc attgcaaaga aagttgttaa
     7861 accagcgaga acctctgtac gaacgtctgt accgttctct tttagtttaa ataatttgtc
     7921 catcatcaat ctccttttaa tttttacgaa caataataga attatatcat ttattattca
     7981 ctttttcaat gtctttgttt gatttgttta agaaattaat ccaatttcat tttttgtttg
     8041 gaatctgctt ttctgcctgc tttctgttat aatagaagac atcttatctg aaaacacact
     8101 agaaaggtcc atatgacgaa aaaaattatt gcagttgacc tggatggaac cctgctcaac
     8161 tcagacagtc aaatttctga ctttaccaaa agaaccatca aaaaagttgc tgaaaaaggc
     8221 catcaggtta ttattacgac aggtcgccct taccgtatgt caaaagattt ttaccgtgaa
     8281 ctgggcttag acactcctat gattaacttc aacggatccc ttactcattt accagaccaa
     8341 gtttgggatt ttgaaaagtg tttgactgta gacaaaaaat atctgctaga tatggttcaa
     8401 cgttcagagg acattcaagc cgattttatc gctggagaat atcgtaaaaa attctacatt
     8461 acaaatccca atgaagaaat tgccaatccc aaactatttg gtgtagaagc tttccagcct
     8521 gaagatcaat tccagcctga attggtgacc aaggacccta actgtatcct cttgcagacc
     8581 agagccagtg acaaatatgc cttggcaaaa gacatgaacg ccttctacca gcatcaactt
     8641 tctatcaata cctggggagg tccgctcaat atccttgaat gtaccccaaa aggtgtcaac
     8701 aaggcctttg ctttggacta cttgctcaag ataatgaatc gtgacaaaaa agatttgatt
     8761 gcctttggag atgaacacaa tgataccgaa atgctcgctt ttgctgggaa gggttatgcc
     8821 atgaaaaatg ccaatccaga gctactccct tatgcagatg agcaaatttc ccttaccaac
     8881 gaccaagatg gggttgccaa aaccctacaa gacttattct tataacctat actgatactc
     8941 aatgagaatc aaagagcaaa ctaggaagct agccgtaggt tgctcaaagc actgctttga
     9001 ggttgtagat gaagctgacg tggtttgaag agattttcga agagtatgac cagcttgcaa
     9061 gctggtcttt gtgctctttt cacagtctca tcaaccagtt aatcgattgt tctacttttt
     9121 gtctccaaaa ccttggaaaa ggctttcttt tgtgatatac ttcacatata aatacaagag
     9181 agctcgtcac actcgactct gttgacaaaa aatcaatcca gtcccgttgt ccctgttctc
     9241 ggtcaatatc aaggaggata gctatgaaag ctgttgttgt aaatccagaa agcactggtg
     9301 ttgctattga agaaaaagta ctccgtccac ttgaaactgg ggaagcactt gtagaagttg
     9361 aatactgtgg cgtttgccac accgacctcc acgttgctca tggtgacttt ggtcaagtcc
     9421 caggacgtgt tcttgggcac gaaggtatcg gtatcgttaa agagattgct ccagatgtga
     9481 aaagccttaa agtcggtgac cgcgtcagcg ttgcttggtt ctttgaagga tgtggcactt
     9541 gcgaatactg tacaactggt cgcgaaaccc tttgccgtac agtgaaaaat gctggctact
     9601 cagtagacgg tggtatggct gaacaatgta tcgtaactgc tgactatgct gtcaaagttc
     9661 ctgacggact tgatccagcc caagcttctt ctatcacatg tgctggagta acaacctata
     9721 aagctatcaa agaagcaaaa gttgaaccag gccaatgggt tgttctttac ggtgctggtg
     9781 gacttggtaa cctcgctgtt caatacgcta aaaaagtatt caatgctcat gttatcgcag
     9841 tcgatatcaa caatgacaaa cttgcccttg caaaagaagt aggcgctgac attgtgatta
     9901 acggcctcga agttgaagat gtagctggac tcattaaaga aaaaactgat ggaggagctc
     9961 attcagctgt cgtaactgct gtgtctaaag ttgccttcaa ccaggctgtt gactccattc
    10021 gtgctggtgg tcgcgtcgtc gctgttggtc ttccttctga aatgatggaa ctcagcatcg
    10081 ttaaaacagt cctcgatgga atccaagtca tcggttctct tgtcggaact cgtaaagact
    10141 tagaagaagc cttccaattt ggtgcagaag gtctggtagt cccagttgtt caaaaacgtc
    10201 cagtagaaga tgctgttgcc attttcgacg aaatggaaaa aggccaaatc caaggacgta
    10261 tggtactcga cttcacccac taatctaata gaaacctatt ttaaaagttg gaagcttctt
    10321 ccaacttttt tatattaaat tttaaataag aattcaagat tactcctcaa aaactcaaca
    10381 tatcaacata caaaaataaa aattttttaa ttttttatga taaatagttg ctttttttat
    10441 gaaaacggtt tatacttaaa cagtcttaaa gttttcttaa atgaaaacta aaacaaaaaa
    10501 ggaggaatga caataatgag tatcggaatc attattgcga gccacggcga atttgctgcg
    10561 ggtattcatc agtcaggatc tatgatcttt ggtgaacaag aaaaggttca agttgtgacc
    10621 tttatgccaa atgaaggtcc tgatgatcta tacgctaagt ttaataacgc tgttgctgca
    10681 tttgacgcag aagatgaggt tctagttttg gctgaccttt ggagtggttc tccatttaac
    10741 caagctagtc gcgtgatggg agaaaatcct gagcgtaagt ttgccatcat cacaggactt
    10801 aacttaccga tgttgattca agcctacaca gagcgcctca tggacgctgc tgcaggtgta
    10861 gaaaaagtcg ctgctaatat cattaaagaa gccaaggatg gcatcaaagc tcttccagaa
    10921 gagctaaatc cagttgaaga agttgcaagc gctgcagctg ctccagttgc ccaagctgct
    10981 atcccagaag gaactgttat cggagacggt aaattgaaaa tcaatcttgc ccgtcttgac
    11041 acacgtctac ttcacggtca ggttgcaact gcttggactc cagattcaaa agcaaatcgt
    11101 atcatcgttg cttcagataa cgtggctaaa gacgaccttc gtaaagaatt gattaaacaa
    11161 gcagctccag gtaatgtcaa ggctaacgtg gttccaattc aaaaactgat tgagatttca
    11221 aaagacccac gttttggaga aacacatgcc cttatcttgt ttgaaacacc tcaagatgcc
    11281 cttcgtgcca tcgaaggcgg cgtgccaatc aagactctta acgttggttc tatggctcac
    11341 tcaacaggta aaacattggt caataccgtt ttgtctatgg acaaagaaga tgttgcgaca
    11401 tttgaaaaaa tgcgtgactt gggtgttgaa tttgatgtcc gtaaagtacc aaatgattct
    11461 aaaaaagatt tgtttgactt gattaacaaa gccaatgtca aataagccat tatttatgaa
    11521 aggattttaa acatgtctat tatttctatg gttttagtag tcgttgtagc cttctttgca
    11581 ggtcttgaag gcatcctcga ccagttccaa tttcaccaac cacttgtagc ctgtaccctt
    11641 attgggcttg taacaggtca cttggaagca gggattatcc tcggtggatc gcttcaaatg
    11701 attgcccttg gttggtcaaa tatcggtgct gctatcgctc ctgatgctgc acttgcttct
    11761 gtcgctgctg ccattatcat ggttcttggt ggtgacttta ccaagactgg tatcggtgtt
    11821 gcccaagcgg ttgctatccc tcttgccgta gctggacttt tcttgacaat gattgttcgt
    11881 acaatttcag ttggtttggt tcatactgca gatgctgccg ctaaaaaagg tgacttcggc
    11941 gctgtggagc gtgcgcattt cattgcgcta ctcttccaag gacttcgtat cgcgcttcct
    12001 gcagctcttc tccttatggt accaactgaa actgtacaaa gtatccttag tgccatgcca
    12061 gactggctca aagatggtat ggctatcggt ggtggtatgg tcgttgccgt tggttacgcc
    12121 atggttatca acatgatggc aactcgtgaa gtatggccat tcttcgctct tggtttcgtt
    12181 ctcgctgctg tgtcagatat tactctaatc ggattcggtg ctatcggtgt tgctatcgct
    12241 cttatctacc ttcacctttc taaaactggt ggaaatggtg gcggaggagc cgcaacttct
    12301 aacgacccaa tcggcgatat cctagaagac tactaagata agaaaggact gaaaacatca
    12361 tgactgaaaa acttcaatta actaaatcag atcgtaaaaa agtttggtgg cgttcaacct
    12421 tcttacaagg gtcttggaac tttgaacgga tgcaaaactt gggctgggct tatacactca
    12481 ttccagctat caaaaaactc tatactaaaa aagaagatca aatcgctgct cttgagcgtc
    12541 accttgagtt cttcaacact catccatacg tagctgctcc agtcatgggg gttactcttg
    12601 cgcttgaaga agaacgtgct aacggtgtgg aaatcgatga cgctgctatc caaggggtca
    12661 aaatcggtat gatgggacct cttgctggta tcggtgaccc agtattctgg tttacagtac
    12721 gcccaatcct tggatctctc ggtgcttcac ttgcccttac tggcaatatc ttgggtccac
    12781 tcctcttctt tgttgcatgg aacttgattc gtatgtcatt cttgtggtat gttcaagaga
    12841 ttggatacaa ggctggatca gaaatcacta aagatatgtc tggtggtatc cttcaagata
    12901 tcactaaagg agcttctatc cttgggatgt tcattcttgc tgtccttgtt caacgctggg
    12961 taaatattaa atttgctttc gatgtttcta aagttcaact agatgaaaag gcttatatcc
    13021 attgggataa attgccagaa gggtctaaag gtatccaaga agcattcgca caagtaggac
    13081 aaggattgtc tcaaactcct gaaaaagtta ctactttcca acaaaacttg gatatgttga
    13141 ttcctggatt atcaggacta ctccttactt tactttgcat gtacttactt aagaaaaaag
    13201 tatctccaat cactattatc cttgccctct tcgcagtggg tattgtggca catgttcttc
    13261 acatcatgta atcaagcaac taaaaaggaa ccaggttcta aaatctgatt ccttttttct
    13321 atgcttttat tcagccaagg ctcccattgg atcccatggt gcaagtacaa ttggttctgc
    13381 tccataggca gcttgttctt ctgctgtcag caattcctta cgaacaacga tttggtatgt
    13441 gtattcgtcc atccaagcgt ctgaggcaac aaagtaacca tctgtaccga ccttgtctcc
    13501 ccatgagttt tcaaccttcc acttggttga tttaccattt tcgtccaagt caacacctgt
    13561 caagaccatg gcgtgggtca tcaagctttc gctatagtcc aaacgtccag ccttgtcttg
    13621 agtaagttta atgtccatgc ttgattcaaa gtcataaaca tctgtcgcaa ggatgccagc
    13681 cttacggtta ctgagctggc cgacatcaga accaaaccaa acagtctcac ctgcttgcat
    13741 ttgggcaatc gccaattctt tcaagcgctc cattggaacg ttgatgtaac gaactgcacg
    13801 gctaccaacc acattcccca acatctcaac tgtgtaagat tttccgtaag gtttatcagc
    13861 agttggagca ttgataacag aaacgtagtc ttctaaagga agattgacat atttcttgta
    13921 aaactcttgt ggtgtgattc ctttttcact tttgtagttg ttatctttat cgcgataagc
    13981 aaagtcaaac ttgcgtggtg gaagtcctaa tgacatagca agaaagttaa agatttcttg
    14041 caagaggtct tctttcttag cttgaacagt cgcttgatct gcaccagaaa caagcaagtc
    14101 acgcaagatt tgagcatctt gacgaagcaa tttattaagg atcgcattta gctcacgact
    14161 gctgctagat gaaacagact caggataaac tgacttaggc acgacaccgt atttttcaaa
    14221 gagggaaacg accatatccc attgaccacc atcttgttga ggtgtttgga gtaagaagct
    14281 aaccttgcgg ctagtcaatt cttggtctga agtcgcaatg acttgctcca agaaccagtt
    14341 tgatttctca tacttatccc agaagaaagt gtgggcttgt gacaactcaa agttctccaa
    14401 tttgtattgc gagatgagtt tgtggcggaa ggtgttgaga gccgcaaaca tccagcaacg
    14461 accagacgct ttctggttag tgaccttgtc cttggttaaa tccaatgaga aaacaggtgt
    14521 gttgtctaca tggctttggc gacgttccag agctgcaaaa attccgttgt ggctagcagc
    14581 attttcaatc gcttggtatt ttacatttgc ttcatagttg gcaaatagtt tatcagtaaa
    14641 tgattcttga atcgcgttca tagattcctc cttttattct acagtctatt ataactcttt
    14701 tcacaaagga agcaactaaa aaacataaaa ggtaaggaca ttctccctca cctttttcga
    14761 atatatactc ttcgaaaatc tcttc
//
LOCUS       DBEJKC010000046        14758 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.046, whole genome shotgun sequence.
ACCESSION   DBEJKC010000046 DBEJKC010000000
VERSION     DBEJKC010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14758
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.046"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..269
                     /locus_tag="ACL3G6_001537"
     CDS             <1..269
                     /locus_tag="ACL3G6_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546041.1"
                     /translation="EMVFAFHLPPDELITNVIFKEKINSMLKCYIDRLLYVFINPTHF
                     TEKVNLQFYGSFFSYEFICREVGNILKNKGVKCNLNFFEGEEYL"
     gene            377..1378
                     /locus_tag="ACL3G6_001538"
     CDS             377..1378
                     /locus_tag="ACL3G6_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0546042.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            1983..2189
                     /locus_tag="ACL3G6_001539"
     CDS             1983..2189
                     /locus_tag="ACL3G6_001539"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546043.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NHTYGKATLTRFEEIFEEYKGVPR"
     gene            2561..3922
                     /gene="trpE"
                     /locus_tag="ACL3G6_001540"
     CDS             2561..3922
                     /gene="trpE"
                     /locus_tag="ACL3G6_001540"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HGR0546044.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQAIDRDPLDFLYEVTHKSQHHSDLPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRSVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            3919..4485
                     /locus_tag="ACL3G6_001541"
     CDS             3919..4485
                     /locus_tag="ACL3G6_001541"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HGR0546045.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            4496..5500
                     /gene="trpD"
                     /locus_tag="ACL3G6_001542"
     CDS             4496..5500
                     /gene="trpD"
                     /locus_tag="ACL3G6_001542"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HGR0546046.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            5497..6264
                     /gene="trpC"
                     /locus_tag="ACL3G6_001543"
     CDS             5497..6264
                     /gene="trpC"
                     /locus_tag="ACL3G6_001543"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HGR0546047.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDC
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNTGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            6251..6850
                     /locus_tag="ACL3G6_001544"
     CDS             6251..6850
                     /locus_tag="ACL3G6_001544"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HGR0546048.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVAADLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            6828..8051
                     /gene="trpB"
                     /locus_tag="ACL3G6_001545"
     CDS             6828..8051
                     /gene="trpB"
                     /locus_tag="ACL3G6_001545"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HGR0546049.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            8044..8820
                     /gene="trpA"
                     /locus_tag="ACL3G6_001546"
     CDS             8044..8820
                     /gene="trpA"
                     /locus_tag="ACL3G6_001546"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HGR0546050.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(8792..8893)
                     /locus_tag="ACL3G6_001547"
                     /pseudo
     CDS             complement(8792..8893)
                     /locus_tag="ACL3G6_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            9122..9853
                     /locus_tag="ACL3G6_001548"
                     /pseudo
     CDS             9122..9853
                     /locus_tag="ACL3G6_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9868..11019
                     /locus_tag="ACL3G6_001549"
     CDS             9868..11019
                     /locus_tag="ACL3G6_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0546051.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGNRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(11071..11730)
                     /locus_tag="ACL3G6_001550"
     CDS             complement(11071..11730)
                     /locus_tag="ACL3G6_001550"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HGR0546052.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLL
                     V"
     gene            11800..12246
                     /locus_tag="ACL3G6_001551"
     CDS             11800..12246
                     /locus_tag="ACL3G6_001551"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0546053.1"
                     /translation="MTIRFEEKVSIENAQLVCQWSNSLGKVFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
     gene            12424..12663
                     /locus_tag="ACL3G6_001552"
     CDS             12424..12663
                     /locus_tag="ACL3G6_001552"
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0546054.1"
                     /translation="MNERYQCLKTKEYQALLSSKGRQIFAKRKIDMKSVFGQIKVCLG
                     YKRCHLRGKRQVRIDMGFILMANNLLKYNKRKRQN"
     gene            complement(12773..12976)
                     /locus_tag="ACL3G6_001553"
     CDS             complement(12773..12976)
                     /locus_tag="ACL3G6_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGR0546055.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(13007..13615)
                     /locus_tag="ACL3G6_001554"
     CDS             complement(13007..13615)
                     /locus_tag="ACL3G6_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR0546056.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(13646..13816)
                     /locus_tag="ACL3G6_001555"
     CDS             complement(13646..13816)
                     /locus_tag="ACL3G6_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HGR0546057.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(13828..14394)
                     /gene="amaP"
                     /locus_tag="ACL3G6_001556"
     CDS             complement(13828..14394)
                     /gene="amaP"
                     /locus_tag="ACL3G6_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HGR0546058.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(14478..14642)
                     /locus_tag="ACL3G6_001557"
     CDS             complement(14478..14642)
                     /locus_tag="ACL3G6_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGR0546059.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
BASE COUNT         4666 a         2605 c         3163 g         4324 t
ORIGIN      
        1 gtgaaatggt gtttgccttt catttacctc ctgatgagtt gataacaaat gttatcttta
       61 aagaaaaaat taactctatg ttaaaatgtt acattgacag gctattatat gtttttataa
      121 atcctacaca ttttactgaa aaagttaatc tacaatttta tggtagtttt ttctcatatg
      181 aatttatttg tcgtgaagtt ggaaacattc ttaaaaataa aggtgtgaaa tgcaatttaa
      241 acttttttga aggggaagaa tatttgtaaa attaattttg tgaatttgtg gatcttaaat
      301 aatttactaa attctcttgt taaaaaaaat taaatattgt atagtaatat tagaatgttt
      361 gtaatagagg actgaaatga aaaatataaa tgggaaaaag gtaactattt atgatattgc
      421 acgtttatca ggtttttctc caaaaacagt ttcacgagtt attaatggtg gagtaaatgt
      481 taaagaagaa acttatcaag cgattcaaaa agttatagag gaattgtcgt atattccaaa
      541 tgcgtatgca aaaaatttaa ctaaaaaaga agctataaat atattgattt ctgtaaaaaa
      601 aatcgactct tttcctttaa tttggtttca tacgctgtta gataaagtgt tacggacgtg
      661 taaagaattt ggtgttaatg ctatagttga gtactttgga gaggaggata caattagtaa
      721 ttcaattata tcaagcacag gtagcctagt agatggtgtt attgtttttt atgaaagtgt
      781 agatgatatc agaattcagt atttaaagaa gaaccatatg ccttttcttg ttttcggtga
      841 atctcaaacg tctggagtag tctatgtatc taataataat tttcaagcta cttatgatat
      901 gatgaaagct gtaactgaag aaaaatttaa aaatatgtgg ttgcttatgg gaggagaatc
      961 ccatgttaat aaggatcgtg aaagaggtgt gcgttctttt ctgaatgata aaaattactt
     1021 tatggattta aaagtcattt atggcttatc tacaattgat tcagtttatt cttatgcaat
     1081 gcagcacttg actacccaaa attatccgga cattattttt gtttcaggag atgaaaaggt
     1141 tcagggcttg attcgtgcgt gctatgagaa aggaattctt attccagatg atatttctat
     1201 cattggattt gataatattc ctatttctca gtattatact ccagctttgt ctacaattgc
     1261 tcccaattat gttaaattgg ctaaagaaat gatagaaggt gttttagcaa ttattaaagg
     1321 ggaaagtgtc acatctgttg aagtttctcc taaatttgtt aggagacaga gtttctagta
     1381 ttgtttaatt cttgaaaatc ctagtggaaa agatggagtg ttctaaaata agttctgttt
     1441 agcctccatt cagtttctat tgagttggat ccaatttcta acaagtggga catgttcatg
     1501 ttcgatctaa ggaagatatg gtcacattcg aatgatatca aaaaaatcgt aaaaaagtct
     1561 tgacaaagaa aaaacaaagt attaaaataa gttcaacaaa tcagaaaagt aactattttt
     1621 gatcttcagg gagcctgtgg tgattgtgaa taggtggttg gaagtagtga aagtgggctg
     1681 attttgaaaa tgaatttgaa acaatgaaaa ttcggtgcgc acaccttaca gtgcagcttg
     1741 ttgttaaaca aggcagagat gtaaagggat agtcccttta taattgaggt ggcaccgcgt
     1801 taccaacgcc ctcacacgga agtatattct gtgtgtgggc ttttttctat ccgtcgtttg
     1861 gtttatcttt tattagggcc ttaagtcgct ttgatgaact tgagttctat ctacagctcc
     1921 ttgcctccta ctaaaagtaa acaaaaaggc tggactaata cgaaaaaagc tagtaatact
     1981 caatgaaaat caaagagcaa actaggaaac tagccgcagg ttgctcaaaa cactgttttg
     2041 aggttgtgga tagaactgac gaagtcagct caaaacactg ttttgaggtt gcagatagaa
     2101 ctgacgaagt cagtaaccat acctacggca aggcgacgtt gacgcggttt gaagagattt
     2161 tcgaagagta taaaggtgta ccgagatgaa catctcttca tcaatgtctc tggtcgtgga
     2221 ggcaaggacc tagctgcgat tgcagattac tagaagctaa aaaataatag atggaaaaat
     2281 tacagtcttt tctctcacag agagcttgtg gttgctgaaa acaagcagag aaagctgtaa
     2341 agttgggttc atctgaaacg agagaagaaa acatcattct caagggagtg ccctttatcg
     2401 cacagcctgt tacaggagat atctgagaca ggaatgagag ataggagaaa tcctataatt
     2461 gaggtggcac cgcgaatttc gtcctcacgc aagttatttt gcgtggggat ttttcataca
     2521 gtcgccacga actagaatta gaactgaaag ggaaatgaca atggaacgaa tcattcatgg
     2581 agatgtctta tcaccaatct tggcttatat gcgcttaaag gggcaacata aggttatttt
     2641 agagagtatt ccgagagaca aggaaacagc tcgtttttct atcctagcct ataatccagt
     2701 ttttgagatt aagtttgaaa atggagttct ctatcaaaat ggtcaagcga ttgatcggga
     2761 tcccttggat ttcctttatg aagtgactca taagagccag caccattcag acctcccttt
     2821 tggtggggga gccattggtt ttgttggtta cgatatgatt tcgctttatg aagaaattgg
     2881 tcaaatccct gaggatacaa ttgggacgcc agacatgcat ttctttgtct atgagagcta
     2941 tatggtcttt gaccacaaga aggagaagat acatgtcata gaggatgcac tttatagtga
     3001 gcgcagtcaa gaggccttgg aaaaatcctt gaaccaagtg cttgaggaat tacgcattcc
     3061 tgctccaaat gaatttgaag acttggattt atcaccactt gacttcaaac cgcatatcgc
     3121 tccacataag tttgagggaa tggtagaaac agctcgtgac ttgattcgta acggagatat
     3181 gttccaatgt gtactcagcc agcgtttctc agcagaagtt actggaaatc catttgactt
     3241 ctacagaaat ctccgcgtga ctaatccatc taattacctt tatttctatg attttgggga
     3301 ttatcaaatc atcggagcta gtccagaaag tttggtttct gtcaaaaatg gcatcgtgac
     3361 aactaatccg attgcaggga cgcgaccaag aggggctacg gatgaagaag acaaggcctt
     3421 ggcgactgac ctcctctctg atgagaagga aacagcagaa catcgaatgt tggtagactt
     3481 ggggcgtaac gatattggcc gcatctctga aacggccagt gtccaagtta ctaagtatat
     3541 ggaggtggag ctcttccgct acgtcatgca tttgaccagt gtggtcaagg gacgtttgct
     3601 tgcagaactc actgccatgg atgccttgaa agcaacgctt cctgctggaa ccgtttctgg
     3661 agcaccaaaa attcgagcta tgagacgcat ctatgaactg gaaacggaaa aacggagcgt
     3721 atatgcagga gcaatcggct acttgtctgc gacgggtgat atggatttgg ccattgccat
     3781 ccgaaccatg attctcaaaa atcaaagagc ctatgtgcag gctggggcag ggattgtcta
     3841 cgactctatc gcccaaaacg aataccaaga aaccattaac aaagcaaaat ctatgactag
     3901 aattggagaa ctaagaccat gattttattg attgacaact atgattcttt tacctataac
     3961 ttggcccaat acattgggaa ttttgcagaa gttcaggttt tgagaaatga tgattccaag
     4021 ctgtatgaag aagctgaaaa agcagatggt ctggtctttt ctcctggtcc tggttggcca
     4081 gttgatgctg gaaagatgga agacatgatt tgtgattttg caggcaagaa gccgattcta
     4141 gggatttgtt tgggtcacca agccattgca gaagtctttg gtggtaagct aggtttggct
     4201 ccaaaagtca tgcatgggaa acagagcaat atcaactttg aagcgccatc tgttttgtat
     4261 caaggtattg aggatggacg tgcggtcatg cgttatcaca gtattttgat tgaggaaatg
     4321 ccagaagact ttgaagtgac agctcgttcg actgatgacc aagccatcat ggggattcaa
     4381 cataaaaacc taccgattta tggcttccag taccatccag agagcattgg aacgccagac
     4441 ggcttgtctt ctattcggaa ttttatcgag aaggttgtaa agtgaggaaa ctaggatgaa
     4501 agagattatt gaaaaactag caaaatttga aaatttatca ggtgtggaaa tgacggatgt
     4561 cattgagcgt atcgtaactg ggcgtgtaac tgaagcgcag attgcttctc tcctcttagc
     4621 tcttaagatg aagggggaaa cacctgaaga acgtacagcc attgcccaag tcatgagagg
     4681 acatgcccag catattccaa ctgagattca tgatgctatg gacaactgtg gtacaggtgg
     4741 ggacaagtct ttcagtttta atatttccac aactgcagcc tttgtcttgg ctggtggcgg
     4801 tattcacatg gccaagcatg gtaaccgctc gatttcttct aaatctggtt ccgcagatgt
     4861 cctcgaagcc ttgggaatca atcttgacct caaaccagct gaactaggta aggtctttga
     4921 taaaactgga atcgtctttc tcttcgctaa aaatatgcac ccagctatga aatacatcat
     4981 gccagctcgt ttggaattgg gaattccaac gattatgaac ttgactggtc cactgattca
     5041 tccaatggct ttagaaacac agcttcttgg aattagtcgt ccagaactcc tagaaagtac
     5101 agctcaggtt ttgaaaaata tgggtcgcaa acgtgccatc gtggttgctg gaccagaagg
     5161 gttggatgaa gctggcttga acggaacaac caagattgca cttcttgaaa atggcgaaat
     5221 cagcttgtca agctttactc cagaggattt gggaatggaa gactatgcta tggaagatat
     5281 tcgtggtggg aatgctcagg aaaatgcaga aattttgctt agcgttctga aaaacgaagc
     5341 aagtccattc ttggaaacga cagtcttgaa tgctggtctt ggtttctatg ctaatggtaa
     5401 gattgatagc atcaaggaag gagttgcctt ggcccgtcaa gtgattgcta gaggcaaggc
     5461 ccttgaaaaa ctcagactgt tacaggagta ccaaaaatga gtcaggaatt tttagcacga
     5521 atcttagagc agaaggcgcg tgaggtggag cagatgaagc tggagcaaat ccagcctctg
     5581 cgccagacct atcgcttggc agaatttttg aagaatcatc aggactgctt gcaggtaatc
     5641 gctgaggtca agaaagctag ccctagtttg ggagatatca atctcgatgt ggatattgtg
     5701 caacaggccc agacttatga agaaaacgga gcagtgatga tttcggtgtt gacagatgag
     5761 gttttcttta aagggcattt ggattatcta cgggaaattt ccagtcaggt agagattccg
     5821 acgctcaaca aagactttat catagatgaa aagcaaatca tccgcgctcg caatacaggt
     5881 gcgacagtta tcttgcttat tgtggcagcc ttgtccgaag aacgcctcaa ggaactgtat
     5941 gactacgcga cagagcttgg tctggaagtc ttagtggaga ctcacaatct agctgaacta
     6001 gaggtagccc acagacttgg tgctgagatt atcggggtca acaaccgcaa cttgactacc
     6061 tttgaggtcg acttgcagac cagtgtagat ttagcccctt actttgagga aggtcgctat
     6121 tacatttctg aatctgccat tttcacaggg caggatgcgg aacgactagc cccatacttt
     6181 aacggaattt tggtagggac agctcttatg caggcagaaa atgtggccca gagaatcaag
     6241 gagttgcaga ttgacaaagg ttaaaatttg tggactatcg accaaagaag cggtggaaac
     6301 agccgtttca gcaggagccg actatatcgg ttttgtcttt gcacctagta aaagacaggt
     6361 gactttagaa gaggcagctg agttggcaaa gcttattcct gcagatgtga aaaaggttgg
     6421 agtatttgtt tcaccaagtc gggtagaact gctggaagcg attgacaaag ttggcttgga
     6481 cttggttcaa gttcacggtc aggtggcagc tgatttattt gagaatttgc cttgtgccag
     6541 tattcaggct gtgcaggtag atggaaatgg gcatgtcccc aattctcagg cagattatct
     6601 actctttgat gcccctgtgg caggaagtgg tcagtccttt gattggggtc aactggatac
     6661 gactggacta gcacagccct tctttatcgc aggtggcctt aatgaagata atgtagtaaa
     6721 agcaattcaa cattttactc cctatgcagt agatgtatcg agcggagtgg agacagatgg
     6781 acaaaaagat catgaaaaga ttagaagatt tatagagagg gtaaagcatg gcatatcagg
     6841 aaccaaataa agatggattt tacggaaaat tcggcggacg ttttgtccca gaaacattga
     6901 tgacagcagt tttggagttg gagaaggcct accgtgaaag tcaggcagac ccaagtttcc
     6961 aagaggaatt aaaccagctt ttgcgccagt acgtaggacg tgaaactcct ctttattacg
     7021 caaaaaactt gacccagcat atcggcggag ccaagattta tctcaaacgg gaagacctta
     7081 accatacagg agcccacaag attaacaatg ccttgggaca agtttggctt gccaaacgca
     7141 tgggtaaaaa gaaaattatc gcagaaactg gtgctggtca gcacggtgtg gcaactgcaa
     7201 ctgctgcggc cctctttaac atggaatgta ccatctacat gggtgaggaa gatgtcaaac
     7261 gccaagccct caatgtcttc cgtatggagc ttttgggagc taaggtcgag gccgtgacag
     7321 atggttcgcg cgtgctcaag gatgcggtca atgcagctct tcgttcatgg gtggctaata
     7381 tagatgatac ccactatatc cttggttctg ccttggggcc tcatccattt ccagaaattg
     7441 ttcgtgactt ccaaagtgtc attggtcgag aggctaaaca acagtaccgt gacttgacag
     7501 gacaaaatct gccagatgcc ctagtagcct gtgttggtgg tgggtcgaat gccattggtc
     7561 tcttccatcc ctttgtagaa gatgagtcag tagccatgta tggagctgaa gcggctggac
     7621 ttggtgtgga tacggagcac cacgcagcta ccttgaccaa gggtcgtcca ggtgtccttc
     7681 acggttccct catggatgtg ctccaagatg cccatggtca aattcttgaa gccttctcta
     7741 tctcagcagg tttggactat cctggtatcg gtccagagca ttctcactac cacgatatta
     7801 aacgtgccag ctatgtccct gtgacagacg aagaagcctt ggaaggattc caactcttgt
     7861 ctcgtgtgga agggattatc ccagccttgg aatctagcca tgctatcgcc tttgcggtga
     7921 aattggccaa agaacttgga ccagaaaagt ctatgattgt ctgcctatca ggtcgtgggg
     7981 acaaggatgt ggttcaagtc aaagaccgct tggaagcaga tgcagcaaag aagggagaag
     8041 ctcatgccta agacactaac aaaaaaatta aatgctatta aagcagctgg aaaaggaatt
     8101 tttgttccct atatcatggc tggtgaccac gaaaaaggtt tggatggtct tgctgaaaca
     8161 attcactttt tagaagattt gggtgtctct gcaattgaag tgggtattcc cttttcagac
     8221 cctgttgcag atggacctgt tatcgaagaa gctggcttgc gcagtttagc ccacgggacc
     8281 tctacccagg ctttagttga aaccttgaaa accattgaaa cagagattcc actggtcatc
     8341 atgacctact tcaaccccct ctttcagtac ggtgtggaga actttgtcaa agatctggct
     8401 gatacagctg tgaagggctt gattatccca gacctgcctc atgaacatgc caactttgta
     8461 gaaccatttt tggcagatac agatatcgcc ttgattcctt tagtaagctt gaccacagga
     8521 attgagcgcc agaaagagtt gattgaaggg gcggagggat tcgtctatgc cgttgccatc
     8581 aatggggtaa cagggaaatc aggcaattac cgtgcagatt tggacaagca cttggcgcaa
     8641 cttcatcaag tggccgacat cccagtcttg acaggttttg gtgtatctag tcaagccgat
     8701 ctggaacgct tcaatgcggt gtcagatggt gttatcgtcg gttcgaaaat agtaaaagct
     8761 ctccaccaag gagagccgat tcaggacttt atcaaacaag cagtagctta ccaaaaataa
     8821 ttaaacaagt agcaagtaag aggaaaggca cgaaaggaag tctttccttt ttcttttgca
     8881 ggcgaaaggc tagttttata gtgaattgaa tctggaatat tacactacgg ttcctaaaat
     8941 attttaagaa agtgatttga atttcccaat aaatttgttc agtttttaat tgattttact
     9001 atagaagata taattttcta aattactctg acacagaact ttaagaaaaa gctaattatt
     9061 gtagtaattt ctttaagaaa atgatataat tcattaaaaa gtatttggag gaggaagaat
     9121 tatgttgaat caggatctct ttgattcgct tgaggcacaa aaaattgtag atactttgat
     9181 gaaagggcaa aaagattatg tagatgaacg tctagaaaaa agagagacaa tgatagtgtc
     9241 gaatggttat gcatggacgt gacctaatca tattgatact gcatttgcat cagcagattt
     9301 gtttgagtat aaattacaat tagcaggaca gacttgggga tatttagaat ttgaaacaaa
     9361 tacagaaaaa tatgggaaag tattgttaat tataaagggt aagaagcgac ttacgaacca
     9421 atttcctttg gtacaaaaaa ataagagtgg ctacttattt gaatatgctc agatgaatac
     9481 actttatctt aatcaacatt cttcctacaa aaatgatgaa gatagtcatt cctttccaat
     9541 tcagatggag ttagtttctg atgaaatgat tcaagaaatt gaacaagcta ctaaaaattc
     9601 gaatatcgaa aaatttatga ttttaactta tgaggcggac tcagaaaaca atattatatc
     9661 tgtagatgtt gttatgcctg atgcacgaac tggtcagtta cacttgattc aagatttgtc
     9721 tgagtatatt caatcaagtt cgtaccattt cgaagaagct aaatatcaag atattcctaa
     9781 tttttcagaa ttatcggaaa cagaagattt tgaaattatt ccaagaatag aaaaacaaga
     9841 aggtcaaaag tagtaaggaa tatgtaaatg tttaatggtc gggtattgaa agaattacgg
     9901 ctgttaaatg gtttaagtag agcagaatta gctcagagaa ttaatttaac ggaacaagcc
     9961 atttggcagt ttgagtccaa cgaaacgaaa cctaaattat caaccaaaat gcatttggcc
    10021 aaccaatttc atgttgattt aacttatttt gaacaggaag aagagagcat tcgatttgat
    10081 tcttctgtaa ttgcctttag aaatgcagac ctagcaacac ggaaaacaat agatattcaa
    10141 actatgtatt tacataaggt agatagtttg attgattatt ttgaaagttt tgtaattata
    10201 cctaatatta caattcatga cctaagtaat gtagtgagtg aatcttatca taagggagaa
    10261 tccattgagg aattggctct ttatgccagg gaaaaattag gtatttcaaa agataatcat
    10321 gatttgcttt ataaattaga acgttcaggc atctatatcg tggaacgatt aattaatggc
    10381 caagctgatg cttatagcgc atggtcaaaa ttgggaagac cttatattgt gttgggaacg
    10441 aataaatcat ctgtacgtcg aaattttgac ttagctcatg agctaggaca tattctttta
    10501 cacaaatata aagatatgaa tgaagatggc aatcgtttgg agcaagaagc aaattatttt
    10561 gcatcatgtt ttttattgcc aaaagaagag tttttagtca aatttgaaga gagggttggc
    10621 aagcgtgtca gcaatcctga tagttatatt ttattgaagt cggatttgaa tgtttcgata
    10681 caggctttag agtatcgagc ttttaagtta ggattattga ctccaaagca acattcttac
    10741 ttttatcgtc aaattgcgca aaaaggttac aaaatgattg aacctttgga tgatcaaatt
    10801 tttgttaaaa aaccaagcaa agtaaagagt attctggacg tcgttttgag taatcatcta
    10861 gtcagtctag cgactataat gtctaaacaa agtattcgtt tacagtttat aagcgaaata
    10921 ttttcagtcg aaatgaaatt ttttgatcag tatcaagaag atagaagaac agatcgattt
    10981 gataacatca tccctttgta caaaagaaat aatttataat ttaactgtga aataatttca
    11041 tgaaggacat atggcagaaa ttggatttta tcagacaagc agtagcttac caaaaataat
    11101 cacacaagca gcaagtaaga ggaaaggcac gaaaggaagt ctttcctttt tcttttgcag
    11161 gagaaaggcc agaatacccg tcgcagaagc gaactgaatc aagatcagta actccgttac
    11221 gctaaagacg agagcacaag aagctaaaaa gaggaaatct cctgcgccca tgcggatatc
    11281 gataaaatga gccaaaattc caagagcaag gaaggagacc atgaccagat tccagccaga
    11341 ggaagctatt aggattaggt ggaaagtcat ccagaccagt aagggatatt cctgatggcg
    11401 aaagtcgtag atgcctaagg tcaaaccagc ggtgattagg acgacttgcc ccaaggaaag
    11461 caattcccaa gagtaaagca gaaagaggag tcctaagact aattcaaaga gggcatacca
    11521 gacaggatag cgaactttgc agtagcgaca gcgaaagcga ttgaagacct gtgagagaat
    11581 cggaatcaaa tctaagggac gcaagcgagt ctgacaggaa tcgcagtgac tggctgaact
    11641 gataatggat tgctctggaa aacggtcaat gaccaaacca agaaaggaag cgagaatgct
    11701 cccgacgaga aaaaaataaa aatcaatcat acttatctat tcgtaaaaaa tgggagaaat
    11761 agtataatgg agaaacatag ataagatggt gaggaaaaga tgacaattcg ttttgaagaa
    11821 aaggtgagta tagaaaacgc tcagctcgta tgccaatggt ccaactcctt aggcaaagtc
    11881 tttcaagaac aatggatggg accaaggatt ccttttctac tgacccttca agccttggaa
    11941 ggagtctttt caatctttga tgaacaagag tttgtgggac ttatccagaa aatcaggcta
    12001 gaagacagca atcttcatat cgggagattt tttatcaacc cccagaaaca ggagcaaggc
    12061 ttaggtagcc aggctttaag gaaatttgtt agtttggcct ttgaaaatga agatatagat
    12121 agtatttctc taaatgtctt cgaggcaaat caaagagctc agaatcttta ccaaaaagaa
    12181 ggatttgaaa tcgttcaaat ggttgaagca cctgtacgaa aatatagtag attgaaacta
    12241 gaatagtaca cctctacttc taaaacattg ttagaaatcg atttgactgt cccgatcgat
    12301 tcgtcctgtt attatttcat tttactatac attatgaaaa aggggagata gaaagcaaac
    12361 agccttgaaa tcaatgttga ctgcgattat gaacctgaat cagcccctca aaagggactg
    12421 tatatgaatg aacgttacca gtgtttaaaa actaaagaat atcaggcact tttatcttcc
    12481 aagggtagac aaattttcgc taaacgtaag attgatatga aatctgtctt tgggcagata
    12541 aaggtttgtt tgggttataa gagatgtcat ctgagaggta agcgtcaagt gagaattgac
    12601 atgggattca tactcatggc caacaacctg ctgaaatata ataagagaaa gaggcaaaat
    12661 taaaaagcta gagttccgca attgggaatc tctagctttt tgttttctga gaatcatctt
    12721 gactcagact cttttgacta atgttaccaa aaagataaag taacttttaa ccttatttat
    12781 cgtcgccact caacatgttt ttaacacctt ctacagcacc ttctacagcg tctttagcgt
    12841 cttcggcaac ttcttttact ttagaaacaa ctttttcagc tgctccttct ttttccattt
    12901 tttcatcacc gatggctttc ccaacacctt ctttaataga acctttagct tgatttaatt
    12961 tttcttctac tgacatgata atttctcctg ttatatttat tttatcttag tttacacgag
    13021 tgttttcgtg agatactaca ccatttgctg cacctttaac agcttctaca ccttcgctaa
    13081 ctttttcttg aacagttgag aaaccagatc caagaccaga tttagctttt tcgaattgtt
    13141 ctgaagtgaa ttctcctgtt gattcagcaa cgtcagatac gcgatcttga aggcttactg
    13201 agtctgcttc atgctgttct ttagttttga tgtcgacaac gtttacgttg atttcaacaa
    13261 tttccaagtc agtcatttta gcaacttctg aagatacgat ttctctgatt tctgaatata
    13321 aagctggaac atttttttgg tactcaacaa taacgtttaa gtcaactgca acttgtgttt
    13381 taccaacttc tacgttaaca ccacttgtta cgtcatcgct gttaacgatt ttttctttaa
    13441 gatttgagaa gaaaccacca tcgattccca aaagacctga aacgttttct agtgaaagac
    13501 caatgatttt ttggataact ttatcttcgt aagtaagttc ccctttgatt tcgtgagcta
    13561 caacagtagc atctttcttt tctacgttag tatttgtgtt tttttcgttt gacatatgaa
    13621 actcctttaa ttaaattagt aatttttatt tatctatata gtttttttcg atatataatc
    13681 cagctgcaac tcccagtgct cctaaaatca atacaaatat tgttttgaag aagccaaagg
    13741 agacaatcaa acaagccaga aatacgccta tgagaccagc gataattgga tatcgatatt
    13801 gtttaagcca ttccattttt tacttcctta cttcacacga ctaacagtct ttttgttttg
    13861 aggttttggt tggtaatttt ttactgcaac ttcaagtttt acttgacgct caataccaaa
    13921 aaactgcttc aatccattag ttatttcatt ttgaattatt tggcatctgt cagcgatgtt
    13981 gtctgaagga agaattttac cttctacatg aacgaaacat ttattttttc gtaaatttac
    14041 atgaacagtt gggttcttga tcaatctatg atcactcacc aaacttctaa caaaaccttc
    14101 gattgccgaa ttctttaatt ttaatgtatc gtttttagtt tcaagttgga tttccaagta
    14161 acgtttagga taaaacatca caactaaaat ggataataaa actaaagttg atagaaccac
    14221 tgtcccccaa aagacatatc tagcaagata gaattcaact acggagttct gtctccagct
    14281 aagtagatga atacctagat cactaacttg atgataatct atcaaaacag gaaggaaaat
    14341 tgtcaagatt aaaatacaga aaataatgaa acatattttc tttgcttttg acatatacaa
    14401 tcctttcgat ttaacattta aactattttt cccgtcattg atttaaaaat agtttgctaa
    14461 ctttactggc gaaaagttta ctttctacct gtaaagaatg acactacagt aatcacaatc
    14521 gctgcaccta caatagatgg gagcaaagcc attccagcga ttgatggacc ccaactacct
    14581 aaaagagatt gtcctgcata tgccccgact aaaccagcga atacatttgc gatgattccc
    14641 atagaactac ttttttagtg attttacctg ccaagagacc aataagacct ccagcaataa
    14701 ttgatcacaa cactgcctac cctccttttt tattttaata tcaaaaaatc aatttctt
//
LOCUS       DBEJKC010000047        14510 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.047, whole genome shotgun sequence.
ACCESSION   DBEJKC010000047 DBEJKC010000000
VERSION     DBEJKC010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14510
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.047"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            250..1695
                     /gene="cps4A"
                     /locus_tag="ACL3G6_001558"
     CDS             250..1695
                     /gene="cps4A"
                     /locus_tag="ACL3G6_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HGR0546060.1"
                     /translation="MSRRFKKSSSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     IDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVLEIDDSSLAVVKAAIQDVMEGR"
     gene            1697..2428
                     /gene="cps4B"
                     /locus_tag="ACL3G6_001559"
     CDS             1697..2428
                     /gene="cps4B"
                     /locus_tag="ACL3G6_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HGR0546061.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRIIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     gene            2437..3129
                     /gene="cpsC"
                     /locus_tag="ACL3G6_001560"
     CDS             2437..3129
                     /gene="cpsC"
                     /locus_tag="ACL3G6_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HGR0546062.1"
                     /translation="MKEQNTIEIDVFQLFKTLWKRKLMILIVALVTGAGAFAYSTFIV
                     KPEYTSTTRIYVVNRDQGDKPGLTNQDLQAGSYLVKDYREIILSQNVLEKVATNLKLD
                     MPTKTLASKVKVTVPTDTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLQIP
                     LLGVVPDLNKMK"
     gene            3139..3828
                     /locus_tag="ACL3G6_001561"
     CDS             3139..3828
                     /locus_tag="ACL3G6_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HGR0546063.1"
                     /translation="MPTLEISQAKLDFVKKAEEYYNALCTNLQLSGDDLKVFSITSVK
                     LGEGKSTTSTNIAWAFAHAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNVENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEVGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSY
                     GNYGDYGKNKK"
     gene            3844..5211
                     /locus_tag="ACL3G6_001562"
     CDS             3844..5211
                     /locus_tag="ACL3G6_001562"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGR0546064.1"
                     /translation="MNGKIVKSSLAIIQSFLVILLTYLLSAVREAEIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGEL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIMGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGCFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     gene            5242..6414
                     /gene="cps2T"
                     /locus_tag="ACL3G6_001563"
                     /gene_synonym="wchF"
     CDS             5242..6414
                     /gene="cps2T"
                     /locus_tag="ACL3G6_001563"
                     /gene_synonym="wchF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta 1-4 rhamnosyltransferase Cps2T"
                     /protein_id="HGR0546065.1"
                     /translation="MKQSVYIIGSKGIPAKYGGFETFVEKLTEYQKDGNIQYYVACMR
                     ENSAKSGFTADTFEYNGAICYNIDVPNIGPARAIAYDIAAVNKAIELSKGNKDEAPIF
                     YILACRIGPFISGLKKKIRSIGGRLLVNPDGHEWLRAKWSLPVRKYWKFSEQLMVKHA
                     DLLVCDSKNIEKYIREDYKQYQPKTTYIAYGTDTTPSSLKSEDAKVRNWYREKGVSEN
                     GYYLVVGRFVPENNYETMIREFIKSKSNKDFVLITNVEQNKFYDQLLKETGFDKDLRV
                     KFVGTVYDQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     DGAIYWKKDELAHVIEEVERFDEGDITELDEKSSQRIADAFTWEKIVSDYEEVFTV"
     gene            6411..7694
                     /locus_tag="ACL3G6_001564"
     CDS             6411..7694
                     /locus_tag="ACL3G6_001564"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR0546066.1"
                     /translation="MKILHYTLGFQPSRTGGLVKYAEDLMTQQATDGHEVIALYPGEI
                     SIIFRQVRIKKAENRKFQCYKIINSLPLALFGGISEPDEFMKSCDKASYRKFLKNIKV
                     DVIHIHSLIGLHKEFIEVAKELGIKTVFTSHDYYGLAPVPHFYFNGVDYSSNNTNLAW
                     NIMSSNALSVKKLRFFQVSFYPTIRKLMKMLGKNPKSKKNLVIRDITEAIDYSALRSY
                     YKAMFGLIDAYLFNSQLAKEVYEANHIIPKNNIIVSISNSSISNHNIRVSSGEKTVVA
                     YIGPDEEYKGYFDFLDIVNDLDQEKYDIKTYGHFPNEDCPPYIQQNGYFTKDTVGSVY
                     SNIDILIVPSRWKETFGLISIEALSYDVNVFVSKNVGSKDLVSEEHIFHNKDDLLKKI
                     QYVKFENVKFKTMKEHMVEIINYYERITNDNQKIN"
     gene            7657..8361
                     /locus_tag="ACL3G6_001565"
     CDS             7657..8361
                     /locus_tag="ACL3G6_001565"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HGR0546067.1"
                     /translation="MKGLQMIIKRLIKTITGKEIDLHPDIPITYILQRGFQYGLGLSR
                     GLLRGIGLGKKGKRLFIGRGVTLLAKRKLYVGNNIRIGKYVSIDCLSKDGIQIADNVK
                     IGDYSQIIGTGSVKNMGIGLKIGKNSSFSEYSLFGSAGGITIGGDVIAGQNVRFHAEN
                     HSYEVLHIPIREQGVNRKGISVGDNCWIGAGAVFLDGSSIGSGCIVATNAVVTKKFPD
                     NVIIGGVPAKILMERK"
     gene            8405..9640
                     /locus_tag="ACL3G6_001566"
     CDS             8405..9640
                     /locus_tag="ACL3G6_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HGR0546068.1"
                     /translation="MKIAVVGTGYVGLSISVLLAQHHHVVAVDIVKEKVELINKRISP
                     IQDDFIERYLSESNLDLVATIDAETAYKDASFIVVATPTNYDLERNFFDTSTVESVIQ
                     QVQNMNSTATIVIKSTVPVGFTDSIRKKLGISNLLFSPEFLRESRALYDNLYPSRIIV
                     GTDLSNQKLVEKAQVFSNLLVQGAIKKDIPILTMGFTEAEAVKLFANTYLALRVSYFN
                     ELDTYAEIKGLDTQKIIEGVSLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYKNVPE
                     ELIGAIVRSNTTRKDFIANQVLKVVNYNIPEDDIPTKQMEKEVVIGIYRLTMKSNSDN
                     FRQSSIQGVMKRIKDRGVKVIIFEPTLKDSDTFFGNAVINDLEEFKVKCDVIIANRYD
                     ETLNDVKDKVYTRDIFRRD"
     gene            9648..10772
                     /locus_tag="ACL3G6_001567"
     CDS             9648..10772
                     /locus_tag="ACL3G6_001567"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR0546069.1"
                     /translation="MKKVLIVRSGPYQVNPEGYNLQELGLASAISQQGYQCDVMYYHK
                     TKNYDQLYEKNGEQIKIFWRRGIRLFRSGIYPQILREKFLNQYDKIIISEYSQIMAVL
                     LSRIHSNVYIYNGPYYNLFKIPIIEPIYDFLFVEMLNKRTKTVFCKTEKAECYLKNKG
                     FNDCKVVGVGLDIEKFEQEEEPTEDTIELLRRMENKQNILYVGSLSKRKNTAQLIRIF
                     NILKSKSGKKNELQLVLIGKDEDNIVEKINYSRFKDDIIYQPYLKNSQLQFIYPSSQL
                     LVLPSVQEIFGMVLLEAMYFKLPVVSSASAGGETLIQDGINGKIVNDFNDEHWVDCIE
                     NLLNNPLELKRLGECAHKRITEQFMWSSIARKIIETFDER"
     gene            10781..11623
                     /locus_tag="ACL3G6_001568"
     CDS             10781..11623
                     /locus_tag="ACL3G6_001568"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR0546070.1"
                     /translation="MNFCFVILHYRTSNDTIECIKSIQKLEGDYKIVIVDNASQNGSI
                     ERVEALFANNDEIVIIKNTKNLGFAAGNNIGYAYARTQIKADMIAVLNNDIVIKQKDF
                     INRIFELYRNSQFHIAGPDIVSLVDGHHQSPVVEKINSISKANKELFKYRILRIINKI
                     GLYELMTRQPKKELNRISVADPMRYQENVILHGSFVIFSPLYVSEEECAFRPDTFMYM
                     EEPILYEYCMLKNYKTVFDPSIVIYHKEDSSTNSLYNAAYAKREFVFKNMIRSLKIYR
                     SLLK"
     gene            11665..12933
                     /locus_tag="ACL3G6_001569"
     CDS             11665..12933
                     /locus_tag="ACL3G6_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008755 - O antigen polymerase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polymerase"
                     /protein_id="HGR0546071.1"
                     /translation="MLALTIGTVVFVKKTYRTFLNPIILFVILWFIITTLSSLKLFQL
                     FEISTHTQQIILLGTSLFVIGGGIAIWFRDKFYFKVGGNSYFTTDFEINYNLFFLLGI
                     ICLFYYLPDFFSSLVSLIRGGNLNLVRQSAQDAVDTSGLKNFIGTFIVSPSAMVLEIL
                     GVLDFWSNKKGRKLFYLSLAVIFVRVIADAGRTPLFNVVIYLLLTVLANRFSEKTEKK
                     RKVSKIKIVNYGMLGSIILWLSTLSRTTTSVYRILYFYFAMSPILLEKWSSVLDSEKL
                     VTKGLVSLNGFFFSISYVLKNLFRIDYSQRVLEAYTMIANTDAIWYNIAPGLTKANAY
                     VSLFWFFYADGRLLGVLIGSLLYGTFCGYIFCRYIQQQNKKNLAMLLFIYQGVFFSFI
                     RFPFSKSNYAIAFVLLLFFAFKKKGIEKSV"
     gene            12926..13933
                     /locus_tag="ACL3G6_001570"
     CDS             12926..13933
                     /locus_tag="ACL3G6_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546072.1"
                     /translation="MFNINDQSIIYVACPYFNKTGGTELVHQLVYSINHFGGKAIVAY
                     YGSESAPNKVNPAFREYVSTFVDIKDVIDSLDNIIILPEINPDLAANLESIQKAVWWM
                     SVDNYLKRNGILGSLEHFGLLRTIKLFVKGNIKIGGYRIDKEIPHLYQSEYAKQFLLA
                     KGVKKYYRLSDYLNESYIQRSISTDTKKDVILYNPKKGIEFTRELIKQAPELTFSPIE
                     NMSTEQVKKLLSKSKVYIDFGNHPGKDRFPREAAISGCCVITGKRGSAKYYKDIPIPD
                     SYKFEDTVENIPNIIETLKSCLKNYDKHTVDFEKYQQYIKSEHDLFERDVKELFTRNR
                     G"
     gene            13938..>14510
                     /locus_tag="ACL3G6_001571"
     CDS             13938..>14510
                     /locus_tag="ACL3G6_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000107550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGR0546073.1"
                     /translation="MSTRNSLIKNSLYNVAYRMLNIIFPLVSATYTARIILASGVGEV
                     SFAQNVVSYFTTIAAMGIPNYGIREIAKTRNKAEATNKVFSELFLINGLSTLLCSIVY
                     LILILTFNSIFDNTSMYLAVGLTLVFNFLNIDWFYQGKEDYAYITKRSFSIKLISLFS
                     LFIFVRDTDDAVNYALISSLAIGGNNIFNLV"
BASE COUNT         4800 a         2134 c         2947 g         4629 t
ORIGIN      
        1 aagattatac cacattgtgt actatattat attgaaacta gaatagtaca catctgcttc
       61 taaaatattg ttagaaaacg atttgactgt cctgatcaat ttgtcatgtt cttatttcat
      121 tttactatat ttttggttcg cgggaagtct actaagatac ttaaagatgc agatagtgaa
      181 aataaaggtg tagacattac cgtaaaaaag tgatataatc gtatgatgtt caatgtatag
      241 gtgttaatca tgagtagacg ttttaaaaaa tcaagttcac agaaagtgaa gcgaagtgtt
      301 aatatagttt tgctgactat ttatttattg ttagtttgtt ttttattatt cttaatcttt
      361 aagtacaata tccttgcttt tagatatctt aatctagtgg taactgcgtt agtcctacta
      421 gttgccttgg tagggctact cttgattatc tataaaaaag ctgaaaaatt tactattttt
      481 ctgttggtgt tctctatcct tgtcagctct gtgtcgctct ttgcagtaca gcagtttgtt
      541 ggactgacca atcgtttaaa tgcgacttct aattactcag aatattcaat cagtgtcgct
      601 gttttagcag atagtgagat cgaaaatgtt acgcaactga cgagtgtgac agcaccgact
      661 gggactgata atgaaaatat tcaaaaacta ctagctgata tcaagtcaag tcagaatacc
      721 gatttgacga tcgaccagag ttcgtcttac ttggcagctt ataagagttt gattgcaggg
      781 gagactaagg ccattgtctt aaatagtgtc tttgaaaata tcatcgagtc agagtatcca
      841 gactatgcat cgaagataaa aaagatttat accaagggat tcactaaaaa agtagaagct
      901 cctaagacgt ctaagaatca gtctttcaat atctatgtta gtggaattga cacctatggc
      961 cctattagtt cggtgtcgcg atcagatgtc aatatcctga tgactgtcaa tcgagatacc
     1021 aagaaaatcc tcttgaccac aacgccacgt gatgcctatg taccaatcgc agatggtgga
     1081 aataatcaaa aagataaatt aacccatgcg ggcatttatg gagttgattc gtccattcac
     1141 accttagaaa atctctatgg agtggatatc aattactatg tgcgattgaa cttcacttct
     1201 ttcttgaaaa tgattgactt attgggaggg gtagatgttc ataatgatca agagttttca
     1261 gctctacatg ggaagttcca tttcccagta gggaatgtcc atctagactc tgagcaggct
     1321 ctaggttttg tacgtgaacg ctactcacta gccgatggag accgtgaccg tggtcgcaac
     1381 caacaaaagg tgattgtggc tatccttcaa aaattaacgt caaccgaagc actgaaaaat
     1441 tatagtacga tcattaatag cttgcaagat tctatccaaa caaatatgcc acttgagact
     1501 atgataaatt tggtcaatgc tcagttagaa agtggaggga attataaagt aaattctcaa
     1561 gatttaaaag ggacaggtcg gacggatctt ccttcttatg caatgccaga cagtaacctc
     1621 tatgtgttgg aaatagatga tagtagttta gctgtagtta aagcagctat acaggatgtg
     1681 atggagggta gatgaaatga tagacatcca ttcgcatatc gtttttgatg tagatgacgg
     1741 tcccaagtca agagaggaaa gcaaggctct cttggcagaa tcctacaggc aaggggtacg
     1801 aatcattgtc tctacctctc accgtcgcaa gggcatgttt gaaactccgg aagagaagat
     1861 agcagaaaac tttcttcagg ttcgggaaat agctaaggaa gtggcgagtg acttggtcat
     1921 tgcttacgga gctgaaattt actacacacc agatgttctg gataagctgg aaaaaaagcg
     1981 gattccgacc ctcaatgata gtcgttatgc cttgatagag tttagtatga acactcctta
     2041 tcgcgatatt catagcgcct tgagcaagat cttgatgttg ggaattactc cagtcattgc
     2101 ccacattgag cgctatgatg ctcttgaaaa taatgaaaaa cgcgttcgag aactgatcga
     2161 tatgggctgt tacacgcaag taaatagttc acatgtcctc aaacccaaac tttttggcga
     2221 acgttataaa ttcatgaaaa aaagagctca gtatttttta gagcaggatt tggttcatgt
     2281 cattgcaagt gatatgcaca atctagacgg tagacctcct catatggcag aagcatatga
     2341 ccttgttacc caaaaatacg gagaagcgaa ggctcaggaa ctttttatag acaatcctcg
     2401 aaaaattgta atggatcaac taatttagga gaaatgatga aagaacaaaa cacgatagaa
     2461 atcgatgtat ttcaattatt taaaaccttg tggaaacgca agctaatgat tttaatagtg
     2521 gcacttgtga caggtgcggg ggcttttgca tatagcactt ttattgttaa gccagaatat
     2581 acgagtacca cgcgaattta cgtagtgaat cgcgatcaag gagacaagcc ggggctgaca
     2641 aatcaggatt tgcaggcagg atcttatctg gtaaaagact accgtgagat tatcctttcg
     2701 cagaatgtat tggaaaaagt agcgacaaat ttgaagttgg atatgccaac aaaaacgtta
     2761 gccagcaaag ttaaagtgac tgtaccaact gacactcgta tcgtctcaat ctctgtcaaa
     2821 gataaacaac cagaagaagc cagtcgtatc gctaattctc tacgagaagt tgctgcagaa
     2881 aagatcgtcg ctgtaacgcg agtatctgat gtaacgacac ttgaagaagc gcgaccagct
     2941 acgactccct cttctccaaa tgttcgacgc aattccttgt ttggttttct tggaggagca
     3001 gtcgtaacag taattgctgt tcttttgatt gagttgctcg acacccgtgt gaaacgtcct
     3061 gaagatgtcg aagatgtact gcaaattcca cttttagggg tcgttccaga tttgaacaaa
     3121 atgaaatagg aggaagttat gccaacatta gaaatctcac aggcaaaatt ggattttgta
     3181 aaaaaggcag aggaatatta taacgctttg tgcacgaacc tacagttaag tggagatgat
     3241 ttgaaagtat tttctatcac ttctgtgaaa ctaggagaag gaaaatcaac gacttccacc
     3301 aatatcgctt gggcttttgc gcatgcaggt tacaaaacgc tgctgattga tggagatatt
     3361 cgcaattctg ttatgttagg tgtctttaaa gcaagggata agattacagg cctgacagaa
     3421 tttttatcag gaactacaga cctatcacaa gggctttgtg ataccaatgt cgaaaatctc
     3481 tttgtaattc aggctggctc tgtgtcaccg aatccgacag ctcttcttca aagtaagaat
     3541 ttcagtacaa tgcttgaaac cttgcgtaaa tattttgact acatcattgt agatactgct
     3601 cctgtcggtg tcgtgattga tgcggctatt attacgcgaa aatgcgatgc ttctatttta
     3661 gtgacggagg taggtgaaat aaatcgacgg gatattcaaa aagcaaaaga acagttggaa
     3721 cacacaggaa agccgttttt gggagttgtg ttgaataaat tcgatacttc agtagacaaa
     3781 tacggttctt atggaaatta tggagattac gggaaaaata aaaaataggt cgggggatta
     3841 gagatgaatg gaaaaatagt aaagtcttca ttggccataa tccagagttt tcttgttatt
     3901 ttattgactt atctacttag tgctgtgaga gaagcggaga ttgtttcaac aacagctatt
     3961 gcactttata tcctccatta ttttgtcttt tatatcagtg attatggaca ggatttcttt
     4021 aaaagaggat atttgattga acttgtccag acattgaaat atatcctatt ctttgcacta
     4081 gcgattagta tttctaattt tttcttagag gatcgattta gtatttccag acgaggcatg
     4141 atttactttc tcacattaca tgctctctta gtctatgtgc taaacctatt tatcaagtgg
     4201 tattggaagc gggcttatcc caactttaaa ggaagtaaga agattctcct acttacagca
     4261 acttctcgtg tcgaaaaggt actggataga ttaatagaat caaatgaggt tgttggggag
     4321 ttggtagccg tcagtgtctt agataaacca gattttcagc atgattgttt aaaggtagta
     4381 gcagaggggg agatagtaaa ctttgcgact catgaggtgg tcgatgaagt ctttatcaat
     4441 cttccaagtg aaaaatacaa tattggagag cttgtctctc agtttgaaac gatgggaatt
     4501 gatgtaacag ttaatctaaa tgcttttgat cgtagtttgg cacgtaacaa gcaaattcgt
     4561 gagatggcag gattaaacgt tgtgactttt tctacaacat tttataagac tagtcatgta
     4621 attgctaagc ggattattga tatcatgggt gcattggtag ggctgatact atgtggttta
     4681 gtcagtattg tactggttcc tttgattcga aaggatgggg gctctgctat ttttgctcag
     4741 acgcgtatag gaaaaaatgg tcgtcagttc actttttata agtttcgctc tatgtgtgta
     4801 gatgccgagg cgaaaaaaag agaactcatg gaacaaaata ccatgcaggg tggaatgttt
     4861 aaggtggacg atgatcctcg tatcacgaaa attggttgtt ttatacggaa gactagcttg
     4921 gacgagctac cacagtttta taatgttcta aagggagata tgagtttggt tggcacacgg
     4981 ccaccaacag tggacgagta tgagcactat accccagaac aaaagcgtcg tctgagtttt
     5041 aaacctggca taacagggtt atggcaggtc agcggacgaa gtgagattaa gaattttgat
     5101 gaagttgtca aattagatgt agcctatata gacgattgga caatttggaa agatattgaa
     5161 attttattga agacagttaa agttgtattg atgaaggatg gagcgaagtg atttttgccc
     5221 ttcggtcttg ttaggagaga tatgaaacag tcagtttata tcattggttc aaaggggatt
     5281 cctgccaagt atggaggatt tgaaaccttt gttgagaaat taacagaata tcaaaaagat
     5341 ggtaacatcc aatactatgt tgcttgcatg cgcgaaaatt ctgcaaagtc aggatttaca
     5401 gcagacacat ttgagtacaa cggtgctatt tgttacaaca ttgatgtgcc taatattggt
     5461 cctgctagag ccattgctta cgatattgca gcggtcaata aggctattga attgtctaag
     5521 ggaaacaagg acgaggctcc cattttttac attctagctt gtcgtatcgg accttttatt
     5581 tctggactta agaaaaaaat tcgttcgatc ggaggccgtt tgctggtaaa tccagatggt
     5641 catgagtggc ttcgagctaa atggagcttg ccagttcgga agtattggaa attttcggaa
     5701 cagttgatgg tcaaacatgc agatttatta gtctgcgata gcaaaaatat cgaaaaatat
     5761 attcgagagg actataaaca gtatcagccc aagacgacct atatcgctta tggtacagat
     5821 actacccctt caagtctgaa atcagaagat gccaaagttc gaaactggta tcgtgaaaag
     5881 ggagtaagcg aaaatggcta ttatctagtg gtgggacgat tcgttcccga aaacaactat
     5941 gaaaccatga ttcgtgaatt tatcaagtct aagtccaata aggactttgt ccttattaca
     6001 aatgtggaac agaataaatt ttacgatcag ttgctcaagg aaacaggttt cgacaaggat
     6061 ctaagagtca aatttgtggg aacagtctat gaccaagaat tgctcaagta tatccgtgaa
     6121 aatgctttcg cctatttcca tggacatgaa gttgggggta ccaatccatc gcttcttgaa
     6181 gctttagcat ccactaaact caacttgttg ttggatgtcg gctttaaccg tgaagttggt
     6241 gaagacggag ccatttattg gaaaaaagat gagctagcgc atgtaatcga agaagtggaa
     6301 cgatttgatg aaggtgatat tacggaatta gacgaaaagt ctagccaacg aattgcggat
     6361 gcatttacgt gggaaaagat tgtgtcagat tatgaggaag tgtttactgt atgaaaattt
     6421 tgcattatac tttaggcttt caaccatcac gtacaggtgg tcttgtcaag tatgctgagg
     6481 atttgatgac tcaacaagct acagatggac atgaagtaat cgcattatat ccaggagaaa
     6541 tctcaattat atttaggcag gttagaataa aaaaagcaga gaatcgaaaa ttccaatgct
     6601 ataaaataat aaacagccta cccttggctc tatttggtgg tatttcagaa ccagatgaat
     6661 ttatgaagag ttgtgataaa gcttcttata ggaaattttt gaaaaatatt aaggtagatg
     6721 taattcacat tcactcgctt ataggattac ataaggaatt tattgaagtt gcaaaagaat
     6781 taggaattaa aactgtattt acaagccatg attattatgg tttagcgcca gttccgcatt
     6841 tttattttaa cggagtagat tatagtagta ataatactaa tttagcatgg aacatcatgt
     6901 cctctaatgc tcttagtgta aaaaaacttc gattctttca agtctctttt tacccaacaa
     6961 ttcggaaatt gatgaaaatg cttgggaaaa atccaaagtc caagaaaaac ttagtaattc
     7021 gtgatatcac ggaggctatt gattatagtg ctctccgctc ttattataaa gcaatgtttg
     7081 ggttaataga tgcttacctt ttcaatagtc agttagctaa ggaagtttat gaagctaatc
     7141 atataatacc taaaaacaat atcatagtgt ccatttctaa cagctcaata agtaatcata
     7201 atattcgtgt tagttccggt gagaaaacag tggtagctta tattgggcct gatgaggaat
     7261 ataaggggta ttttgatttt ctagatatag ttaatgattt agatcaggaa aagtatgata
     7321 ttaaaacata tggacatttt ccaaatgaag attgtccacc ttatatccaa cagaacggtt
     7381 atttcacaaa agacacggtt ggaagcgttt attccaatat agatattttg attgtgccga
     7441 gtaggtggaa ggaaacattt ggtttgatta gtatagaggc gctatcgtat gatgtgaatg
     7501 tttttgtgag caaaaatgtg ggctctaaag atttggtttc agaagaacat atctttcata
     7561 ataaagacga tttgttaaaa aaaattcaat atgtaaaatt cgagaatgta aaattcaaaa
     7621 cgatgaaaga gcatatggtg gagattataa attactatga aaggattaca aatgataatc
     7681 aaaagattaa ttaagacaat tacaggtaaa gaaattgatc ttcaccctga tatcccaata
     7741 acttacattc ttcagagagg ttttcaatac ggtttgggtc ttagtcgagg gttgttacgt
     7801 ggtattggtc taggaaaaaa aggcaaacga ttatttattg gacgtggggt aacccttctc
     7861 gcaaaacgca agttatatgt tggaaacaat atccgaatcg gcaaatatgt gagcatagat
     7921 tgcctttcaa aggatgggat ccaaattgcg gataatgtta agataggaga ttactcgcaa
     7981 ataattggta caggttcagt aaaaaatatg ggtattgggc tcaaaattgg aaagaactct
     8041 tctttctcag aatatagttt attcggttct gcaggtggga ttactatcgg aggagatgtt
     8101 attgctggac aaaatgtacg ttttcatgct gagaatcata gctacgaagt gttgcatata
     8161 ccaatcagag agcaaggtgt taatcgtaaa gggatatccg ttggtgacaa ttgctggatt
     8221 ggggcaggag ctgttttttt agatggatct agtatcggtt caggttgtat cgttgcaacg
     8281 aatgcggttg ttactaagaa atttccagat aatgtaatta ttggtggagt gccagctaaa
     8341 attttaatgg aaagaaagta gtattaaatt aattgtataa atggagggaa atgatatgtc
     8401 taaaatgaag attgctgtag ttgggacagg ttatgttggt ttatccattt ctgtgttact
     8461 tgcacaacac catcatgtag tagcagtaga tattgtaaaa gagaaagtag aattaattaa
     8521 taaaagaatt tcacctattc aggatgattt tattgaaaga tatctttcag aaagtaattt
     8581 agatttagtt gcaacaatag acgctgaaac agcttataaa gatgcctctt ttatcgtagt
     8641 agcgacacca acaaattatg acttagaaag aaattttttt gatacatcaa cagttgaatc
     8701 ggtcattcaa caagttcaga atatgaattc tacagcaact atagtaataa aatcaacagt
     8761 ccccgtgggc tttaccgatt caattcgtaa aaaattagga atttcaaatc ttctattcag
     8821 tcctgaattt ttgcgtgaat caagggcact ttatgataac ttatatccaa gtcggatcat
     8881 agttggaaca gatttaagta atcaaaaatt agttgaaaaa gcccaagttt tctctaatct
     8941 tttagtgcaa ggtgccatta aaaaagatat ccctatttta actatgggat ttactgaagc
     9001 tgaagcagtt aaattatttg ctaataccta cttagcattg cgggtatcat attttaatga
     9061 attagatact tatgcagaga tcaaagggtt agatactcaa aaaataattg aaggtgttag
     9121 tttagatcct cgtatcggaa cccattataa taatccgagc tttgggtatg gtggatattg
     9181 cttaccaaag gatactaagc aacttttagc caattataag aatgtcccag aagagcttat
     9241 tggagctata gtacgaagca atacaacacg taaagatttt attgctaatc aagttcttaa
     9301 agtggtgaat tataatatac cagaagacga tattcctact aaacagatgg agaaagaagt
     9361 tgttattgga atataccgat taactatgaa aagtaacagt gataactttc gtcagagttc
     9421 aatacaagga gttatgaaac gtattaagga tagaggagtt aaagtaatca tttttgagcc
     9481 tactctaaaa gatagtgata cattctttgg aaacgctgtt ataaatgatt tagaagagtt
     9541 caaagtaaag tgtgatgtga ttattgcaaa tcgttatgat gaaacgttga atgacgttaa
     9601 ggataaagta tatacacgag atatttttag aagagattga taaaaatatg aaaaaagtat
     9661 taattgttcg aagtggacct taccaagtca atccggaagg atataatctt caagaacttg
     9721 gtttagcctc cgctatcagt cagcaaggct accagtgtga tgtcatgtat tatcacaaaa
     9781 caaagaacta tgatcaatta tatgagaaaa atggggaaca aattaaaata ttctggagga
     9841 ggggaataag attatttaga agtggaattt atccccagat tttaagagag aaatttttga
     9901 atcagtatga taagataatt atttctgagt acagccagat tatggcagtt ttattgtcta
     9961 gaattcattc caatgtatat atttataatg gcccatacta taatctattt aagattccca
    10021 ttattgaacc tatatacgat tttctttttg tagaaatgct caataagaga accaaaacag
    10081 ttttctgcaa gacagaaaaa gcagagtgtt atcttaaaaa caaaggattc aatgattgta
    10141 aagtagtggg cgtaggtcta gatattgaga agtttgaaca agaagaggaa cctacagagg
    10201 atactataga gcttttaaga agaatggaga ataaacaaaa tattctttat gtaggttcac
    10261 tatcaaaaag aaaaaacaca gctcagttaa ttagaatttt taatatttta aaatctaaaa
    10321 gtggtaagaa aaatgaactt caattggtat tgattggtaa ggatgaggat aatattgttg
    10381 aaaaaattaa ctattcacgg tttaaagatg atattattta tcaaccttat ttaaagaatt
    10441 ctcagcttca atttatttac ccatcatcac aactacttgt gctcccgtca gttcaagaga
    10501 tttttggtat ggtattactt gaggcaatgt attttaagtt gcctgttgtt tccagtgcaa
    10561 gtgctggagg agagacactg attcaagatg gtataaacgg taaaattgtg aatgatttta
    10621 atgatgaaca ctgggtggat tgtatagaaa atctattaaa taacccattg gaattgaaac
    10681 ggcttggaga atgtgctcat aagcgcatta cggaacagtt tatgtggtct tcaattgcga
    10741 gaaaaataat tgagacattt gatgaaaggt aagacttgct atgaattttt gttttgtgat
    10801 tttgcattat cgtaccagca atgacactat agagtgtatc aaatcgattc aaaagcttga
    10861 gggagattat aaaattgtaa ttgttgataa tgcttctcaa aatggcagta tagaaagggt
    10921 agaagcctta tttgcaaata atgacgagat agttataata aaaaacacga aaaacttagg
    10981 atttgctgct ggaaataata ttggatacgc ctacgctagg actcaaataa aagctgatat
    11041 gattgctgta cttaataatg atattgttat taagcaaaaa gatttcatca atcgtatatt
    11101 tgaactctat agaaattctc agtttcatat cgctggtcca gacattgtct ctcttgtaga
    11161 tggtcatcat caaagtcctg ttgttgagaa gattaattct atatctaagg ctaataaaga
    11221 actttttaaa tatagaatct tgaggattat taataaaata ggattatatg agctgatgac
    11281 tagacagcca aaaaaagaat taaatagaat aagtgttgca gaccctatga gatatcagga
    11341 aaatgttatt ttacatggga gttttgtaat tttttcaccg ttgtatgttt cagaggagga
    11401 gtgtgctttc agaccggata cattcatgta tatggaagag cctattctat atgaatattg
    11461 catgcttaaa aattataaga cagtatttga tccttctatt gtaatttatc ataaagagga
    11521 ctcatcaaca aattcgttgt ataatgcagc atatgcaaaa agagagtttg tttttaaaaa
    11581 tatgattaga tctctaaaga tttatagaag tctattgaag tagtaaacta aggaaaggat
    11641 aataattaga aattgaatct tagtatgtta gccttgacaa taggaacagt ggtatttgtt
    11701 aaaaaaacgt ataggacgtt tctcaatccc ataattttat ttgtaatttt gtggtttatt
    11761 ataacaactt tgtcaagttt aaaactattc caacttttcg agattagtac tcacacacaa
    11821 caaattattt tgcttgggac ttctctattt gttatagggg gagggatagc aatttggttt
    11881 cgggataaat tttattttaa agttggcggt aactcatatt ttacaacaga ctttgaaatt
    11941 aattataatt tgttcttttt gctaggtatc atttgccttt tctattattt gccagatttc
    12001 ttttcctcac tggtatcatt aataagaggt gggaatttaa acttagttag acaatctgcg
    12061 caggatgcag tagataccag tggattaaag aatttcattg gaacatttat tgttagtcct
    12121 agtgccatgg tattagaaat attaggagta ttagatttct ggagcaataa aaaaggtaga
    12181 aaactatttt atcttagttt agctgtcatt tttgtaagag ttattgcaga tgctggtaga
    12241 acacctctat ttaatgttgt catatattta ttacttactg ttttagcaaa taggttctct
    12301 gaaaaaactg aaaagaagag aaaagttagt aaaattaaga tagtaaatta tggtatgcta
    12361 ggttcaatta tcttatggct atcaacttta tctaggacaa caacctccgt ttataggatt
    12421 ctttattttt atttcgcaat gtccccaata ttattagaaa agtggagtag tgtacttgat
    12481 tctgaaaaat tagtaacaaa gggtttggtt tcgttgaacg gtttcttttt ttcaatctca
    12541 tatgtactta aaaatctgtt tagaatagat tattcgcaaa gagtattaga agcatacaca
    12601 atgattgcga atactgatgc aatctggtat aatattgcac ctggtttgac caaggcaaat
    12661 gcatatgtct ctctgttttg gttcttttat gcggatggac gtttactagg agttttaata
    12721 ggatcccttc tatatggtac cttttgtggt tatatctttt gcaggtatat ccagcaacaa
    12781 aataaaaaga atttggctat gttactattt atttatcaag gtgttttttt ctcttttatt
    12841 agatttccgt tttcaaaatc aaattatgca attgcattcg tactcttatt attttttgct
    12901 tttaagaaga aaggaataga gaaaagtgtt taatatcaat gaccagtcta ttatttatgt
    12961 tgcatgtcct tattttaata aaacaggtgg aacggagctt gtccatcaat tagtttattc
    13021 tattaatcat tttgggggga aagctatcgt tgcttattat ggtagtgaaa gtgctccaaa
    13081 taaggtgaat cctgcgttta gagaatatgt ttctacgttt gttgatataa aagatgttat
    13141 tgactctctt gataatatta ttattttacc ggaaattaat ccggatttag ctgctaatct
    13201 agagtctatt caaaaagcag tatggtggat gagcgttgac aattatttga agcgtaatgg
    13261 tattttaggt tccttggaac attttggact tttacgaaca attaaattat ttgtaaaagg
    13321 aaatattaaa ataggtggat atagaataga taaagagatt ccccatcttt atcaaagtga
    13381 atacgccaag caatttcttc tagctaaagg tgtcaaaaag tactatagat tgtctgatta
    13441 tttaaacgag tcttatattc agcgatctat ttcaacagac actaaaaaag atgttattct
    13501 ttacaatcct aaaaaaggga ttgaatttac tcgtgagcta attaaacagg ctccagaatt
    13561 aacgttctct ccaattgaga atatgtcaac tgaacaggtg aaaaaattac tttcaaaaag
    13621 caaagtatat attgattttg gcaaccatcc tgggaaagat agattcccac gggaggcagc
    13681 gatatcaggt tgttgtgtga taactgggaa acgaggttct gcaaaatatt ataaggatat
    13741 tcctattcca gattcataca aatttgaaga cactgttgaa aatatcccca acattattga
    13801 gaccctgaaa tcatgcttaa aaaattatga caaacatact gttgactttg agaaatatca
    13861 acaatatatt aaatctgaac atgatttatt tgaaagagat gtgaaagaat tattcactag
    13921 gaataggggt taaggttatg tcaaccagaa attcacttat taaaaattct ctttataatg
    13981 ttgcttatag aatgttaaat atcatatttc cattagtatc cgcaacatat actgcacgga
    14041 taattttagc tagtggagtt ggggaggtct cgtttgcaca aaatgttgtt tcttacttta
    14101 caacgatagc tgctatgggt attccaaatt atggtatacg agaaattgct aaaactagaa
    14161 ataaagcaga ggctacgaat aaagtttttt cagagctatt tctgattaat ggattgtcta
    14221 cattactgtg ttctatagta tatttaattc tgattttgac attcaatagc atttttgata
    14281 atacatcaat gtatcttgct gtgggtttaa cattagtgtt taacttcctt aatatcgatt
    14341 ggttctatca aggaaaagag gactatgcat acatcacgaa acgtagtttc agtataaaac
    14401 ttatttctct ttttagttta tttatttttg ttagagatac tgacgatgca gttaactatg
    14461 cattgatttc tagcttagca attggcggga ataatatttt taatcttgtt
//
LOCUS       DBEJKC010000048        14259 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.048, whole genome shotgun sequence.
ACCESSION   DBEJKC010000048 DBEJKC010000000
VERSION     DBEJKC010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14259
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.048"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..93)
                     /locus_tag="ACL3G6_001572"
     CDS             complement(<1..93)
                     /locus_tag="ACL3G6_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR0546074.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCL"
     gene            complement(86..610)
                     /locus_tag="ACL3G6_001573"
     CDS             complement(86..610)
                     /locus_tag="ACL3G6_001573"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR0546075.1"
                     /translation="MDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICH
                     LKCRDNFRLLGEIYPATIVYQISDLLYIPSDTEGIPMCVLESMSQGTPVLASNVGGLS
                     EIIEHRVDGFLFEKEDVEGVCACANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVET
                     MRVYDELLEKSSHG"
     gene            complement(738..1292)
                     /locus_tag="ACL3G6_001574"
     CDS             complement(738..1292)
                     /locus_tag="ACL3G6_001574"
                     /inference="COORDINATES: protein motif:HMM:NF024831.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR0546076.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKIQLIHCHGYSTNYFLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWT
                     YSMGDAFICVSETMKKRLESIIKK"
     gene            1535..2226
                     /locus_tag="ACL3G6_001575"
                     /pseudo
     CDS             1535..2226
                     /locus_tag="ACL3G6_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2562..3868
                     /locus_tag="ACL3G6_001576"
                     /pseudo
     CDS             2562..3868
                     /locus_tag="ACL3G6_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(3908..4918)
                     /gene="tsaD"
                     /locus_tag="ACL3G6_001577"
     CDS             complement(3908..4918)
                     /gene="tsaD"
                     /locus_tag="ACL3G6_001577"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HGR0546077.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(4908..5345)
                     /gene="rimI"
                     /locus_tag="ACL3G6_001578"
     CDS             complement(4908..5345)
                     /gene="rimI"
                     /locus_tag="ACL3G6_001578"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HGR0546078.1"
                     /translation="MIEIKRIQQQPDLAKAIYAVMIAVYPVSPWTLEQIQADLFQDQT
                     WYALAYDGAEVIGFLAVQETLFEAEVLQIAVKGAYQGKGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIADRKAYYHDPVEDAIIMKREIDEG"
     gene            complement(5342..6025)
                     /gene="tsaB"
                     /locus_tag="ACL3G6_001579"
     CDS             complement(5342..6025)
                     /gene="tsaB"
                     /locus_tag="ACL3G6_001579"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HGR0546079.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPY
                     QQEGLVVPIMDARRNNVYAGFYENAKPVLPEAHLSFAEVLEQVKDAEQVTFVGEVGAF
                     VEQIQEQLPQASYQETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            6203..6388
                     /gene="cibA"
                     /locus_tag="ACL3G6_001580"
     CDS             6203..6388
                     /gene="cibA"
                     /locus_tag="ACL3G6_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HGR0546080.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            6390..6542
                     /gene="cibB"
                     /locus_tag="ACL3G6_001581"
     CDS             6390..6542
                     /gene="cibB"
                     /locus_tag="ACL3G6_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HGR0546081.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(6865..7080)
                     /locus_tag="ACL3G6_001582"
                     /pseudo
     CDS             complement(6865..7080)
                     /locus_tag="ACL3G6_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            7360..7593
                     /locus_tag="ACL3G6_001583"
     CDS             7360..7593
                     /locus_tag="ACL3G6_001583"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase subunit epsilon"
                     /protein_id="HGR0546082.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            7595..9274
                     /locus_tag="ACL3G6_001584"
     CDS             7595..9274
                     /locus_tag="ACL3G6_001584"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGR0546083.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(9469..11382)
                     /gene="mnmG"
                     /locus_tag="ACL3G6_001585"
     CDS             complement(9469..11382)
                     /gene="mnmG"
                     /locus_tag="ACL3G6_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HGR0546084.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWASFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(11392..11847)
                     /locus_tag="ACL3G6_001586"
     CDS             complement(11392..11847)
                     /locus_tag="ACL3G6_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0546085.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYIIGGA
                     IQVNEKTEDAVVREVKEELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            complement(11988..13109)
                     /gene="mnmA"
                     /locus_tag="ACL3G6_001587"
     CDS             complement(11988..13109)
                     /gene="mnmA"
                     /locus_tag="ACL3G6_001587"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HGR0546086.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLKKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            complement(13510..>14259)
                     /locus_tag="ACL3G6_001588"
     CDS             complement(13510..>14259)
                     /locus_tag="ACL3G6_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HGR0546087.1"
                     /translation="EAPAPAPKPAPAPKPAPAPKPAPAPKPETPKTGWKQENGMWYFY
                     NTDGSMATGWLQNNGSWYYLNANGAMATGWAKVNGLWYYLNSNGAMATGWLQYNDSWY
                     YLNTNGAMATGWLEYNGSWYYLNANGAMATGWLEYNGSWYYLNSNGAMATGWLQYNGS
                     WYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYYLEASGAMKANQWFKV
                     SDKWYYVNGLGALAVNTTVDGYTVNENGEWV"
BASE COUNT         4088 a         3286 c         2733 g         4152 t
ORIGIN      
        1 taaacaactt ttcacagctc taatcagaga ttcataccta ttatgtgttg gtattataat
       61 acttactaat tcttgatcta tattcctatc catgactact cttctctaat aattcatcat
      121 atactctcat ggtttctaca aacatttttt gcacagaaaa atgttttctt atttttgatt
      181 tactattctc acctatatat ttcaaatact cagaatcatt gagtaaaaaa ttagcacaag
      241 cacacactcc ctcaacatct tccttctcaa ataaaaatcc atcaacccta tgttcaataa
      301 tttcacttaa cccgccaaca ttactagcta aaaccggagt tccttgtgac attgactcta
      361 aaacacacat aggtattcct tctgtatcag aaggaatata caataaatcc gatatttggt
      421 aaactatagt agctggatag atttcaccaa gtaacctgaa attatctcta catttcaaat
      481 ggcaaatttt ttctttcaaa gcagcccaca tactaccatt tccagccata ataaaaatca
      541 catcttctct gactaaaaat aatttttctg caaattcaag gaatctatcc ggcctttttt
      601 ctggatccaa ccttccaaca taacaaatga tttttttgtt atttggaata caaaattctt
      661 ttttaaagtc ttgaacacct actacatcta aatcgctatt tgatacatta attccgttat
      721 ttattgcaac tatcttctta tttttttatt atactctcca atcttttttt catagtttca
      781 gatacacaaa taaaagcatc tcccatagaa tatgtccaaa aatcaaaata agtcaagaat
      841 ttctttttta agttatattc aacccatcca tggcatgtta tcactgtctt aacctttcca
      901 aatccattct tgtcaagttt ttttaacata tataaaaaat aattagttga gtagccatga
      961 cagtgtataa gttggatttt taataatttt aaaatatttt taacgtgtaa ggcagtttca
     1021 aaattatttg aacattgagt acaatcaaca taggcaatat ctaaattttt ataatcatca
     1081 ataacctttg aatctctaga tacgattatc aaaataggat atagagacat ccttctgatc
     1141 tgctttttac aaagtccaat tatatgcgga tctatacctc cacaatgtcc attattatac
     1201 ctaactataa tatgagccga aaacactata tccttaatgt ctccatatcc atcagggata
     1261 ttaatattta tttttccaca actatattgc attgtaacca tctccttaaa cgacgcatta
     1321 tgatatttga tagagaaatt tttatgaata actcaataat tttatagtaa atcatgctta
     1381 tatctcaaag atacctattt tctcttgtct cgaccttctc caaagaattg ctataatact
     1441 attacaaata catctgcact acacttcaaa ttttagcact gtataaaaac gtttcaacac
     1501 actaacttta agaaaacttc cactattaat tgaaaaagtt gatagagata aattaaagat
     1561 ctatattgaa actcatcccg atgcttattt gactgaaata gctgctgaat tcaactgtcc
     1621 tccaacaact attcattacg ctctaaaggc tatgggatat agtctaaaaa agagctgtac
     1681 ctactgcgaa caagacccag aaaaagtaaa tcggttcctt aaagaattga atcacttaag
     1741 ctacctgact cctatttata tttatgagac aggggttgag acctattttt atctcgaata
     1801 tgatcgagcc ttgagcaggc agttagtctc tctggaagaa gatataatta tttgaattaa
     1861 gatcgagaca acgcacacca gagattgcga tactgttata gaagtactaa tgcccttttt
     1921 tgtttcaata tactatggct ccgatgacct ataaagatac gatgacgagt gactttttcg
     1981 aagcttgctt ccaaaaattc ttactaccta ctttagatac accatccctt atcattatgg
     2041 acaatgcaag gtttcacaga atgaacatgt gtaaggagca gggcatagac tgttaccact
     2101 tcctacctat tcacccgagt ataatcccat tgagaaaata tgggcttaca tcaaaaacat
     2161 ctcagaataa tattgtcaaa ttacgatgct tttcttgagg cacttttgtc ctattcttgt
     2221 ttcagccgac tatactccgt tattgggcag ctacggaaca gtcgatggga cgatgggggg
     2281 acataaaaaa atcctccagt tttgtttttt ataacagtat actggagaat tgacaatctc
     2341 ggtagatacc tcgttatagc gcggttactt attaggcagt tacaaaacaa ctgtgaacag
     2401 aaaacattcc agagtcagac aagactttgg aatgttttgg ctctataatt tctgtagtgg
     2461 gtaatcccac cccaggaatt atagggtcgt ttcttgtaga aaaaaagccc catatgacct
     2521 ataatgaaaa gcgtctaacc aactcattag aaagggttca tatggaacaa cttaagaata
     2581 ccacagattt gctcggattg aaagacaaaa atatcaaaat cttgtctgtt ctgaaatacc
     2641 aaacccatct agtcgttcag gcaaagttgg attcccccgc tcctccttgt cctcattgtc
     2701 aagggaagat gatcaaatac gacttccaga aagcctctaa aattccgctt ctcgactgtc
     2761 agggtttacc cacggtacta catctcaaaa agcgccgctt tcagtgcaag aattgcctta
     2821 aggtggtcgt ttctcaaaca tccattgtca agaaaaattg ccagatttcc aacatggtga
     2881 gacaaaaaat cgctcagctc ctccttgaaa agcagtctat gactgagatt gcccacagat
     2941 tggcggtctc aacttccacc gtcatccgaa aactgaggga atttaagttt gaaaccgatt
     3001 ggaccaagtt gccaaaagtt atgagttggg atgagtatag cttcaaaaag agcaaaatga
     3061 gcttcattgc ccaagatttt gagtccaaat ccatcctcgc aattttagac gggcgaactc
     3121 atgcggtgat tcgaaaccat ttccaacgct atcagagaga ggttcgggag ctggtcgagg
     3181 tcatcaccat ggacatgtac agcccttatt atcggctcgc taagcaactc tttccgaagg
     3241 cgaagattgt tcttgaccgc ttccacattg tccaacatct gagccgagct atgaaccgag
     3301 tacgaatcca aatcatgaac caatttgacc gaaaatcctt ggagtatcgg gcgctcaagc
     3361 gcttttggaa ccctcgcttt ttcgtttcta ggctcgggct aaatcagtcc actggactga
     3421 tttactacac caggatagct tcaagctctg tcagaaacga ttctatcagc ccacgtttcg
     3481 aatgcactta acccatcggg aagtacgaga taagctgctt tcttactctg agggattaca
     3541 ggttcactac gaactctatc aactcctgct ctttcatttt caagagaaga atgccgacca
     3601 tttctttgga ttgattgagc aagaactgcc aacggttcat ccgctttttc aaacggtctt
     3661 ttggactttt ttaagggata gagataagat tatcaacgca cttaagctgc cttattccaa
     3721 cgctaaactt gaagcgacca ataatttgat taaggttatc aagcgcaaag cctttggttt
     3781 ccggaacttt aacaatttta aaaaacggat tttgatgact ttgaacatca aaaaagagag
     3841 tacgaatttc gtactctcca gattgtagct tttcgcctac ccactacact tgacaaagag
     3901 ccactcttta ttccatggta tcaaaggcaa gacttggttt ggcattgagg tcccagcctg
     3961 cgaagttttc tttgttccac tcgctgacgc tggcataggc aatcatacct gcattgtctc
     4021 cgcagagtcg cagagggggg atgataacct tgacatctgt gatttcggct gctaggcgtt
     4081 ctctgagacc tttattggct gccacaccac ctgccacaac tagggtttta acaggatatt
     4141 tctccaaagc cttcttggtt tttgccatga gaatgtccat aactgctgct tggaaggaag
     4201 cacacaaatc ttctgtagac aggctttctc ccttttgctc ggcattgtga tgaagattga
     4261 taaaggcaga tttcaaacct gagaaggaga actccagatt atcttcctta atcatggcac
     4321 gggggaaatc ataaatatcc tgcccctgat gagccagctc gtcaatctca cgacctgcag
     4381 gataggtcaa gcccatgaca cgaccgacct tgtcataagc ctccccaact gcatcgtctc
     4441 gtgtctcccc aacaatcttg taatctcctg cctccgaaac atagaccaac tctgtgtgcc
     4501 caccgctaac caagagggct agcaagggaa actccaaagg ctccacactc tgagctgcca
     4561 tgaggtgccc agccatgtga ttaacaggaa tcagtggaag tccgtgagcc caagcaaagg
     4621 ccttggcagc tgacaaacca actagcaagg ctccgaccaa gcctggtccg taggtaaccg
     4681 caacagctgt cacatcctct tcggtaatcc ctgcttctgc caatgcctcc tcgatacagg
     4741 ctgtaatgac ctcgacatgg tgacgactgg ctacttcggg cactacgcca ccaaaacgtt
     4801 tgtgactctc aatttgacta gcaatgacat tggacaagag ctcatcgtcg tttttcaaga
     4861 cggcgacact ggtctcatca caggatgtct caaatgctaa aatatatcta tccttcatct
     4921 atttctctct tcatgataat ggcgtcctcg actgggtcat ggtagtaggc ctttcgatca
     4981 gcgatgaccg ccattttttc tttcttgtaa aatgcttgcg ctcgttgatt tgactttctg
     5041 acttcgagga aaatctcctt atctgtcggc aattgagcaa acaaggctga cgcaatgccc
     5101 ttaccctgat aggctccttt gacagcgatt tgcaggactt ctgcttcaaa gagagtctcc
     5161 tgaacagcta gaaagccaat cacttctgcc ccatcataag ccagagcata ccaagtctgg
     5221 tcttggaaca ggtcagcttg gatttgttcc agcgtccaag gactgactgg gtaaacagct
     5281 atcataacag cgtagatggc tttagctaga tcaggctgct gttggattcg tttgatttct
     5341 atcataggcg tttaatgtaa gactcgccag actcggtatg gttcttgagc cagttttcct
     5401 cagcctcgac acgcttgagg taatttggca caaagtcgtg caaggagtct gcttctttgt
     5461 cccaagccca aagagctaga ttagctgcat ttggcaaggt ttcttggtag ctggcttgtg
     5521 gtagttgttc ttggatctgt tccacaaagg ctccaacttc tccgacaaag gtcacctgct
     5581 cagcatcctt gacctgctct agcacttccg caaaagacag atgcgcttct ggcaagactg
     5641 gcttggcatt ttcataaaag cctgcataga cattgttgcg acgcgcatcc atgataggaa
     5701 ccaccaagcc ttcttgttga tatggcacta gagccaagag actagacata ccaaccaact
     5761 caatgttcag ggtgtaagct aaggtcttag cagttgctac cgcaattcgc aagcctgtat
     5821 agctacccgg cccttcagct accacgattc ggtccaaatc cttgggtgtc caatccaaac
     5881 ttgccatcaa aaaatcgatg gcaggcataa gagtaatact gtgatttttc ttaatattaa
     5941 tcgtcgtctc ggcaagaacc tgcttatcct ctaaaatagc cagagaaaga gccttgctgg
     6001 acgtatcaaa agctaatact ttcataacac attcctatct ttttgtctgc ttactattat
     6061 actacaaaag ctggcacatg ggaattttct ttgcccccag acaagagtgc cctcacttaa
     6121 ctaaaaataa tttaaaaaaa tgctcacttt tccttttctt ttccgaatat aaaagtgaac
     6181 aagaaaaaag gaggaaagtt caatgacaaa ttttgacatt cttgacaatc aatttttatc
     6241 cttatctgaa aatgaattat cagatattga tggcggtctc gctcccttgg ttatctttgg
     6301 agtagcagta tcttggaagg ctattgcagg tggaacagca cttataggtt ctggtttggc
     6361 agctggttat tttttaggag gagattaata tgatgaaaga tttgaacaat tatcgtgaaa
     6421 tttctaataa ggaattgcaa gaaatcaagg gtggctttgg tgtcggtgtt ggtatcgctt
     6481 tatttatggc aggttatacc attggaaaag accttcgtaa aaagtttggt aagtcatgct
     6541 agataagaaa cacattttta gaaggataaa ttttattgtc ttcatctctt acagtttgct
     6601 cagcattctc aatgatttga acattactac catcccttta ccattcgatt tatctgtttg
     6661 tattgtttta tttttatgct tcaactctat ttttgagtag aacaatgact cccataaaaa
     6721 taataagctt tgaaaattcc attgtcatgt catgttagaa aaatgcaaag accacctcat
     6781 cttgatagat ggggtggaat tttcgtgtcg taaatctact atctctacat tcccaaacaa
     6841 aaaaaaccag cataagcagg gcatctaagc atttaatcca aagtaaaata caaaccaaac
     6901 gacataggtc acgaggagga gaaaaagcga gtagagagtc acaaaggtaa ttttccacaa
     6961 gaacttggtt tgtcatcgtt ccagtttggc aaatagaaga tttcctccat aaacgcaagc
     7021 aacaaaaacg ataaaagcta gcaaacgaac tccgatagca aaagcaaata agttatacat
     7081 agggcaacct ccttgactta aaatctatat ggaattatga caagtaataa acttcacttc
     7141 cgttatcaac ataacacatt ttctttattt ttgcaaacga ttaccaaaga aatcgccccc
     7201 taactttctc gtttccgtct tttactaatt tttcattttg tggtataatt gaaataattg
     7261 taacgaatca aggtcaatct agacacaaaa tggaatgaaa tcaagcaaat atctgctaaa
     7321 agtttggaat aagctgacct gtaaatagaa aggaactata tgatttacaa agttttttat
     7381 caagaaacaa aagaacgtag cccacgccgt gaaacaacac gcgcgcttta cctagacatc
     7441 gatgccagct cagaacttga gggtcgcatc actgctcgcc aacttgtcga agaaaatcgc
     7501 ccagagtaca atatcgaata tatcgaactc ttgtctgaca aattgctcga ttacgaaaaa
     7561 gaaactggcg ccttcgaaat cacggagttc taatatggcc tacactctta aacctgaaga
     7621 agtcggcgtt tttgccatcg gtggtctagg agaaatcggg aaaaacactt acggaattga
     7681 ataccaagac gagattatca tcgtcgatgc tgggattaaa ttcccagaag atgacttgct
     7741 tggtatcgac tatgtcattc ctgactactc ttacatcgta gacaatatcg accgcgtcaa
     7801 ggctgtttta atcacacacg gacacgagga ccacattggt gggattccgt tcctactcaa
     7861 gcaagcaaat gtccctattt atgctggacc gcttgccttg gctttgatcc gtgggaaact
     7921 cgaagaacac ggcctcttgc gcaacgccaa actttacgaa atcaaccaca acaccgagtt
     7981 gacctttaaa aatctcaagg caactttctt tagaacgact cactctattc cagagccttt
     8041 ggggattgtc attcatactc ctcaagggaa aatcgtctgt acgggtgact ttaagttcga
     8101 ctttactcca gttggagaac ctgcggactt gcatcgtatg gctgcgcttg gtgaagaagg
     8161 cgtgctctgt ctcctgtctg actcgacaaa tgcggaagta ccaaccttta ccaactctga
     8221 aaaagtcgtt ggtcagtcca ttatgaagat tatccaaggt attgaaggac gtatcatctt
     8281 tgcatccttt gcctcaaata tcttccgtct ccagcaggca acagaagctg ctgttaagac
     8341 tggacgcaag attgcggtct ttggtcgttc tatggaaaag gccattgtca acggaatcga
     8401 tcttggctac atcaaagctc ctaagggaac ctttatcgag ccaaatgaaa tcaaagatta
     8461 tcctgcagga gaagttctta tcctctgtac aggtagtcag ggtgagccta tggcagccct
     8521 ctctcgtatc gccaacggaa cccaccgtca agtacaatta caaccaggtg ataccgttat
     8581 cttctcttct agtcccatcc ctggaaacac tactagcgtc aacaagctga ttaacatcat
     8641 ttctgaagct ggtgtcgaag ttatccacgg taaagtgaac aatatccata catctggaca
     8701 cggtggtcag caagagcaaa aactcatgct ctgcttgatt aagccaaaat acttcatgcc
     8761 tgtccacggt gaataccgca tgcaaaaagt ccacgctgga ctagcagtgg atactggtgt
     8821 tgagaaggac aatatcttta tcatgagcaa tggcgatgtg cttgccctta ctgctgactc
     8881 agctcgtatc gcaggtcatt tcaacgccca agatatctat gtcgatggaa atcgtatcgg
     8941 tgaaattggc gcagctgtcc tcaaagatcg tcgcgatcta tctgaagacg gtgtcgttct
     9001 ggcagtcgca actgttgact tcaaatcgca gatgattcta tctggtccag acatcctcag
     9061 ccgaggcttt gtctacatga gagagtctgg cgacttgatt cgccaaagcc agcgtatcct
     9121 cttcaatgcc attcgtatcg cactgaaaaa taaggatgct agcgtgcaat ctgtcaatgg
     9181 tgccattgtc aacgctattc gccccttcct ctatgaaaat accgaacgtg aaccgatcat
     9241 catcccgatg atcctcacac cagatgaaga ataaagcaag aaaacagccc cgtcttcgga
     9301 gctgtttttc tctatgcttt cttttgagat taaaactcaa tgaaaatcag accagaaggc
     9361 taggaaaatg cataacttga gttagctccc atagttcggg gaactatggg aggttggaga
     9421 tgaatcaaag ccaagctttg aactcattcg taagaagccg acgacgtatc attttgattt
     9481 ttgaagagtt ttagaaatac tacgattttt accttccaga tacaccatca aaatagaaat
     9541 atctgctggg tttactcccg aaatacggct ggcttggccg atggtttctg gattgatgag
     9601 tttgaacttc tgacgagctt ccgtcgcaat agaatcgatg tcatcccagt cgatattggc
     9661 tggaatgcgt ttttcttcca tacgtttcat cttggcaacc tgatccatgg ctttggaaat
     9721 atagccttcg tacttgattt ctgtttcaat caattcgata atcttgtcat ccaagtcttc
     9781 tgcagctggt ccgatgaagg ccaccacatc ttggtaagaa acttctggac ggcgaaggaa
     9841 ttccttggct gtcaccgcat ctgtcaacgg cttgaagccc atttcctcaa ccttagcatt
     9901 ggtttccttg actggcttga gtttgatact gtctaggcgt ttcatctcat tatcaaattg
     9961 atttttcttg atttcaaaac tagcccagcg ttcatcatcc acaaggccaa tctcgcgtcc
    10021 catctcagtc aagcgcatat cagcattgtc atgacgaaga atgagacggt attcagcacg
    10081 acttgtcaag agacggtagg gttcaatggt tcccttggtc accaagtcgt cgatcatcac
    10141 cccgatataa ccgtcactgc gcttcaaaat caactcaggc ttgccttgga ttttcagagc
    10201 cgcattgata cccgcgataa tcccttggcc agcagcttct tcataacctg atgttccatt
    10261 tgtctgacca gcagtgaaga gacctgagat tttcttggtt tccaaagtcg cacgcaactg
    10321 atgaggcaag accatatcat actcaatagc ataacctgtc cgcatcatct ctgcattttc
    10381 caaacctttg atggaatgaa ccaagtcacg ctggacatcc tcaggcagac tggttgaaag
    10441 tccttgaaca tagacttcct cagtattgcg cccttctggc tcaaggaaga gttggtgacg
    10501 ttccttgtcc gcaaagcgca caatcttgtc ttcaatcgac ggacagtaac gaggccccac
    10561 tcccttgacc acacctgtaa acataggcgc acggtggagg ttgttttgga taatctcatg
    10621 actggtacca ttggtgtagg tcaaccagca tggtacttgg tccttgacat aatcctcatc
    10681 acgtgaagtg tatgagaagt gattaggtgc ttcatctcct ggttggattt ctgtcacgtc
    10741 gtagttgata gaagaggcct tgacacgtgg aggggttcct gtcttgaaac gaccgatttc
    10801 gagacccagt tccttgagat tgtcagctag gttaatagaa gccaagctgt ggttaggacc
    10861 tgatgagtac ttgaggtctc cgatgataat ttccccacgg agagcagtcc ctgtcgtcac
    10921 aataacagcc ttagcagcat attcttgatg ggtggctgta cgcacaccga caaccttacc
    10981 atcttccacc aaaatctcat caatcatggt ttgacgaagg gtcagatttt cttgattttc
    11041 aactgtcttg cgcatttcct tagagtaaag ttccttgtca gcctgcgcac gaagagcacg
    11101 aacagctggc cccttccctg tgttgagcat cttcatctgg atgtaagtct tgtcaatagt
    11161 cttggccatc tcgccaccga gggcatcgac ttcacgcacg acaatcccct tggcagaacc
    11221 accgatagag ggattacaag gcatgaaagc cagcatttca atattgatgg tcgcaagcag
    11281 gaccttacag cccatacggc tagcggccaa ggaagcctca accccagcgt gtcccgcacc
    11341 aattacaata atatcgtatt cttcagtaaa atgataagtc atgtttctct cctattcctc
    11401 aagatgaatg tgtcttagtt ggccttccca atctggtagg gctgttttta aaaaggctgg
    11461 aactagctgg atatcctcaa gcttatccaa gtcaatccac tcacagggct gccttttctc
    11521 atcttcctgc atggtcaacg gggcatcttc aagcaaatcc accagataat gaaactcgat
    11581 attgtgatag gaaacgccgt ccacttcaaa acgattttca accacaaaag ctagctgccc
    11641 agcttgagct ttaacaccca gttcttcctt cacttcacgg actaccgcgt cttccgtttt
    11701 ttcgttaact tgaatcgcac cgccgataat gtaatacttg cccttgtctt tggtgactag
    11761 aagcttgtga ttttggacaa tcaaggctgt cgcccgaaca ccaaaaaccg tattgtctac
    11821 ttttgtccga aagtcttgtt gagtcattct tgtcctttcc cttaaacgac acaaaaacag
    11881 tcaaaactcc aaagaagtgc aggacaaaaa agcctgcaac atccatgagc tttgaccatc
    11941 atttctattg ctgttattat tgtagcaaat tgagaaaatt tgtcaatcta aatgtactga
    12001 caaacttgtc catcgcggta agcattgtca atcaaaccgc cacctagaca ctcttcgcca
    12061 tcgtaaaaga caactgcctg tcctggtgta atcgcgcgtt gtggttccgc aaagataact
    12121 tctgccttgt ctcctttgac atggacggtc accttagagt caggctgacg gtaacggaat
    12181 ttagccgtac attctagcgt aaactcttct ggcatttcac gagtaaagtg gacttggcta
    12241 gcctctaggc tggttgacat gagcgaatca tggtagaaac cttggcctac atagagaata
    12301 ttcttgctta gatcttttcc gacaacgaac caaggggcat tgtcaccacc gtgttgccca
    12361 ccgataccga gtccgccacg ctgaccgatt gtatagtaca taagaccagc atgctcgccc
    12421 atatcacgac catccacagt catcatacga ccaggctgag ctggcaggta gttgctgaga
    12481 aagtttttaa agttcttttc tccgataaag caaatccctg tcgagtcttt cttcttagca
    12541 gtcgaaagac ctgcttcttc tgctagtttt cgaacttcag gctttttcaa atgtcctagt
    12601 gggaacatgg ttttttgaag ttgttcttgc gaaagttggc tgaggaaata ggtctggtcc
    12661 ttgccattgt ccacgccacg aagcatgtga acagtgccat cctcatcacg cgccactcga
    12721 gcataatgcc cagtcgctac atagtctgcc cccaaggtta tggcatagtc caaaaaggcc
    12781 ttgaacttga tttccttgtt gcacataacg tccggatttg gcgtgcgccc tgcacggtat
    12841 tccgctagga aatactcaaa aacgcggtcc cagtactctt tttcaaaatt gacagagtag
    12901 tagggaatgc caatctggtc tgccaccgca accacatcct tgtaatcttc ggtcgccgta
    12961 cagacgccgt tttcatctgt gtcatcccag ttcttcatga agataccgat cacatcgtag
    13021 ccctgctcct tgagcaaaag agccgtcacc gacgaatcaa caccaccact catccccacg
    13081 acaacacgtg ttttagagtt atcactcatg gtaagtctcc catctattcg tttattcacg
    13141 attgaaggtc gtgtgtgctt cacgattgaa ggtcgcttga gcagtattca ttataacacg
    13201 cttggttaga gaagacaagg aagagcttaa aaattgtttt ttaaaactta tagtcaatat
    13261 acagattatg tgaatgatgt gagtatacct tcttcttatc ttcattcaaa taactataat
    13321 aaataaaaca acccattttc tctaatctat ttttcaagtt agagaaaagg agtcgttttt
    13381 ttaatgacat ttcctgaaat cataagatag gtacctaaag aatacgaaca taaatctatt
    13441 caatcgaacc ttatctttgt ttcaaaatta aaatgtcaaa tgttcttaac atgatttaat
    13501 ttaatcggct taaacccatt caccgttttc attgacagta tatccgtcta cagttgtgtt
    13561 gactgcaagg gcacctaagc cattgacata gtaccattta tctgatactt tgaaccattg
    13621 gtttgctttc atagcacctg atgcttcaag atagtaccag gtatctccat ctttcaccca
    13681 acctgttgcc attgaaccgt tagcgttgag gtagtaccat gaaccgttga ctttagccca
    13741 acctgttgcc atagcgccgt tagcgtttag atagtaccat gaaccattgt attggagcca
    13801 acctgtcgcc atagcgccat tgctgttgag gtagtaccat gagccattgt attctagcca
    13861 acctgtcgcc atagcaccat tagcgttgag gtagtaccat gaaccattgt attctagcca
    13921 acctgtcgcc atagcaccat tagtattgag gtagtaccat gaatcattgt attggagcca
    13981 tcctgtcgcc atagcgccat tgctgttgag gtaataccat aagccgttga ctttagccca
    14041 acctgttgcc atagcaccat tagcgttgag gtagtaccat gagccattat tttgtagcca
    14101 gcctgttgcc attgaaccat ccgtattgta gaagtaccac ataccatttt cttgtttcca
    14161 gcctgttttt ggagtttctg gtttaggagc tggagctggt ttaggagccg gagctggttt
    14221 aggagccgga gctggtttag gagctggagc tggggcttc
//
LOCUS       DBEJKC010000049        14060 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.049, whole genome shotgun sequence.
ACCESSION   DBEJKC010000049 DBEJKC010000000
VERSION     DBEJKC010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14060
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.049"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..331
                     /locus_tag="ACL3G6_001589"
     CDS             <1..331
                     /locus_tag="ACL3G6_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0546088.1"
                     /translation="PMTYEEMMTSDFFEAWFQKFFLPTLTTPSVIIMDNVRFHRMGKN
                     VRFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEAL
                     LSCSCFN"
     gene            complement(533..2791)
                     /locus_tag="ACL3G6_001590"
     CDS             complement(533..2791)
                     /locus_tag="ACL3G6_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR0546089.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(3020..3250)
                     /locus_tag="ACL3G6_001591"
     CDS             complement(3020..3250)
                     /locus_tag="ACL3G6_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HGR0546090.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3440..4123
                     /locus_tag="ACL3G6_001592"
     CDS             3440..4123
                     /locus_tag="ACL3G6_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0546091.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            4123..4857
                     /locus_tag="ACL3G6_001593"
     CDS             4123..4857
                     /locus_tag="ACL3G6_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0546092.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            5011..5868
                     /locus_tag="ACL3G6_001594"
     CDS             5011..5868
                     /locus_tag="ACL3G6_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HGR0546093.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETGLVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAMDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            6010..6882
                     /locus_tag="ACL3G6_001595"
     CDS             6010..6882
                     /locus_tag="ACL3G6_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HGR0546094.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            7164..7847
                     /gene="rpiA"
                     /locus_tag="ACL3G6_001596"
     CDS             7164..7847
                     /gene="rpiA"
                     /locus_tag="ACL3G6_001596"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HGR0546095.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7861..9072
                     /locus_tag="ACL3G6_001597"
     CDS             7861..9072
                     /locus_tag="ACL3G6_001597"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019318858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HGR0546096.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            9074..9616
                     /locus_tag="ACL3G6_001598"
     CDS             9074..9616
                     /locus_tag="ACL3G6_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HGR0546097.1"
                     /translation="MTRYSLLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9632..10441
                     /locus_tag="ACL3G6_001599"
     CDS             9632..10441
                     /locus_tag="ACL3G6_001599"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGR0546098.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGGFKGLLKAILAEL"
     gene            10917..11312
                     /locus_tag="ACL3G6_001600"
     CDS             10917..11312
                     /locus_tag="ACL3G6_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase family protein"
                     /protein_id="HGR0546099.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            11322..11897
                     /locus_tag="ACL3G6_001601"
     CDS             11322..11897
                     /locus_tag="ACL3G6_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HGR0546100.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            11922..12433
                     /locus_tag="ACL3G6_001602"
                     /pseudo
     CDS             11922..12433
                     /locus_tag="ACL3G6_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-activated cytolysin C-terminal
                     domain-containing protein"
     gene            13091..13579
                     /locus_tag="ACL3G6_001603"
                     /pseudo
     CDS             13091..13579
                     /locus_tag="ACL3G6_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DeoD-type purine-nucleoside phosphorylase"
     gene            13583..13810
                     /locus_tag="ACL3G6_001604"
                     /pseudo
     CDS             13583..13810
                     /locus_tag="ACL3G6_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684207.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
     gene            complement(13833..>14060)
                     /locus_tag="ACL3G6_001605"
     CDS             complement(13833..>14060)
                     /locus_tag="ACL3G6_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGR0546101.1"
                     /translation="NYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDS
                     LVNPDEDTTAEERQNTFTDMMKVGLETLIAE"
BASE COUNT         4165 a         2582 c         3156 g         4157 t
ORIGIN      
        1 tccaatgact tacgaagaga tgatgacgag cgactttttt gaagcttggt ttcagaagtt
       61 tttcttacca acattaacca caccatcggt tattattatg gataatgtaa gattccatag
      121 aatggggaag aatgtaagat tccatagaat ggggaagcta gaacttttat gcgaagagtt
      181 tgggcataaa cttttacctc ttcctcccta ctcgcctgag tacaatccta ttgagaaaac
      241 atgggctcat atcaaaaagc acctcaaaaa ggtattacca agttgcaata ccttttacga
      301 ggctcttttg tcctgttctt gtttcaattg actatagcag attgaaatga gaacaaatcg
      361 attgggaaag taaaattaat ttctataaat gttttagcaa ttgtttcgta ctatttcaga
      421 ttcagtctac tatatatcat aatggacaaa gggcaagctg tcaagaaatt acagttattt
      481 tagtaaaaaa agaagcagaa aaatttcatt ttctactcct tttctatagg atttattttt
      541 ctttttcaga acttttaact tcagcttttt tggcagattt aatctgaatg tttcccttgc
      601 tagtcataac tgctttgaga tctttttcgc ttggattttc aaggtagtag tcagtgattg
      661 tgtcctcaat atagtcttga atagtccgac gaagtgggcg tgctcccatt tttggatcat
      721 aacctaggtc aaccaacttt tccttgacct tatcagttac atccaaacga atgttgttgc
      781 tagagaggcg cttgttaaca tctgctagca tgagctcgac aatctgaagg aggttatcct
      841 tgctgagagc cttaaattcg ataatgccat caaaacggtt cataaactct gggctaaaga
      901 agttaccgag ttcaccgagg acagaattgg tacgtccttc tctagcagca ccaaatccaa
      961 cgctagcttc ggtctttcct gtacctgcat ttgaggtcat gataatgatg gcatccttga
     1021 agctaacggt gcgtccttgc ccgtctgtca aacgaccatc gtccaagact tgaagaaaca
     1081 tgtgcataac atctgggtga gctttttcca cttcatcgag aaggatgaga gaatatggat
     1141 tgtggcgaac tttttcagtt aattgaccag cctcatcata gccaacataa cctggagggg
     1201 cgccgaccaa cttagccaca ctatgttttt ccatgtattc actcatatca aagcgaatca
     1261 tactatcagc agaaccaaaa agttcgatag ccagttgttt ggaaagttct gtcttaccga
     1321 caccagttgg cccaacgaag aggaagcttc cgattgggcg gttaggggta ccaagtccga
     1381 cacgattacg gcgaatagcc ttggcaatct tatcgactgc atcatcttgg ccaataacat
     1441 gagacttgag atcttcggct agatggatga gttgagattg ttctttctct ttcaaatcac
     1501 caacagggat attggttttc tgctcgataa tgtgctcaat agttttctcg ctgatgatag
     1561 gagtatcctg gtctgtgatc tttttctttt gcatttcctt atacttggca atctggtcgc
     1621 ggaagtaggc cgccttctca aaatcttctt ctcgtgtagc ttgagacttg agattttcag
     1681 cctcaatcaa gcgctgatca attactttag gatccacaaa attcaaggtc aagttcatct
     1741 tagaaccagc ttcatctagg aggtcaatgg ccttgtcagg caagaagcga tcttggatgt
     1801 agcgattgga aagagttgca gctgcttcaa tcgcagcatc ggtatattga acgtggtggt
     1861 aatcttcgta tttcttttga atccctttga gaatagtgat tgtttcgtcc accgttggtt
     1921 catcgacttt aacaggctgc atacgacgct cgagggcagc atccttttca atgatacggt
     1981 attcattgag ggtagtagca ccgactagtt gcagttctcc acgagcaagg gctggcttga
     2041 ggatatttcc tgcgtccata ttaccatcac tcgcagaacc agcaccaaca atttcatgga
     2101 tttcatcgat aaagaggatg atgtcttcac gtttgcgaat ttcttccatg agtttttgca
     2161 tgcgttcttc aaattgtcct cgaatccccg ttccttgaac taagctaacc acatccagac
     2221 ggatgacttg tttaccttgg agtttatgtg gcacatcgcc atcgacaatt ttctgagcta
     2281 gaccttcgac aacggccgtt tttccgacac caggttcacc gataaggaca ggattattct
     2341 tggttctacg attgagaatc tcgatgacac ggataatctc atcgtcgcgc ccaataacgg
     2401 ggtcaatgtc tccacgacgg gcaatttcag ttacattaat accaaattct tccagcaggc
     2461 ctttttcttg gctaggtggc ggagtttgag cagatccacg attttgggaa ccataaccgc
     2521 cgtttccacc gtaacctcca cctgattggg ttgggggaat aggaggagta ttgctagaag
     2581 gtctgaaatt gtttagatca ttgaagaaat caccaaaggg atcgaagtca cgattgttca
     2641 gatccgtcat acctttgaag aggctattgt taggatctgt tttgataatc ttatagcagt
     2701 tttgacagag gtcaatttgt ttttgttttc cattgagatt ggtgtaaaga tgaattgttg
     2761 agtcgttaat tttacagttt tgacaaagca tacatctacc tcatttcttt ctttagcctg
     2821 acttgtttaa aggtcaaaaa tagtcaaatt ctatactctc attataacag gattggggtg
     2881 taaagcaagt aaaaagattg aagctttgag aagttgttac aatgaaaatt tttgtgaatt
     2941 tggactataa aaaaatccta tttgtgagac aaaaaggatt ttacttagac atgcagggac
     3001 aatcccagct tgttttagat tagtagagaa gttcgtaaat ttccattgcg attaagtcaa
     3061 tgctatcaaa cgtatacgtt tcgcgatctt ctacgtcacg aagggtaaag attgggccgt
     3121 tttcttcgtc gtggctgtac gcaacttctg caacaacaac tccttcgcgt tcaaaattac
     3181 gttttaaatt tccgccatcg tttgccattg cttcaaggcg gttgatgatt ctaaccaaat
     3241 gtgattccat tttgattctc cttcatttct tatcgttact attttaccat aaaggaggcc
     3301 aacttgacta gaaaaaacta agatttctca ctaattctgc tagtttaaag atttttaaat
     3361 aaattggata aaagatttaa attttaattc aaaacatgtt ataatcatac agtattctat
     3421 tttagaaagc agtgtgacta tgaatttttc ttttttacct aagtatttac cttattttaa
     3481 ctatggggct gttgtgacga ttcttatttc tatctgtgtt atctttttgg gaactatttt
     3541 gggtgttgtc ttggcttttg ggcaacgttc aaagtttaaa ccgcttgttt ggttggccaa
     3601 cttgtacgtt tggattttcc gtgggacacc gatgatggtt caaattatga ttgcctttgc
     3661 tcttatgcat atcaatgctc cgactattca gattggaatt ttaggtgttg atttttcgcg
     3721 tctgattcca gggattttga ttatctctat gaatagtggt gcttatgttt cggagactgt
     3781 tcgtgccgga atcaatgcgg ttccaaaagg tcagctagag gcggcttatt cgctagggat
     3841 tcgtcctaaa aatgcgatgc gttatgtgat tttgccacaa gcagtcaaaa atatcttgcc
     3901 agcattgggg aacgaattta tcaccattat caaggacagc tccctcttat cagctattgg
     3961 ggtcatggag ttgtggaatg gggctacaac agtttctaca acaacctatc tacctttaac
     4021 accactttta tttgcagcat tttactactt gattatgacc tctattctga cagtagcctt
     4081 gaaagctttt gaaaaacata tgggacaagg agataagaaa taatgacaga aaccttgata
     4141 aaaattgaaa atttacataa atcttttgga aagaatgaag tattgaaggg catcaacctc
     4201 gagattaaaa gaggagaagt tgtcgttatc atcggtcctt cagggagtgg gaaatctacc
     4261 ttgcttcgct ctatgaattt gttggaggaa gcaaccaagg ggaagcttat ctttgaggga
     4321 gtcgatatta cggacaagaa gaatgacctg tttgccatgc gtgagaagat gggcatggtt
     4381 ttccaacaat ttaacctctt tcctaatatg actgtgatgg aaaatattac cttgtcacct
     4441 atcaagacta aaggtgaaag cagggaagtt gctgagaaga gagcccaaga gcttttggaa
     4501 aaagttggtt tgccagataa ggcagacgct tatccacaga gtctgtcggg tgggcaacaa
     4561 caacggattg ccatcgcgcg tgggttggct atggaaccag atgttttgct ctttgacgaa
     4621 ccaacttcag ccttggatcc tgaaatggta ggtgaggtat tggctgttat gcaagacctt
     4681 gccaagtcag ggatgactat ggttatcgta acacatgaga tgggatttgc ccgtgaggtg
     4741 gcagatcgtg ttatctttat ggcagacggt gtggttgttg aagatgggac acctgagcag
     4801 atttttgaac aaacccaaga acaacggact aaagatttct tgagtaaggt tttataatct
     4861 attttaaaat ttcaagacaa gattagtgaa aagttcaacc agagcttttt cttatagttt
     4921 gaaactatag gataacctag gaaagaagtg ttagagggca ctagcagttt ttggtataat
     4981 ggaagatatt tgaaagaaaa gagaagtgat atgacacaga ttattgatgg gaaagcttta
     5041 gcggccaaat tgcaggggca gttggctgaa aagactgcaa aattaaagga agaaacaggt
     5101 ctagtgcctg gtttggtagt gattttggtt ggggataatc cagccagcca agtctacgtt
     5161 cgcaacaagg agaggtcagc tcttgcggct ggttcccgta gcgaagtagt gcgagttcca
     5221 gagaccatta ctcaagagga attgttagac ctgattgcta aatataatca ggatccagct
     5281 tggcatggga ttttggtcca gttgccatta ccaaaacata tcgatgaaga ggcggtttta
     5341 ttagccatgg atccagaaaa ggatgtggat ggtttccatc ccctaaacat gggacgtctt
     5401 tggtctggac atccagtcat gattccctcg acacctgcag gaattatgga aatgtttcat
     5461 gaatatggga ttgacttgga aggtaaaaat gcggtcgtca tcggtcgttc aaatatcgtt
     5521 ggaaaaccta tggctcagct tcttttggct aaaaatgcga cagtaacctt ggcccactca
     5581 cgaactcata atcttgccaa ggtggctgct aaagcagata ttcttgtagt cgcaatcggc
     5641 cgcgccaagt ttgtgactgc tgactttgtc aaaccaggtg cggttgtcat tgacgttggg
     5701 atgaatcgag atgaaaatgg gaagctctgt ggagatgttg attatgaggc agttgcacca
     5761 cttgctagcc atatcacgcc agtccctgga ggtgtcggtc ctatgaccat taccatgctg
     5821 atggagcaaa cttatcaagc agcacttcgg acattggata gaaaataaga gaaacattcg
     5881 attaatagag tgtattttct atagctatat ctaaaatggc agaaatgaat attaaatttt
     5941 agatataaga ttacaaaagg aggtctgcgt ctccttttta ttgtataata aaagtgagag
     6001 gaaaaaagga tgaaagtgat taatcaaacc ttattagaaa aagttattat tgaacgttct
     6061 cgttcaagtc ataaaggaga ttatggtcgt ctgctgctgc ttggtggtac ttatccttat
     6121 ggaggtgcca tcatcatggc tgctttagca gctgtaaaaa gcggtgcagg attggtgacc
     6181 gttggaacgg acagggaaaa tatcccggct ctgcacagcc atttacctga gcctatggcc
     6241 ttttctcttc aagaccagca attgttaaaa gagcaattgg agaaggcaga agttgtcttg
     6301 ctggggcctg gtttacgaga cgatgcttct ggagaaaatc tagtaaaaca ggtctttgtt
     6361 aatttaagcc aaaatcagat tttgattgta gacggaggtg ccttgaccat tcttgctagg
     6421 acaagtttgt catttccctc aagccagctt atcctaactc ctcaccaaaa agaatgggaa
     6481 aaattatctg gaattacgat tgaaaagcaa aaggaagatg caacggctag tgttctgact
     6541 tccttccctc aaggaacaat tttggtggag aaaggcccag ctactcgtat ttgggaagtt
     6601 ggccaatctg attattacca gttacaggtt ggtggtcctt atcaggcgac tgggggaatg
     6661 ggagatactc tggctgggat gatcgcagga tttgtaggcc aattccgaca agccagtctc
     6721 tacgagcgtg tggcagtagc gacccatctt cattcagcca tagcccaaga actatctcaa
     6781 gaaaattatg tggtcttacc gacggaaatc agcaggtatc ttcccaaaat aatgaaaatt
     6841 atttgtcaac aagagagggt aagtaaagat aaacttgttt aaaatagaca gataaatcta
     6901 cttccttctc ttaatttatg attcttgaaa tgcgcctgct ttaaggctaa actagacgta
     6961 tcaaagttaa gattttgttt ttgtaactgg aaagagatga acaaatcaaa tacataaaag
     7021 ataaactcat ttttattcgt ttggtaaaaa taaaatgcat atttttaaag aaagattgat
     7081 gaaaaatgta gatttgatgt ttttacttga ataaaaagcg gtttcatagt aaaataagaa
     7141 ctgagaatga tggaggtaaa tcggtggaaa atctgaagaa aatggcaggt atcaaggctg
     7201 ctgagttcgt gagcgatgga atggtcgttg gacttggaac aggctcgact gcctattatt
     7261 ttgtcgaaga aatcggtcgt cgtatcaagg aagaaggatt gcagattaca gctgtaacaa
     7321 cttctagtgt gaccactaaa caggcagaag gccttaatat cccgctcaag tctattgacc
     7381 aagtagactt tgtcgatgtg acggttgatg gcgcggatga agtggatagt cagtttaatg
     7441 gaatcaaagg cggtggtggt gcccttctca tggaaaaggt ggtcgcaaca ccatcaaaag
     7501 aatacatttg ggtggtggat gaaagcaagc tggtcgaaaa actaggtgct tttaaattgc
     7561 cagtagaagt ggttcagtat ggtgcagagc aggtctttcg tcattttgaa cgagctggct
     7621 acaaaccaag tttccgtgaa aaagacggcc aacgttttgt gacggatatg cagaatttta
     7681 tcattgacct cgccttggat gtcattgaaa atccaattgc ttttggacaa gaattggacc
     7741 atgtcgttgg tgttgtggag catggtttat tcaaccaaat ggtggataag gtaatcgttg
     7801 ctggacgaga tggagttcag atttcaactt caaaaaaagg aaaatagaag ggggcataag
     7861 atgtctaaat ttaatcgtat tcatttggtg gtactggatt ctgtaggaat cggtgcagca
     7921 ccagatgcta ataactttgt caatgcaggg gttccagatg gagcttctga cacactggga
     7981 cacatttcaa aaacagttgg tttgaatgtc ccaaacatgg ctaaaatagg tcttggaaat
     8041 attcctcgtg aaactcctct taagactgta gcagctgaaa gcaatccaac tggatatgca
     8101 acaaaattag aggaagtatc tcttggtaag gatactatga ctggacactg ggaaatcatg
     8161 ggactcaaca ttactgagcc tttcgatact ttctggaacg gattcccaga agaaatcctg
     8221 acaaaaatcg aagaattctc aggacgcaag gttattcgtg aagccaacaa accttattca
     8281 ggaacggctg ttatcgatga ttttggacca cgtcagatgg aaactggaga gttgattatc
     8341 tatacttcag ctgaccctgt tttgcagatt gctgcccacg aagacattat tcctttggat
     8401 gaattgtacc gtatctgtga atacgctcgt tcgattaccc ttgagcgtcc tgcccttctt
     8461 ggtcgcatca ttgctcgccc ttatgtaggt gaaccaggta acttcactcg tacggcaaac
     8521 cgtcgtgact tggctgtatc tccattttcc ccaactgttt tggataaatt gaatgaggct
     8581 ggtatcgata cttatgctgt gggtaaaatc aacgatatct ttaacggtgc tggtatcaac
     8641 catgacatgg gtcacaacaa gtcaaatagt catggaattg atacactatt gaagactatg
     8701 ggacttgctg agtttgaaaa aggattctca ttcacaaacc tagttgactt tgatgccctt
     8761 tacggccatc gtcgtaatgc tcacggttac cgtgattgct tgcatgagtt tgatgaacgc
     8821 ttacctgaaa ttatcgcagc tatgagagag aatgaccttc tcttgattac tgcggaccat
     8881 ggaaatgacc caacgtatgc aggaacggat cacactcggg aatatattcc attgttggcc
     8941 tatagccctg cctttaaagg aaatggtctc attccagtag gacattttgc agatatttca
     9001 gcgactgttg ccgataactt tggtgtggaa actgctatga ttggggaaag tttcttagat
     9061 aaattggtat aagatgacgc gctattcttt gctggtgaga ggtatcaatg ttggtggtaa
     9121 gaataaggtc gtcatggcgg agcttcgtca agaattgaca aacttgggac tggaaaaggt
     9181 tgagagctac atcaacagtg gcaatatttt ctttacttcg atagattcca aagcccaatt
     9241 ggttgaaaag ctagagactt tctttgcagt ccattatcca tttattcaga gcttttcttt
     9301 actgagccta gaggactttg aggcggaact tgaaaatcta ccagcttggt ggagcagaga
     9361 cttggcacga aaagattttc tcttttacac tgagggtttg gatgtggacc aagtcatcgc
     9421 gacagttgaa agtttagagc tgaaagatga agtgctttat tttggaaaac ttgggatttt
     9481 ctgggggaaa ttttctgaag aatcctattc taagactgcc tatcataagt acttgctgaa
     9541 ggtgcctttc taccgccaca ttactattcg taatgctaaa acctttgaca aaattggtca
     9601 aatgctaaaa aaataataaa ggagacacac aatgacattt ttaaacaaaa tccatgaaac
     9661 tgctactttc ctgaaagaaa agggaattgc agcccctgag ttcggtctaa tccttggatc
     9721 aggacttgga gaattggcag aagaaatcga aaatccagtt gtagtagact atgctgagat
     9781 tccaaactgg ggccgttcaa cagtagtcgg tcatgctggt aaattggtat atggtgaact
     9841 ggcaggtcgc aaggtcttgg ctcttcaagg gcgtttccat ttctatgaag ggaatcctct
     9901 ggaagtggtg actttcccag ttcgtgtgat gaaagttctt ggatgtgaag gtgttattgt
     9961 aaccaatgca gctggcggta tcggatttgg tcctggtacc ttgatggcta tctcagacca
    10021 tatcaacatg acggggcaaa atccattgat gggtgaaaac ttggatgact ttggcccacg
    10081 tttcccagat atgtctaggg cttacacacc agaataccgt gccactgccc atgaagtggc
    10141 taaaaaactt aatatcaagc ttgatgaagg tgtctatatc ggagttactg gtccgactta
    10201 tgaaacacca gcagaaattc gttcctataa gacactggga gcagatgcag ttggtatgtc
    10261 tacggttcct gaagttatcg tggcagccca ctctggcttg aaagttctgg gaatttcatg
    10321 tatcactaac tttgcggccg gtttccaaga agaactcaat cacgaagaag ttgtagaagt
    10381 gactgaacgt gttaaaggtg gtttcaaagg cttgcttaaa gcgattcttg ctgaattgta
    10441 agaaaaaaga tttaaaaggg ggagtgcctc tgtcttttca ggattgactg cctatccgta
    10501 ttaaagaaga aacagaggaa tactatgagc ttcttcctgc tcttataact gaaagaagcg
    10561 gaagaatagg tatgtctgat ctgatagcca gcattgtgaa agacaagatt ctaggatact
    10621 agcattagct tcctagccaa gcagactagt atgataagga gagatgagaa tgaattgact
    10681 ttctgaattt ctcagtctta tcatatatag cacaatgaga tttcgcttga gtctgcttgt
    10741 aaataaacga aaagaaagat aagaaataat gaaaattggt caacgaatta tgcgctttgg
    10801 cataaaaaat taagtatcgg agttgtatct gttgtagtcg gctttgattt ctagctccag
    10861 ctggaatttc agccaatgaa gtaaagcaag atgtaacatc tgaagtggta ataggtgtgc
    10921 tagattctaa ggaggaattg aaagagtcag aaaatgatgc tccaaaacta gaaactcctc
    10981 ttagagagga gccaagacta gctcctcaaa cgcttccgga agcaagtgaa gttcttgaaa
    11041 acaaaaggga agagtcaaaa gtagagataa cagagccagc tcaagcggat gatatccgca
    11101 aggttgttgg ggaattagcc aaggatataa gtattactaa gttgtatatg acaggtcatt
    11161 ctcttggagg ctacctagct cagattgcag cggttgaaga ttaccaaaaa tatcctgatt
    11221 tttataacca tgtattgagg aaagtgacaa ctttcagtgc tcctaaagtg attacttcca
    11281 gaactgtttg ggatgctaag aatggtttct gagatgttgg tttggaaagt cgtaaattag
    11341 ctgttagtgg aaaaattaag cattatgtgg ttgataatga caatgttgtg actcccttga
    11401 ttcataataa tcgtgatatt gttacattta caggtaattc acgctttaaa caccgttctc
    11461 gtggctattt tgaaagtcca atgaatgata ttcctaactt taatattggt aaacaagcta
    11521 ccttggataa acatggttat cgtgatccga aattggataa agtgcgattc tttaagaaac
    11581 aggctctacc tcaatcttct agtcaaccaa gcgctgaacc aatggaaaat attgccttag
    11641 gaaaacaggt tactcaaagt tcgacagctt tcggaggaga tgctagaaga gctgtggatg
    11701 gcaaagtcga tggtaactat ggtcacaatt ctgtcactca tacaaacttc caatctaagc
    11761 cttggtggca agtagatttg gctaaagaag aaaccattcg ccaaatcaat atttacaacc
    11821 gaacagacac tgcccaggat agattggcaa actttgatgt cattctttta gacagttctg
    11881 gtaaagaaat tgagtgaaaa cgtataatat ctcctaaaga tgtgtcagca caaattacga
    11941 ttaaccataa aaaacgcgct atgttcggat tgagctagaa ggctataatg ccctcagtct
    12001 tgcagaagtt gaagttttcc gctttatagc tacgaatgct gaaacggcga cacaagtttc
    12061 taagccagtt caaccaatca gtcagactcc tgtgaaagat aaaacattga caattcaaca
    12121 cagtggagct tacattgccc gctactccat aacttgggaa gaagttccag tagataaaga
    12181 tggaaaccaa gttgttcgta gtcattcttg ggaaggaaac ggttgcaacc agactgcagg
    12241 ttttgtcctc aacctcccaa tcaaagaaaa tatgagaaat ctgcgagtta agattgagaa
    12301 aaagacgggc ctactatgga atagatggca aacaatctat gaaaacagac caattttagc
    12361 tcaaccccac cgtaaaatta cccattgggg tacgacattg aattccaagg tgagtgacga
    12421 tgatgtcttg taatctgatg gtacaatgac agttagtttg tctagtttat aagaaagtac
    12481 tacctgagct tgaatagaac tcaggtagct ctctgtgaaa gaacaaaatt aatactcaat
    12541 gaaaatcaaa gagcaaacta ggaaactagc cgcaggttgc tcaaagcact gctttgaggt
    12601 tgtagataag actgacgaag tcagtcacat atataatcca aggcgacgtt gacgtggttt
    12661 gaagagattt tcgaagagta taaacagaaa ggtagagcgc gtgttctaat ttgaacacga
    12721 gtagaaaact tttctaaaaa caaaaacgaa aggatgggta aactgtattc gctgaactga
    12781 atacgggcga ctctcctcta aatcaaaatt aagaaagaaa ggaattgacc ccaccctaaa
    12841 agcagtggga aaaagatagt tggtctagcg agcatcgctc actgcgccca actcctattt
    12901 tcccttcgct ttttgacggg tttggtatct ttctcaatat aaaatataaa ataaagaaag
    12961 gtagagcgtg tgttttgatt tgaacacgag cggaaaactc ggaaaataga taatctgact
    13021 gaaaaatcag gatttctcgt cggcttccta attttcagtc gttttcttct cgctctttgt
    13081 atcataaatt atgtctatcc atattgctgc tcagcagggt gaaattgctg ataaaattct
    13141 tcttcctggg gatcctcttc gtgctaagtt tattgcggag aatttccttg gtgatgctgt
    13201 ttgttttaac gaagtgcgta acatgtttgg ttacactggt acttacaagg gtcaccgtgt
    13261 atctgtcatg ggaactggga tgggaatgcc atctatttcg atttatgcgc gtgagttaat
    13321 cgtagactac ggtgtgaaga aattgattcg tgtgggaact gcaggttctt tgaatgaaga
    13381 ggttcatgtt cgtgaattag ttttggcgca ggcggctgca accaactcaa acatcgttcg
    13441 taatgactgg ccacagtacg attttccaca aattgctagc tttgatttgc ttgataaagc
    13501 ctaccatatc gccaaagaac ttggtatgac tactcacgtt gggaacgttt tgtcatctga
    13561 tgtcttttac tcaaattact agcgttatct taaataccgt ggaaaagtca gagaaagtat
    13621 ggcggcagat tgccctgaac gctttgactg ggagtttatc agatggattc tttgggatgg
    13681 acgtagcaaa actcaaaaag aaaattacca aaaactttgc caagaatatt cacataaagt
    13741 cactattctt cgaaatcaga gagagctaga tcaatttctg gataagaaaa ggaagtccta
    13801 caattcataa agggcttcct ttttggctat aattattctg caatcaaggt ttccaaacca
    13861 accttcatca tatcagtgaa ggtattttga cgttcttctg cagttgtgtc ttcgtctgga
    13921 ttgaccaagc tatcagagat ggtcatgata gctagcgcat caacatggta ttgggcagca
    13981 agatagtaaa gagctgctgc ttccatttcc acagccttga ctccccattt accaagctcg
    14041 atattctttt caaagtaatt
//
LOCUS       DBEJKC010000050        14042 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.050, whole genome shotgun sequence.
ACCESSION   DBEJKC010000050 DBEJKC010000000
VERSION     DBEJKC010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14042
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.050"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(149..328)
                     /locus_tag="ACL3G6_001606"
     CDS             complement(149..328)
                     /locus_tag="ACL3G6_001606"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0546102.1"
                     /translation="MQKANTKLEKPINQPLSSHIFRHTLLSTLAEKNAIMVRVEHKNA
                     KTVNNIYTHVSKRME"
     gene            complement(504..719)
                     /locus_tag="ACL3G6_001607"
     CDS             complement(504..719)
                     /locus_tag="ACL3G6_001607"
                     /inference="COORDINATES: protein motif:HMM:NF012920.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S24 family peptidase"
                     /protein_id="HGR0546103.1"
                     /translation="MEPKIRNSDYLFIKNTPQIDYNTIGIFQVDGTNYVKKLRQGYLK
                     KTQSRILRHPPRRKQPYSYHRESCQAI"
     gene            1567..2439
                     /locus_tag="ACL3G6_001608"
     CDS             1567..2439
                     /locus_tag="ACL3G6_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HGR0546104.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2585..2929)
                     /locus_tag="ACL3G6_001609"
                     /pseudo
     CDS             complement(2585..2929)
                     /locus_tag="ACL3G6_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3072..3383
                     /locus_tag="ACL3G6_001610"
     CDS             3072..3383
                     /locus_tag="ACL3G6_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546105.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKKREELRQIITTIFEQKMNKHSI
                     K"
     gene            3387..4103
                     /locus_tag="ACL3G6_001611"
                     /pseudo
     CDS             3387..4103
                     /locus_tag="ACL3G6_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            complement(4233..5048)
                     /locus_tag="ACL3G6_001612"
     CDS             complement(4233..5048)
                     /locus_tag="ACL3G6_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HGR0546106.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(5045..5950)
                     /locus_tag="ACL3G6_001613"
     CDS             complement(5045..5950)
                     /locus_tag="ACL3G6_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HGR0546107.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            complement(5951..6082)
                     /locus_tag="ACL3G6_001614"
     CDS             complement(5951..6082)
                     /locus_tag="ACL3G6_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HGR0546108.1"
                     /translation="MAVKFTKRDDLDKMFEEFAKLPDLKQVTFPDDKEKKVKAEKKN"
     gene            complement(6196..6399)
                     /locus_tag="ACL3G6_001615"
     CDS             complement(6196..6399)
                     /locus_tag="ACL3G6_001615"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546109.1"
                     /translation="MKIKKQTRKLAAGCSKYCFEVVDKTDEVSSKHCFEVVDKTDEVS
                     SKHCFEVVDRTDEVSNRTTVRRS"
     gene            6452..8581
                     /locus_tag="ACL3G6_001616"
     CDS             6452..8581
                     /locus_tag="ACL3G6_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HGR0546110.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIADLEKEAEKFVCEGFATGKEALAGAVDI
                     LVEALSEDVTLRAMTYQEVLRHSKLTSQVKDESLDEKQVFQIYYNFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNINTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKQIDTEREKVNLSLLAPNETD"
     gene            8568..9017
                     /locus_tag="ACL3G6_001617"
     CDS             8568..9017
                     /locus_tag="ACL3G6_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HGR0546111.1"
                     /translation="MKLTDYVKQVSLEDFGRSFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTRRYRCGLCRGKLLLINQPED"
     gene            9076..9348
                     /locus_tag="ACL3G6_001618"
     CDS             9076..9348
                     /locus_tag="ACL3G6_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGR0546112.1"
                     /translation="MNSKFYKMRRNRMISGVLVGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(9702..9893)
                     /locus_tag="ACL3G6_001619"
     CDS             complement(9702..9893)
                     /locus_tag="ACL3G6_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546113.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            10321..11079
                     /locus_tag="ACL3G6_001620"
     CDS             10321..11079
                     /locus_tag="ACL3G6_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0546114.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            11081..13069
                     /locus_tag="ACL3G6_001621"
     CDS             11081..13069
                     /locus_tag="ACL3G6_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0546115.1"
                     /translation="MFRLTNKLAISNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKKLGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKRGRFLPLQTILGSISLGIGYYLAL
                     TVTDPLTALTIFFLAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLNQFPDSDIYNQFYGGMNVSISEEEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSVLFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQIINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(13111..13785)
                     /locus_tag="ACL3G6_001622"
     CDS             complement(13111..13785)
                     /locus_tag="ACL3G6_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HGR0546116.1"
                     /translation="MDSNFAGRLNILRAGVLDANNGIISIAGVVIGVASATTNIWIIF
                     LSGFAAILAGAFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQN
                     GECKTSAQLLTNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPML
                     SVTIFPSEYRIPATVLIVGVALLLTGYTSARLGKAPARTAMIRNLAIGLLTMGVTFLL
                     EQLFSI"
     gene            complement(13781..>14042)
                     /locus_tag="ACL3G6_001623"
     CDS             complement(13781..>14042)
                     /locus_tag="ACL3G6_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0546117.1"
                     /translation="DVFSEEHIYYAHPYASWERGTNENRNRLIRRWLPKGTKKMTPKE
                     VAFIEKWINNYPKKYLDYKSPREDFLMANLNLKFSVRNKSRN"
BASE COUNT         4300 a         2610 c         2876 g         4256 t
ORIGIN      
        1 tcattgagta tgaaataaga tatgcacaaa ttgattagaa agtcaaatga atttctacaa
       61 atgttttagc aatcgtaatg tacttgtcta gattcgatct gatatatttt cgatttaatg
      121 atatggtatt taaaacctcc aaagtagctt actccattct tttacttacg tgagtgtaga
      181 tgttatttac tgttttagcg tttttgtgtt ccactctaac cattatagca ttcttctcag
      241 ctagtgtact aaggagtgtg tgcctgaaaa tatgggaact aaggggctgg tttatcggtt
      301 tctctagttt agtatttgcc ttttgcaaag tgatcttaaa tgcctttctc taaatttaca
      361 tatcactatt gtttaacaaa atctaatcta tcttaggtca cttattcttt ttttgaaatg
      421 tagaatgaac tttttcaaag tttttcgaat cttttaaaat ctgtttgttt tatatcgcca
      481 ttctccccct tttttaattc tccctatata gcctgacaac tttcccgatg gtacgaatat
      541 ggttgctttc gtctaggtgg atgtcggagt attcgggatt gagttttttt gaggtagcct
      601 tggcggagtt tcttgacata gttagtgccg tctacttgga agatgccgat ggtattatag
      661 tcaatctgtg gggtattctt gataaatagg tagtcgctgt ttcttatctt tggctccatg
      721 gacttgctga cgacataagc gattgggtcg tagtcgtctg ggataatgga aactccataa
      781 ctaaatcgtc gtcctgcatc aagcggctac ctgcagagat aaactaccta acacgagagt
      841 aagtagtctg tctgtagtcg tccagtctga tgatttttac gatacttcgt ttttctgatc
      901 atacagttgc ctctcggcat aggtcagaac tttaccttgt ctgggtggtg cccgttggtc
      961 gtagatagat tggatatcgc taggagaatc cttttgaact ggaggaaaga gggcatcaat
     1021 caagctactg aatactttaa ctaagtcaaa tatagtattt ttcttagtag acctaaccct
     1081 tttttcataa tttctaatgg tgtttttact tatacctatc ttagtaccca attcttattg
     1141 agtccaacca ttactagtct atattgtttt atagttgatt gagtttggaa tagtacgctg
     1201 tagctgctaa aacatttcta ggaattaatt tgcctttcct aatagagttg ttcatatctt
     1261 atttcaatct actatatttt tcacctctaa caatcgcaat ctcttcttta tccatgaacg
     1321 aaaacgcttt ctatctttgt aagtaaagca tcacacgaaa tccacgaaaa tgaaaacctt
     1381 tgttgtgttt tcgtaaaaaa tttgttgaca gagcacgaaa cgcctactat aattaaatca
     1441 agtttaagga aataacaaaa aaacaaatcg gagggaaaga cgatgaacac attaaatgag
     1501 aaagtaatca atatctgtaa agcagtagtt aaagaaactt taatccaaga catttaggag
     1561 aaagaaatga agaaatcaag aaaattagcc acattaggaa tctgttcagc cttgttttta
     1621 ggcttggctg cttgtcaaca acaacatgct acttctgagg ggacgaatca aaggcaaagc
     1681 agttcagcga aagttccatg gaaagcttca tacaccaacc taaacaacca ggtaagtaca
     1741 gaagaggtca aatctctctt atcagctcac ttggatccaa atagtgttga tgcatttttt
     1801 aatctcgtta atgactataa taccattgtc ggctcaactg gcttatcagg agatttcact
     1861 tcctttactc acaccgaata cgatgttgag aaaatcagtc atctctggaa tcaaaagaag
     1921 ggcgatttcg ttgggaccaa ctgccgtatc aatagttatt gtcttttgaa aaattcagtc
     1981 accattccaa agcttgaaaa gaatgaccaa ttgcttttcc tagataacga tgcgattgat
     2041 aaaggaaagg tctttgattc acaagataag gaagagtttg atattctatt ttcgagagtt
     2101 ccaactgagg caactacaga tgtcaaggtt cacgctgaaa agatggaaac attcttctca
     2161 caatttcaat tcaatgaaaa agctcgaatg ctgtctgtag tcttgcacga caatctggat
     2221 ggcgagtatc tgtttgtagg tcacgttggg gtcttagtac ctgctgatga cggtttctta
     2281 tttgtagaga aattgacttt cgaagagccc taccaagcga ttaaatttgc tagtaaggaa
     2341 gattgctaca agtatttagg caccaagtat gcggattata caggcgaggg actggctaag
     2401 ccttttatca tggataatga taagtgggtt aaactttaat agtgttatga tatgacagta
     2461 atcttaggat ttttatttct atttttgatg agttggtggg ttatttcaat cgttaatagc
     2521 cagaaaccac gcaaaaatga aacatttatt ggctatatcc aaagatacga tattgatggg
     2581 aatggctatc aatcattacc gtgtcctcag aactgagagg agttcttgaa atcgtaaaac
     2641 tactttgaac aagagttact tcaacccatt ggctccgacg gattaagttg ctttcgtgaa
     2701 caccaaaatc agccgcaatt tcttcataag tgcggtattc tcgcacatat tgaagagtgg
     2761 ccataagaag gtcttctagg cttaatttag gttttcgtcc cccttttgtg tgtttaagtt
     2821 gataagcagt ttttaataca gctaacatct cttcaaaagt ggtgcgctga acaccaacaa
     2881 gacatttaaa tcgtgcatca gttagttgct tacttgcttc atcattcata gaactactat
     2941 accatatttt gtttcgcagg aagtctaatg ctaaaatctt atcagtgaga agatttctta
     3001 aagtttattc tttgtagttt catctgtatt agtacataat ttaacttaga gaaaatagga
     3061 ggactaatcg aatggaatta aaagatttta cagaaaaaga acaggaaatg attaagaaaa
     3121 ggcttacaat gtctaatatt agtgacaaag aaactactga gaagattctg gcgctagtac
     3181 cacaagactt gattaagcga atcccgtttt ttgtcagaaa acatgctaca acacgtacga
     3241 ttaaacgcat ttcaattgaa caccctgaac tctacgctgt agctcaaaca agtggtgaga
     3301 ttccagaaaa aaaacgcgaa gaattgcgtc agattatcac aactatcttt gaacaaaaga
     3361 tgaataagca tagtattaag tagagaatga aaaaatattt tattggcggt ttgggaagca
     3421 atgcctatca tagcaaggat tttctttaag aactagattc gcaggtctat tttctaaatc
     3481 catatgaaaa gcatcttcga gatgaaacag aattgaaatc atggtttaaa aatgagattg
     3541 tagaggaaga atctatctgt ctgataggtc attctattgg aggcgattta gctcgttatt
     3601 tcgcatcgga atttgaagaa gtaaagaaac tgattctttt ggatggtggc tatctagatt
     3661 tagataagat tttacctttg gatacagagt tagaggaaac taaaaattat atcaaatctc
     3721 aaattatttc ggacttagat gttcttactt ctaaagaaaa atctgaagca aagcattggt
     3781 cagaaaatat ggagaaagct gtaagacagt cctatcactg gaatgttgag tataatagat
     3841 atgagttggc tataaattat gaaaatatag aagcgatact ccgcctacgg agaaaaatac
     3901 aagcttttaa gagagaagtg ggagatacct tgtttattag tcctcgctat cctaatgaag
     3961 ctacatggag agaggaagcc ctaaaagaat tgccagacta ttttgatact atttttttag
     4021 aaaactttgg ccatgagctt tatactcaag cacctaaaga aatcgctagt ctaatgaatg
     4081 agtggctcgc ttattttcta tgagctactt gtattgctgg aaatggtata agatgaaaat
     4141 ctacaagtca ctaattttca tataacaaaa aaacgaacag gctctttttc tgttattcag
     4201 aagagaactt gttcgttttt atcttgattt tcttaaaaag ctctatatac atagggattt
     4261 tctggtttat cgactttggt aaagctgtcg atttccaagg ttggaaggtt ttgtttgagt
     4321 tctttatggt agtgattgac cagttttcct ttggctgtaa tccaggtgtt gttttcatac
     4381 tgccgggtat tgcccttggt cagcaatcca tagacaccag aatctgcgat acagtggata
     4441 atgccgaatc ggaacagaaa ttgactattg gcatgactgg ggtcgttata gacaaagcct
     4501 gtaaactgga ttgtcttgcc ctcaaattca tctggatagt cgtagatagc ctccatgact
     4561 tccatatagt tttcattagt gatctgaata ctatcttggg ataagtattt atccgccgcc
     4621 gttcgcattt ccttttcata ggctgatttt gaaaaataag aactagtatc tggtttcaaa
     4681 tattggcttg tagtcccttc acttgtctga atagctagat ccgttccttc cgataggggg
     4741 aaatgataac ctttagcaga aacggtctga gaatccaagc taacagttgg gaaagttaag
     4801 ccgatgacaa gtggaatagc cagaagagaa atactcgtca tcttggccaa tcggctgttc
     4861 agatgactgt gggttttgac ttgcttcatc cagatataca attgaacaat tgccaagata
     4921 aaggaaagca ccatggagat ataggccaga taggaatagt gcatgttgat gtactggttt
     4981 agtttgcccg acagatggag gtaaatagtc agttcaaaat agccagctaa aactaaaaat
     5041 cgaatcatag gatgactcca atcaagagag aataggctaa aacgaccaga gtcacaatcg
     5101 taatgaagtg actaataaat cgtgctttca agtaattttt catcatgaga atatttttga
     5161 tatccagcat tgggccaatg acgagaaagg ccagaactgg tgccaaaccg aaactcgaga
     5221 gtagagaagc acctataaag gcatccgcct cactacagag cgaaagaaga aaggctaaaa
     5281 gcatcaagag caggatagca aaaagaggag tcgcactgat agaggtcaga atccgagtcg
     5341 gaacgtagac ctgtattata gaagcaaaga ggcagccaaa taccaaataa cgccccgtat
     5401 caaaaaattc atcaatggcc tgcacaaaga cttgaaaaac tttttttgca gaactcaagt
     5461 aagaaaaatc atgctcatga caagccagac gattttcttt ctgaatcggt tcttgccaga
     5521 aaaatcctag aaaaattcct agtattacag ccacaagaat ggaacccaga gctcgtaata
     5581 gtgcgacatg gaaggagttg ccaaaggcag aataggtcgc aaaaagaaca atgggattga
     5641 taacaggtgc tgtcacaaga aaaggaacgg ccgtgtaact tggaaccttt ttttccagaa
     5701 aacgattgat gatggggacg attccacatt cacaagaagg gaaaagtata ccgacaaagg
     5761 tcccaaaaaa gattctcccc caacgatttc gagggagaaa atgataaacc ttgtcaggtg
     5821 tgatataaac ttcaatcagc cctgagacaa tgcttcctat cagaacgaag ggaagggctt
     5881 caatgataat ggagagaaaa atggctccag tttgaagtac actagatggg agttgttgaa
     5941 aagcagtcat ctagtttttc ttttctgctt tgactttttt ctctttgtca tcagggaaag
     6001 taacttgttt caaatcaggg agtttagcaa actcttcaaa catcttgtcc aagtcgtctc
     6061 gttttgtaaa tttgacagcc ataggtgtac ctcgattcta aattctacct ctattatact
     6121 attattttgc ggaaaaggga gttttttaat ttgttttcga tagttgatac acttcgaaaa
     6181 tctcttcaaa ccacgtcagc ttcgccttac cgtagtacgg ttactgactt cgtcagttct
     6241 atccacaacc tcaaaacagt gttttgagct gacttcgtca gtcttatcca caacctcaaa
     6301 acagtgtttt gagctgactt cgtcagtctt atccacaacc tcaaaacagt attttgagca
     6361 gcctgcggct agcttcctag tttgcttttt gattttcatt gagtatgaaa aggattggag
     6421 aaagccttcc agcttgtggt ataatagatt tatggataaa aaatatgaaa aaatctctca
     6481 ggatttggga gtgacgttaa agcaaattga taccgttcta agtttgacag ctgaaggggc
     6541 gactattccc tttatcgcgc gttatcgcaa ggacatgact ggtagtctgg atgaggtggc
     6601 gattaaggct attattgatt tggataaaag tctgacaaat ctcaatgacc gtaaggaagc
     6661 tgtcttagct aagattcaag aacaaggtaa gttgaccaag gaattggaag aagctatctt
     6721 agttgccgaa aaattagcag acgttgaaga actctatctt ccttataagg aaaagcgtcg
     6781 taccaaggca accattgccc gtgaagctgg actctttcct cttgctcgtt tgattttgca
     6841 gaatatagct gacttagaga aagaagctga aaagttcgtc tgtgaaggat ttgcgactgg
     6901 taaggaagct ttggctggtg cagttgatat cttggtcgaa gccttatcgg aagatgtgac
     6961 actgcgtgct atgacttatc aggaagtgct gagacactct aaactcactt ctcaagtcaa
     7021 ggatgaaagt cttgatgaaa aacaggtttt tcagatttat tataattttt cagagacagt
     7081 tggaactatg caaggctatc gtaccttggc tctcaatcgt ggggagaaac ttggtgtctt
     7141 gaagatcggt tttgaacatg cgacggaccg tattcttgcc ttctttgcta ctcgtttcaa
     7201 ggtgaaaaat gcttatattg atgaagttgt tcagcaatcc gttaagaaaa aggtcttgcc
     7261 tgctattgag cgtcgtattc ggacagaatt aactgagaaa gctgaagagg gagctatcca
     7321 acttttttct gacaatctgc gcaatctcct cttggttgct ccattgaaag ggcgcgtggt
     7381 tcttgggttt gacccagcct ttcgtacagg tgccaagcta gctgtcgtgg atgcaacagg
     7441 aaaaatgctg acaactcagg tcatctatcc tgttaaacca gcatcagctc gtcaaatcga
     7501 agaagccaag aaagatttag cagatttaat tggtcaatac ggtgtagaga ttattgccat
     7561 tggaaatgga acggccagtc gtgaaagtga agcttttgta gcggaagttc tgaaagattt
     7621 ccctgaagtc agctatgtta tcgttaatga aagtggtgct tctgtctatt ctgccagcga
     7681 acttgctcgt caggagtttc cagacttgac cgttgaaaaa cgctctgcca tttctatcgc
     7741 ccgtcgtttg caagatcctc ttgcggaatt ggtcaaaatc gatcctaagt caattggtgt
     7801 cggtcaatac caacacgatg tcagtcagaa gaaactatct gagagtctgg actttgtcgt
     7861 ggatacggtg gttaaccaag tcggtgtcaa tatcaatacg gccagtccag ctcttctttc
     7921 tcacgtggct ggactcaata aaaccatttc tgaaaatatt gtcaaatacc gtgaggagga
     7981 aggaaaaatc acttcacgct cccaaatcaa gaaagttcct cgtttggggg ctaaggcctt
     8041 tgaacaggca gctggtttcc ttcgtatccc tgaaagtagc aatatccttg ataatacagg
     8101 agttcaccca gaaaattacg ctgccgttaa ggaactcttc aaacgcttgg acattaagga
     8161 cctgaatgaa gaggcccaaa gcaaactcaa gtcgctttca gtcaaggaaa tggcgcaaga
     8221 gttagacctt ggtccagaaa ctcttaaaga tatcattgca gatcttctca aaccaggtcg
     8281 agatttccgt gattcctttg atgctccagt tctccgtcaa gatgtcctag atatcaagga
     8341 cttagtggtt ggacaaaagc tagaaggagt ggtgcgtaac gttgttgatt tcggtgcttt
     8401 tgttgatatc ggaattcatg aggacggtct catccatatt tcccatatga gtcgcaagtt
     8461 tatcaaacac cctagtcaag tggtggcagt tggagatttg gtgagcgttt gggttaagca
     8521 aattgatact gaacgtgaaa aagttaatct gtctctccta gctccaaatg aaactgactg
     8581 attacgtcaa gcaggtttca ctagaagact tcggcagatc ttttatccat catgtccagt
     8641 ggaataggcg tctacgttcg acaggtgggc gatttttccc caaagatggg catttggatt
     8701 ttaatcccaa ggtttatcag gaactggggt tggacgtttt taggaaaatt gtccgacatg
     8761 aactctgtca ttatcacctc tattttcaag ggaaaggcta tcaacataag gatcgagatt
     8821 ttaaggaact gttgaaagca gtggatggat tacggtttgt accatccttg cccaatagta
     8881 actccaagcc aatcaagctc tatcgttgcc aatcctgcca gcaaacttat cagcgtaagc
     8941 gaagaattga taccagacgc tatcgctgtg gactttgtcg aggtaaattg ctactaataa
     9001 atcagcctga ggactgatga aagccgagcc tacccgtgat atactatgtc taacttagca
     9061 gaaagaggaa atatcatgaa cagtaaattt tataaaatga gacgaaatcg catgatttca
     9121 ggagttttgg taggcctgtc agacaagtgg aactttgatg ttacccttgt acgttttctg
     9181 tttgccattt ttacagtcgc aaactttgga cttggggtga ttatctatat catcctagct
     9241 tctatcatgc caaccaagga agaaatcgaa gcagaaatgt acggaacagg cccacgtaaa
     9301 cgcaaagaag ctcaagccat tgacgataat gaaggctggt tttggtgagg ttttacaaaa
     9361 gatttggaat acgcaaaaag ctttaaatca atagtctaaa ctgcttgatt taaagctttt
     9421 ttacttttat actcaataaa aatcaaagtg caaactagga agccagccgc aggctgtaat
     9481 ttagtcggca atgtgaagtt aacatagttt gcactttgat ttttgaatag tattaataat
     9541 atttcgccag cttcatccac aaactatagt ggattggaac tagaatagta cacctctact
     9601 tctaaaatat tgttagaaat cgatttgact atcctgatcg atttgtcctg tttttatttc
     9661 attttattat aaaagcagta atttaaactc agttttttaa tctatttttg ctgctgagac
     9721 aatacatttt tggaaaaatg gtggatgctg ataacaactg ataaccagca aataacataa
     9781 gcagtgccgg taaattctgt accgataaag tgtgtgtgtt caactaagag ctgaccgatg
     9841 aatggagaga ggagatagag aagtccgatg agtatatgtt ctttgtgttt cattaaagcg
     9901 caccttcttt ccttataggt tgaacgactt gcaagtgtta aattgaatgg tatgttatct
     9961 aggtaagctt actcaaatga tagttcccgc ttcctccttt tcaaagtaag ccttttcaca
    10021 cttatgtttt acaactttaa aaataggaaa tcaaatcatt ttctaagtaa ttttgcttat
    10081 atttcaccca atcttacaaa aatgtaagat taaagtctct tttgtaaggt taggttatgg
    10141 caagcggtct ttttttgatg taaactagac tcataaagaa caaaggagta acatcatgaa
    10201 acaaatctta cataagaaaa ctagaaaacc aagtcacaaa gaaattgagc gcgttcagct
    10261 gggatgcact atgatgcaag ctacatttca tttgatggga tattaagaaa ggagattctc
    10321 atgacacttt tagatgtaaa acacgttcaa aaaatttata aaacacgttt tcagggcaac
    10381 caagtagaag ccctcaagga tattcacttt accgtcgaaa agggtgacta cgttgccatc
    10441 atgggtgagt ctggttctgg taaatcaact cttctcaata ttctagctat gctggataaa
    10501 ccaagtcgtg gtcaggttta cttgaatgga actgacaccg caaccattaa aaattcacag
    10561 gcctctagct tccgtcgtga aaagttgggc tttgtcttcc aagactttaa cttgctagat
    10621 actctatctg taaaggacaa tatcttgctt ccgcttgtct tgtcaagaag acctattaca
    10681 gagatgatga agaaattggt ggtgacagct gagaatctgg gtattaacca attgcaagag
    10741 aagtaccctt acgagatttc tggtggtcag aaacagcgtg tagcagtagc ccgcgccatc
    10801 atcacagaac ctgaaattct ccttgcggac gagccaacag gagcccttga ttccaagtca
    10861 tctgcagcct tacttgatgt ctttaatgaa atcaatgagc gtgggcaaac catcctcatg
    10921 gtaacccact caacagcagc tgctagcagg gccaagcgtg ttctctttat caaagacggc
    10981 attctttaca accaaatcta ccgtggagag aagacagagc gtcagatgtt ccaagaaatc
    11041 tctgatacct tgactgtcat ggcaagcgag gtgaattagt atgtttcgat taaccaataa
    11101 gttagcgata tcgaacctga ttaaaaaccg caaactctac tatccctttg cactggctgt
    11161 tctcttggca gtcaccatca cctatctctt ttactcccta accttcaatc caaagattgc
    11221 ggaaatccgt ggaggaacca ccattcaagc aacacttgga tttggtatgt ttgtcgttac
    11281 ccttgcgtca gccattatcg tcctctatgc caatagtttt gtcatgaaaa accgttccaa
    11341 gaaactgggt atatatggca tgttaggctt ggagaagcgc catctaatca gtatgacctt
    11401 taaggagtta gtgctatttg ggattctaac tgttggagca ggaatcggta ttggagcctt
    11461 gtttgacaag ttgattttcg ctttcctact caaactgatg aaattgaagg tggaactggt
    11521 cgctaccttc cagatgaaag ttgtcattac agtacttctt gtcttcggtt tgattttcct
    11581 aggcctcatg ttcctgaatg cccttcgaat cgcccgtatg aatgccctcc agctctcacg
    11641 tgagaaagct agcggagaga aaagaggtcg tttcctacct ctccaaacta ttcttggttc
    11701 cataagttta gggattggct attatcttgc ccttacggta accgatcctc ttacagccct
    11761 aacaattttc ttcctagctg ttttgctggt tatctttggt acttatctat tgtttaatgc
    11821 agggattaca gtcttcctac aaatcttaaa gaaaaacaag aaatactatt accaacctaa
    11881 taacctcata tctgtttcca acttgatttt ccgtatgaag aaaaatgcgg ttggactagc
    11941 aaccatcgct attttgtcaa caatggtttt ggtaaccatg tcagcagcga caagcatttt
    12001 caattccgca gaaagcttta aaaaagttct aaatcctcat gattttgggg tttcagggca
    12061 aaatgttgaa aaagaagatt tggacaaact cttgagccag tttgcaagtg acaaaggtta
    12121 tagtgtcaaa gagaaagaag tacttcgtta cagtaacttt ggtattgcaa atcaagaagg
    12181 aaccaagtta actatttttg aaaaaggaca aaaccgtgtc caacccaaaa cagttttcat
    12241 ggtatttgac caaaaagatt atgaaaatat gactggtcaa aaactgtctc tatcaggaaa
    12301 tgaggtcgga ctctttgcaa agaatgaggg agttaaagaa cagaaagctc taactctaaa
    12361 tgatcatcaa ttttctgtca aagaagaatt tactaaagat tttattgtca accatgttcc
    12421 aaatcagttt aatattttga ctgctgatta caattacctt gttgtacctg atttacaagc
    12481 ctttttgaac caattcccag attcggatat ctataatcag ttttacggtg gtatgaatgt
    12541 aagtatcagt gaagaagagc aactcaaagt cgctgaagaa tatgaaaaat acttacaaaa
    12601 gtttaatgct caattaaaca ctgaaggtaa ctatgtgtat ggtagcactc tagcagatgc
    12661 tagtgctcaa atgagtgtcc tctttggcgg tgtcttcttt attggtattt tcctatccat
    12721 tatctttatg gtcggaaccg ttctggtcat ctactacaaa caaatttctg aaggctatga
    12781 agaccgtgaa cgctttatta tcttgcagaa agtcggttta gatcaaaagc aaatcaagca
    12841 aatcatcaac aaacaggttt taactgtttt cttccttcct ttgctttttg ccttcataca
    12901 tctagccttt gcctaccata tgcttagcct gattttaaaa gtgattggtg tactggatac
    12961 gactatgatg ttgatcgtga ccttgtctat ctgcgctatc ttcctcatcg cctatgtgct
    13021 gattttcatg attacttcaa gaagttatcg caagattgtg caaatgtaaa aaagatacct
    13081 cgacttcaaa atcgaggtat ttcttgtatt ctaaatgctg aaaagttgtt cgagcaggaa
    13141 ggtaactccc atggtcaaga gaccaatagc taggttccga atcatagctg ttctagccgg
    13201 agcctttcca agtctggcac tagtgtaacc agtgagaaga agggccacac cgacaataag
    13261 gacagtagca gggatgcgat attcacttgg gaatatggtc actgacagca ttggaggcaa
    13321 acttctaagg aaaaaggcaa cgaagctaga aatggcagcg tgccaaggat tggtaaattc
    13381 ttcatactca atcccatatt tttcctctac cagagccttg agtggatttt taagaaagat
    13441 cttattagtc aagagttggg cagaagtttt gcattctcca ttttggatat aagcagcata
    13501 gagggatttt ttggctagtt ccctatcttg gtctagcaag agtttttctc gcgaaacggc
    13561 agcttcctcg gtatcttttg gagttgaaac ggatacatat tctccaccag ccattgaaaa
    13621 ggcaccagct aagatagccg caaaacctga taaaaagata atccagatat tggtcgtggc
    13681 actggcaact ccgataacca caccagcaat ggaaataatt ccattgttag catcaagaac
    13741 acccgcacgc aggatattta aacgacctgc aaaatttgaa tcaatttcgt gatttgtttc
    13801 tgacgctaaa tttcaagttc aagttagcca tcaagaagtc ttctctgggt gacttgtagt
    13861 ccaagtattt tttaggatag ttgttgatcc acttttcgat gaatgcgact tctttgggag
    13921 tcattttctt ggttccctta ggtaaccatc tacgaatgag cctgttgcga ttctcattag
    13981 ttcccctttc ccaagaggca taggggtgcg cataatagat gtgctcctca gaaaatacat
    14041 ca
//
LOCUS       DBEJKC010000051        13631 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.051, whole genome shotgun sequence.
ACCESSION   DBEJKC010000051 DBEJKC010000000
VERSION     DBEJKC010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13631
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.051"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            288..1124
                     /locus_tag="ACL3G6_001624"
     CDS             288..1124
                     /locus_tag="ACL3G6_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGR0546118.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIIIGKGIAFGKRKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLKGYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            1160..1477
                     /locus_tag="ACL3G6_001625"
     CDS             1160..1477
                     /locus_tag="ACL3G6_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0546119.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            1477..3168
                     /locus_tag="ACL3G6_001626"
     CDS             1477..3168
                     /locus_tag="ACL3G6_001626"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HGR0546120.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VEAAQNTITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            3377..4783
                     /gene="lacG"
                     /locus_tag="ACL3G6_001627"
     CDS             3377..4783
                     /gene="lacG"
                     /locus_tag="ACL3G6_001627"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGR0546121.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTDYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            4826..5083
                     /locus_tag="ACL3G6_001628"
     CDS             4826..5083
                     /locus_tag="ACL3G6_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HGR0546122.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDELEEFKNLFLNFINPEGWDTISFDSDFMPFQQS"
     gene            complement(5362..6123)
                     /locus_tag="ACL3G6_001629"
     CDS             complement(5362..6123)
                     /locus_tag="ACL3G6_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0546123.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(6305..7267)
                     /gene="nrdF"
                     /locus_tag="ACL3G6_001630"
     CDS             complement(6305..7267)
                     /gene="nrdF"
                     /locus_tag="ACL3G6_001630"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HGR0546124.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(7455..9614)
                     /gene="nrdE"
                     /locus_tag="ACL3G6_001631"
     CDS             complement(7455..9614)
                     /gene="nrdE"
                     /locus_tag="ACL3G6_001631"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HGR0546125.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(9695..9913)
                     /gene="nrdH"
                     /locus_tag="ACL3G6_001632"
     CDS             complement(9695..9913)
                     /gene="nrdH"
                     /locus_tag="ACL3G6_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HGR0546126.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            10264..10527
                     /locus_tag="ACL3G6_001633"
     CDS             10264..10527
                     /locus_tag="ACL3G6_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HGR0546127.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            10533..12266
                     /gene="ptsP"
                     /locus_tag="ACL3G6_001634"
     CDS             10533..12266
                     /gene="ptsP"
                     /locus_tag="ACL3G6_001634"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HGR0546128.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            12520..>13631
                     /locus_tag="ACL3G6_001635"
     CDS             12520..>13631
                     /locus_tag="ACL3G6_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HGR0546129.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSANDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRENLSNLRTYRRQNSDNTPRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLIFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEERIARIIPLRYRSNHWVPDSRPEEPSP"
BASE COUNT         4211 a         2508 c         2797 g         4115 t
ORIGIN      
        1 ttttattttt ctgtcttcct gtttttgttt tgatttacaa aaataaataa aaacagagcc
       61 tctgtttgat gaattttaga acatagttaa gttttaaaaa aagttgtatg taaaggttta
      121 caaaacaacc gacttgtgct atacttaaat cacaagttaa tacaaggtga gtgttactaa
      181 gtaatattag gcatgatcac aggtgaatta gaaatcagct gattttctag ttcatttgtg
      241 gtcatttttt gtactcatat acctttaaga tataaaagga ggttgacatg tatcgaattc
      301 taaatccaat gaatcacaat gtctcgcttg tcagaaatga taagggagaa gaggtgatta
      361 taattggtaa ggggattgca ttcggaaaaa ggaaggggga tttgattgct gaaaatcagg
      421 ttgagaaaat ctttcggatg aagaccgaag agtccagaga aaactttatg gctcttctca
      481 aagatgttcc gcttgatttt atcacagtga cctatgaaat cattgataag ctatcaaaga
      541 aatatcatta tccgattcaa gagtatctct atgtaacctt gacagatcat atttactgtt
      601 cttatcaagc tctaactcaa ggaaggtaca aggatagtaa tctgccggat atttccgcta
      661 agtatcctgt cgcttttcaa atcgcaaatg aagcttttga aatttaccgt cagaagctag
      721 cagatcattt tcctgaggac gagattattc ggattgctta tcatttcatc aatgccgaag
      781 gtgaaaatga agtggaactt gtggagtcga ttgataagag gaaagaaatt ctcaggaatg
      841 ttgaagaagt gctaaagggt tatgcaattc aacgaaccaa aaaaaataat catttctatg
      901 atcgctttat gattcatttg aattatttct tggattattt agacagatct agagatgata
      961 accaatcact tctggatatg gaagatcata ttaaacaatc ctatccaaaa gccttcgaga
     1021 ttggttccaa gatctatgat gtgattacgc aacatacggg tcttgatttg tataaaagtg
     1081 aacgagttta tctagttcta catatccaac gtttattgtc ataaaaattt atttaaaact
     1141 atataaggag aattctatca tgaatagaga agaagtaaca ttgttaggtt ttgaaatcgt
     1201 agcctatgct ggcgatgctc gttcaaaact attggaagcc ttgaaggctg ctgaagctgg
     1261 tgattttgaa aaagcggacg ctctggtaga ggaagctggt agctgtattg cagaggctca
     1321 ccacgcgcaa acaagtctat tgactaagga agcttctggt gaggacttag cgtatagtgt
     1381 gaccatgatg catggccaag accacttgat gacaactatc ttgttaaagg atttgatgca
     1441 ccatttgatc gaactctata agagaggagt taaataatga acaaactaat tgcatttatc
     1501 gagaaaggaa agcctttctt tgagaaacta tctcgtaata tctatcttcg tgctattcgt
     1561 gatggtttca ttgcaggtat gcctgttatt ctcttctcaa gtatctttat cttgattgcc
     1621 tttgtaccaa actcatgggg ctttaaatgg tctgatgaag ttgtagcctt tctgatgaaa
     1681 ccttatagct attctatggg tattctggct ctcttggtag ctggtacaac agctaagtca
     1741 ttgactgact cagtaaaccg gagcatggaa aaaaccaatc aaatcaacta tatgtcaacg
     1801 ctgttagcag cgattgttgg tttgttgatg ttggcagctg atcctatcga aagtggtcta
     1861 gctactggat tcttggggac aaaaggtttg ctttcagcct tccttgctgc cttcgttact
     1921 gtagccatct ataaggtttg tgttaagaac aacgtcacta ttcgtatgcc tgacgaagtt
     1981 ccaccaaata tctcacaagt ctttaaagat gtgattccat tcactctatc agtggtttct
     2041 ctttatgctc ttgatttact agctcgtcat tttgttggtt ctagtgtggc agaatcaatc
     2101 ggtaaattct tcgcaccact cttctcagca gcagacggat accttggtat taccattatc
     2161 tttggtgcct ttgccttctt ctggtttgtg ggtattcatg gtccatctat tgttgaacct
     2221 gctatcgcag cgattaccta tgcaaatgct gaagtcaact tgaaccttct ccaacaaggt
     2281 atgcatgctg ataaaatcct tacttcagga actcaaatgt ttatcgttac tatgggaggt
     2341 actggtgcga cactggttgt tccattcatg ttcatgtggt taacaaaatc aaaacgtaac
     2401 cgtgcaatcg gacgtgcttc agtagttcca actttctttg gtgtaaatga accaatcttg
     2461 tttggtgcac cacttgtatt aaatccaatc ttcttcattc catttatctt tgctccaatc
     2521 gcaaacgtat ggattttcaa attctttatt gaaactcttg gaatgaactc attcactgct
     2581 aatctaccat ggacaactcc agctccacta ggtctagttc ttggaactaa cttccaagtg
     2641 ctatcattca ttcttgctgc ccttctaatc gtggttgacg ttgtcattta ctatccattc
     2701 cttaaggtct atgatgaaca aattcttgaa gaagaacgtt caggtaagtc taatgatgaa
     2761 ttgaaagaaa aagttgctgc aaacttcaac actgcaaaag cggatgctat tcttgaaaaa
     2821 gcgggtgtag aagcagcaca aaatacaatc actaaagaaa caaatgtcct cgttctctgt
     2881 gcaggtggag gaacaagtgg tctccttgca aatgctttga ataaggcagc agcagaatac
     2941 aatgtccctg tgaaagcagc agcaggcggc tatggtgctc accgtgaaat gttaccagag
     3001 tttgatcttg ttatccttgc ccctcaagtt gcttcaaact ttgaagatat gaaggcagaa
     3061 acagataagc tcggtattaa actagcgaaa acagaaggcg ctcaatacat caaattaact
     3121 cgtgatggaa aaggtgctct tgcattcgta caagcgcaat tcgattaagg ctagagactc
     3181 tgaaatagtc tcctatcgtt acggaaatcg ctatggcgaa tttcctatta ttaattcgtc
     3241 ggtaaaaaga tatcgttttt acctcctcat gtcacaattc ggtgacttgg tacaagaagt
     3301 gagatggaga aggatggctc actgactcct ctcctctcac ttttacttta tttaaatcaa
     3361 gaaataggtg aaaaaaatga caaaaacact tccaaaagac tttatttttg gtggcgcaac
     3421 agctgcctat caagcagaag gtgctacaca tactgatggt aaaggaccag tagcgtggga
     3481 taaatatctt gaagataact actggtacac tgcagaacca gccagtgatt tttacaatcg
     3541 atatccagtt gacctcaagc tagcagaaga gtatggtgtc aatggtattc gaatttctat
     3601 tgcttggtca cgtattttcc cgactgatta cggccaagta aatgctaaag gtgttgagtt
     3661 ttatcataat ttatttgcag agtgtcacaa acgtcatgtt gagccttttg taactcttca
     3721 tcactttgac acgccagaag ctctccactc aaatggagac ttcttaaacc gtgaaaatat
     3781 cgaacatttt gtagactacg ctgccttctg ttttgaagaa tttccagaag taaactattg
     3841 gacaaccttt aatgaaattg gaccaatcgg tgatggtcaa tatttggttg ggaaattccc
     3901 tccaggtatc cagtacgacc ttgccaaagt ctttcaatca caccacaata tgatggtgtc
     3961 tcatgcacgc gcggtaaaat tgtacaaaga gaaaggctat aaaggggaaa ttggtgttgt
     4021 tcacgccctg ccaactaaat atcctctaga tcctgaaaat ccagcagatg ttcgtgcagc
     4081 tgagttggaa gatatcatcc acaataaatt catcttagac gcaacttatc taggtcgcta
     4141 ttcagctgaa accatggaag gtgtcaacca tatcttatca gtcaatggtg gtagcttgga
     4201 tcttcgtgaa gaagatttta cagcattaga agctgcaaaa gacttgaatg atttcctagg
     4261 aatcaactac tatatgagtg actggatgga agcctttgat ggagaaactg aaattatcca
     4321 taatggtaaa ggtgaaaaag gaagctctaa gtatcaaatc aaaggtgttg gtcgtcgtgt
     4381 agctcctgac tatgtaccac gcacggattg ggattggatt atctaccctc aaggtttgta
     4441 tgaccaaatc atgcgtgtga agaaagatta tcctaactac aagaagattt acatcactga
     4501 aaatggtctc ggctataaag atgagttcgt tgataacact gtttacgatg atggtcgtat
     4561 tgattacgtg aaacaacact tggagatctt gtctgatgcg attgcagatg gagctaatgt
     4621 aaaaggttac ttcatttggt cattaatgga tgtcttctca tggtcaaacg gttatgagaa
     4681 acgttatggt ctcttctacg tagattttga aactcaagaa cgttatccta agaaatcagc
     4741 tcactggtac aagaaagtag cggaaactca gattatagac tagtagaatt agtcattaga
     4801 tatagaattt tagtgagtca aaaagatgtt caaagatttt atccaatcta tttatgaaaa
     4861 agtttatatt ataaatttcg aaaaatgctc tcaaataccg tgtttgacga gtgaagaatt
     4921 gaaaagtctt ggaaaatggt atgtctcgac tggtaaagaa tggatttgtc attcagatga
     4981 tgagctggaa gaatttaaaa atctattttt aaattttatc aatcctgaag gatgggatac
     5041 tatctccttt gattcagatt ttatgccgtt tcaacaatcg taaccaattt ctcaaaaaag
     5101 ttaaatctta tatttagtac tctgtaaaac tcttatctaa tcacgttgct tatactcaat
     5161 gaaaatcaaa gagcaacttt aaactaggaa gcgagtcgca gatttctcaa tgcatagctt
     5221 tgaggaattg ggcaaaaagt ctttgatata gaaaaacgca tagtatcagg tgttgaaaca
     5281 cctgatacta tgcgttttat tgtgggaaga tttacttttt ttcttctgaa attgagttgt
     5341 tacccaggct ctttcagttt attaaggctt gatgacttta atgtgtttag atagcttaaa
     5401 aaggattgaa tcacttagtt tagaatctga aacaatagta tcaagatttg atacattata
     5461 aaaagtataa aaatcaaact tattgaactt gctatgatct gcgagtaaat attttttatt
     5521 agaattattt aaagcgatgc gttgagcctc tccctcttcc tcgctaaaag tagctagagc
     5581 tccgttttga ataccattac agctaacgaa agctttagaa aattggagat tagagagatt
     5641 ttgtagggtc aatgtaccaa caaaagcacc tgtaatatcg cgataatttc cacctattaa
     5701 aatcaaatct gttaattttc gttcgcttaa aatcagaaaa acaggtagac tgttggttac
     5761 gacgcggata ttgtcaatag gcaactcacg cgcaaaaaac tctaatgttg ttcctggtcc
     5821 aatgaaaata gtttctcttt cttctactag actgcctgca aaatgggcta tttcttgttt
     5881 ttctgccgtt tggagggctt gtttttcaat atttgatcgc tcattagtca aaagggagtt
     5941 ggttcgaagt ttttcagctc caccatgcac acgaatcagc aaatctttat cagctaattc
     6001 ctgtaaatag cgccttgcag tcatatctga aacggctatt tcgtccataa tctgtttaac
     6061 tgttatggtt cctttactat ttactatctc taaaattttg gctaattttt cttgtttgag
     6121 catattatca cctcgtttcc tactactatc ttaccataaa caaactcatc attcaaatac
     6181 aaaaacaaca aaatgaaaca aaaacaaaaa tatcgaagtt tgttttcaaa actttcgata
     6241 tttttgttgg gttataactt tgatgtttct agtttacttt ttgatgattg agagtgatgg
     6301 agaattagtc taaaccgtag ttatagtcat cgtcttgcat ggcttcaact tcgccaagaa
     6361 ggtaaccatt tccgacttga gagaagaagt catggttgga agttcctgtt gaaataccgt
     6421 tcataacgat tgggttgaca tcttcagctg aatctgggaa aagtggatct tgtcccatgt
     6481 tcatgagagc tttattggca ttgtagcgaa ggaaggtttt aacctcttca gtccaaccaa
     6541 caccgtcata aagactctct gtgtagcctt cttcattttc ataaagagta tagagtaggt
     6601 cgtacatcca ttctttgagt ttttcttgct cttcttcagg caattcattg aaaccaagtt
     6661 ggaatttgta accaatgtag gttccgtgaa cagactcgtc acgaataatc aatttaatga
     6721 tttctgcaac gttggcaagt ttgttgttac cgagatagta gaggggagtg aagaaaccag
     6781 agtagaagag gaaggtttcg aggaagacgc tggcaacttt cttttcaagt gggctgccgt
     6841 ttaggtagat ttcgttgaca atctcagcct tcttttgtag gtaaggattg gtattggtcc
     6901 attcgaaaat ttcttcaatc tcagccttag tattcaaggt agaaaagatt gatgagtaag
     6961 atttagcgtg gacagattcc ataaattgga tgttattgaa aacagcttcc tcatgtggtg
     7021 tacggatgtc tgcgcgaagg gcttgaaccc cagtttcaga ttgcatagtg tcaagaaggg
     7081 ttaaaccacc aaaaactttt ccgaccaagt ctttctcttt gttagatagc tttctccagt
     7141 catccaagtc gtttgataag ggaatacgtg tatcgagcca aaattgctcc gtcagttttt
     7201 cccaagttga tttgtcgatg acatcttcga tggcattcca gttaatggct ttgtagtaag
     7261 tttccattta aaatctcttt ctgtgtttag tattgcgaac tcacaattat ttctacttta
     7321 ccataattct ataggagtat cgcacaaaaa gtcggaagcc cgacttttaa aatgttacat
     7381 aaattatgtt atgacatagt agatttgatt ttatcagtgc tgcttaggga aaaatagtgt
     7441 ttctatgcta gaaactaaat cacacagctt tcacattggt tggcgccgac ttctccaccg
     7501 tcatctgtaa aggtacggac gtagtagata gacttgattc ccttgttaaa ggcatagtta
     7561 cgaaggatgg acaaatcacg tgtcgtttgt ttattttccc tcttccattc gtaaaggcct
     7621 tttggaatgt cactacgcat gaagagggtg agtgaaagtc cttgatccac gtgttcagtc
     7681 gcagcagcgt aaacatcgat gactttacgc atatccatat cgtaggcaga agtgtagtaa
     7741 ggaatggttt ctgtagacaa gccagcagca gggtagtaga ttttaccaat tttcttctct
     7801 tggcgttctt cgatacgttg cgtaatcggg tggatagaag cagaaacgtc gttgatatag
     7861 ctgatagaac catttggcgc tacagcaagg cgattttggt ggtaaagacc atcttcttga
     7921 accttgtcgc gaagttcagc ccaatcagca acaccaggga taaagacatt tttgaagagt
     7981 tctttaacac ggtctgatgt tggaacaaat tcaccagtta catacttgtc aaagtaactt
     8041 ccgttagcat agtctgattt ttcaaagttg tggaaggtaa taccacgttc acgcgcaata
     8101 ttgtttgact ctaccaaggt ccagtagttc ataagcataa agtagatgct tgtaaattca
     8161 acagactcag gtgaaccata ttcaatgagt tgttgggcaa ggtagctgtg cagtcccatg
     8221 gcaccgagac caaaggtgtg ggcttggcta tttccatggt caatcgttgg tacagctacg
     8281 atatgtgaac tatctgtaac gaaagtaagg gcacgaacca tagcacggat agaacgacca
     8341 aaatcaggtg aagtcatcat gttaaccacg ttggttgaac ccaggttaca tgaaacatct
     8401 gttcccattt gaaggaattc ttgagcatcg ttgatcaagc ttggttcttg aacttgaaga
     8461 atctcagaac acaagttact catgataatc tttccatcaa caggatttgc acggttagcc
     8521 gtatcgatgt tgactacata aggatagcca gactcttgtt gcaatttaga gatttcagtt
     8581 tccaaatccc gcgccttgat ttttgtcttg cgaatatttg gatttgcgac caattcatcg
     8641 tatttttcag taatgtcgat gtaattgaat ggcacaccgt attctttttc tacagagtaa
     8701 gggctgaaga ggtacatttc ttcattttta cgagccaatt cgtagaattt atcaggtact
     8761 acaacaccaa gtgatagagt cttgacacgt actttttcat cagcgttttc tttcttagtt
     8821 gaaaggaaag cgatgatatc tgggtgaaag acgttgaggt agacaacacc ggcaccttga
     8881 cgttgcccca attggttgga gtaagagaag ctgtcttcaa aaagcttcat aacaggaacg
     8941 acacctgaag cagctccttc atagcctttg ataggtgcac cagcttcacg aaggttgctg
     9001 agggtaattc ccacaccacc accaatacgt gaaagttgaa gagctgagtt gatagaacgt
     9061 ccgatagagt tcatatcatc cgtcacttgg attaggaaac aagataccaa ctccccacgg
     9121 cgagcacgtc cagcattcaa gaaggaagga gtagcaggtt ggtagcgttg gtggatgatt
     9181 tcattggcaa tatcgattgc aacagcttca ttcccatcag cgaaataaag ggcgttgaag
     9241 aagacacggt cttccatatt ttcaagatag tattcaccgt cattagtctt taaggcatat
     9301 tgattgtaaa atttataagc tgccatgaat gacttgaatt ggaagttttg gtctttgata
     9361 aattgagcca attcttccaa gaactctgga cggtatttct tgataaaggc tgtttcgatg
     9421 tagttgtgtt caatgaggta attgattttg tctttgattg aatcaaaaac catagtgttt
     9481 ggaactacat tttctttaaa gaaagcatcc aaggcttcct tgtctttatg aagcatgatt
     9541 tgtccattaa caggacggtt aatttcgtta ttaagacgga agtaagtcac gtcttcaaga
     9601 tgttttaatc ccataaaatt tcccttatct aattacaaaa gaaaggcttc taagttagcc
     9661 ctaaaagcag ttttttctgg atgatgtact aagattatgc taattgcttc agttttcctg
     9721 gttggaaacc tgaaaagact tcagttggtg tttggataac aggagctgcg ctaaaaccga
     9781 gctctttaac ttgatcgacg tactcaggtt gctcatcaag attgatttca cgataagaga
     9841 cattattact gtccaagaaa cgcttggtca ttttacattg gacacaattg tttttagaat
     9901 aaacggttac cattgtgtaa ctcctcttca aaatttaata ctatcttagt atatcagaaa
     9961 ataaaatttt gtcaatgatt tgaactaaat atagtggtgt tcttttgttg tttttatata
    10021 taaacacaat atatagtgtt tgtgttgtga aatagcaatg attatcctat aaattgtttt
    10081 tgaagaaact atatcctgtg ttttgttatc taggatagaa gattttcagc aagttatctg
    10141 aaaggaaatt gaaggaaaat ccagaaaatg cttgaaaaaa atcctagaag atggtataat
    10201 actaaattgt aagggttatc acatataact caaaaaaaga aagaacaaaa ggagagtcaa
    10261 actatggctt ctaaagattt ccacgtagtg gcagaaacag gtattcacgc acgtccagca
    10321 acattgttgg tacaaactgc tagcaaattt gcttcagata tcactcttga gtacaaaggt
    10381 aaatcagtta accttaaatc aattatgggt gttatgagtc ttggtgttgg ccaaggtgct
    10441 gacgtaacta tctcagctga aggtgcagat gcagatgacg ctatcgctgc aatctcagaa
    10501 acaatggaaa aagaaggatt ggcataaggg aaatgacaga aatgcttaaa ggaatcgcag
    10561 catctgacgg tgttgcagtt gcaaaagcat atctactcgt tcagccggat ttgtcatttg
    10621 agactattac agtcgaagat acaaacgcag aagaagctcg ccttgatgcc gctctacagg
    10681 catcacaaga cgagctttct gttattcgcg agaaagcagt aggtacgctc ggtgaagaag
    10741 cagctcaagt ttttgatgct cacttaatgg ttcttgctga cccagaaatg atcagccaaa
    10801 tcaaggaaac tatccgtgcg aagaaagtga atgcagaagc aggtctgaaa gaagttacag
    10861 atatgtttat cactatcttt gaaggcatgg aagacaaccc atacatgcaa gaacgcgcag
    10921 cggatatccg cgacgtgaca aaacgtgtat tggcaaacct tcttggtaaa aaattgccaa
    10981 acccagcttc tatcaatgaa gaagtgattg tgattgcgca tgacttgact ccttcagata
    11041 cagctcaatt ggacaaaaac tttgtaaaag cttttgtaac caacattggt ggacgtacaa
    11101 gccactcagc tatcatggca cgtacacttg aaattgctgc tgtattaggt acaaacaaca
    11161 tcactgaaat cgttaaagac ggtgacatcc ttgctgttaa cgggatcact ggagaagtga
    11221 ttatcaaccc aacagatgaa caagcggcag aatttaaagc agctggtgaa gcctatgcga
    11281 aacaaaaagc tgaatgggca cttttgaaag atgctcaaac agtgactgct gacggtaaac
    11341 acttcgagtt ggctgccaat attggtactc caaaagacgt tgaaggtgtt aacaacaacg
    11401 gtgcagaagc tgttggactt taccgtacag agttcttgta catggattct caagacttcc
    11461 caactgaaga tgagcagtat gaagcataca aggctgttct tgaaggaatg aacggtaaac
    11521 ctgttgtcgt tcgtacaatg gatatcggtg gagataagga acttccttac ttcgatatgc
    11581 ctcacgaaat gaacccattc cttggattcc gtgctcttcg tatctctatc tctgagactg
    11641 gagatgctat gttccgcaca caaatccgtg ctcttcttcg tgcgtctgtt cacggtcaat
    11701 tgcgtatcat gttcccaatg gttgcgctct tgaaagaatt ccgtgcagcg aaagcagtct
    11761 ttgatgaaga aaaagcaaac cttcttgctg aaggtgttgc agttgcggat aacatccaag
    11821 ttggtatcat gatcgagatt cctgcagcag ctatgcttgc agaccaattt gctaaagaag
    11881 ttgacttctt ctcaattggt acaaacgact tgatccaata tacaatggca gcagaccgta
    11941 tgaacgaaca agtttcatac ctttaccaac catacaaccc atcaatccta cgcttgatta
    12001 acaatgtgat caaagcagct cacgctgaag gtaaatgggc tggtatgtgt ggtgagatgg
    12061 ctggtgacca acaagctgtt ccacttcttg tcggaatggg cttggatgag ttctctatgt
    12121 cagcaacatc tgtacttcgt acacgcagct tgatgaagaa actcgacaca gctaagatgg
    12181 aagagtacgc aaaccgtgcc cttacagaat gctcaacaat ggaagaagtt cttgaacttc
    12241 aaaaagaata cgttaatttt gattaatcga aaaatccctg caactcagtt acagggattt
    12301 ttttgatatt ttaaaaagaa ttttcaagaa aatctttctt atagaaagtc caaccttgaa
    12361 aaagtagtgg tcagaacaaa aaatacttaa atggttcata aaattcttga caagttggag
    12421 atttaggagt aaactattaa ccagttaagt aatagagagg agtttctgca atttagaaat
    12481 gaattgcaac tagaaatatc aaatagaaag agagtttcga tgaaaattaa taagaaatac
    12541 cttgttggtt ctgcggcagc tttgatttta agtgtttgtt cttacgagtt gggactgtat
    12601 caagctagaa cggttaagga aaataatcgt gtttcctata tagatggaaa acaagcgacg
    12661 caaaaaacgg agaatttgac tcctgatgag gttagcaagc gtgaaggaat caatgctgag
    12721 caaatcgtca tcaagataac agaccaaggc tatgtgactt cacatggcga ccactatcat
    12781 tattacaatg ggaaggttcc ttatgacgct atcatcagtg aagaattgct gatgaaggat
    12841 ccaaactacc agctaaaaga cgaggatatt atcagtgaaa tcaagggtgg ttatgttatc
    12901 aaggtagatg gaaaatacta tgtttacctt aaggatgctg cccacgcgga taatgtccgt
    12961 acaaaagaag aaatcaatcg gcaaaaacaa gaacatagtc agcatcgtga aggagggact
    13021 tcagcaaacg atggtgcggt agcctttgca cgttcacagg gacgctacac cacagatgat
    13081 gggtatatct tcaatgcatc tgatatcatt gaggacacgg gtgatgctta tatcgttcct
    13141 cacggcgacc attaccatta cattcctaag aatgagttat cagctagcga gttggctgct
    13201 gcagaagcct tcctatctgg tcgggaaaat ctgtcaaatt taagaaccta tcgccgacaa
    13261 aatagcgata acactccaag aacaaactgg gtaccttctg taagcaatcc aggaactaca
    13321 aatactaaca caagcaacaa cagcaacact aacagtcaag caagtcaaag taatgacatt
    13381 gatagtctct tgaaacagct ctacaaactg cctttgagtc aacgccatgt agaatctgat
    13441 ggccttattt tcgacccagc gcaaatcaca agtcgaaccg ccagaggtgt agctgtccct
    13501 catggtaacc attaccactt tatcccttat gaacaaatgt ctgaattgga agaacgaatt
    13561 gctcgtatta ttccccttcg ttatcgttca aaccattggg taccagattc aagaccagaa
    13621 gaaccaagtc c
//
LOCUS       DBEJKC010000052        13193 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.052, whole genome shotgun sequence.
ACCESSION   DBEJKC010000052 DBEJKC010000000
VERSION     DBEJKC010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13193
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.052"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..531
                     /locus_tag="ACL3G6_001636"
     CDS             <1..531
                     /locus_tag="ACL3G6_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0546130.1"
                     /translation="YNISKSRVDNLLKRVGLYDSRKMVAGKLSTGMRQRMLLARALIN
                     KPAVLFLDEPTSGLDPTTSRTIHELILELKTAGTTIFLTTHDMNEASLLCDYVALLNK
                     GKLVEQGAPSELIQRYNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEP
                     TLEDIFITLTGGKLNA"
     gene            524..1237
                     /locus_tag="ACL3G6_001637"
     CDS             524..1237
                     /locus_tag="ACL3G6_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0546131.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFCKYLMETQG
                     KVNDQQELVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNETLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(1439..1651)
                     /locus_tag="ACL3G6_001638"
                     /pseudo
     CDS             complement(1439..1651)
                     /locus_tag="ACL3G6_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006269888.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            1972..2673
                     /gene="pyrF"
                     /locus_tag="ACL3G6_001639"
     CDS             1972..2673
                     /gene="pyrF"
                     /locus_tag="ACL3G6_001639"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HGR0546132.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QLIKQATNPDFICLTPGIRPQGAAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            2707..3339
                     /gene="pyrE"
                     /locus_tag="ACL3G6_001640"
     CDS             2707..3339
                     /gene="pyrE"
                     /locus_tag="ACL3G6_001640"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HGR0546133.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            3800..3922
                     /locus_tag="ACL3G6_001641"
     CDS             3800..3922
                     /locus_tag="ACL3G6_001641"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546134.1"
                     /translation="MYYNGGGDNYIGSGTRLAMAPQFGNHVRIHTSGSWSPDSY"
     gene            4018..4782
                     /locus_tag="ACL3G6_001642"
     CDS             4018..4782
                     /locus_tag="ACL3G6_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546135.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMVVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            4782..5534
                     /locus_tag="ACL3G6_001643"
     CDS             4782..5534
                     /locus_tag="ACL3G6_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546136.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            5544..6242
                     /locus_tag="ACL3G6_001644"
     CDS             5544..6242
                     /locus_tag="ACL3G6_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546137.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLANWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            6239..6886
                     /locus_tag="ACL3G6_001645"
     CDS             6239..6886
                     /locus_tag="ACL3G6_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0546138.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(6973..7838)
                     /locus_tag="ACL3G6_001646"
                     /pseudo
     CDS             complement(6973..7838)
                     /locus_tag="ACL3G6_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(7850..8608)
                     /locus_tag="ACL3G6_001647"
     CDS             complement(7850..8608)
                     /locus_tag="ACL3G6_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0546139.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGASGCGK
                     STLLRCLNGLESIQGGDIFLDGQSIVENKKDFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKTQGRDKKEVTEEALQLLDRVGLLDKQHSFARQLSGGQKQRVAIVRTLLMHPE
                     IILFDEVTASLDSEMVREVLELINDLAQEGRTMILVTHEMQFAQAIADRIIFLDQGKI
                     AEEGTAHAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            complement(8609..9211)
                     /locus_tag="ACL3G6_001648"
     CDS             complement(8609..9211)
                     /locus_tag="ACL3G6_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001197618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0546140.1"
                     /translation="MGISILSVLLSMMFGTVMGIIMTSHSRIIRFLTRLYLDFTRIMP
                     QLVLLFIVYFGLARNFNINISGETSAIIVFTLWGTAEMGDLVRGAITSLPKHQFESGQ
                     ALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVEVTKVGQQIIDS
                     NRLTIPTASFWIYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            complement(9188..9526)
                     /locus_tag="ACL3G6_001649"
                     /pseudo
     CDS             complement(9188..9526)
                     /locus_tag="ACL3G6_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc.;
                     incomplete; partial in the middle of a contig; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
     gene            9559..9693
                     /locus_tag="ACL3G6_001650"
                     /pseudo
     CDS             9559..9693
                     /locus_tag="ACL3G6_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            9833..11323
                     /gene="lysS"
                     /locus_tag="ACL3G6_001651"
     CDS             9833..11323
                     /gene="lysS"
                     /locus_tag="ACL3G6_001651"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HGR0546141.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKTIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            11948..13084
                     /gene="lctO"
                     /locus_tag="ACL3G6_001652"
     CDS             11948..13084
                     /gene="lctO"
                     /locus_tag="ACL3G6_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HGR0546142.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
BASE COUNT         3945 a         2297 c         2742 g         4209 t
ORIGIN      
        1 tataatatta gtaaatcacg tgttgataat ttgttaaagc gagtaggatt atatgatagt
       61 cgcaagatgg tagcaggaaa attatccact ggaatgaggc aacgaatgct tttagcacga
      121 gctcttatca acaaacccgc tgtactcttt ctggatgaac cgacctcagg tctagatccc
      181 acaacttctc gaacaattca tgagttaatt ttagaattga aaacagcagg gacaacgatt
      241 tttctaacga ctcatgatat gaatgaagca agtcttttat gtgattatgt tgccttatta
      301 aataaaggga aattagttga gcaaggagct ccttctgaac tcattcaaag atataataaa
      361 gataaaaaga ttaaggttac agattataat gggaatcaga taacttttga ttttacatca
      421 ctagaacagg tatctcaggc tgatctggaa aatatttttt caattcattc atgtgagcct
      481 actttagaag atatttttat cacattaaca ggaggaaagc taaatgctta aacggtttct
      541 ggctttggta tggttgcgtt gtcaaattat cctttccaat aagagtattt tattgcaagt
      601 tttagtgcct tttgctttca catatttttg taaatatctt atggaaacac aggggaaggt
      661 caacgatcaa caggaattag ttcttttgat gatgtgttta cctttttctt tggctttggc
      721 tgttggaagt cctataacta ttatcttgtc tgaagaaaaa gaaaagtaca atttacaaac
      781 tcttctgttg agtggtgtta aaggatccga atacatttta tcaacgatgt ttcttccttt
      841 tttgctaact tttgtgatta tgggaactac tcctcttatt ttaggagtta caattgtaca
      901 tacttttaat tatattacaa tcgttcttct aacctcttta tccatcattt tattctattt
      961 attgataggt ttaaccgcga agagccaagt agtagctcag gttatcagtc ttcctgctat
     1021 gattttagtt gctttcttac cgatgctatc tggtttggat aagacagttg cgaagataac
     1081 agattatagt tttatgggac tgtttactaa gtttttcaca aaatgggagg gattttcatg
     1141 gaatgaaact ctaattccta atctaacact acttatttgg attgttcttc tattaacttt
     1201 aattacgata actattagga aaaagaaaat ttcttaattg agttatttta atgattataa
     1261 acacaagtgg gaaggaaaaa tgaactgatc tttttgacag caattctaca gaatagtctt
     1321 attgctatat tttgatttga gtgtacgaaa aaagaaaaat aacaatagtg ctcatactaa
     1381 ttgcagaagt tttgggtgat aagataactg ataaattgca ataaaaaatg caacattttt
     1441 aaatctcctc tataagtgct tcaaaacctg tcttgtaatc caagtatttt tgggaacggt
     1501 gattaataag ctagcaaagc accattaagg attttttcgg taattgttgc caaatcggtt
     1561 taagaaaata ctcacgaaga agtccattcg cattctcatt acttcccctt tgccaagatg
     1621 aataggcatc cgcaaaataa aacagaattc ccatttgttc aattaaaggg taacaagcaa
     1681 actctttttc tctgtcctca gtgaaagtct ttaactattc ttttggaaag agtcttgtga
     1741 ggtgttcaat agcagtcaac acatacgtga ccatgttttt acttgacaag tgctagtaga
     1801 aataatagaa taatagaaaa cctttaaagc agtccagaga ggcagctaag gttagacggt
     1861 gaaagggtgg agactaccca tttttcgtgg aaccttgctg ttggcaggtt ccttttttcg
     1921 tggcttctgt tggccagact ctctcactag taaaggtaaa aggagaaacc tatgcgagaa
     1981 catcgtccaa tcattgctct tgattttcct agttttgagg cggtcaagga atttttagct
     2041 cttttcccag cagaagaaag cctttatctc aaggtaggga tggagcttta ttacgcagcg
     2101 gggcctgaga ttgtgtccta cttaaaaggt ttgggtcata gtgtcttttt ggatctcaaa
     2161 cttcatgaca ttcctaatac agtcaagtca gccatgaagg tcttgtctca gcttggtgtc
     2221 gatatgacca atgttcatgc ggctggtggt gtagagatga tgaaggctgc gcgtgaaggt
     2281 cttggaagtc aagcaaaatt gatcgctgta acgcagctga catcaacatc agaagcccag
     2341 atgcaggagt ttcaaaatat ccaaacaagc ctacaagagt ctgtgatcca ctatgccaag
     2401 aagacagctg aagcaggctt ggatggtgtc gtttgctcgg cacaggaagt tcaacttatc
     2461 aagcaggcca ccaatccaga ttttatctgt ctgacaccag ggattcgccc acagggagct
     2521 gctgttggag accaaaaacg cgtcatgacg ccagcagatg cttatcaaat tggtagtgac
     2581 tatatcgtag tgggacgtcc cattacccaa gctgaggatc ctgttgcagc ttatcatgcc
     2641 atcaaggatg aatggacaca ggactggaat taaagaacta gattagaaaa ataaaaggag
     2701 aataccatga cacttgctaa agatatcgct agccacctct tgaaaatcca agccgtttac
     2761 ctcaaaccag aggaaccctt cacttgggcg tctggtatca agtcaccgat ttacactgat
     2821 aatcgtgtga cactagccta tccagaaact cgtaccctaa ttgaaaatgg ttttgtggaa
     2881 gctatcaaag aagcctttcc tgaagtagaa gtgattgcag gaactgcaac agcagggatt
     2941 ccacacggag ccattattgc tgataagatg gacttgcctt ttgcctacat ccgtagcaaa
     3001 ccaaaagacc acggagctgg taatcaaatc gaaggtcgcg tagctcaagg tcaaaaaatg
     3061 gtagtggttg aagaccttat ttcaacgggt ggttcagttc ttgaagctgt agcagcagcc
     3121 aagcgagaag gagcagatgt acttggagtt gtagcgattt tcagctacca attgccaaaa
     3181 gcagataaga actttgcaga tgctggtgtt aaacttgtga cgctttcaaa ctatagcgag
     3241 cttatccatc tagcccaaga agaaggttac atcacgccag agggccttga tcttctaaaa
     3301 cgctttaaag aagaccaaga aaattggcaa gaaggttagg tcagtaagat aaagagagac
     3361 gaggctaccg agtctctttt accattttat ttaaaatatg ataatatttt aaataaaata
     3421 attgacaacg ctttctttta ttgatataat gaaaatgtaa tatgtatcaa attgatcaat
     3481 caactatctt gtttatcact tcttaagagg acgatgtcat gaaaagaaga aaaatatatt
     3541 ccttttttgc gtagttacaa ttgcatctag tttgtttctc cctacagttt tagctagaca
     3601 gattggaaat tatgatttaa cgttgccgcg ttggggttcg gatacaacta gtgagcttga
     3661 gaaagaaaac gcctctgctg gaattaataa tagtgacagc actggtggcg gtaaaaggtt
     3721 aaatacctct attcgtagcg cctatagtgg gtcagatatt accccggtat attcattggg
     3781 gtctggctct aggattgtca tgtactataa tggaggtggt gacaattata ttggttctgg
     3841 tactagatta gctatggcgc cacaatttgg aaatcatgta agaattcata cttcaggttc
     3901 ttggagtcca gattcttatt aacttacttg tcagagtaag ccttaaagat ggttgattgt
     3961 gggtgtagca tgaaaaaaga atgctacacc ctatttttat tataaggagg agtaaggatg
     4021 gaatttttca tttgtaatct tgtacgagtc gttcaatcac ctcggtttta tatgtcttta
     4081 tttttgaccc ttctttgcat gagtttagga aatttccttg ctttcaatgg tatttataaa
     4141 attgaaggtt tatcgatttt ttttgccgct tcttctattc gaggattttc accgattagc
     4201 ctagtagctg cacttatctg tacactgccc tattctagtc agataataga ggatgctgag
     4261 agtcattttc taacagcaca attgtgccga atttctaaaa agaggtatct agctattgta
     4321 ggtagtactg caattatttc ttcttttcta gtcttttttc tcccctattt attattatta
     4381 ggaattaatc ttttagtgac tccttatcag gaaatttata ttggagatta tagtggtgcc
     4441 ttaaaagaat tatttgattc taatcagttt ctctatagtc ttgtgacgac tctctggtat
     4501 ggagtttggg gcgctgtgtt ctctattttt ggactagcta gtgctttgct agtgaagaaa
     4561 aaattaggag ctattttcat cccagttgcc tatatggtgg ttggtggtat tttatgggct
     4621 attttagggc tatcttactt agaacctgtg acaacgctag ctttgggata tcagaaagat
     4681 atcagtcttt ccttagttag tgggcatctt gcttttattt tatttgttag ttgtttggtt
     4741 gtttatggta cattttttct acattcagag gactatgtat aatgaaacaa tttgttcaat
     4801 tttataaaaa agatttctta gcagtattgg tttattttat attactgcta tcctgtgttt
     4861 tatctagtac agtatattta ttgcgctgtc gccaatattc aatccatcca aatgtattag
     4921 aatggatttt agttttactt caagatatga cgactggagt atattgcttt ccgttcacat
     4981 atatattgtt ctttttttat ttgatgaata actattttaa taggttggag tgtcgcattc
     5041 gtctgaaatc aattaagcac tttaccagtt ttagtttcaa attagcagct cttagtacgg
     5101 ggatttggac ggcgacttta tttttattga tttttctaat tgcatttagt aatggtttta
     5161 gcttctcttt ggagataaag gaggttgatt ttttaagaga attttatggt ataagtattg
     5221 caaacaatgc tagtttcttt ataggatttt ttttctctta tatagcatac tatttctttt
     5281 tatccttact tactattagc agtttttctt ggtttaaaaa atcaaacatg agcttagtat
     5341 ttctgtttac ttttttattt gtagaatcct tattctggat ttatcagttg aacaatggga
     5401 taattggatt attgccaatt tttcagtata tggtaaattc caatccgtat gcattgattt
     5461 attggcttac attactatct atcataattc cattgactgt attttctgtt catagaaact
     5521 ggaggagagt gtaaaagttg gaaatgggaa agttaagtag tcacatgtgg aggttgaatc
     5581 agataatcta taccaagtac ttttggggtt atgttctttt ttggatattg atttgtttag
     5641 gattatggta ttggttagaa ggaaatgata gacttgttat agaaatttta aaagggccta
     5701 atctgagtca aaactctttt ttagtcttat ctatatggtt gcttcattgg tttattattc
     5761 atacattttt tctagcagtt gtatatcgta gaagagcatc cgatttcttt atggaagtga
     5821 ttcgattttc ttctattaag ctctggatta ggtatcagat ttggacctgt tttctttatg
     5881 gactcatttt aatcatggta aaagttctag tgattcaatt tatgttacag ttagcaaact
     5941 gggatatagg agttttgttt atagttgatt ctttgaatgc ttgtgtgcta tccttgcttt
     6001 gctttatgtt atacgcacta ggagcgaatg tacaaatgaa ctttgcttgc gttagtttct
     6061 ttttactcat gattgtgttt ggtggtctat ttgtaggaaa tcgaactaat tatctatttt
     6121 atattttgaa tcgagggaat ggagatatag gacgagattt atttcttcag ttgctatttt
     6181 tagtctttct ttttaaaagc attttctatt tcactcgtca aaagaggagg tttatagaat
     6241 gaatgaaata attacattaa aaaatattga gttgaaatta aaaaaaacat gtgtttttca
     6301 aaaccttaat tttagttgta aacaggggga aattatagga attactggtg cgaatggctc
     6361 aggtaaaagt gtattgttta aattaatagc tggtttatat agtccgtctt atggagaagt
     6421 gttaatcaat ggggaaaata ttgttcctga gagaaaaatt ccagctaatt tgggagcttt
     6481 gattgaagaa cctggtttta taaattatta tagtggcttt aagaatttac aatatttggc
     6541 aagcatacga ggagtagttg gtaatcagga aatcaatgat acactgaaaa tagttggtct
     6601 atatgagcaa aaagaccaga aagttaaaac ttattcgcta ggtatgagga aaaagctagg
     6661 gattgctcaa gcaattatgg agaatccctc tattctttta ctagatgaac ctatgaatgc
     6721 cttggataaa tcaagtgtag aaaatatgag aacattgttt agaaagctct ctagtgaaaa
     6781 agggacaaca attttgattg ctagtcatag tgaagaggat attcgtatct tatgtgataa
     6841 agtatatgca atagaagata aagtatgtac actgtgttca gattgaacat cttagataga
     6901 ctcaggatgt tataggtaaa atcttaaaaa gggattggag cttaaaatcc agttcctttt
     6961 aagagttaat gactaatcaa cttttccacc ttcaacaacc aggtcatctg ctttagcagt
     7021 gtcaccgtgg gttgggtgaa gtgttttttc ataggccttg tggaagaagt tttccttgct
     7081 aatttttcaa tatctttatt gatgaagtct agcaattctt ggttgccttt ttgaactgct
     7141 gccgcaatgg tatcgggatc accgagggaa gtaattccta cttcaaatcc tttattttca
     7201 agcgcccaag ctagaacttc cgtattgtca gttgaaaagg catctccacg tccgtcaaga
     7261 agagcttggt aagagtcact gtattggtcg tatttttgga gtttgatttc tggatgattc
     7321 ttttcaaaat aagtctcagc agtcgttcct tttgtgacaa ttaaggtttt accttcaagt
     7381 tgtttgacgt ctgtaatgag accagtctta ggtgatacga cacccagaga aactttcata
     7441 tatggaaggg caaaatcaac ttgtttctta cgttcgtcag ttactgtaaa gttagcaaga
     7501 gtaatatcta ccttgtttga aatcaagtat tccgcacggt tggcagcatc gactgaaatg
     7561 tatttaacct tgacaccaag gtcttgagct agttggttcc ctagttcaat atcgtagcct
     7621 tggtaagaac catcattgtc aacgtagcca aacggttttt tatctccaaa cacggcgatt
     7681 cgcagttcac cgcttttttt gatttcatcg atagtgcgag ctttggcagt tgtttttcca
     7741 gaggatgaac cagcgtttcc acctgagcta caagcagtga taaagataag ggcaaaggca
     7801 agtgctaaaa cagttaagag tggtttgaat agtttcataa gaatctcctt tatagatatg
     7861 agccaaattg gctaaagtca aagacgttta aaaattcctg ggctcgtttg gtttgcggat
     7921 tggtaaagaa ggcatgagct gttccttctt cagcgatttt cccttggtcg aggaagataa
     7981 tccggtcagc aatggcttgg gcaaactgca tttcgtgggt tactaaaatc atggtacggc
     8041 cttcttgggc caaatcattg ataagttcca gcacctcacg caccatttct gaatccagcg
     8101 aagcagtcac ctcgtcaaaa aggatgattt ctggatgcat taggagggta cggacaattg
     8161 caacacgttg cttctgtcca ccagataatt gacgggcaaa gctatgttgt ttatccagca
     8221 aaccgacacg atctagtaat tgcaaagctt cttccgttac ttctttcttg tcccttcctt
     8281 gagttttgat agggcctagg atgaggtttt gtaagacatc cagatgggga aagagttcat
     8341 aactttgaaa gaccatgcca atcttttggc gaactaggtg aaaatctttt ttattttcaa
     8401 cgatagactg accatccaga aaaatatctc caccttgaat actttctaag ccgttgaggc
     8461 aacgaaggag ggtacttttc ccacaaccag atgcccctag gatgacaaca acttcccctt
     8521 ttttaatttc tagagaaagt ccttggagga tgggattgtc tccgaaggat ttttttagtt
     8581 ccttgatttc taagatagtt tcagacattt agtttctcca atgtttttct aagtgagtgg
     8641 atagtttgga aatagggtag caaactgcga aatataagac tagaatggtt ccataaatcc
     8701 aaaatgaagc agttgggatg gtcaggcgat tgctatcgat gatttgttgt ccaactttgg
     8761 tcacttccac aaccccaatc aaaacaacta atgaagtggt tttaatcatc cgagtgacaa
     8821 gattgatagc ctgcggtagc agtcttctca agacttgtgg gatgatgatg tggtagtaaa
     8881 gttgaacatt agtcaagccg agtgcttgtc cactttcaaa ctgatgttta gggagagaag
     8941 tgatagctcc acgtaccaag tctcccattt cagctgttcc ccagagggta aaaacgataa
     9001 tagctgaagt ctcacctgag atattgatat taaagtttcg agccaagcca aagtaaacga
     9061 tgaagagtag caccagctgg ggcatgatac gggtaaagtc cagatacaat cgtgttaaaa
     9121 atcgtatgat tctagaatgg gaggtcatga tgattcccat gactgttccg aacatcatgg
     9181 ataagaggac agacaggatg gatatcccaa tcgtaacgcc caatccctgt aagattctca
     9241 ggagattatt tccttgaaag agtacttgga ttcccgaatc ctgcatggcg gagcctccta
     9301 aaaagacaag cccaagcgtt gcacagactt ctgaagatag gacaatcccg attcggggaa
     9361 gaccgaagta gagaaagaag agttgaatca aaaggggcgt attacgtgac aattcaatgt
     9421 aggctgtcgc tacttgcgcc aaaacaggga ttcgataatg tcggatgata ctaacgatta
     9481 aaccgagcag aaaggatccc aaacttcccc aaactgcaat atacaaagta aacgcttact
     9541 tatcaaggag tgcattttat gtcatacaaa acaagcaatg cagaaggtca tgtagatttc
     9601 atcaatacct atgatttgga gccaatggcg caacaagtta ttcctaaagc agcatttggc
     9661 tatatcgcta gtggggcgga agatactttc acttctttcc agtgatttta gcgtcaggtt
     9721 ctttttagtt tttaaagatt atccgtgaat ttcttgctta tttatgataa aatgggagta
     9781 tcgcaaaaaa tgactcatcg tattcaattt tgagtaaaac taggaggatc ccatgtctac
     9841 agaacatatg gaagaactaa atgaccagca gatcgttcgc cgtgaaaaaa tggctgcgct
     9901 ccgcgaacaa ggaatcgatc ctttcggaaa acgttttgaa cgtactgcaa attcacaaga
     9961 attaaaagat aaatatgcca acctcgataa agaacaatta cacgataaaa acgaaacagc
    10021 tactatcgca ggacgcttgg taaccaaacg tggtaaagga aaagttggtt ttgcccacct
    10081 tcaagaccgc gaaggccaga ttcagatcta tgttcgtaag gatgctgtcg gtgaagaaaa
    10141 ctacgaaatc ttcaaaaaag cagaccttgg tgacttcctt ggtgtcgaag gtgaagtgat
    10201 gcgtacggat atgggagaac tctctatcaa ggcaacccac atcacacact tgtctaaggc
    10261 tcttcgtcct cttcctgaga aattccatgg tttgacagac gttgaaacaa tttaccgtaa
    10321 acgttacctt gacttgattt ctaatcgtga aagctttgaa cgctttgtca ctcgttcaaa
    10381 aatcatctct gaaatccgtc gttaccttga ccaaaaagga ttccttgaag tggaaacacc
    10441 tgttcttcat aatgaagccg gtggtgctgc tgcccgtcca tttatcaccc accacaatgc
    10501 ccaaaacatt gacatggtgc ttcgtatcgc gactgagctt cacttaaaac gccttattgt
    10561 gggtggtatg gaacgtgtct atgaaattgg ccgtatcttc cgtaacgaag gaatggacgc
    10621 tactcataac cctgagttca cttctatcga agtttaccaa gcttatgcag acttccaaga
    10681 tatcatggac ttgacggaag gcattatcca acatgctgct aaatcagtca aaggcgatgg
    10741 cccagtcaac taccaaggta ctgaaatcaa gattaacgaa ccatttaagc gtgttcatat
    10801 ggtggatgct atcagagaaa ttactggtgt cgatttctgg caagacatga ctttggaaga
    10861 agctaaaact atcgctgctg agaagaaagt tccagttgag aaacactaca ctgaggttgg
    10921 tcacatcatc aatgccttct ttgaagagtt tgttgaagaa actttaatcc aaccaacctt
    10981 tgtctatgga catccagtag ctgtatctcc actcgctaag aaaaatcctg aagaccaacg
    11041 ctttactgac cgtttcgagc tctttatcat gactaaggag tacggtaatg cctttactga
    11101 gttgaacgac ccaatcgacc aacttagccg ttttgaagcc caagctaaag ccaaagaact
    11161 tggtgatgat gaagcgacag gaatcgacta tgactacatt gaagctcttg aatacggtat
    11221 gccaccaaca ggtggtttgg gaatcggtat cgaccgtctc tgcatgctcc tcactgatac
    11281 aacaactatc cgtgatgtat tgctcttccc aacaatgaaa taaattctta tcctctggct
    11341 cttaccaggg gattttttga ttcaaaaaga gactgaattt aaggagaaaa tgaagtgtag
    11401 tatattgaag ttgaaatagt acactttgat ttctaagaca ttgttagaaa ttggtttaaa
    11461 ttccctaagc aatttgtgca tgttttattt cattttacga tagtacgctg aaactgttca
    11521 aaaagtacta gaaattgact tggattcccc aattgatttg ttcagattca ctataaataa
    11581 aaaattaata agtgggatag gaagttagcg tcaactagga tagtatcttg cttaaacagt
    11641 atatatggga ctgatataag tccataggtc ctattagagg atgttctggt gtcttattca
    11701 cttgtttttt tatagtatta gtagatagaa tccgcaaata aaaaagtagt tcaaatgcct
    11761 ggcagcaaaa aatctcaacg attcacttaa tatagactaa agtttagagt ttaaggaaag
    11821 tagggctagt atattgtatg aaaaaataag atggttttta agcaaaactc ttgaaaatga
    11881 ttgaaaaaag agttattata gttgtgtagt aaaaagcaaa cgcttactta atcaaggagg
    11941 gcattttatg tcatacaaaa caagcaatgc agaaggtcat gtagacttca tcaataccta
    12001 tgatttggag ccaatggcgc aacaagttat tcctaaagca gcatttggct atatcgctag
    12061 tggggcggaa gatactttca ctttaagaga gaatatccgc gcctttaacc acaaactcat
    12121 cgttcctcat acactttgcg atgttgaaaa tccaagtaca gagattgaat ttgcaggtga
    12181 aaaactatct tcaccaatca ttatggcgcc tgttgcggct cataaattgg caaatgaaca
    12241 gggggaagtg gcgactgcgc gtggtgtgca tgagtttggt tctctttata caaccagctc
    12301 ttactctact gttgaccttc cagagatttc tgaagccctt caagggacac cccattggtt
    12361 ccaattttac tttagtaagg atgacggtat caaccgccac atcatggacc gtgtgaaggc
    12421 tgaaggttat aaagcgattg tcttgacggc agatgctact gtagggggga atcgtgaagt
    12481 ggataagcgt aatggttttg tcttcccagt tggcatgccg attgttgaag aatacctgcc
    12541 agaaggtgct ggtaaatcaa tggactttgt ttacaaatca gctaaacaac gcttgtctcc
    12601 acgcgatgta gaatttatcg ctgaatactc tggtcttcct gtgtatgtca agggaccaca
    12661 atgccgtgag gacgttgaac gttcacttgc tgcaggagct tctggtatct gggtaaccaa
    12721 ccacggtggt cgtcaaatcg acggtggacc agctgccttt gactcgcttc aagaagtggc
    12781 agaagcagtt gatagacgtg tgccgattgt ctttgactct ggtgttcgtc gtggtcaaca
    12841 cgtctttaaa gccttggctt caggagcaga cttggtagct attggtcgcc ctgttattta
    12901 tggcttggct ctcggtggta gtgtcggtgt gcgtcaagtc tttgaacact tgaatgcgga
    12961 attgaagaca gttatgcaat tgtctggagc tcagaccatt gaagatgtca aacactttaa
    13021 gctccgtcac aatccataca acccaacctt cccagttgac cctcgtgact taaaattgta
    13081 ttgataaaag agattgcctc cactgaatgt ggaggttttt cttcgtgtat tggaagaata
    13141 aattgctatc gaaaactata gtaaaatgaa ataagaatag gacaaatcaa tca
//
LOCUS       DBEJKC010000053        12802 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.053, whole genome shotgun sequence.
ACCESSION   DBEJKC010000053 DBEJKC010000000
VERSION     DBEJKC010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12802
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.053"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            92..526
                     /locus_tag="ACL3G6_001653"
     CDS             92..526
                     /locus_tag="ACL3G6_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0546143.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAARGGVVNGKELFSTDAEEEEEDFESGI"
     gene            538..1728
                     /locus_tag="ACL3G6_001654"
     CDS             538..1728
                     /locus_tag="ACL3G6_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGR0546144.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            1739..2230
                     /locus_tag="ACL3G6_001655"
     CDS             1739..2230
                     /locus_tag="ACL3G6_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0546145.1"
                     /translation="MTMPNIVMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKNVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKVALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            2245..3024
                     /locus_tag="ACL3G6_001656"
     CDS             2245..3024
                     /locus_tag="ACL3G6_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR0546146.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFVFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            3011..3829
                     /locus_tag="ACL3G6_001657"
     CDS             3011..3829
                     /locus_tag="ACL3G6_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0546147.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            3829..4122
                     /gene="yajC"
                     /locus_tag="ACL3G6_001658"
     CDS             3829..4122
                     /gene="yajC"
                     /locus_tag="ACL3G6_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGR0546148.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            4144..6045
                     /locus_tag="ACL3G6_001659"
     CDS             4144..6045
                     /locus_tag="ACL3G6_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HGR0546149.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYLVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPRSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            6105..7106
                     /locus_tag="ACL3G6_001660"
     CDS             6105..7106
                     /locus_tag="ACL3G6_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0546150.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKKLNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(7216..7551)
                     /locus_tag="ACL3G6_001661"
     CDS             complement(7216..7551)
                     /locus_tag="ACL3G6_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546151.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(7562..7804)
                     /locus_tag="ACL3G6_001662"
     CDS             complement(7562..7804)
                     /locus_tag="ACL3G6_001662"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546152.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(7820..8014)
                     /locus_tag="ACL3G6_001663"
     CDS             complement(7820..8014)
                     /locus_tag="ACL3G6_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0546153.1"
                     /translation="MNRVKEFRKELGISQLELAKNIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            8180..9130
                     /gene="rsmH"
                     /locus_tag="ACL3G6_001664"
     CDS             8180..9130
                     /gene="rsmH"
                     /locus_tag="ACL3G6_001664"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HGR0546154.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEKAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DRKPKMELVSRKPILPSAEELEANNRSHSAKLRVVRKIHK"
     gene            9142..9459
                     /gene="ftsL"
                     /locus_tag="ACL3G6_001665"
     CDS             9142..9459
                     /gene="ftsL"
                     /locus_tag="ACL3G6_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HGR0546155.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            9463..11715
                     /gene="pbp2X"
                     /locus_tag="ACL3G6_001666"
                     /gene_synonym="pbpX"
     CDS             9463..11715
                     /gene="pbp2X"
                     /locus_tag="ACL3G6_001666"
                     /gene_synonym="pbpX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HGR0546156.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKAKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            11717..12697
                     /gene="mraY"
                     /locus_tag="ACL3G6_001667"
     CDS             11717..12697
                     /gene="mraY"
                     /locus_tag="ACL3G6_001667"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HGR0546157.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNMGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLSFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
BASE COUNT         3874 a         2245 c         2905 g         3778 t
ORIGIN      
        1 tttttaaaaa aactattgac aagataaaaa taaaggatta caatggggaa tataaagtaa
       61 accggtaaac ctaaacaaga aaggagaaaa gatgaaaatt gtacttgtag ggcatggaca
      121 ttttgctaca gggatttata gttctttaca attgattgca ggcaatcaag aaaatgtgga
      181 ggcaattgac tttgtggaag gaatgtcagc agatgaactc aagcaaaaaa tcttacttgc
      241 aatttcaaat gaagaagaag ttttaatcct aagtgatctc ttgggaggat cgccattcaa
      301 ggtttcttct accataatgg gagaaaatcc agccaaaaca atgaatgttc tctcgggttt
      361 gaacttagcc atgttaatgg aagcagtctt tgctagaatg gctcatagct ttgatgaggt
      421 tgttaataaa tcagtagtgg cggcccgggg cggagtcgta aatggtaaag aattgttttc
      481 aacggatgca gaggaagagg aagaagattt cgaatcgggt atttaaaggg taaaagaatg
      541 ataaaaaagg ttacgattga aaaaataaaa tcgcctgagc gcttcttaga agtaccactt
      601 ctgacgaaag aagaagtcgg ccaggcaatc gataaggtta ttcggcagtt agaactcaac
      661 cttgactatt tcaaggaaga tttcccgacg ccagctacct ttgataatgt ctatccaatc
      721 atggataaca cggaatggac caatggtttc tggacaggag aactgtggtt ggcttatgaa
      781 tacagtcaac aggatgcatt taaaaacatc gctcataaaa atgttctttc tttcctggat
      841 cgtgtcaata agagagtaga attggatcac catgatctcg gcttcttgta cacaccgtct
      901 tgtatggctg aatataagat aaatggagat ggagaggcta gagaagcaac cttgaaagct
      961 gcagataagt tgattgaacg ctatcaagaa aaaggtggtt ttattcaagc ttggggagac
     1021 ttgggcaaga aagagcatta ccgtttgatt atcgactgct tgctcaatat ccaactctta
     1081 ttctttgctt atcaagaaac aggcgatcaa aaatactacg atattgcaga aagtcatttc
     1141 tatgcttcag ctaataatgt aatccgtgat gacgcttcgt ccttccacac cttctatttt
     1201 gatcctgaga caggtcaacc ctttaaaggt gtaacgagac aagggtatag tgatgattca
     1261 tgctgggcac gtggtcaatc atggggagtc tatggtattc ctttgactta tcgtcactta
     1321 aaagacgagt cctgctttga cttgtttaag ggtgtgacca attatttctt gaatcgtctg
     1381 ccaaaagatc atgtgtccta ttgggatttg atttttaatg atggtagtgc tcaatcacga
     1441 gattcttcag caacagctat cgccgtctgt gggattcatg aaatgctaaa acatctccca
     1501 gaggtggatg ctgacaaaga tatttataaa catgctatgc atgccatgct tcgttccttg
     1561 atcgaacatt atgcaaatga tcaatttacc cctggtggga caagtctcct ccacggtgtg
     1621 tactcatggc attcaggtaa aggagtggat gaaggcaata tctggggtga ctactattac
     1681 ctagaagccc ttatccgttt ctacaaagac tggaacctat attggtagga ggagaaatat
     1741 gacaatgcca aatattgtta tgacccgtat cgatgaacgg ttgattcatg gacaaggaca
     1801 actttgggta aaatacctag gttgtaatac ggtcattgtt gccaatgacg aagtaagcac
     1861 ggacaagatg caacaaactc tgatgaaaac agttgtgcca gactcagttg ccatgcgttt
     1921 cttccctttg caaaaggtga ttgatatcat tcacaaggct aatcctgctc aaacgatctt
     1981 tatcgttgta aagaatgtga aggatgcttt aaccttggta gaaggtggtg tccctatcaa
     2041 agaaatcaat attgggaaca ttcacaatgc tactggtaaa gagcaagtga cacgctccat
     2101 cttcctgggt gaagaggaca aggtggccct caaggaattg agccaaactc atcaagtaac
     2161 atttaatacg aaaacaactc caacaggaaa tgatggagct gttcaagtca acattatgga
     2221 ctatatttaa aagaggagat cgttatgtcg attaatgtat ttcaagcgat tttaattgga
     2281 ttatggacag ctttctgttt tagtggaatg ctgttaggaa tttacaccaa tagatgtatt
     2341 gttctgtcat ttggtgtcgg aattattcta ggtgatctgc ctactgctct tgcaatggga
     2401 gctattggtg aattggctta tatgggattc ggtgttggtg ctggaggtac tgttccacca
     2461 aacccaatcg gacctggtat ctttggtacc ttgatggcta tcactagtgc tggtaaagtc
     2521 agtccagaag cggctcttgc cctctctact ccgattgctg tggcgattca attcttacaa
     2581 actttcgcct acactgtacg tgctggtgcg cctgaaacgg cgatgaagca cttgaaaaac
     2641 cataatttga agaaattcaa gttcactcta aatgcaacaa tttggttgtt tgtctttatt
     2701 ggatttacct tgggttgctt gggcgccctt tcaatggata ccttgttgaa actcgtagac
     2761 tacattccac cggtattgct tacaggtttg acagttgctg gtaaaatgct cccagctatc
     2821 ggttttgcga tgatcttgtc agtgatggct aagaaagagt tgattccctt tgtcttgttg
     2881 ggatatgttt gtgcagctta tctaaacatc ccaacaattg gtattgcaat tgtaggtact
     2941 atctttgctt tgattgaatt ttataacaag ccaaaaacag cggatcatgt ggtagaggag
     3001 gaagcacacg atgactggat ctaacaaatt aacaaaacgt gattatctta aaacgtcttt
     3061 gcgggcattc ttttgtcaaa atggatttaa ctatagtaac tatcaagggt tgggatatgc
     3121 caatgtgatg tatcctgctt tgaaaaaaca ctatggagag gatcaggaag gtttctacca
     3181 agccttggaa gaaaactgtg aattctataa taccaatcca cacttcctgc cttttattac
     3241 cagcttgcac cttgtaatgt tggaaaatgg ccgaccaaca aaagaaacac gtagcatcaa
     3301 gatggccttg atgggaccat tggcaggtat tggggattct ctctctcaat tctgtttagc
     3361 tccattgttc tcaaccatcg cagcttcgtt tgctcaagaa ggcttggttg tcggtccaat
     3421 cttgttcttc cttgcgatga atacgatttt aacagcgatt aaattgtcaa ctggtctgta
     3481 tggatacaaa ctaggaacaa ctgtgattga taaactaagc gaacagatgg caacgatttc
     3541 tcgtattgcc aatattatcg gtgtaaccgt aattgctggt ttggcagcga catctgttaa
     3601 gattatggtg ccgattacct ttgctgcagg ggaagttaaa gcagacgcta aacaaagtat
     3661 cgtaagtatt cagggaatgc ttgataaggt tgctccagct cttctaccag ccctatttac
     3721 acttttagtt tactacttga tcaaagaaaa gaaatggaca acatataaac tcgttatttt
     3781 aacagttatc atcggaatta tcggaagctg gcttaagatt atagcttaat ggatacaaca
     3841 ttgttttatg gaatagtgat tgtcttggca gtgagtcccc ttttactgtc aagctttcat
     3901 tctattcgtc agcaaaagtt gcttcgcaaa cagatggagc aacgacaaga gtatttagct
     3961 tctttaacat ctggtgatga agtgttgtta ttgtctggaa ttcatggaaa aatcatttct
     4021 atccaagatg acttggtctc cttgcagatt gcaaaaggtg tggtcatcta tgtagaaaag
     4081 gaaagtgtaa tgggaaagac aaaagaactg ctttttaagt agttcttttt ctggtaatag
     4141 ataatgaaag aagaaagaag acaatttttt gaaagaatcg atggaaacca atgtcgtgat
     4201 tatatcttgt cccactgttc aaaagactat gagaaagtca agagttccct tgaacgcttg
     4261 atggacaatc gttttatgtt tgatagtcct tgggatatgg agccttgttc aaaaatccat
     4321 caaatccagc cgatggtatg ggatcaagta tttgaagatg atccagaatg ggcttatatg
     4381 ctcaatcgac aagaatatct cttgcagttt atgatagggt atctggtaga aggagataag
     4441 gactatattc aaaagtgcaa gttctttcta tttgattgga ttgagcaggt gagagaattt
     4501 tctcctcaat ccttgatgac tagaaccttg gatacgggta ttcgttcctt tacttggttg
     4561 aaactactct tgcttctctt gaaatttgac ttgctagagg agaaagaact agagaaaatt
     4621 ttggtcagtc tagaaaagca gattgacttt atgaaaagct actatcgcgc caagtacacc
     4681 cttagtaact gggggatttt acaaacaatt ccgatgcttg ctatctatca tttcttttca
     4741 gataagatgg acctagaaga agcttaccat tttgcttcag aggagttgaa acagcaaatt
     4801 gagacacaga ttttaggaga tggaagccag tttgaacagt cgattctcta tcatgtagag
     4861 gtttataaag ccttgctgga tttgtgtctc ttgcttccag acttgcaaga tagttaccaa
     4921 gagttgctgg aaaagatggc gacctatatt caaatgatga caggcttaga tggacgaact
     4981 ttggcttttg gtgatagcga ttctacagaa acgacagaaa ttttgagcct gtctgctgtg
     5041 gttttgaaca aggaagacct tcttaacggt ctggatgtta aagtcgattt gcttagcctc
     5101 ttgttcctgg ggcgagaaaa ggtcaagcga ctgcaggaat ttgaaaagag agcttggcag
     5161 cctaggtcca tgatctttga agactctgga catgtctgca ttaaggatga acatcgttat
     5221 ctatttttca aaaatggtcc gctaggaagt gcccatagcc atagtgacga gaatagtttt
     5281 tgcttacagt atcaaggcca acctattttc atagatgctg ggcgttattc ttatcgggag
     5341 atatatgaac gttatctctt aaagagtgct tggagtcatt cgacctgcat tgtagatggg
     5401 aaagctccgg aaagaatcac gggatcctgg gaatatgaat actatcctca ctccctgttt
     5461 tgtcaccata aagaaaggga gggagtgcat tatattgaag gggcttattg gtcagcagaa
     5521 cctgatttgc cttatcttca caagagaaaa atcctcatgt tggtagagga tgtctggctc
     5581 ttggtagatg acatcaggtg tcaaggtcag catgaggcgt tgactcagtt tatccttgac
     5641 aaggatgtga cctatcaaga tgggaaaatc aatcagttga gactatggag tgaagttgat
     5701 tttgatttgg aagataccat catttctcct aaatacaatg agcttgaaag aagtagcaaa
     5761 ctcaccaagc gccaattctt tgagaatcag atgctggatt ataccatcat tgcgcatgag
     5821 agttttgaaa tcatccgtca ttctgtctac cagacagatg atcgtgaagt ggaaaatgct
     5881 ctggcttttg aagtgaaaaa tgacgaaaca gacaagctga ttctgttatt aagcgaggat
     5941 attggtgtag gtgaaaaatt gtgcctcgtt gacggaacaa aaatgcgtgg aaaatgtcta
     6001 gtatatgata aaataaatga gagaatgatt cgcttgcagt gctagaaata ggcattttga
     6061 atagtgaaca tgttataata agtattagta ggaggtgttt tagattggag aagaaactga
     6121 ccataaaaga cattgcggaa atggctcaga cctcgaaaac aaccgtgtca ttttacctaa
     6181 acgggaaata tgaaaaaatg tcccaagaga cacgtgaaaa gattgaaaaa gttattcatg
     6241 aaacaaatta caaaccgagc attgttgcgc gtagcttaaa ctccaaacga acaaaattaa
     6301 tcggtgtttt gatcggtgat attaccaaca gtttctcaaa ccaaattgtt aagggaattg
     6361 aggatatcgc cagccagaat ggctaccagg taatgatagg aaatagtaat tacagccaag
     6421 agagtgagga ccggtatatt gaaagcatgc ttctcttggg agtagacggc tttattattc
     6481 agccgacctc taatttccga aaatattctc gtatcatcga tgagaaaaag aagaaaatgg
     6541 tcttttttga tagtcagctc tatgaacacc ggactagctg ggttaaaacc aataactatg
     6601 atgccgttta tgacatgacc cagtcctgta tcgaaaaagg ttatgaacat tttctcttga
     6661 ttacagcgga tacgagtcgt ttgagtactc ggattgagcg ggcaagtggt tttgtggatg
     6721 ctttaacaga tgctaatatg cgtcacgcca gtctaaccat tgaagataag catacgaatt
     6781 tggaacaaat taaggaattt ttacaaaaag aaatcgatcc cgatgaaaaa actctggtat
     6841 ttatccctaa ctgttgggcc ctacctctag tctttaccgt tatcaaaaag ttgaattata
     6901 acttgccaca agttgggttg attggttttg acaatacgga gtggacttgc ttttcttctc
     6961 caagtgtttc gacgctggtt cagccctcct ttgaggaagg acaacaggct acaaagattt
     7021 tgattgacca gattgaaggc cgcaatcaag aagaaaggca acaagtcttg gattgtagtg
     7081 tgaattggaa agagtcgact ttctaaaatg aaggaaaatg acttgcaatc tctgttaaga
     7141 aataaaataa tcccacctag aacaagctag gtgggattat ttgcctatga aatgagaaat
     7201 tatgggagca agctcctaaa tcaactgttt ttgatctact tctttaacta cttgataaaa
     7261 gttatagaag taggccaaac ttgaaatgat ggttacgact aggaatattg aaaatttcca
     7321 ttggacaggg ttggttaaaa gttgtggaaa ggatatgagg agaaagaaga gggctgcgtt
     7381 gaggacaggt atccgttttg attgtatttt ctcaagtcct ttattgagcg caggaagaaa
     7441 gaggagtagg agtagtaaaa ctgtatgaga aacagctcct gaaataaggg caaagaaaag
     7501 gaaaatactg ataaaaacat gaatgatcag tagtctagct agtgatttca taaggtacct
     7561 cctaatcctg gtctttttta gctcttgcaa tacgaagtga gtcgacaata tgtatcatca
     7621 ctccgaaaaa gaaagctccc agtatagttt taaaaatatg ttttgtattt agaagagaac
     7681 tgataaaatt tggattttca cttgttaggg tatcaatgag tggaattata aaaaatatca
     7741 ctgttccata aatcgaacct gctttcagac caggataacg taactgtttc ttttcttttt
     7801 tcatgagttt gctccttttt taaaaatctt cctcccaaaa gagactgttg aggtcagttt
     7861 ggaggctgcg ggcgagattg agacagagtt ccaaggttgg attgtacttg tcgttttcaa
     7921 tcatattgat agtctgtctc gagacaccga tattcttggc gagctcgagc tgggaaatgc
     7981 ccagttcctt gcgaaattct ttcacacgat tcatctgttc ttctttctga tttatgtcgt
     8041 atatatttga ctatattata gtcttttaaa cataaagtgt caagtatttt tgacatattt
     8101 tttgaagaaa tagtagtctc cttgtcctat ttgtctgaca agtgcaagct ggtcggattt
     8161 gtggtaaaat agataagata tgacaaaaga atttcatcat gtaacggtct tactccacga
     8221 aacgattgat atgcttgacg taaaacctga cggtatctac gttgatgcga ctttgggtgg
     8281 agcaggccat agcgagtatt tattaagtaa attaagtgaa aaaggccatc tctatgcctt
     8341 tgaccaggat cagaatgcca ttgacaatgc gcaaaaacgc ttggcacctt acattgagaa
     8401 gggaatggtg acctttatca aggataactt ccgtcattta caggcacgtt tgcgcgaagc
     8461 tggtgttcag gaaattgatg gaatttgtta tgacttggga gtgtctagtc ctcaattaga
     8521 ccagcgtgag cgtggttttt cttataaaaa ggatgcgcca ctggacatgc ggatgaatca
     8581 ggatgctagt ctgacagcgt atgaagtggt gaacaattat gactatcatg acttggttcg
     8641 tattttcttc aagtatggag aggacaaatt ctctaaacag attgcgcgta agattgagaa
     8701 agcgcgtgaa gtgaagccga ttgagacaac gactgagtta gcagagatta tcaagttggt
     8761 caaacctgcc aaggaactca agaagaaggg tcatcctgct aagcagattt tccaggctat
     8821 tcgaattgaa gtcaatgatg aactgggggc ggcagatgag tccatccagc aggctatgga
     8881 tatgttggct ctggatggta gaatttcagt gattaccttt cattccttag aagaccgctt
     8941 gactaagcaa ttgttcaagg aagcttcaac agttgaagtt ccaaaaggct tgcctttcat
     9001 cccagatgat cgcaagccca agatggaatt ggtgtcccgt aagccaatct tgccaagtgc
     9061 ggaagagtta gaagccaata accgctcgca ctcagccaag ttgcgcgtgg tcagaaaaat
     9121 tcacaagtaa gagggaaaaa gatggcagaa aaaatggaaa aaacaggtca aatactacag
     9181 atgcaactta aacggttttc gcgtgtggaa aaagcttttt acttttccat tgctgtaacc
     9241 actcttattg tagccattag tattattttt atgcagacca agctcttgca agtgcagaat
     9301 gatttgacaa aaatcaatgc gcagatagag gaaaagaaga ccgaattgga cgatgccaag
     9361 caagaggtca atgaactatt acgtgcagaa cgtttgaaag aaattgccaa ttcacacgat
     9421 ttgcaattaa acaatgaaaa tattagaata gcggagtaag atatgaagtg gacaaaaaga
     9481 gtaatccgtt atgcgaccaa aaatcggaaa tcgccggctg aaaacagacg cagagttgga
     9541 aaaagtctga gtttattatc tgtctttgtt tttgccattt ttttagtcaa ttttgcggtc
     9601 attattggga caggcactcg ctttggaaca gatttagcga aggaagctaa gaaggttcat
     9661 caaaccaccc gtacagttcc tgccaaacgt gggactattt atgaccgaaa tggagtcccg
     9721 attgctgagg atgcaacctc ctataatgtc tatgcggtca ttgatgagaa ctataagtca
     9781 gcaacgggta agattcttta cgtagaaaaa acacaattta acaaggttgc agaggtcttt
     9841 cataagtatc tggacatgga agaatcctat gtaagagagc aactctcgca acctaatctc
     9901 aagcaagttt cctttggagc aaagggaaat gggattacct atgccaatat gatgtctatc
     9961 aaaaaagaat tggaagctgc agaggtcaag gggattgatt ttacaaccag tcccaatcgt
    10021 agttacccaa acggacaatt tgcttctagt tttatcggcc tagctcagct ccatgaaaat
    10081 gaagatggaa gcaagagctt gctgggaacc tctggaatgg agagttcctt gaacagtatt
    10141 cttgcaggga cagacggcat tattacctat gaaaaggatc gtctgggtaa tattgtaccc
    10201 ggaacagaac aagtttccca acgaacgatg gacggtaagg atgtttatac aaccatttcc
    10261 agccccctcc agtcctttat ggaaacccag atggatgctt ttcaagagaa ggcaaaagga
    10321 aagtacatga cagcgacttt ggtcagtgct aaaacagggg aaattctggc aacaacgcaa
    10381 cgaccgacct ttgatgcaga tacaaaagaa ggcattacag aggactttgt ttggcgtgat
    10441 atcctttacc aaagtaacta tgagccaggt tccactatga aagtgatgat gttggctgct
    10501 gctattgata ataatacctt tccaggagga gaagtcttta atagtagtga gttaaaaatt
    10561 gcagatgcca cgattcgaga ttgggacgtt aatgaaggat tgactggtgg cagaatgatg
    10621 actttttctc aaggttttgc acactcaagt aacgttggga tgaccctcct tgagcaaaag
    10681 atgggagatg ctacctggct tgattatctt aatcgtttta aatttggtgt tccgacccgt
    10741 ttcggtttga cggatgagta tgctggtcag cttcctgcgg ataatattgt caacattgcg
    10801 caaagctcat ttggacaagg gatttcagtg acccagacgc aaatgattcg tgcctttaca
    10861 gctattgcta atgacggtgt catgctggag cctaaattta ttagtgccat ttatgatcca
    10921 aatgatcaaa ctgctcggaa atctcaaaaa gaaattgtgg gaaatcctgt ttctaaagat
    10981 gcagctagtc taactcggac taacatggtt ttggtaggga cggatccggt ttatggaacc
    11041 atgtataacc acagcacagg caagccaact gtaactgttc ctgggcaaaa tgtagccctc
    11101 aagtctggta cggctcagat tgctgacgag aaaaatggtg gttatctagt cgggttaacc
    11161 gactatattt tctcggctgt atcgatgagt ccggctgaaa atcctgattt tatcttgtat
    11221 gtgacggtcc aacaacctga acattattca ggtattcagt tgggagaatt tgccaatcct
    11281 atcttggagc gggcttcagc tatgaaagac tctctcaatc ttcaaacaac agctaaagct
    11341 ttggagcaag taagtcaaca aagtccttat cctatgccta gtgtcaagga tatttcacct
    11401 ggtgatttag cagaagaatt gcgtcgcaat cttgtacaac ccatcgttgt gggaacagga
    11461 acgaagatta aaaacagttc tgctgaagaa gggaagaatc ttgccccgaa tcagcaagtc
    11521 cttatcttat ctgataaagt agaggaagtt ccagatatgt atggttggac aaaggagact
    11581 gctgagaccc ttgctaagtg gctcaatata gaacttgaat ttcaaggttc gggctctact
    11641 gtgcagaagc aagatgttcg tgctaacaca gctattaagg acattaaaaa aattacatta
    11701 actttaggag actaatatgt ttatttccat cagtgctgga attgtgacat ttttactaac
    11761 tttagtagga attccggcct ttatccaatt ttatagaaag gcgcaaatta caggccagca
    11821 gatgcatgag gatgtcaaac agcatcaggc aaaagctggg actcctacaa tgggaggttt
    11881 ggttttcttg attacttctg ttttggttgc tttctttttc gccctattta gtagccaatt
    11941 cagcaataat atgggaatga ttttgttcat cttggtcttg tatggcttgg tcggattttt
    12001 agatgacttt ctcaaggtct ttcgtaaaat caatgagggg cttaatccta agcaaaaatt
    12061 agctcttcag cttctaggtg gagttatctt ctatcttttc tatgagcgcg gtggcgatat
    12121 gctttctgtc tttggttatc aagtgcatct agggattttc tatattgtct tcgctctttt
    12181 ctggctagtc ggtttttcaa acgcagtaaa cttgacagac ggtgttgacg gtttagctag
    12241 tatttccgtt gtgattagtt tgtctgccta tggagttatt gcctatgtgc aaggtcagat
    12301 ggatattctt ctagtgattc ttgccatgat tggtggtttg ctcagttttt tcatctttaa
    12361 ccataagcct gctaaggtct ttatgggtga tgtgggaagt ttggccctag gtgggatgct
    12421 ggcagctatc tctatggctc tccaccaaga atggactctc ttgattatcg gaattgtata
    12481 tgtttttgaa acaacttctg ttatgatgca agtcagttat ttcaaactga caggtggtaa
    12541 acgtattttc cgtatgacgc ctgtacatca ccattttgag cttgggggat tgtctggtaa
    12601 aggaaatcct tggagcgagt ggaaggttga cttcttcttt tggggagttg ggcttctagc
    12661 aagtctcctg acccttgcaa ttttatattt gatgtaagaa tggcaccctg atgtttcagg
    12721 gtgtttttgt gtttaaatac acaatgaaaa tcaaagaaca aactagaaag ctaactttag
    12781 gctgctcaaa atatagtaga tt
//
LOCUS       DBEJKC010000054        12635 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.054, whole genome shotgun sequence.
ACCESSION   DBEJKC010000054 DBEJKC010000000
VERSION     DBEJKC010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12635
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.054"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(94..930)
                     /locus_tag="ACL3G6_001668"
     CDS             complement(94..930)
                     /locus_tag="ACL3G6_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0546158.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(943..1572)
                     /locus_tag="ACL3G6_001669"
     CDS             complement(943..1572)
                     /locus_tag="ACL3G6_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0546159.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASELLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(1582..2223)
                     /locus_tag="ACL3G6_001670"
     CDS             complement(1582..2223)
                     /locus_tag="ACL3G6_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0546160.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGVVTIISKKVEKKYSYYR"
     gene            complement(2369..3598)
                     /locus_tag="ACL3G6_001671"
     CDS             complement(2369..3598)
                     /locus_tag="ACL3G6_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGR0546161.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(3588..4754)
                     /locus_tag="ACL3G6_001672"
     CDS             complement(3588..4754)
                     /locus_tag="ACL3G6_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGR0546162.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            4898..5911
                     /locus_tag="ACL3G6_001673"
     CDS             4898..5911
                     /locus_tag="ACL3G6_001673"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HGR0546163.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(5956..6375)
                     /locus_tag="ACL3G6_001674"
     CDS             complement(5956..6375)
                     /locus_tag="ACL3G6_001674"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HGR0546164.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(6386..7792)
                     /gene="atpD"
                     /locus_tag="ACL3G6_001675"
     CDS             complement(6386..7792)
                     /gene="atpD"
                     /locus_tag="ACL3G6_001675"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HGR0546165.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(7878..8756)
                     /locus_tag="ACL3G6_001676"
     CDS             complement(7878..8756)
                     /locus_tag="ACL3G6_001676"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HGR0546166.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(8772..10277)
                     /gene="atpA"
                     /locus_tag="ACL3G6_001677"
     CDS             complement(8772..10277)
                     /gene="atpA"
                     /locus_tag="ACL3G6_001677"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HGR0546167.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(10292..10828)
                     /locus_tag="ACL3G6_001678"
     CDS             complement(10292..10828)
                     /locus_tag="ACL3G6_001678"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HGR0546168.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(10828..11322)
                     /gene="atpF"
                     /locus_tag="ACL3G6_001679"
     CDS             complement(10828..11322)
                     /gene="atpF"
                     /locus_tag="ACL3G6_001679"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HGR0546169.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(11336..12052)
                     /gene="atpB"
                     /locus_tag="ACL3G6_001680"
     CDS             complement(11336..12052)
                     /gene="atpB"
                     /locus_tag="ACL3G6_001680"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HGR0546170.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQTIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(12087..12287)
                     /locus_tag="ACL3G6_001681"
     CDS             complement(12087..12287)
                     /locus_tag="ACL3G6_001681"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HGR0546171.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(12362..>12635)
                     /locus_tag="ACL3G6_001682"
     CDS             complement(12362..>12635)
                     /locus_tag="ACL3G6_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0546172.1"
                     /translation="NVFSEEHIYYAHPYASWERGTNENHNRLIRRWLPKGTKKMTPKE
                     VAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRFQ"
BASE COUNT         3854 a         2816 c         2264 g         3701 t
ORIGIN      
        1 aattatccag attcaatcgc tattatcgtt ttcctagatt acaaaaaaac tacgttttgc
       61 taatcaaaac gcagtttcag ccactatttt atcttactgt ccttctttta cttctttggt
      121 tgctacatct tctccaaacc atttttggct gatttcttgg aacttgccgt ccttgtaaag
      181 actagaaaaa gcttcattta tcttcttaac caaggttgta tcttccttac gggctccaac
      241 cgcaaaagct tctgtttcta gtccaactgt aaagacatta taatcgttta aaacaccttc
      301 tgcttctaaa taatagtttg catagacacg gtcaatcaat agaccatcaa ttcgatcgtt
      361 tttcaaatca atcaaggctt cattaaaggt ttggtattga ttcgcttcct tattagcgac
      421 aatattcttc aaaagttctg gatttgcttc aaagtccgca taaccagatg aaccagcttg
      481 agctcctaat gtctttccag tcatatcctt tgcagtcgtg ataccagatg atttcttcgt
      541 aaccaatacc tgctcattct tcatatatga gttactgaaa gccacctttt cacggcgttc
      601 gtctgtagcg gaatagccat tccaaatcag atcaatcgtt ccttttgtca attcagcttc
      661 tttcaaatcc caatcaatcg gttgccaatt taccgtgatt ccgtattttt caaaaacagc
      721 tgtagctaaa tcaatatcaa atcctgcata agaaccatct ttctgagcaa atcccattgg
      781 aacaaaagta ctatcaaatc caatagtaat agacttgtta gactggtact ttgaccaatt
      841 atctccacta gtttcgctag aatttttccc acaagctact aagaacaaag cagtcatcag
      901 actgactaat acaagcatcc attttttcat ccatttttcc tcctatttag gttctacttt
      961 caataataca tctgcgatat tttcagcaaa ctgcaaatca tgggtaacca caatctgggt
     1021 catcccaagt tccctatttt gcaagattag cttctccact tccaaacgta attctggatc
     1081 cagggcagaa gttggttcat cgtagccaat gatttctggg tcaatcatca tagcacgcgc
     1141 caaagccacc cgctgctttt gcccaccaga tagtgagaaa ggataggcct ctgcgtgtcc
     1201 tcctagtcct aactgttcca agagttcact cgccttcttc tcagcctctt cctgcttcat
     1261 tcccatggtc ttcacaggcg ataaagtcaa attttccaga actgatagat gaggaaatag
     1321 ttgaaaatct tggaagacaa atcccagtag gttgcgcttc tgcaattcat ctagctctaa
     1381 aggttgtcca ttataaaaga tttgccctga atcaatggtt tcaagacctg caagcatacg
     1441 taaaagagtt gtcttacctc caccagaagg tccaacgata gccaggattt gcttttcagg
     1501 aatacttaga ctgaaatcag acaggatttg tttgtctcca aagactttat tgatatttcg
     1561 taattctaac atagctgccc cctatctata ataactatac ttcttctcaa cttttttgga
     1621 aataattgtc acaaccccaa ttaaaatcaa gtaaatggct cctgccaaga acataggaac
     1681 cagactagca tcgcggttag cagctgttcg actagccaag ataaggtctg aaattccgag
     1741 agcatagacc aaagaagtat ccttgaccaa actcataact tcattaaaga cactaggaag
     1801 aacgatcttg gtcacttggg gcaagataat atagcgcact ctgtcaaaag ggctaaactt
     1861 caagaccttg gcagcctcat actgtcctct tggaatagtg tcaattcccc cacggaaaat
     1921 ttctgcaaag taagctgcat agttgagaac aaaggcaata atagctgcag gaaggcggtc
     1981 taaacgaatc ccaatacttg ggagcacata atagataaaa atcagttgca agagtaaggg
     2041 ggttcctcgc ataacccaga tgtaaatgtt aatcagataa tggaggggct tccaatggac
     2101 ttgcaaggca aaggcaatca aaacgcccaa cggaatcgaa aatagcaaga ccagtgcaaa
     2161 gacctgtaca gtcgtgctcg caccattcag taaactcggt aatatctcaa ataaataaga
     2221 catactgcac ctcctaaaag taattgttcc tattatagca tgaataaaca agattaccaa
     2281 gtatttttgt aaaaagattc taccatatac aaataaaaac cgcagctatc aaaagagata
     2341 aactacagtt ctatatgttt aaacattctt acaatctctc aaacagttct tgcatttgca
     2401 catcatctgg aaccagtttt aagtaagtgt gagcatggac ttttgcttct tcaaaatgtc
     2461 ccaattcacg caagagatag atatagtgtt ccagaaattc tggattgtcc ttcaaatctc
     2521 ctgtcaactc ttgataatgc tcataagcag tatccaaatc gtccatttct tgataagaac
     2581 gagcaatcat ccacttggtc aaaagatttt ctggctcctc actctgcaag tctagaatat
     2641 cctcataacg ctcctgctcc agataaatag tggctaaacg aagcaagatt tcttctgtat
     2701 cctcagcgtc ttcttttgca gtaaggagat aattttctgc accactagca tcatgcaatt
     2761 cataagaaaa ttgtgaagca gctagcaaga ggcgagtttc aaagggattt ttctctaatc
     2821 cttgcttagc gatacgcagg gcttcttgaa cttgatgttc cttatgtaaa gcctgactgt
     2881 acccatactc atagccttca aagtcaggag aaatggtatc aagctgctta aagtagaggg
     2941 tggctttttg atattcttct tgatcaaaat aaagactggc caactcaaaa gctgttaagt
     3001 catcgtattc taactccagg gctttttcta aaaactcagt agccgtttca aatttcccta
     3061 actgagcata ggcaaagcca attcgttgat aggtggaaat gcccgtttgc tcataaatcg
     3121 agcgattatc taactgggca taggcttgaa tagccgcttg gtaattttcc aactcactat
     3181 ccaactctgc caaacccaat atcaagagag aatcctctga gtaggtcaag gcctccaata
     3241 atttctcacg tgccacatct gtcaaacctt ccagctggta aaggtctgcc ttcaaaacca
     3301 aagacgagac ataccagtca ctgtcagctt ggatttcctc aagataggta aaggcttctt
     3361 ctatttgacc atcctcgcta gcaattgcag ctagattaag atgaacctct ggaaaatcct
     3421 ctacaatttt caggtaaatt tccttggcct gaggatagaa accaatccct tcaagataag
     3481 ttgccaactc atacagaaga tcacttgaat cattttctaa agctttggcg aaataatgct
     3541 cagccttagt taaatcttgc tcctccaaag cctgtaacat ctgttgacta ttgttcactc
     3601 ttgacttcct caccctctaa ttcatataga ccactgacta ccttatacca ttcgaaaatg
     3661 gctgaaatga caaccttagc agaggcataa actggaatac caagtaaaac tccccagata
     3721 ccaaacatag atcctgaagt taacaaaaca aagagaacat taatagggtg gatgtttaat
     3781 tgacttccca aaatcaatgg agagacaaaa cggccttcaa tagtttgttc tacaataaag
     3841 acaatcacta ctttcaaaag catgactgga ccagcaatca aacccaatac tagggcagga
     3901 agcatggcta gaaagctacc aagataaggg accagattta aaataccagc agtaaccccc
     3961 agcgtaaccg catagcgtag accaataatc ttgaagaaga tgataaacat tactgctaca
     4021 ataatagcca ctgtcacttg ccctcgaaca tagttggaca actgttgatt cacatctgat
     4081 agaacttgtc caacaggttc cttcaatttt cttggaatga attgggtcaa atagttacgc
     4141 aagcctttcc catcacgcaa gagataaaag agcatgaaag gaacgataat caaggcaaca
     4201 atcacttgag aagccccgct aataaaggca ctcacccagt tgactgcctg agatgaaacc
     4261 ttacttgcca aaactgtagc ctggctagaa aaattggtca aaacttgctc taattgaggt
     4321 ctgaaatcat ctggcagatg ctgggctacc aatccattaa caatcctatc tatatcttct
     4381 aagtaaacag gaacgtttct tgcaaaggtc aaaacctgac gttgcagatt tggaatggcg
     4441 actgccaagc cccaaatgat aaagagagcg atgataacaa agacaatagt gatagctata
     4501 acacgattaa ccttatgctt ctccatccaa tcaacaatag gattcaacaa ataatataac
     4561 aaaccagaca aaatgactgg caacatcaca actgctaaaa agtctaaaac aggtgaaaat
     4621 agaaaactaa tcttacttaa aataaaaaga ttcaatccca ataataaggt tactaaaaat
     4681 accgtaattg ccttgttatc taaaaaccac ttgaaaaacc aagataggct aaaatgtttc
     4741 tctttttgct ccataaatac ttcctttcta ttgttctctc attataccat ttttgaaaca
     4801 aaataactct tttttaaagt gcttacatct aattgaatgt ctttaatttg cttgtttttg
     4861 tgatataata gtcttatctt tacacagagg tatagtaatg aaagaaactg tttattttgg
     4921 aacttataca cgtcgtactt ctcaagggat ttacaaggca gactttgata cagaaactgg
     4981 tcagctttca aatctagaac tttttgcagc tgagccaagt ccaacctacc ttgcctttga
     5041 ccagcaccaa catttataca ctgttggtag ccaagacgat aaggggggaa ttgcagccta
     5101 tcaaactgac gggactgtgt taaatcatgt tgttgaagaa ggagctcccc actgttatgt
     5161 tgctgtcgat gaaaagcgtg atttggttta cgcagccaac tatcacaagg gacaagtcct
     5221 tgtttataaa cgccaggaag atggtagtct tctacttagt gatatggatc aacacagtgg
     5281 ccaaggtcca catgaaaatc aagcttcccc ccatgttcac tatacagatt taacacctga
     5341 ccactatcta gtgacctgcg acttgggaac tgaccaagtc atcacctatg acctcgatca
     5401 agaaggaaaa ttatctaagc tctataccta tcacagcaag ccaggagcag gctcacgcca
     5461 tatcattttc cataaccact ataaaatcgc ttatctcatt tgtgaactca atagtactat
     5521 cgaagtttta atctacgatg gcgttggcga atttgaacgt atgcaggtca tttcaacttt
     5581 accggaagct tacgaaggct ttaatggaac cgctgctatt catctctcta aagacggtaa
     5641 atacctctac gcttctaacc gtggccatga ttctatcgca gtatatacca tccttgcgga
     5701 cggtagctta gagttattag aaatcgttcc aacgcatggt cagactccac gtgattttga
     5761 tttgacaccc gaccaaaaat ttctcattgt tgtccatcaa gactctgaca atgcaactgt
     5821 ctttaaacgt aattgtgaca atggtcgtct agcagaactc tccaacgact tccatgttcc
     5881 cgaagcagtc tgcatccgtt ttgctcctta aaacaccata aaaaatgaac ttggtatttt
     5941 caagttcatt ttttcttata gtctatttcc gacattaata cggttaatag cacgttgcaa
     6001 agcaatctta gcacgacgtt cttggtcaat caaatgtttg tcttgtgctt cttcaattgc
     6061 acgttctgca cgaagtttgg cacgttctgc acgactgata tcgatatcac gagcacgttc
     6121 tgcagagtca gcgacgattg tgatcatatc attggcaatt tcaataacac caccgtttac
     6181 tgcaatccag ttcacgtgat ctttatcatc gatacgtttt acctttactt catcaactgc
     6241 taaaactgca atcatatttt catgtcgtgg caagatcccc atctcaccat ccagagttcg
     6301 aaccgataca tagctggcat ggtgatcata gacgagacca tctggtgtca cgatctggac
     6361 agttaactga gccatagatc acctcttaaa atcccatttt ttcagctttt gcaatcacat
     6421 cttcgataga acctacacca cggaaggcat cttctggcaa gtggtcgtat ttaccatcaa
     6481 ggatttcctt aaagccacgt acagtttcag caactggaac ataagaacct ggctgaccag
     6541 taaattgttc cgcaacgttg aagttttgtg acaagaagaa ctggatacga cgggcgcgag
     6601 caaccaaggt cttttcttca tcagaaagct catccatacc aaggatagca atgatatctt
     6661 gcaattcatg gtaacgttga aggacacgtt ttacttcagc agcaactgca tagtgctctt
     6721 ctccaacgat ttcaggtgcc aaggcacgtg agcttgaagc aagtgggtca acggctgggt
     6781 agatacccaa ttgtaccaac ttacgttcca agtttgttgt tgaatccaag tgagcgaagg
     6841 ctgttgctgg cgctgggtca gtatagtcat ccgctggcac atagatagcc tggatagagg
     6901 ttacagaacc cttcttggtt gatgtgatac gttcttgcaa ttgacccatt tccgtagcaa
     6961 gtgttggttg gtaaccaacg gctgatggca tacgacccaa aagggcagat acttctgaac
     7021 cagcctgagt gaaacggaag atattatcga taaagagaag cacgtcttgg ccttccacat
     7081 cacggaagta ttcagcgatt gtcaaaccag taagggcaac acgcatacgt gctcctggtg
     7141 gctcattcat ctgaccaaag accatggctg ttttctcgat aacgcctgat tctttcattt
     7201 cccagtaaag gtcattcccc tcacgagtac gttccccaac accagcaaat actgaaatac
     7261 caccgtgctc ttgggcaatg ttgtgaatca attcttggat taagacggtt ttaccaactc
     7321 cggcaccacc gaaaagtcca actttaccac ctttaaggta aggggcaaga aggtcaataa
     7381 ccttgatccc tgtttcaagg atttcagaag aggtagacaa ctcatcaaaa gttggagctt
     7441 ttttatgaat tggctgacgc tctgcgtctt ctgtaaaagg agcttccaaa tcaatggtat
     7501 ctcccaaaac gttgaagaca cgtcccaaag tttctttacc tactggtaca gagattggac
     7561 gacctgtgtc caatacttcc attccacgag tcaacccatc tgttgattcc atggcgatag
     7621 tacgaaccat accatctcct aactccaagg ctacttcaag gacgattttt gtttttcttt
     7681 cgtcattttt gtagacgaca agtgcattgt taatctcagg aagtttttcc cctgctgcaa
     7741 acaaaacgtc tacaacggga ccgataacct gagcaatttt acctgaactc atctccttct
     7801 cctattctat ataagatact gtcggttcct agctcaacta ggtcctaagt tcattttcat
     7861 acgagctgga ctagggccta ttctaaggca ctagcacctg ctacgatttc tgtaatttct
     7921 tgtgtaatcg ccgcctgtct ggcacggtta tactgaattg tcaaatcatt gatgactttc
     7981 ttagcattat ctgtcgctgt ttgcatggct gtcatacccg cagcattctc agctgtcttg
     8041 gcatcgataa tggcaccgta aatcatactt tctgcaaact gaggcaacaa ctgctccaga
     8101 atttcttctc ggctggtttc caattcaaaa gtcaagctgt actcttcatc cgcttcattt
     8161 ggatccaagt caacaatcgg aagcatttgt tccacacgca tttgactggt tagcgtattg
     8221 acatggtggt tgtagcaaac ataaagctca tcaaagagtt cattttggta catttcaaca
     8281 gtttttgaaa taatcttacg aacttgatca aagctaggtt ggtctgccaa gccacgtaat
     8341 tcataaagtg gttgaatacc gcgagcctta aagaaatcag ctcccatccc accgatacag
     8401 atcatttcaa aacctttacc gtctgggtgg tattcttctt tcaactccat aacagctttc
     8461 aaaatagagg aattataacc tccaaccaaa ccgcggtctg aagtgataac gatatagcct
     8521 gtcttcttca cagaacggct aatcaacatc ggattagttg aagcaccagc tccattacca
     8581 tgaaggatat ctgtcaaaag tttacgcact ttctgagcgt aaacttggaa gttgcgagca
     8641 gcttcttcag agcgacctaa cttagcagcc gataccattt gcatggcatt agtgatttga
     8701 ctcgtatttt ttgttgaggc gatttttgtt ttaatatcat ttagagacac tgccatctga
     8761 cacctctatt cttattggaa gctagattga ttgagaaact ctgtaatcgc agcatccaag
     8821 actgcttctt ctggcaagtc ttttgtatca cgaatggttt ccaaaatctc tggatgttga
     8881 gcatcaaaga aggcatggaa ctcttcctcg aaacgaacaa tatcatctac tggaacagta
     8941 tccaagaaac catgtgtcaa agcataaaga atggttactt gtttctcaac aggtaatggt
     9001 ttgtgaacag gttgtttcaa gacctcaacg gtacgacgtc cacggttcaa cttagcctgt
     9061 gttgctgcgt ccaagtcaga accaaactta gtaaaggctt ccaactcacg gtatgaagca
     9121 aggtcgatac gaagtgtacc agcaaccttc ttcatggctt tgatttgtgc agaaccacct
     9181 acacgagata cagatgaacc cgcatcgatg gctggacgaa tacctgcatt gaagaggcca
     9241 tcgccaagga agatttgtcc atcagtgata gaaatcacgt tggttgcgat ataggctgag
     9301 atatctcctg cttgtgtctc gataaatggt agggctgtaa ttgatccacc accaagttca
     9361 tcagaaactt tagctgagcg ctcaagcaaa cggctgtgga gatagaaaac atcccctggg
     9421 aaggcttcac gacctggagg acgacgaagc aagagcgata gttcacgata agctaccgct
     9481 tgttttgata gatcatcgta tacaatcaaa acatgcttac cttgatacat aaattcttcc
     9541 gccatagcaa ccccagtata aggagctagg aagagcaatg gagatggttg tgaagcagag
     9601 gctgtcacaa cgattgtgta gtccaaggca ccgtactgac gaagtgtttc tacttgcgta
     9661 cgaactgttg attctttttg tccaatcgcg acgtagatac agatcatatc ttgatctttt
     9721 tggttcaaga ttgtatcaat cgcaatggtt gttttccctg tctgacggtc accgataatc
     9781 aactcacgtt gaccacgacc aatcggtaca agggcgtcaa tagctttcaa accagtttgc
     9841 aatggttctg aaacagactt acgttgcata acaccaggag ctggtgcttc tactggacga
     9901 gttttatcag tgtggatttc tccaagaccg tcaactggac gaccaagcgg atccacaaca
     9961 cgaccaatca gactttcacc tacagggact tccatgattt tccctgtacg gcggattgta
    10021 tcgccttcac ggatatctgt aaagtcacct aggatgataa taccaacgtc tgttgactcc
    10081 aagttttgag ccataccata agagccgttt tcaaaattca acaactctcc actcatgaca
    10141 ttttcaaggc catgagcacg cgcgataccg tccccgatat aggttacaac acctgtttca
    10201 gtcacatcaa aattgggttt gaaattttca atttgttgct taattaaagc gctgatttct
    10261 tgtgcgttaa ttgccaaaag aacaccactt tctatttcaa attttcttta acaactttaa
    10321 gttgttgttt aatactcaca tcaattgtct tgtgattggc aaaaatgaca aaaccaccaa
    10381 tgagactttc atcgatttgt tcttttacac tccttacttt cagagacatt tttttctcaa
    10441 tcaaagggag caaacgagtc ttctgttcat cagttagagg atgagcagac gtaatcgtca
    10501 cttcaaatcg atttgtttct ttttcaagtc ggttcaagca atctacaagc acatcataaa
    10561 aaagatttgc tctgtgattg taggccagaa cctggataaa gttttgtaat aaaggcgaca
    10621 cagaatcttg gaaaaaagca attgtttttt ccttatccga ctcgtctact gccacttgtt
    10681 ttaaaaaaga aggcagacct gttttttcaa caacttgctt gatttgagtc aagtctgaaa
    10741 agatacggtc ttcttctcct ttttcaagta ccaattggac aaaaggcatg ctgtattttt
    10801 caattacctt tactgttttc ttgtccatta agcttctcct agctgatcga tatactgatc
    10861 aatgagtgct ttatgggcat gactgtcaag gttttgtgag atgattttac cagctaagct
    10921 gatggtcaaa tctgcgacct cacccttaac actctgtaaa gcttctactt tattttgagc
    10981 aatttcttga ttggcttttt cttttaagtg tcctgcttct agtttagcat ctgctaagat
    11041 attagcctta ctttgctcag ctgtttcctt tgcattttca atgattgtct tagcttcttt
    11101 acggctacca gccaattcat cttcgcgttt ttgagccaat acttctgctt tttgacgggc
    11161 ttcttcagct ctgtcaatat ctgaagcaat tttttcagct ctttcttcga aaatgcctgt
    11221 aatattagac catgcaaatt ttttaatcaa gactagcaaa agaataaaag agccagtgat
    11281 taaaataaaa ttaccaatta attcacctac tgttacgtgc atcagttact cctttctatt
    11341 cctcttcaat attaatctta ttccctaaat acacagatgt caaaagagta aaaacataag
    11401 cttggatgca ggaaataaag acagaaaatg cagtccaagc caaattagct ccaaaggcta
    11461 ctggatacca ataaatagtt tggtgggaaa gaagaagtaa caaactcgtc atgacctctc
    11521 ctgcaaagat attcccaaaa atccgcaaag ccaaagataa gaagtttgta aattcttcca
    11581 agatattcat cggtatgaca aaaacaggac tcataaaaga ttttatactt tttttaaatc
    11641 cacgacgacg aacgctttct atatgtgtca acaaaatgac aagaaaagat aaggttaagt
    11701 catactgtaa attagcggtt ggcgaactcc accagttagt cccatcgatc gtttgaagct
    11761 ttgtcattaa gccaaggtta ttggcaatca ccatgaaaag gaataaacaa aggaaaaaga
    11821 gtgagtaatc tttcatgtag cgcgaaccaa tgttaggttc tgtaaatcca ataacaaagt
    11881 catagacata ctcaagtaca ttttgctttc ctttgggttt caaggtcata ttgcggcttg
    11941 cccaataaat aaagacaaaa ataactccca caatcaacaa agtcatggct aacatagtca
    12001 gattgaagat aacaggacca atagagatga ttggattaat actttcttcc atctaaaatc
    12061 ctcccttttc ttctcgttcc atgtatttat ttgataataa atgagaagac aagagttaca
    12121 aagaaagttc cttcaataaa ggcaacacct aaaaacatca aactacgaaa ctcagaaagc
    12181 atatctggtt ggcgtgctac tgatttaaac agtccattca tcaataaacc ttcaccgaca
    12241 gatacgccca tacaggcaat acataagcct aaaaatgtta aattcataac aaattctcct
    12301 ttaaaataaa atttacttac ttagtgtagt cctaaaattt aaatttgtca acttttaacc
    12361 gctattggaa gcgtttaata aaaattattt ccattttgct aaatttcaag ttcaagttag
    12421 ccatccagaa gtcttctctg ggtgacttgt agtccaagca ttttttagga tagttgttaa
    12481 tccacttttc gatgaatgcg acttctttgg gagtcatttt cttggttccc ttaggtaacc
    12541 atctacgaat gagcctgttg tgattctcat tagttcccct ttcccaagag gcatagggat
    12601 gtgcataata aatgtgctcc tcagaaaata catta
//
LOCUS       DBEJKC010000055        12516 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.055, whole genome shotgun sequence.
ACCESSION   DBEJKC010000055 DBEJKC010000000
VERSION     DBEJKC010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12516
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.055"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(132..1334)
                     /gene="rpsA"
                     /locus_tag="ACL3G6_001683"
     CDS             complement(132..1334)
                     /gene="rpsA"
                     /locus_tag="ACL3G6_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HGR0546173.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFVDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1496..1567)
                     /locus_tag="ACL3G6_001684"
     tRNA            complement(1496..1567)
                     /locus_tag="ACL3G6_001684"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1533..1535),aa:Gln,seq:ttg)
     gene            complement(1577..1657)
                     /locus_tag="ACL3G6_001685"
     tRNA            complement(1577..1657)
                     /locus_tag="ACL3G6_001685"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1621..1623),aa:Tyr,seq:gta)
     gene            complement(1707..1937)
                     /locus_tag="ACL3G6_001686"
     CDS             complement(1707..1937)
                     /locus_tag="ACL3G6_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HGR0546174.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(2105..2749)
                     /gene="pcp"
                     /locus_tag="ACL3G6_001687"
     CDS             complement(2105..2749)
                     /gene="pcp"
                     /locus_tag="ACL3G6_001687"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGR0546175.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(2764..3687)
                     /locus_tag="ACL3G6_001688"
     CDS             complement(2764..3687)
                     /locus_tag="ACL3G6_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0859 family membrane protein"
                     /protein_id="HGR0546176.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGAFAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(3684..4373)
                     /locus_tag="ACL3G6_001689"
     CDS             complement(3684..4373)
                     /locus_tag="ACL3G6_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0858 family membrane protein"
                     /protein_id="HGR0546177.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(4438..5116)
                     /locus_tag="ACL3G6_001690"
                     /pseudo
     CDS             complement(4438..5116)
                     /locus_tag="ACL3G6_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
     gene            complement(5172..6194)
                     /locus_tag="ACL3G6_001691"
     CDS             complement(5172..6194)
                     /locus_tag="ACL3G6_001691"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HGR0546178.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGSVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(6324..8795)
                     /gene="parC"
                     /locus_tag="ACL3G6_001692"
     CDS             complement(6324..8795)
                     /gene="parC"
                     /locus_tag="ACL3G6_001692"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HGR0546179.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(8996..9200)
                     /locus_tag="ACL3G6_001693"
                     /pseudo
     CDS             complement(8996..9200)
                     /locus_tag="ACL3G6_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014166.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            complement(9215..11158)
                     /gene="parE"
                     /locus_tag="ACL3G6_001694"
     CDS             complement(9215..11158)
                     /gene="parE"
                     /locus_tag="ACL3G6_001694"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HGR0546180.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KVGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRSDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            11294..11935
                     /gene="plsY"
                     /locus_tag="ACL3G6_001695"
     CDS             11294..11935
                     /gene="plsY"
                     /locus_tag="ACL3G6_001695"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HGR0546181.1"
                     /translation="MITIILLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(11980..>12516)
                     /locus_tag="ACL3G6_001696"
     CDS             complement(11980..>12516)
                     /locus_tag="ACL3G6_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGR0546182.1"
                     /translation="KKAENLIQGQFEGSKTMEKCYTDVTEFAIPASTQKLYLSPVLDG
                     FNSEIIAYNLSTSPNLEQVQTMLEQVFTEKHYENTILHSDQGWQYRHDSYHRFLESKG
                     IQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKSFQSLKQLEQAIVDYVDYYNNKRI
                     KVKLKGLSPVQYRTKSFG"
BASE COUNT         3604 a         2836 c         2201 g         3875 t
ORIGIN      
        1 acttcaaccc actacagttg acaaagagcc cctttctcga gcttagcttt tcttcaaccc
       61 actacagttg acaaagagcc agaaaaatcc cttgtttagt aaacaaagga ttttgtgaat
      121 tttcaatttg attaaagttc gatgtcacca aacaaatcag ccattgaaaa tcctgtttgt
      181 gtttctggaa gttcgaaatc acgcttttct tgacgtcttg gacgacgtgg acgagcagca
      241 cgtttttctt ctttttgtcc ttcttcttgg gctggacgtt cttcaagagc tttaatagaa
      301 agtgacacgc gttctgcatc tgcgttaact tcaagaactt taacttgaac ttcttgacca
      361 actttaagag cttcttttgg attttcaatc cgtttgtgtg aaatttgtga tacgtgaaca
      421 agtccatcga tacctggcaa tacttcaaca aatgcaccga agtcagtcaa acgtttaact
      481 gttccttcta ctacatcacc tttagccaat ttttgctcaa cgccatccca tggtcctggt
      541 actgttgctt taagtgaaag tgatacacgt ccttcttctt cgttaagatc aaggattttc
      601 acttcaattt cttcaccaac agttacaact gattttggtg atacgttacg ttcatgtgac
      661 aattcagtca agtgaaccaa tccgtcaaca ccaccaaggt cgacgaaagc gccgaagctt
      721 gtgatacgag caactttacc agttacaaca tcaccaacag ccaatttacc gaatacttca
      781 gcgcgagctg ctgcagtagc tgcttcaaca acttcacgac gtgaaaggat gaagcggttt
      841 tctttagcgt taacttcttt gattttagta tcaaattctt gacctacaaa acgctcagca
      901 ttacgtacga aacgagtatc caacattgaa gctgggataa atccacgaac accttcaaat
      961 tctactgaaa gtccaccttt aacggcacgc gttcctttaa cagtaacaac ttcttcttcg
     1021 cgaccaacaa gtttgtccca tgctttgcga gcttcaaggc gttttttaga tacaaggtat
     1081 gtaactgtat cagtatcttt accaactact tgacgaagta caagaacatc caatacttct
     1141 cctactttaa caaagtcatt gatatctgca tcacgatcgt ttgtcaattc gcgaagagtc
     1201 aagacacctt caacaccagt tccagagatt gcaacgttag cttgagtcgc atcaactgtc
     1261 aatacttcag cactaacaac atcaccagtc tcaacttgac taacgctatt tagcaaatct
     1321 tcaaattcat tcatctaaaa aatcctccaa caatcaagtt tttcttaaac ttgacatact
     1381 tataattttt ttcctaagca cccgcaagga catgttcata tcattcacgt ctttcaatta
     1441 taaaaataaa ataccctaag atattttgct ttttatcttg attattacct aagaactggg
     1501 gtagctggat tcgaaccaac gcatgaggga gtcaaagtcc cttgccttac cgcttggcta
     1561 taccccatta atgaaatgga gagagaggga ttcgaacccc cgaacccgaa ggagcggatt
     1621 tacagtccgc cgcgtttagc ctcttcgcta tctctcctac aatcaacatg gactattata
     1681 tcatgaaaat ttcaaaaaaa caagacttat tttgctaaat tataattttc aatcaaaatt
     1741 tccacagctt tttccaattt tttataaaaa ctatcgacat tcccattctt tataatggca
     1801 aattgtccgt ctaattcggc aatttctccg ataacttttt taccgatagt caatgtataa
     1861 ccttcaaaac tgtctttacc aacattaact ttggcatccg ctacttgaat ttcgattttt
     1921 ttatctttct tgctcatttc atacctctct tcactttttc tattttacaa gaaaattcta
     1981 aaactagcaa gaaaaaactc tatatcaggc ttctctgata tagagtttta tgtaaacaac
     2041 ctcaattgat ttagcatagt taatagttag taaacaagca taattgacta tcctttttag
     2101 gttatcagtg agtctcaccg cctactaact gcaaatcctt atctttgtag tctacaatag
     2161 cttcaatagc tacctctatg cctcttacaa tatcacatag actcattcct gcagtattcg
     2221 gcttatttac tacttgttcc atcatatatg gaatatgcat gaaacctgct ctcatattag
     2281 ggaatttttt atccactaaa taaagagctt ggtacatcaa atgattgcaa acaaaggttc
     2341 ctgcactatt ggatacaact gccggaagtc cctgtttttt gatagcttgt accatcgctt
     2401 tgataggtaa actactaaaa taggccgatg ctccatcaat acgaatcggt gtatcaattg
     2461 gttgattgcc ttcgttatca ggtatgcgag catcatcttg attaatagcc actcgttcag
     2521 gtgttaagcc ggtcctgccg cctgcttgtc caatacaaag tacagcatct ggttgatatc
     2581 gtaatatttc tgcctctaaa acttctgacg acttataaaa aaccgttgga atttctaccc
     2641 agcgaacttc agccccatta atctcagatg gtaataattt tacagcctcc aaagctggat
     2701 taatcttttc acctccaaaa ggattaaaac ctgtaaccaa tattttcatt ttattttcct
     2761 ttactaaaat gcgagaaagt acattaagaa tatgtgaata acaatcatta ctagagcaac
     2821 acctgcttga gcctttataa cgccattctg atctttcata tccatcaatg ctgctggtag
     2881 agcgttaaaa ttagcagcca ttggggtcaa taaggtccca caataacctg ctgtcatggc
     2941 aaaagcacca gccacaattg gattagctcc cagagcaaat acaaagggaa ctccaacacc
     3001 tgctgtaata acggtgaatg ctgcaaaagc atttcccata atcattgtga atagaaccat
     3061 tccaagaaca taggccaaaa ctcctataaa gcgactatct gaaggaacaa taccgctaat
     3121 cagatgagag ataacatcac caacacctgc tacagtaaaa atagccccca aagcccctaa
     3181 taattgagga acaataccac ttgttgaaac ttgctgagtc attcgattat tttctgataa
     3241 cagactctta gggtgactat tggtaatcac aagaacagaa attgtagcaa acaaggcggc
     3301 aaggctaatc gaaatcttgc taaattctgg aatcatttgc gctaagacca acgcaagtat
     3361 tgccatcagc ataactggaa taaaaatttt atttttcaac ctgttagatt caatattggc
     3421 tttcatttca tctaaggatg gcaaggttcc gatacggact tgcttaaaca atgttaacag
     3481 cgataatagg attacaataa taccaatact catatttggc atataggaac cacctataaa
     3541 cgtaatagac aatagagtcc aaaatgcaga tgtcccaagt cgaactgggt ttgttttatc
     3601 tttataacta caataggctg tatggagaaa ttgacaacca atcacaatat aggtcaactc
     3661 taatagttgc tttgccaact ctgtcatttt tgttctcctc ccctagtctt ttttgatatc
     3721 aattttttat caaataaata attgtaaatc cccactacaa taagtgttat aacagcaaca
     3781 ataatagatg tagaagcaat ccctgcataa ttgctttcat agcctaactg atctaatgtt
     3841 ccccctatca agaggactcc cccagcacct acaaacgtat tttgagcaaa gaaatttcca
     3901 aaattttcat tcgcagccgc acgcgctttt attgtctcat cttcaacctc tgttaacttt
     3961 ctacctaatt gagactctgc agctgcttct cccataggtt gaaccaaagg tctgacaaac
     4021 tgagggtgtc ctcctagacg aattgaaaag aaaccagcta actctcgaat aaagaaataa
     4081 actgtataga agtttccaac tgtcagacct ttaatctttc gaatcaaatc gattgatcgt
     4141 tgcttgagtc caaaggtttc tgacagcccc acaagaggca aggtaaccat aaaaatcgtg
     4201 agcactcgct gattgctaaa ttcttttccc aaaatctcca aaaattcaac gagagaaaca
     4261 cctgaaacta aagctgtaac caaaccagct aagactactg ttgcaattgt atcaaatttt
     4321 aaaataaaac ccacaacaat gattgctatt cctattaatc taatccactc catatcaaac
     4381 tcctttatat tcaaaatgac agtattttaa aaattttatc aagatcaata ccattcctta
     4441 tttaatgtat ttttctagtt ctttttggta tttgccattt tttaaaaacc tcgttatatt
     4501 cttttgttgt aacaatatct ttttgcaatt tcattccttt aaagatatat ggatccccct
     4561 taataccaac ttgtgagtat ggttttgaga atggtactac gttacttaca actggagaac
     4621 caccagatga agctgttggc atcaataatg aactatctgt cgaccaagct tgagctttgg
     4681 catatttttc atatctcttc tctaggtcag tggtctcaga aacagcatct tctaacaatt
     4741 tcttatattt atccaaacca ggtttagcta caacatcctt atcttttcct ttcgtaatac
     4801 caaggtgttt catggcaaaa ccagattttg gatccataat attcaagtaa gacgctggat
     4861 cttgatagct tggagcccat cctgtactat tcaaatcata gtctttttga gaaggagcaa
     4921 cattgccgta tttatcattt tccatcaaac catcaataac atttccaata acgtctgtcg
     4981 tcgatgttcg agtcgctata ctgtagccca atgatgctgg atctactgca tagacataag
     5041 aaaatgttgt cggtgcatcg gcttctttat cagtttttcc acaagccact aaaatagctg
     5101 acgtgctcag gaccactcct gctgttaaga gccacttttt ctatttcata aaaaatctcc
     5161 ttcggtttat tttaatctac ttttacaatc caaccttctg gcgcttcaat atcgccaaac
     5221 tgaatacccg tcaattcatt atataattta cgcgtcacag aacctacttc tgtttcacta
     5281 tagaatacat ggaaatcatc accatgttga atacctccaa ttggagaaat aaccgctgct
     5341 gtaccacagg cacctgcctc tacaaaacgg tcaagattat caattggaac atcaccctca
     5401 ataggagtta atcccaagcg gtgttctgcc aaataaagca aggaatactt ggtaatagat
     5461 ggcaagatag atggactcaa tggtgttaca aattcattat cagctgtaat tccaaagaaa
     5521 ttagctgatc cgacttcttc aatctttgta tgagttgatg ggtccagata gataacatct
     5581 gagaaatggc gtgacttggc catttttcct ggtaagagac ttgcagcata gtttccacca
     5641 accttagccg cacctgtacc atttggtgct gcacggtcgt actcatcctg aatcaagaag
     5701 ttggttggga ccaaaccacc tttaaagtaa tttccaactg gcatagcaaa gatggtgaaa
     5761 atgtactctt ctgccggttt taccccgata atatctccga caccaatcaa aagagggcga
     5821 agatataagg ttccacctat tccgtatggt ggtacgtatt cttcattcgc acggacaact
     5881 gctttacaag cttctacaaa catgtctgtc ggaacttgtg gcatcaagag acggtcacat
     5941 gtacgttgca ggcgtttagc attttcatca ggacggaaca gttgaacact gccatcctta
     6001 gtacgataag ctttcaaacc ttcaaatgct tgttgtccat agtgaagact tggagaagac
     6061 tctgaaatat gcaaagttgc atcctctgta agctctcctt gatcccattg tccatttttg
     6121 aaatgagcaa gatagcgata aggtaatttc atataggaaa aaccgaggtt ttcccaatca
     6181 atcgttactg tcatattcca ctccttattc taaaaaccta tttcttatat tctacactat
     6241 ttttctaaaa tagcaagtat attttgtaat tttcagaaaa ttcctccaat aaaaaccatc
     6301 ttagaactga ttcttcattt cacttattta tcttcagtaa ctacttcctg aagataagcg
     6361 tcaaaaactt cttcatctga aatcgtgtca gaaatgaagc ttccattgct agtgcgttct
     6421 gacaagttca agtcttgcaa tcggctttca tagattgttc ctttattgga ttggacaagc
     6481 agagtttggt cgttcacatc cacttccgta ctgaagaaat cgccaacaaa tccttgctct
     6541 gcaactgctc ctgccaagaa gacacgatgc ggtttgtttt tcaactcacg caagacttgt
     6601 aatcctcgtt tggcacggct ggttgctaga atttcctcaa tggaaacacg tttcaagctt
     6661 ccacgctggg tcaagaggta gaaggacgaa gtattacaga taaagccaga ttggaggaca
     6721 tcatcttctt tcaaattcat agccttgaca cctgctgcct tagcaccgac aaccggaacc
     6781 tcttcgatat tgaaacgcag ggcataacca ttttgactaa ccaagacaac atcatctagt
     6841 ttaatcggag ccactgctac aatctgatct gtatcgtctt tgagcttagc atacttgaca
     6901 gacttagatc tataggtccg ccatggagtg aattcttttc gctctacccg tttgatttga
     6961 ccaaggcgag tcgctgcaaa gtaggttgtc gcatcgtcaa actgatccag tacttccaca
     7021 taaaggattt cttcattcgt ttcaaagttt gtgatggttt ggctcagatg ctctccgatg
     7081 tccttccaac gaatatctgc caactcatgg attggtctgt agatgacatt tccaagactt
     7141 gtgaacatca agaggtgctg ggttgtcttg gcagattgaa caaaaatcaa acggtcatca
     7201 tcacgcttgc caatttcttc caaggtggaa gccgcaaagg aacgtggact ggtacgcttg
     7261 atgtaacctg ccttggtcac gctgacgtag gtatcttcct cagcgataag actagctgta
     7321 tcaatctcaa ttgctttcgc agtgtcttct aaagaactca aacgaggagt tgcaaatttc
     7381 ttcttgacct cacgaagttc tttcttcatg agattgtaca tagtcctttc atcaccaata
     7441 atagccgcca gcatagcaat cttctcacga agctctgctt cttcttcctg caagacaacc
     7501 acatcggtat tggtcaaacg gtacagttgc aaagttacga tagcctcagc ctgttcttcc
     7561 gtaaaatcat agctaacttt gaggttttcc ttggcgtccg ccttattctc agaagcacgg
     7621 ataagagcaa tgacttcatc caaaatcgaa atcacacgaa tcaaaccttc gacgatatgg
     7681 agacgtttct cagccttttc tttgtcaaag cgtgaacgcg ccaaaatcac ttctcgacgg
     7741 tgagcgatgt agctagacag gattggaaca atcccaacct gacgaggtgt gaaattgtca
     7801 atcgccacca tattaaagtt gtagttgatt tgtaggtcgg tgtacttaaa taagtagttg
     7861 agaacaagct cagtattagc gtctttctta agttcgatag cgatacgaag accatcacgg
     7921 tcagactcat cacgaacctc agcaatccca gctaccttgt tattaacacg aacatcatcg
     7981 attttcttga ctagattggc cttattgatt tcataaggaa tctcagtaat aacgatttgt
     8041 tccttaccac cttttagctt ttcaatttca gtcttggaac gaacaaccac gcgccctttc
     8101 ccagtctcat aagctttctt gatttcatca cgaccctgaa taatagcccc tgtagggaag
     8161 tctggtccag gcaagaattc catgagttta tcaatctttg cagttgggtg gtcaatcatg
     8221 taaactgcag catctatgac ctcagctaaa ttatggggag gaatgtctgt ggcataacca
     8281 gccgaaatcc cagtcgaacc attgaccaag aggtttggaa aggctgctgg caagaccgtt
     8341 ggttctttct ccgtatcgtc aaagttccat gcaaaaggaa ctgtcttttt ctcgatatcc
     8401 tgaagaaggt agcctgcaat ttcagacaaa cgtgcctcag tataacgcat agccgcagga
     8461 ggatctccgt ccatagaacc gttattaccg tgcatttcaa ctagaatctc acgatttttc
     8521 cagttctgtg acatacgaac catggcatca tagatagaag aatccccgtg tgggtggaaa
     8581 ttccccatga tgttcccgac tgacttggcc gacttacggt agctcttgtc aaaagtattg
     8641 ctatccttat tcatagaata aagaatacgg cgctgaaccg gcttcaaccc atcacgaata
     8701 tctggcaaag cccggtcttg aataatgtac ttggagtagc gaccaaagcg ctctcccatg
     8761 atgtcctcca gggacatgtt ttgaatgtta gacataagat acaaagccca taaaatacca
     8821 agtgaaaata gaaaattctt gaagtaagca aactcacaag agaatttatc tttttcacac
     8881 aatatctagg gcgtgttcaa ctcctttcaa agaatgtaga gtaggttttt atgcagtaaa
     8941 agatatttta cgggaattcg tcccgtgttc agttacgata agtaaccaaa ctatcctgtt
     9001 tgtatttttc aatatgaaaa tctggttttc caaaattagt cttagtttgt gtcttagccg
     9061 ctcccttaaa cgcctctttg agataagcac tcatagaaga ttcttcatta ataattctgc
     9121 aattttttca aaccaagatt ttcaaactgc tttttcacat agtcattcac atccgactct
     9181 aatttccagt ttactaacat attattttct ttcattaaaa cactgtcgct tcttctagcg
     9241 taaacttgac attatcttca atccatttac ggcgtggttc taccttatct cccatgagaa
     9301 cattgacgcg acgttcggcg cgcgctaaat cttcaattgt gacacggatg agggtacgtg
     9361 tttctgggtt catggttgtt tcccagagct ggtccgcatt catctcacca agtcctttgt
     9421 atcgttggag ggtagcgcct ttaccgaact gtttacgtag ttcttctagt tctccgtccg
     9481 tccaagcgta ggccacttct tctttcttgc ctttaccttt ggacatcttg taaagaggtg
     9541 ggagggcaat atagacatga cctgcctcga ctagcggacg catgtaacgg tagaaaaatg
     9601 tcaagagcaa ggtctggata tgggcaccgt cggtatccgc atcggtcatg ataatgatct
     9661 tatcatagtt ggcatcttca atagagaagt ctgctccaac acccgcacca atggtataaa
     9721 tcatggtatt gatctcttca tttttgagga tatccgccat cttggccttg gctgtattga
     9781 taaccttacc acgaagaggt agaatagcct ggaacttgcg gtcacgacct tgtttggcag
     9841 aaccaccggc agagtccccc tcaactagat agagttcatt cttagcagga ttcttagatt
     9901 gggctggggt caatttccca gacaacaagc ccttatcttt cttgtttttc ttcccatttc
     9961 ggctctcatc acgcgcctta cgtgctgctt cacgagcatc acgggccttg atagccttgc
    10021 ggatgaggtt agaagctaat tccccatttt ccataaggaa aaaggtcaac ttatcagcca
    10081 ctattccatc cacaactggg cgagctaagg ggcttcctag tttatccttg gtctgtcctt
    10141 caaactgcaa gtgttcttca ggaactaaga tagaaagaac ggccgctagt ccctcacgat
    10201 agtctgaacc ttcaaggttt ttatcttttt ccttgagaag acctgtttta cgtgcatagt
    10261 cattcatgac cttggtaatg gcagacttga gtcctgtctc gtgcgttcca ccgtccttgg
    10321 tgcgaacgtt attgacaaag gatagaatgt tatctgagaa tccgtcattg tactggaggg
    10381 ctacttccac ttgaaaacca ttgtcttccc cttcaaagta aagaactggc gtcaagattt
    10441 ccttatcttc gttgagataa gaaacaaaat cttgtactcc attctcatag tggaactcaa
    10501 tcgcttcatc tgatcgcttg tccgttaaag acaaggtcac atttttcaag agaaaggctg
    10561 attcattaag gcgctctgaa atggtattgt acttgaaatc tgtcgtagaa aagatagtcg
    10621 cgtcaggcat aaaagtaact ttggtgcctg ttttagactt gggtgctgta ccgactttct
    10681 tcaaagtcgt gacaggtttt ccaccatttt caaaacgttg cttgtaaact gcgccatcac
    10741 gggtaatttc aacttctaac cagctagaaa gggcgttaac aacggaagaa cccactccgt
    10801 gaagtccacc tgatgtctta tagccacctt gaccgaattt ccctccggca tgaagaatgg
    10861 taaagataac ctcaacagtt ggaattccca tagcgtgcat acctgtcggc atcccacgtc
    10921 catggtcttg aaccgttaga ctaccgtctt tattgatagt tacatcaata cgatcaccaa
    10981 acccagacaa ggcttcatcg actgcattat caacgatttc ccaaactagg tgatgaagac
    11041 cagcgccatc ggtcgatcca atatacatcc ctggacgttt tcggaccgca tccaaccctt
    11101 ctagcacctg aatagcatca tcattataat tgttaatatt gatttccttt tttgacacaa
    11161 ggaacctcct attcgttcat ctttactatt ctacaggttt tccaaggatt ttgcaaaatt
    11221 tttctttctc cgatgtgaca atttcagcag agattctctg cttttctttc ccaattcatg
    11281 atataatagg agtatgatta caataatttt attaatccta gcctatctgc tgggttcgat
    11341 tccatctggt ctctggattg gacaagtatt ctttcaaatc aatctacgcg agcatggttc
    11401 tggtaacact ggaacgacca ataccttccg cattttaggt aagaaagctg gtatggcaac
    11461 ctttgtgatt gactttttca aaggaaccct agcaacgctg cttccgatta tttttcatct
    11521 acaaggcgtt tctcctctca tctttggact tttggctgtt atcggccata ccttccctat
    11581 ctttgcagga tttaaaggtg gtaaggctgt cgcaaccagt gctggagtga ttttcggatt
    11641 tgcgcctatc ttctgtctct accttgcgat tatcttcttt ggagctctct atcttggcag
    11701 tatgatttca ctgtctagtg tcacagcatc gatcgcggct gttatcgggg ttctgctctt
    11761 tccacttttt ggttttatcc tgagtaacta tgactctctc ttcatcgcta ttatcttagc
    11821 acttgctagt ttgattatca ttcgtcataa ggacaatata gctcgtatca aaaataaaac
    11881 tgaaaatttg gtcccttggg gattgaacct aacccatcaa gatcctaaaa aataaaatgc
    11941 cagttctgtg aactgccccc caaaagttag acaaataatt tatccaaagg atttagttct
    12001 gtactgcaca ggactaagtc cttttagttt taccttaatt cgtttattgt tgtagtaatc
    12061 aacatagtct acaatagctt gttccaattg cttaagcgac tgaaacgact tctcataacc
    12121 gtaaaacatt tccgatttca gaatcccaaa gaaggactcc atcataccat tgtctgggct
    12181 gttaccctta cgtgacatag atgcttgaat tcccttactc tctaggaacc gatgataaga
    12241 atcgtgtcgg tattgccagc cttggtcact atggagaatc gtattctcat agtgcttctc
    12301 tgtgaatacc tgttccaaca ttgtttgtac ttgttctaag ttgggtgaag ttgaaagatt
    12361 ataggcgata atttcgctat taaagccatc taaaactggt gataagtaaa gcttttgagt
    12421 acttgctgga atggcaaatt ctgtcacatc tgtgtagcac ttttccattg ttttagagcc
    12481 ttcaaattgg ccttgaatga gattctctgc tttctt
//
LOCUS       DBEJKC010000056        11646 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.056, whole genome shotgun sequence.
ACCESSION   DBEJKC010000056 DBEJKC010000000
VERSION     DBEJKC010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11646
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.056"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            125..379
                     /gene="blpM"
                     /locus_tag="ACL3G6_001697"
     CDS             125..379
                     /gene="blpM"
                     /locus_tag="ACL3G6_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HGR0546183.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            395..598
                     /gene="blpN"
                     /locus_tag="ACL3G6_001698"
     CDS             395..598
                     /gene="blpN"
                     /locus_tag="ACL3G6_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HGR0546184.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            842..991
                     /gene="blpO"
                     /locus_tag="ACL3G6_001699"
     CDS             842..991
                     /gene="blpO"
                     /locus_tag="ACL3G6_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HGR0546185.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            1095..1214
                     /locus_tag="ACL3G6_001700"
     CDS             1095..1214
                     /locus_tag="ACL3G6_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGR0546186.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            2000..2383
                     /locus_tag="ACL3G6_001701"
     CDS             2000..2383
                     /locus_tag="ACL3G6_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HGR0546187.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            2435..3124
                     /locus_tag="ACL3G6_001702"
     CDS             2435..3124
                     /locus_tag="ACL3G6_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0546188.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3166..3399
                     /gene="blpZ"
                     /locus_tag="ACL3G6_001703"
     CDS             3166..3399
                     /gene="blpZ"
                     /locus_tag="ACL3G6_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein BlpZ"
                     /protein_id="HGR0546189.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFLGAGYVVGFWLLILNENQRAN"
     gene            3550..4161
                     /locus_tag="ACL3G6_001704"
     CDS             3550..4161
                     /locus_tag="ACL3G6_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0546190.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGDFFQNESALIIVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFVPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYKSWPLLYYL"
     gene            4322..5116
                     /gene="ccrZ"
                     /locus_tag="ACL3G6_001705"
     CDS             4322..5116
                     /gene="ccrZ"
                     /locus_tag="ACL3G6_001705"
                     /EC_number="2.7.1.15"
                     /EC_number="2.7.1.229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0051726 - regulation of cell cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell cycle regulator CcrZ"
                     /protein_id="HGR0546191.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETVPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5113..5748
                     /gene="trmB"
                     /locus_tag="ACL3G6_001706"
     CDS             5113..5748
                     /gene="trmB"
                     /locus_tag="ACL3G6_001706"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HGR0546192.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            5874..6353
                     /gene="rimP"
                     /locus_tag="ACL3G6_001707"
     CDS             5874..6353
                     /gene="rimP"
                     /locus_tag="ACL3G6_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HGR0546193.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            6397..7533
                     /gene="nusA"
                     /locus_tag="ACL3G6_001708"
     CDS             6397..7533
                     /gene="nusA"
                     /locus_tag="ACL3G6_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HGR0546194.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            7555..7848
                     /locus_tag="ACL3G6_001709"
     CDS             7555..7848
                     /locus_tag="ACL3G6_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HGR0546195.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            7841..8140
                     /locus_tag="ACL3G6_001710"
     CDS             7841..8140
                     /locus_tag="ACL3G6_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HGR0546196.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8157..10949
                     /gene="infB"
                     /locus_tag="ACL3G6_001711"
     CDS             8157..10949
                     /gene="infB"
                     /locus_tag="ACL3G6_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HGR0546197.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11200..11550
                     /gene="rbfA"
                     /locus_tag="ACL3G6_001712"
     CDS             11200..11550
                     /gene="rbfA"
                     /locus_tag="ACL3G6_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HGR0546198.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3576 a         2024 c         2650 g         3396 t
ORIGIN      
        1 ttgcaattca agacgtttcg atgactattc aagatctgga tgaaaaattt taaaaaacga
       61 tgatatacta aacttgtcaa agttacaaca agacaaaaat taaaaataaa aaagagtatt
      121 tgtcatggat acaaaaatta tggaacaatt tcatgaaatg gatataacta tgttatctag
      181 tattgaagga ggcaagaata attggcaaac taatgtctta gaaggtggtg gtgctgcttt
      241 tggtggctgg gggctaggga cagctatttg tgctgcgagt ggtgttggag caccatttat
      301 gggagcatgt ggatacatag gagctaaatt tggtgtggat ctttgggcag gagtaacagg
      361 ggcaacgggt ggattttaat aaaaggagac ttgtatgaat acttattgta atataaatga
      421 aacaatgctg agtgaggttt atggaggtaa ttccggagga gcagctgtag ttgctgcttt
      481 aggttgtgca gcgggtggag tgaaatatgg gagacttcta ggaccatggg gcgctgcaat
      541 aggaggaatt ggaggagcag tggtttgtgg atatttagcc tataccgcta catcataaaa
      601 atgaaagcta aattttatga aggctatatt ctttattatt ctcttcgctt ttcaaaccta
      661 tcttatttat ctatccataa gtatctccga taaaaaacaa aagactattg aattaacatc
      721 attgaattgt tttgtcatat tatttctaat ctatgataaa ttaatttttc tctttattgc
      781 ctatgttttt ttgataattt ttatattaaa cttgttccgt aactgaaaag tgatatacta
      841 tatggataca aaaatgatgt cacaatttgc agttatggat aatgaaatgc ttgcttgcgt
      901 tgaaggtgga gatattgatt ggggaagaaa aattagttgt gcagcagggg ttgcatatgg
      961 cgcaattgat gggtgtgcaa caacggtttg acatttctat tgggaccatt tgctatagga
     1021 ataggtgtaa ctggtgctgc gggaggagct atacttggag gtgtggccta tgcagcgaca
     1081 tgttggtggt aattatggat tttaaaagtt ttattattgg tttagtagtt ggtatatttg
     1141 gtccttatat ggatgactta attagaaaaa tattttcaaa atcttccaaa aaggatacgg
     1201 atagtactct ctaaaaaata aatttctccc ctgtatttgc tagcttaatt tacaggggag
     1261 tttctttaat attgtttcgc ctgtcaaaat gatatgtgat agcaggatga aaagtctaca
     1321 aacaagttgg tatcaataca atataaagag gaaagtatgt ttttaatgct tactttttaa
     1381 attttttaac aattcaagat gtttcgatga caattcaaga tttggatgaa aaattttaaa
     1441 aaacaatgat atactaaact tgtcaaagtt gcaacgggtg ctgctacatt atgttaaaaa
     1501 tcgctcttga ttgataagtt ggatttgtta ggaaaggagt aaataattat ggataagaaa
     1561 aagatagttt cgactataat atgtatagta tttcttgtag tgtcagtaga taattttttt
     1621 agagacttaa ccccgttact gttcatttta aatattattg gcctgtcttg cttttcagtg
     1681 ctaacataca ttaacataaa agagatactc ttaaatataa gtaaatgatg atttggttag
     1741 tcctagaacc aatcaactta tgtttatcgg cttggcagat tttatgtttg tcatttgttt
     1801 gtatagaggt atttcagaaa cagaattcta tcaacaacta atcgcttata taggtgtatt
     1861 ctctgcttgt ttatcacgct tctgctcatg tggggcttga agtattataa aaagtagctt
     1921 tctatccttt tctgacagga tatttgagta gaaggctcta ttaaattgtt agtgaaataa
     1981 atgaatggag gtatttaata tgaaatacag attatttttt gttattttct tgagtagtgt
     2041 gttggatatt cttttaggga catttttaca aatctctatc gtatctattg ggtggcttgt
     2101 tctttacagt ggtttgtttg aagcaggagt tttccttctt gctaataaag gggtggcggt
     2161 aaaaatcaag gaagtagata ttcgaaatcg ctttaaattt atttttggaa aaaccttatg
     2221 gtttcaaatt cttttgctca tctttttgat aatcaaactt tatcttggtt tggatgcgag
     2281 gttgatttta ttctatggac atattttcat tgtctttaat gccttaatgt atctattatc
     2341 tagtagtcag gttagcctta aaaaaaacaa actgtcttct taatcttaca gcagtagagc
     2401 ctgacaaggt gaggtcatag tagggaggat ttctatgaaa aagtatcaac ttctattcaa
     2461 aataagtgca gtcttctctt acttattttt cgtatttggt ctttctcagc tgacgcttat
     2521 cgtccaaaac tattggcaat tttcttctca gataggcaat ttattctgga ttcaaaatat
     2581 cttgagttta ctttttattg gagtcatgat tgtggttctt gttaagacag gccatggtta
     2641 tctcttccgc attccaagaa aaaaatggct ttggtattcg attttgacag tattagtggt
     2701 agtgttacag atctctttta acgttcagac agctaaacat gttcagtcaa ctgcggaagg
     2761 ttgggctgta ttgattggtt atagtgggac taactttgca gagctaggta tttatatagc
     2821 cctgttcttt ctggttccac tgatggaaga attgatttat agaggattac tgcaacatgc
     2881 tttctttaag cattcgcgat ttggtcttga tttgcttctt ccttctattt tatttgctct
     2941 ccctcatttt tcaagcctgc ctagtctgtt agatatcttc gtctttgcaa cagttggaat
     3001 catctttgct ggtttgaccc gctataccaa gagcatttat ccatcctatg cggtgcatgt
     3061 gatcaataat attgtagcga ccttcccgtt tttgctcact tttctacata gggtcttggg
     3121 gtaaaaaaac aaaaggcttg cttttcagcc atagaggagg tcatcatgta taaacactta
     3181 tttttcctag attccaaaac tttagatcgg ttgacaccct atattctagt cttggcttct
     3241 gacaccattg cttttaatgt ttttgtgcta acctttgtat ctgcggtggt ttttaatttc
     3301 ctaaattcca tgctagcttt aatggctatc ttcttaggag ctggctatgt ggtcggattt
     3361 tggttactaa tactcaatga aaatcaaaga gcaaactagg aaactagccg caggctgtac
     3421 ttgagtacgg caaggcgacg ttgacgtggt ttgaatttga ttttcgaaga gtataaaatg
     3481 gtttgttttg gaaaggctag aactaaagga tgacgtgtag gaagtctgtt tgttgaggag
     3541 gataatttta tggagttttt tgataaattt catgccttgt gttttggatt tttagtacta
     3601 ataattgtca ttacagttcc ttatacgatt aaccatgggg atttttttca aaatgaatct
     3661 gcattgatta ttgtaagtct tcttgtaacc tcgctgagtg ttgcttatgc tagaaagttt
     3721 gaaatgattt cttttgggat gttaagcaag aaacaacttt tgcttttcat tgcaatcttt
     3781 cttctaagtg tgcttgagac gctggtttat attcatttct tcgctgtttc ttctggctca
     3841 ggggtccaac acttggcgga agtcagcaga ggaatttccc tgtctttgat tttgactacc
     3901 tcagtttttg tccccatcca ggaggaactc attttcagag gacttcttca aggtgcggtt
     3961 tttgacaatt cttggttagg gcttgtgcta acttcctctc tcttttcttt catgcatgga
     4021 ccttctaatg tcccttcgtt tattttttat ctacttgggg gcttgttact gggctttgct
     4081 tataaaaaga gtcaaaacct atgggtttct actctagtac atatgcttta caaaagttgg
     4141 ccactcttat attatttata aaaattatga aaaggtaagc agaagacggt gcttaccttt
     4201 ttcaagctat aatgataccc aagccaatcc agaggctttt ctttgagaat cgggttagag
     4261 tggttgacga ataggccaaa aactagtaga atagtaagga aactttatac ggaggaaaga
     4321 aatggatttg ggtgataatg agctaacact gactcccata cctgggaaaa gtggcaaggc
     4381 ttatatgggt agctatcctg atgggaagcg catctttgta aaaatgaaca cctctccaat
     4441 cctacctggt ctagctagag aacaaattgc tccacaatta ttatggagtc gtcgtttggc
     4501 agatgggcgt gatatgtgtg ctcaagaatg gttgacaggc aagatattga ccccctatga
     4561 tatgaatcgt aagcaaatcg tcaatatttt aacccgtctt catcgctcac gtccgttgat
     4621 gacacaattg agtcgtttgg gctatgccat ggaaacacct gtagatttac tacagtcttg
     4681 gcaggaaacg gttccagatg ctttgcgtaa aaatcatttt atcagtgaag tgatggctga
     4741 tttacgtcag actattccag gatttagaga ggaccatgcg accattgtcc atggagatgt
     4801 acgacatagt aattggattg agacagatag tggcttgatt tatttagtag attgggattc
     4861 ggttcgcttg accgatcgca tgtttgatgt ggcccatatg ctctgccatt atatttcaga
     4921 acatcagtgg aaggaatggt tgacctacta cggttacaag tacaatcaaa cggtattaag
     4981 taaattgtat tggtatggtc aattgtctta tttgagtcag atttccaagt attatatgaa
     5041 ccaagattta gaaaatgtca atcgggagat tcatggtttg cgtcatttcc gagacaagta
     5101 tggaaagaga agatgagagt tagaaatcgt aaaggggcaa cagaattact agaggcaaat
     5161 ccccagtatg tggtcctcaa tcccttggaa gccaaggcaa aatggcggga cttgtttggc
     5221 aatgataatc ccattcatgt ggaagttgga agtggaaagg gtgcctttgt ttcaggtatg
     5281 gccaagcaaa accctgacat caactatatc gggattgata ttcaaaagtc tgttttgagc
     5341 tacgctttgg acaaggtgct tgaagctgga gtgtctaaca tcaagctctt gtgggtagat
     5401 ggttctgact tgactgacta ctttgaagac ggtgagattg atcgcttgta tctgaacttt
     5461 tcagatccat ggccgaaaaa acgccatgaa aagcgtcgtt tgacctacaa gacctttttg
     5521 gataccttca aacgtatctt gcctgaaaat ggagaaattc atttcaagac ggataaccgt
     5581 ggcttgtttg agtacagttt agtgagcttt tctcaatatg gcatgaaact caatggtgtc
     5641 tggctagatt tgcatgccag tgattttgaa ggcaatgtca tgacagaata cgagcaaaaa
     5701 ttctcaaaca aggggcaagt tatctaccga gttgaggcag aattttaaga gatagcctaa
     5761 aattaggctg tacaagtgct tttgctttac ataagttggc aaacgtgcta tactgatagt
     5821 aagaatatga aaagtgaggc ggggaaatat cttcgcctct tgcttatgag gaggtggacg
     5881 caatcgcaac aatcgtagaa ttagtcagag aagttgtaga acctgtcata gaagctcctt
     5941 ttgaactcgt ggatatcgag tatggaaaga ttggcagtga catgattctc agtatttttg
     6001 tagataaacc cgaaggaatt accttgaacg acacggcaga cttgacagaa atgatcagtc
     6061 ctgtcctaga caccatcaag ccagatccct tcccagaaca atatttccta gaaattacca
     6121 gtccaggttt ggaacgtcct ttgaaaacca aggatgccgt cgctggagcg gttggaaaat
     6181 acatccatgt cgggctctac caagccatcg ataagcaaaa ggtctttgaa ggaactttgt
     6241 tggccttcga agaggacgag ttgactatgg aatatatgga caagacgcgt aagaaaaccg
     6301 tccaaattcc atacagttta gtatcaaaag cacgtttagc agttaaatta tagaaaaaga
     6361 aaggatagct tttgaggatt caaaagtgaa gaaaacatga gtaaagaaat gctagaggcc
     6421 ttccgcattt tggaagaaga caagggaatc aaaaaagaag atatcatcga cgcagtagta
     6481 gagtcgcttc gttccgctta tcgcagacgc tatggtcagt cagacagcgt agctattgac
     6541 ttcaacgaaa aaacaggtga ctttacagtt tatactgtcc gtgaagttgt tgatgaagta
     6601 tttgatagcc gtttggaaat cagcttgaaa gatgctcttg ccattaattc agcttatgaa
     6661 cttggagaca aaatcaagtt tgaagaagca ccagctgagt ttggtcgtgt agcagcccaa
     6721 tctgccaaac aaaccatcat ggaaaaaatg cgcaagcaaa cacgtgccat cacttacaat
     6781 acttacaaag aacatgagca agaaatcatg tctggtacag tagaacgctt tgacaaccgc
     6841 tttatctatg tcaaccttgg tagtatcgaa gcccaattgt caaaacaaga ccaaattcct
     6901 ggagaagttt ttgcttctca tgatcgtatc gaagtttatg tttacaaggt tgaagacaac
     6961 cctcgtggtg tgaacgtctt tgttagccgt agccatccag aaatgatcaa acgtttgatg
     7021 gagcaagaaa ttccagaagt ttatgatgga actgttgaaa tcatgagcgt ggctcgtgaa
     7081 gcaggtgacc gtacgaaggt tgctgttcgt agccacaatc caaacgtgga tgctatcggt
     7141 acaatcgttg gacgtggtgg tgctaatatc aagaagatta ctagcaaatt ccacccagct
     7201 cgttacgatg ctaaaaatga ccgcatggta ccaatcgaag aaaatatcga tgttatcgag
     7261 tgggtagcag atccagctga atttatctac aatgccatcg ctcctgctga ggttgaccaa
     7321 gttatctttg atgaaaacga cagcaaacgt gccttggtgg ttgttccaga taacaagctt
     7381 tctcttgcca ttggtcgtcg tggacaaaac gtgcgcttgg cggctcactt gactggttac
     7441 cgtatcgata tcaagtctgc tagcgaattt gaagccatgg aagacgctgc ttcagtagag
     7501 ttggaagtag aaaacgatac tgtagaagaa taaaagctgc tagaggaggg aaagatgaaa
     7561 acaagaaaaa tccctttgcg caagtctgtt gtgtctaacg aagtgattga taagcgtgat
     7621 ttgctccgca ttgtcaagaa caaggaagga caagtcttta ttgatcctac gggcaaggcc
     7681 aatggccgcg gcgcttatat caaactagac aatgcagaag ccctagaggc gaaaaagaag
     7741 aaggtcttta accgcagctt tagcatggaa gtggaagaaa gcttttatga cgagttgatc
     7801 gcttatgtgg atcacaaagt gaaaagaaga gagttgggac ttgaataagc aaaagataag
     7861 taatctcttg gggcttgctc agcgagcagg gcgcatcata tcgggtgaag aattggtggt
     7921 caaggccatt caagacggca aggccaagtt ggtctttcta gctcatgatg ctggacccaa
     7981 tctgaccaag aagattcaag ataaaagtca ttattatcaa gtagaaattg taaccgtgtt
     8041 ttcaacactg gaattaagca tagcagtcgg gaaatcgaga aaggttttgg ctgtaacaga
     8101 tgctggattt acaaagaaaa tgaggtctct tatggaatag aagaggagga catgatttgt
     8161 ctaagaaaag attgtacgaa atcgcaaaag aacttggaaa agaaagtaaa gaagttgtag
     8221 cgcgtgcaaa agagttaggc ttggatgtga aaagccactc atcaagtgtg gaagaagctg
     8281 tcgctgcaaa aattgctgcc agctttaagc ctgcagctgc tccgaaagta gaagcaaaac
     8341 ctgcagcacc aaaagtaagt gcagaaaaga aagccgaaaa atctgagcca gctaaaccag
     8401 ctgtagctaa ggaagaggca aaaccggctg agccagttgc tccgaaaaca gaaaaagtag
     8461 cagtgaaacc gcaaagtcgt aatttcaagg ctgagcgtga agcccgtgct aaagagcagg
     8521 cagaacgacg caagcaaaat aagggcaata accgtgacca acaacaaaac ggaaaccgtc
     8581 agaaaaacga cggccgtaat ggtggaaaac aaggtcaaag caaccgcgac aatcgtcgct
     8641 ttaatgacca agctaagaag cagcaaggtc agcaaaaacg tagaaatgag cgccgtcagc
     8701 aagaggataa acgttcaaat caagcggctc cacgtattga ctttaaagcc cgtgcagcag
     8761 ccctaaaagc agagcaaaat gcagagtacg ctcgttcaag tgaggaacgc ttcaagcagt
     8821 atcaggctgc taaagaagcc ttggctcaag ctaacaaacg caaggaacca gaggaaatct
     8881 ttgaagaagc ggctaagtta gctgaacaag cacagcaagt tcaagcagtg gttgaagtcg
     8941 tccctgagaa aaaagaacct gcagtggata cacgtcgtaa aaaacaagct cgaccagaca
     9001 aaaatcgtga cgattatgat catgaagaag atggtcctag aaaacaacaa aagaatcgaa
     9061 gtagtcaaaa tcaagtgaga aatcaaaaga atagtaactg gaataacaac aaaaagaaca
     9121 aaaaaggcaa taacaagaac aaccgtaatc agactccaaa acctgttacg gagcgtaaat
     9181 tccatgaatt gccaacagaa tttgaatata cagatggtat gaccgttgcg gaaatcgcaa
     9241 aacgtatcaa acgtgaacca gctgaaatcg ttaagaaact tttcatgatg ggtgtcatgg
     9301 ccacacaaaa ccaatccttg gatggggaaa caattgaact cctcatggtg gattacggta
     9361 tcgaagccaa acaaaaggtt gaagtggata atgctgacat cgaacgtttc tttgtcgaag
     9421 atggttatct caatgaagat gaattggttg agcgtccacc agttgttact atcatgggac
     9481 acgttgacca cggtaaaaca acccttttgg atactcttcg taactcacgt gttgcgacag
     9541 gtgaagcagg tggtattact cagcatatcg gtgcctacca aatcgtggaa aatggtaaga
     9601 agattacctt ccttgataca ccaggacacg cggcctttac atcaatgcgt gcgcgtggtg
     9661 cttctgttac cgatattacg atcttggtcg tagcggcaga tgacggggtt atgcctcaga
     9721 ctattgaagc catcaaccac tcaaaagcag ctaacgttcc aatcatcgta gctattaaca
     9781 agattgataa accaggtgct aacccagaac gcgttatcgg tgaattggca gagcatggtg
     9841 tgatgtcaac cgcttggggt ggagattctg aatttgttga aatctcggct aaattcaacc
     9901 aaaatatcga agaattgttg gaaacagtcc ttcttgtggc tgaaatccaa gaactcaaag
     9961 cagacccaac agttcgtgcg atcggtacgg ttatcgaagc gcgcttggat aaaggaaaag
    10021 gtgcggtcgc aacccttctt gtacaacaag gtaccttgaa tgttcaagac ccaatcgttg
    10081 tcggaaatac cttcggtcgt gtccgtgcta tgaccaacga ccttggtcgt cgtgttaaag
    10141 ttgctggacc atcaacacca gtctctatca caggtttgaa cgaagcaccg atggcgggtg
    10201 accactttgc cgtttacgag gatgaaaaat ctgcgcgtgc agcaggtgaa gagcgtgcca
    10261 aacgtgccct catgaaacaa cgtcaagcta cccaacgtgt tagccttgaa aacctctttg
    10321 atacccttaa agctggggaa ctcaaatctg ttaatgttat catcaaggcc gatgtacaag
    10381 gttctgttga agccctttct gcctcacttc aaaagattga cgtggaaggt gtcaaagtga
    10441 ctatcgtcca ctcagcggtc ggtgctatca acgaatcaga tgtgaccctt gccgaagctt
    10501 caaatgcctt tatcgttggt ttcaacgtac gccctacacc acaagctcgt caacaagcag
    10561 aagctgacga tgtggaaatc cgtcttcaca gcattatcta caaggttatc gaagagatgg
    10621 aagaagctat gaaagggatg cttgatccag aatttgaaga aaaagttatt ggtgaagcgg
    10681 ttatccgtga aaccttcaag gtgtctaaag tgggaactat cggtggattt atggttatca
    10741 acggtaaggt tgcccgtgac tctaaagtcc gtgttatccg tgatggtgtc gttatctatg
    10801 atggtgaact cgcaagcttg aaacactata aagacgacgt taaggaagtt acaaacggcc
    10861 gtgaaggtgg attgatgatc gacggctaca atgatattaa gatggatgat gtgattgagg
    10921 cgtatgtcat ggaagaaatc aagagataag attttttgct cctttcttag gtggtgaggg
    10981 acgcaagcaa accgatggtt tcattgctta tttttgagcc tagggtctca aaaataccct
    11041 gtgatgggac tgataaatca gttccatcac tttcaccacg gcgaaagaag cagatgactt
    11101 caaattgaac ttcgtttcaa tttaaactga aaatcaagaa gtttaaaata gctaggtctg
    11161 ctggcctagc ttttggttca aagtagagaa aggaatatca tggcaaatca tttccgtaca
    11221 gatcgtgtgg gcatggaaat caagcgtgaa gtcaatgaga ttttgcaaaa gaaagtccgt
    11281 gatccacgtg tccaaggtgt gaccatcaca gatgttcaga tgctgggtga cttgtctgtt
    11341 gccaaggttt attacaccat tttgagtaac cttgcttcgg ataaccaaaa agcccaaatc
    11401 gggcttgaaa aagcaactgg taccatcaaa cgtgaacttg gtcgcaattt gaaattgtac
    11461 aaaatcccag atttgacctt cgtcaaagac gagtccatcg agtatggaaa caagattgac
    11521 gagatgctac gcaatctgga taagaactaa agaagagggg ttgcccctct tttttggtgg
    11581 aggaaaatag gttgaatttg aaatggaaaa atattctttt ataatagatt gaaactagaa
    11641 tagtac
//
LOCUS       DBEJKC010000057        11427 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.057, whole genome shotgun sequence.
ACCESSION   DBEJKC010000057 DBEJKC010000000
VERSION     DBEJKC010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11427
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.057"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(128..1759)
                     /locus_tag="ACL3G6_001713"
     CDS             complement(128..1759)
                     /locus_tag="ACL3G6_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HGR0546199.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2052..6962
                     /locus_tag="ACL3G6_001714"
     CDS             2052..6962
                     /locus_tag="ACL3G6_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HGR0546200.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEAASAAKPEEKAGEVVAETPS
                     AEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNS
                     WEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHAS
                     VGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQ
                     ERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYS
                     KEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWD
                     KAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAP
                     DTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTT
                     SFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGG
                     NSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDD
                     ADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQ
                     EPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIY
                     LPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFEWGMTVQDTSLPRPLAENIVPG
                     ATVIGSTFPDTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDH
                     AGAGGESVNDGLMNTKDFDLYYKDADGKWKLAKEVRGNKAHVTDITLDKPITAQDWRL
                     NVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGA
                     TITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSV
                     PKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSG
                     FDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSL
                     DLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGHEVNFDVLVSP
                     KAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLKDHETSTQDQV
                     NDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNK
                     ALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLK
                     VERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFL
                     PEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNKVLPKPTYQPA
                     SDQQKAPKLEVQEEKVAFHRQEHENTEMLVGEQRVIIQGRDGLLRHVFEVYENGQRRL
                     RSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQLPNTGTADANE
                     ALIAGLASLGLASLALTLRRKREDKD"
     gene            7052..8248
                     /gene="pgk"
                     /locus_tag="ACL3G6_001715"
     CDS             7052..8248
                     /gene="pgk"
                     /locus_tag="ACL3G6_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HGR0546201.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8384..8911
                     /locus_tag="ACL3G6_001716"
     CDS             8384..8911
                     /locus_tag="ACL3G6_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGR0546202.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            8988..9344
                     /gene="glnR"
                     /locus_tag="ACL3G6_001717"
     CDS             8988..9344
                     /gene="glnR"
                     /locus_tag="ACL3G6_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HGR0546203.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9381..10727
                     /gene="glnA"
                     /locus_tag="ACL3G6_001718"
     CDS             9381..10727
                     /gene="glnA"
                     /locus_tag="ACL3G6_001718"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HGR0546204.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTVIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10823..10942)
                     /locus_tag="ACL3G6_001719"
     CDS             complement(10823..10942)
                     /locus_tag="ACL3G6_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HGR0546205.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            10907..11056
                     /locus_tag="ACL3G6_001720"
     CDS             10907..11056
                     /locus_tag="ACL3G6_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
                     /protein_id="HGR0546206.1"
                     /translation="MEKFNFKNNIGQENKLLQIEIYKFTNFCKLQNYTSVNIFSKDIF
                     EAIVN"
BASE COUNT         3642 a         2106 c         2483 g         3196 t
ORIGIN      
        1 tagaggtgta ctattctagt ttcaatatac tatatatctg cagaatactc tttcagtttc
       61 attcagccta gtcttgctta ggaaaaagta agaagccatc caattatgat ggatagcttc
      121 ttggttctta gatttgttct gcaaaaacct tttcagcaag gttcatagcg tggtctgata
      181 cacgagtgta gtgtgagatg atgtcgataa agttgacccc agcttgtgtt gaacattcgc
      241 ctttgttgag gcgtttgatg tgggtttttc tgagaacacg ttctatctta ttgattgctt
      301 catgacgttc tacaagactg cgtgcttttt caatatcatt gttttccaca ctatccagag
      361 catctttgat aaagtcacta gtttggcggt aaacttcctc taattctttc aaggcggcat
      421 cagaaaattc aacatttttc cgttgaagat agtcagtcag attgagtaga gcctccgtgt
      481 ggtctccaat ccgttccaaa tcacgggagg aatcaaggat attggtgagc acttcacttt
      541 ctttttggct gagagcttcg cttgaaaggg caatgagata acgtgttaat tgctcatcga
      601 tggtgttaat tgcttcttcg gttttatgcc ctttttcagc aactttttca tccaagtcaa
      661 tgatgtactt ataggaaagg tcaaaggctt tagcagcgta gtttcctaag tgcaagagct
      721 cttttttagc atttcctaga gcgatagatg gggcttgttt gatgaaatgt tcatcaagat
      781 ataagggttc gtatttgaca acctcgtcct ctccaggaat aatcttggtt acaaagtaag
      841 ccagagctcc gataaatgga aattggacaa tggtgttggt aatattaaag gttccgtgag
      901 caaaggcgat ggtcatttcc ggtgctagat ttagcgtagc ttcaaaccaa tgaatcagga
      961 cagtaaaagg aactagaaaa ataacgcaga cgactgttcc gataacgttg aaggcaacat
     1021 gagctcctgc tacccgttta gctgcaatat tagcccctaa agaggcaatg atggctgtaa
     1081 tggttgtccc gatattgtca ccaaatagaa ctggcaaagc tccctgtagg tcaattagat
     1141 tgccggcgta gaggttttgt aaaatcccaa tggtagccga agaagcttga attagcaagg
     1201 tcaagccggt accgacaaag acacccaaaa caggattctt acttagctca atcatatagt
     1261 ccttaaagac ctgtaaatcc ttgagtggag ccattgcgcc gctcatgaga ttgagggcaa
     1321 aaaagatacc accgacacca aagaggatgc gtccgatatt attgactgtc cgatttttcg
     1381 taaaaaagag acagacggca ccgataaaga gcataggtag ggcatagtta cctaatttaa
     1441 aaccgatgag aaaggatgtg acagttgtcc caatattagc acccatgaca atcccgatag
     1501 cctgacgtaa ggttaagaga ccggcactga ccaggccgac tgtaataact gttacaccag
     1561 aactagactg aattagagca gtcatcccaa taccaaccag aactccaaag aaaggattac
     1621 tagtatattt gtcaatgtaa aaacgaaggc gatctccagc agcttgttgc aaaccgtctc
     1681 ccatggtctt gatgctatat aagaatagcc ccagaccacc taaaaagtga aataaaattt
     1741 cctgccaatt aatggacatt tctttttcct ccgaaaaata atcgcggaat atctcctatt
     1801 ctattttaaa ggataaaagt aaatctaaca agtgttaatg tcaagtttgt aaaagaaaat
     1861 tataattgat aagtgtatta tttttaagag tttttaacct tattttagat ttgtgcaaac
     1921 agttattgtt ttttgtctaa aaatgtttta ggataaaaat gtgattatca tggttctaga
     1981 gtttgataaa aaactacaga atataaagcg ctttctttaa aacaacaaaa tcaatctttt
     2041 aggaggagaa aatgaagaat ccattttttg aaagacgttg tcgttacagt attcgtaagt
     2101 tatcagtagg agcctgctcg ctgatgattg gtgctgtttt atttgctggt ccagccttgg
     2161 ctgaagaaac tgcagttcct gaaaatagcg gagctaatac agagcttgtt tcaggagaga
     2221 gtgagcattc gaccaatgaa gctgataagc agaatgaagg ggaacatgct agagaaaaca
     2281 agctagaaaa ggcagaagca gctagcgcag ctaaaccaga ggaaaaagca ggtgaggtgg
     2341 ttgcagaaac accatctgca gaagcaaaac ctaagtctga caaggaaaca gaagcaaagc
     2401 ccgaagcaac taaccaaggg gatgagtcta agccagcagc agaagctaat aagactgaaa
     2461 aagaagtcca gccagatgtc cctaaaaata cagaaaaaac attaaaacca aaggaaatca
     2521 aatttaattc ttgggaagaa ttgttaaaat gggaaccagg tgctcgtgaa gatgatgcta
     2581 ttaaccgcgg atctgttgtc ctcgcttcac gtcggacagg tcatttagtc aatgaaaaag
     2641 ctagcaagga agcaaaagtt caagccttat caaacaccaa ttctaaagca aaagaccatg
     2701 cttctgttgg tggagaagag ttcaaggcct atgcttttga ctattggcaa tatctagatt
     2761 caatggtctt ctgggaaggt ctcgtaccaa ctcctgacgt tattgatgca ggtcaccgta
     2821 acggggttcc tgtatacggt acactcttct tcaactggtc taatagtatt gcagatcaag
     2881 aaagatttgc tgaagctttg aagcaagacg cagatggtag cttcccaatt gcccgtaaat
     2941 tggtagacat ggccaagtat tatggctatg atggctattt catcaaccaa gaaacaactg
     3001 gagatttggt taaacctctt ggagaaaaga tgcgccagtt tatgctctat agcaaggaat
     3061 atgctgctaa ggtaaaccat ccaatcaagt attcttggta tgatgccatg acctataact
     3121 atggacgtta ccatcaagat ggtttgggag aatacaacta ccaattcatg caaccagaag
     3181 gagataaggt tccggcagat aacttctttg ctaactttaa ctgggataag gctaaaaatg
     3241 attacactat tgcaactgcc aactggattg gtcgtaatcc ttatgatgta tttgcaggtt
     3301 tggaattgca acagggtggt tcctacaaga caaaggttaa gtggaatgac attttagacg
     3361 aaaatgggaa attgcgcctt tctcttggtt tatttgcccc agataccatt acaagtttag
     3421 gaaaaactgg tgaagattat cataaaaatg aagatatctt ctttacaggt tatcaaggag
     3481 accctactgg tcaaaaacca ggtgacaaag attggtatgg tattgctaac ctagttgcgg
     3541 accgtacgcc agcggtaggt aatactttta ctacttcttt taatacaggt catggtaaaa
     3601 aatggttcgt agatggtaag gtttctaagg attctgagtg gaattatcgt tcagtatcag
     3661 gtgttcttcc aacatggcgc tggtggcaga cttcaacagg ggaaaaactt cgtgcagaat
     3721 atgattttac agatgcctat aatggcggaa attcccttaa attctctggt gatgtagccg
     3781 gtaagacaga tcaggatgtg agactttatt ctactaagtt agaagtaact gagaagacca
     3841 aacttcgtgt tgcccacaag ggaggaaaag gttctaaagt ttatatggca ttctctacaa
     3901 ctccagacta caaattcgat gatgcagatg catggaaaga gctaaccctt tctgacaact
     3961 ggacaaatga agaatttgat cttagctcac tagcgggtaa aaccatctat gcagtcaaac
     4021 tatttttcga gcatgaaggt gctgtaaaag attatcagtt taacctagga caattaacta
     4081 tctcggacaa tcaccaagag ccacaatcgc cgacaagctt ttctgtagtg aaacaatctc
     4141 ttaaaaatgc ccaagaagcg gaagcagttg tgcaatttaa aggcaacaag gatgcagatt
     4201 tctatgaagt ttatgaaaaa gatggagaca gctggaaatt actaactggc tcatcttcta
     4261 caactattta tctaccaaaa gttagccgct cagcaagtgc tcagggtaca actcaagaac
     4321 tgaaggttgt agcagtcggt aaaaatggag ttcgttcaga agctgcaacc acaacctttg
     4381 agtgggggat gactgtccaa gacacaagtc ttccaagacc tctagcagaa aacatcgttc
     4441 caggggctac tgttatcgga agtaccttcc cagatacaga aggtggagaa ggtattgaag
     4501 gtatgttgaa cggtaccatt actagcttgt cagataaatg gtcttcagct cagttgagtg
     4561 gtagtgtgga tattcgtttg accaagccac gtaccgttgt tagatgggtc atggatcatg
     4621 caggggctgg tggtgagtct gttaacgatg gcttgatgaa caccaaagac tttgaccttt
     4681 attataaaga tgcagatggt aagtggaagc tagctaagga agtccgtggc aacaaagcac
     4741 acgtgacaga tatcactctt gataaaccaa tcactgctca agactggcgc ttgaatgttg
     4801 tcacttctga caatggaact ccatggaagg ctattcgtat ctataactgg aaaatgtatg
     4861 aaaagcttga tactgagagt gtcaatattc cgatggccaa ggctgcagcc cgttctctag
     4921 gcaataacaa ggtacaagtt ggctttgcag atgtaccggc tggagcaact attaccgttt
     4981 atgataatcc aaattctcaa actccactcg caaccttgaa gagcgaagtt ggaggagacc
     5041 tagcaagtgc accattggat ttgacaaatc aatctggtct tctttattat cgtacccagt
     5101 tgccaggcaa ggaaattagt aatgtcctag cagtttccgt tccaaaagat gacagaagaa
     5161 tcaagtcagt cagcctagaa acaggaccta agaaaacaag ctacgccgaa ggggaggatt
     5221 tggaccttag aggtggtgtt cttcgagttc agtatgaagg aggaactgag gacgaactca
     5281 ttcgcctaac tcacgcaggt gtatcagtat caggttttga tacgcatcat aagggagaac
     5341 agaatcttac tctccaatat ttgggacaac cagtaaatgc taatttgtca gtgactgtca
     5401 ctggccaaga cgaagcaagt ccgaaaacta ttttgggaat tgaagtaagt caggaaccga
     5461 aaaaagatta cctagttggt gatagcttag acttgtctga aggacgcttt gcagtggctt
     5521 atagcaatga caccatggaa gaacattcct ttactgatga gggagttgaa atttctggtt
     5581 acgatgctca aaagactggt cgtcaaacct tgacgcttcg ttaccaaggt catgaagtca
     5641 actttgatgt tttggtatct ccaaaagcag cattgaacga tgagtacctc aaacagaaat
     5701 tagcagaagt tgaagctgct aagaacaagg tggtctataa ctttgcttca ccagaagtaa
     5761 aagaagcttt cttgaaagca attgaagcgg ccgaacaagt gttgaaagac catgaaacta
     5821 gcacccaaga tcaagtcaat gaccgactta ataaattgac agaagctcat aaagctctga
     5881 atggtcaaga gaaatttaag gaagaaaaga cagaacttga tcgcttaaca ggtgaggttc
     5941 aagaactctt ggctgccaaa ccaaaccatc cttcaggttc tgccctagct ccgcttcttg
     6001 agaaaaacaa ggccttggtt gaaaaagtag atttgagtcc agaagagctt gcaacagcga
     6061 aacagagtct aaaagatctg gttgctttat tgaaagaaga caagccagca gtcttttctg
     6121 atagtaaaac aggtgttgaa gtacacttct caaataaaga gaagactgtc atcaagggtt
     6181 tgaaagtaga gcgtgttcaa gcaagtgctg aagagaagaa atactttgct ggagaagatg
     6241 ctcatgtctt tgaaatagaa ggtttggatg aaaaaggtca agatgttgat ctctcttacg
     6301 cttctattgt gaaaatccca attgaaaaag ataagaaagt taagaaagta tttttcttac
     6361 ctgaaggcaa agaggcagta gaattggctt ttgaacaaac ggatagtcat gttatcttta
     6421 cagcaccaca ctttactcat tatgcctttg tttatgaatc tgctgaaaaa ccacaacctg
     6481 ctaaaccagc accacaaaac aaagtccttc caaaacctac ttatcaaccg gcttctgatc
     6541 aacaaaaggc tcctaaattg gaagttcaag aggaaaaggt tgcctttcat cgtcaagagc
     6601 atgaaaatac tgagatgcta gttggggaac aacgagtcat catacaggga cgagatggac
     6661 tgttaagaca tgtctttgaa gtttatgaaa acggtcagcg tcgtcttcgt tcaacagaag
     6721 tcatccaaga agcgattcca gaaattgttg aaattggaac aaaagtaaaa acagtaccag
     6781 cagtagtagc tacacaggaa aaaccagctc aaaatacagc agttaaatca gaagaagcaa
     6841 gcaaacaatt gccaaataca ggaacagctg atgctaatga agccctaata gcaggcttag
     6901 ccagccttgg tcttgctagt ttagccttga ccttgagacg gaaaagagaa gataaagatt
     6961 aaatatcgaa aaatcttgtg aaatctttcc ttatatttcc aaagtgtgat ataatagttt
     7021 cgaataaaat aaataaagga gtttttgtaa catggcaaaa cttactgtta aagacgttga
     7081 cttgaaaggt aaaaaagtcc tcgttcgtgt tgacttcaac gtaccattga aagatggcgt
     7141 aatcactaac gataaccgta tcacagcagc tcttccaact attaagtaca tcatcgaaca
     7201 aggtggacgt gcaattcttt tctctcacct tggacgtgtg aaagaagaag ctgataaagc
     7261 tggtaaatca cttgctcctg tagcagctga cttggcagca aaacttggtc aagatgttgt
     7321 tttcccaggt gtcactcgtg gtgctgaatt ggaagcggca atcaacgctc ttgaagatgg
     7381 acaagttctc ttggttgaaa acactcgtta cgaagatgtt gacggcaaga aagaatctaa
     7441 aaacgatcct gaacttggta aatactgggc atcacttgga gatggtatct tcgtaaacga
     7501 tgcattcggt acagctcacc gtgcacacgc atctaacgtt ggtatctcag caaacgttga
     7561 aaaagcagtt gctggtttcc ttcttgaaaa cgaaattgcc tacatccaag aagcagttga
     7621 aactccagaa cgtccattcg tggctatcct tggtggttca aaagtttcag acaagatcgg
     7681 tgttatcgaa aacttgcttg aaaaagctga taaagtcctt atcggtggtg ggatgactta
     7741 cacattctac aaagcacaag gtatcgaaat cggtaactca cttgtagaag aagacaaatt
     7801 ggatgttgcg aaagctcttc ttgaaaaagc aaatggtaaa ttgatcttgc cagttgactc
     7861 aaaagaagct aacgcatttg ctggttacac tgaagtgcgt gacactgaag gtgaagcagt
     7921 ttctgaaggc ttccttggtc ttgacatcgg tccaaaatct atcgccaaat ttgacgaagc
     7981 tttgactggt gccaaaacag ttgtatggaa cggacctatg ggtgtatttg aaaacccaga
     8041 tttccaagct ggtacaatcg gtgtgatgga cgctatcgtg aaacaaccag gagttaaatc
     8101 aatcatcggt ggtggtgact cagctgccgc agcgattaac cttggccgtg cagacaagtt
     8161 ctcatggatt agtacgggtg gtggagcatc aatggaactt cttgaaggta aggttcttcc
     8221 aggacttgca gccttgacag aaaaataaga ttttataaac aaatcaaaga agagagggat
     8281 gaaagttcct cttttctttt gcttaaaata aaaacgcttc ctctcaacta ttactcataa
     8341 aaatcaccga tttatgataa aatggaaata gaaagttgag attatgagtt attttaaaaa
     8401 atataaattc gataaatccc agttcaaact tggtatgcga acctttaaaa caggtattgc
     8461 tgtttttcta gttctcttga tttttggctt ttttggctgg aaaggtcttc aaattggtgc
     8521 tttgacagcc gtttttagcc tgagggagag ttttgatgag agtgttcatt ttgggacttc
     8581 gcgtattcta ggaaatagta tcggtggact ctatgccttg gtcttcttct tattaaatac
     8641 ctttttccac gaagcctttt gggtgacctt ggtagttgtt ccaatctgca ccatgttaac
     8701 cattatgaca aatgtagcca tgaataacaa agcaggggtt attggtggtg tagcagctat
     8761 gttaatcatt accctatcaa ttccaagtgg tgagacaatt tcgtacgtgt ttgtgcgtgt
     8821 atcagaaacg tttatgggag tttttgtcgc aattatcgta aattacgata ttgatcgtat
     8881 tcgtctcttt ttagagaaaa aagaaaaata atgttacatt ttataacatt atcaattgac
     8941 gtttgtcttt ttttagacta taatagacag aaagaaggaa attgtaaatg aaggaaaaag
     9001 aatttcgccg aaatatggct gtttttccta tcggcagtgt tatgaagttg accgatctat
     9061 cggcgcgtca gattcgttat tatgaagatc aagagttgat caagcccgat cgaaacgaag
     9121 gaaatcgtcg catgtattcc ttgaatgaca tggatcgtct gcttgaaatc aaagattata
     9181 tctctgaagg ttataatatc gctgccatta agaaaaaata tgctgaacgt gaagcgaaat
     9241 ccaagaaagc ggttagtcag actgaagtac gtcgtgcact tcacaatgaa ctcctccaac
     9301 aggggcgttt tgcttcagta cagtcacctt ttggtcgcgg ttaggcaacc gcaagtagtc
     9361 atagattaag gagaaaactt atgccaatca cagctgcaga tattcgtcgt gaagtcaagg
     9421 aaaaaaatgt tacctttatt cgtcttatgt tctcagatat tttgggaacc atgaaaaacg
     9481 tcgaaattcc tgctacagat gaacagttag ataaggtctt gtcgaacaag gttatgtttg
     9541 atggatcttc tattgaaggt tttgtacgta tcaatgagtc ggatatgtac ttgtacccgg
     9601 acttggatac atggacagtc ttcccttggg gagatgaaaa tggaagtgtt gcaggtctga
     9661 tctgtgatgt ttatacaaca gaaggtgaac catttgcggg tgaccctcgt ggtaatttga
     9721 aacgagctct tcgtcacatg gaagaagttg gattcaaatc cttcaacctt ggtccagagc
     9781 cagaattctt cctatttaag ttggatgaaa atggggaccc aacacttgaa gtgaatgaca
     9841 agggtggcta ctttgatttg gcacctactg accttgcgga caacacacgt cgtgagattg
     9901 tgaatgtctt gaccaaaatg ggatttgaag tagaagcgag tcaccacgag gttgcggttg
     9961 gacagcatga gattgacttt aagtacgatg aagttctccg tgcttgtgat aagattcaaa
    10021 tctttaaact tgttgttaaa accattgctc gcaaacacgg actttacgca acatttatgg
    10081 cgaagccaaa atttggtatt gctggatcag gtatgcactg taatatgtcc ttgtttgatg
    10141 cagaaggaaa taacgccttc tttgatccaa atgatccaaa aggaatgcag ttgtcagaaa
    10201 cagcttacca tttcctaggc ggtttgatca agcatgctta caactatact gtcatcatga
    10261 acccaacagt taactcatac aaacgtttgg ttccaggtta tgaagcgcct gtttacattg
    10321 cttgggctgg tcgtaaccgt tcgccacttg tgcgcgtacc tgcttcacgt ggtatgggaa
    10381 ctcgtcttga gttgcgttca gtggatccaa tggcgaaccc ttacattgct atggctgttc
    10441 ttttggaagt tggtttgtat ggtattgaaa ataaaatcga agcaccagct cctatcgaag
    10501 aaaatatcta catcatgaca gcagaagagc gcaaggaagc tggtattaca gaccttccat
    10561 caactcttca caacgctttg aaagctttga cagaagatga agtggttaaa gctgctctcg
    10621 gagatcacat ctacactagc ttccttgaag ccaaacgaat cgaatgggca agttatgcaa
    10681 ccttcgtttc acaatgggaa attgataatt atttagacct ttactaatac taatatagaa
    10741 gaaagattgc ctgtgggtaa acagtcacac agcagtctaa gccatcaaat acctataacc
    10801 cttaaaatag cgatttcggt cgctatttat ttttcgaaaa atcctcttga ctcttttgcg
    10861 aattagattt atcatcagac gtgtagaaga aaatcaagga gtcactatgg aaaaattcaa
    10921 tttcaaaaac aatatcgggc aagaaaacaa gttacttcaa atcgaaatct acaagtttac
    10981 taacttttgc aagcttcaaa attacacatc tgtaaatatt ttttcgaaag atatatttga
    11041 agccatagta aattgagact agaatagtac actacatctg ctaaaaattt ctagaaatta
    11101 atttaacttt cctaatcgat ttgtttacat cttatttcaa tctactatat tatctcaata
    11161 aatgatgatg gcgactgttt tgtttgtgct tgtcgatttt tgaatcctga tcgagcggaa
    11221 gaatatttct gccgaggttg tcaaggggaa aattctgaag atattgaatt ttatgatgaa
    11281 caattacagg cagaaaaggt ggaggctttg aatattcgat tggaagtaaa aaattgaatt
    11341 atctacaatc tcatcaacaa taaacctatt tcaaccccat tatctatagg cgtattttta
    11401 cgccttttta tatacttgaa gcacata
//
LOCUS       DBEJKC010000058        11379 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.058, whole genome shotgun sequence.
ACCESSION   DBEJKC010000058 DBEJKC010000000
VERSION     DBEJKC010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11379
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.058"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..1661
                     /locus_tag="ACL3G6_001721"
     CDS             <1..1661
                     /locus_tag="ACL3G6_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGR0546207.1"
                     /translation="VYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIVGEYEDAG
                     KSDKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIMQDYGVNL
                     ICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNGGFAPYGY
                     KLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNGKNPLFDA
                     GLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAIVSDEVWQ
                     AAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKDGTKYKDF
                     YYYGCKHRQMIRGHKCTFSKQIIEELLDDAVAEVIVKIVSNPKFASMMQEKINMKVDT
                     SEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYRMYDKIDE
                     LESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISALISEIQVY
                     KEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            1929..2495
                     /locus_tag="ACL3G6_001722"
     CDS             1929..2495
                     /locus_tag="ACL3G6_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546208.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPGENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            2817..3005
                     /locus_tag="ACL3G6_001723"
     CDS             2817..3005
                     /locus_tag="ACL3G6_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HGR0546209.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            3066..3824
                     /locus_tag="ACL3G6_001724"
     CDS             3066..3824
                     /locus_tag="ACL3G6_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGR0546210.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDVRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            3882..4736
                     /locus_tag="ACL3G6_001725"
     CDS             3882..4736
                     /locus_tag="ACL3G6_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HGR0546211.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEATYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            4848..5732
                     /locus_tag="ACL3G6_001726"
     CDS             4848..5732
                     /locus_tag="ACL3G6_001726"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGR0546212.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVIANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            5895..7634
                     /locus_tag="ACL3G6_001727"
                     /pseudo
     CDS             5895..7634
                     /locus_tag="ACL3G6_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
     gene            7909..8364
                     /locus_tag="ACL3G6_001728"
     CDS             7909..8364
                     /locus_tag="ACL3G6_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546213.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            8809..9285
                     /gene="pezA"
                     /locus_tag="ACL3G6_001729"
     CDS             8809..9285
                     /gene="pezA"
                     /locus_tag="ACL3G6_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PezA"
                     /protein_id="HGR0546214.1"
                     /translation="MIGKNIKSLRKTHDLTQHEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            9285..10061
                     /gene="pezT"
                     /locus_tag="ACL3G6_001730"
     CDS             9285..10061
                     /gene="pezT"
                     /locus_tag="ACL3G6_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin PezT"
                     /protein_id="HGR0546215.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQSIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQENGKDSVEYTKDFAGKMVESLV
                     TELSHLGYNLLIEGTLRTIDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYAINPNPARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAAEVLQEYLFGKWSKVEEEMLKVGEERMRDMSKSNGKDA"
     gene            10045..10854
                     /locus_tag="ACL3G6_001731"
     CDS             10045..10854
                     /locus_tag="ACL3G6_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hachiman antiphage defense system protein HamA"
                     /protein_id="HGR0546216.1"
                     /translation="MEKMHSYIKYLTQEDPIITDEGKQIEILHLDIQDDPEIFEDWAK
                     QFRRNYCSDDELAEMIGFMNISPKEYLENFKLPSDSGIGLSTMSGDFGEILVSDYLQY
                     IEEYVVPRTRYDSKVNKNTSTQGSDVLGYKQDSSNVSNDEVVVIEVKSSASDSSSSKA
                     KNKLQEAINHSDKDFERFSTSIVASYLRLKKSNSDQANVVERFLNITDKPFNVIYGAV
                     AVYSNQSYDIDVIKTVVSKNHRDFQKLRLLVIHSNELMKFIRELYSKASEV"
     gene            10851..>11379
                     /locus_tag="ACL3G6_001732"
     CDS             10851..>11379
                     /locus_tag="ACL3G6_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence associated protein"
                     /protein_id="HGR0546217.1"
                     /translation="MIEFGRRSLYFSKLVRSKAKMIEFDIPLESHLPISEDAQKSFLG
                     ALAIVADTARKYFEVYINRKSFNLQLKNQLHNAAEYFDALLVSGLGNSAEYQDYIAIL
                     GTTAYYLCDYNGSSRVMINYISDDIQLLEDCMTLIKVFIDVVTDELFLNHTPIEGKYS
                     SELNTLVESYRNYILS"
BASE COUNT         3999 a         1578 c         2364 g         3438 t
ORIGIN      
        1 aagtatacct ctatacacga gtatctacgt caatacagat agaggggtat tcgttagagg
       61 cacaaaaatc acgaatgaaa gcttttgcta tttacaacga ttatgaaatt gttggagagt
      121 atgaagatgc cgggaagtct gacaagtcta ttgaaggtag aatacagttc aatcgaatga
      181 tggaagatat aaaatctgga aaagatggag tatcttttgt tcttgtgttt aagttatcaa
      241 gatttgcaag aaatgccgct gatgttcttt ctacacttca gataatgcag gattatggag
      301 ttaatcttat ctgcgttgaa gatggcattg attcatctaa agatgctggg aaactaatga
      361 tttctgtttt atcagctgtg gctgaaatag aaagagaaaa catccgtatt caaacaatgg
      421 aaggtcgcat tcaaaaagca agggaaggaa aatggaatgg tggctttgct ccgtatggat
      481 ataaacttga agacggcaag ctgtttataa atgaggaaga ggcagttgca ataagaacga
      541 ttttcgacca gtatgtaaat actacgatag gagccaatgg gatatctaaa tacttagaga
      601 atcatggaat tagaaaaatc ccaagacaga atggtaagaa tcctttgttt gatgcaggtc
      661 ttataagaaa gatattaaag aatcctgtat ataatgggaa aatagcattt ggaagaagaa
      721 ctttagaaaa agttcatggt acaagaaatg aatataagca ggttgaacaa gatgaatatc
      781 taatatctga agggatacat gaagctatag tttccgatga agtttggcaa gctgctcagg
      841 ttaagctaaa atctcaagca aagaaatatg agcatgtgaa taaaggaaaa gatacacgca
      901 cacacttgct ttctggaatt gtaaaatgcc cgatatgtgg agtgggaatg tttgggaaca
      961 agtgtatcaa gaaaaagaaa gatggcacaa agtataaaga tttttattac tatggttgta
     1021 aacataggca gatgataaga ggtcataagt gtacattcag taagcaaatt atagaagaat
     1081 tgttagatga tgctgttgca gaggtgattg tcaagatagt aagtaatccg aaatttgctt
     1141 ctatgatgca agaaaaaatc aacatgaagg tggatacctc tgaaatagaa aaagaaatag
     1201 ataattacca aaaggaattg agaaagagtc attctacaaa gtttaagcta attgaggaaa
     1261 tagataattt agatgttgaa gataagcatt ataagagaag gaaacaggat ttagatgata
     1321 gactatatcg tatgtatgac aaaatagatg aattagaatc atcactaatt gatgcgaaag
     1381 caaagaaaca gactattgaa gctgaaaagc ttacaggaga taacatatat aaggttctga
     1441 tctattttga taagctctat aaagtcatga atgatgtaga gcgtaggcag ttaatttcag
     1501 ctttgatttc tgaaattcaa gtttataaag aaaaacaatc taacggacaa tggctaaaat
     1561 ccattacttt taagctacca attatagaag aaaatctcaa cataggtttg gacaatgatg
     1621 aacaagttga atgtgtaagt ttattagaga aacgtagtta atcctcaaaa ggttccccga
     1681 accttttgag tcccactgac gcatcacgct gaggcggtat cactgcttgt acgagttgaa
     1741 gcatcagcaa agtaaaagta gatgttcagc caatgcgacg aggtgagacc gaaggtcgat
     1801 aaggtgtgtt ctgggtatag gactcgtaaa gtaagtagga aatatgatga gatgatacag
     1861 agagcctgaa ttggtcaggt gacgtgctta tttacattag cctgataatg aaaatggaga
     1921 gattatcgat ggttatattg gaattgtacc aaaatgatta ttctaaagat ttagtagcat
     1981 ttgattccat agaagatggg aaagcctttg tagctcaaat cccgggatac actctggaaa
     2041 cagaagatgg ttttgaagtg gagtatttta atcctaaaaa cataccggat tatatggaaa
     2101 ttatttttaa cggaaatatt gttcctttat ctaaatttat gttcgatcct ggggaaaatg
     2161 taaacattat ttggaaagag atttcaaatt tatccctcaa aaatgataga gtgatcgaag
     2221 gatattcaaa aattgatgca tatgtcgtta acaaccatga agttaaagcc tatgtcgaaa
     2281 caagagaaac gaactatcgt aaagcaaaag acttcttaga aagccgcgga tatgaaatcg
     2341 acagaagctt tttcggaagt gaagacggtg aagcgattct ttacagaaaa aaagggatcg
     2401 aagtttggca tttcttgtgt cacttagacc caatgtttgt agagattgaa gatgtagaag
     2461 gatatgttaa agaagaagtt ggagagattc aatagtcaac caaagttcct tgtgagtata
     2521 tacctttgct agtaaaagag tcaaaacgtt ataacgaagg gggggaagaa aatccttgag
     2581 tgtaagtctt tttcttgttt agagggaaag tattagagta gccgctcata atttatacta
     2641 gatttgataa ctgatttgag acagatttta tttctataaa tattgtgaaa attttttaat
     2701 accaaagatt taaagttact gtgtaaaaaa tcctctccac ttttaaacta atgtattata
     2761 aaagccagtt gacacaagtg ttacacctgt gatagaatta acttgaggtg atgaaaatgg
     2821 caaccgataa aaatagaata atgattagtt tggatgataa aaatctagag aaacttgaaa
     2881 atttagtaga agatgctaga gatagaaggg gaatgcgact aacaaagtcc caggttattg
     2941 aattactcct aaataccgtt gattatttcg atgatattat gggggctatt tactcaaaaa
     3001 aataagagca aaattgctat tatttttaca aattggtgta acactagtga tataggagtg
     3061 atgaaatggt tgtttatatt agacaaagta aattaccaag tgaggtttca attaataaat
     3121 acaatgctca agtaggtgcc tacttacaag gagaagaagt tattttatat caatcttttt
     3181 ctgaaataaa agagttaaca agtgaagata tagttgtaga ttatataatg gagactagag
     3241 cattactaaa aatgatgggc ttaaacgttc cggtttatga ctatcctatt gagcttaaag
     3301 agttttatgg tcgaaagatt tatgctggta ttttaggaga gattgtgaat atacctgata
     3361 attggggaaa atttattaag cctaaagctg gttcaaaagt ctttactgga agagttgtta
     3421 atggaaccca tgatttaata ggtattggtc tacctttcga ctatcctata tggattagtg
     3481 aggttgtaga attcatagct gaatggcgtt gttttgtgtt agatgttcgc gtattagatg
     3541 ttcgacccta tacaggtgat tatcatgcac aatttgatgc aagtgtaatt gatgaagcga
     3601 tatcatgttg gaaagatgcg ccaatagctt atggactaga tatcggtgtt actcgcgatg
     3661 gcagaacact tgttgttgaa gtaaatgatg gttatgcatt gggaaattat ggcctatctc
     3721 ctttaaaatc aatcaatttt catagagcta ggtggaaaga aatggtaaaa ccctattttg
     3781 aaaaaaatga aatttttaaa atccaacagg atgttatttt ctaaaataaa tatggtagat
     3841 aaccaatata aaaagcatca aaatgaacaa ggaggaatct gatgcttgga gcaattattg
     3901 gagatattgt cggttctgtt tacgaatgga acaatatcaa aacaaaggac tttcctttat
     3961 ttcggaagga ctgctttttt acagatgaca cggttatgac ctgtgctgtt gcagaagcaa
     4021 ttatgaatgg tggacaaaaa gacgatttca ttgacgcgat gaagaaatat ggcagaatgt
     4081 atccgaatgc tgattacggt gctcggttta atgcatggct aaacagcgat aaccgtgaac
     4141 cttataatag ctttgggaat ggatcagcta tgcgtatttc tccatgtgct tggatcatgg
     4201 actgtggttt ttatgcgaaa actggtatgt ggccatcatc tagaggactt acgagtcttt
     4261 ctgcagaggt aactcataat catccagaag gtgtcaaagg cgctatggct acagctgatg
     4321 ctatctttct atgtcgtttt tactttggtg gttattgtag agagtacgag caatcaatta
     4381 acgacaatcc tacagagtgt aaaagacgaa ttaaggatta tatagaaaaa gaatacgatt
     4441 acaatctatc tcaaacttta gatgaaatcc gtcctaacta tcgttttaac gaaacatgtc
     4501 aggaaactgt ccctcaagcc attatcgcct ttcttgaaag tagagacttc gaagatgcga
     4561 taagaaatgc catctcactt ggtggcgaca gtgatactct cgcagcaatc acttgtagca
     4621 tagcagaggc aacttacggt attcctgatt ggatcaagga taaggcctat tcttacttgg
     4681 atgaaccctt aaaggatgta gttaggcgat gggaaaatag aataaaagcg tattaatctc
     4741 cagtacgtca gatttctctt ttctgtattt tcattgtata ataggattac atttacttgc
     4801 atacgacgaa atgtaaacat ttctgtttaa aattaaggat aaaatcaatg aaaaaagcaa
     4861 tggtaattat caaccctact tctggtggcg agaaggcttt ggattacaaa gaaaagctgg
     4921 agaataaagc aaaagaatac tttgaatatg ttgaaaccaa aattaccgaa aaagcgctgg
     4981 atgcaacaca ttttgctgaa gaagcttctc gtgagcagta tgatgcagtg gttgtgtttg
     5041 gtggagatgg aactgtcaat gaagtcattt caggtattga tgagagagac tacattccta
     5101 agttagggat tatcccaggc ggtacgggta acctcattac aaaacttttg gaaatcaatc
     5161 aagacatcga tggcgcaatt gacgaactgg attttgattt aaccaataag attgatatcg
     5221 gtaaagcaaa tgacaactat tttggttata tctttagtat cggttctctg cctgaggcga
     5281 ttcacaatgt tgaaatagag gacaaaacaa aattcggtat tttaacctat gctgtaaata
     5341 ccatgaagtc tgtcatgaca gatcaggtct ttaacattaa ggttgagaca gaaaatggaa
     5401 attatgttgg tgaagctagc catgttttgg tccttttgac aaattacttc gctgataaga
     5461 aaatctttga agaaaacaag gacggctatg ccaacatttt gattctgaaa gatgcctcta
     5521 tattctccaa attatccgtc attcctgatt tattaaaagg ggatgttatc gcaaatgata
     5581 atatcgagta tatcaaagcg cgtaatatta aaatctcttc agatagtgaa ttggagtcag
     5641 atgttgacgg agataaatca gataacctac ctgtagaaat caaagtccta gctcagcgag
     5701 tagaagtatt ttcaaaaccg aaagaggatt agtatataga gaaagccttt tttaaggctt
     5761 tttgtatact ttaaaagata gttcctttaa caacggacat tccttgcaaa tagtttacaa
     5821 aaatagtata ctggatttat tgagtttgaa aacgtttgcg taaaatttga atgaatactt
     5881 taggagacaa attgatggaa ttaagtgcta tttaccatgg gcctgagtcg gagtatgcct
     5941 atctttataa ggataagaaa ctccatattc gaattcgaac taagaaaggg gacattgaaa
     6001 gcatcaactt gcactatggg gaccctttta tctttatgga ggagttttat caggatacaa
     6061 aagaaatggt caagataact tctggtacct tatttgacca ttggcaggtt gaagtgtcag
     6121 ttgactttgc acgtatccag tatctctttg agctcagaga tacagaaggt caaaatattt
     6181 tgtatggcga taaagggtgt gtggaaaatt ctctagaaaa tcttcatgca attgggaatg
     6241 gatttaagtt gccttatctt catgagattg atgcctgcaa ggttcctgac ggggtttcaa
     6301 atacggtatg gtatcagata tttcctgaaa gatttgccaa tggcaatgct ctattaaacc
     6361 cagaagggac tttagactgg gattcatctg tcacacctaa gagtgatgat ttctttggtg
     6421 gtgatttaca ggggattatt gatcatatgg attacttgca agacttgggt attactggac
     6481 tatatctttg tcccatcttt gaatctacaa gcaatcacaa gtacaatacg acagattact
     6541 ttgaaattga ccgtcatttt ggagacaagg agacctttcg ggaactggtg gatcaagcgc
     6601 atcatcgtgg catgaaagtc atgctggatg cggtatttaa tcatattggt tcgcaatctc
     6661 ttcaatgaaa aaatgtcgtc aaaaatggtg aacagtctgc ttataaggat tggttccata
     6721 ttcaacaatt cccagtgaca actgaaaagc tagttaataa gagagactta ccctatcatg
     6781 tttttggttt cgaggactat atgcctaagc taaatacagc caatccagag gtcaagaatt
     6841 atcttttaaa ggttgcgact tattggattg aagagtttaa tatcgatgct tggcgtttgg
     6901 atgtggctaa tgagattgac catcagttct ggaaggattt tcgtaaggca gttttagcta
     6961 aaaatcctga tctttatatc ctaggagaag tctggcatac atctcagcct tggctaaatg
     7021 gagatgagtt ccatgccgtc atgaattatc ctttatctga tagtatcaag gactatttct
     7081 tacgaggaat taagaataca gaccagttca tcgatgaaat caatggagag tctatgtatt
     7141 acaagcagca gatttcagag gtcatgttta atctcttgga ttcacatgat acagagcgaa
     7201 tcctgtggac ggccaatgaa gatgttcaac tggttaaatc agccttagcc tttctctttt
     7261 tacaaaaagg aacaccgtgc atttattacg gaaccgagct agccttgact ggaggaccag
     7321 atccagattg tcgtcgttgt atgccttggg aacgtgtatc aagtgacaat gatatgctga
     7381 actttatgaa gaggctgatt aagattcgga aatacgcgtc agtaatcatt tcgcatggca
     7441 agtatagcct tcaagaaatc aaatctgatc tagtagctct ggaatggaaa tacgaaggac
     7501 ggatcctcaa agcaatattc aaccaatcaa cagaagatta tcttttagag aaagaagcag
     7561 tagtactagc aagcaattgc caagaattgg agaatcagct tgtcatctct ccagatggat
     7621 ttgtgatttt ctaaaaacta gttgatgaag attatggtac atttcatatc ttatatagta
     7681 taataaggct agttactaaa cttgtaaagg agaacttaaa tgaattgtag aggacatgaa
     7741 acaagacaaa gaattgttag agattttgaa gtttagccta aagcacatat taagctgtta
     7801 gcaaatcaac aaaaacatag tgatgcagga gcaactattg aagatgaata ttatgtattt
     7861 atcgctgaga gtaaaattga tggcaagaag gaagttattc agtgttgcat gggtgcggca
     7921 agggattttt tagaactaat taatcacaaa gggctacctc tttttaatcc gcttgtaggt
     7981 gattctcatg taaataatag acaagaatat gacaatacag ggagtggaaa tttacaacct
     8041 gaaaagtgga atgaaactgc aaagcagctt tataatgtta taatgtggtt gattatttta
     8101 tggaatgcta agccggatac acctttattt aattttaaag acgaagtaat taagtataaa
     8161 acatatgagc cttttgaaag cagtataaaa agagtaaata ctactataaa gaatggtagt
     8221 aaagggaaaa ctctgactga gatgattaat ggctacagag cggataacga tattagagat
     8281 gaaatttgta actttaatat tctgaaaaat aaaattcgtg atatgaaaga ccaacaagga
     8341 aatacaatgg aatcttactt ttagttattg ttgaattttg ggtattctat aaaatatcct
     8401 aattgagatt taaatagtag actatacaat atagttaaaa tatcagtaaa aacaacactt
     8461 tattgaggta ttggatacgc tttgctaata gcctaataat cacatgtgga gtgttgctac
     8521 aacgaaaaag gtgataatcc ttgatttcaa gctattttat aagcattttg tctttgtaga
     8581 taaaggcaat tttgacaata aaaatcctaa aaggtgaatc gttatagatg tatttgtaga
     8641 tatcgtttgc gcatcgaaaa aattaataca agaataaata tttatggctc tttaggtgac
     8701 ttttatagaa gtaaagttta ggatagaaaa acagtcaata acgcaccatt tttggtgcgt
     8761 tatgcttttt tatgctataa tggatttata aaaataaagg agtttgccat gattggaaaa
     8821 aacataaaat ccttacgtaa aacacatgac ttaacacaac acgaatttgc acgaattata
     8881 ggaatttctc gaaatagctt gagtcgttat gaaaatggaa ctagttcagt ctctacggaa
     8941 ttaattgaca tcatttgtca gaagtttaat gtatcttatg tcgatattgt aggagaagat
     9001 aaaatgctca atcctgttga agattatgaa ttgactttga aaattgaaat tgtgaaagaa
     9061 agaggtgcta atctattatc tcgactctat cgttatcaag atagtcaggg aattagcatt
     9121 gatgatgaat ctaatccttg gattttaatg agtgatgatc tatctgactt gattcagaca
     9181 aatatctatt tagtagaaaa ttttgatgaa atagagagat atagcggcta tttggatgga
     9241 attgaacgta tgttagagat atctgaaaag cggatggtag cttaatggaa atccaagatt
     9301 atactgatag tgaattcaaa catgctttag caaggaatct tcgttcactg acaagaggaa
     9361 aaaagtccag taaacaatct atagcgattt tgcttggagg tcaaagtggt gccggtaaga
     9421 ctacaattca tcgtattaaa cagaaagaat ttcaaggaaa tattgttatc atagatggtg
     9481 atagttttcg ttctcagcat ccacactatt tagaactgca gcaagaaaat ggcaaagata
     9541 gcgttgaata caccaaagat tttgcaggga aaatggtaga gtctttagta accgaattga
     9601 gtcatttggg atacaatctt ttgatagagg gaactttacg aactattgat gttccaaaga
     9661 aaacagcaca actattaaaa aataaggggt atgaggtaca attagcctta attgcaacca
     9721 agcccgaatt gtcctatctg agcaccctta tccgatacga agaactgtat gctatcaatc
     9781 caaatccagc acgcgcaact ccaaaagaac atcatgattt cattgtaaat catctagttg
     9841 ataatacacg acaattggaa gaactagcta tttttgaaag aattcaaatt taccaacgag
     9901 atagaagttg tgtatatgat tcaaaagaaa atacaacttc agcagcagaa gtgctacaag
     9961 aatacctctt cggaaaatgg agcaaggtag aggaagagat gttgaaggtg ggagaagaac
    10021 ggatgaggga tatgagtaaa agtaatggaa aagatgcata gttatataaa gtatctaact
    10081 caagaagatc ctattattac tgatgaaggt aagcagattg agattcttca cttagatatt
    10141 caagatgacc cagaaatttt tgaagattgg gcaaaacaat tcagaagaaa ttattgttct
    10201 gatgatgaac ttgctgaaat gataggtttt atgaatatct cccctaaaga gtatcttgaa
    10261 aattttaaat taccctcgga tagtggtatt ggcctttcaa cgatgtcagg agattttgga
    10321 gaaatattag tatctgatta tcttcagtat attgaagaat atgtggttcc taggactcgt
    10381 tatgatagta aagtcaataa aaatacttca actcaaggaa gtgatgttct aggatataag
    10441 caagattctt cgaatgtgtc gaatgatgag gttgtagtta ttgaagtaaa atcatctgca
    10501 tcagattcta gtagctctaa agcgaaaaat aagcttcaag aagctattaa tcattctgat
    10561 aaagattttg aacgattttc aacctcaatt gtagccagct atttgaggtt aaagaaatct
    10621 aatagtgatc aagcaaatgt agtagaaaga tttttaaaca taacggataa accgtttaat
    10681 gtaatctatg gagctgttgc agtctactcc aatcaatcat atgatattga tgttatcaag
    10741 acagtagttt caaaaaatca cagagatttt cagaaattac gactattggt cattcattct
    10801 aatgaattaa tgaaatttat tagagaactc tattcgaaag cgagtgaggt atgatagaat
    10861 ttgggagaag gtcattatat ttttcaaaat tagtgcgttc aaaggcaaag atgattgaat
    10921 ttgatattcc tttagaaagt catttaccaa tttcagagga tgctcaaaaa tcgtttcttg
    10981 gggcactagc aattgttgca gatactgcta ggaagtattt tgaagtttat atcaatcgta
    11041 agagttttaa tttacaatta aaaaatcaat tacacaatgc tgctgaatat tttgatgcat
    11101 tgctggtgtc aggattagga aattcagctg aatatcaaga ctatattgca atattgggta
    11161 ccacagctta ttatctatgc gattataatg gtagttcgag agttatgatt aactatatat
    11221 cggatgatat ccagttatta gaagactgta tgactcttat aaaagtattt attgacgttg
    11281 taacggatga actctttttg aatcatacgc caatagaagg taaatactct agtgagttaa
    11341 atactctagt tgaatcatat agaaattata ttttatcaa
//
LOCUS       DBEJKC010000059        10947 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.059, whole genome shotgun sequence.
ACCESSION   DBEJKC010000059 DBEJKC010000000
VERSION     DBEJKC010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10947
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.059"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(420..1613)
                     /locus_tag="ACL3G6_001733"
     CDS             complement(420..1613)
                     /locus_tag="ACL3G6_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HGR0546218.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            complement(1751..3193)
                     /gene="gtfA"
                     /locus_tag="ACL3G6_001734"
     CDS             complement(1751..3193)
                     /gene="gtfA"
                     /locus_tag="ACL3G6_001734"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HGR0546219.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTMLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            complement(3493..4326)
                     /locus_tag="ACL3G6_001735"
     CDS             complement(3493..4326)
                     /locus_tag="ACL3G6_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0546220.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            complement(4340..5206)
                     /locus_tag="ACL3G6_001736"
     CDS             complement(4340..5206)
                     /locus_tag="ACL3G6_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0546221.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAAFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            complement(5220..6479)
                     /locus_tag="ACL3G6_001737"
     CDS             complement(5220..6479)
                     /locus_tag="ACL3G6_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR0546222.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            complement(6571..8733)
                     /locus_tag="ACL3G6_001738"
     CDS             complement(6571..8733)
                     /locus_tag="ACL3G6_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGR0546223.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHITLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            8841..9701
                     /locus_tag="ACL3G6_001739"
     CDS             8841..9701
                     /locus_tag="ACL3G6_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGR0546224.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIS
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQSPSHTRKEYS
                     QYQLVRKATL"
     gene            9698..10633
                     /gene="birA"
                     /locus_tag="ACL3G6_001740"
     CDS             9698..10633
                     /gene="birA"
                     /locus_tag="ACL3G6_001740"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HGR0546225.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEINSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(10759..10846)
                     /locus_tag="ACL3G6_001741"
     tRNA            complement(10759..10846)
                     /locus_tag="ACL3G6_001741"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10810..10812),aa:Ser,seq:gct)
     gene            complement(10853..10926)
                     /locus_tag="ACL3G6_001742"
     tRNA            complement(10853..10926)
                     /locus_tag="ACL3G6_001742"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10890..10892),aa:Ile,seq:gat)
BASE COUNT         3533 a         2337 c         1894 g         3183 t
ORIGIN      
        1 taacaatatt gtagaagtat cattctagta ttcaagattc agtttactat gtcttttcac
       61 accaacctta ttccgaattc aattactttc gtgatttaca catatagatt aagactatct
      121 tttatacttt aaaatttctc gctaccttgt ccactatatg ctcctcgcta tcacgtttct
      181 attcatagcc tacgatttca ctattgcttt ctctgacaat tcttatttcc tgcgtcagac
      241 ttaaaacgat ctatccccag accattttaa tccgctacct cacgatagtc aggcttgggg
      301 agcgctattg tattcaccgg tagtggatcc ctacagagga cttacacctc agatgcacga
      361 catgcccatc gtataaaaaa atctcctacc caaggtagaa gatttcaaac ttataaaact
      421 taatccgtca tgtccgatac caacattcga tgctccaatg gaatactgca cataactagc
      481 aagaaaataa agcctgactg aatccagaag agagccaagt caaaaattcc gtgcacagca
      541 accactgtaa ggaaagatag ataaaggccg ataatcggac gtttccccga ctcctgactc
      601 atatccatca tcaagcgaac aggagcaaca gaagacaaaa ctaataaaat ggtacccaca
      661 attccgtaac tcagaatcgt atcaatataa agactgtggg catgttcatg ataaggagca
      721 tgtatccgag gataagagtg catataggtc aatggccctt caccccaaaa aggattttgc
      781 ttaaacaagg ccatcccagc atcccagata gaaatgcgtt cttccataga agagtctaaa
      841 gtacccattc gaactcccaa atcactagaa aagaggaaac tcaaaccaat cgcgaagacc
      901 ccaatactaa gccaaaaggc cttccagttt ttaatagtcg taaagagata gataattgct
      961 ccagcgataa tagcaggaaa ggcagttcga ttttgagtaa agttcaaacc aaagagatta
     1021 acaaagcctg caatcacaca gaatactttc aaccaattca acttggtcgt tgtaaacaga
     1081 tagaaagcaa tcataataca gaaacaacaa ataattccat aataattagg attaaagaag
     1141 gtcacttctg cccggttctg atgccacacc tgcatattgg gtgaaagaaa agcatagtta
     1201 aatttcttca caatttggaa atgttctaaa ctggcaaaag cagctgacaa gacactacca
     1261 aacaagacga actgcaaaat caatcgaaag aatttatggg ataaaatcga ctgatagtgc
     1321 aaaaagaaaa tagtaaatag aaacattcct actgaagcca caagacccat ccaattttgt
     1381 gcaagaatgg atataacagt actatagcta agaaaaagaa gcagcatcgg atgctccccc
     1441 attttctgaa gaatactttt catgtctcct gtaaaaatca aactgataat atataaacag
     1501 agtacaacta caaaaagata aaagggtaaa aagatactta ggataattcc caataaaatc
     1561 agctctttac tagacaaccc cttcagcttt tcaataaagc ctattgattt caaaatgaat
     1621 cctttctctc caaatcagct gattcagata atagtaagct atcctatatt gtaccacttt
     1681 tttagcaatt tgaaaacaaa ggaaacgttt tccaaaataa aaaccctatt ttatccacca
     1741 tatcaaggct tcaaaatgat acttcaactc cattctcaat tacccgataa gtctgatttt
     1801 gcaaatcaat ttctactact gctgttacgg acttatcttt attttgacgt ttgattacaa
     1861 tgctgtgagc tgttggtgtc tctatctcag tagtcccttc tagatcaaag gcttctgaac
     1921 ggttacggaa agaaaataga ttgagaaggg ccttcacaac aggtcgttgc acttcttttg
     1981 ctatttcctc gttgctatag taatgacgat taatatttcg accttcttta gtttcttcta
     2041 ataatttcaa gtcattcttg cctgctaata gacccacata gtaaacctga ggaatacctg
     2101 gggcaaaagc ttgaattaga cgagcgagaa aatacttgac atcatcatct ccaagcgctg
     2161 aatagtaggt tgaattgatt tggtagatat ctaagttgtt atactcggca ctagagtact
     2221 tacgtttgac attggctcca accttataga gttcatttga agcatagtca atctcctcat
     2281 cggtcaggat atccttgaca tctactactc caatcccatc atgggtatct agcatcgtaa
     2341 attgcttcat cgggctcatc tttaaccact tagccaaacg ctctgttctg gaactgtaaa
     2401 gagtataaag tgtcaccatt ggaagagcaa aatcataaac atagtaatca tggtctgcta
     2461 ttttaaactg aatcgaatag tgttcatgaa tctcaggtaa aagctctgtc ccatactcag
     2521 cagcgatatc tcgaactttg tccaataaat cccaaatatc tggttccaca aagaaatcat
     2581 tagtatccaa tttcttcact gcataagcaa aggcatctag acgaatcaaa tcacacccat
     2641 tacttgccaa gtgctgaatg gtcttacgga taaattccat agttacttct ttggtcacat
     2701 caagatcaat ctgctcctca ccaaaggtat tccacaaatg ttccactgaa ccatcttcaa
     2761 acacaatctc ttgctttggt gcacgatcct tacgcttgta aattaaatct acatcagact
     2821 gtgtcggacg gttttctggc caaaacttat cccagtttaa aaagagagct ttaaattcac
     2881 tggcttcatg tttttcttga tagtccttat aatacttgga ttgacgagaa atatgattaa
     2941 tcataaaatc aaacataaga taatatttct cacctaaacg cttaacatcc tcccaatcac
     3001 caaaagctga gtccacttcg tcgtagtcaa ctggcgcaaa tccacgatca cctgttgatg
     3061 ggaaaaatgg taaaaggtga actcctccaa tagcatctcc aaaatgctct tccaaattat
     3121 catataagtc tttaagatta tttccaaggc tatcagaata ggtaatcaac atggttttat
     3181 tttgaattgg catcattact ctcctttttc taattgaagc caagtctcat atgatctggc
     3241 ttcataaata aaattcattt taaatctcta tttatcatca aactcgtact aatatagact
     3301 gtgataaaca aagtactact ttcttgtttt ctgcatagaa ttatcaacaa gctaaactct
     3361 tcctctgtgt caaagactat agattccatg agctcttcga aaatctcttc aaaccacgtc
     3421 agcttcacct tgccgtactc aagtacagcc tgcggctagc ttcctagttt gctctttgat
     3481 tttcattgag tattacttca ctgccccgtt gctcattcct gaaatgatat ggcgttggaa
     3541 gaagagatag acaatggtga tactgataat gccgaccacg taagaggcaa agcttggtcc
     3601 gtagtcgttg aaatattggc ctgcgtagtt gtattggaac aaaggcagag tccacatttt
     3661 ggaatcccgg ttcaagacaa ggagtggcaa catgaagtca ttccagaacc aaagggcatt
     3721 gataatcatg gttgtcgcat gcatcggttt catcattggg aagatgatgc ggaaataggt
     3781 tgtaaattga ttagccccat cgatctctgc tgcttcatcc agactttctg gaatcgagat
     3841 tttgatatag ccaacataga gaaagagggt ctgtggaatc gcataggtca agtagagcaa
     3901 gatcaaacca aaggtattag ccaaaccgag tttactcatc ataaccgtaa tcggaatcat
     3961 gatgacttgg aaaggtacga agattccgag gattaagagg gtatacatga tggtaaaggc
     4021 ttttctttta ctcatattgc gagcgatgga gtaggctgcc atagggataa agatcattac
     4081 tgcaagtaaa gacaagacag tgatgacgac agagttccaa taatagcctc caatcccatc
     4141 agctaagaga cggctaaagt tgtcccatgt gaagttggtt ggaaagccaa agaaattatc
     4201 tacaatatcc ttagtgggtt tgaaggaact aaagagggta gcaaggagcg gcactaaaat
     4261 cagaaccgat cctagaatca atagaatgta tttgccaatc agggcttttc tttcatcttg
     4321 tttcatcatg cttctcctct taaatttcaa atttcttaga tactctcaat tggatgatcg
     4381 aaatcactac aattaagagg aacaagatta cggcaatggc attggcataa ccgaattggt
     4441 tgtttttaaa ggcatagtta taaaccaaga gcccaagtga ggttgtggca ttgtttggac
     4501 caccaccggt catggcaaag acttggtcaa aggcagtcag cccacctttt agggctagga
     4561 taaagaccat agagacactt ggtagcaagt aaggcaattc aatgttccag aaaacttgct
     4621 tgctagtcgc accatcaatc cttgctgcct ctgtaatctc agttggaata gattgcaaac
     4681 cagctaggaa gatgatgatg ggcatagcca ccccttgcca aagaaggaca aaggcagccg
     4741 caaagattgc tccccactta gtccctaaaa gactggtttg gagaaattca atatgaaggg
     4801 cattcccaat cgctggaaga ccgtagttga agacttgctt gaagatcaaa gccactgtca
     4861 aaccagataa aacagctggg aagaagaacc aagcacggaa gaaggtttgg cctttgattt
     4921 tagagttcaa gacacgcgca atgaagatcc cgagtgcaat ctcaccaacc accatggcaa
     4981 tcgtaatgat tgcggtaaag ccaatcgcat tcatgaattt tggatccatg aagaggagct
     5041 taaagttgtt taagccgaca aatttgtagt tataagtcaa tcctgtccag ttggtaaaac
     5101 tgtaaaaggc tccttgaaac atcggcacat agaagaaaat tgcttgtaac aagaggggga
     5161 tgaccacaaa agcccatgcc caatattttt gtaatacttt tttcatagtc tctctactcc
     5221 taatccacat ccgctttcat cgggttaaag aaggcattca aatcattgac catgccttgt
     5281 ttatcaccgg tcaagacata gttcatggtc aaggtatgga agtctgcttc actggtccag
     5341 tattgttgca accagaccaa gtgacgatcc gtaaaggcat attcggtcat accagcaagc
     5401 ggtgaatctt ctcctgcttg tttgacccct tcgatcgctg ttggagatcc gtccacatcg
     5461 tagtattttt gcatgacttc tggacgggtc atatattcca caaaggcatt ggcttctttt
     5521 ggatgtttgg tggtggctga gatagaccat gccaagtctc ccgcaccaac ggttaagctt
     5581 tgtccttttt cttttcctgg aatcatgaag gtcccaatct taaagttcgg tttttgttca
     5641 ttaatcgctg tgatcgccca agacccattt ggtgtcatga ggacatcccc acgtgcgaag
     5701 gctccgataa catcggtata gccagcacct tcccagttct tttgcttaga gccattgatg
     5761 cgaaggatgt ccatgacctt gatatcatct ttcataatcg gatccgacaa tttaatggca
     5821 tttggttgag aataacgaag gtattgattt gcttcttttc ctccacctgt tgctgtcgca
     5881 aaggctaatt gattgtaacc attgagtgtc caagcatctg cacctgcaat tccaaatggt
     5941 gtttgtcctt tagcaacgat atctttgact aactgttcaa attcatccca ggtttcagga
     6001 accttcaagc ccagttcttc gaatttatct ttgttgtagt aaattccata agcattagct
     6061 gtaaaaggaa cgttgtaaac tttttcgttt acagcatatt tttcagcgta gccatttttc
     6121 acgcgtttca ggtagtcttt gttgctcaaa tcttcaaaaa cacctgcttt tgcccattct
     6181 tgcagttcga tggactgtgg gtaaatattg accacatcag gcacatctcc tgcgagaacg
     6241 cgtgtcttca atacttcacc agcatttggt acattgacga ctttgacctt gatcttaggg
     6301 ttttccttct caaaatcacg agtgatttct tccaaggttt tggtcatttc ttttttctgg
     6361 ttgaaatact cgatggtcac tgtgccatcc gcagatttac catagttgga gcaagcgccg
     6421 agcccaaaca aagctaaacc tgtagttgca agaagtccga tttttttata ccattccatt
     6481 agaaagcctc ctttataaat ttatacaccc ttattgaact gcaccccaaa agttagacag
     6541 aataaatcta acttttgggg tcagtacata tcatagtttt ctaaaaatat actgtctact
     6601 caaaaaatct ccttgggata agataacagt taagcccgca tacattagtt ctgcacctga
     6661 gtaaacttcg ccattttcct gtaatttata tagtccctct tcatccaaat cttttaattt
     6721 taaagttgtt tccatggtct ctacaacaga taaaacgcga acgtaggtta caatcgtttg
     6781 atttccgtaa ttaaattgta cagctgcttc attggatgca gtatcaggat taattagtct
     6841 atactgctgt cctaactgaa ctactggtcg taattcttta tacaagttca cctgattagc
     6901 aatcgtagct ttctcttcat ctgataaatt tgtcaaatca agctcatagc ccaaatttcc
     6961 catcattgct acatggccac gtgtttctaa tggtgtcatt cgtcccatct gatgattcgg
     7021 tactgctgac acatgagccc ccatagaaat ggttggatag agataggatg aaccgtattg
     7081 aattggtaaa cgtgcaatgg catcagtatt atcactagcc cagacttgtg ggaaatagcg
     7141 tatcatacca agatcatttc gtccaccacc accagagcag gactcaaaga gaatatggct
     7201 gtgcttctct gtcagataag aaacgagttc gtaaagtccc agcatgtact gatgagattg
     7261 catctgtgtc tctagataag ttaatccatt ccctagctta gtgatattgc ggttcatatc
     7321 ccatttaatg taatcaatct catgataaga taggagttga tctaagacac ttttcaagta
     7381 ttctactacc tgaggattgg caagattaag tactaattga ttccgagaat aagtatgctc
     7441 ataatcagga acctgaatag cccagtcagg atgttgacga tacaaatcac tatctacaga
     7501 aatcatttcg ggttctaacc aaagtccaaa ctgcaaacct ctttcatgga tagctgaaat
     7561 cagactttct agacttccac ccagtttttc ctcattaaca acccaatcac ctaaagcacg
     7621 attatcatca aaacgattgc caaaccaacc atcatctaat acaaaaagtt caatgccaac
     7681 tttcttagct tcatctgcta actctaacag tttttctctc tgaaagtcaa agtaagtagc
     7741 ttcccagtta ttgattagaa ttggacgttc ttttttagaa aattcactta gagtaatgtg
     7801 cttcagtaca aaattctgac tttcatgact aataccagtt aatccctgat ctgaatgagt
     7861 cactaaagct accggtgttt caaagtattc ctcaggggct aacttccaag aaaagttttc
     7921 tggattaatg ccaatagcca cccgaacttc attcaattga tttttttgaa caaaagcttc
     7981 aaagttgcca ctatacatta gttgaatagc aaacacattc ccagcatcct ctgtgactcc
     8041 ttgttcgcat agtagaagag ctggtgtttg agcatgacca gaagcacctc ggtttgaact
     8101 aatcgaaaag attccttgtt ctacctgttg acgtctaaca gtcttttcac gagcataagc
     8161 accctgcaga gttactattt cgtaatctgc agctggaaaa tcagccataa aagaaaaatc
     8221 tttatggatg acaacttcct gattactatt attatctaat ttactgtagc tagcaatagt
     8281 cgcatcatta ttaaaagtag tataatacaa agtcagacta agttgagcct tagaatcttc
     8341 taacattaag acaagagtct ctgtatcgtc catgctatgt ggagaaggta agccctgtgg
     8401 accattctga ccttttaaaa tctttgcttc tacaaatcga aagtctgtta cttcagttac
     8461 actatgctga acctgtatag ttggtttcct aaaatctcct aagccatgtt gtccaaaaat
     8521 ctgtcgctga gtatctaaac taaaggttcg attagtagcc gttggatttc ctgaaaaggc
     8581 atggtctcgt tcataaacac tattggaacc tttatagttc ttaatagtct ttcctaaatg
     8641 tttcaaaagt aagtagccat ttcgattttc aataatcaaa cttagatttt tactctcaac
     8701 ataaaataga ttattctcta tcctaactcc catttacttc acctcatcac tttattgatt
     8761 atattttatc acctgaaatc gctttccaaa atagaaaaat gtctcaagaa tatggtaaaa
     8821 tgttaggtag gaggtagcac atgctagttt tttcagaata ccagactgga acaattgacc
     8881 ttgccctaag cttttatgga tatgaggaat gcacacctaa ttactctttt ggtccagcca
     8941 ttcgtgatac atacgtccta cattacatta gtaaaggaca aggaaaattt cattacaagg
     9001 gtaaaattgt tgatttaaaa gaaggagatt tctttctatt aaaaccagag gaactaacct
     9061 tttatcaagc agatagtaaa gaaccttggg cctactactg gttaggaatc actggaggga
     9121 aatcccctga ttattttgct ctttctcaaa tttctgatca atcctatctc atccaatctg
     9181 aaacttgtca tacccagact actgcaaaac tcatctcaga cattgtccgc ttcgctcaga
     9241 ttacaaaatc aagtgaatta gctcaactcc atatcatggg acaacttcat gaactgatgt
     9301 ttcatctggg aactattgct cccaatcaga aaaaaaagaa tatttcatca acccaccaac
     9361 tctatcttga atgcaaacga ttaattgata gccactatcc tcaatcactt acaattcaag
     9421 atttagcaaa agaactatcc gttcacagaa gctacttatc aagcgtattc aaagaattta
     9481 ataccttatc acccaaagaa tacctactct acgttcgaat gcaccgagct agacaacttc
     9541 tcgaaaatac ccaagagtcc atcaaggtaa ttgcatactc ggtaggtttt tcagatccac
     9601 tccatttttc gaaagcttat aaacaatact ttaatcagtc tccaagtcat acaagaaaag
     9661 aatactctca ataccaacta gtgagaaagg caacattatg aaatcctacc aagctgtcta
     9721 ccaaatccta tctaaagaaa ccgactatat cagcggagaa aaaatcgcag aaaaactatc
     9781 cctaagccga acatcaattt ggaaagctat caagcgacta gaacaagaag gcattgaaat
     9841 taatagtatc aaaaatagag gatataaact aatgaatggt gaccttattc ttccagagat
     9901 tctagaagaa aatcttccaa ttaaagtcag ctttaaaccc gaaacaaaat caacacaact
     9961 agatgcaaaa gaagcaattg atttaggcca tgaagcaaat actctctatc tagcttccta
    10021 tcaaacagca ggccgaggcc gttttcaacg ttccttctac tcaccacaag gtggaattta
    10081 tatgacactc catcttaaac caaatctccc ctatgacaaa ttaccatcct acacactact
    10141 tgtagctgga gctgtctaca aagccattaa gaacctaact ttaatagatg tcgatataaa
    10201 atgggtcaat gatatctatc taaacaatca taaaattgga ggaatcctta ctgaagcaat
    10261 gacctctgta gaaactggct tagtcacaga tatcattatt ggagtaggta tcaatttcac
    10321 tattaaagac ttccctcagg aattaaaaga aaaagctgcc agcttattta aagctacagc
    10381 tcctataaca aggaatgaat tgatcataga aatctggcgt gctttcttcg aaacaccagc
    10441 agaagagcta ttatacctat acaaaaaaca gtcattcatt ctaggaaaag aagtcacttt
    10501 cacactagag caaaaagact acaagggact tgctaaagac atctcagaaa atggaaaact
    10561 tttagttcaa tgtgataacg gaaaagaaat ctggctaaat agtggcgaaa tttctctcaa
    10621 tagttggaag taaaataaca caattataat ataaacgata taaaaataac ttcagattag
    10681 taattcaatt aagttttacg gatctgaagt tttattgtct ctaaaaacaa aaaagagagt
    10741 tacaaactct cattaaaacg gagaataagg gattcgaacc cttgcgccag ttacccgacc
    10801 taacgattta gcaaaccgtc ctcttcagcc tcttgagtaa ttctccaatt aatgggcacg
    10861 agtggactcg aaccaccgac ctcacgctta tcaggcgtgc gctctaacca cctgagctac
    10921 gcgcccaagt taaaaaactt ggtaatt
//
LOCUS       DBEJKC010000060        10673 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.060, whole genome shotgun sequence.
ACCESSION   DBEJKC010000060 DBEJKC010000000
VERSION     DBEJKC010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10673
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.060"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            31..351
                     /locus_tag="ACL3G6_001743"
                     /pseudo
     CDS             31..351
                     /locus_tag="ACL3G6_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            472..1416
                     /gene="manA"
                     /locus_tag="ACL3G6_001744"
     CDS             472..1416
                     /gene="manA"
                     /locus_tag="ACL3G6_001744"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HGR0546226.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(1437..2705)
                     /locus_tag="ACL3G6_001745"
     CDS             complement(1437..2705)
                     /locus_tag="ACL3G6_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HGR0546227.1"
                     /translation="MTAANGDGGFLLIFLISTILIGFPLLLAEFALGRSAGVSAIKTF
                     GKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFGKLFQLGGTGDYAQLF
                     TSIISNPAIALGAQAAFILLNIFIVSRGVQKGIERASKVMMPLLFIIFVVIIGRSLSL
                     PNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLTYASYLDKKTNLVQSG
                     ISIVAMNISISIMAGLAIFQARSPFNIQSEGGPSLLFIVLPQLFDKMPFGTIFYVLFL
                     LLFLFAPVTFSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIPSALSYGVMADV
                     HIFGKTFFDAMDFLVSNLLMPFGALCLSLFTGYIFKKALVMEELHLDERAWKQVLFQV
                     WLFLLRFFVSSFQSSSWSSSPNLCNQKGLE"
     gene            complement(2702..2923)
                     /locus_tag="ACL3G6_001746"
     CDS             complement(2702..2923)
                     /locus_tag="ACL3G6_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HGR0546228.1"
                     /translation="MIFLTDLRKHDRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGWPSGLVPFGSFPT"
     gene            3028..3777
                     /locus_tag="ACL3G6_001747"
     CDS             3028..3777
                     /locus_tag="ACL3G6_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HGR0546229.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            complement(3797..4252)
                     /locus_tag="ACL3G6_001748"
     CDS             complement(3797..4252)
                     /locus_tag="ACL3G6_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGR0546230.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4272..5447)
                     /locus_tag="ACL3G6_001749"
     CDS             complement(4272..5447)
                     /locus_tag="ACL3G6_001749"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR0546231.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDNQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5506..6351)
                     /locus_tag="ACL3G6_001750"
     CDS             complement(5506..6351)
                     /locus_tag="ACL3G6_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR0546232.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6476..7033
                     /locus_tag="ACL3G6_001751"
     CDS             6476..7033
                     /locus_tag="ACL3G6_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGR0546233.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7052..7519
                     /locus_tag="ACL3G6_001752"
     CDS             7052..7519
                     /locus_tag="ACL3G6_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HGR0546234.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7608..8237
                     /gene="upp"
                     /locus_tag="ACL3G6_001753"
     CDS             7608..8237
                     /gene="upp"
                     /locus_tag="ACL3G6_001753"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HGR0546235.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8411..9001
                     /gene="clpP"
                     /locus_tag="ACL3G6_001754"
     CDS             8411..9001
                     /gene="clpP"
                     /locus_tag="ACL3G6_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HGR0546236.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9080..9328
                     /locus_tag="ACL3G6_001755"
     CDS             9080..9328
                     /locus_tag="ACL3G6_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HGR0546237.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9430..10590
                     /locus_tag="ACL3G6_001756"
     CDS             9430..10590
                     /locus_tag="ACL3G6_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0546238.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDSLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
BASE COUNT         3392 a         2120 c         2278 g         2883 t
ORIGIN      
        1 tataatgctt tttgatttta gtttagtatt atcgtagaaa atggactcgg tgctatggat
       61 acaccggatg agaatggtta tgtagcagat aactatcgga ttacttactt agaggcccac
      121 atcaaggcca tgcgagatgc catttaccaa gacggggttg acttgcttgg ttatacgact
      181 tggggctgta tcgatctggt ttcagctggc acaggggaaa tgaataagcg ctatggcttt
      241 atctatgtag atcgagataa tgtaggaaac ggagttctca aacgtagcaa gaagaagtcc
      301 ttctattggt acaaggatgt cattgatagc aatggtgcaa gcatcgggta gagcacattt
      361 gtttactatt tttataaaat cttctccctg ctttataaga tgtaaaaaag agttcaattc
      421 gaactctttt tttgctataa tgaggggaga aaaatcagac aggagatcga catgtcagaa
      481 ccattatttt tacaatcagt tatgcaagaa aaaatctggg gtggagccaa gctacgtgat
      541 gagtttggct acgacatccc aagtgaaaaa atcggagaat attgggccat ctcagcccat
      601 ccaaatggag tctctaaagt tgccaatggt cgttacgagg gaacagatct tgctactttg
      661 tatgcggaac accgtgaatt atttggcaat cgtccagaac ctgtatttcc acttttgacc
      721 aagatcctcg atgccaacga ctggctcagt gtccaagttc acccagacga tgcttatgga
      781 ctcgagcatg aaggcgaact cggaaaaaca gaatgctggt acattatcgc agcggatgaa
      841 ggttcagaga ttatctacgg tcacaatgcc aagtcaaaag aagaactccg ccagcaaatc
      901 gaggataaga actgggatgc gctgttgaca aaagtgccag ttaaagcagg agatttcttc
      961 tatgtaccaa gcggtaccat gcacgctatc ggggcgggta tcttgattct tgaaacccag
     1021 cagtctagcg ataccactta ccgtgtctat gactttgacc gaaaggacga taagggcaac
     1081 ttgcgtgaac ttcaccttga aaaatctatc gatgtcttga acattggtga acccgcaaat
     1141 agccgtccag tgacaatcaa agcagatgat ctacgttcca ctctccttgt atccaatgat
     1201 ttcttcgcag tttacaaatg ggaaattact ggaaaagtta actttgaaaa gacagctgac
     1261 tacagcttgt tgagtgtctt ggctggtcaa ggtcaactaa ctgttgacgg gaaaaactat
     1321 ccaatccaaa aagggagaca ctttatccta ccaagtgatg ttgaatcttg gactttagaa
     1381 gggcaagatt tggaattgat tgttagtcat ccataaaaag aaagggcctg agttcactac
     1441 tcaagtcctt tttgattaca taaattgggc gatgaagacc acgatgatga ttggaatgac
     1501 gaaacgaaga aacgaaggag gaagagccag acttggaaaa gtacttgttt ccaggctctt
     1561 tcatcgagat ggagttcctc cataacaaga gcctttttaa agatatagcc tgtaaaaagt
     1621 gaaaggcaga gagctccaaa tggcatgaga agattggaaa ccaagaaatc catggcatca
     1681 aagaaagtct taccaaagat gtgaacatcc gccataactc cataggatag ggctgaagga
     1741 atgccaaaga caaaggtcaa aattcctaaa ataacactcc atttggcacg tttgctgtta
     1801 tcctggttgg tgatattgcc cacattgatc tccagcatca cgacagaaaa agtgactggc
     1861 gcaaaaagga agagcaagag gaaaaggacg tagaaaatgg ttccaaaagg catcttgtca
     1921 aagagttgag gcaagacgat aaagagcaag ctcggtcccc cttcagactg gatattgaag
     1981 ggggaccgag cttggaaaat ggctagacct gccatgatgg atatcgagat attcatggct
     2041 acgatggaga ttcctgactg gactaggttg gttttcttgt ccaagtaaga agcataggtc
     2101 aacatgactg taacccctag tgagagggca aagaaagatt gtcccagagc atagaggaga
     2161 ccagcgctag tcagttttga aaagtctggt ttgaggaagt aaagaacccc ttccatggca
     2221 tttggcaaac tgagagagcg accgatgata acaacaaaga tgataaagag caggggcatc
     2281 atgactttcg aagctctttc aatccctttt tgaaccccac gtgatacaat aaagatattt
     2341 aataagataa aggctgcttg agctcctagg gcaatggctg gatttgaaat gattgaagta
     2401 aataactgag cataatcacc cgttccacca agttggaaca atttcccaaa ctcaatacct
     2461 agatagacta gaatccatcc tccgataaca ctgtaaaaag ataagaggat aaagagggca
     2521 aaggcgccaa tccaaccgat aaagttgtac ttgttattct tgcccagttt tccaaaggtt
     2581 ttgatagcgg aaacgccagc actacggcca agggcaaact cagccagcag gagagggaaa
     2641 ccgattaaaa tagtggaaat gagaaagatt agtaaaaagc ctccatcgcc attagcagca
     2701 gtcatgtagg gaaacttcca aacggaacca agcccgatgg ccagccagca gatgctagaa
     2761 taaaaccaag tttcgacccc cattgtgatt tttctgacat agttaaactc tgatctcctt
     2821 tttcaaaata agaaaaagct acttgagttg tcaaatagcc ttctgtttga ttgatagact
     2881 tgactatcct atcatgtttt ctaaggtctg tcaagaaaat cattttcaag ttttcacacc
     2941 tttctcaaaa aagttaaaaa attttctcaa aaacgcttga ctctgaccta aggggagggg
     3001 ttatactatc attgtaagga ggaaatcatg taccatataa aagaagctgc gcagctttca
     3061 ggtgtctctg tcaagaccct gcatcactat gacaagatag gactcttggt ccccttaaag
     3121 tcggaaaacg gctatcgaac ctacagtcaa gaggatttgg aacgccttca ggtcattctt
     3181 tactacaaat atctaggctt ttctttagag aaaatagcag agctgttaaa ggaagaaagg
     3241 acagatttat tgccccattt gactaggcag ttggactatc taactcgcga aaggcaacat
     3301 ctggatacct tgatttccac cttgcaaaaa actattcaag aacaaaaagg agaaagaaaa
     3361 atgaccattg aggaaaaatt cacgggattt agctatcaag acaatcaaaa ataccaccaa
     3421 gaagcggtag agaaatatgg tcaagaagtc atgggacaag cgctcgaacg ccaaaaaggt
     3481 cacgaagacg aggctacggc cgcctttaac caagtctttc aaactttggc acaaaatctt
     3541 caagttggtt tacctgcaac agcaaccgaa aaccaagagc aagcagccaa gctcttgcaa
     3601 gccattcgca cttatggatt tgactgctct attgaggtat tcggtcatat cggtaaaggt
     3661 tacgtctata acccagagtt taaggaaaac attgacaagt ttggttctgg aacagcccag
     3721 tacacgtcag atgccattgc agcttacgtt cagacaaatg cagaaaaaat aggctaggaa
     3781 tttcctagcc tattttttac ttcaaatcat aaagccagtc gtcaccgttt ttgtagtaaa
     3841 agaattcact gagatcttct tctagaaaca cacgaagcat atcagacata tcatcggttg
     3901 caagttttag atgagaaaga ttttcaaagt cctcccacca aactttccct tcgtctgaag
     3961 actggagttc accagtaaag tgttctgtct tgtaaaaaag gacgacataa cgataatcct
     4021 tgtcgtcata ccagtttttg ataccacaga gttggggttt ggaaatgatc agaccagttt
     4081 cttctttcac ttcacgaatg acagcatcga caaaggattc gccacgttca acatgaccac
     4141 caggaaaagt aatgccaggc cagtcgggac taactcggtc ttggaccagg accttatctc
     4201 cgtttttaat catacacatg ttaacaaatt cgactgcctc tcttctgttc attcttcaca
     4261 acctttaatc tttaatcata atgcagactt cccgccaccc agccggtaca gagggcagaa
     4321 gtgatgttaa agccacccgt gtgggcattg atatccataa cttcgcctgc aaagtggagg
     4381 ccaggtacca gcttactttc aagggtttta ggattgattt ccttgagact gactccaccc
     4441 ttggtaacaa aggactttgc aagggacatt tttccagtta caggaatttt aagttcttta
     4501 atggactgga caagctgttc tcgttccttt tcagtcagct gtttgacttt ttcaggatat
     4561 ccttgtacaa aaaattcggc caagcgttct ggtaacaagg tttttaaagc gtttttcaag
     4621 gatttttccc gattttcttc tagaaatgta accaagtcct tctcagaaag ttgaggcaaa
     4681 acatcgagtg agagaacctc cccacctttg acaaagctag acatgcgtag ggcagcagga
     4741 cctgacaaac caaagtgggt aaagagtaaa tcatgagtga tgacatgctt accataactt
     4801 agggtcacat cgtccaaaga aatcccttgt aaggctttat gtggaaaatc tgttaataaa
     4861 ggactttcag cagcctcaag atcggtgatg gtatgcttaa aatggcgagc aatctcgtga
     4921 ccaaaaccag tcgaaccagt cgaaggataa gacttaccac ctgttgtgac aatgagtttc
     4981 tcacaagtga aggtttgatc cgctgactta aggacaaact ggttatctac ttttttaaca
     5041 gaaacgattt ctatttgagt agcaacttga ccacctagtt cggtgatttt cttttccaaa
     5101 gcttcgataa tagtccgaga cttgtcactg gctggaaaga cgcgtccgtg gtcttcgacc
     5161 ttaagtttaa caccattttc tgtaaaaaag ttgatgatgt catgattatc gaactgggag
     5221 aaaacactgt aaagaaagcg tccgtttcca ggaattccag ctagcaggtt gtctaagcta
     5281 ccattgttgg tcacattgca acgtccccca ccagtcccag ctaatttttt tccaagtttc
     5341 cgattttttt cgatgaggag ggttttctgt ccataaaagc tactggaaat cgtagccatc
     5401 ataccagcag gtcccccacc gatgacaata gtatcaaaat gtttcatagc tctattgtac
     5461 cacaaaaaaa caagagatga tggtcacctc ttgtcaagaa tgcaattaat caatttcata
     5521 gcccatcagc aaaccgccct cttctgcata gaaactgcag agaccagagg ttggtagaat
     5581 tttaatatcc gcttgtggga aggtttcacg gattcgctct gagagctgtt gacaacattt
     5641 ttcgttattg cgttgggcca tgacaatacg gccaccagca tatccagctt ttactaactc
     5701 atcataggca gcttgaactg atttctttga tccccttgct ttttgtagca attcgagagt
     5761 cccagtttca ctagcttttc cgaccatacg aatgttgaga aggccaacga ccgtaccgat
     5821 aagcttgctc aaacggccgt tcttcaccaa gttatcgact ttggctagga caaagagcaa
     5881 cttagttttt tcttgatagg cggtgatagc ttcaaccact tcttcaaaag acaagccctg
     5941 gtcaatcaag tcattcaatt tttctacgag taggtcaact tcaccaccag cagataaact
     6001 atcaatcaca tgaatcttag tgtcaggatg gtcttccaga taaatattct ttgctagttg
     6061 agcactattg tgactgccag aaagggtacc tgtgatggtt actaggaaaa tgtttttggc
     6121 accttcaaat gctcgcaaat agtcatctgg gcttggacaa gctgattttg aagcttctgc
     6181 agttgcatac atggtttcca tcatttggtc aatatcgaga ctggcgtcat caacaaagac
     6241 ctgatcagct acttgaatgg ttaaggggac acttacaaag gttgtgttaa tagctggtgt
     6301 tggcagttga cgataatcac aaccagagtc agcaataatc ttccaagtca tagaaattct
     6361 ccatctttgt cagttataca ttgacaaagg ttctgtcttt ttttacaatt atatcatgaa
     6421 aactcttgaa acaaaagcat catccgtctg ttgtgacaag tagaaagaaa atgttatgtc
     6481 tgaacgtaga atctctgaaa agtctcttga aaatctcaga aaatcaaatc aagaatccaa
     6541 tttattaacc agagaagcca ttgaaacagc cctcttgcaa ctcttggaaa aaaaggagct
     6601 gaccaagatt agtatttctg aattggtcaa acgtgcaggt gtttcgcgtg cggcctttta
     6661 tcgcaattat gactccaaag aggaaatttt agagagcgtc tttaaacgaa ctgtccacaa
     6721 tattatggaa cagctgcatc attacgattt aaagacagac ctttatttgg tttgggttca
     6781 ccttttccgg gaggccagaa aggaagctag agtaattcaa ttggccttgg attaccatct
     6841 ggaaaaaatc tttgtccaag ccatgcagga atttctagaa aaataccatg ggaaatcaaa
     6901 aggtgtcagc tcttatcttc attccttctg gagctcagcc atcgtctctg tccttctaaa
     6961 atggatcaag gatggcatga aggtaccagc tgaaaagatt gcagatttag gtttaccatt
     7021 ttttaaaaaa tagagaaaaa ggagaaaaga gatgactgaa aaaagactgg cctgggatga
     7081 gtattttgca gcccaagccc tactaattgc gaatcgttcc acatgtaaac gtgctaaagt
     7141 gggcgcgatt ctggtaaaag ataataaggt tatttccact ggttacaatg gttcggtgtc
     7201 agggactgag cattgtattg atcacgaatg tttggtcatt gaaggccact gtgttcgcac
     7261 ccttcacgct gaggtcaatg ctatccttca aggtgctgag cgtggtgttc ccaaaggctt
     7321 tacagcctat gtaacccatt ttccttgtct caactgtaca aaacaattgc ttcaggtcgg
     7381 ctgcaagcgc gtggtttata tcaaccagta ccgaatggac gactacgccc aataccttta
     7441 tcaagaaaaa gggacagaat tgacccattt accacttgag acagtacaga cagctcttaa
     7501 agaggctgat ctaatgtaaa aattatcaaa aataaatggt ttagaaagat ttttaaaccg
     7561 ttttttggta taatgagaag aataaattga aagaaggaat tccaaaaatg ggaaaaattg
     7621 aagttattaa tcacccactg attcaacaca aattgtcaat cttgcgtcgt acagatactt
     7681 ctacaaaagc ttttcgtgag ctagtagatg agattgcaat gttgatgggg tatgaagtac
     7741 ttcgtgatct tccactagaa gatgtggaaa tcgaaacacc aattacaaaa acagttcaaa
     7801 aacaattggc aggtaagaaa ttggccatcg tcccaatctt gcgtgcaggt atcgggatgg
     7861 ttgatggtct cttgagcttg gttccagctg ctaaagttgg ccacatcggt atgtaccgtg
     7921 atgaagaaac acttcaacca gttgaatact tggtgaaatt gcctgaggac attgaccaac
     7981 gtcaaatttt tgtagtagac ccaatgttgg caacaggtgg ctcagcaatc ttggctgttg
     8041 attctcttaa aaaacgtggc gcatcaaata tcaaatttgt ctgccttgta tctgctccag
     8101 agggtgtaaa agcccttcaa gaagctcatc cagatgtaga aatctttaca gcagccttgg
     8161 atgaacgttt gaacgaacac ggttatatcg ttccaggtct tggagatgct ggagaccgct
     8221 tgttcggtac aaaataagat cgaaaagaag aatgacttgg aaaagtattt ccagtcacga
     8281 aaggaggttg ggtttttgtt tctgtctaat gaaagcagag caaaaatttg accttttttg
     8341 accaagatat tataatagtc ttatcttcag tcatttgacc aacaaaatta aaactcaaaa
     8401 ggagaaatga atgattcctg tagttattga acaaacaagc cgtggagaac gttcttacga
     8461 tatttactca cgtcttctca aagaccgcat cattatgctg acaggtccgg ttgaagacaa
     8521 tatggctaac tctgttattg cccaattgct tttcttggat gcccaagata gtacaaaaga
     8581 tatttacctt tatgtcaata caccaggtgg ttctgtttca gctggtttgg caatcgtaga
     8641 taccatgaac tttatcaagg cagatgtcca aaccattgtt atgggaatgg ctgcatctat
     8701 gggaacagtc atcgcatcaa gtggagcaaa aggcaaacgt ttcatgcttc caaatgctga
     8761 atacatgatt catcaaccaa tgggcggtac aggtggtggt acccaacaaa ctgatatggc
     8821 tatcgctgca gaacacttgc tcaaaactcg taataccttg gaaaaaatct tggctgaaaa
     8881 ttcaggtcag tcaatggaaa aagtccatgc agatgcagaa cgtgataact ggatgagcgc
     8941 ccaggaaaca cttgaatatg gctttattga tgaaattatg gccaacaatt cattgaacta
     9001 atgatgatag aaggcaaact cgactgggtt tgcttttttt ggtataatag ggagagattt
     9061 cttagaaaga ggatttatca tgtttgaaaa agtcaatcgc tctggcttga ttatctatct
     9121 ttactataat cgtgatgcca aaaaactgca ggattatgga gatattacct atcattccaa
     9181 gaaacatcgt tacttacaac tctatgttcc aactcaagaa gtggagcaat tggtcggacg
     9241 cttgagcaag gaaaaattta ttaaaaaagt tagagtttgt catatccaag agttggaaac
     9301 accctttgtg ggcaatcttt atcgatagga aaacgttatc atcgaaaaag ttcaaggaaa
     9361 acattgacaa ttttctgata attcggtata ttcttaacag actatttaag aaataaggag
     9421 acaaaaaaga tgaagaaaaa atttgcccta tcgtttgtgg cgcttgcaag tgtagcactt
     9481 cttgcagcct gtggagaagt gaagtctgga gcagtcaaca ctgctggtaa ctcagtagag
     9541 gaaaagacaa ttaaaatcgg gtttaacttt gaagaatcag gttctttagc tgcatacgga
     9601 acagctgaac aaaaaggtgc ccaattggct gttgatgaaa tcaatgccgc aggtggtatc
     9661 gatggaaaac aaatcgaagt agtcgataaa gataataagt ctgaaacagc tgaggctgct
     9721 tcagttacaa ctaaccttgt aacccaatct aaagtatcag cagtcgtagg acctgcgaca
     9781 tctggtgcga ctgcagctgc ggtagcgaac gctacaaaag caggtgttcc cttgatctca
     9841 ccaagtgcga ctcaagatgg attgactaaa ggtcaagatt acctctttat tggaactttc
     9901 caagatagct tccaaggaaa aattatctca aactatgttt ctgaaaaatt aaatgctaag
     9961 aaagttgttc tttacactga caatgccagt gactatgcta aagggattgc caaatctttc
    10021 cgcgagtcat acaagggtga aatcgttgca gatgaaactt tcgtagcagg tgacacagac
    10081 ttccaagcag cccttacaaa aatgaaaggg aaagactttg atgctatcgt tgttcctggt
    10141 tactataatg aggctggtaa gattgtaaac caagcgcgtg gcatgggaat tgacaaacca
    10201 atcgttggtg gtgatggatt caacggtgag gagtttgtac aacaagcaac tgctgaaaaa
    10261 gcatcaaaca tctactttat ctcaggcttc tcaactactg tagaagtttc agctaaagct
    10321 aaagccttcc ttgacgctta ccgtgctaag tacaatgaag agccttcaac atttgcagcc
    10381 ttggcttatg attcagttca ccttgtagca aacgcagcaa aaggtgctaa aaattcaggt
    10441 gaaatcaagg atagccttgc taaaacaaaa gattttgaag gtgtaactgg tcaaacaagc
    10501 ttcgatgcag accacaacac agtcaaaact gcttacatga tgaccatgaa caatggtaaa
    10561 gttgaagcag cagaagttgt aaaaccataa tagaaaaatg ttgaaatagg gaatgagcct
    10621 ttgactcact ccctgtttcg atatttaata ctcttcgaaa atctcttcaa act
//
LOCUS       DBEJKC010000061        10662 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.061, whole genome shotgun sequence.
ACCESSION   DBEJKC010000061 DBEJKC010000000
VERSION     DBEJKC010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10662
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.061"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(21..1445)
                     /locus_tag="ACL3G6_001757"
     CDS             complement(21..1445)
                     /locus_tag="ACL3G6_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HGR0546239.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMLKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVTWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(1990..4269)
                     /gene="pulA"
                     /locus_tag="ACL3G6_001758"
     CDS             complement(1990..4269)
                     /gene="pulA"
                     /locus_tag="ACL3G6_001758"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051060 - pullulanase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HGR0546240.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4381..6339)
                     /gene="ligA"
                     /locus_tag="ACL3G6_001759"
     CDS             complement(4381..6339)
                     /gene="ligA"
                     /locus_tag="ACL3G6_001759"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HGR0546241.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSISKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6432..7610)
                     /locus_tag="ACL3G6_001760"
     CDS             complement(6432..7610)
                     /locus_tag="ACL3G6_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0546242.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7690..8553)
                     /locus_tag="ACL3G6_001761"
     CDS             complement(7690..8553)
                     /locus_tag="ACL3G6_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGR0546243.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISSHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8556..10457)
                     /locus_tag="ACL3G6_001762"
     CDS             complement(8556..10457)
                     /locus_tag="ACL3G6_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR0546244.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSALYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         3182 a         2364 c         1904 g         3212 t
ORIGIN      
        1 caatttcctg attttacacg ttatttcaca tcaaaaacaa tggatttgac atttgtcatc
       61 gcttcaatgc tatatttaat tccttgcact ccagctccag aacctttgac accaaggaat
      121 gggaaattat ctggaccacg ctgggtttta ttattaatgt ggactgtacc tacttcaagt
      181 ttttcagcaa tttcaaaggc ttttttgaaa tcatttgtaa agactgatga ttgaaggccg
      241 aattcagatt cgttggcaaa ggcaatagct tcctctacac tagccacacg aatgattggt
      301 aaaacaggac caaatggctc ttcccatgtc actttcatat cttttgtaac ttggtcaaaa
      361 agcactggcc agaggagatt gccctcacgt ttgattggtg taagagcctg agcctctttt
      421 tcttgtgcat cctcaatcaa gccccaaatg aagtcggctg aagcattgtc aataacaggt
      481 gtaatatcag cattgtcaaa tggatcacca actgttaatt tagaaacttc ttcctgaagc
      541 aaagtagcta atttatctgc tacactttcg agaacaatga cacgtttaat ggccgtgcaa
      601 cgttgtcctg agtagctaaa ggctcccgca acaatttgct tggcagcatg ttccaaatct
      661 gcatcttcta gtacaagagc tgcatctttc ccaccaagtt ccaacatgat aggacgcata
      721 ccagctaaac gaccaatacg ttctccaata ggagttgaac ctgtaaagtt gatgaagttg
      781 acttctttgt gctcaatgat ataatcccca atttctgaac cacgacctgt aatggtgttg
      841 aaaacacctg ccggaatccc tgcttcttca aatgctttag ccaacaagag tccagaaatg
      901 gaaccttgtg ttggtggctt caacatgacc acattccctg caatcaaggc aggtgcaatt
      961 ttagaagcag ataaattaac tggataatta aagggagcaa tcgctagcac gataccaact
     1021 ggttcacgac ggacaacagc cagtttgttt ttacttgctg cctcaaaacc accaccttcc
     1081 attgcttgtc cagtgatacg gagaccttcc tcagcagcat aacgaatcaa gtctgctgta
     1141 cgcactactt ctccaattgc tgctttaatc ccttttgcta cttctttggc aaggatagta
     1201 ccaatttttt ccttatcgcg ttctaaaata gctgctgttt tatgcaaata agccgcacgt
     1261 tcaattgctg ataaagctcg ccatgctggc agggctgcac gcgcagcttg catagcctca
     1321 tcagcttcag tctgagtcat ggctggaact gtacccaatt cttcttgatt gattggtgaa
     1381 taaatcgtaa tttcttgttc agatgatttc cattttccat ttactaaatt ctgatatctt
     1441 gtcaaattct tgtcctcctg aaaatgatta agatatattt taccaaattt tcagaaaatc
     1501 acaacccttt ttgcaaaatt tttgagatta ttttcacaat cttgattttt caaagtatac
     1561 tcaataaaaa ttaaaaaaat ccactacgtc aaggcgaggc taatgtggtt tgaagaaatt
     1621 ttcgaagagc atgaatgagt atcatctata gtaaaataaa aaaactgaac aatttggttg
     1681 gggacagcca aaccaatttc tcacaatgtt tcagaaacaa gggtgtgcta ttccaatttc
     1741 agcctactat aactgtcata gattgctgaa acaaagtcta ggtaaaagtc ttcataataa
     1801 aaagacctcc tatcaagtgt tcaaaaactt tgataggagg tcttgttttg tgaaaatatt
     1861 tatcaaattt tctatacaag tgagctgtta gccaggttct ttctattctt tcaatttcaa
     1921 tgaatggatt ttttactaat actcataact gggaatttgt ctgtgtaaaa atagcgagat
     1981 agatggtatt tataaaacac tcaagacagc tagactaata tcatttaaaa cattatcttc
     2041 ttttgagcga ctgttggtta ccaacatagc taaatttcct gcattttcaa attgataggg
     2101 ttctgattta gcattcacaa ctaccaagag gtgttctttg ccgtgaactt catagataag
     2161 gcagccgcta tgttcaatcg cagaatgcac aaagacatga tggtaaattt catcatagct
     2221 agagtaagaa aaggcaccag tttttgtctt caatcggatg acttgacgga taaactcaat
     2281 actgtcttga cgctcattaa tcaagttcca gttcacttgg ttcacactgt caggagcatt
     2341 atagctattc atcgcacgct ctctatcatc atgggtcaac tcaccatttt caccagtcgc
     2401 aaccagtttg gtacgaccaa attcttgacc gatttccata aaggccatcc cctgcatgag
     2461 cagattcatg gctgtggcag tttcgacctt gcgcatgatt tgctctgaac tttggtctgg
     2521 atgaagggtt gccaataaat cgtgaagatt gtaattgtca tgggcttcta catagttaag
     2581 cacctgattt ggatgtgtat agcttcctaa ttcacgactt cctaggattg ctttagctag
     2641 aattggctct gtcgcagcac cactgacaaa acctgacttg atagcaccat aaacttctcc
     2701 ccctttgaca gcatcgcgct gattgtcatt aaagaaacca atatttggca tctggtaggc
     2761 attgtccttc ttggccttat cataaggggc aagacctgtt cccatatccc atccttctcc
     2821 atagaggata atgttggagt cgatttcatc caagctttga cgaatcatct gcatggtctt
     2881 gacatcatga atccccatca agtcaaaacg gaagccgtca atattatatt cctgcaccca
     2941 gtatagaaga gaatcaatca tatacttgcg aaacatttcg tgttcactgg ctgtttcatt
     3001 tccaacaccc gttccattct ggaaggtacc atctggattc atacgataat agtaatcagg
     3061 gactgttgtt tggaatggtg catcaacaac tgagaaggta tggttataga ctacatccat
     3121 aatgactcca atacccgcat cgtgataagc ttgaaccatc accttcaaat cacgaatgac
     3181 ctgagctgga tcatctggat tagttgaaaa actagtttct ggcgcgttat agttttgtgg
     3241 atcataaccc cagttgtagg ttacatttcc atcctcatcg tattctttat gacggtctgc
     3301 aattggttgc aattgaacat aattgtagcc cagcttcttg atgtaatcaa aagcagttga
     3361 ctggccgtat tggttaactg ttccagcctg agcagcaccc aagaaagttc ctcgaagatg
     3421 ttcatctaca cccgatgtag gtgatttagt caaatcacga atgtgcattt cacagataac
     3481 tgccttacat ggattttcca agcgccaagt agcctccgaa ccgtgcttaa cctcgaagtt
     3541 ttcaacttgc ttttctacat ggctcagaat agctgaacgt ttgccatcag ggctggtcgc
     3601 gattgtataa ggatcacgtg tcagtgtttg gtgatgaggg aattggactt gatactgata
     3661 agtcttacct accaaatctt cttcaacatc caaactccag acaccgattg tattgtcctt
     3721 atgattataa gagtagctat tgcctctttt catctcaaaa gtcttccaaa cgggtgcatc
     3781 attagcagct gattcataaa cgacaacttg cacttctgtc gctgtaggtg accagagaga
     3841 aaaatgagcc tgattgtcct ctacacggca acccaattct ccttggtaac cccaatgatg
     3901 atcaaaacta gcactgttaa tggccttatc aaaggcaaaa ggattttgat ttttatagaa
     3961 aggactggca atagcaggat tttcagagta ataaatccta tcatcgcctt ccaaaatcca
     4021 gacctctgtt aataggggat agtgattaaa acggatagaa tattctttac tagtttgacc
     4081 tgtatgaacc acaaaattca agctttctat aacatgtgaa cttgggtgtt caaagctaaa
     4141 taaagctcca aaataatctt ctttgtaggt tagcaaatca attcgttgat cctgactttt
     4201 tacaaaggag caagtgtcat attctccatt cttacgatgg taatgaatgc gcatagggta
     4261 gttatacatt ttttattttt cctttttact ttgtttctat ttcactaata aatttttgtc
     4321 aatctcgtct caattaacag acatagtcat attctctaaa ctctgttttt aaacgatcca
     4381 ttacaaactt tctagccatg cctcatctct gacctggata ccaagttctt gtgctttttg
     4441 cagtttactt ccagcgtctg cacctaccac gacgaggtcg gtctttttag aaatactacc
     4501 tgtcactttg gcacccagac tttcgagttt acttttagct tctgagcgct tgagtcgttc
     4561 caattttcct gtcaatacca cggtcaaacc tgacaaggcc gcatccgcta ctaccgtctg
     4621 tcctttatag tccagattga ccccagtttc tttcaattct ctgagcagaa tttcagagcc
     4681 ttctgtcgca aaataagtct gaagactttt ggcaatcacg ccacctagac tttcaatact
     4741 agccacttcc tctgaatctg cctgagacag attttcaatt gaatggaaat attgaagtaa
     4801 aagctgacta accttgcttc cgacatgacg aattcccaaa ccaaataaga gcttctcggc
     4861 agagttttcc tttgatgctt ggatagcctg atacagttta gcagcggact tttccttaac
     4921 cccctctaaa aggaggaaat cctcttcttg caaacgataa atatccgcca catccttgac
     4981 taaattagca gcaaaaagct tctcaacaat agatggacca aggcctgtaa tattcatagc
     5041 atcacgagaa gcaaagtgaa tcaagccttc catgatttga gcagggcaac gcggattgat
     5101 acaacgtagg gccacttcat cttcaaagtg caacaagtca gagttacaac ttggacagtt
     5161 tgtagggata tctagttttt cttcagaaac ccgtttggac tctaccacac gtaaaacggc
     5221 agggatgatg tcaccagcct tatatacaat gaccgtatcg tcttttcgga tatctttttc
     5281 agcaatataa tctacattgt gcagggtcgc acggctaaca gtcgtaccgg caagttgtac
     5341 tggtgttaga ttagcagttg gagttacaac accggtacgg ccaactgtcc agtcaactga
     5401 taagagttga gcttcttttt cttcggcagg gaacttgtag gctactgccc actttggagc
     5461 cttaacggta aaaccaagtt cttcttgact tgctaggtcg ttgaccttga ttaccactcc
     5521 atcaatatcg taaggcagat tttcccgttc ctgtcctact tcttggataa aattccagat
     5581 ttcatctatg ttttcagcca agattcgctt aggattgacc acaaaaccta gttgttctag
     5641 gtacttcaaa cccttttctt ggctatcacg agttgaaggg ctggcttctt gatagagaaa
     5701 cgttgcaaga ttacgcttgg caactactgc tgtatccaac tgacgcagag ttcctgctgc
     5761 cgcattacga ggattagcaa attcaggctc tccattttct tggcgcactt ggttaacttg
     5821 gtcaaaggaa gcgcgtggca tgtaacattc cccacgaact gtgatatcta gttcttctgg
     5881 caaagtcaaa gggatgtcct taacacgctt gaggttttct gtgatatttt caccaattga
     5941 accatctcca cgtgttaccc cagcaaccaa aatccccttt tcataagtca gcgagataga
     6001 taagccatcg attttcagct cacaaatata ggtcggatga gccacttcct tacgaacacg
     6061 cgcatcaaaa gcatctagct cctcacgtga aaaagcatcc tgcaaactat aaagaggata
     6121 ctgatgactg tatttttcaa aaccatctaa aaccttgcca ccaacacgat gagtcggact
     6181 gtctgctagc acttgctctg gataagcagt ttctaactcg accaactcac ggtaaaggcg
     6241 gtcatactca ctgtctgaaa ccgagggatt atcgctggta tagtactcag tcgcatagcg
     6301 attgagcaaa gcgactaact cattcattct tttattcata agaccatttt accataaaac
     6361 aagccctcct cacaaacgag aagggcggaa aaaacactta gtttgaaatt atttttgaaa
     6421 ctcaagcaac cttatatcaa tttttcaaaa tgagttcgaa cataaataaa cgatatacaa
     6481 gacaagatga taacaccact tccaattatc aggaaagaag agagatgtac acttggcaag
     6541 actgtcataa atccttttgc aataggcata aatagaatag ctaaggtaaa aattgtactc
     6601 agtactcttc caagaaattc gctctcaacc ttggtttgta cttgagtaaa aaagtgaata
     6661 ttaaaaatcg tcataaacaa ttcacaaact aaatttccag aaaaggaaag aaaagttgga
     6721 agtggtaatc ccatcataaa aactccgaca cctgtcaaag ccagtaaaat caaaagatta
     6781 taaatattag ctttaatttt actagctaga agagccccaa tgatggaacc aatagccccc
     6841 atagttaaaa tacttgcata ggctccttct gacccgtaaa gctgattcga aaagggaagt
     6901 agaaattcaa aagctgcaaa aaagaaatta acgctggaag ctaccagcaa aaggaagaaa
     6961 atttcttgct gatgccagat atagtgtaac ccatccttga tatctacaaa aatatctctc
     7021 ccagtaaaag cctttttctc ttgaactttt gcttcctctt ttggaaggaa agccactaga
     7081 acaaaagcaa tgaaaaaagt cagcgagtct agcagtagcg tcatatggag acttgcaaac
     7141 tgtaaaacaa ggaaggaaag aacaggagag ctaacaccta caacctgcaa aaccagctct
     7201 aggcgagaat tatagatcac aatctcatct ttctccacca cttcagttat gatagcttta
     7261 ttggctgtgc gagaaaaggc aaaagcaata gcctgcacaa tgttagcaac aatcaaagcg
     7321 ccaatcatcc agctatcatt ccttatgaaa gaaatagcca gacaaagaat cccacaaaca
     7381 agatctgccg tcattaaaat cttacgacga gaaaaacggt ctgaaataac tccgccaaag
     7441 ggattgacga gaatagatgt gacgagctca gaaatctgat acattcctaa aactgtctgt
     7501 cctatagtcc ccatagaagc caaccagaca ctatttccat aatcatagag catatttccc
     7561 attttattga tagccccacg gctaatcaac tgcactgcat agcgattcat attaaagctc
     7621 ctctcaaatt ttgaaactat tgtatcaaaa ccgaaaggag ctttttattt tttcccttat
     7681 ttgggaaaat taacttttga caaatttttc gtagtgttcc tgataatagg ctacttgctc
     7741 tggaagacct aacacatcaa aaatatgtat ggcctcttgc atctgcttac agccttcttt
     7801 acactgtcct ttttgatata aggcaaaacc ttttaaataa tggaaaacat tacgctcata
     7861 aagcttaata cctttgtcaa taatcttctc tgtataagcc tcaaaatagt tggcattata
     7921 aaaagaagaa tgctctaaac aatgctggta acaattgagg gccaaaatca acactaatct
     7981 cttatggcta ctaatctctt ggtaaaattc ctccctctcc ataacttctc taccaatccg
     8041 agtgacataa tccacatcgt agaaactata gaggttaccg aaaagaatca actcatacat
     8101 ggtccattct tctgttttga agagataatc tgctacctta tccaaatcat cctgcttcat
     8161 atcataactc gcatctcttt gacaaatcag accctgtagc aaaatccagt tcagctcaaa
     8221 ataaagggga gtcgtcgaac tcttagactt ttcaagttgt tctctttgaa gcttttgaaa
     8281 acctgcaata tcgtttgaat agtaaagtgg gataatctgt gccatcatag acacatgttc
     8341 atgattatga aaattccttg ccttatccat gaaattttcg attgttacat gaatgttatc
     8401 caaaatctca aagaaacggg agactgccag gtcagactcc ccaagctcaa agcgagataa
     8461 ctgagaggta gagcaggatt cgcctgctgc ttccttcaaa gaataatttc cacttgttcg
     8521 aaattcacga aatacttttc caagatgttc catctttaca cctgctctga taattcttcc
     8581 cactcaagca tagcttcttc ctgacgatgg ctgattttgt ccagctcagc ctgtaattcc
     8641 atgagtttgt cggcatcgtt tgtttccaac atttgttcag aaatggcttg gctttgactt
     8701 tctagctctt caatttcagc ttctagactt tcgatttgtc gcatgagttt gcgaacttct
     8761 ttttgacttt ctttctgggc ctgatagtca ttgactggac ttgcttcctt tgcttgattg
     8821 ctagttgaag cttcctcagt ctgactcatt tctgctgttg ctttcttctc aacatagtag
     8881 tcgtaatctc caaggtagag agctgaacca ttctcagaca attccaaaac atgagttgcc
     8941 acacgattga taaagtaacg atcatgactg acaaaaagca aggtaccatc aaagtcaatc
     9001 aaggcatttt ctagcacttc cttactatca atatccaagt gattggtcgg ctcatccaga
     9061 atcaaaaagt tattgttttc catagacaat ttagctaaaa gcaaacgagc tttttcgcca
     9121 ccagatagca tgccgactga ttttttaaca tcatctcctg agaaaaggaa ggctccaaga
     9181 cggttgcgga tttcaacttc tggtgtcaat ttgaaatcat tccagagttc atccagcacc
     9241 gtattacttg gtgtcagctt gctttgggtt tggtcatagt aaccaacctc aacattagcg
     9301 ccaaagcgct tttctccctt gataaacgga atttgatcca cgattgattt gataaaggtt
     9361 gattttccga taccattggg accaacgata gcaacagcat tcatcttacg aaggtctagg
     9421 ttaatcggtt gtgacaggac ttccccatca tagccaacag ccgcattttc aacagtcaaa
     9481 acaacattgc ccgacgtttt ttcagactgg aaggtcatgt tggctgcttt cttgccagct
     9541 tccggcttgt ccaaacgctc cattttttct agttgtttac ggcgagattg agcacgttta
     9601 gtcgttgaag cacgaactag attgcgattg acaaagtctt ccagagcagc gatttccttc
     9661 tgttgctttt catagttttt tgcctcagta gctagctttt gctccttcaa ctcgacaaaa
     9721 cgagagtaat tccccacata gcgatccaag gaatgcttgg tcaaatctag cgtaattgtc
     9781 gcaaccttgt ccaagaaata acggtcgtgg ctgacgataa tgagggcacc gctatagttt
     9841 accaagtaat tctctagcca ggagatggtt tcaatatcca agtggttagt tggctcgtcc
     9901 aagaccaaga gattgggctt ttcaaggagc attttagcta gagccaaacg agtattttga
     9961 ccacctgaaa gttcagctat tttcatctgc cacatagact cgtcaaactt gaatccattc
    10021 aaaatcgctc gaatatcagc ttcataggta aagccacctg cttggcgaaa attctcagat
    10081 aagcggtcat aatctgacat cagtttatcc aaatcctcac cagacttttc acccatctcc
    10141 agctccatct gacgcagttg tctctccgtc cgacgcaaat cattaaagac atgaagcatt
    10201 tcatcgtaga tggtattttc agactcaaaa cggctatctt gggctaggta agacagagaa
    10261 atatcttttt tcttattgat ttctccgcta gttggctcct cttctccaac taaaatcttc
    10321 aaaagagtag acttacctgc accatttttc ccaacaagag caatccgatc tcgttcatca
    10381 acctgcaggt tgatattatc gaaaagaacc tctcctgcaa aagaacgttc aattttatta
    10441 gcttgtaaaa taatcataag agtagtatag catgtttccc taaggcattc aagataatcg
    10501 taagtctttt agtacaactt ttataacata aaataaacta aattatgtat attttatatt
    10561 agattccttc actatcttgt tggattttct aaccagctaa tcttgtttca aatagttatc
    10621 gcacaagcct attatttaat tcttttcatt atttacgtac gc
//
LOCUS       DBEJKC010000062        10593 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.062, whole genome shotgun sequence.
ACCESSION   DBEJKC010000062 DBEJKC010000000
VERSION     DBEJKC010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10593
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.062"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(2..238)
                     /gene="rpsT"
                     /locus_tag="ACL3G6_001763"
     CDS             complement(2..238)
                     /gene="rpsT"
                     /locus_tag="ACL3G6_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HGR0546245.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(306..1226)
                     /gene="coaA"
                     /locus_tag="ACL3G6_001764"
     CDS             complement(306..1226)
                     /gene="coaA"
                     /locus_tag="ACL3G6_001764"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HGR0546246.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDSDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            1416..1819
                     /locus_tag="ACL3G6_001765"
                     /pseudo
     CDS             1416..1819
                     /locus_tag="ACL3G6_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2026..2616
                     /locus_tag="ACL3G6_001766"
     CDS             2026..2616
                     /locus_tag="ACL3G6_001766"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0546247.1"
                     /translation="MSKMYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDF
                     GSQLLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEK
                     NNAKATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQ
                     KKQGAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            2613..3890
                     /locus_tag="ACL3G6_001767"
     CDS             2613..3890
                     /locus_tag="ACL3G6_001767"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HGR0546248.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            3908..4570
                     /gene="deoC"
                     /locus_tag="ACL3G6_001768"
     CDS             3908..4570
                     /gene="deoC"
                     /locus_tag="ACL3G6_001768"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HGR0546249.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            4557..4946
                     /locus_tag="ACL3G6_001769"
     CDS             4557..4946
                     /locus_tag="ACL3G6_001769"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGR0546250.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAVFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            5036..6088
                     /locus_tag="ACL3G6_001770"
     CDS             5036..6088
                     /locus_tag="ACL3G6_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HGR0546251.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            6232..7767
                     /locus_tag="ACL3G6_001771"
     CDS             6232..7767
                     /locus_tag="ACL3G6_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0546252.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINMHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVAGISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            7760..8818
                     /locus_tag="ACL3G6_001772"
     CDS             7760..8818
                     /locus_tag="ACL3G6_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0546253.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLTELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            8821..9777
                     /locus_tag="ACL3G6_001773"
     CDS             8821..9777
                     /locus_tag="ACL3G6_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0546254.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            9862..10593
                     /locus_tag="ACL3G6_001774"
                     /pseudo
     CDS             9862..10593
                     /locus_tag="ACL3G6_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         3092 a         1861 c         2429 g         3211 t
ORIGIN      
        1 cttatttagc aagtttagct gaaagacgag ctttatcgcg gcttgctttg tttttgtgaa
       61 tcaaaccttt agtttctgct ttatcgatag ctgagctagc agcacggaaa agttcttcag
      121 atgggtttgc ttcgaaagct tttatagcag tacgcatagc tgatttttga gctgagttct
      181 tttcgttttg tttaacgttc aattcagcgc gtttgatagc tgatttaatg tttgccaatg
      241 ttcttacctc catatttact aactatacca ttatatatga aaacttacgt tttgacaagg
      301 gaaaattatt tttttaagta aatttcatcg atttcatggt tcttgctttt atgaagaatc
      361 acttctgcac gatttctggt tggttcaata taattttgta gatttgtgag attgatactg
      421 gtccagacct gatgggcaaa ggcttccact tccccaatcg gcatctgagt aaaacgataa
      481 tagtagctat cagagtcgtt ttgggctaga ctcagcattt tcaagaaacg gtccagatac
      541 caactttcaa tatcatccac tccagcatct acatagatgg aaaagtcaaa gaagtcagtg
      601 atatagagac gatcgttttg tggattttga aagacattga ttccctcaac aattacaaaa
      661 tcagcagctt tgacactttg tttctcttcg ggtacgatgt cgtaaacttc atgagaatag
      721 acaggaatat ctacatcttg tccatttttg atgcggtcca agaagttgag aagagcttcc
      781 atatcatagc tttcaggaaa tcctttacga tttaaaatcc cctgctcaat caaggtttga
      841 ttgggataga gaaaaccatc agttgtaacc aactcaaccg tagcatctgt aaacgtacgg
      901 gacagtagga tttgaagtag gcgactggtt gtggattttc caacggcaac actcccagaa
      961 accccaataa taaaaggttg agatttactt tcacgttgga ggaaaattcc ttttgaaaag
     1021 gctaaatctt ccttagttcg cttgtaaatc tgaatcagat gagccaaggg gagatagata
     1081 tctgtaacgt cttggagact gatttggtca ttaaaactct tgatagattc caattcttct
     1141 tctgtcaaag gaggtgttgt ctttcgatgt aaagattgcc aagtctggcg gctgattttt
     1201 tcaaaatgta aaaattcgtt ggtcatttgt tttcccctag atattttgtc tatcatacca
     1261 taaaaagcta aaaaaataaa gcggtttctt gaatgtggta agtcaatggt atatagtata
     1321 agtgatcaat ttattgatga aataggagat agattctact gatttataag cttataaagg
     1381 gggcttttta gttcacaact tataggaggt gtactatgaa aatcttaaaa cgttacatat
     1441 tggaactctg ttttatttta agttttgctt taccttttat aaaaggagcc aatgcagata
     1501 atggtagatg ctttgtggaa acctattacg gttttacttt tttgatggaa catgctattg
     1561 taacagctgt ctttatctgt tcgttcttaa ttgctttctt actaaaaaac gatgggcgaa
     1621 atggattgct gcgggtagtt attgcttttt agtcctacgg attgcgacag agggttattt
     1681 cttccacatg tcactagaag atttgatacg actttggaca agtttggaaa tcctgacaca
     1741 aacgtatcag ttgggctttt atctaaacat tttgttagga attttgttga taataaagta
     1801 ttttaaggtt aagcaataga aataataatc tgcctgatta tagatgataa actttttgtt
     1861 tttatctgga ctgtgatatt tatagttcta aatggtttat tatttataag tgttgaaaga
     1921 gattgaagaa aatggcttcg tgacttgctt tcttcggtct ttttcgtttt attatcaatt
     1981 tgtaaacgat ttacaatttg agtcaaatta tggtaaaata gtgtcatgag taaaatgtac
     2041 tatgcagaaa atcctgacgc tgctcacgac attcatgagt tgagagtgga cttgttggga
     2101 gaaaaaatga cttttttgac agatgcgggt gtttttagca agaaaatggt tgactttgga
     2161 agtcaactct tgctcaagtg tctggatgtc aaccaaggag agacagtcct agatgtaggc
     2221 tgtggctatg gtccattagg tttgtccttg gtcaaggttt acggagttca ggcgaccatg
     2281 gttgatatta acactcgtgc cctggattta gctcagagaa atgctgaaaa aaataatgca
     2341 aaagcgacga tatttcaatc taatatttat gcaagagttc aagggcgatt tgaccatgtc
     2401 atttccaatc ctcctatccg tgcgggcaag caagtcgttc atgaaatcat cgagaaaagt
     2461 aaagatttct tggaaattgg tggagatttg accatcgtca tccagaaaaa acaaggagct
     2521 ccaagtgcca agtctaagat ggaagatgtg tttggcaatt gtgaaatcct taaaaaagac
     2581 aagggatact atatccttag aagtgtgaaa gaatgagagc agttgattta atccaaaaaa
     2641 aacgagacgg tcaagaactg acttcaagtg aaattgaatg gctgatagaa ggctatgtat
     2701 caggaactgt tcctgattat cagatgtctg cctttgctat ggctgtttat tttaaaggaa
     2761 tgacgactcg agaaatctct gatttaacga tgaatatggt taagactggg caagagtttg
     2821 acctgtcagc cattgatggt gtgaaagttg acaagcattc tactggtggt gtcggcgata
     2881 aggtaacctt gattttagct cctcttgttg ctagcttcgg tgtgcctgta gcaaaaatga
     2941 gtggtcgtgg tcttggccat acaggcggaa caattgataa attggagtcc attaagggct
     3001 atcaagtaga acgtagtcaa gaggatttta ttcgtcaggt tcaggatatt ggagtatctg
     3061 tcattgggca atcagaccag ctggtcaaag cagataagct tctctatgcc cttcgtgatg
     3121 tgaccgcaac tgtcgacacg attcctttga ttgcgagttc ggtgatgagc aagaaaattg
     3181 cggcaggggc ggatgctatt ttgctagacg tgactgtcgg tgagggtgcc ttcatgaaga
     3241 cggttgatga ggcgcgtgag ttggctcaaa ctatggtaga tcttggtaag gttgttggac
     3301 ggaagacagt agcagtgatt acggatatga gccagccttt gggacgagcg attggaaatc
     3361 gtctggaaat ccttgaagca ttggagattt tgcaaggtca aggacgtcag gatattaccc
     3421 actttatttg tgaattggct caaattatgc ttggtttggc aaatgttaac aaaactgttg
     3481 aagaagttcg ccaacatctt gaaaatggtc aagcactggc taagtttgag gaaatggtgc
     3541 aagcccaagg tggagacttg gaagacctct atcgtcctgt aaatgtagct catgtggtgg
     3601 aaatccctgc tcaggaaacg ggtgtcattt cagctcttcc agctatggac tttggtcttt
     3661 atgccatgag gctgggtgct ggtcgtgcag ttaagtctga tgtcttggac tatgaaacag
     3721 gaattgtttt tgaaaagaag attggagact ccgttcaaaa gggtgaaatt gttgcaaaag
     3781 tatacacaaa tgaaaaaatt ccacctcaac tagttacaga tttccaaaaa tgtgttaaaa
     3841 taagtgatga agtgaaaaaa atccgtgaaa ttgtagaaat catctcctaa atggagggaa
     3901 aaccgaaatg aaattaaata aatatataga tcatacgctt ttaaaacaag atgcaaagaa
     3961 aaaacaaatt gatagtttgt tgtctgaggc tagagagtat gactttgcca gtgtttgcgt
     4021 taatccgacc tgggttgaac atgctaaaaa aggacttgaa ggcacagatg ttaaggtttg
     4081 cacagtagta ggtttccctt tgggagcaac aacttcagcc gtgaaagcat ttgagacaaa
     4141 agaagctatc caaaatggtg cagatgagat tgatatggtg atcaatgttg gagctctcaa
     4201 atcaggtaat ttagccttgg ttgagtcaga tattcgcgca gtagtggaag caagtggtga
     4261 taagttagtg aaagtcatta ttgaagcttg ccttctgaca gaccaagaaa aaattgttgt
     4321 ttgccaattg gcccaaaaag ctggggctga ctttgttaaa acatctactg gcttttcaac
     4381 tggtggtgct acgatagcag atgttagatt aatgcgtgaa acagttggat ctgatatggg
     4441 agtcaaggct gctggtggag ctcgttctta tgcagatgct cttgcctttg tcgaagcagg
     4501 tgcgacccgt atcggaacgt cagctggggt agctatttta aaaggagaat tggcagatgg
     4561 cgactactga gttgattgaa ctggcaattg aaaccagcaa acatgcctat gtcccctatt
     4621 ctcactttcc tatcggagca gttttagtag ccaaagacgg aagtgtttac acgggagtga
     4681 atatcgaaaa tgctagctat cctttgacca attgcggtga gagaacagct gtttttaagg
     4741 ctatatctga aggccaaaga gaattttcag aattgattgt ctatggtcaa actgaaaaac
     4801 cgatctcgcc atgtggtgct tgtcgccaag taatggtcga attttttgaa caagatttaa
     4861 aagtgacctt agtcgcaaaa gataaatcga cggtcgagat gacggtcggg gaattacttc
     4921 catactcttt tacagactta aactagtctg agtcgctctc tgagtggcac ggtccttgtg
     4981 gccaaccaat ccatacttgc aacatcgttg cacatcttat ttaggaggtt cagtaatgaa
     5041 caagaaacaa tggctaggcc ttggtctagt tgcagtggca gcagttggac ttgctgcatg
     5101 tggtaaccgc tcttctcgta acgcagcttc atcttctgat gtgaagacaa aagcagcaat
     5161 cgtcactgat actggtggtg ttgatgacaa atcattcaac caatcagctt gggaaggttt
     5221 gcaggcttgg ggtaaagaac acaatctttc aaaagataac ggtttcactt acttccaatc
     5281 aacaagtgaa gctgactacg ctaacaactt gcaacaagcg gctggaagtt acaacctaat
     5341 ctttggtgtt ggttttgccc ttcataatgc agttgaagaa gcagctaaag aacacactga
     5401 cttgaactat gtcttgattg atgatgtgat taaagaccaa aagaatgttg cgagcgtaac
     5461 tttcgctgat aatgagtcag gttaccttgc aggtgtggct gcagcaaaaa caactaagac
     5521 aaaacaagtt ggttttgtag gtggtatcga atctgaagtt atctctcgtt ttgaagcagg
     5581 attcaaggct ggtgttgcgt cagtagaccc ttctatcaaa gtccaagttg actacgctgg
     5641 ttcatttggt gatgcagcta aaggtaaaac aattgcagcc gcacaatacg cagccggtgc
     5701 agatattgtt taccaagtag ctggtggtac aggtgcaggt gtctttgcag aggcaaaatc
     5761 tctcaacgaa agccgtcctg aaaatgaaaa agtttgggtt atcggtgttg accgtgacca
     5821 agaagcagaa ggtaaataca cttctaaaga tggcaaagaa tcaaactttg ttcttgtatc
     5881 tactttgaaa caagttggta caactgtaaa agatatttct aacaaggcag aaaaaggaga
     5941 attccctggc ggtcaagtga tcgtttactc attgaaggat aaaggggttg acttggcagt
     6001 aacaaacctt tcagaagaag gtaaaaaagc tgtcgaagat gcaaaagcta aaatccttga
     6061 tggaagcgta aaagttcctg aaaaataatg gatggaagtc atttcttagg aagcggccaa
     6121 gggccgcttt tttaagagtt gagacaaagt cattttgtct cagtaaagct tgctactaga
     6181 caaactagca agttttattg aaataaaata agactctgaa aggaagagca catggcacac
     6241 gaaaatgtca ttgagatgcg tgatattacc aaggtgtttg gtggatttgt tgccaacgac
     6301 aaaatcaaca tgcacctacg aaaaggtgaa attcatgcac ttttaggaga aaatggggct
     6361 ggtaagtcca cgctaatgaa catgttagca ggccttcttg aaccaactag tggtgaaatc
     6421 gcggtcaacg gtcaagttgt caatctcgac tccccatcta aagcagctag cttgggaatc
     6481 gggatggttc accagcactt tatgttggtt gaagccttca cagtggctga aaatatcatt
     6541 ttaggtagtg aattgactaa aaatggtgtg ctagatatcg ctggagctag caaagaaatc
     6601 aaggctcttt ctgaacgtta tggcttagct gttgaccctt ctgccaaggt agcaggtatc
     6661 tcagttggag cccaacaacg tgtagaaatt ttaaaaacac tttatcgggg ggctgatatc
     6721 cttatctttg acgaaccaac ggctgttttg actccatcag aaattgatga gttgatggct
     6781 attatgaaaa atcttgtcaa agagggaaaa tcaattatct tgattaccca caaattggat
     6841 gaaattcgag cagtttctga ccgtgttaca gttatccgtc gtgggaaatc aattgaaacc
     6901 gttgaaattg caggggctac caatgctgat ttggcggaaa tgatggtagg acgttctgtt
     6961 tcctttaaaa cagagaagca agcctctaaa ccaaaagaag tggttttgtc tatcaaagat
     7021 ttggtggtca atgaaaaccg tggtgttcca gctgttaaaa atctgtcctt ggatgttcgt
     7081 gctggagaga ttgttggtat tgcggggatt gatggaaatg gtcagtctga actgattcaa
     7141 gccattacag gtcttcgtaa ggttgaatct ggtagcattg agctaaaagg agattcaatt
     7201 gtaggcttgc acccacgtca gattacagaa ctaagtgttg ggcacgttcc agaagaccgt
     7261 caccgtgatg gcttgatttt ggaaatgatg atatctgaaa atattgccct tcaaacctac
     7321 tataaagaac cacatagtaa aaatggaatt ttgaactatt caaatattac ttcttatgct
     7381 aaaaagctga tggaagagtt tgatgttcgc gctgccagtg aattagttcc tgcagctgca
     7441 ctctcaggag gaaatcaaca aaaagcaatt attgctcgtg aaattgatcg agatcctgat
     7501 ctccttatcg ttagtcagcc aactcgtggg ttggatgtcg gtgccattga gtatatccac
     7561 aaacgcttga ttgaagagcg tgataatggc aaggctgtcc ttgttgtcag ctttgaattg
     7621 gatgagattt taaacgtctc agaccgtatt gccgttatcc acgatggtaa gattcaaggt
     7681 attgtatcac cagaaacaac caataaacaa gaacttggtg tcttgatggc tggtggaaac
     7741 ttgggaaagg agaagagtga tgtctaaaaa attacaacaa atttcggttc ccttgatttc
     7801 tgtattccta ggaattttac tcggagccat tgtcatgtgg atcttcggtt atgatgctat
     7861 ttggggctac gaagaattgt tctatacagc ctttggcagt ctgcgtggga ttggagaaat
     7921 cttccgtgct atgggtcctc tggtcttgat tggtcttggt tttgccgttg ccagtcgagc
     7981 tggtttcttt aacgtcggac ttcctggtca ggctttggca ggttggattc tcagtggttg
     8041 gtttgccctg tcgcatccag atatgccccg tcccttgatg attctagcaa ccatcgtgat
     8101 tgccttgatt gctggtggga ttgtcggagc gattccaggt attcttaggg cctatctagg
     8161 gacgtcagag gttattgtaa ccatcatgat gaactacatt gtcttgtatg tagggaatgc
     8221 ctttatccat gctttcccta aagacttcat gcaaagtaca gattcgacca ttcgtgttgg
     8281 ggctaatgca acctatcaga caccttggtt gactgagttg actggtaact cacggatgaa
     8341 tattggtatt ttctttgcca tcattgccgt tgcagttatt tggttcatgc tcaagaaaac
     8401 aactcttggt tttgaaatcc gtgcagttgg tcttaatcca catgcttcag aatatgctgg
     8461 tatttctgcc aagcggacta ttatcctatc tatgattatt tcaggtgcct tggcaggtct
     8521 tggtggagct gttgaaggtt tgggaacctt ccagaacgtc tatgttcaag gttcgtcatt
     8581 agctatcgga tttaacggaa tggcggttag tttgcttgcg gccaactcac caattggtat
     8641 actctttgca gccttcctat ttggcgttct ccaagttggg gctcctggta tgaatgcggc
     8701 gcaggtacca tctgagcttg tcagcattgt aacagcgtct attatcttct ttgtcagtgt
     8761 tcattacctt atcgaacgct ttgtcaaacc gaaaaaacaa gttaaaggag gtaagtaaag
     8821 atgtctatta taaccttgct ccccctcttg gtgtcttcta tgctgattta ctcagcacct
     8881 ctcatcttta caagtatcgg tggtgttttc tctgaacgtg gtggtgtggt aaacgttggc
     8941 cttgaaggaa ttatggttat gggtgccttt tctggagttg tctttaacct tgaatttgca
     9001 gaacaatttg gagcagcaac tccatggcta tccttgcttg tagcaggatt ggttggtagt
     9061 gttttctcta tcatccacgc agcagcgacg gttcatttcc gtgcagacca tgttgtcagc
     9121 ggtacggtat tgaacttgat ggcgcctgcc ttggctgttt tcttagttaa agttctttat
     9181 aacaaaggac aaaccgacaa cctaagtcaa acttttggac gctttgattt cccagtcttg
     9241 gcaaatatcc cagtgattgg tgatatcttc ttcaagtcaa ctagtctact tggttatctg
     9301 gcgattgcct tctcattcct tgcttggttt attctcttta agactcaatt tggtcttcgt
     9361 ctccgctctg tcggtgaaca tcctcaagca gcggatacct tgggaatcaa cgtctacaag
     9421 atgagatatt taggggttat tatttcaggt tttctaggtg gaattggcgg agcgatttat
     9481 gcgcaatcaa tctcagttaa cttctcagtg acaactattg ttggacctgg atttatcgcc
     9541 cttgctgcga tgatctttgg gaaatggaat ccaatcggtg ctatgctttc tagtctcttc
     9601 tttggacttt cacaaagttt ggctgttatc ggttctcaat tgccgttcct acaaggagtg
     9661 ccagcggttt atcttcaaat tgcaccttat gttttgacaa ttcttgtctt agcagccttc
     9721 tttggaaaag cagtcgcacc aaaagcagat ggtatcaact acatcaaatc aaaataagca
     9781 tacaaaaaaa cgtcagtcca atgactgaac tacaccccaa aagttagaca gaaaaaatct
     9841 aacttttggg gtgtttttat tatgaaatta acttatgatg ataaagttca gatctatgaa
     9901 cttagaaagc aaggatatag cttagagaag ctttcaaata aatttgggat aaataattct
     9961 aatcttaggt acatgattaa attgattgat cgttacggaa tagagttcgt caaaaaaggg
    10021 aaaaatcgtt actattctcc tgatttaaaa caagaaatga ttaataaagt ctgacatgaa
    10081 ggctggacta aagatagagt ttctcttgaa tacggcctcc caagtcgtac gatacttctt
    10141 aactggctag cacaatacag gaaaaacggg tatactattg ttgagaaaac aagagggaga
    10201 gtacctaaaa tgggacgtaa gccaaaaacg agacctgaag agaggacaga attagaatat
    10261 cttcaagcag aaaatgagta cctgagagcg gagaatgcca tcctaaaaaa gttaagagaa
    10321 ctccgattga aggaggaaaa agagaaagaa gaaggacaga aattgttcaa gaattaatga
    10381 ctgagttttc gttagttctt cttctaaaat ccattaaact agctcgttgg acctactact
    10441 atcacttgaa acagctagac aaaacagata aggaccaaga gcttaaagct gaaattcaat
    10501 ccatctttat cgaacacaaa ggaaattatg cttatcgccg ggttcattta gaactaagaa
    10561 atcgtgctta tctggtaaat cataaaagag ttc
//
LOCUS       DBEJKC010000063        10521 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.063, whole genome shotgun sequence.
ACCESSION   DBEJKC010000063 DBEJKC010000000
VERSION     DBEJKC010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10521
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.063"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            67..936
                     /locus_tag="ACL3G6_001775"
     CDS             67..936
                     /locus_tag="ACL3G6_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGR0546255.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            940..1896
                     /locus_tag="ACL3G6_001776"
     CDS             940..1896
                     /locus_tag="ACL3G6_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGR0546256.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            1896..2660
                     /locus_tag="ACL3G6_001777"
     CDS             1896..2660
                     /locus_tag="ACL3G6_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0546257.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            2660..3370
                     /locus_tag="ACL3G6_001778"
     CDS             2660..3370
                     /locus_tag="ACL3G6_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0546258.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            3678..4334
                     /locus_tag="ACL3G6_001779"
     CDS             3678..4334
                     /locus_tag="ACL3G6_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HGR0546259.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIISL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            4442..5537
                     /gene="prfB"
                     /locus_tag="ACL3G6_001780"
     CDS             join(4442..4513,4515..5537)
                     /gene="prfB"
                     /locus_tag="ACL3G6_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HGR0546260.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSYEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            5555..6247
                     /gene="ftsE"
                     /locus_tag="ACL3G6_001781"
     CDS             5555..6247
                     /gene="ftsE"
                     /locus_tag="ACL3G6_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HGR0546261.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            6240..7166
                     /gene="ftsX"
                     /locus_tag="ACL3G6_001782"
     CDS             6240..7166
                     /gene="ftsX"
                     /locus_tag="ACL3G6_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HGR0546262.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            7452..9632
                     /locus_tag="ACL3G6_001783"
     CDS             7452..9632
                     /locus_tag="ACL3G6_001783"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HGR0546263.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEV
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     NAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            9684..10499
                     /locus_tag="ACL3G6_001784"
     CDS             9684..10499
                     /locus_tag="ACL3G6_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGR0546264.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLSEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
BASE COUNT         3111 a         1866 c         2344 g         3200 t
ORIGIN      
        1 gagtataaga acctatcaaa aagtgaggga aaaccctcgg aattataaat agaaagagtg
       61 aatcttatgc tccaacaact cgtaaatggt ttgattctag gtagtgttta cgcgctgtta
      121 gccctaggat ataccatggt ttacggaatt atcaagctca tcaacttcgc ccatggtgat
      181 atttatatga tgggagcctt tatcggttat ttcttgatca attctttcca aatgaatttc
      241 tttgtagcgc ttattgtagc tatgctagcg acagctattc ttggtgtcgt gattgagttt
      301 cttgcttacc gacctttgcg ccactctact cgtattgctg ttttgattac ggctattggg
      361 gtttctttcc tattggagta tggaatggtc tatctggttg gtgccaatac ccgtgccttc
      421 cctcaagcga ttcaaacagt tcgatatgat ttgggaccaa ttagcttaac aaatgtgcag
      481 ttaatgattt tggccatttc cttgattttg atgattttgt tacaagtcat tgtccaaaag
      541 actaagatgg ggaaagccat gcgtgcagta tcagtagata gcgacgcggc gcaattgatg
      601 gggatcaatg taaaccgtac gattagcttt accttcgctt tgggttctgc tcttgcgggt
      661 gcggctggtg ttctgattgc tctttattat aactctcttg agcctttgat gggggttact
      721 ccaggtctta aatctttcgt tgccgcagta cttggtggta tcggaattat tcctggtgcg
      781 gctcttggtg gctttgtgat tggtctattg gaaacctttg cgacagcctt tgggatgtca
      841 gatttccgtg atgccattgt ttatggaatc ttgttgttga tcttgattgt ccgcccagct
      901 ggtatccttg gtaagaatgt gaaagagaag gtgtaaacga tgaaggaaaa tttaaaagtt
      961 aatattctat ggttactcct tttgttagct ggctatagct tgattagtgt actggtttca
     1021 gtcggagtac ttaatctatt ctatgtacag attttacaac aaattggaat taatattatt
     1081 ttggctgttg gtctcaactt aatcgttggt ttttcaggac aattttcact tggtcatgct
     1141 ggtttcatgg cgattggtgc ctatgcagca gctattattg gttctaaatc accaacctac
     1201 ggtgccttct ttggagctat gcttgtaggg gctttgcttt caggagcagt tgccttactt
     1261 gtcggcattc caaccttgcg cttgaagggg gactatcttg cggtagcaac tctgggtgtt
     1321 tctgaaatta tccgtatctt tatcatcaat ggtggaagtc ttacaaatgg tgcggcaggt
     1381 atcttaggga ttcctaactt tacaacttgg caaatggttt acttctttgt cgtgattaca
     1441 accattgcaa ccttgaactt cttgcgtagc ccaattggcc gttcaaccct ctctgttcgt
     1501 gaagatgaaa tcgctgctga gtcagttggg gttaatacga ctaaaattaa aatcatcgct
     1561 tttgtctttg gtgccattac tgcaagtatt gctgggtcac ttcaggcagg atttatcggg
     1621 tctgttgtac cgaaagatta caccttcatc aactcaatca acgttttgat tattgttgta
     1681 tttggtggac tcggttccat tacaggtgcg attgtttcgg ctattgttct gggaattttg
     1741 aatatgcttc tccaagatgt tgctagtgtg cgtatgatta tttacgcttt ggccttggta
     1801 ttggtaatga ttttcagacc aggtggactc cttggaacgt gggaactgag cctatcacgt
     1861 ttctttaaaa aatctaagaa ggaggaacaa aactaatggc attacttgaa gtaaaacagt
     1921 taaccaaaca ttttggtggt ctaacagctg ttggagatgt gactcttgaa ttgaacgaag
     1981 gggaactggt tggattaatc ggtccaaacg gagctgggaa aaccaccctt ttcaaccttt
     2041 tgaccggtgt ttatgaacca agcgagggaa cagtaaccct agatggtcac cttttgaatg
     2101 ggaaatcacc ttataagatt gcctctttgg gacttggacg tactttccaa aatatccgtc
     2161 tttttaaaga tttaacagtt ttagacaatg ttttgattgc ttttggaaac catcacaaac
     2221 agcatgtttt tactagtttc ttacgcttac cagcttttta caagagtgaa aaagaattaa
     2281 aggctaaagc tttggaattg ttgaaaatct ttgatttaga tggtgatgca gagactcttg
     2341 ctaaaaatct ttcctacgga caacaacgtc gtttggaaat tgttcgtgcc cttgctacgg
     2401 aacctaaaat tctcttctta gatgaaccag cagcaggtat gaacccacag gaaacagccg
     2461 aattgactga gttaattcgt cgtatcaaag atgaatttaa gattacaatc atgttgattg
     2521 aacacgatat gaatctggtc atggaagtaa cagaacgtat ctacgtactt gaatatggcc
     2581 gtttaattgc tcaaggaact ccagacgaaa ttaagaccaa taaacgcgtt atcgaagctt
     2641 atctaggagg tgaagcctaa tgtctatgtt aaaagttgaa aatctttctg tgcattacgg
     2701 tatgatccaa gcagtccgtg atgtaagctt tgaagttaat gaaggagaag ttgtttccct
     2761 tatcggtgcc aacggtgcag gtaagacaac tattcttcgc accttgtcag gtttggttcg
     2821 accaagttca ggaaagattg aatttttagg tcaagaaatc caaaaaatgc cagctcagaa
     2881 aatcgtggca ggtggtcttt cacaagttcc agaaggacgc cacgtctttc ctggcttgac
     2941 tgttatggaa aatcttgaaa tgggagcttt cttaaagaaa aatcgtgaag aaaatcaagc
     3001 taacttgaag aaggttttct cacgctttcc tcgtcttgaa gaacggaaga accaagatgc
     3061 agctactctt tcaggagggg aacaacaaat gcttgccatg ggacgcgctc ttatgtcaac
     3121 accaaaactt cttcttttag atgaaccatc aatgggactt gccccaatct tcatccaaga
     3181 gatttttgat atcattcaag atattcagaa gcaaggaaca accgtcctct tgattgaaca
     3241 aaatgccaat aaagcactcg caatctctga ccgaggatat gtattggaaa caggaaaaat
     3301 cgtcctatca gggacaggaa aagaactcgc ttcatcagaa gaagtcagaa aagcatatct
     3361 aggtggctaa aacaatccag tggattgttt tagtcggcag atgaagatta cgaagtaatc
     3421 atcaatatag tccgggggac ctttttagcc ggtagattga gattgcaaac aaatctgcat
     3481 ctacattgaa agcttaattt ctaataattg aaaaaatcga atgaaaagtt tcttaccttc
     3541 attcacagag ctcgatttta gagctctttt tgctagctta ttcatacttt tctaaatttt
     3601 gaaaaagaaa tgtaagcgtt tgatagattt gcaaaaagat tgtataatag ggataagaat
     3661 agaaaaggag aagtctcatg gcagttaaag attttatgac ccgcaaggta gtttatatta
     3721 gtccagatac aacagtatct catgcagcag atttgatgag agagcaagga ttgcaccgct
     3781 tgcctgttat cgaaaatgat caattggttg gtttggtgac tgagggaacc attgcacaag
     3841 caagtccatc taaagcaaca agtctttcta tctatgagat gaattatctt ctgaataaga
     3901 caaaagtaaa agatgtcatg attcgcgatg ttgtcactgt ctcaggctat gctagtctag
     3961 aagatgcaac ttatctgatg ttgaaaaata agattggtat tctccctgtc gtagataacc
     4021 atcaagtata cggagttatt actgaccgtg acgttttcca agcctttctt gaaattgcag
     4081 gttatggcga agaagggatt cgtgtacgct ttgttacaga agatgaagtt ggtgttcttg
     4141 gaaaaattat ttctttgatt gtagaagaaa atttgaatat ctcccataca gtcaatattc
     4201 cgcgtaagga tggtaaggtc attatcgaag tgcaaatcga tggatcaatt gatttaccag
     4261 ccttgaaaga aaaatttgaa gcaaatggta ttcaagtgga agaaatcgct cgcacttcag
     4321 caaaagtctt gtaagaaggg aagcccaaag gcttcttttt tcatgaaaag gggattagag
     4381 caaaagatgg aaagaaatga taaaatatgc tataatgaaa tgatgtaaaa aaggagtatt
     4441 tatggacatt tcagtaattc gtcagaaaat tgacgcaaat cgtgaaaaat tagcttcttt
     4501 cagggggtct ctttgacctc gaagggctag aggaagagat tgccatcttg gaaaacaaga
     4561 tgacagaacc tgatttttgg aacgataata ttgcggccca aaaaacgtcg caagaattga
     4621 atgaattaaa aaacacttac aataccttcc ataagatgga agagttgcag gatgaagtcg
     4681 aaattttatt ggattttttg gctgaagacg agtcagtgca tgatgaactg gtagcgcagt
     4741 tagccgaact tgataagata atgaccagct acgagatgac tctactcttg tcagaacctt
     4801 atgaccacaa caatgccatc ttggaaatcc atccaggttc tggtggtact gaggcgcagg
     4861 actggggtga tatgttgctt cgtatgtata ctcgttatgg taatgctaaa ggctttaaag
     4921 tggaagtgtt ggattaccaa gcaggtgatg aggctggtat taagtcggta actttatcat
     4981 ttgaagggcc taatgcctat ggtctcctca agtcagaaat gggtgttcat cgcttagtgc
     5041 gaatctcacc atttgactct gccaaacgtc gccatacctc tttcacatct gtagaagtga
     5101 tgccagaatt ggatgatact attgaagtgg aaatccgtga agatgatatc aagatggata
     5161 ccttccgttc aggtggtgcc ggtggacaaa acgtcaataa ggtttcaaca ggtgtacgtt
     5221 taacccacat tccaactgga attgttgtcc aatcaacagt ggatcgtacc cagtatggaa
     5281 atagagatcg cgccatgaag atgttgcagg ctaagctcta tcaaatggag caagagaaga
     5341 aggctgcgga ggtagattct ctcaaaggtg agaaaaagga gatcacttgg ggaagtcaaa
     5401 tccgttctta tgtcttcacg ccttatacta tggtaaaaga tcaccgaact agctatgagg
     5461 ttgctcaggt agataaggtt atggatgggg acctagatgg ttttatcgat gcttatctca
     5521 agtggcgaat tagctaagat agaaaggaac tcacatgtca attattgaaa tgagagatgt
     5581 cgttaaaaaa tacgacaacg gaacgactgc tctacgcggt gtttcggtta gcgttcaacc
     5641 gggggaattt gcttacatcg taggaccttc aggagcaggg aagtcaactt ttattcgttc
     5701 tctgtatcgt gaagtaaaaa tcgataaagg aagtctatca gttgctggtt ttaatctggt
     5761 taagatcaaa aagaaagatg tcccgcttct acgtcgtagt gttggggttg tcttccaaga
     5821 ttataaactg ttaccaaaga aaactgtcta tgaaaatatt gcttacgcta tggaagtaat
     5881 cggggaaaat cgccgtaata tcaaaagacg agtgatggaa gttttggact tggttggatt
     5941 gaagcataag gttcgttctt tcccaaatga actctcaggt ggggagcaac agcggattgc
     6001 gattgcgcgt gcaattgtaa ataatcccaa agtattgata gctgatgagc caacaggaaa
     6061 tctggatccg gataattcat gggaaattat gaatctcttg gaacggatta acctacaagg
     6121 aacaactatt ttgatggcga ctcataatag ccagattgta aataccttgc gccaccgtgt
     6181 cattgccatt gaaaatggcc gtgtcgttcg tgacgaatca aaaggagagt atggatacga
     6241 tgattagtag attttttcgc catttatttg aagccttaaa aagtttgaaa cgaaatggtt
     6301 ggatgacagt agctgctgtc agttcagtca tgattacttt gaccttggtg gcaatatttg
     6361 catctgttat tttcaataca gcgaaactag ctacagatat tgaaaataat gtccgtgtag
     6421 tagtttatat ccgaaaggat gtggaagata atagtcagac aattgaaaaa gaaggtcaaa
     6481 ctgttacaaa taatgactac cacaaggtat atgattcttt gaagaacatg tctacggtta
     6541 aaagtgttac cttttcaagt aaagaagaac aatatgaaaa attaaccgag ataatgggag
     6601 ataactggaa aatctttgaa ggagatgcca atcctctcta tgatgcctat attgtagagg
     6661 caaacactcc aaatgatgta aaaactatag ccgaagatgc taaaaaaatt gaaggtgtct
     6721 ctgaggttca agatggcggt gccaatacag aaagactctt caagttagct tcatttatcc
     6781 gtgtttgggg actagggatt gctgctttgt taatttttat cgcagttttc ttgatttcaa
     6841 ataccattcg tattaccatt atttcccgca gtcgcgaaat tcaaatcatg cgcttggtcg
     6901 gagctaaaaa cagttatatc cgtggaccgt tcttgttaga aggagccttt atcggtttat
     6961 tgggagctat cgcaccatct gttttggtct ttattgttta tcaaattgtt taccaatctg
     7021 tcaacaaatc gttggtaggg caaaatctat ccatgattag tccagattta tttagtccgt
     7081 tgatgattgc cctactattt gtgattgggg ttttcattgg ttcattggga tcaggaatat
     7141 ccatgcgccg attcttgaag atttaggtaa aatagctgct tttatgagga gattgtaaaa
     7201 tctccttttt tgctacaaga gtttttgaaa agagatgcgc agaagaaaag agcttccaaa
     7261 gaagtccccc agagaagact tcttgatggc taatttgaac ttgaaatttg gcgcactaga
     7321 aattttttag aaaaaagtgt aattttttta taaaagcctt tacaaaaaaa attaaagtgg
     7381 tataattaaa tcatagaaag tgcaaacgtt ttcgtaaaac gtttgcctaa ataaaaataa
     7441 aggagatttg aatgatgaaa gatacattca aaaatgtctt gtctttcgaa ttttggcaaa
     7501 aattcggtaa ggctttgatg gtagttatcg cggttatgcc ggctgctggt ttgatgattt
     7561 caatcggtaa gtctatcgtg atgattaacc caacctttgc accacttgtc atcacaggtg
     7621 gaattcttga gcaaatcggt tggggggtta tcggtaacct tcacattttg tttgccctag
     7681 ccattggagg aagctgggct aaagaacgtg ctggtggtgc tttcgccgct ggtcttgcct
     7741 tcatcttgat taaccgtatc actggtacaa tctttggtgt atcaggcgat atgttgaaaa
     7801 atccagatgc tatggtaact actttctttg gtggttcaat caaagttgct gattacttta
     7861 tcagtgttct tgaagctcca gccttgaaca tgggggtatt cgtagggatt atctcaggtt
     7921 ttgtaggggc aactgcttac aacaaatact acaacttccg taaacttcct gatgcacttt
     7981 cattcttcaa cgggaaacgt ttcgtaccat ttgtagttat tcttcgttca gcaatcgctg
     8041 caattctact tgctgctttc tggccagtag ttcaaacagg tatcaataat ttcggtatct
     8101 ggattgccaa ctcacaagaa actgctccaa ttcttgcacc attcttgtat ggtactttgg
     8161 aacgtttgct cttgccattt ggtcttcacc acatgttgac tatcccaatg aactacacag
     8221 ctcttggtgg tacttatgac attttaactg gtgcagctaa aggtactcaa gtattcggtc
     8281 aagacccact atggcttgca tgggtaacag accttgtaaa ccttaaaggt actgatgcta
     8341 gtcaatacca acacttgtta gatacagtac atccagctcg tttcaaagtt ggacaaatga
     8401 tcggttcatt cggtatcttg atgggtgtga ttgttgctat ctaccgtaat gttgatgctg
     8461 acaagaaaca taaatacaaa ggtatgatga ttgcaacagc tcttgcaaca ttcttgacag
     8521 gggttactga accaatcgaa tacatgttca tgttcatcgc aacacctatg tatcttgttt
     8581 actcacttgt tcaaggtgct gccttcgcta tggctgacgt cgtaaaccta cgtatgcact
     8641 cattcggttc aatcgagttc ttgactcgta cacctattgc aatcagtgct ggtattggta
     8701 tggatatcgt taacttcgtt tgggtaactg ttctctttgc tgtaatcatg tactttatcg
     8761 caaacttcat gattcaaaaa ttcaactacg caactccagg gcgcaacgga aactacgaaa
     8821 ctgctgaagg ttcagaagaa accagcagcg aagtgaaagt tgcagcaggc tctcaagctg
     8881 taaacattat caaccttctt ggtggacgtg taaacatcgt tgatgttgat gcatgtatga
     8941 ctcgtcttcg tgtaactgtt aaagatgcag ataaagtagg aaatgcagag caatggaaag
     9001 cagaaggagc tatgggtctt gtgatgaaag gacaaggggt tcaagctatc tacggtccaa
     9061 aagctgacat tttgaaatct gatatccaag atatccttga ttcaggtgaa atcattcctg
     9121 aaactcttcc aagccaaatg actgaagtac aacaaaacac tgttcacttc aaagatctta
     9181 ctgaggaagt ttactcagta gcagacggtc aagttgttgc tttggaacaa gtaaaggatc
     9241 cagtatttgc tcaaaaaatg atgggtgatg gatttgcagt agaacctgca aatggaaaca
     9301 ttgtatctcc agtttcaggt actgtatcaa gcatcttccc aacaaaacat gcttttggta
     9361 ttgtgacgga agcaggtctt gaagtattgg ttcacattgg tttggacaca gtaagtcttg
     9421 aaggtaaacc atttacagtt catgttgctg aaggacaaaa agttgcagca ggagatctcc
     9481 ttgtcacagc tgacttgaat gctatccgtg cagcaggacg tgaaacttca acagtagttg
     9541 tcttcacaaa tggtgatgca attaaatcag ttaaattaga aaaaacaggt tctcttgcag
     9601 ctaaaacagc agttgctaaa gtagaattgt aatatacttg aggttggaag ctgtattcca
     9661 acctcttatt ttgggagaaa agaatgaaat ttttaacact caatactcat agttggatgg
     9721 agaaagaagc agaggaaaaa ttccagattt tgcttgaaga tattcttgaa aaggactatg
     9781 atttgatttg tttccaagaa attaatcagg agatgacctc gtcagaggtg gaggttaatg
     9841 acctttatca agctttgcca gcagctgagc ctattcacca agatcactat gttagactct
     9901 tggttgaaaa gttatctgag caagggaaaa attactactg gacctgggcc tataaccata
     9961 tcggctatga ccgctaccac gaaggtgtgg ctatcttgtc taaaacacct attgaagcca
    10021 gagaaatttt ggtttcagat gtggatgatc caacagacta tcatactcgc cgtgttgccc
    10081 tagctgaaac tgtagtcgat ggcaaggagc tagcagttgc cagtgttcat ctctcttggt
    10141 gggataaagg ttttcaagaa gaatgggcac gatttgaggc tgtcttgaaa aaattgaaca
    10201 agccactttt actagctgga gattttaaca acccagcagg tcaggaaggt taccaagcta
    10261 ttttagctag tccattaggc ttacaagacg catttgaagt tgctcaagag aaaagtggta
    10321 gctatactgt tccgcctgaa attgatggct ggaaagggaa cactgaaccc cttcgaatcg
    10381 attatgtctt tactaccaaa gagttagcgg tggaaaattt acatgtcgta tttgatggta
    10441 acaagagtcc acaagtgagt gatcactatg gcttgaatgc tatgttaaac tggaaataat
    10501 aactgaaaag aggttggaac t
//
LOCUS       DBEJKC010000064        10375 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.064, whole genome shotgun sequence.
ACCESSION   DBEJKC010000064 DBEJKC010000000
VERSION     DBEJKC010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10375
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.064"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..304
                     /locus_tag="ACL3G6_001785"
     CDS             <1..304
                     /locus_tag="ACL3G6_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0546265.1"
                     /translation="PMTYEETMTSDFFEAWFQKFFLPTLTTPSVIIMDNARFHRMGKL
                     ELLCEEFGYKLLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALLSCSCFN"
     gene            204..650
                     /locus_tag="ACL3G6_001786"
     CDS             204..650
                     /locus_tag="ACL3G6_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0546266.1"
                     /translation="MRKHGLISKSTSKRYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRVFVTNTGKTVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(788..2092)
                     /gene="eno"
                     /locus_tag="ACL3G6_001787"
     CDS             complement(788..2092)
                     /gene="eno"
                     /locus_tag="ACL3G6_001787"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-displayed alpha-enolase"
                     /protein_id="HGR0546267.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2256..2702
                     /locus_tag="ACL3G6_001788"
     CDS             2256..2702
                     /locus_tag="ACL3G6_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HGR0546268.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2699..3814)
                     /locus_tag="ACL3G6_001789"
     CDS             complement(2699..3814)
                     /locus_tag="ACL3G6_001789"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0031388 - organic acid phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HGR0546269.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASDQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3823..4152)
                     /locus_tag="ACL3G6_001790"
     CDS             complement(3823..4152)
                     /locus_tag="ACL3G6_001790"
                     /inference="COORDINATES: protein motif:HMM:NF019887.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HGR0546270.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(4097..4468)
                     /locus_tag="ACL3G6_001791"
     CDS             complement(4097..4468)
                     /locus_tag="ACL3G6_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HGR0546271.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4527..5960)
                     /gene="glgA"
                     /locus_tag="ACL3G6_001792"
     CDS             complement(4527..5960)
                     /gene="glgA"
                     /locus_tag="ACL3G6_001792"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HGR0546272.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHIHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWLAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(5957..7096)
                     /gene="glgD"
                     /locus_tag="ACL3G6_001793"
     CDS             complement(5957..7096)
                     /gene="glgD"
                     /locus_tag="ACL3G6_001793"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HGR0546273.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7086..8228)
                     /locus_tag="ACL3G6_001794"
     CDS             complement(7086..8228)
                     /locus_tag="ACL3G6_001794"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HGR0546274.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8218..10146)
                     /gene="glgB"
                     /locus_tag="ACL3G6_001795"
     CDS             complement(8218..10146)
                     /gene="glgB"
                     /locus_tag="ACL3G6_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HGR0546275.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPNVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLICIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3143 a         2285 c         1834 g         3113 t
ORIGIN      
        1 tccaatgact tacgaagaga cgatgacgag cgactttttt gaagcttggt ttcagaagtt
       61 tttcttacca acattaacca caccatcggt tattattatg gataatgcaa gattccatag
      121 aatgggtaag ttagaactct tgtgtgaaga gtttgggtat aaacttttac ctcttcctcc
      181 ctactcacct gagtacaatc ctattgagaa aacatgggct catatcaaaa agcacctcaa
      241 aaaggtatta ccaagttgca atacctttta tgaggctctt ttgtcttgtt cttgtttcaa
      301 ttgactatat aaattgtcta agcgaaacaa ccgataagaa ttggcacaaa agcgaccgtg
      361 tttttgttac caatacagga aaaacagttc atagttctat cttgagcaag tctctccagc
      421 gagcaaacga acgccttaaa aaaccaattc ccaaacatct gtcccctcac atcttcagac
      481 acaccactat tagcatctta tcagaaaata aaattccttt aaaaacaatc acggacaggg
      541 ttggtcattc cgactctgaa gtcactactt ccatctacac ccacgtcaca aagaacatga
      601 aagatgaagc aatcaatgta ctggataaag ttatgaaaaa gattttttaa aaagttttgc
      661 cccttttttg tcctctaaat acaaaaatag cccttcggat aaaatccgag gggctagaaa
      721 cgttgttaaa tcaacggccg aacttttgaa tttcatggtt cgggataaaa tagttcactg
      781 aactatttta ttttttaagg ttgtagaatg atttcaatcc acgatattca gctacttcac
      841 caagttggtc ttcgatacga agcaattggt tgtatttagc gatacggtct gtacgtgaaa
      901 gtgaaccagt cttgatttgt cctgcgttag ttgcaactgc aatatcagcg attgttgaat
      961 cttcagtttc acctgaacgg tgtgatacaa cagcagtgta accagcttct ttagccattt
     1021 cgatagcttc aaaagtttca gtaagagtac cgatttggtt aactttgata aggattgagt
     1081 tagcagcacc ttcttggata ccacgtgcaa ggtagtcagt gtttgttacg aagaagtcgt
     1141 caccaacaag ttgtactttc ttaccaagac gttcagtaag agctttccaa ccatcccagt
     1201 cgttttcatc cataccatct tcaatagtga tgattgggta tttgttaacc aattcttcaa
     1261 ggtagtcgat ttgttctgca gatgtacgaa cagcagcacc ttcaccttca aatttagtgt
     1321 agtcgtaaac tttacgttct ttatcgtaga attctgatga agcacagtca aatccgataa
     1381 atacgtcttt acctggtaca tatccagcag cttcaatcgc agcaaggata gtttcaacac
     1441 catcttcagt tccttcgaaa cgaggagcga atccaccttc gtcacctacg gcagtttcca
     1501 aaccacgtga tttaaggatt ttcttaagag cgtggaagat ttcagcaccg taacgaaggg
     1561 cttctttaaa tgttggcgca ccaactggca agatcatgaa ctcttggaaa gcgattggag
     1621 cgtcagagtg agaaccaccg ttgatgatgt tcatcattgg agttggaaga actttagtgt
     1681 tgaatccacc aaggtagctg taaagtggga tttcaaggta gtcagcagca gcacgagcta
     1741 cagcgataga cacaccgagg attgcattcg cacccaattt acctttgtta ggagtaccgt
     1801 caagtgcgat catagcacgg tcaatagctt gttgatcacg tacatcgtag ccaatgatag
     1861 cttcagcaat gatgttgttt acgttgtcaa cagctttttg tgtaccaaga ccaccgtaac
     1921 gagatttgtc accgtcgcga agttcaactg cttcgtgttc accagtagaa gctcctgatg
     1981 gaaccatacc acgtccgaaa gcacctgatt cagtgtaaac ttctacttca agtgttgggt
     2041 taccgcgtga gtctaggact tcgcgagcgt aaacatcagt aataattgac attttttact
     2101 ctccttatga gttaaatttt ttacacctct ataatacctt aaaacccctc ctttttcaag
     2161 aaaaaacgtt atctttgtgc aacttttcct taactttata aagtaatcgc tttcttttgt
     2221 ctgttttatt ctaactttta tgatatactg ttttcatgac agatttatca aaacaattac
     2281 ttgaaaaagc tcatggtggg ttaaaaataa atccggatga acaaagacgc tatcttggta
     2341 cttttgagga aagagttctt ggatatgtag atattgacac agcaaatagc cctcagttag
     2401 aaaaaggctt tttatttatt ttagaaaacc ttcaggaaaa agcagagcca ctatttgtga
     2461 agatttcacc aactatcgaa tttgataagc aagttttcta cttaaaagaa gcaaaagaaa
     2521 ctgatagtca agccaccata gtatctgaag agcatattac ttctcctttt ggcctggtta
     2581 ttcatagcaa tgcaccagtt caagtagaag aaaaagacct tcgacttgct tttccaaaac
     2641 tttgggaagt taaaaaggaa gaaccagcca aaacatcctt atggaagaaa tggtttagct
     2701 aaatcttgca catatttaat aagtgcccaa tattggcagc cgtgcgctcc agatagagac
     2761 tggcattttt caaactatct tctaaaggtt cacttttctc caaaatagaa aagacagctt
     2821 ggatattttc aaatggtagg ggaggtaaat cttcagcaag actaccgcaa atagcaataa
     2881 caggaactcc aacaggggtt ctttttgcaa cacctatagg cgctttccca gcaaagcttt
     2941 gactatcaag tcttccttct ccaacaacaa ccaagtcagc atctgaaact ttcttatcaa
     3001 agttgattaa gtccaagcag gtatcaattc cagacacgat acttgcctga gcaaaggcac
     3061 acaaaccacc agcaaggcct ccacctgctc ctgctccttt aatttctaat gttgcaggtg
     3121 agaatttttc ataaaaatct tggatcgcct gatctacgac tgcaaacata gtcggatgta
     3181 gacctttttg attgccaaaa gtgtaagtcg caccttgatg accacataag ggactcacga
     3241 catctgctag aatatgaatt tgaacacctt caggaatttt atagcaattt tctgttgaaa
     3301 cagaagctaa gtttaataag gattgatcgg aagcaggcaa gacatttcca tccctatcat
     3361 aaaattgata acctaaacca gcagcaatcc ccagtcctcc atcattactg gccgtgccac
     3421 caacaccgat ataaatatct ttaatccctt tagaaatgag atggagaatc aactctccaa
     3481 taccacaagt ttggatttga agtggatttc gtttctctag cggaattttt ccaagaccaa
     3541 ccaagtcagc tacttcaaat agtgccagtt cccctttttg aaaatagcgc atggcttctt
     3601 tttgtccaaa agggtctgtc acttggatcc atttttcttt taggtcaaga gaatgtcgga
     3661 tagcatctac agtaccttct cccccatcac caacagggca gaggagacat tctacatctg
     3721 ctatcgattg ttggaagcct ctttttattg cttcagctac ctgttgagct gtcaagcttt
     3781 ccttaaacga atccggtgca attacaatct tcatattttc cctcattcta aacagtcaat
     3841 caaaggaaga acttctaaaa aatccctctt gtcaacatga tgtggtattt cttttttgag
     3901 catttctttg gaacaaaagg cgattcctaa ctccgccgac ttcaacatta atagattatt
     3961 gaccccatca ccgattgcca ccgttctttc tttagaaagt tttagtttct ttctccattt
     4021 ttccagagtt tcttttttga cctggggact tataatttgt ccaactaatt ttcctgttaa
     4081 aagaccttct ttgacttcaa gctggttggc agtgaaatag gcaataccaa gggattttgc
     4141 taatctctcc aactattggt gtaaatccac cagacaccag accaactagg atgccattct
     4201 tttggagaat agagatgaac tctgggacat ttagcgatag atgaattgag ttgaagacgt
     4261 tatcaaagac caaaatagga agaccttcca acaaggacac tctttttctt aaactgcttt
     4321 caaagaccaa ctctcctcgc attgctcgac ttgtaatctg cgaaatttcc gcctcatgac
     4381 ctgcctctct ccctaaaaga tcaatcactt cttctaggat taaggttcca tctacatcca
     4441 aaacacacaa gccttttact tgagacatca gttctcctct ctaaacagcc taaaaatcgt
     4501 atgaagtcat catacgattt tatctattaa ttaactaaac tatggtacaa gtcaaggtat
     4561 gacttgcagg ctgtatccca tgagaagtca ctctccatag cttgtttttg taggtttctc
     4621 caaatgtctg gatggtttct atacaagtcc aatgctgttt ggaaagtcca atttaaccaa
     4681 taaggagata gattgtcaaa gctaaagcca gtaccgcttc cttcgattgg attgaaagcg
     4741 cgaactgtat ctcgcaagcc tccaacttca tggaccaatg gcaaggttcc ataacgcata
     4801 gccatcattt gagacaagcc acacggttca aaacgacttg gcatgaggaa gaggtcacaa
     4861 gcagcgtaga tttcctgagc aagtttgaca tcaaaagtga tatttgttga tagcttgtct
     4921 gggtaaatct gagccaacca tgagaaagct ccttcaaagg ctggatcgcc agttcccaaa
     4981 agaacaatct gaacatcttc ttgcaagata tggtgaagac tttcgaccac cacatcaaaa
     5041 cctttttgac gtgtcaaacg agaaacaatt cccaccagtg gaacgtctgc tctaacaggc
     5101 aagccaactc tttcttgcaa ttttgcctta tttttggctt tcccagacaa atcttcctga
     5161 ttgaaatgat agtctaaaag agcatccgtc tgaggattat aaagatcagc atcaatccca
     5221 ttcacgatac cagatacttt accagactcc attttaagaa tctgatccaa attacatcca
     5281 aactgactag tcataatttc atgagcatag ctaggtgaaa cggttgaaac acggttcgca
     5341 tagagaatac ctgccttcat ccagttcaga cagttgttcc atcgaagggt gccatcagcg
     5401 taacgttcaa ggccaactcc aaacaaatca cccaacattc cttctgaaaa ttgtccttgg
     5461 aattctaaat tatgaatggt taaaactgtt tcaatgtcct cataggcttg aatccaacgg
     5521 tatttttcct tcaacaagaa aggaatcata gctgtatggt agtcatgaat atggagaaga
     5581 tcaggaataa agtcaatcct ttccatagcc tcaatggcag ccagttggaa aaaggcaaag
     5641 cgttctccgt catcaaaatc accgtaaaca tgaccacgga agaaataata ttgattgtca
     5701 ataaagtaga aggttacacc atttaatact gttttcttaa ttccacaata ctgtctgcgc
     5761 caaccaacgc tcacctcaaa atgaagcaca tcttcaatct gatttccaaa tttagcctct
     5821 accatatcat agtagggtaa aatcactgca acttcgtgcc cagcttttac cagtgatttt
     5881 ggaagagcgc caatgacgtc tcccaaacca cctgtttttg aaaagggtgc accctctgct
     5941 gctacaaata aaattttcat gaatgaatat cctctgttac tttagcacct ttcttaacca
     6001 caactggatg ttctgcagtt cctcgaatca caacaccagg ctcaacttca acccctttgt
     6061 ccaagatagc atattcgacc tgagcccctt ctccaataac aacacgaggg aagagcaggc
     6121 tatctttaac caagctatcc ttatggacat gaatattacg tgatagaaca gaattagcta
     6181 cttgaccttc aataatacta ccagaggcaa actgagaagt gcttacctta gatgtattag
     6241 catagtaagt tggctcttcg tttttgacct ttgtataaat cttttggttt ggtgagaaaa
     6301 gagaatagaa tttttgtgat tcaagcatat cgatattcgc ttgataataa gatttaacag
     6361 agtgaatatt ggctagatag cccgtgtact cgtaggcgaa agctccctct tttacagcca
     6421 aatcccgtaa aacatagcgc aatttctttg gatgttcttt tttagcttct tcttccaagt
     6481 gttcaatcaa ccaaggtgta tcaacgacaa agatatctgt agacatattg aacgtttcag
     6541 ctgttgactt gctatcaaag agtttatgag aaagaacatg gtctgtttca tctacatcca
     6601 agattgcatt tacttctgaa atatctttct tagctagttt tttataaact acagtgatag
     6661 gctcttttgt tgtactatgt aggtggaaaa cttggttcaa atcaatgtta ataagaacat
     6721 cgcagttgag ggcaaccgtt tggtttgagc cagaacgttt caaataagta agaagctgtt
     6781 ggtagtattc ttttccaact gtactacttt ctacacgggt attgtaaatt cctagatagt
     6841 aatgactaag aagggttgat aagccccact cgcgtcctga acgaatatgg tcaaatactg
     6901 agctgatatt atcctgctgg aaaataccaa agacactacg aacacctgca ttagcaaggc
     6961 ttgaaagtgg gaagtcaatc aaacgatatt tcccaccaaa tggcaaactt gctactggac
     7021 ggtggtccgt caatgtcgac atattgtgaa aaccaactgt atttcctaaa atggcagaat
     7081 atttatcaat cttcatctgt tgctaccccc actacttcat tatatcctac aacttgtact
     7141 tcatctgttc catcaatttc gacaccgtca gaaataatcg caccttcacc aataatggca
     7201 cgtttaatct tagctccttg accaatgata gctccactca tgataactga atcaaggact
     7261 tccgctcctt cgcgaacttg cgcgcctgtt gaaaggatag aatgtttaac agttccatca
     7321 acgaaacatc cgtctacaac taatgagtct tccacatgag catttgcccc gaggaagttt
     7381 ggtggtgaaa tcaagtttct tgagtaaatc ttccattgac ggttacgact atccaaggca
     7441 ttttctggag aaatatactc catgttcgct tcccaaagtg actcaatagt accaacatct
     7501 ttccaataac cactaaattc gtaagcataa acactttcac ctgactcaag gtaatttgga
     7561 atgacatttt tcccaaagtc tgacatgcca accttgctct tttcagcagc gactaacata
     7621 ttacgaaggc gttgccaatc aaaaatgtag attcccatag aagcttttgt agatttaggt
     7681 tgagctggtt tttcttcaaa ttcaacaata cgattgttag catctgtgtt catgatacca
     7741 aaacggcttg cttctttaag agggacgtct aaaactgcta ctgtcaagct ggcattatta
     7801 tccttatgag actggagcat atcatcatag tccattttgt agatgtgatc cccagacaaa
     7861 atcaagacat actcaggatt gacactgtcg atatagtcga tattttggta aatagcgtga
     7921 ctagtcccct caaaccaacg atttccttca cttgcagaat aaggttgaag aatagagaca
     7981 cctgaattga taccgtctag tccccagctt gaaccattcc caatatggtt gttgagagca
     8041 agtggttgat actgtgtaac gaccccaaca ttatgaatcc ctgagttggc acagtttgat
     8101 agggcaaagt caatgatacg gtagcgccca ccaaattgca cagctggttt tgcgatgctt
     8161 tgagtgagtt taccgagacg agttccttgc ccaccagcaa gaatcaaagc taacatttca
     8221 tttttcattt tctactcctt tttggttttt atttgtgacg gttttagtag atttcaagcg
     8281 acgtttgatt ttccatacac ttgctcccat agccggtaga gtaaaggtta aggtctgctc
     8341 ataatctttc catagtcctt cttgcgtttg aacagtttga ttatgttctt tccaaacgcc
     8401 tccccactct tccaactcag tattccatac ttcttcgtaa attcctgcaa cgggtagtcc
     8461 gattgtaaaa tctttccgct caacaggtac catgttaaag atacagatta acatttctcc
     8521 ctttttaccc ttacgaataa aggaaagaac actctggtct cgattatccg catcaatgat
     8581 ttcaatacca tcatagctgg tatcgatttc ccacagacag cgatgatctt tgtaaaactg
     8641 gtttagctga gaagtgaaat acttcatctt agcattcatt gggtcttcta ggttagacca
     8701 ttccaactgt tcttcagatt tccattctag gaattgaccg tattcgctac ccatgaagag
     8761 caatttctta ccagggtgac aaatttggta cgtatagaga ttgcgcaagc ctgcgaattg
     8821 attgtaacga tctccccaca tcttatgcat catactcttc ttgccatgaa ccacttcatc
     8881 gtgcgagaat ggcaagagat aattctcctt gaaaacatac ataaagctga aagtcaccag
     8941 gttaaagtca tatttacgat agatcggatc ttcttcgtag aaacggagga tatcattcat
     9001 ccagcccatg ttccatttgt agtcaaatcc tagaccacca atctctttca ttcccgtaat
     9061 cttggtcgca gacgaacttt cttctgcaat catcatcaca tttggatatt ctaacttaat
     9121 aacctcattc aagcgctgaa ggaaataata accttcatag ttgagatttc cgccatcttt
     9181 attaggtgtc catggagcat catcatagtc caaatagagc atgttgctaa cagcatccac
     9241 acgaatacca tccaaatgat agacatcaat ccaatgctta atgcaagaaa ttaagaagga
     9301 ctggacttca ttttttccaa ggtcaaaatt aagggcaccc caaccatggt tatgagcctt
     9361 attatggtct tggtattcaa aagtcggtgt cccatcataa taggctaagg catcatcgtt
     9421 gatggtaaag tgacctggta cccagtccac aataacccca atattatggg tatgacactc
     9481 ctcgacaaaa tcttgaaact cctctggtcg gccataagca tgctctaaag cgaagtaacc
     9541 cataagctga tacccccaac tcaagcccaa aggatgggac atcaagggca taaactcaat
     9601 atgagtatag ttcatttcaa cgagataagg aatgagttca tccttgagct gggcaaaact
     9661 ataaggactg ccatcagaat ttcttttcca tgatccagcg tgaacttcat aaatattgac
     9721 aggacgctct tcaaagcccc aacgttttct tcgtgccagc caaagtccat ccttccattt
     9781 cttctcagga agctctgtta agattgcccc tgttcctgga cgagcctcat acctgacagc
     9841 aaaagggtca atcttcatca gttgatgacc attttgacgt gtgacatgat atttgtaaat
     9901 atgcccttct tgagccatat tggtaaagac ttcccagacc ccaaaatcat ttcttaccat
     9961 tggaatctga ttttcaatcc agttggtaaa atcaccaacc aagtgaacag cctgagcatt
    10021 aggtgcccaa acacggaagg tatagccatg ctctccattt agttcttccc tatgtgctcc
    10081 tagataatgt tggagataaa aattttcacc cgtcataaag gtttttaatg cttctctatt
    10141 atccatatac tccccttctc ctgtaagcgt tttctatgtt tttattatac taccttttta
    10201 gagaagattc aagtaaatta ctatacttct ttaattattt tgaaaatcta caacaagttc
    10261 acttactcgt tcaattgtaa atcaatattt tttcaaaaaa ttgcgaaaac gcctttcttt
    10321 ttctactata gtgaaatgaa ataaaacatg cgcaaatcga ttaaggactt taatc
//
LOCUS       DBEJKC010000065        10344 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.065, whole genome shotgun sequence.
ACCESSION   DBEJKC010000065 DBEJKC010000000
VERSION     DBEJKC010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10344
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.065"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..141)
                     /locus_tag="ACL3G6_001796"
     CDS             complement(<1..141)
                     /locus_tag="ACL3G6_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HGR0546276.1"
                     /translation="MAYSIDFRKKVLSYCERIGSITEASHVFQISRNTIYGWLKLKEK
                     TGE"
     gene            complement(355..2118)
                     /locus_tag="ACL3G6_001797"
     CDS             complement(355..2118)
                     /locus_tag="ACL3G6_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HGR0546277.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            complement(2127..2717)
                     /locus_tag="ACL3G6_001798"
     CDS             complement(2127..2717)
                     /locus_tag="ACL3G6_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HGR0546278.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            complement(2815..3306)
                     /gene="rocS"
                     /locus_tag="ACL3G6_001799"
     CDS             complement(2815..3306)
                     /gene="rocS"
                     /locus_tag="ACL3G6_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HGR0546279.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            complement(3383..4075)
                     /locus_tag="ACL3G6_001800"
     CDS             complement(3383..4075)
                     /locus_tag="ACL3G6_001800"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HGR0546280.1"
                     /translation="MKIGIIAAMPEELAHLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLAFLKALD"
     gene            complement(4092..4406)
                     /gene="macP"
                     /locus_tag="ACL3G6_001801"
     CDS             complement(4092..4406)
                     /gene="macP"
                     /locus_tag="ACL3G6_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HGR0546281.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            complement(4418..4963)
                     /locus_tag="ACL3G6_001802"
     CDS             complement(4418..4963)
                     /locus_tag="ACL3G6_001802"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0546282.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            complement(4973..6352)
                     /gene="glmU"
                     /locus_tag="ACL3G6_001803"
     CDS             complement(4973..6352)
                     /gene="glmU"
                     /locus_tag="ACL3G6_001803"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002899862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HGR0546283.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRCRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPRNQ"
     gene            6486..7286
                     /locus_tag="ACL3G6_001804"
     CDS             6486..7286
                     /locus_tag="ACL3G6_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HGR0546284.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSIWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            7381..8223
                     /locus_tag="ACL3G6_001805"
     CDS             7381..8223
                     /locus_tag="ACL3G6_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HGR0546285.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYSLNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNTGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            8223..8705
                     /locus_tag="ACL3G6_001806"
     CDS             8223..8705
                     /locus_tag="ACL3G6_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HGR0546286.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            8705..9325
                     /locus_tag="ACL3G6_001807"
     CDS             8705..9325
                     /locus_tag="ACL3G6_001807"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR0546287.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPADRILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(9578..9673)
                     /locus_tag="ACL3G6_001808"
                     /pseudo
     CDS             complement(9578..9673)
                     /locus_tag="ACL3G6_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            10086..10344
                     /locus_tag="ACL3G6_001809"
                     /pseudo
     CDS             10086..10344
                     /locus_tag="ACL3G6_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
BASE COUNT         3177 a         2177 c         1797 g         3193 t
ORIGIN      
        1 ctctcctgtt ttctctttta gctttaacca gccataaatg gtattacgtg agatttggaa
       61 aacgtgtgat gcttctgtta tactacctat tcgctcacaa taagagagaa cttttttacg
      121 aaaatctatt gaatatgcca taagaagatt ataccacatt gtgtactatt tttggttcat
      181 tttactatat tttataagtt atagtgtagc attccaactt caaagcacta taaagtaaat
      241 tgaaacaaga acaatacaaa caattctcgt aaacggattg caaccacaaa aaagcaagca
      301 ttcacaagaa tacttaccta tcatgggagg aacaaccgtt cctctttttt attactaaaa
      361 ttcaaagaat tccaatgctt ttttcaagag caaatccgta tattctggat cttcttgggc
      421 tacttctatt tcccgctgaa ctttttccaa atcatctgta atcactccat ctactcctaa
      481 gtgaagagat ttgctgatag cttctgaatc attgacagtc cagacataaa gtttctgatc
      541 cgttgtccat agtttgctta caaaatattc atccaaggtt gagtactcca tagtatatcc
      601 tgtcgctctt gttttaggaa agacagaatt gtagggcatg atgaaataaa ctggcagttc
      661 ggcatcatac tgtcttactt tttcgacaac atggtagtct aaagactgga tttgatgtcc
      721 ataaatcttg agctttgcag cataacgggc taaaaagcgg ttcatcatgt ctggactatc
      781 ttttttactg gttttaattt caattagtaa tttttgacca agttcgttgg ctcgactgag
      841 ataatcttca aagcttgaaa ttttagtctg gtagccattt tcaaaaatat caatcccttt
      901 aagctcctcc aagtttaagt cttgaggact tttattgata cctgctagat ttttcaagtt
      961 agcatcatgc atcatgacaa actgcccatc ttttgtttcc tgcacgtccg tctccaccaa
     1021 gtctggtttg agttgtgctg tagtttccaa ggactctact gtattttgaa tcccatttgc
     1081 attggaaacc cctcggtgag aaataagttg aggtagatga accatgggag cctccagata
     1141 aatataacct tctaaggcaa agaaaagact ggcacaagtc atgacacccc atcgcacgat
     1201 gtgatctttt tctctcctag gaagcatatc cagctccttt cctgtcaaaa atgaaacaaa
     1261 tttaaccaaa aaataagtca gagccatata atagagattt ttaatcacga caaaattcaa
     1321 aataccaaga atcagagact ctctctgagt gatatcatct accaaagttt gagccaataa
     1381 taaagggatc aaaggaagat aaaataataa atgtgctttg agcaagatgt aaaataaatt
     1441 ccaagcataa aaagtaactc tcttcttggt tttctccaag ctaaacatca ctgcttctcg
     1501 aacagtcagc tgatcatata caatcttcgg aagggcaaac atcaatctga cagagacata
     1561 gagaaagata agagatagaa gtaggatgct cagccaccac atccaatatc tatcttctaa
     1621 ataagcttgg ataaactctg gaatgacgat tttattaaga taataaatct tcagcatttt
     1681 ccgtataaaa ggaaacagca tagctatata gaaaaagata aacaaggctt tagcgcaagt
     1741 tagctttttc ataaatccaa aactttcatg gaaaaccttg cggatatact caattagcct
     1801 tcgcttttca ttatagagga gatgacgagc accaataaag aggagtccta tttgaaaata
     1861 agcaaccaga aggttaatta caatcaaggc taaaaaagct agactaatca atggagaatg
     1921 agtaaggatg gctaagacat tgttatagga aataaaaaga taacctgtct gatctaataa
     1981 gaagctagcc aaccatgaat tgaatggtac ccacaaatac tccactatca taaaaatcaa
     2041 gaaaaataga aagaggattt tatcaagatt gaggtaaatc tgtttaagac ccaatttttt
     2101 aggtttttca ggtttcatag gcactcctag tcaaataatt gagacaagtc caagccacca
     2161 aaaggattgt ttgataagct actttctgtc tctaacaatt ccctagcttg atccgactct
     2221 aagaaggatt cgtaaacacg cgccgtcatc cgagcatcct ctaaactatt atgagactga
     2281 ccttgaaatc caagaaatga ggcaacagtt tgcaatttga gattggcaat accatgtaaa
     2341 tctgaactcc gacgttcaaa agcttcatca tacaaatcca ccttgtactg ttggctatag
     2401 tctaaaccat gctctgctaa aataggtaaa tcacttttag cagcattgta gcctatcatc
     2461 agcaaagaac ccacaaactc ttggaattct tctaagactt tctcaactgg aggagcatct
     2521 tttaaggtct cagctgtaat cccggtcaaa ccattgataa agctttttag agggacgctg
     2581 gtatgaacat aggaatcata ggcatcgatt tcccgaccat ctctaaaacg cactgccgat
     2641 acttgaatca agtgtgtttg tccttcgtgc tgattaaatt ctaagtcaaa agcaatgtaa
     2701 tcttctaatc gttccattct gtacctctcc tctactgtct ctgttctaat caactatact
     2761 attcacaaac aaaagaagcc atcaggttag catttaacct aaacagctcc ttgattatcc
     2821 tccaaataaa cgagcaaaaa agcctttttt agtggattgg acttcttctt ttgcttggtc
     2881 cagctctagc ttaagatttt cttgatcctt catggcttga agggtcaatt gttgttgctg
     2941 atctaattgt ttgtctttct cagcaatctg acggtctttg atacgcatct gctcgtcttt
     3001 ttctgataac tgacgatcct tggcttttaa ttgttcataa agacgaagaa tttctgcatt
     3061 cttctcatcc actagaatct ccatcagttc acgttgtttg acatcttcac tgacaggttc
     3121 atcttcaaaa atcgtttttt tatagatttc ttctagctta atcaagccac ttctggtaac
     3181 aactgttacc cctttgtcat ttttatctgt gtcttcttct ggtaattctt tgacacggtt
     3241 attgattgct tggcgagata atcctaagac ctctgcaatc tcactgacgg tcatttcaat
     3301 actcataata tcctctgaaa cgttttctag cttttcttta cttaaatctt atcataagct
     3361 agaaaaactg tcaaatttcc gcttaatcta aagccttcaa aaaggccaac aagacttggg
     3421 cagagcgacg tccagcttcg ataataaact catcaaaaaa gatgtttgct tcatggttgg
     3481 cattgtcact catagctctg atgactaaga ctgggagatt gagggcatgc gctgcttgag
     3541 caatagctgc cccctccatc tccacggcta aaacttctgg gaaatgggac ttaatcgctt
     3601 ctatcttgtc atttcctgca acaaaactat ctcctgtagc aatcaaacca agatgccagt
     3661 tttggtccaa ttgagataaa ctctcttgga tttgagcaac aaaggttttg tctgattcga
     3721 aataaagcgg ttgttgcgcc atttgtccat aagcatagcc aaaagctgtg acatccacgt
     3781 catgataggc taatttgtca gcaatcacga catccccaac agcgatacct tctgctactg
     3841 ccccagctga acccgtatta ataagggcat ccacctggaa atgatcagcc aaaatcgcca
     3901 cactcatagc agacatgacc ttaccaattc cactttctac aagaacgact tcatgagaag
     3961 caatggttcc tgtatgatag gtattcccca aaacaacttg ctcctgggca ttgtctaaat
     4021 gctggaccag atgagccagt tcttctggca tagcagcaat aattcctatt ttcatttcaa
     4081 ttccttttct attacaaaag tttcattgct aaaacaagca aaatcaagag aaagatgacc
     4141 gcgaataaga ttttattcaa cttagaattg aagacatttc tcttggtatt ttcaatgcga
     4201 cggcttttat gaatagatgg ttcgacctga atcttcaagg tttcctggct aaaaccatga
     4261 tccttaggat tggcataacc aaaacgggaa gaagaggttg gtaaaatctt agtttcctca
     4321 ttatcatcca gcaaaggagg acctgaaatt ttttcgcctc tattagctct ttcaatcatt
     4381 tcatccgtta ataaagattt acccatactg acctcctcta ttttttctgc aactcccaat
     4441 actgaacagc cataattgtc ttggcatcac agatatgacc tgattggatt aattctttcg
     4501 cttcttctaa gctcacttca aggacttcca aggtttcatc ctcatcctgc ggacgcggat
     4561 tttccacttt tgtcaaatcg cttgctaaat atagttttaa cttctcatta caaaagccaa
     4621 tagctgaata aaaatcgtac aagagttcta atttccctgt ataggctgtt tcttcctcta
     4681 attcacgaag ggcagctgcc acaggggctg tgttttctcc tacctccaat tttccggctg
     4741 gaatttcgta agagacagcc tcgatagctt tgcggtactg cttgaccaag ataagttttt
     4801 gttcatccgt tactgctaaa acacagacag ccccattgtg gaaaatcaaa tcccgttggg
     4861 cagttccctt gccttctggt aattcaacct gatcttggac cagtttaaat attggtcctt
     4921 gatagatttc ttttcggcta agcgtttttt cttcaaactc catgataggc tcctactggt
     4981 tcctaggatg atgaggaaga cgtgttgcat attcgtcttt attgatctga cgaccgcgac
     5041 caatagcaat agcatctgct ggcacgtctt tagtaatagt tgaaccagca ccaacgaggg
     5101 aattgtcacc aagttctact ggtgcaataa tggttgaatt tgaaccaaca aagacattgt
     5161 ctccaatgac tgtcttgtat ttgtttttgc cgtcatagtt gactgtaata gttccagcac
     5221 cgaaattaac gttgcttccc acttcacagt ttccgatata agtcaaatga ccagccttgg
     5281 tattctcacc gattgaagat cctttcacct caacaaagtt accaatatga acttgggcac
     5341 ccagacttga atttggacga atgtgagcat aaggaccgac tgtcacaccg tctgcaacac
     5401 tactttcctc aatcatagaa ttggtaatga ccgctcctgc tccgatagtg ctgtccacta
     5461 cataagtacc gtttgtcaaa acagtctcag caccaatttt cgtttgccct ttcaaggtaa
     5521 cattggcttc gatttgaact tccggagcaa tctcaacatc aatatcgata taagttgctt
     5581 ctggattgac aaagctaaca ccattgacca tgtgtttatg attgatgcga caacgcataa
     5641 ctgactcagc tgtcgcaagc gccacacggt catttacccc aagactttca tcaaaatctt
     5701 tcaaagtata agcgccaact ttttcaccag tttcacggaa aataccaatg acgtctgtaa
     5761 tatagtattc gccttgagcg ttattggtat tgatattttt caaagcctca aacaaacgct
     5821 cgttgtcaaa gacgtatgtt ccagtgttga tttccttgat ttgcttttca aaatctgtag
     5881 catccttctg ctcaacaata cgaagaacct cagcattgtc attacgaaca attcgtccat
     5941 agccaaaagg attatccgtt tcagcagtca agatagtggc cacattttta tgattgatat
     6001 ggaaatcaat caagtttttc aagctttcac cagtgattaa aggagtatct cctgcaatga
     6061 ccaaggtgtg tcctgacaaa ccttctaaga taggctctgt catcataact gcatgaccag
     6121 ttcccaactg ttcagattga gtcacaaatt ctgtctgtcc agccaagacc tcctcaacca
     6181 attctgcctt gtgtcctaca actgttactg tcttttcagg ttggatagct cccacactac
     6241 ggaaaacatg ttccaacata gaaatacccg caaccttgtg caaaactttt ggcaaatcag
     6301 atttcatgcg agtcccttta cccgctgcta aaataatggc aaaatttgac ataatcttct
     6361 cttttctgta gaaattccct tttattatac catatttcaa atcattccgc actcttgaat
     6421 gaaaaaatgc tctaaagtct cttccttaac ccattttttt gatttttagg gtagaattat
     6481 aagatatgag aaaacaaatt catccactta ttttatttag ttttttgggg attatgatgt
     6541 tcattttaat catcaatcgc ccacttaatg acaaccaatc gtttaaaaca aaatccaata
     6601 tagcacagat tgaagcacag gctttgaaac acttagacaa accgattatt gacctctctg
     6661 gctggcagcg tcctgaggaa atcaactacg atgccctctc acaaaatatt tcaggtgcta
     6721 ttgttcgtgt tcacagtggt gctcaaacga caaaagaaaa tgatgcttca tttatcaatg
     6781 gaatagacaa ggcctataag agtcatatca ctgaacttca aaagcggaat gtcccagttg
     6841 ctgtctacgc ttatgtagct ggaaaaagtg tccaagaaat ggaaaaggct gccgaagttt
     6901 tctacaatgc tgcctctcct tacagcccta gttactattg gcttgacgtg gaagacaaaa
     6961 ccatgtctaa tatgaacgaa ggtgtcgaaa actttcgagc aaaactagca tcactaggtg
     7021 ctaaaaacat cggcatctac gttggtgtct acttcatgga agaacacagt attgatacag
     7081 gcaagtttac ctctatttgg attccgtcct acggctcaga ctcaggattt ttggagagca
     7141 gtcctaaaac tgatttagat tatgatattc accaatacac atctaaagga aaaattgccg
     7201 gctttgacca cgatttagat atcaacgtta tctctccctt aaaaaataaa gaagaaacct
     7261 ttcgaaaact ttttttaaaa ccttaaaagc atttgtttat catttgcttt ttctttttgt
     7321 gtctgattgt gatacaatat agtaaggatt ttttgaaata gaaatagttg gaggaaatat
     7381 atgctctcat ggttagcacg cgttattaaa ggaattgtga ttgctcttgg atttatccta
     7441 ccgggaattt ccggaggggt tctagcagca atcttaggaa tctatgaacg aatgattggc
     7501 tttctggctc atccctttaa agaccttaaa gaaaatgttt tgtactttat tccagttgcc
     7561 atcggtatgc ttctgggaat cggcttattt tcctacccga ttgaatacct gcttgaaaat
     7621 tatcaggtct ttgtattatg gagctttgcg ggagctatta tcggtacagt tcctagcctc
     7681 ctcaaagaat caactcgaga atctgaccga gacaagattg atttagcttg gttatggaca
     7741 acctttatca tttctggatt aggactctat tccttaaatt ttgtcgttgg aaccttaagc
     7801 gccagctttc ttaacttcgt cctagcaggc gcactattgg cccttggcgt cttggttcct
     7861 ggcctcagcc catcgaattt acttttgatt ttgggactct atgctcctat gttgactggt
     7921 tttaaaactt ttgatctctt gggaaccttc tttccgattg gaattggtgc aggtgcaact
     7981 ctcatcgttt tttcaaaatt gatggattat gccttaaaca actaccactc acgcgtctat
     8041 catttcatca tcggtatcgt cctatcaagt acccttttga tcttaattcc aaatacagga
     8101 aacgctgaaa gtatccaata cacaggactt tcacttgtcg gttatgtcat catcgccttc
     8161 ttctttgcgc tgggaatctg gcttggtatt tggatgagtc aattggagga taaatataaa
     8221 taatggcaaa aaaagttaaa atcaaaaaaa cattggtgga acaaatccta tctaaagcag
     8281 ctatccctca tcaggggatt caaatcaatg ccctagaagg agagcttcct caaggttatg
     8341 aacgagatca gattttcaaa accttggcgc ttttgggaga caagaccgga ccgattatcg
     8401 gaattgtccc tatcactcag cacttgtctg aaaagaaact agctaaaatt tctggcaata
     8461 aaaaagtgag catgattcca caaaaggact tagaaaaaac aactggttac attcatggag
     8521 ccaataatcc tgtcggaatt cgtcagaaac acaattatcc catttttatc gataaaattg
     8581 ctctagattt ggatcgaatg attgtctctg caggcgaagt cggacacagc attatcgtcg
     8641 cgccacaaga cttggctagc tttgtaaagg cagactttgt agatattttg gaggacatca
     8701 agtaatgaaa ctctactttg tccgccacgg tcgtaccctc tggaaccaag aaggtcgttt
     8761 tcaaggtgct agcggtgatt ctcctcttct tcctgaatcc attgaaaccc taaaacgact
     8821 tggccagtat ctcaaggaaa ttccttttga tcagatttat tcaagtgatt tacctcgagc
     8881 ggtcaaatct gctgagatta tccaaagtca actccatacc ccctgttctt tagaaatcgt
     8941 tcctaatctc cgtgaatggc aacttgggaa gttagaaggt ttgaaaattg caaccttgga
     9001 agctatttac ccgcaacaaa tccaggcttt tcgttcaaat cttgctcaat ttgacactcg
     9061 aatgttcgga gccgaatccc tctatagtac aactcagcgg accatccaat ttatcaaatc
     9121 attaaaagat agtccagctg atcgtattct aattgtcgga cacggcgcca atcttactgc
     9181 cagtcttcgt actctcctag gctataaaga accacttctt cgtaaagatg gcggtctagc
     9241 aaatgccagc ctgaccatta tagaaaccca tgattttgaa acattcactc tcaatacttg
     9301 gaatgatact tcttatcaat cataattata gcctagcctt ctgaactaga accataggag
     9361 atatagtcag ttgaaacaaa aataagacaa aagaaccttg taaaaaggta ttgcaacttg
     9421 ccaatacctt tttgatatga acacgtgtct tctcaacagg attgtagagc aaaatgaaat
     9481 aagaactgaa taatatgatt tgagaattta aatcaattta taagaatgtt ttagaagcag
     9541 ttatgtacta ttttagattc acttttctat actaagatga gtagggagga aaaggtaaaa
     9601 gtttatgccc aaattcttca cataagaact ctagcttacc cattctatgg aatcttgcat
     9661 tatccattaa aacttccaga ctcataccct tctaaaatct attcaaacca cgtcagcttc
     9721 acattatata tgttggtgac ctcacaagtt ttatctacaa cctcaaagct gttctttgag
     9781 cagcctacag ctagcttcct agtttaatct ttgcttttca ctgagtatca agttaaaaaa
     9841 atgaggctgg tcaaaaagtc tttaaaataa aaaacgcata ttatcaggtg ttaaatgaac
     9901 tgcaccccaa aagttagaca gaaaaaatct aacttttggg gtgtttttat tatgaaatta
     9961 acttatgatg ataaagttca gatctatgaa cttagaaaac aaggatatag cttagagaag
    10021 ctttcaaata aatttgagat aaacaattct aatattaggt acatgattaa attgattgat
    10081 cgttaatgtt ggaacaggca ttcaaagaga agcactacga gaatacgatt ctccatagtg
    10141 accaaggctg gcaatatcaa cacgattctt atcatcggtt cctagagagt aagggaattc
    10201 aagcatctat gtcacgcaag ggaaacagcc aagacaacgg tatgatggaa tctttctttg
    10261 gcattttaaa atccgaaatg ttttatggct atgagaaaac atttaaatca cttaatcaat
    10321 tggaacaagc cattatagac tata
//
LOCUS       DBEJKC010000066        10297 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.066, whole genome shotgun sequence.
ACCESSION   DBEJKC010000066 DBEJKC010000000
VERSION     DBEJKC010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.066"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            87..1262
                     /gene="mutY"
                     /locus_tag="ACL3G6_001810"
     CDS             87..1262
                     /gene="mutY"
                     /locus_tag="ACL3G6_001810"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HGR0546288.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1317..2021
                     /gene="yycF"
                     /locus_tag="ACL3G6_001811"
     CDS             1317..2021
                     /gene="yycF"
                     /locus_tag="ACL3G6_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HGR0546289.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2014..3363
                     /gene="vicK"
                     /locus_tag="ACL3G6_001812"
     CDS             2014..3363
                     /gene="vicK"
                     /locus_tag="ACL3G6_001812"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HGR0546290.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3365..4174
                     /locus_tag="ACL3G6_001813"
     CDS             3365..4174
                     /locus_tag="ACL3G6_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGR0546291.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4265..4507
                     /gene="relB"
                     /locus_tag="ACL3G6_001814"
     CDS             4265..4507
                     /gene="relB"
                     /locus_tag="ACL3G6_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HGR0546292.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4509..4763
                     /locus_tag="ACL3G6_001815"
     CDS             4509..4763
                     /locus_tag="ACL3G6_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGR0546293.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4810..5553
                     /locus_tag="ACL3G6_001816"
                     /pseudo
     CDS             4810..5553
                     /locus_tag="ACL3G6_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005267 - potassium channel activity
                     [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
     gene            complement(5854..6840)
                     /locus_tag="ACL3G6_001817"
     CDS             complement(5854..6840)
                     /locus_tag="ACL3G6_001817"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HGR0546294.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            7034..9502
                     /gene="gyrA"
                     /locus_tag="ACL3G6_001818"
     CDS             7034..9502
                     /gene="gyrA"
                     /locus_tag="ACL3G6_001818"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HGR0546295.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLTEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            9502..10245
                     /gene="srtA"
                     /locus_tag="ACL3G6_001819"
     CDS             9502..10245
                     /gene="srtA"
                     /locus_tag="ACL3G6_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HGR0546296.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         3197 a         1750 c         2293 g         3057 t
ORIGIN      
        1 tagatagaaa agttatatac tatctattga aaatattata aatcagatac aaagacaggt
       61 gaaaccttct gtgttatact agagatatgt tagatttgaa agaatacggt atcgtcatgt
      121 ggccggagga gaaagtcatt tctttccgtg agaaacttct cgcttggtat gatgaaaaca
      181 aaagagattt gccttggagg agaagtaaaa atccttatca catctgggta tctgaaatca
      241 tgcttcagca gaccagggtg gatacagtta tcccttacta cgaaagattc ctggactggt
      301 ttccaactgt cgaaagtctg gcaactgcgc ctgaggagag tttactgaaa gcttgggagg
      361 gcttgggcta ttattctcga gttcgcaata tgcaggctgc agcccagcag attatgactg
      421 actttggtgg ccaatttcca aatacctatg aaggaatttc cagcttgaaa gggattggac
      481 cttacacagc aggagccatt tccagtattg cttttaactt gcctgagcca gctgtagatg
      541 gtaatgtcat gcgggtcttg gcgcgtctgt ttgaagtcaa ccacgatatt gggattccaa
      601 gtaatcgaaa aatttttcag gcaatgatgg agatcttgat taatccggat cgtccgggtg
      661 attttaatca agccttgatg gacttagggt ctgatattga gtctcctgta aatcccagac
      721 ctgaagaaag cccagtcaag gactttagtg cggcatatca gaatggaacc atggaccgtt
      781 atccaattaa atctcctaag aaaaagccgg ttcctattta tcttaaagcc ttagttgtga
      841 aaaattctca aggacaattt ttacttgaaa aaaatgaaag cgaaaagctc ttggcaggtt
      901 tttggcattt cccctttata gaagttgata acttttcgca agaagagcag tttgacctct
      961 ttcatcaggt tgcggaagaa agtgtgaact ttggccccag tccagaagag agtttccagc
     1021 aggactatga cctagatgtt gattggcttg atgtttgttt tgatacagtc cagcatgttt
     1081 ttagtcatcg aaaatggcat gtacagattg tagcaggtca ggtgagtgac ttccatgatt
     1141 tttcagatag ggaagttcgt tggctttcac cagaagaatt caagaattac ccacttgcca
     1201 aaccccaaca aaaaatctgg caggcttatg cacaagccaa cttagacagt agccaagact
     1261 agctattgtg tcttctgact attttttggt ataatagtag agaaaaaggt gaacatatga
     1321 aaaaaatact aattgtagat gatgagaaac caatctcgga tattatcaag tttaatatga
     1381 ccaaggaagg ttacgaagtt gtaactgctt ttaatggtcg tgaagcgcta gagcaatttg
     1441 aagcagagca accagatatt attattctgg atttgatgct tccagaaatt gatggtttag
     1501 aagttgctaa gaccattcgt aagacaagca gtgtgcccat tcttatgctt tcagccaaag
     1561 atagtgaatt tgataaggtt atcggtttgg aacttggggc agatgactat gtaacgaaac
     1621 ccttctccaa tcgtgagttg caggcgcgtg ttaaagctct tctgcgtcgt tctcaaccta
     1681 tgccagtaga tggtcaggaa gcagatagta aacctcaacc tatccaaatt ggggatttag
     1741 aaattgttcc agacgcctac gtggctaaaa aatatggcga agaactagac ttaacccatc
     1801 gtgaatttga gcttttgtat catttagcat cgcatacagg tcaagtcatc acgcgcgaac
     1861 acttgcttga gactgtctgg ggttatgact attttggtga tgtccgtaca gttgatgtga
     1921 ctgtacgacg tctgcgtgag aagattgaag atacgcccag ccgaccagag tatatcttga
     1981 cgcgccgtgg agtagggtat tacatgagaa ataatgcttg atttactgaa acaaaccatt
     2041 tttaccagag attttatctt tatcctgatt ttgttaggtt tcatccttgt tgtgaccctc
     2101 ttattactgg aaaatagacg tgataatatt cagttgaagc aaatcaatca aaaggttaaa
     2161 gatttgattg caggagatta ttccaaggtt cttgatatgc aaggtgggtc tgaaatcacc
     2221 aatattacca ataatttgaa tgacttgtcg gaggttattc gtctcactca ggaaaatcta
     2281 gaacaagaga gtaagaggct aaatagtatt ctgttttata tgacagatgg ggttcttgcg
     2341 accaaccgtc ggggtcagat tatcatgatt aacgatacag ccaagaagca actggggttg
     2401 gttaaggaag atgttctgaa tagaagcatt ttggaattgc tcaagataga agaaaactat
     2461 gaattgcgtg atttgattac ccaaagtcca gaattgttgc tagattccca agatatcaat
     2521 ggcgaatatt tgaaccttcg agttcgcttt gccttgatac gtcgagagtc tggctttatt
     2581 tcaggtttgg tggctgtttt gcatgatacg acggagcagg agaaggaaga acgcgaacga
     2641 agactctttg tttccaatgt tagccatgag ttacggactc ctctgactag cgtaaaatcc
     2701 tatcttgaag ccttggatga gggggctttg tgtgaaactg tagcaccaga ctttatcaag
     2761 gtttctcttg atgagaccaa ccgtatgatg cgcatggtga cggatctcct ccatctttca
     2821 cgtattgata atgctaccag tcacctagat gtggaactga ttaacttcac tgcttttatt
     2881 acctttatcc tcaatcgttt tgacaagatg aaaggacagg aaaaggagaa aaaatatgag
     2941 ttggtgagag attatcccat caattctatc tggatggaaa ttgatacaga taagatgacg
     3001 caggttgtcg acaatatttt aaataatgct attaagtatt cgccagatgg gggtaaaatc
     3061 actgtcagaa tgaagacaac tgaagaccag atgattttat ccatttctga ccacggtttg
     3121 gggattccta agcaggattt accacgtatc tttgaccgtt tctatcgtgt ggatcgtgct
     3181 agaagtcgtg cgcaaggtgg tacaggtcta ggactgtcta tcgctaaaga aattatcaaa
     3241 caacataagg gctttatttg ggccaagagt gaatacggca agggttcaac ctttaccatt
     3301 gtgctccctt atgataagga tgcagtgaaa gaagaagtat gggaggatga agtagaagac
     3361 tagaatgagt gaaataggct ttaaatacag tattttagcg tcgggttcca gtggaaattc
     3421 tttttatctg gaaacctcaa aaaagaagct tttagtagat gcaggcttgt ctggcaagaa
     3481 aattaccagt ctgctagctg aaattaaccg taagccagaa gacctggatg ccatcttgat
     3541 tacccatgag cattcagatc atatccatgg agtaggcgtt ttggctcgca agtatggtat
     3601 ggatctttat gccaatgaaa agacctggca agctatggaa aatagtaaat atcttggcaa
     3661 ggtggattct tcgcaaaagc atatttttga aatgggtaaa accaaaacct ttggagatat
     3721 cgacatcgag agttttggtg taagccatga tgcagtcgca ccgcagttct atcgctttat
     3781 gaaggatgat aagagttttg tccttttgac agatacaggt tatgtcagtg accgtatggc
     3841 gggcattgtc gaaaatgcgg atggctatct tatcgaggcc aaccatgatg tagagatttt
     3901 gcgatcaggt tcttacgctt ggcgactcaa acaacgaatc ctatctgacc ttggtcacct
     3961 ttctaacgag gacggtgctg aagctatgat tcggacgcta ggaaatcgta ctaagaagat
     4021 ttaccttggg catttatcta aggaaaataa tatcaaggaa ctggctcata tgaccatggt
     4081 caatcagctg gctcaagctg atctgggagt cggagtagac tttaaggttt atgatacctc
     4141 accagatacc gcaacaccat tgacagagat atagaaagaa cgctgagaag gtgttctttt
     4201 tatattgact gaacacctaa aaagtaatac aatggtgtta ccattaaaaa agggagcaca
     4261 aaagatgact actattacat taaaagtttc tgaagctgat aaaacattta tgaaagcaat
     4321 ggctaagttt gaaggagttt ccctttcgga acttattcgc accaaaactc ttgaagccct
     4381 agaagatgaa tacgatgctc gtgtggcaga tttagcctat caagagtatt tagaagactt
     4441 ggaaaaagga gttgaaccca ttacttggga agaaatgatg catgatttag gcttgaagga
     4501 tgaataattt gtataaatta gttccaacaa gacgttttat caagcaattg aaaaaattgg
     4561 accgttatac gcagaagcta attacaaact atttacaaac caatgttttg gaaggtccaa
     4621 gacgacacgg aaaggctttg gttggtaatc gcgttggtca atggcgctat agaattggta
     4681 attatcgagt tatcgtacaa attgtagatg atgaattagt cgttgctact ctagaagttg
     4741 gtcatcggag agatatttat tgaattaaag ctgagtaata acaatataga aagtaaggag
     4801 agtaaaaatt tgaagaaaaa atggttattt gcagattatt atgatacaac aattatttta
     4861 cttgctttaa tctctgttat tctggtatta cttggatttg ctgagatgac tgatttggac
     4921 aatccgcctt atagtattat tgatttagta atctggggtg tttttgtaat tgattatagt
     4981 tggcgctttt ttattactaa aagaaaatgg cgctttattc ttgaaaatat ttttgattta
     5041 ttgaccattc tccctttaaa tgctattttt acagtgtttc gattaggacg tatcttccgc
     5101 ttagcaaggc tgacaaaatt actgaaactg actcgtttac ttagaataat tggacttaca
     5161 ggtaaactag aaagaaaaat tagtagattc ttacgaacaa atggattgat ttatatcttg
     5221 tatgttaata tctttattgt tctagtaggg agttcgattt tatccgttgt tgaagaaaaa
     5281 tccttctcag atagtctttg gtgggctctt gtgacagtaa ctactgttgg ttatggtgat
     5341 attgttccag tttccctttt tgggaaatgg ctagcagttt tactgatgct tgtcggtatt
     5401 ggaacaatag ggatgctaac aagtgctttg acgaactttt ttgtaaagga taatccagat
     5461 gaacagataa aacttgataa actcaaagac gaattatcga gctaaagaat attaatagag
     5521 aaacaatctg aaaaaatcga agaactacat tgaatgataa aagacttagt tgaaaaaata
     5581 tcataaaggt gagacaaaat aaaacttgat tcgaggagaa atcaagtaag ttttgacaca
     5641 atagaacgca tattatcagg tataaaaact tgatactatg cgttttatag agaaataaaa
     5701 taaaatctga acaaatcaat taggaattta aagcatttta taacaacgtt ttagagtaat
     5761 ggggtgctat ttcaacttca acctactata atacagaaaa aaatacagaa aaaaacaact
     5821 ccctgatgat tcaaggagtt gtctatagtt aaattagttt ttagaagctt cttggaattc
     5881 tggatttttc catgcttcgt caataatagc ttgcaattct ttagcagatg cttgcatttt
     5941 ttgagtttct gcatcgttca atggaatgtt tactggacga acgataccat gtgcaccaac
     6001 aacagctggt tgaccgataa agacattctc aactccgtat tgaccttctt ggaatactga
     6061 aagtggaagt actgcgtttt catcgtcaag gattgcttta gtgatacgag caagggctac
     6121 tgcgataccg tagtatgttg cacctttttt gttgatgatt gtgtaggctg catcacgaac
     6181 accttcgaac aattcaatca attcagcttc ttgaacattt tgagtgtctt taaggaattc
     6241 ttcaagattt acaccagcga tgttagcgtg tgaccaaaca gcgaactcag agtcaccgtg
     6301 ttcacccatg atgtaggcgt gcactgaacg agcatccaca tccaattttt cagcaagtgc
     6361 ttgacggaaa cgagctgagt caagtgaagt acctgaaccg ataacgcgtt ctttagggaa
     6421 accagagaat ttccaagttg agtaagtcaa aacgtcaact gggttagcag caacaaggaa
     6481 gatacctttg aaaccagatt caacaacttg agttacgatt gatttgttga tagcaaggtt
     6541 tttacctaca aggtcaagac gagtttcacc tggtttttga ggtgcacctg cagtgatcac
     6601 aacaaggtca gcgtctgcac agtcagagta ttgagctgca tagatttttt taggtgaagt
     6661 gaaggcaagg gcgtgactaa ggtcaagcgc atcaccaaca gctttttcat gcaattgtgg
     6721 aatttcgata attccaagct cttgtgcaat tccttggtta acaagtgcaa aagcgtaaga
     6781 tgaacctaca gcaccatcac cgacaaggat aacttttttg tgttgtttag ttgaagtcat
     6841 tgttttaaac atctccttaa ttttattagg ggattttccc tagacaactt cattctatca
     6901 cttttaaaaa actttgtcac gaatatgcct tatagttctc gatgtaaacg ttttagtggt
     6961 ttagaggctg aaatagatgg gaatttatgg tataatgttg ttacttacta attgtgaaat
     7021 gaggcattta ttaatgcagg ataaaaattt agtgaatgtc aatctgacaa aggagatgaa
     7081 ggcaagtttt atcgactacg ccatgagtgt tatcgtagcg cgagctcttc ctgatgttcg
     7141 agatggctta aaacctgttc accgtcgcat tctctacgga atgaatgaat tgggtgtgac
     7201 cccagacaaa ccccataaaa aatctgctcg tattacaggg gatgtcatgg gtaaatatca
     7261 cccacacggg gattcctcta tttatgaagc catggtccgt atggctcaat ggtggagcta
     7321 ccgttacatg cttgtagatg gtcatgggaa ttttggttcc atggatggag atagtgctgc
     7381 cgctcaacgt tataccgagg cacgtatgag caagattgct ctggaaatgc ttcgtgatat
     7441 caacaaaaat acagttgatt tcgttgataa ctatgatgcc aatgaacggg aacccttggt
     7501 cttgccagcg cgttttccaa accttttggt taatggagca actggtatcg cggttgggat
     7561 ggcaaccaat attccacctc ataatctggg tgaaaccatt gatgcagtga agttggtcat
     7621 ggataatcct gaagtgacta ccaaggactt gatggaagtc ttgcctggac cagattttcc
     7681 aactggtgct cttgtcatgg ggaaatcagg tatccataag gcttatgaaa caggtaaagg
     7741 ttcgattgtc ctacgttctc gtacagagat tgaaacgact aagactggtc gtgagcgtat
     7801 cgttgtaaca gaatttcctt acatggtcaa taaaaccaag gtgcatgagc atattgttcg
     7861 cttggttcag gaaaaacgca ttgagggtat cacagcagta cgtgatgagt caaaccgtga
     7921 aggtgttcga tttgttattg aagtcaagcg cgacgcctca gccaatgtta ttctcaataa
     7981 cctcttcaaa atgacccaaa tgcaaaccaa ttttggattc aatatgctcg ctatccaaaa
     8041 tggtataccg aaaattttgt ctcttcgtca gattttggat gcttatattg agcaccaaaa
     8101 agaagtggtt gttcgtcgta cacgttttga taaggaaaaa gcggaagcgc gcgctcatat
     8161 cttagaaggt ctcttgattg cgctagacca tatcgacgaa gtgattcgta tcatccgtgc
     8221 tagtgaaacg gatgcggaag ctcaagctga gttgatgagc aagtttaagc tttctgaacg
     8281 tcaaagtcaa gctatccttg atatgcgtct tcgtcgtttg acaggtttgg aacgcgataa
     8341 gattcaatct gagtatgatg acctcttggc tctgattgcg gatttagcag atattcttgc
     8401 taagcctgaa cgtgtttctc aaattatcaa agacgaattg gatgaagtta aacgtaaatt
     8461 ttctgataaa cgccgtacag agttgatggt tggacagatc ttgagtctcg aggatgagga
     8521 cttgattgaa gaatcggatg tcttgattac cctttctaac agaggctaca ttaagcgttt
     8581 ggatcaggac gagttcactg ctcaaaaacg tgggggtcgt ggtgtccaag gaacgggagt
     8641 gaaagatgat gactttgttc gtgagttagt gtcaactagc acccatgatc atctgctctt
     8701 cttcacaaac aagggacgtg tctatcgtct taaaggttat gaaattcctg agtatggtcg
     8761 gactgccaaa gggctaccag tagtcaatct cttgaaattg gatgaagatg aaagtattca
     8821 gacggttatc aatgttgagt ctgatcgcag tgatgatgct tatctcttct ttacaacccg
     8881 tcacggtatt gtgaagagaa ctagtgttaa ggagtttgcc aatattcgtc aaaatggtct
     8941 caaagcgctg aatttaaagg atgaagatga gttaatcaat gtcttgttga cagaaggaga
     9001 tatggatatt atcattggta ccaagtttgg ttatgcagtt cgctttaatc aatcagccgt
     9061 tcgtggtatg agccgtatcg ccactggtgt gaaaggtgtt aaccttcgtg aaggagacac
     9121 agttgttggt gccagcttga ttactgatca agatgaggtt cttattatca cagaaaaagg
     9181 atatggtaag cgtacagtcg ctactgaata cccaacaaaa ggtcgtggtg gtaagggaat
     9241 gcagacagct aaaattaccg aaaaaaatgg cttgctggcc ggtcttatga ctgttcaagg
     9301 ggatgaggat ttgatgatta tcactgatac aggtgtcatg attcgaacca atcttgccaa
     9361 tatttcacaa acaggacgtg caactatggg agttaaagta atgcgcctgg atcaagatgc
     9421 tcagatagtg actttcacaa cggttgcggt ggcagaaaaa gaagaagttg ggacagaaaa
     9481 cgaaacagaa ggtgaagcat aatgtctcaa aaaaataata aaaagaaaaa caagcgaaaa
     9541 aatctgctga caaatatcct agcaggattt ctgatattac tgtcactggc tttgattttt
     9601 aatactcaaa ttcgaaatat tttcatagtc tggaatacca ataagtatca agttagccag
     9661 gtatcaaaag aaaaattaga agaaaatcag gatacagaag gcaattttga ctttgattct
     9721 gtcaaagcta tctcttcgga agctgttcta acttctcaat gggatgctca aaaattacca
     9781 gttattgggg gaattgcaat tcctgaattg gaaatgaatt tgccgatttt taaaggactt
     9841 gataatgtta atctcttcta cggagctggt acaatgaaac gcgagcaagt aatgggagaa
     9901 ggaaattata gtctagctag tcaccatatc tttggtgttg ataatgctaa taaaatgtta
     9961 ttttctcctt tagataatgc taaaaatggc atgaagattt atctaaccga taaaaataaa
    10021 gtttatactt atgaaatacg tgaagtcaaa cgtgtgacac cggatcgtgt tgatgaagtt
    10081 gatgatagag atggggtcaa tgaaatcaca ttagtaacct gtgaagacct tgctgctaca
    10141 gaacgtatta ttgtcaaagg tgatttgaaa gaaacaaaag attattcaca aacatctgat
    10201 gaaattctaa cagctttcaa tcaaccatat aaacaatttt attaatacaa atcagtgaaa
    10261 tcatggattt cactgatttt ttaagatttt cataaaa
//
LOCUS       DBEJKC010000067         9438 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.067, whole genome shotgun sequence.
ACCESSION   DBEJKC010000067 DBEJKC010000000
VERSION     DBEJKC010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.067"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(381..1577)
                     /gene="tuf"
                     /locus_tag="ACL3G6_001820"
     CDS             complement(381..1577)
                     /gene="tuf"
                     /locus_tag="ACL3G6_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGR0546297.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2499..3368)
                     /gene="gla"
                     /locus_tag="ACL3G6_001821"
     CDS             complement(2499..3368)
                     /gene="gla"
                     /locus_tag="ACL3G6_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaglyceroporin Gla"
                     /protein_id="HGR0546298.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3592..4212)
                     /locus_tag="ACL3G6_001822"
     CDS             complement(3592..4212)
                     /locus_tag="ACL3G6_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR0546299.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKAPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPIPQPNPEHPSVPTPNPELPNQETPIPEPTPEPGTPKTETPVNLDPEV
                     PTYETGKREGLSNTGTEANATLASAGIMTLLASLVLGFFKKKEDEK"
     gene            complement(4170..5276)
                     /locus_tag="ACL3G6_001823"
     CDS             complement(4170..5276)
                     /locus_tag="ACL3G6_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HGR0546300.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVDSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5387..5641)
                     /locus_tag="ACL3G6_001824"
     CDS             complement(5387..5641)
                     /locus_tag="ACL3G6_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546301.1"
                     /translation="MLNVDQDFMSISKSNKSDSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(5635..5877)
                     /locus_tag="ACL3G6_001825"
     CDS             complement(5635..5877)
                     /locus_tag="ACL3G6_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546302.1"
                     /translation="MYQNEDLYKKGLNVELAHQQIKGFFEAEFKNRINGVLNTKIKNS
                     TLNRVNKKTIHQSNKNSMINLKQKQRKMLKNKAILC"
     gene            complement(5999..6532)
                     /locus_tag="ACL3G6_001826"
     CDS             complement(5999..6532)
                     /locus_tag="ACL3G6_001826"
                     /inference="COORDINATES: protein motif:HMM:NF024751.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HGR0546303.1"
                     /translation="MTIFKEQESEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(6519..6845)
                     /locus_tag="ACL3G6_001827"
     CDS             complement(6519..6845)
                     /locus_tag="ACL3G6_001827"
                     /inference="COORDINATES: protein motif:HMM:NF013842.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HGR0546304.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDDL"
     gene            7079..8797
                     /locus_tag="ACL3G6_001828"
     CDS             7079..8797
                     /locus_tag="ACL3G6_001828"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HGR0546305.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKEIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            8908..9255
                     /locus_tag="ACL3G6_001829"
     CDS             8908..9255
                     /locus_tag="ACL3G6_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGR0546306.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
BASE COUNT         2716 a         1932 c         1769 g         3021 t
ORIGIN      
        1 actattgtat aatgcttttt gatttgagtc tagtattata ctcttcgaaa atctcttcaa
       61 accgcgtcag cttcgccttg tcgtatagat gttactgact tcgtcagttc tatctacaac
      121 ctaaaaacag tgttttgagc agtctgcagc taactttcta taacaaaatg aaataagaac
      181 aagacaaatc aatcaagaca atcaaatcga tttctaacaa tgttttagaa gtagatgtgt
      241 actattctag tttcaatata ttatagtttg ctctttgatt ttcattgagt attagttcaa
      301 tatctaaaaa aagaaccttg ccaagcaaga ttcttttagt gtctgactta aataattgtt
      361 cttctgggaa ctaaatcgaa ttaagcttcg atttctgtaa ccatacctga accaacagta
      421 cgtccaccct cacggataga gaatgtagta ccttgttcta cggcgattgg gtgaatcaac
      481 tcaacgtcga ttgtcacgtt atcaccaggc attaccattt cagtacctgc tggaagttcg
      541 attgaacctg taacgtcagt agtacggaag tagaattgtg gacggtagtt gttgaagaat
      601 ggagtgtgac gtccaccttc ttctttagta aggatgtaga cttcaccttt gaatttagtg
      661 tgtgggttga ttgaacctgg tttagcgata acttgtccac gttcgatttc atcacgttga
      721 acaccacgaa gaaggacacc tacgttatct ccagcaagac cttcgtcaag ttgtttacgg
      781 aacatttcaa caccagtaac aactgctttt tgagtttctt ctttgatacc aacgatttcg
      841 atttcgtcgt tgactttaac gataccacgg tcgatacgtc ctgaagcaac tgtaccacgt
      901 ccagtgattg agaatacgtc ctcgactgga agaagcaatg gtttgtcagt gtcacgttct
      961 ggttctggga tatactcatc aactgtgttc atcaattcca taacgatgtc ttcgtattta
     1021 gagtcacctt caagagcttt aagtgctgaa ccttggataa ctggaagatc gtcacctggg
     1081 aagtcgtatt ctgacaatag gtcacggatt tccatttcaa ccaattcaag caattcttcg
     1141 tcgtcaacca agtcaacttt gttcatgaag acgataaggt gtttaacacc aacctgacgt
     1201 gaaagaagga tgtgctcacg agtttgtggc attggtccgt cagttgaagc tactacaagg
     1261 atagctccgt ccatttgagc agcaccagtg atcatgtttt taacgtagtc cgcgtgtcct
     1321 ggagcgtcga tgtgagcgta gtgacgtttt tcagtttcgt actcaacgtg cgcagtgttg
     1381 atagtgatac cgcgttcgcg ttcttctgga gcagcatcga tagacgcata gtctttaggt
     1441 tggttaactg atgaaggcaa gcgacgtgcc aaaacagttg tgatagctgc agttagggta
     1501 gttttaccgt ggtcaacgtg tccgatagta ccaatgttaa cgtgtggttt actacgatcg
     1561 tatttttctt ttgccatttg agtaaaagcc tccaataaaa tatattttat agatagacag
     1621 taggcaatac agtctaactt tccttactat tttatcaaat ttcagctaaa ttgcaagtgt
     1681 tttacaacgt ttttgtgaat tattcttggt aaaaatttaa ctaattaata gaaagtacta
     1741 aatagactta tccttcaagg agttttcagc attatccatc cactcacttg ctgaaaatgt
     1801 aaacagtctc tggtttatat agtaaaatga aacaagaata gggcaaatcg atcaggacag
     1861 tcaaatcgat ttctaacaat gttttagaag tagatgtgta ctattctagt ttcaatctac
     1921 tatacaacct caaaactgtg ttttgaacaa cctgcggcta gcttcttagt ttgccctttg
     1981 attttcattg agtataaaat tgcagataaa acgataacaa tcataggact cagcagagtc
     2041 aatgtaggtc gaagaatagc ccccctaatc gcttatttta tagcaaaatg aaatagaaac
     2101 tgaacatttt gttgaggaag gtaaatcaat tcctcacaat gtttgagaaa gaagggggga
     2161 ctattccaac ttcaacccac tataaagcag acttacaaga tagggaaccc atctccgata
     2221 atattccgat aatatatagt agaatgaaaa ctgcacaatt tgattggaga attcaaacca
     2281 atttctaaca atgttttaga aacaagggtc tattatttca actgcaacct actatagccc
     2341 attgaagctg gaatagccca ctgagacttc taaaccactg ctggagagga gtttgtttag
     2401 agtttctttc atttccctaa aaaatcaaaa agagagaacc agtctgatcc tctcttactt
     2461 atagatggtg ctcactcaaa tgttaaagga gctatttctt agagataaag gaatttgaat
     2521 acagctactg ccgcaattgc tgctgcgata ggtgctacta ctggtaccca agaataccac
     2581 cattttgaat cgcctttatg ctcaccaaga actgattttg gaaggaaagc atgaaggaga
     2641 cgtggtccca agtcacgggc tgggttcaag gcaggtcctg taggtcctcc aagtgatgtt
     2701 accaaagcca taacgaggaa tccaagtgcc aagtgagcca cagaaagtcc tgaagcagtg
     2761 tgtggagcca cctgtgcttt aatagccaag tcagaaaaat caactgtttg tcctgcttct
     2821 attgcctttt gtttcatgaa ttgaagcact tcagcaccaa agaagttttt agtcaaacca
     2881 agagctgcaa agaacaaaac aaatgaacca acaaactcat taatcaaacc attgacagtt
     2941 gctgcatagc gactttcttt tgtaccatgg tcaatacttg aaatagttga gaaagttccc
     3001 aagatgttat ttgggttttc agttttcaag tagaatggac ggtatgttgc cacaactaag
     3061 gcttggccaa agatagcccc caagacttgc gcgataatgt aaggtaccac ttgtgcccaa
     3121 gggaaaagac cgctaactgc aagccctaga gtgaaagcag ggttgatgtg attcccagat
     3181 acgttaccaa acatcaaggc tgggatcata acccccatac cataaccaac agcgatgacg
     3241 atccagccac tttggtgacc tttcgtacct ttaagttcaa cgttggcaac tgcaccattc
     3301 ccaagaatga tcaaaatggc agttcccaaa aattcagtgg catacttcag tgcccatgtg
     3361 aaatccattt gctagattct ccttaaaatt ttttagatat tccttatttt atcaattttt
     3421 accctattta gcaactgatt tctggaaata tttttaaaaa aataggattc atagtttccc
     3481 agttcaacgg acttgtaagc gtttttattc ttcacgaaag acctcgttct caaaaccagg
     3541 aaaaaagccc acatctgtga gcttttcctg gttcctagat tctaaaatct attatttttc
     3601 atcttctttt ttcttgaaga atcctaatac tagactagct aacaaggtca tgataccagc
     3661 actagccaag gtagcattag cttctgtacc tgtgtttgac aatccctctc tcttacctgt
     3721 ctcataagtc ggaacttctg ggtctagatt cactggagtt tcagtttttg gagtacctgg
     3781 ttctggagtt ggctctggta ttggagtctc ttgatttggt agttctgggt ttggtgtcgg
     3841 aacacttgga tgctctggat ttggttgtgg gattggtttt tctggagttg gtttatctgg
     3901 tgttgataaa cggtcatacc ttaccgttat ttctttatca ctagagtctg acgtaacttc
     3961 ttgtgattca actgttggaa tatctggagc tttgtacttg tcaatcttac cagatacaac
     4021 ctcgtcccag tttcctgttg tccattcacc gtaggttaca actcccgtga ccttgttctc
     4081 agtttttgta cggcttaagg ttacaggttg aacaacatct tcttttacat tttggttcgt
     4141 aactttatca acgtaatgaa tgatacgcgt tatagtcttc gtctcagtag aggttgctgt
     4201 tttgggaacc actgtttcct caacattctc acggtagtaa tagtcaactg ttgcaccgtc
     4261 ttctggtacg catttgcagg agttgctacc aaggtgtatg ttgttttcct tgtgataact
     4321 cggtcttctt tgtcctcagt tgttgttttc ccttcaatag tttttgattc tgtggtatac
     4381 tcagaaccta tcgctaaatc agcttttata acagactctg ccaacttctc ttggctacct
     4441 tctttatagt aattggctgt tactgtagca gtggttggcg cttcgctttc tctataaact
     4501 aaggtcactg ttctaccttc gcttacaata ttcccagtta aacttgcaga atttgtatct
     4561 gcttctttaa aagtataata ttttccgtca gtagtagtca tgctactgag ttttttatct
     4621 gtgacattgt agctggtacc aatcagttgt tttttattgg taatgtaggt tccgtcactt
     4681 tctttttctc caattccagt atcatttttc aatgatagca aacgcccttg ttcatcaaca
     4741 tagcgaactt tcacattttc tgagattagt tctgccaatt ctgaggtttt tttctttttc
     4801 ttgatttctt cggttatttt ccctttctct tcttcgggaa tatttagttt tggaatgatt
     4861 ttttcaacaa cggttcgtga tggttccaca gtatcttgga tgactgaaaa gtcagctaga
     4921 attgggagat tatactgaac acggtgactt tgagtgttta ctcctactct ttcattattc
     4981 tctgaaaata cttgtacggt ataagaaaca acatcttttc ctaatagaac atccccagta
     5041 gagaaatagc cgccttttcc tagtttgcta tctccagagt ccacttcttt cctaatctta
     5101 tcagatagtt ttttaccagt cagtacattc gttcgcacaa tccctttgtc tacccctaca
     5161 aagtgggaga actttttgaa ctcttcagaa ccagatctag cccaaccatt attaagggca
     5221 tttgcttttg tatttgtatt ctctctcaaa ggtttggcga ttagaattat attcatcggc
     5281 acttagagtt gctgctatat ctgactcttg aataccaact tccttactac catttctagc
     5341 ggcagtatat gtgtatttat ctgtttctac ttctagctga ttatccttaa catgataggt
     5401 aattttctcc tggtataaga gtcttcagta gtttatatgc tctgtcatca tctttagctt
     5461 tagaagcagc tgagtttagc caagttgggg tattaggagt atctttatca gcctgtttca
     5521 agacattatt caagtcattt gctaacctat tggttgtcct cactgtgaaa gttttcttcc
     5581 agtctgaatc acttttatta gacttagata tgctcatgaa atcctggtca acattcaaca
     5641 caatatcgcc ttgtttttta gcatcttccg ttgcttctgc ttcaaattga tcatggagtt
     5701 tttgttgctc tggtgtatag tttttttatt tacacgattt aatgtactat tttttatttt
     5761 agtattaaga actccattaa tacgattttt aaattctgct tcaaaaaatc ccttaatttg
     5821 ttggtgcgca agttcaacat tcaaaccttt cttatacaag tcttcattct gatacaagtc
     5881 ttcattctga acgatttcgg ctacacggtg aatggtttga tcgtataccg tcttctctta
     5941 accagcagta tccttagttt taatgactac tcgataggtt cctttagaac cgttatagtc
     6001 atctagtttt aaaaaagcat tccaaacatt caaaaatagt tggaacttcc cttaataaat
     6061 ccgtcacttt ctttttcaag atagcccaag cttgctcaat aggattcaaa tccggtgaat
     6121 aaggtggtag aggtaagaaa aagtgtttat cttggatgca gagttcatcc aaaatgttct
     6181 tgggatgaaa actagcattg cccatgacaa taacatgagg tgtcttcaaa gcaggtagga
     6241 gttgcgtttt gaaccactcc acaaagaaat cgcttgtcat gcttttcttg taaatcatgg
     6301 gagctataaa ctctccgtct acttgtcctg caacaattga agttcgctca aaacgacgtc
     6361 cgctaatctt ttcatagact ttctcccctc taggagcccc tgcataagga cgatagaggt
     6421 agcggtcgat tcctgtttca tcaatatata cgattggtaa atcttttagg ttatccaaaa
     6481 tatcaagaaa ctcagcgact ttctctgact cttgttcctt aaagatcgtc atcttttttt
     6541 aaagtgacct taatctgctt taaagctgcc catactgaag gaacagcaca atcaaaatgt
     6601 gccgcaattt cccgtaaaaa agcatctgga tgagcctcta caaaggcttt caattcttct
     6661 aaagggatct tacgcttttt gacgactcgc tttttccgct ctaagttcct ttgttcacgt
     6721 ctttcttttc ccacgtgaag agagttctga cgccaacacc aaaaaacttt ggccgcctcg
     6781 acatgtctgt gccctccttt gatggaatct aatgctcctt gtttaaaatc agtattatat
     6841 gccatagctt tattagacca tgcttatttt aaactaagca actatatcaa tgttttgtta
     6901 tgagaagact tacttttttt actgaaattg aatttttcct agcctcaaca tcatataacc
     6961 ccaaaattca atctgacctg gtttgaagag atgttcgaag cagataaggt tttactaaaa
     7021 ctaaaaaaaa tgatataatc aaactgatta aatgttttaa aaataaagga gaatttgaat
     7081 gtcttaccaa gaaaattacc agaaatgggt tgattttgtg gagcttcctg actaccttcg
     7141 tcaagatttg gaaaatatgg acgaaaaaac taaggaagat gccttctata caaatcttga
     7201 atttggtact gcaggtatgc gtggcttggt tggtgctggt acaaaccgta tcaacatcta
     7261 cgttgttcgc caagctactg aaggattggc tcgtttgatt gagtcaaaag gtggaaacga
     7321 gaaagaacgc ggtgtagcaa ttgcctacga tagccgtcac ttctcacctg agtttgcctt
     7381 tgaatctgcg gcagttcttg ctaaacacgg catcaaatct tacgtatttg aaagccttcg
     7441 tccgactcca gaactatcat ttgcagttcg tcatctcaac tgtttcgcag gtatcatggt
     7501 cacagccagc cacaaccctg ctccatttaa cggttacaag gtttacggtg aagacggtgg
     7561 acaaatgcct ccacacgatg cggacgcttt gactacttat atccgtgcaa tcgaaaaccc
     7621 atttgcagtt gaagttgctg atgtggaaac tgaaaaagct tctggcttga ttgaagttat
     7681 cggcgaagct gttgacgtag aataccttaa agaggttaag gacgtaaaca tcaacccagc
     7741 cttgattgaa gaatttggta aagacatgaa gattgtctac acaccacttc atggtactgg
     7801 tgaaatgttg gctcgtcgtg ctcttgccca agcaggattt gactctgttc aagttgttga
     7861 agcgcaagca actgctgacc cagacttctc aactgtaaca tctccaaacc cagaaagcca
     7921 agcagccttt gcccttgctg aagaacttgg tcgtcaagtt ggtgcagatg ttcttgtcgc
     7981 aactgaccca gacgctgacc gtgttggtgt tgaagttctt caaaaagatg gtagctacct
     8041 caacctttca ggtaaccaaa tcggtgctat catggctaaa tacatcttgg aagctcacaa
     8101 aaacgctgga actcttcctg aaaatgccgc tctctgcaaa tctatcgttt caactgactt
     8161 ggtaacgaag attgctgaaa gctacggcgc aactatgttc aacgtcttga caggtttcaa
     8221 atttatcgct gaaaaaatcc aagaattcga agaaaaacac aaccacactt acatgatggg
     8281 atttgaagaa agcttcggtt acttgattaa accatttgta cgtgataaag atgccatcca
     8341 agccgttctt gtcgttgctg aacttgctgc ctactaccgt tctcgtggtt tgacacttgc
     8401 tgacggtatc gaagaaatct ataaagaata tggctactac gcagaaaaaa caatctctgt
     8461 tactctttca ggtgtcgatg gtgctgaaca aatcaaagag attatggcta aattccgcaa
     8521 caatgctcca aaagaatgga acgcaacagc tatcactgtc gtagaagact tcaaggcaca
     8581 aactgctact gttgctgacg gtactgttac aaacttgaca actcctccaa gtgatgtgtt
     8641 gaaatacaca cttgctgacg gttcatggat tgccgttcgc ccttcaggta cagaaccaaa
     8701 aatcaagttc tacattgcag ttgtagggga aaccaacgaa gaatcacaag ctaagattgc
     8761 taacatcgaa gcagaaatca atgcatttgt aaaataaaga cctataaaag atgagaccaa
     8821 ccaacctcat cttttttcgt atcaaatcta agcaatttta gaaactttat ggcatactag
     8881 acttatcaat gaaagcgagg taatctcatg gaacaatttt tagataacat caaagacctt
     8941 gaagtcacta cagttgtgcg tgcgcaagaa gctcttgata aaaaagaaac tgcaaccttc
     9001 tttatcggtc gcaaaacttg cccttactgc cgtaaatttg caggtacatt gtcaggtgtc
     9061 gtagctgaaa ccaaagctca catttacttc atcaatagtg aagaaccaag ccaactcaat
     9121 gatttgcaag cattccgctc acgttatgga atcccaactg taccaggttt tattcatatt
     9181 acagatggac aaatcaacgt ccgttgcgac tcttcaatgt cagcacaaga aatcaaagat
     9241 ttcgcaggat tgtaaaaaat cagctaacaa gtcttaaaat cacaaaaacg cataatgtaa
     9301 ggtgcaaaaa ccttgatatt atgcgtttta ttgttcctaa aacagttaca tcagtatttc
     9361 attacagaac attttaattt tggaagtcaa atcaattttt aacaatgttt tagaaatcac
     9421 agtgggctat tccatatt
//
LOCUS       DBEJKC010000068         9176 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.068, whole genome shotgun sequence.
ACCESSION   DBEJKC010000068 DBEJKC010000000
VERSION     DBEJKC010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9176
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.068"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..464
                     /locus_tag="ACL3G6_001830"
     CDS             <1..464
                     /locus_tag="ACL3G6_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="protein phosphatase 2C family protein"
                     /protein_id="HGR0546307.1"
                     /translation="RLPTFAFIFAKLSEKKLEYMMLGDCVMLVNEMEITDHRVDNLFE
                     KGKNEIKDPIGTNSVLNKKIILQKIRKLSNQPSGYWIGSLDERFLDHAIINQIDVTSE
                     QIVLMSDGFYEFYQNNQNKTFEELIKMRFNSSAIDPIYGKKDDASIVVIDV"
     gene            522..1061
                     /locus_tag="ACL3G6_001831"
                     /pseudo
     CDS             522..1061
                     /locus_tag="ACL3G6_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
     gene            1076..2551
                     /gene="galT"
                     /locus_tag="ACL3G6_001832"
     CDS             1076..2551
                     /gene="galT"
                     /locus_tag="ACL3G6_001832"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGR0546308.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGTDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYLYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFRFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            2564..3574
                     /gene="galE"
                     /locus_tag="ACL3G6_001833"
     CDS             2564..3574
                     /gene="galE"
                     /locus_tag="ACL3G6_001833"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGR0546309.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKPALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            3754..4413
                     /locus_tag="ACL3G6_001834"
     CDS             3754..4413
                     /locus_tag="ACL3G6_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HGR0546310.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            4438..5505
                     /locus_tag="ACL3G6_001835"
     CDS             4438..5505
                     /locus_tag="ACL3G6_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR0546311.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            5609..6619
                     /locus_tag="ACL3G6_001836"
     CDS             5609..6619
                     /locus_tag="ACL3G6_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0546312.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            6631..8322
                     /locus_tag="ACL3G6_001837"
     CDS             6631..8322
                     /locus_tag="ACL3G6_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0546313.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            8325..9035
                     /locus_tag="ACL3G6_001838"
     CDS             8325..9035
                     /locus_tag="ACL3G6_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HGR0546314.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         3168 a         1226 c         1781 g         3001 t
ORIGIN      
        1 atcgcttacc aacatttgct tttatatttg ctaaactttc agaaaaaaag ttggagtata
       61 tgatgctagg tgactgcgtc atgttagtaa acgaaatgga aataacggat catagagtag
      121 ataacttatt tgaaaaaggg aaaaatgaga taaaagatcc aattggtaca aatagtgttt
      181 taaataaaaa aattatttta caaaaaatca gaaaattatc taatcaaccg agtgggtact
      241 ggataggttc gttggatgag agatttttag accatgctat tattaatcaa atagatgtta
      301 ctagtgaaca aattgtttta atgagcgatg gcttttatga attctatcaa aataatcaaa
      361 ataaaacttt tgaagagtta attaagatga gatttaattc ttctgctatt gatccaatct
      421 atggaaagaa agatgatgca agtattgtag ttattgatgt ttgatatatt gtttaaaata
      481 ttaattgtta ctattgaact ttgttaagaa gaggtaccta aatgttaagg ttatatttag
      541 aaaatgaaat tatagaatta tcaaataatt tagagaccat ttgggtatct gtgcttgata
      601 aatatgagaa gttatttgaa tatttatcaa atgaagaacg aatagaattg attaaagaag
      661 atttaatcat aaatgagtca gttctaaatg ttgataaaaa aggatatgag ttaatttgtt
      721 tacaacatcc cgtttcatat gacttaagaa gaattattag tgtaataaaa atatcaactg
      781 acattgaacg tattggggat agaattgttg aaattttaaa aaatctacag attattcaaa
      841 ataatgaaat tttgaagaaa attatttcag aaataaaaat acttcatgaa gttatcggac
      901 tgcatatgaa tagggctata tcttgttata gagaggaaca atctggatgt ttagatatgg
      961 ttgttataca aaaacagaat gagatagaag agcttagtac aaatattgaa aagaaaataa
     1021 tgaattacat atttgaagat gatgggaatg tttctgaaat tagaaagaaa aatatatgaa
     1081 aacaattatt gataattttg ttgatagagt aattgaatac ggaatgtata atgaaattga
     1141 caaaatatat gtgaaaaata gagtactagc gttaataggt gaggagggaa ctgatcgcat
     1201 ttccgatgaa aatgacctga aacaaataaa agattactta gtggaaatcg ccttaaaaaa
     1261 cggtaaaatt aaagatttaa tcgaggaaaa ggaatgttta ggagcagagt taatgaattt
     1321 catagttcct ttacctagtc gattaaatga tattttttgg agttcatatg atatatcacc
     1381 tcaagaagca gttgaagagt tttataagtt aagtaaagat agtgattata ttaaaacttc
     1441 tgctattgct aagaatattg agtttcgagc atcaactaaa tacggagagc tagagattac
     1501 gataaatttg tcaaaacccg aaaaagatcc aaaaacaatt gctgctgaaa aattagtaaa
     1561 agccactaat tatcccaaat gtttactatg tatggaaaat gaaggatatc aggggcgaat
     1621 aaattatcca gcacgttcga atcatagaat tattcgattg aaacttggtg acgaagtatg
     1681 gggattccaa tattctccct acttatactt taatgagcat gcgatatttt taaatagtca
     1741 acatgtacca atggctatta cctctaaaac atttgaacaa ttattggaga ttgttgatat
     1801 tttgccagga tattttgctg gttcaaattc tgatcttcct atctcaggag gctccattct
     1861 tagtcataac cactaccagg gagggaaaca tattttccca atggaaaaag caaaatttga
     1921 gagtgaattt cgttttaaag actttgagga tgttaatgct ggtattgtaa aatggccaat
     1981 gtcagtaatt aggttacaaa gtgaaaataa aaatcgcttg ttagatttag ctactaaaat
     2041 tctaaataag tggagagaat attcagattt agaagtagac atcattgcta tgactgaaga
     2101 tgtcccacac catacggtga ctcctattgc tcgtaaagtg gacgggagat atgaattaga
     2161 tattgttcta agagataatc atactactga acagtaccca gatggtgttt tccatcctca
     2221 tcaagatgta caacatatta aaaaggaaaa tatcgggtta atcgaagtga tgggacttgc
     2281 gatattacca cctcgtttga aaccagagtt agaagaagtt ggaaaatatc ttttaggaga
     2341 ggataacgca attgcggatt atcatttaga atgggccgac caattgaaag aaaaatatcc
     2401 tcgcattaat aaagaagagg ttaatagcgt agttcaacac gaagcaggac aagtgtttgc
     2461 gagagttctg gaagatgcag gagtttataa gaatacaccg tctgggcatg aagcgtttat
     2521 gagatttgtt aagtcggttg gaattaatta ggaggaaaca aaaatggcaa tattggtaac
     2581 aggcggagct ggttatattg gtagccatac cgtagtagaa ttactaaatt taggaaagga
     2641 agtcatcatt gtcgacaacc tttcgaactc tagcatcttg gtgctagacc gtattgaagc
     2701 aattacagga atacgtcccg tgttttacga attagatgtt tgtgataaac cagcattgag
     2761 aaaggtattt gaacaagaat cgattgatgc tgcaattcat tttgcaggtt ataaagctgt
     2821 cggagaatcc gtgcaaaagc ctgtgatgta ctacaaaaat aatattatga gtacattggc
     2881 acttgttgaa gtgatgtcag aatttaatgt taaaaagatt gtcttttctt caagtgcgac
     2941 tgtatatgga attaacaatc agtcacctct aattgagact atgcaaacaa gtgcgacaaa
     3001 tccttatggg tatacgaaag tgatgcttga gcaaatttta aaagatgttc atgtggcaga
     3061 ttcagaatgg agtattgcgt tgcttcgtta tttcaatcca attggtgctc atgagtctgg
     3121 tttgattggg gaagatccct caggaattcc taacaacttg atgccctata ttgcacaagt
     3181 agcggtaggt aagctgtcag aactaagtgt gttcggaaat gattatgata cgcttgacgg
     3241 tactggtgtg cgcgattata tccatgtagt agatttagca ataggacata taaaagcttt
     3301 agaaaaagta tctgaaaaaa cagatgttta tatctataac ctaggctcgg gagaaggcac
     3361 tagtgtatta caacttgtaa atacatttga aagtgttaat aagatcccta ttccttataa
     3421 aatagttcca agacgttcag gagacgttgc aacttgttat gcaaatgcag acaaagcata
     3481 taaggaatta aattggagga caacaaaatc gattgaagac atgtgtagag atacatggaa
     3541 ttggcaatca aaaaatccca atggctataa ttgatgatac tgtctatatg agtgctgtat
     3601 tttggaaaaa ttacttaacc ttttaatgaa atgcatattt aatgaaagat aaattaaaaa
     3661 aaatgtttga cagcgcttga caaaggaaac ggtttcattg tataatgtaa acacaatgac
     3721 accgatgtca aatataaaaa agaaggtctt tatatgaaaa acttaacaaa aattaagttc
     3781 aaagaaaatg gggaatttaa tcatttccct gggaatacag ttgtagcaaa tctttatact
     3841 aaacaagatt tgatggaagt tgttgatatt attcaatcac gttatagaga attaccattt
     3901 atcgataagt ttactttaac tccaaggaat tctattcaca tgactgtaat tgaattgttg
     3961 tgccatgaaa atcgtgaaac ggagttttgg agcagtaatc ttcctctaga tacaccttta
     4021 caggaaatac atgattactt tgctaaacaa cttgaaattt ttccattgtt ggatgaagaa
     4081 attcatatgc gtataactga aatgggaaaa caaaacatac tagttgaacc tgcagatgaa
     4141 gcttctgcaa agagattaga agaaattcgt acttatgtct cagaaaaagc aggtgtttgt
     4201 ttccctaatc atgatagata tcaattccat atttcaattg ggtatcttcg gattcctcta
     4261 accgaagagg aggaagaaga gtttactaaa gtcagagcag aattaactga aattttatta
     4321 gagaagattc caactattac tgtaaaccgt attgactata ctgtatttga agatatgagg
     4381 caatttgttc catatcacga aaaatttaaa taaaataata aaaaaggaga acttatcatg
     4441 aaaaaaatga aagtttggtc tactgtactt gcaacgggag ttgctcttac tacacttgct
     4501 gcttgctctg gaggttcaaa ttctacgact gcttcttcat ctgaagaaaa agctgataaa
     4561 agtcaagaat tagttatcta ttcgaactca gtctcaaatg gtcgtggtga ttggttaact
     4621 gctaaagcaa aagaagctgg ttttaatata aaaatggttg atatcgctgg cgctcaatta
     4681 gcagaccgtg ttattgctga gaagaataat gcagttgcag atatggtatt tggaattggt
     4741 gctgttgact caaataaaat tagagatcaa aaattactag tacagtacaa gcctaaatgg
     4801 ttagataaaa ttgatcaatc tttatcagat aaagataatt attataatcc tgtgattgtt
     4861 caaccattag ttttaattgg ggcgcctgat gtaaaagaaa tgcctaaaga ttggactgaa
     4921 ttaggtagta agtataaagg taaatattca atttatggtc ttcaaggtgg tacaggacgg
     4981 gcaattctag caagtatctt agttcgttac cttgatgaaa aaggagattt aggcgtatca
     5041 gaaaaaggat gggaagttgc aaaagaatac tttgcaaatg cctatactct tcaaaaaggt
     5101 gaaagctcag ttgttaaagc gttagataaa gaaagcccaa ttcaatacgg tatgatctgg
     5161 ggttctggag cgttaattgg acaaaaagaa caaaatgttg aattcaaagt tatgactcct
     5221 gagattggtg taccatttgt aactgaacaa actatggttt taagcactag taaaaaacaa
     5281 gcgttagcta aagaatttat tgattggttt ggtcaatcag aaattcaagt agaatatagt
     5341 aaaaaatttg gatctattcc tgccaataaa gatgccctaa aagagttacc tgaagatacg
     5401 aaaaaatttg ttgatcaagt gaaaccacaa aatattgact gggaagctgt tggaaagcat
     5461 ttggatgaat gggtagaaaa agctgaatta gaatacgtaa aataagaaat aagagttatt
     5521 ttttatgtcc aagtctctct attatttcta aatttaagga agaaataaag agaggctttt
     5581 ggttttagta atagagggag ttagtgagat gattaaattt gataatattc aaattaaata
     5641 tggtgatttt gttgcaattg ataatctgaa tttagatata catgaagggg aattctttac
     5701 atttcttggg ccttcaggat gtggtaaatc aactactttg agagcattgg taggtttttt
     5761 agatccatca tcaggaagta ttgaagttaa tggaacagat gtcactcatt tggaacctga
     5821 aaagcgtgga attggtattg tatttcaatc ttatgcgcta tttccaacta tgactgtttt
     5881 tgataatatt gcatttggtt taaaagttaa gaaggtagct ccagatgtta ttaaagctaa
     5941 agtatcagca gtggcagcaa aaattaagat ctctgatcaa cagttacagc gtaatgtatc
     6001 agaattatct gggggtcaac aacaaagggt agcattggct cgtgctctgg ttcttgaacc
     6061 taaaattctt tgtctagatg aaccattgtc aaaccttgac gcaaaattac gtgtagattt
     6121 gagaaaagag ttgaaaagac ttcaaaaaga gttaggtatt actactttat atgttactca
     6181 tgatcaagag gaagccttga ctttatctga tagaattgca gtctttaaca atggatacat
     6241 cgaacaggtc ggtacaccag tagagattta tcataattct caaactgaat ttgtatgtga
     6301 ttttattgga gatattaatg ttttgaccga tgaaacagtc cacgaagtat tactgaaaaa
     6361 tacaagcgtt ttcttagagg ataaaaaagg ttacattcga ttagagaaag ttcgattcaa
     6421 tcgtgaaact gaacaagatt ttattctaaa agggacaatt attgatgttg agttttctgg
     6481 agttacaatt cactatacaa taaaagtttc tgaaagtcag attcttaatg taacaagtat
     6541 tgatagtcag gctgctatta gatctgtcgg agaaagtgtg gaattattta tcacaccatc
     6601 agacgttctg caattttaag gaggtgcagt atgcgtcata aattaaattt aaaagattgg
     6661 cttattcgtt tagggttaat ctggttctta gtaacattta ttatttatcc aaactttgat
     6721 ctagtagtga atgtatttgt aaaaggagga gaattttccc ttgatgctgt acatcgtgtt
     6781 ctaaaatctc agagggcact tcagagtatt atgaacagtt ttaagttagc attttcactc
     6841 attattacag ttaatgtcgt aggtattctt tgtgttctat ttacagagta ctttgatatt
     6901 aaaggtgcta aaattttaaa attaggttat atgacctctt taatttatgg aggagtggtt
     6961 ttagcgactg gatataaatt tgtctatggt ccttatggat tgattacaaa atttttacaa
     7021 aatgttatcc cttctttaga ctctaactgg tttattgggt atggtgcagt cttattcatt
     7081 atgacatttt caggaactgc taatcataca ttgtttttaa caaatacaat tcgaagcgtt
     7141 gactatcaca ctattgaggc tgctcgaaat atgggagcaa aaccatttac tgttttccga
     7201 aaagtagtgt taccaacctt aattccaact ctatttgcac ttactattat ggtttttctt
     7261 agtggtttat ctgcagtagc agcacccatg attgttggtg gtaaagaatt tcaaactata
     7321 aatccaatga ttattacatt tgcagggatg gggaattctc gtgatttagc tgccttactt
     7381 gcaattattt taggtattgc aactacaatt ttgcttacta tcatgaataa gatagaaaaa
     7441 ggtggaaatt atatttctat ctctaagact aaagcgcctc ttaaaaaaca aaaaattgcg
     7501 tctaagcctt ggaatatcat tgctcacatt gtagcatatg gattgttcac agttttcatg
     7561 cttccactaa tttttatagt attatactca tttacagatc cagttgcaat tcaaacaggt
     7621 aacttaacat tatcaaactt tactttagaa aattatcgct tattctttag taatagtgcg
     7681 gcattctctc cattcttggt cagctttatt tattctatta ttgctgcgac aacagcaaca
     7741 attctcgcag ttgtatttgc tcgtgttgtc agaaaacata aatctcgttt tgatttctta
     7801 tttgaatatg gtgctctact tccttggtta ctaccaagta cacttttagc agtaagttta
     7861 ttatttactt ttaatcagcc acaatttctt gtcttgaatc agattttggt aggtagtttg
     7921 gtaattctac ttattgcata tatagttgta aaaatcccat tttcttatag aatggtacgt
     7981 gctattttat ttagtgttga tgatgagatg gaagatgcag caagaagtat gggtgcttca
     8041 cctttttata ctatgatgaa ggttatcatt ccatttattt taccggttgt tctctctgtt
     8101 attgctttaa actttaactc tttattaact gacttcgact tatctgtatt cctttaccac
     8161 cccctagctc aaccattagg tattacgatt cgatctgcag gtgatgaaac agcaacatct
     8221 aatgcacaag ctctggtatt tgtttataca attgttctga tgattatttc tggaacggta
     8281 ttatacttca cacaaagacc ggggcgtaaa gtaaggaaat aatcatgaca gccactagtc
     8341 ttgggttatc aaatattgaa atagttgtca ggattgtttt atcagtagtc attggtagta
     8401 taattggttt agagagaggg agcaaatccc agcctgcagg catccgaact tatagtattg
     8461 tttgtctagc tgcatgtttg attatgatga cgaatgaata cgtatcttat aaatttggga
     8521 caggagatcc tacacgatta ggagctcaag ttatatcagg tgtgggtttt ctaggcgctg
     8581 gaacgattct tattacagat aaaaagaaaa ttacaggtct gacaactgca gcaggcattt
     8641 gggcttcggc aggaattgga ttagctattg gagtaggttt ttatgaggga gctcttttag
     8701 tagccatttc tgtttggggt gtgatatcca tgttccaacc actaaaaaaa tatctacaaa
     8761 atcgttctaa aatgattgaa ttgtatatag tagttaaatc tacagaagcc tataatcgtg
     8821 tattggttta ttgtgcagaa aatggtatca gaatgaccga ttcaagaaca gcgtttggag
     8881 atgttaattc tgacagaatt gaatactttg atgttccaga taaaaaaata gcgtcattta
     8941 ttactctgga attatcaggt agatttgaac atcttcgact gatggaagaa attgctaata
     9001 ttgtaggtgt tatttatgtc gaagaaatta gctgaaattt agtaaacaaa gggacagatg
     9061 tttttgtcct tttgtttttt agatatttta atcatctaat ttttgagtag atttttgctc
     9121 agaggttttt atgaaagatt ataaaatcaa ttttgattta ggtaaaatag aatatt
//
LOCUS       DBEJKC010000069         9136 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.069, whole genome shotgun sequence.
ACCESSION   DBEJKC010000069 DBEJKC010000000
VERSION     DBEJKC010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9136
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.069"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(179..649)
                     /locus_tag="ACL3G6_001839"
     CDS             complement(179..649)
                     /locus_tag="ACL3G6_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR0546315.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(666..2939)
                     /locus_tag="ACL3G6_001840"
     CDS             complement(666..2939)
                     /locus_tag="ACL3G6_001840"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HGR0546316.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSSQDVIREVVYVESRVDTDQKGLPDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            3285..6386
                     /locus_tag="ACL3G6_001841"
     CDS             3285..6386
                     /locus_tag="ACL3G6_001841"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HGR0546317.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     EIEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQVDD
                     SKKKLDVTLFSDLYRQVDQEVREGAFYYIKGKVQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHDSDQEMSRILDQYKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNGIVMKT
                     IYR"
     gene            6469..7476
                     /gene="pfkA"
                     /locus_tag="ACL3G6_001842"
     CDS             6469..7476
                     /gene="pfkA"
                     /locus_tag="ACL3G6_001842"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HGR0546318.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            7535..9040
                     /gene="pyk"
                     /locus_tag="ACL3G6_001843"
     CDS             7535..9040
                     /gene="pyk"
                     /locus_tag="ACL3G6_001843"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HGR0546319.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
BASE COUNT         2783 a         1589 c         2057 g         2707 t
ORIGIN      
        1 tacctacggc aaggcgacgt tgacgcggat tgaagagatt ttcgaagagt ataaatcttc
       61 ctaggataaa gcaaaacgca tagtatcaag ggttttcaac acttgatact atgcgttttc
      121 tgatgttaaa gactttctac cagttttttt aagcataatt gttagttgta gtcatttatt
      181 attcttcaaa gaaaaatggt ggggcgaatt ttttcagttc ttcaaagcac ttttgagcag
      241 tatctgcatc ttcacagatg ataagacaga catcattacc acaaagggta gcgatagcgt
      301 cagggaagct caaagtatca atgatagaac caaaggattg agccagtcca ggaagggttt
      361 ttagtaggac ttggtgttga actgggcgca tccagacaag ggcgtcttcc atgtagagtt
      421 cgagacgttt ttcccatttt gagatggaac cattgttaag aacataataa gcgctatctt
      481 cttcgcggac ttttgatagg ttcatatttt tgatgtcgcg tgagagggtt gcctgggtta
      541 cttgaatgtc gttcttagca agaagggctt gcaactcagc ctgtgtatga atcttgtttt
      601 ttgtgataag agcgcgtata agttggtggc ggtgttctga tttattcata ataatgtaac
      661 tccttttagc aaggtaaggt aagcatggac tgagcgaggt cgacagtcaa gtggtagtct
      721 gtattgtcac ggatggtgat ttcaaagtca gtagtataga ggactaaacg gagagtgtct
      781 ccttctttta gcttgtaaat agttggctgc agttcaaatt gaacgtccat ccattcatct
      841 gcagtaatat cctctactaa cagtaaatca tttctatttt gtaaattaag gtaacctttt
      901 gtcacgactc gttgtgcctc tggtctaaat ggcaattcac agagattttc caacatgtga
      961 tagcgaccgt tgtcaatggt tctagcactt aaaatagctg gataaggttg taggtatttc
     1021 ttttgcccaa attctagcag ttgggcagat aagagcccct tgtttgtact ggatttgata
     1081 cgaagattga gctgagcgcg accatttagg tggagatctt tagtcacagg aaggttaata
     1141 gtaatctgat tggctttccc ttgatagagc tctgtattga aggtttggta tgtcttacca
     1201 tagcgctcaa aatccttatc tgggtactgg ttttgaatag cttgctcttc ttgaccaagt
     1261 gagaaggttt cacagttttc ttgcccaccg aagttatcaa gtgataacca agtctgtgga
     1321 gctgtattgt cctgccagat aacagtagga agttgaaagt ctgtttcctg tcctagtaat
     1381 ttcttggtca ataaggcatt tatggactca cggaagtcaa ttgattgcca attgttcatg
     1441 taaacatgag caccattatg gaaaaagaga tgcttgtgta tatgagtagg aagagcatgg
     1501 aacatctggt aaacatgaag tggtttgaca ttccaatcct gagaaccatg agtaaagaca
     1561 acctctgcct ttactttatg ggcattgagc agataattgc ggtcatgcca aaactgattg
     1621 tagtccccag tttttcgatc tagctgagct ttcacttttt ctaagtcagc ttggtgagct
     1681 tcattgccac ggatatagtc gccagctaag agattacgag aataggttaa ctcagcaagg
     1741 gagtcaaagt cctcacctgg ataaccacct gggctagtca ccagaccgtt ttcacggtag
     1801 tagttgtacc atgatgaaat tcctgcctcg gcaatgataa cttctaaacc atcgactcct
     1861 gtagtcgcaa gaccattgga catggtacct agataggaaa gtcctgttgt agcaactttt
     1921 ccgtttgacc aatcagcctt gacttgacgc tggcgcgtgt gatcagtaaa ggcacggcaa
     1981 cggccgttaa gccaatcgat gacattttta taagcctcga tttgctggta gtctccatta
     2041 gtcatgaaac ctgtcgagtc tttggtacca acacctgaga catagagatt ggcaaagcct
     2101 ctcggaagga agtagtcgtt tagtgtatag ctagagttga tgtgagttag cttttcctca
     2161 gcctctgcta taagctcagc tttaccttgg ggttggacga gatttagttg aggtttctct
     2221 agctcaatct tgtgaggaag cttaacctca agctcgccct ccatcttgta gagagccttg
     2281 tcactagcct tgtcattggt tccctgatga taagggctgg ctgtcatgat ggcagggatt
     2341 tttccatcaa aacgagggcg aataatgcta acctttacta ggtctggtag ccctttttgg
     2401 tcagtatcga cacgagactc aacgtaaacg acttcacgaa tgacatcctg gctagaaaaa
     2461 gtagccaaac tcttgccgtt aaagtagtgg tagtcattat cctccggaat aagaccatca
     2521 ctaacaagtt ggtcgataag agtatttcct tttttggtgc gagtatttag taactgatag
     2581 agattttcaa tcaagtcacc atatataatg ggaaatccag tttctttacg aaaaacgtca
     2641 ctatcttcga agtcaaccaa ataagaaaag cctaaaagtt gaaaagcaac agtataaaaa
     2701 atatctgctg tcagttcatc ttctgattga aaaaatgtca gcaggtctgt ttttttatca
     2761 gctgctagga tagaaagtgg gtagttggtg tcttgataag tgaaaaagaa acgacgtaaa
     2821 aaggtttcaa gtgagtcttt gtgattggct gtattttgta aatcaaagcc acattttttt
     2881 agttcagata agacattttc ttttggaaaa ttgatataac tatattgatt aaaacgcata
     2941 gaacctccat atagaatgac agttaaggtt attatatcaa aaaaaaagca gaaagggaat
     3001 tgttaacttc aaaaggaaat aatccaataa aaatgaataa agtactaaat tcaatataga
     3061 gaacagagta acaataagaa taatagatag ggtataaaag ttctaggaga tttatattat
     3121 atgctttctg tttttatata caatatagta taaatataaa aatgatgaca aaaatacaaa
     3181 tgaatagaaa ataaattagt aagctgatga aatttttctc aagagaagcc atttataggt
     3241 gaaaatggta taatatagtg agaaggatag aggagaagtg taaattgatc gcacaactag
     3301 atacaaaaac agtctatagt tttatggaaa gcgtcatttc gatcgaaaag tatgtgagag
     3361 cagctaaaga atacggctac actcatttgg ctatgatgga tattgacaat ctttatggcg
     3421 ctttcgactt tctagagatt acaaaaaaat acggcattca tcctttgcta gggcttgaaa
     3481 tgacagtgtt tgtagatgat caggaagtga atttgcgttt tttagctcta tctagtgtgg
     3541 gctatcagca gttgatgaag ctttcgacag ccaagatgca gggggagaaa acttggtcag
     3601 tcctgtccca gtacctggag gatatcgcgg tcattgtgcc ttattttgat agagttgagt
     3661 cgttagaact aggctgtgat tactatatag gggtttatcc agaaacacta gcaagcgaat
     3721 ttcatcatcc tatcttacct ctttatcggg tcaacgcttt tgaaagcagg gatagagaag
     3781 ttcttcaagt tttaacagcg attaaagaaa atctaccgct cagagaagtt cccttgcgtt
     3841 cgagacaaga tgtctttata tcagcaagtt ctttagagaa actattccaa gagcgttttc
     3901 cgcaagcttt ggacaattta gaaaagctta tttcaggcat ttcttacgac ttggatacta
     3961 gtctgaaact gcctcgtttt aatccagcta gaccagcagt agaggagttg agagagcgtg
     4021 ctgaactggg gcttgttcag aaggggttga ctagtaaaga atatcaagat agactagacc
     4081 aagaattgtc tgttattcat gatatgggct ttgatgatta tttcttggtt gtttgggatt
     4141 tgttgcgttt tggacgatcg aatggctatt atatgggaat gggaaggggt tctgcagtag
     4201 gcagtttggt ttcttatgcc ttagacatca cggggattga cccagtagag aaaaatctga
     4261 tttttgaacg ctttcttaat cgtgaacgct ataccatgcc tgatattgat attgatattc
     4321 cagatattta tcgtccagat tttatcagat atgttggtaa taaatatggt agtaaacatg
     4381 cggcacaaat cgttactttt tcaacctttg gagccaagca agctcttcga gatgtcttga
     4441 aacgctttgg tgtgccagag tatgaattat ctgcaattac taagaaaatc agttttcgtg
     4501 acaatcttaa gtcggcctat gagggcaatc tccagtttcg tcagcaaatc aatagtaagt
     4561 tagaatacca aaaagctttt gagattgctt gcaagataga gggctatcca aggcaaacct
     4621 ctgtccatgc ggctggtgtt gtaattagtg accaagattt aaccaactat attcctctaa
     4681 agtatggtga tgaaattcca ctgactcagt atgatgctca tggagttgag gctagcggac
     4741 ttttgaagat ggactttctg ggactacgaa atttgacctt tgtccagaag atgcaagagt
     4801 tgcttgctga aatagaaggt attcacctta aaattgaaga aatagatttg gaagacaaag
     4861 aaacgttaga tttatttgcc tctggaaata caaaaggtat ctttcaattt gagcaaccag
     4921 gtgccattcg tctgcttaag cgtgtgcaac cagtctgttt tgaagatgtc gtcgcgacta
     4981 cttctctaaa tcgaccgggt gctagtgact atatcaataa ttttgtggca agaaagcatg
     5041 ggcaggaaga agtgactgtt ctggatccag tactggagga tattttggct ccaacctacg
     5101 gcataatgct ctatcaggag caggttatgc aggttgccca gcgacttgcc ggatttagtc
     5161 ttgggaaagc cgatattttg cgtcgggcta tggggaaaaa ggatgcctct gccatgcatg
     5221 agatgagggc ttcctttatt caaggttcat tagaagctgg tcatactgtg gaaaaagcag
     5281 agcaggtctt tgatgttatg gagaagtttg caggttatgg ttttaacagg tcacacgcct
     5341 atgcctactc agccttggcc ttccagttgg cttatttcaa aacgcattat ccagccattt
     5401 tttatcaggt catgttaaat tcttccaaca gtgattactt aatagatgca cttgaagcag
     5461 gttttgaagt agcctctcta tccatcaaca ccattcccta tcacgataaa attgccaaca
     5521 aggccatcta tctaggtttg aaatccatta aaggagtcag taatgattta gctctctgga
     5581 ttattgaaaa tagaccttat tctaacattg aagattttat agctaaatta cctgagaatt
     5641 atctgaaact tcctctgcta gaacctttgg taaaagttgg tcttttcgat tcatttgaaa
     5701 aaaatcgtca aaaagtattt aataacttag ctaatctatt tgaatttgtg aaagagttgg
     5761 gaagtttgtt tggagatgct atttatagtt ggcaggaatc ggaagattgg acggaacaag
     5821 aaaaatttta tatggaacaa gagcttttag ggataggtgt cagcaaacat ccactacaag
     5881 ctattgcaag taaggctatt tacccgatta ccccaattgg aaatttgtca gaaaatagct
     5941 atgctattat cttggttgaa gttcagaaga taaaagtaat tcgtaccaaa aagggtgaaa
     6001 atatggcttt cttacaggtg gatgacagta agaaaaaatt ggatgttaca ctcttctcag
     6061 atttatatcg acaggttgat caggaagtaa gagaaggagc attctactat atcaaaggga
     6121 aagtccagtc acgtgacggt cgtctgcaaa tgattgcaca agaaataaga gaagcagtgg
     6181 ctgagcgctt ttggattcag gttaaaaatc atgactcgga tcaagagatg tcacgtattt
     6241 tagaccagta taaaggccca atcccagtca tcatccggta tgaagaggaa cagaaaacca
     6301 tcgtttctcc ccatcatttt gtagctaaat ctgatgaatt agaggcgaaa ttgaatggaa
     6361 tagttatgaa aacgatttat cgctaaaaat acggaaaata gaagaatttt aaaatcaaat
     6421 gtgatataat caagaagaat gttaaaagaa aaaggagcat aaaccaatat gaaacgtatt
     6481 gctgttttga ctagtggtgg agacgcacct ggtatgaacg ctgctatccg tgcagttgtt
     6541 cgtcaagcaa tttcagaagg aatggaagtg tttggtatct atgacggata tgctggtatg
     6601 gttgccggtg aaattcaccc cctagatgca gcttcagtag gagacatcat ttctcgtggt
     6661 ggtacttttc ttcactcagc tcgttatcca gagttcgctc aacttgaagg gcaacttaaa
     6721 gggattgagc aattgaaaaa acacggaatt gaaggtgtag ttgttatcgg tggtgacgga
     6781 tcttaccacg gcgctatgcg tttgactgaa catggcttcc cagctattgg tcttccaggt
     6841 acaatcgata acgatatcgt tggtactgac tttacaatcg gttttgacac agcggttact
     6901 actgccatgg acgctatcga taagattcgt gatacatcat caagtcaccg tcgtactttt
     6961 gtaatcgaag ttatgggacg taacgctggt gatatcgctc tttgggctgg tattgcaact
     7021 ggtgctgatg aaatcatcat ccctgaagca ggcttcaaga tggaagatat cgtagcaagc
     7081 atcaaagctg gttatgaatg tggtaaaaaa cacaatatca tcgtcttagc tgaaggtgtg
     7141 atgtcagcgg ctgaatttgg tcaaaaactt aaagaagctg gagatacaag cgaccttcgt
     7201 gtaacagaac ttggacatat tcaacgtggt ggttctccaa ctgcgcgtga ccgtgttttg
     7261 gcgtcacgta tgggtgcaca tgctgttaaa cttcttaaag aaggtatcgg tggtgttgcg
     7321 gttggtattc gtaacgaaaa aatggttgaa aatccaattc ttggtactgc agaagaaggg
     7381 gcattgttta gccttactgc agaaggtaag attgtggtta acaacccaca caaagccgat
     7441 attgagctat ctagcttgaa taagagcttg tcataattta caatttagtt aataagacca
     7501 aaaaggtcat atatataaag gagtcacaaa aatcatgaac aaacgtgtaa agatcgttgc
     7561 aactttgggt cctgcggtag aaatccgtgg tggtaaaaaa ttcggtgagg atggatactg
     7621 gggtgaaaaa cttgatgttg aagcttcagc taaaaacatt gctaaattga ttgaagctgg
     7681 tgctaacaca ttccgattca acttctcaca cggcgaccac caagaacaag gtgagcgtat
     7741 ggcaactgtt aaacttgcgg aaaaaattgc aggtaaaaaa gttggtttcc ttcttgatac
     7801 aaaaggacct gaaatccgta cagaattgtt cgaaggtgaa gctaaagaat attcatacaa
     7861 aactggtgaa aaaattcgtg ttgcaactaa acaaggaatc aaatcaactc gtgaagtgat
     7921 tgcgttgaac gttgctggtg ctcttgatat ctatgatgat gttgaagttg gtcgtcaagt
     7981 tttggttgac gatggtaaac ttggtcttcg tgtggttgct aaagatgatg caactcgtga
     8041 atttgaagtt gaagttgaaa acgatggtat catcgctaaa caaaaaggtg tgaacatccc
     8101 taacactaaa attcctttcc cagctcttgc tgaacgcgat aacgacgata tccgtttcgg
     8161 tcttgaacaa ggtatcaact tcatcgcaat ttcattcgta cgtactgcaa aagatgtgaa
     8221 cgaagttcgt gcaatctgtg aagaaactgg aaacggacat gttcaattgt tcgctaaaat
     8281 cgaaaaccaa caaggtatcg ataacttaga cgaaatcatc gaagcagctg atggtattat
     8341 gattgctcgt ggtgatatgg gtatcgaagt accgttcgaa atggttccag tttatcaaaa
     8401 aatgattatc aagaaagtca atgctgcagg taaagttgtt atcactgcaa caaacatgct
     8461 tgaaacaatg actgaaaaac cacgtgcaac tcgttcagaa gtatcagacg tattcaacgc
     8521 tgttatcgac ggaactgacg ctacaatgct gtcaggcgag tctgcaaacg gtaaataccc
     8581 actcgagtca gtaactacaa tggctacaat cgacaagaac gctcaagctc ttcttaatga
     8641 atacggacgt cttgattcag attcatttga gcgtaactct aagacagaag taatggcttc
     8701 tgctgttaaa gatgctacta gctcaatgga tatcaaattg gttgtaactc ttactaagac
     8761 aggtcatact gcacgtttga tttctaaata ccgtccaaat gctgacatct tagcattgac
     8821 atttgacgaa ttgacagaac gtggcttgat gttgaactgg ggtgttattc caatgttgac
     8881 agatgctcca tcttcaactg acgatatgtt cgaaatcgct gaacgtaaag cggtagaagc
     8941 aggtctcgtt gagtcaggcg atgatatcgt tatcgttgct ggtgtgccag taggagaagc
     9001 tgttcgcaca aacacaatgc gtatccgcac agtacgttaa gaaaaatata aaaacctatc
     9061 atatccagct ttagagcttg tgtgataggc tttttgtata gagggtaaga aataggcaaa
     9121 actttcataa tggatt
//
LOCUS       DBEJKC010000070         8750 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.070, whole genome shotgun sequence.
ACCESSION   DBEJKC010000070 DBEJKC010000000
VERSION     DBEJKC010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8750
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.070"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            43..1266
                     /locus_tag="ACL3G6_001844"
     CDS             43..1266
                     /locus_tag="ACL3G6_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HGR0546320.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            2698..2982
                     /locus_tag="ACL3G6_001845"
     CDS             2698..2982
                     /locus_tag="ACL3G6_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546321.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            2975..3223
                     /locus_tag="ACL3G6_001846"
     CDS             2975..3223
                     /locus_tag="ACL3G6_001846"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546322.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLHATQDVD
                     AFYDQNQKINEIIARVGKQFNLNIHEELWLNNHVAKQI"
     gene            3319..3537
                     /locus_tag="ACL3G6_001847"
     CDS             3319..3537
                     /locus_tag="ACL3G6_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546323.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LESFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(3905..6229)
                     /gene="pflB"
                     /locus_tag="ACL3G6_001848"
     CDS             complement(3905..6229)
                     /gene="pflB"
                     /locus_tag="ACL3G6_001848"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HGR0546324.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            6577..7638
                     /gene="dinB"
                     /locus_tag="ACL3G6_001849"
     CDS             6577..7638
                     /gene="dinB"
                     /locus_tag="ACL3G6_001849"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HGR0546325.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILCAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSIAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(7785..8630)
                     /locus_tag="ACL3G6_001850"
     CDS             complement(7785..8630)
                     /locus_tag="ACL3G6_001850"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HGR0546326.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
BASE COUNT         2900 a         1644 c         1566 g         2640 t
ORIGIN      
        1 ttttcttatg tttaatataa aataaaccaa aggaggaaac aaatgattac aaaacaatca
       61 gcctttttac aaaatagagc cactatactg gagtttctat atcgaaatcc agcaacatcc
      121 cgtacagata ttgttaatga aacaggactt actccagcaa caacgactaa catcataaaa
      181 gagctaagcg aacagtccct catatacgaa actggtgatg aatttagcga gttttccgga
      241 tctggaagac gtagaaaaac tatttctatc acagataata ttccgtatgt tgttggaggt
      301 attgaaataa acgtcctagg tatctttctc agtctatgtg acttacaagg gaaaactctt
      361 ttcgagacag aaattttgaa tgaagattat cctatttcag aaatcaattc caccattacc
      421 aatatgataa aaacagctat agagtacgtc cctttggaaa caaaattact tggatttggc
      481 ttatcaatac ctggacatta taacaaagac tccggaagta tcattacaaa caaccccata
      541 tgggaatctt ttaatttatt aaatgtaatt aaaagattca attttccttt tattgtaaaa
      601 aataatatcg attgtatggc tataggacaa taccttttta atccacacaa tacccccgat
      661 aactttattt tcctgcacgc tggattaggt atttacactt cctttttcac aaaagaaaaa
      721 ataggagcct ctaaaaatcc ttatatcgga gaaattggac acaccattgt cgaattgaat
      781 gggcaatatt gtgaatgcgg aaaaaaaggt tgtttacaaa catatatttc ggatgcttgg
      841 ttaatcaaac acgcccaatt attatttaaa aattcccaac taactgtact aaaaagcctt
      901 gtaaagactg aaaaagacat tcatttagac acccttttaa cggcttataa tttaggcgac
      961 tccgctttac gtcaacaaat tgataaagga gtcaatttat tagccacttc tattgcaaat
     1021 ctcctcctca tcaatcctgc tgataaaatc tatatcaaca gtcaattgct taattatcaa
     1081 cctttcactc atgaagtcag ggataaaatc caagaccagc tccacttcgt tccctttact
     1141 cgtaatatag aaattgaaat tttaccttac aacaaacatc gtggaagtat aggagcttgt
     1201 gcattagcta tcgtcgcttt tttcatagaa catagcaatg tattacaaga tattatttca
     1261 ccttaatata ttagaaatct atagacctgt ttaaatcaac tataacctgt agtagatatc
     1321 tcgtatttag acaatatgaa aacaagacga cttccatata ggaaaccgcc ttctctctat
     1381 gttgagtgat ttatattaaa ataacttttc ttctagctgc attttattat tataaaaaca
     1441 ttcatcataa ccctgaactt aaataacgat ttttattcaa gatacatact cctagaataa
     1501 actttatatg aaattctcat ttttgttttt acaattctcc ttagttaaat cttgtttaat
     1561 atatgtttta catatagtat ttagcgccac atagtactga actctctcca aaaacggtta
     1621 ttcctctttg aatagggcgt tatcacaaga aaagcatctc cacgtttcaa cttcatatgg
     1681 ctcaaaaaca atcaattgat gctaaaacct gtacctagat gtttcggttc ataaaaccat
     1741 gaaactgtaa aagtggatga aattgatagc gatagtcaaa tcaagaggca tcataactct
     1801 aaaaagtcac aatatataag ttcatcctcg gaaaaatatc attctaattg ttgaaatgcc
     1861 tacatgaaaa gaaacgtcaa atactcatga aacaacgaat acaggtatca aaactatgac
     1921 aaaacaagtc cctaaattta ctaaagacac tgctcaactt tacacctgta aatggttgtt
     1981 gtataataaa gttacaaaga tgtacgacca cactgttgta aatcatagtg ttcgcgaata
     2041 tattactgat agcatttcta caaatacaat tgaagagact ggatagactt taaacgaaat
     2101 atgtcagtgt tttggcattc ctagccttca tatcatttaa agaattctat agacaaaatt
     2161 tttcccaata cagacactcg taacaactgc ttcatttttc taccaacata tttaggaaca
     2221 ggataagata caagaggatt aatccataga tcagttctat accaatctaa gacaaataag
     2281 ctaaaaaaac gattgataat aagcaaatag attccaaatt ttctctatct gctcatttta
     2341 ataaacaata ctagtgtaac tatccttcca gtcagaagct tgtcaaatca caccgaaaat
     2401 tcttctaaaa tttatctcgt taggcaatca agcaaaaact cgacgatagt acaaacatta
     2461 tcatacagaa ttgacttcct aaattatata ctttagtaag gttttcgtat aagaaaaaag
     2521 attcatttta catttctaaa cattcttttc taagatgaaa aacagaattt ttcgattgtg
     2581 atttaaagca acaagaagat tttcagtatc atcctataga tacgagctaa ttaagaaaaa
     2641 ctacattttc gaatataaac tacaataata taaactaaat tttataggag gaagacaatg
     2701 gattggtacg attatatgat acaggcatcc aaacaatcac aattcaacgc aagccattgg
     2761 tttcgctatt tgcgaaaagt tatttttgaa gactattctt atttaacaaa ccaagatgta
     2821 gaaaagttgc tagactccaa agaactaacc cgttttcaaa aaattagctt gaagtatgcc
     2881 tttcaagagc atactccaac tcataaatat gtgatttcat taaataaacc tgctaagtta
     2941 accaatgttc aaaaattgat ggagaaatac aaacatggat aaaatgaaac cggtcttcca
     3001 agccctaaat aaggaattaa ttcaggaaaa tctgacttta acaattatct gtgtcgatgg
     3061 ttatgtctta gaatatcatg gtttacatgc cacacaagat gttgatgctt tttatgacca
     3121 aaatcagaaa atcaatgaaa ttattgctcg tgtaggaaaa cagtttaatc ttaacatcca
     3181 cgaagagtta tggctcaaca atcatgttgc aaagcaaata tgaacaaaca acctccctta
     3241 agtttatgcg aatccttgta ctcatttgag aatctgaccg ttttagtagt ccctattgag
     3301 tatgtgttag gaatgaagat gatgagtatc agagagcagg atttgcaaga tattggtgca
     3361 attattaaat acaaaaactt tcattcacca ttcgatacct ttaaatattt aaaagacatg
     3421 ggatttgata ctattgacct ctctgttcta ttagaaagtt ttagttatgc ttatggtatg
     3481 gattggttag aaaaattttt taaagaaaat caagataaac ttcgcgaatt ttattaacag
     3541 tatcaaacaa gatgattgtc aattagccag tcgtcttgtt ttttatgatg aaatgaaata
     3601 aaatctgaac aaatcgctta gagaattcca gtcaatttct agcgctgttt gagacgtttc
     3661 agtggactat agtaaaatga aataagaata ggacaaatcg atcaggacag tcaaatcgat
     3721 ttctaagaat gttttagaaa taaaggtgta ctattctagt ttcaatctat tatatttcag
     3781 attcggtcca ctattccttc ccaaaaacat tgcatattgc gccgaaggaa ttgctcatac
     3841 tatcccaagc acaaaaccct cagtcgtttg accgagggtt cctttttatt attcaagaac
     3901 ttgattagct caatgcatcc aaggcgtcat ccattgaaag aacttcgtgg aagacacgtt
     3961 gtgtcaattc agttttttgt tctggagtga ggtatttagt gtttacacag tatccagaga
     4021 tacgtacgat aacgtcttcg cctgacatga ttttttcgta aacatcgttc aagtccataa
     4081 cgttcaagtt aacgtgttgt ccaccgtttt cgaagtaacc atcaaggatt gttaccaagt
     4141 tatcaacttg ttcatcacga gtcttaccaa gagcgcgagg tgatacttgt gtagtcaatg
     4201 agataccgtc agctgcataa ctaaagtcaa ggctagaaag tgagttcaag ttttgcaacc
     4261 aaccaccttt agctttgtta gatgggttag cacctggtga gaagaattca agtttagaca
     4321 agttcacaga accatcttcg ttgaggtata cacctttgtg aactggtgag ttaccagttt
     4381 gtttagagta agcaacgtta gatgtgattg tcaaaagtga tactgtagct tctgcgtctt
     4441 tgtatagttt gtggctacgt agacgagttg tgtaagcttc gatcaaccat tctgccaatt
     4501 cgtttgaacg tgggtcatct tcaccccagc gtgggtagtc accgattgtt tcgtaatcgt
     4561 agatgtagcc atcttcgtca cggattggtt taactgtagc gtatttgata gctgacaatg
     4621 tatcaacagt gttagcaaat ccacagatac cgaatcccat gttggcacgt tgtttagttg
     4681 gcaagaaggc catttgaaca gcttcgtagt tgtacctatc agtcatgtag tggatgatgt
     4741 tcaaggcatc tacgtaagtg tcagtcaacc agtcaagaga tttttcaaag ttcgctttaa
     4801 ctgattcgaa ttcaagaact tcgtcacgga ttggttcgat atcaaatact ttgtagtctt
     4861 tgtgaacatc gtcgtaacca ccattcaaac cagtaagaag ggctttaaga acgtttacac
     4921 gagcaccgaa gtactggatg ttgtggcgtt gttcttcatt ttctggatca agtggagaca
     4981 cacagcatga gatacagctc atttcaccat atccgtcttt agccattgtt gttacacctt
     5041 cgtattggat agaagagtgt ttgtggctca tgtgcataca gtagcgacgg aagttgtatg
     5101 gcaatttgtc agtccaaaga actgtcaagt ttggttctgg tgagttaccg atgttgtcaa
     5161 gagtgttcaa gaaacggtag tccatcttag taacacggtg acgaccgtcg ttacccatac
     5221 cagccataga agttgtgata aaggttgggt cacctgagta caattggtca taagctttgg
     5281 tacgagcaaa tttaactgta cgaagtttca taacgaaatc atcaacgaat tcttggattt
     5341 ctgattcagt aaatgtacca cgagcaaggt cacgttctgc aaagatgtcc aatacgattg
     5401 gtacacgacc tagagatgta gcagcaccgt taatcacacg gcagacagcc atgaaagcaa
     5461 tgttaaccca ttggattgct tctttcacgt tcatcgctgg tttgcgaaca tcaaccccgt
     5521 aaaggtcacc caggcgaaca acttgttgca atgcttggta ttgaaggttt acttcttcac
     5581 gaagacggat tgtttcttca tcgatttctt tgattgcatt ccagtcattt actttttctt
     5641 gcatcaagta gtctgcaccg taaagagcaa gacgtgcgta aacaccgatg atacgtccgc
     5701 gtgagtatgc atctggaaga ccagttacag tgtgtgcgtg acgagcgcga cgaatatttg
     5761 aagtgtaggc acggaaaata ccgtcgttaa ctgttgttac atatttagtg aagatttcgt
     5821 gaacagctgg gtctggttcg tatccatttt ctttcaaagt agtttcagcc atacggatac
     5881 caccttttgg catgaagttc aatttgaaga gttcatcgtt ttggataccg aagataactt
     5941 cattttcttt gtcgataaat ccagcaggga tatcagcgat agatgttgga cgagtgtcca
     6001 ttgggaaacg agtttcttcg tagtgtgctt tagtttcttc tacaattttc ttgatgtgaa
     6061 gtgaacgctc tgttggtcct gcaaggaagc tttcgtctcc atcataaggt gtgtagttag
     6121 cttgtacaaa tcgtgataca cttgcttttt ctttccaatc tacgcctttg aagccttccc
     6181 aagctttgtc aaaaatatct tgtgcttcaa caactgtctt aacaaccata ttaatgtcct
     6241 cttttttcta gtaacagtca tctgttacat tcataagaca agtataccat atagtaaccg
     6301 atttcaacaa gtgaaaattc cctattttta cactttcttt tctaaaacag tctatatttt
     6361 atttcaaact gtattatatt tttgaaaaaa taaagtcctt ttttcttttt ttcagaaaaa
     6421 agggtataat aaaagaaaat aagcagtaac actcaatgga aatcgaaaag caaactagga
     6481 agctagccgc agattgctca aaacactgtt ttgaggttgc agatagagct gacgtggttt
     6541 gaagagattt tcgaagagta taaaaaggtg ctaggcatgt tgatttttcc tttgttaaat
     6601 gatttgtcaa gaaaaatcat ccatattgac atggatgcct tttttgctgc agtggaaatc
     6661 agggataatc ctaaactcag aggaaaacct gtcattattg gaagcgaccc tcggcaaaca
     6721 ggtggacggg gagtcgtttc tacctgtagt tatgaggcaa gagcttttgg tgtccattct
     6781 gccatgagtt ccaaggaagc ttatgaacgt tgtccccagg ctgtctttat ctcagggaat
     6841 tatgagaaat acaagtctgt gggactccag attcgagcta tttttaagcg ctatacagat
     6901 ttgattgaac ccatgagcat tgacgaagcc tatttggatg tgacagaaaa taaactcggt
     6961 atcaagtcag cggtcaaaat tgctcgcctc attcaaaaag atatctggca agaactccat
     7021 ctaactgctt ctgccggtat ttcctataac aagttcttag ctaaaatggc gagtgattat
     7081 caaaaacctc atggtttgac agtgattcta cctgaacagg ctgaggattt tctcaaacaa
     7141 atggatattt ccaaatttca tggagtagga aaaaagacag tagaacgtct tcatcaaatg
     7201 ggcgttttta ctggtgctga tttacttgaa gttcctgagg tgaccctaat agaccgtttt
     7261 ggtagactag gctatgatct gtatcgaaag gctcgtggca ttcacaactc tccagtcaaa
     7321 tccaatcgca tccgtaaatc aatcggcaag gagaaaacct acgggaagat tctctgtgct
     7381 gaggaagata tcaaaaaaga gctgactctt ctatcagaaa aagtcgctct caatctacat
     7441 caacaagaaa aagctggaaa aattgtcatt ttgaaaatcc gctacgagga cttttcaact
     7501 cttaccaaac gaaaaagtat tgctcaaaaa acacaagatg ctagtcagat aagccaaata
     7561 gccctgcaac tctatgaaga attaagtgag aaagaaagag gtgtccgcct attggggatt
     7621 accatgactg gattttaaag ctcaatgaaa atcaaagagc aaactaggag gctagccgca
     7681 ggctgctcaa aacactgttt tgaggttgca gataaagctg acgcggtttg aagagatttt
     7741 ctaagagtat aaaaccttga agagttgccc cttcaaggtt tttcttatac aaataaacgg
     7801 acaaaactgt aaagtagcaa aacactacca agcacgatac ggtatttacc aaaaagggtg
     7861 aagtcgtgtt ttttcacata gctggtcaag aagcgaatag ccaccatgct gaccgcaaaa
     7921 gctactccca tcgcgaccaa gagcaaaaac aattgcccaa agctcaagag ttctccggct
     7981 ttcacaaatt tgaaaatctt taaggcacta gctccaaaca taacaggaat cccaagatag
     8041 aaggtaaatt ctgtcacaac tgaacgactg gttccattta acaaaccacc gacaatcgtt
     8101 gcacctgaac ggctagtccc tggtaaaaga gcaagaactt ggaagagtcc gatatagaaa
     8161 gcggtcgtat aaggaagctt gtccaactct gttacacttg gctcgatagc acgcgcttta
     8221 ttgcgctttt ccaaatagat gaaggcaacc ccgtagataa tcaacatgag agcaactgaa
     8281 accatgttat ggaagtgggt atcaaaccaa tcatcaaatt taaagacacc aagtaaaggt
     8341 aaagtagcaa tcaagacctt caaccatagt ctccaagtct tacgaacttc ctgtttgtcc
     8401 ttagtcggtt taaaaggatt gagcttgtta aaataaatca ccataactgc taaaatagca
     8461 ccaagctgaa tcacgacatt aaacatggac ataaaggctt cattttgatt ttggtattgg
     8521 atgaattcct ctgctaaaat caagtgacct gtactggaaa tcggcaacca ttccgtaatt
     8581 ccttcaacaa tcccgaagaa gatagatttt aaaatttcaa taagatacat agattactcc
     8641 ctatattata attagcgcag ttagctactg ccaaagccca agtggtatac ttggaataag
     8701 ccactgtgga ttagttcatt tcctccaatc gcttgacgat ttccgaaagg
//
LOCUS       DBEJKC010000071         8686 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.071, whole genome shotgun sequence.
ACCESSION   DBEJKC010000071 DBEJKC010000000
VERSION     DBEJKC010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8686
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.071"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..333
                     /locus_tag="ACL3G6_001851"
     CDS             <1..333
                     /locus_tag="ACL3G6_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HGR0546327.1"
                     /translation="LRKETQIEEKKLPLFGTPGFYETNLNLLNNQPEDIMGLVLLLYW
                     SQNLDDFNVFSKMSFLEAMEYAMNFNSRRLDTLDKSDWLYDIYKKAFNYKYDTFSELK
                     KDFIEVLK"
     gene            365..1264
                     /locus_tag="ACL3G6_001852"
     CDS             365..1264
                     /locus_tag="ACL3G6_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGR0546328.1"
                     /translation="MNNVSVRYDDVIALKDITLQINKGDFIGLLGSNGAGKSTLINSI
                     VGFQEIYLGEIEYCDKDLIVSSQPFAHLGFTPQTTVIDFYTTVKDNVILGLNLAGKFG
                     KNAEKLCQIALEIVGLADKKNNLVETLSGGQLQRVQIARAIAHNPDFYILDEPTVGLD
                     TESAEKFLMYLKDKSLEGKTIIISSHDINLLEKFCKKILFLQNGSISFFGDMRDFVDN
                     STIKLNFSMQNRISRYQIEFLENFRFKVHIEDNDSFTIEVPIEENILDVINEVGKACE
                     IKNFSTSKLTLQESYLQRIGGEK"
     gene            1261..2061
                     /locus_tag="ACL3G6_001853"
     CDS             1261..2061
                     /locus_tag="ACL3G6_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0546329.1"
                     /translation="MKADQLRHKSDLGLRGLAIIAKNEIIAFFRSKGLIISQFLQPIL
                     YVVFIIIGLNSSIKNIQFNDIKTSYAEYTIIGVIALLIIGQMTQVIYRVTIDKKYGLL
                     ALKLCSGVRPLYYILGMSIYSILGLIVQEIIIYIITLAFEINIAMDRFFYTVLLSIVV
                     LLFWDSLAILLTMFINDYRRRDIVIRFVLTPLGFTAPVFYLIDSAPSIVRWIGQLNPL
                     TYQLTILRNFYFKNSTTLELVFLLLTSLLVLISVSFIIPKIKLILIER"
     gene            2219..2692
                     /gene="tnpA"
                     /locus_tag="ACL3G6_001854"
     CDS             2219..2692
                     /gene="tnpA"
                     /locus_tag="ACL3G6_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISSpn6 family
                     transposase"
                     /protein_id="HGR0546330.1"
                     /translation="MREDNQSLSHTTWNCKYHIVFAPKYRRQIIYGRYKASIGRIIRD
                     LCERKGVIIHEANACSDHIHMLISIPPKLSVSSFMGYLKGKSSLMIFDKHANLKYKYG
                     NRKFWCRGYYVDTVGRNQKVIAEYIQNQLQEDRVADQLTLFESVDPFTGEINKRK"
     gene            2949..3170
                     /locus_tag="ACL3G6_001855"
     CDS             2949..3170
                     /locus_tag="ACL3G6_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0546331.1"
                     /translation="MYRRLRDLREDHDLTQKQIATILSFTNSAYAKIERSEHALTADV
                     LVKLSDFYDVSTDYLLGLTDFPDKIRFRK"
     gene            3472..3705
                     /locus_tag="ACL3G6_001856"
     CDS             3472..3705
                     /locus_tag="ACL3G6_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000693750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGR0546332.1"
                     /translation="MEIKYVSVENSVAEWADKKSILKRWEGLNLYTLNRWIKEMRENK
                     RFSLYVINPTHKLVFINLEGFECFLRWKQKRTK"
     gene            3781..5289
                     /locus_tag="ACL3G6_001857"
     CDS             3781..5289
                     /locus_tag="ACL3G6_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0546333.1"
                     /translation="MYYVTKTNSKGQPLYQVVEKYKDPLTDKWRTVTVSYTRNTSRAR
                     KQAEREVMDKIEKLTSSLESQYNPEMITTFGELKESWFQTWCVSVKPQTIKREELVIE
                     RLGKIIGDEFLLDRITPLLMKNCLNKYLDKYDASPSTMTHIKSTCNKIFNHGVLYNVI
                     KYSPMTAVKIDVPLEKKRESRKRLDAKFLAIHELQAFFDVLGQCRNASYYDLAIVLLL
                     TGIRIGEAAFLPSDVDFDKGILHIDKALQYHDLKVDEFYFDTTKTVNADREVALPIAA
                     SEAIQRTIKRNQEFEAYMEQNPSPAFKKCDSVFQTEYGSPITSHSFRQVLKRVEEKLL
                     KNCQKDYGFKWVKHVTPHSFKHMHISYLQSNEMHIAVKDIMTRVGHANFETTMGYTHN
                     ISRSQENTVTALNQFVEKHNFHFKELKSYTCKYSRMIEQFIETCDDNNKVELSVDEFK
                     DLLHLGSRYSPKHIVSNLLLKIKKDIVKYHPQFDIKIVKLSGNQIKGFSISW"
     gene            5370..6221
                     /gene="ylqF"
                     /locus_tag="ACL3G6_001858"
     CDS             5370..6221
                     /gene="ylqF"
                     /locus_tag="ACL3G6_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HGR0546334.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEKAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            6208..6987
                     /locus_tag="ACL3G6_001859"
     CDS             6208..6987
                     /locus_tag="ACL3G6_001859"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HGR0546335.1"
                     /translation="MATIKEIKEFLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQVVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            7003..8553
                     /locus_tag="ACL3G6_001860"
     CDS             7003..8553
                     /locus_tag="ACL3G6_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HGR0546336.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
BASE COUNT         2839 a         1412 c         1727 g         2708 t
ORIGIN      
        1 ctaaggaaag aaactcaaat tgaagaaaaa aagttgcctc tatttggaac tccagggttt
       61 tatgaaacca acttaaattt attgaataat caaccagagg atattatggg attggttttg
      121 ttattatatt ggagtcagaa tttagatgat tttaacgtct tttcaaaaat gagtttttta
      181 gaagcgatgg agtatgcaat gaattttaat tcgcgtcgct tagacacact tgataaatca
      241 gattggcttt atgatattta taaaaaagcg ttcaattata aatatgatac tttttctgaa
      301 ttaaaaaaag attttataga ggtattaaaa taaaggtagg ggtgttatga attgtttctt
      361 gaaaatgaat aatgtaagtg ttcgttatga tgacgtaata gctttaaaag atataacttt
      421 acaaataaat aagggagatt tcattggctt attaggttca aatggtgcag gtaaatctac
      481 gttaattaat tctattgtag gttttcaaga gatttattta ggagaaatag agtattgtga
      541 taaagatttg atagttagtt ctcaaccttt tgctcattta ggctttactc ctcaaaccac
      601 agtaattgat ttttatacta ctgtgaagga caatgtaata ttggggctga accttgctgg
      661 aaagtttggg aaaaatgctg agaagttgtg tcaaatagcc ttagaaattg ttgggttagc
      721 tgataaaaaa aataatttgg tagaaacatt gtcaggtgga caactgcaac gcgtccagat
      781 tgctagagca atagctcata atccagattt ttatatttta gatgaaccta ccgttggttt
      841 agatactgaa tctgccgaaa aatttttaat gtatttaaaa gataagagtt tggaaggaaa
      901 aactattatc atatcttcac atgacataaa tctactcgaa aagttttgta aaaaaatact
      961 ttttttacaa aatggctcca tatcattttt tggtgatatg cgtgactttg tagataattc
     1021 aactatcaaa ttaaattttt caatgcagaa tagaatttct agatatcaaa ttgaattttt
     1081 agaaaatttt agatttaaag ttcacatcga agataatgat agttttacaa tagaagtccc
     1141 tatagaagaa aatatcttag atgttatcaa tgaggtagga aaagcatgtg aaattaaaaa
     1201 cttttcaaca agtaaattaa ccttacaaga aagttatttg caaagaatag gaggagaaaa
     1261 atgaaggctg atcaattaag gcacaaatcg gacttaggtt taagaggtct agcgattatt
     1321 gctaaaaatg agattattgc tttttttaga agtaaaggtt taattatttc tcagtttcta
     1381 caaccaatct tatatgttgt ttttataata ataggattaa attcttcgat aaagaacatt
     1441 cagtttaatg atataaaaac ctcttatgca gaatatacaa tcattggtgt tatagcttta
     1501 ttgataatcg ggcagatgac tcaagttatt tatagggtga caatagataa aaaatatggg
     1561 ctacttgctc ttaagttatg cagtggagtt cgtcctttat attatatttt agggatgagt
     1621 atctattcta tattagggtt gatagttcaa gaaattatta tatatataat tacgttagcg
     1681 tttgagataa atatcgcaat ggatagattt ttttatacag ttttgttatc tattgttgtt
     1741 ttattatttt gggactccct tgcaatttta cttacaatgt ttatcaatga ttacagaaga
     1801 cgtgatattg taatacgttt tgtactaaca ccgcttggtt ttacagctcc tgttttctac
     1861 ttaatagatt ctgctcctag tattgtgaga tggattggtc agttaaatcc cttaacttat
     1921 caattaacta ttttgagaaa cttttatttt aaaaattcaa caactttgga attagttttc
     1981 ttattgttaa catcattact tgtccttata tctgtatctt ttattatacc aaagataaaa
     2041 ttgatactga tagaaagata aaagttgggt catccaactt ttttgttgtc tcccgaaaac
     2101 cactagctat gctagtggtt ccatagagct tttagcgtgg taacaaaaag aacctcctaa
     2161 aatgataaga tagaagtggt ttctccgcca ctacaacata tcatacagga ggtacctcat
     2221 gagagaggat aatcaaagtt tatcacatac cacatggaat tgtaaatatc atattgtttt
     2281 tgcacccaaa tatcgtcgtc aaatcattta tggcagatac aaagctagta tcggaagaat
     2341 catacgtgac ttatgtgagc gtaagggtgt aataatccat gaagcgaatg cttgttcaga
     2401 ccatattcac atgcttatca gtattcctcc gaaacttagt gtttcgtcct ttatgggcta
     2461 tttaaagggc aagagcagtt tgatgatttt tgataagcat gcgaatttaa aatacaaata
     2521 tggcaatcgc aagttttggt gtagaggcta ttatgtagat acggtaggcc gtaatcagaa
     2581 agtgatagct gaatatattc agaatcaatt acaagaagac agagtagcag accagctcac
     2641 gttattcgag tcagtagatc cgtttactgg cgaaataaat aagaggaagt aactaaggtg
     2701 ctttagcacc tgctcgggaa agtggtgcgc gaggaagcta tttcggtggg cctttggccc
     2761 tggccggtag aagcggctta tagccgcaga acaaaccacc agttcacact ggtggttttg
     2821 atttaaaaaa cttgatacat aaaaataaaa gtctatataa aggatggtaa aattcctgtt
     2881 gtccgatttg gacaatatcc taaatagtta caatatatgg tctatacttt ttcttaggag
     2941 aaagctagat gtacagacgt ttgagagatt tgagggagga tcatgatctg acccaaaagc
     3001 aaatagctac aatactttcg tttacaaatt cagcttatgc caaaattgaa cggagtgagc
     3061 atgcgttgac ggctgatgta ttggttaaac tctcagattt ctatgacgtc agtacagact
     3121 atttattggg attaactgat tttcctgata aaattcgctt tagaaaataa tctcctcaat
     3181 ttcatagagt ttgaaaatga gtgagatttt ttatttgccc tttgacaact gaatagccta
     3241 aaatggtact ttcctcattt gtggagcagt tttgcttgat tcgccaagat aggagcgggg
     3301 acaatcacca ataaaataga gcgatactct atctgccatg atgcaaatga tatacaatga
     3361 tacttctgaa cgttcaggct gccgtcgtaa aagagcagta agtgagattc ttatgatgac
     3421 cccatcagtc atgccatgga gggagaagaa attattcgaa aggatgataa tatggagata
     3481 aaatacgtat ctgttgaaaa ttcggtagct gagtgggcgg ataagaaaag catactgaaa
     3541 cgatgggaag gtttgaatct ctacactctt aacagatgga tcaaagaaat gagagaaaat
     3601 aagagatttt ctttatacgt catcaatcct acacataagc tggtgtttat aaatcttgag
     3661 ggattcgaat gctttttgag atggaaacaa aagcggacaa aataaggaag tcatggtata
     3721 atatagagta gttatttatt ctatacaaca atgatttatt tcttttcgag gaattaaatt
     3781 atgtattatg taactaaaac aaattcaaaa ggacaaccct tgtatcaagt ggttgaaaaa
     3841 tataaagatc cacttactga taagtggaga acagtaactg tcagctatac tagaaatact
     3901 agtagagcac gaaagcaagc tgaaagagag gtaatggata aaatagaaaa actgacctct
     3961 tcccttgaaa gtcagtacaa tcctgaaatg attacaactt ttggagagtt aaaagagagt
     4021 tggtttcaaa cttggtgcgt atctgtcaag ccccagacaa taaaaaggga agagttggtg
     4081 atagaacggc ttggtaaaat tatcggtgat gaatttttac tcgatcgaat tacaccacta
     4141 ctgatgaaaa attgtcttaa taaatatctg gataaatacg acgcttcacc ttcaacaatg
     4201 acacatataa aaagtacgtg taacaagata tttaatcacg gtgtgctata caatgtcatt
     4261 aagtactctc caatgaccgc tgttaaaata gatgtgcctc tggagaaaaa gagagaatca
     4321 agaaaaaggc ttgatgctaa atttcttgca attcatgaat tgcaagcctt ttttgatgtt
     4381 ttagggcagt gtagaaatgc tagctattat gaccttgcta ttgtattatt actgacaggg
     4441 attcggattg gagaggctgc ttttttacca tcagatgttg attttgataa ggggatttta
     4501 catattgata aggctctcca atatcatgat ttaaaagttg atgaatttta ttttgatacg
     4561 actaagaccg tcaatgctga tagagaggta gccctcccaa tagcagcgag tgaagcaatc
     4621 cagagaacta taaaaagaaa tcaggaattt gaagcctata tggaacaaaa tcctagtcct
     4681 gctttcaaaa agtgtgatag tgtatttcaa actgagtatg gttctccgat aacttctcac
     4741 tcatttcgtc aagttttgaa gagggttgag gagaagttgt taaaaaattg tcagaaggat
     4801 tatggtttta aatgggtcaa gcatgtgacc cctcattctt tcaaacatat gcacattagt
     4861 tatcttcaaa gtaatgaaat gcacatagct gtaaaggata ttatgactag agttggtcat
     4921 gcgaattttg aaaccacgat gggctacacc cataacatca gtcgttcaca agaaaatact
     4981 gtaactgctt taaatcaatt tgtagaaaag cacaattttc actttaaaga attgaagagt
     5041 tacacctgta aatattcgag aatgattgaa caattcattg aaacttgtga tgataacaat
     5101 aaagtagagt taagtgttga tgaatttaaa gacttattac accttggttc acgttactca
     5161 cccaaacata ttgtttcaaa tttactgtta aaaatcaaaa aagatattgt caaatatcac
     5221 ccacagtttg atataaagat tgtgaaatta agcgggaatc aaatcaaagg tttttccatt
     5281 tcgtggtagt tttggtgttc gcttggtgtt tagacgatag taaaataaat gaggggtgct
     5341 aaacccttgc tacgaaagga aaaaactcaa tggctactat tcaatggttt cctggtcaca
     5401 tgtctaaagc tcgtcgacag gtgcaggaga atttaaaatt tgttgatttt gtgacgattt
     5461 tagtagatgc acgcttgcct ctatctagtc aaaatcctat gttgaccaag attgttggtg
     5521 ataaaccaaa actcttgatt ttaaacaagg ccgacttggc tgatccagca atgaccaagg
     5581 aatggcgtca gtattttgaa tcacaaggaa tccagacgct agctatcaac tccaaagagc
     5641 aagtgactgt aaaagttgta acagatgcgg ccaagaagct catggctgat aagattgctc
     5701 gccagaaaga acgtgggatt cagattgaaa ccttgcgtac tatgattatc gggattccaa
     5761 acgctggtaa atcaactctg atgaatcgtt tggctggtaa aaagattgct gttgttggaa
     5821 acaagccagg ggtcacaaaa ggtcaacaat ggcttaaaac caataaagac ctggaaatct
     5881 tggatacacc ggggattctc tggcctaagt ttgaggatga aactgttgca cttaagttgg
     5941 cattgactgg agctatcaaa gaccagttgc ttcctatgga tgaggttacc atttttggta
     6001 tcaattattt caaagaacat tatccagaaa agctggctga acgcttcaaa caaatgaaaa
     6061 ttgaagaaaa agcgcctgtg attattatgg atatgacccg cgccctcggt ttccgtgatg
     6121 actatgaccg tttttacagt ctcttcgtga aggaagtccg tgatggcaaa ctcggtaact
     6181 ataccttaga tacattggaa gacctcgatg gcaacgatta aagaaatcaa agaattcctt
     6241 gtgacagtca aggagttaga aagccctatt tttttagagc ttgaaaagga taatcgctca
     6301 ggagttcaaa aggaaatcag caagcgtaaa agagccatcc aagctgaatt agatgaaaat
     6361 ttgcgcttgg aatccatgct ttcttatgaa aaagaacttt ataagcaagg attgacctta
     6421 attgcaggta ttgatgaggt tggtcgtggt cctcttgctg gtcctgtagt cgctgcggcc
     6481 gttattttac ctaaaaattg taagattaaa ggtctcaacg acagcaagaa aattcctaaa
     6541 aagaaacatc tggagatttt ccaagtcgtt caagaccaag ccttgtcgat tggaattggt
     6601 atcatagata atcaggtcat cgaccaagtc aatatctatg aagcaaccaa actagccatg
     6661 caagaagcaa tctcccagct cagccctcaa ccagagcacc ttttgattga tgccatgaaa
     6721 ctggacttgc ccatttcaca aacctccatt atcaaaggag atgccaactc cctctctatc
     6781 gcagcagcat ctatagtagc caaggtaaca cgtgatgaat tgatgaagga atacgatcag
     6841 cagttccctg gctatgattt cgctactaat gcaggatatg gcacagctaa acatctggaa
     6901 ggcctcacaa aactaggagt taccccaatt caccgaacca gctttgaacc cgttaaatca
     6961 ctggttttag gtaaaaaaga aagttaattg aaaggaaata ccatggagga acaatcggaa
     7021 atagtccgtt ctaagaaaga attcgccttt gcatccagca ctatactatc ccaagttggt
     7081 cgaggaatca ttgtcggcct catcgttgga attatcgtcg gatcctttcg tttcttaatt
     7141 gaaaagggct tccacctgat acaaggagtt tatcaagatc aagggtactt agtgcgcaat
     7201 ctttttgtac tggttttgtt ttatatactc atctgttggc tcagtgccaa actaacacgg
     7261 tcagaaaaag atattaaagg ctcaggaatt cctcaagtcg aagccgaact gaaaggcctc
     7321 atgtccctca actggtgggg cattctttgg aaaaaatatg tgctaggtat tcttgctatt
     7381 gccagtggac tcatgctggg tcgagaggga cccagcattc aacttggagc agttggtggt
     7441 aaaggaattg ccaagtggct caaatccagt ccagtagagg aacgttcctt gattgctagt
     7501 ggagctgcag caggtttagc cgcagccttt aatgctccta ttgcagcact tctctttgtt
     7561 gtagaagaag tctatcacca tttttcgcgc tttttctggg tctcaactct agcagccagc
     7621 atcgtagcaa actttgtgtc tctactcatg ttcggtttga caccagtatt ggatatgcca
     7681 gataacattc ctcccatgac cctagaccag tattggatat atctcgtcat gggaattttc
     7741 cttggatttt caggttttct ctatgagaaa gctgtattaa acgttggaag agtttatgac
     7801 ttgattggtc aaaaaatcca tttggatagg gcttattatc ccatcttggc ttttatcctt
     7861 atcataccag tcggaatctt cttacctcaa atcattggtg gcggaaatca gcttgtcctt
     7921 tctttaactg aacaaaattt tagtttccaa gttttattag cttacttttt gatccgcttt
     7981 atttggagta tgattagcta tggaagtgga ctgccaggag gaattttcct ccccatttta
     8041 gctcttggtt ctttgcttgg tgccttagtt ggtgttatct gtgtcaatct tggacttgtc
     8101 agtcaagagc aattccctat atttgtcatt ctaggaatga gtggctattt tggagccata
     8161 tcaaaagctc ccttaaccgc tatgatcctc gtaactgaga tggtaggaga tattcgcaac
     8221 ctcatgccac ttggtcttgt cactcttgtt tcttatatta tcatggattt gctcaaaggt
     8281 acgccagtct atgaagccat gctggaaaaa atgcttccag aagaagtatc tagcgaagga
     8341 gaagttacac ttatcgaaat accagtttct gataaaattg ctgggaaaca agttcatgaa
     8401 ctcaacttac cacacaacgt cctcatcaca actcaagtcc ataatggcaa gagccaaaca
     8461 gttaacggct caaccagaat gtatctgggt gatatgattc acctggttat tccaaaaagt
     8521 gaaattggaa aagtcaaaga tttgttgttg tagtatgagc atttacataa tttatgttat
     8581 gtaaatgctc agcttgattt atttagaaaa ccgattctca gaaatgagat cggttatttt
     8641 ttactgatga ggaattttac atataaataa ttgaacttta ttaaaa
//
LOCUS       DBEJKC010000072         8150 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.072, whole genome shotgun sequence.
ACCESSION   DBEJKC010000072 DBEJKC010000000
VERSION     DBEJKC010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8150
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.072"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(52..1464)
                     /gene="sufB"
                     /locus_tag="ACL3G6_001861"
     CDS             complement(52..1464)
                     /gene="sufB"
                     /locus_tag="ACL3G6_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HGR0546337.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVICELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(1518..1958)
                     /gene="sufU"
                     /locus_tag="ACL3G6_001862"
     CDS             complement(1518..1958)
                     /gene="sufU"
                     /locus_tag="ACL3G6_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HGR0546338.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            complement(1945..3171)
                     /locus_tag="ACL3G6_001863"
     CDS             complement(1945..3171)
                     /locus_tag="ACL3G6_001863"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HGR0546339.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAIEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPAIARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            complement(3182..4444)
                     /gene="sufD"
                     /locus_tag="ACL3G6_001864"
     CDS             complement(3182..4444)
                     /gene="sufD"
                     /locus_tag="ACL3G6_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HGR0546340.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKINYLERLESRGEGSAKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            complement(4472..5242)
                     /gene="sufC"
                     /locus_tag="ACL3G6_001865"
     CDS             complement(4472..5242)
                     /gene="sufC"
                     /locus_tag="ACL3G6_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HGR0546341.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            complement(5392..5586)
                     /locus_tag="ACL3G6_001866"
     CDS             complement(5392..5586)
                     /locus_tag="ACL3G6_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HGR0546342.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            complement(5614..7269)
                     /gene="dnaX"
                     /locus_tag="ACL3G6_001867"
     CDS             complement(5614..7269)
                     /gene="dnaX"
                     /locus_tag="ACL3G6_001867"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HGR0546343.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLAGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            complement(7269..7766)
                     /locus_tag="ACL3G6_001868"
     CDS             complement(7269..7766)
                     /locus_tag="ACL3G6_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HGR0546344.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            7960..>8150
                     /locus_tag="ACL3G6_001869"
     CDS             7960..>8150
                     /locus_tag="ACL3G6_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGR0546345.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     DCGSLMKKYDFQKPSKIPYL"
BASE COUNT         2369 a         1843 c         1515 g         2423 t
ORIGIN      
        1 ggcgatgctg acgtggtttg aagagatttt cgaagagcat aaaatcaaat tttatccaac
       61 tgatccctcc atttcatagc taatcaagcg gttcagctca actgcgtatt ccattggaag
      121 ttcttttgta aagggttcta caaatcccat gacaatcatt tcagttgcct cagattctga
      181 caatccacgg ctcatgagat aatacaattg ctcttctgaa atcttagata ctttggcttc
      241 gtgttccaaa gccacttgcg agttgtgaat ttcattaaat ggaatagtat ctgatgctga
      301 caagtcatcc atgataatgg tatcacattc aatgtgggaa acagatttct tagagttctt
      361 gttaaaggtg acttgtccac ggtagtcaac ctttcctcca cctttagcga tggatttaga
      421 cacaatagac gagctggtat gtggagcatt gtgaatcatc ttagcacccg tgtcttggtg
      481 ttgccctgca ttagcaaagg cgatagagag catggtacca cgcgctcctt ctccatcaag
      541 gtaaacagat ggatatttca tagtcgtttt ggcacccaag tttccatcaa tccactcaac
      601 agtggcatcc ttttgagcct tagcacgctt tgttaccaag ttatagacgt tatcagacca
      661 gttttggata gttgtataac gcatataagc tccgtccaaa gcaaaaattt ctacaatggc
      721 agcgtgtaag ctattgcttg aatatgttgg tgctgtacat ccttctacgt agtggacgct
      781 tgctccctca tcaacgataa tcaaggtacg ttcgaactga cctatatttt cgttattgat
      841 acggaaataa gtttgaagtg gaatatctac cttgacacct tttggcacgt agataaaagt
      901 tccacccgac catactgctg agttgagggc tgccaacttg ttatctgtcg gcggtaccaa
      961 cttcgcaaag tattgtttaa ataagtctgg gtattccttg agtgcggaat ctgtatctgt
     1021 aaagataata cctaattttt ggaactcttc cttcatgttg tggtaaacca cttctgactc
     1081 gtactgggca gaagcccctg ctaaataagc acgttcagct tctggaatcc cgatacgttc
     1141 aaaggtttct ttaatctttt caggtacatc atcccaagaa cgggctggtt tgtcagatgg
     1201 tttttggtag tagattaagt catcaaagtc aatctctgac aagtctgctc cccaagtttg
     1261 catgggcatt tttttgaagg tttcataaga cttcaaacgg aactccaaca tccactcagg
     1321 ctcaccctta gcagcagata attcacaaat aacaccttcg ttgagtcctt ttcctgtcga
     1381 taagacaggc tctacatcgt catggaaacc aaatttatat tcaccaaggt caattggttt
     1441 tggttctact ctttcttcag ccataatatc ctttctttct tcatttctaa taattcataa
     1501 gacaaaagaa acttgtctta ctgtttttct tgattttcaa ttgttttctt aagggcattc
     1561 caagctaggg ttgcacactt gattctttga gggaatttgg caacacctga caagaatgcc
     1621 gcgtctccaa gttggtcttg acgctcatct ttttgccctt gaaccatttc agaaaaaata
     1681 gtcgccagtt ctaaaatttc ttgtttggtt tttcctaaaa cggcatctgt catcatacta
     1741 gcagaagcag ttgaaatcgt gcatcctgaa tttagaaaag caatatcttc caaacggtcc
     1801 tctgcatcaa acttgacaga gaggttgatg acatccccac aagtcggatt gttgagactg
     1861 atttgctcag cgtcttctaa cttcccttgg tgatgtggat ttttcgaatg gtctgctacc
     1921 actgccatat aaaggctatc tagtttagaa agtgccattg aaaaactcct ttgtcttttg
     1981 tagggcatcg actagtttgt cgcaatctgc cttggtattg tagatataaa aacttgcacg
     2041 agctattgct gggacttcca aatactgaag caagggttgc gcacaatggt gaccagcacg
     2101 aacagccact ccttcataat ccagagccgt cgcaagatcg tgaggatgga gatcacctag
     2161 gttaaaggca ataacacccg aacgttgagc caaatcctga gaaccgtaaa tggtcaatcc
     2221 ctcaattgcc tgcagttttg gatagacgta cgcaatcaat tcctgttcat gagcttcaat
     2281 ggcatccata ccaatctttt ccagataatc aactgcagtc gcaagtccaa tagctcctgc
     2341 catatttggc gttccagcct caaatttcca aggcaattcc ttccaactag cagattgctc
     2401 gtagacaaaa tcaatcatct cgccgccaaa ttctactgga gacatttgct caagatactt
     2461 ttctttgccg taaaggacac cgataccagt cggaccagcc atcttgtgac ccgaaaaggc
     2521 gaaaaagtcc agatccaagt cctggacatc aatcttcata tgaggtgtag attgagcacc
     2581 atccactacc atgattgccc caacttggtg ggctaattga gtgatttcct tgatcggatt
     2641 gaccacacca agaacattgg aggcatgagc tagggaaaca aatttaacct tatcagtcaa
     2701 tttagctcgc aaatcctcca tatccaaggc accgtcttta agatagacat agacaagctc
     2761 tgctccagtc tttcgacaag cttcctgcca tggaatgata ttagaatggt gttccattac
     2821 tgaaatcaag acctggtctc cctcagtgag aatttcctca gcaaagcgtg ccacccagtt
     2881 aaggctggtt gtcgttcctc tggtaaagag aacttccttt gtagagcctg cattaataaa
     2941 cttacgaatg gtttcacgag cagcttcata agaagctgtc gctcgttccg ctaaggtatg
     3001 gacaccacgg tgaacattgg cattgtcctg ctcatagtag ctgttaatag ctttcagaac
     3061 tactagtggt ttttgtgtcg tcgcagcatt gtccagatag accagaggtt catcattgac
     3121 aatctgatct aaaattggaa aatccttgcg aatcgcttct acatctaaca taggctgccc
     3181 cttagcgttt tgacaatttc tcttcgatag ttgcaatcat ttcatcacga acttccttga
     3241 ctggaatctc cacgataaca gatccaagga aaccacgaac aaccaaacgc tctgcagttg
     3301 ccttatccaa tccacgactc atgaggtaat acatgtcttc tggatcaact tgtccgatag
     3361 acgctgcgtg tcctgcagtg acatcatttt catcaatcaa aagaattggg ttagcatctg
     3421 aacgcgcttg gtctgaaagc atgagaacac ggctctcttg ttgggcatct gctcccttag
     3481 cacccttgat gatgtggccg ataccattga aagtcaaagt tgctttttca aggataaccc
     3541 catgttgtag gatatttccg atagagttgc agccatagtt agttacacga gtatcaatcc
     3601 cttgtacctg acgaccactt gaaagagcta caaccttgag gtcagcatgg ctaccattac
     3661 caatcaagtc actatcaaaa tcagcaacga catttccttc gttcatgaca ccgatagccc
     3721 agtcaatact tgcatcgttg cctaatttac cacgacggct aatgtaggca gtgacgtttt
     3781 cacctagtcg gtcgatagca gcaaacttga cttgcgcacc tgaacgtgca atcacttcta
     3841 ctgtgatatt agcagttgct ttggcacttc cttcaccgcg tgactctaaa cgctccagat
     3901 aattaatctt agaattttta ccagcgataa tcataatatg cttgttaaac ggcacattgc
     3961 tatcgctatc ttggtagaaa attccttcaa ttggctctgt gatttctacg ttatctggaa
     4021 tatagagtac agcaccactg ttaaagtaag ctgtgtggta agccgccaac ttgtcatcat
     4081 catacttaac agatgacatg aagaattctt cgatcagctc tggaatttct tctaaagctg
     4141 agtgaaagtc tgtgaagaca acaccctgtt cagctaactc aactggagtt tgttcgaaaa
     4201 cagtttgagt tcctacttgc accaacttca agtgatgatc taaagctgtg aaatctggaa
     4261 catttgctga tggctcattt tctgtaatcg ttccatcacc cagattccaa cggtggaatt
     4321 tgacacgctc aataactggt aattccaaag tctcaatctt gtcaaaagct ttttgacgga
     4381 gatcagccaa ccagcttggt tcagcgtgca tttctgaaaa aagtttaata ttttctctag
     4441 tcatttactt ctcctaaaag atacgaggga attacaattc ttccttgtag tcgtagccaa
     4501 gttcttcagc taattttgcg tatccttcac gttccaaacg cgcagccaat tctggaccac
     4561 cagaaaggac aacacgacct tccatcatca cgtgtaccac atcaggtgtg atatagttca
     4621 aaagacgttg gtagtgagtg atgatcatag caccaaaacc ttcaccacgc atggcattga
     4681 cacctttaga cacaacttta agagcgtcaa tatcaagacc tgagtcaatc tcgtccaaaa
     4741 gagcaaatgt tggctccaac atcaaaagtt gaagaatttc attgcgtttt ttctcaccac
     4801 cagagaagcc ttcgttgagg taacgctctg ccatttcttc tttcatgtta agcaattcca
     4861 ttttttcatc tagcttagta ataaactcac gaactgaaat cttctcatca tcttctttac
     4921 ccgcattcat agcggcacga agaaattcag cattggtaat tccagggatt tctgatgggt
     4981 attgcatagc aaggaaaagt cccatacgcg cacgctcatc cacttccaac tcaaggatgt
     5041 ttacgccatc aaacaaaact tcacctttag ttacttcata gtttggattt cccatgatag
     5101 cggcagaaag agtcgattta cctgtaccat ttggtcccat gatagcggca atttctcctg
     5161 ttttcagggt caggttaacc ccttttaaaa tttcttttcc ttcaatctca acgtgaagat
     5221 ctttgatctc tattactgac atgatagttc ctttcttttt caaaactttt acagtactta
     5281 ctagaaaaac gtctgatttc cccagaaata gagcaaaaat tctataaata tacttttcta
     5341 gtataacaaa aaaaagccta aaaggctttg attttgtctg gaagctgagg gctagtcttt
     5401 cctattaaaa tgctgatcga tgacatcaac gattttaccc atcacataac tgactcggaa
     5461 atttctaaag agtaaaattg cccaaaaggc tgccataata tagcggccag tcatccaggc
     5521 ttcattgaaa aaataggtct cagcagctgt aaatagcgcc ataataataa attgttgttt
     5581 attcataaac ttattgtatc atgaaatctt tctttagtct tcctctacct tcactttatc
     5641 agccaaaaat tcaaatcctt ctggaatcag gctttcttct acttcttttt cagtttgaga
     5701 agatttggct ttggctgaaa aggctgcgcg aacttctttc cattcctcca tggaaatagc
     5761 taaaatctca ggtgaaaaac ctgccgcctg actgaggata ttaccaaaca tggtattgag
     5821 attgtctcgt ttcatagttt gaccagcatt gaagttagac tcaaaagcaa gaatagcatg
     5881 gtgttcattg gcagcaaccg gttgagaacc agctagcaga gccttgtccg gcccacctag
     5941 actttcaatt acctctcccc aggcattctg caaacgaatt aaattttgac gtgctaaatc
     6001 aggattttcg acggcctctt gtaagataga ttgcacttta ttgcgatcga cacgatagac
     6061 tgttttgccc gtagctggtc gactaggagc tggtgcaact tgtttaggaa ccgcacctgc
     6121 attagaaagc tcttgtttga gacgggcaac ttcctgtctc agcgtagcaa tttcattttc
     6181 aaccgctcct gatagagctg gttcgggctt gatttccgcc aaacggacgg tcatcatttc
     6241 agcataaatc ttgggctgca aactagactt aatatctgct aaattcactg ttgctaagcg
     6301 aatcatttca aacagatttt tttgaggaag tgccaaattt tctacaaaga ctgaactatg
     6361 atgagtattt tctccccctg tttgaacaat taacaagtct cttaaatagt gcaaaagatc
     6421 ggtcacaaaa cgagtcatgc tcttaccatt gtcaaaaaga agattcaagc aagacaaagc
     6481 tttgggaaca tcctgttgag acaaggccgc cacataatca tccaaggctg ataggctaat
     6541 ggtgccagta atttcttcag agatagcagt cgtcagctca tttccctgtg tcaaactcag
     6601 ggcttgatcc aaaatagaca aggcgtcccg cattccacct tccgcccgtc tggcaatgat
     6661 ttccacagcc tctggttcag aactgatatt ttctttttct aagatatagt gaatatgttc
     6721 cttaatatcc tgtgtcttaa ttgatttaaa ctcaaaacgt tgcacacggg atagaatagt
     6781 agcaggaatc ttgtgcaatt cagtagtggc caaaataaag actacattct gtgttggttc
     6841 ttccaacgtc tttaggaggg cattaaaagc ccctgtagac agcatgtgaa cctcatctat
     6901 gatataaacc ttataacgag caaggctagg cgcataggta gatttatcac gaatttcgcg
     6961 aatttcatct accccattat tagaagctgc atccatttca atgacatctt ctaaactacc
     7021 gtccgtcact gcttgacaaa tatagcagtt attgcaaggt tcgccaccca cttgattggg
     7081 acagttcata gccttggcaa agattttagc aacactggtt tttcccgttc cacgaggacc
     7141 agaaaaaaga taagcgtgac ttattttctc ttgctccacc gcttgtttaa gagtcttagc
     7201 cacaacttct tgaccaacta actgggagaa gttttgactt ctatattttc gataaagtgc
     7261 ttgatacatt aagatttttc ctcaaacatc gtaaagtccc atgttgtctt ttcaagcaaa
     7321 atagcgacaa attgttccaa ataatctcga tccatagcat cgtaatcctc aatctctgaa
     7381 gaatccagat ccagaactcc aagtaactga ccattcttca tcatcggcac cacaatttca
     7441 cttttagcta gactatcaca agaaatatag ttgagatagg tcgtcacatc tccaacaata
     7501 acagtttcct gaaagtgagc tgcctcacca caaaccccct tgcctagtgc aatacggatg
     7561 caggaaacac ctccttggaa ggggcctaaa accaattcct ttccatcgaa caaataaaag
     7621 cctgcaaata cggtattagg aaaacgtgat tttatgagag cactggcgtt ggaaagatta
     7681 gccaaaacat tggtttcgcc ttccaatagg aaggacaatt cttcatttaa catttgataa
     7741 cgtgattgtt tttctgattt taacatagaa ctattatatc aaaaaaggag cagagacaaa
     7801 agaaaaatcc cttgtttagt aaacaaagga ttttggactc tataatattt gtagtgggta
     7861 aatccactat agatattatg gagcctattt ttgtgtagaa aaaaagtccc atatgaccta
     7921 taatgaaaag cgacaaaaca actcattaga aagaatcata tggaacaatt acattttatc
     7981 acaaaattac tagacattaa agaccctaat atccagattt tagacatcat caataaagat
     8041 acacacaagg aaatcatcgc caaactggac tacgacgccc catcttgccc tgattgtgga
     8101 agtctaatga agaaatatga ctttcaaaaa ccgtctaaga tcccttacct
//
LOCUS       DBEJKC010000073         7676 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.073, whole genome shotgun sequence.
ACCESSION   DBEJKC010000073 DBEJKC010000000
VERSION     DBEJKC010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.073"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..743)
                     /locus_tag="ACL3G6_001870"
     CDS             complement(<1..743)
                     /locus_tag="ACL3G6_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HGR0546346.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTTKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGFLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMT"
     gene            complement(758..1606)
                     /locus_tag="ACL3G6_001871"
     CDS             complement(758..1606)
                     /locus_tag="ACL3G6_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HGR0546347.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(1603..3078)
                     /locus_tag="ACL3G6_001872"
     CDS             complement(1603..3078)
                     /locus_tag="ACL3G6_001872"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HGR0546348.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(3401..4756)
                     /locus_tag="ACL3G6_001873"
     CDS             complement(3401..4756)
                     /locus_tag="ACL3G6_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0546349.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMAYKTEL
                     S"
     gene            complement(4766..5083)
                     /locus_tag="ACL3G6_001874"
     CDS             complement(4766..5083)
                     /locus_tag="ACL3G6_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0546350.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEKTSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(5100..5417)
                     /locus_tag="ACL3G6_001875"
     CDS             complement(5100..5417)
                     /locus_tag="ACL3G6_001875"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0546351.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(5432..6328)
                     /locus_tag="ACL3G6_001876"
     CDS             complement(5432..6328)
                     /locus_tag="ACL3G6_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HGR0546352.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(6331..7593)
                     /locus_tag="ACL3G6_001877"
     CDS             complement(6331..7593)
                     /locus_tag="ACL3G6_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0546353.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDILLYLPFVIAIEKRFKLLED"
BASE COUNT         2641 a         1693 c         1076 g         2266 t
ORIGIN      
        1 gtcattccca tgacaaagaa taacatccct ttaaaacagt atcttaccca attttcaggt
       61 aagacttttg atacaaccgt ccccaatacc cctccgcata tagaagcaag aaaaataact
      121 ggaacaggtg ctaaatgata ctgatttaaa cctgtaacca caacaattgt agccaaatga
      181 gacaactggg aaaagaaaat aattgcaaga gaatacatcg ttgcttcttt tatcgaaata
      241 gaaaaaaaca ccatcaataa agatacattg agcggaccac caccaatccc taaaaaacta
      301 gaaatcaagc ccaatagaaa accacaaatc atatagaatc ctatcttatc aaattgataa
      361 gtttttttaa aatctgttaa aacaaatgat acaagtagca tcacaaatag taaaatcatt
      421 tgaacaatgg atactagccg tactgataat tgagataaca aaacttgaaa aataagatga
      481 cctagaaacc ctcctaaaac agaagaaaag gataccgtaa aaatcaatct ccattttatc
      541 tctttacttt gtgaaaatct tttggttgtt gaaataatcg ccattataaa aacagagaaa
      601 ctagaataaa aagcaatatc actgaccgaa tggtatccaa aactatccat aagtggctta
      661 attataattc caccacccat gcctgatata gaacccaatc cactagctat tataatgatt
      721 agaaaataaa taatctcaac cactttttaa gtccatccta ttctttcaaa catctaaaac
      781 ctagatggct actagtggaa gtagaaatac atccatttct agcagctact cggtatcgat
      841 tacaataaga acaatgacat aaaaaggaac ctcctctgat agcatactcc tcatcttgta
      901 tcccatattt tggcaactca tagtcatctt cattaaaact agctaataag gtatatctcg
      961 gattgcgaca ccattcccaa acattcccaa tcatttgata tagaccaaaa tcattaggta
     1021 aaaattcata gacaggagcc gttcctataa atccatctaa ggcagtattt tcataaggaa
     1081 atcttccttg ccaagtattg gcatgataat atccaccttc taaaagagta tctccccaag
     1141 gatattcaga ttgtcttcct cctctagcag catattccca ctgtgcttca gtcggtaaag
     1201 acattccgct ccaattacag aaagccaatg catcttctaa agcaacatga actactggat
     1261 ggtcttctaa acccactaga ttactattct caccgtaggg atgtttccag caagcgttcg
     1321 gaacttgtaa ccaccacgga gccccagcag gatgaggata tccctccctt tctgcctctg
     1381 gaacgaacaa tataaaaaca aaagaccact cttgtcgctc agctagtgtt ttatagcctg
     1441 tttctttcac aaattgagca aattcttgat tcgtaactgg agtatccgca atggaaaaat
     1501 cctttacact aacagcgact tgaggacctt caaaatcatc taaaaagccc tcttcagaat
     1561 ttgttcccat cataaatgtc ccacccttga tttttttcat tttcatgatt gactatcccc
     1621 cgttttcgtt agagttggcg ttattttaga aagttcaaca ggaactaact cttcatccac
     1681 aacaaaacct tcttctctat atctaagaaa gtctactaat tttttcttca tctgacgaac
     1741 aataggttgg tatttttcac ttggatacaa atcattcatt tcatgcggat cttttttcat
     1801 atcaaataac tgataatgat ttaaaacagg aaaccagata aatttccact ggtctgtcaa
     1861 gatatattga ctagaatctt ttcctaaagc atgttcacca tgaaattctg ttcgccaccc
     1921 ctcgtactgt ccaaataata aattcttaac actccgtcca tctagttcat ctgtagtagt
     1981 tcctcctgcc aaatccacga gtgaaggaaa aatatcttga attttcacta attgcttgat
     2041 tgttccccta ttaccagcta tcaatccagc cggatcgtaa ataaacgaag gaatgtggat
     2101 acttccctga taaggatatc cctttctaaa cagataatgt tcaccaagct gatctccatg
     2161 atccgaaaca aaccagataa tcgtatcttt atcatgacga aattctttta gggcagtcaa
     2221 aaagcgacta atttgatggt ctatatgagt aatcaatcca aaataagcag caaccattct
     2281 tctttgatca tcttccttta atttccctct taaagcataa atagacggaa tttgcttttc
     2341 taatacttcc caattcccga tatgcaaatc gagaaattga ggcaagcgtt ccatatacat
     2401 atcaaaatag tattttgggg gatttaatgg agcatgtggt ttttcaaaag acattttgag
     2461 aaaaaaagga accgttggat ctcttctttg taaaaatgaa atggactcac tcacaaccca
     2521 gtttgttgga tgtaacttct catctttatc ccaaggtcta gcttcccaag aattacaatc
     2581 cattccgtca tcaatcaaat caacatcata accaacttta ccctttaaaa aggctagata
     2641 gtcactagca taatcaaatt gacttccata agccttatca tactttctat caacatgtag
     2701 atacccatcg tgaagtaaga catgatcaaa cccaagtctc tgtctggaag gaaaaacatg
     2761 catcttacca atacactctg tttgataacc catatcttta aagacttttg gaagagtatt
     2821 agtaaaattc caaggcacct catcttgata accaactcgt ccacttttat cttggtctaa
     2881 gccagtcaat aaagctgccc tagcaggaac gcaagaagga actggagaat aggcattttc
     2941 aaaattataa cctacactag ccatcatatc taatgttgga gtgctaacta gcttatcctt
     3001 actattcaag gataaggcgt ctgctctcat ttgatctaca acaatcaaaa taatatttgg
     3061 ctgttttgtc tgaaccataa aatctccttt ctaatatggc aaaagaggca caagaagata
     3121 tctaccttta ctgcacccct ttctatatca atctctctat ataaaacaat aacattcttg
     3181 ttatgtttta tagaaaaatg aactaaaata tgactaaatc gattaggaaa ttcaaatcat
     3241 tttctagtac tgttttagaa gttacagtgt actattccaa cttcaataaa ctataaacct
     3301 ttgtctaata acaattttag tggagataag aaatcctaca cctaactcat cttacacgta
     3361 atctatttct attttatcac aaaaaacgca agtaagacca ttaactcaat tcagttttat
     3421 atgccatttt cacaaatggg aaataagtca agacactaat aatcaaacaa acaactgata
     3481 agatgatggc acgccaatca aatgctgtag agaagaaacc atataaaatt ggaggcatta
     3541 cccaagtaac gttttgtgta acaggtgaaa caagacccca gcttgttgcc cagtaagcta
     3601 ccgttgccat gaaaaccgga ctaagtacaa atggtataaa tagcaaagga ttcaagacaa
     3661 ctggtaaacc ataattgacc ggctcaccaa tattaaacag aactggtgct agaccaagtt
     3721 tagcaacttt tcgataatga ctgtttcttg aaaaaattaa aatagcaagt actaatccta
     3781 atcctccaaa ccagacaaac gccccaaaag acccacttgt ccatatataa ggaatcggtt
     3841 cacctttttg gaaagcatcc agattcgcta acatagcaac tccaaacagc ccttccatga
     3901 tgggagccaa tacatttcct ccatggagac caaaaaacca gaataactta ttcaaaaaga
     3961 tcatcagaat aactgcaaag aaactttgag acaaacctag taatggcgtt tgtaacacct
     4021 tgtaaaccca atcaatcaat aagtcattgc taagtaaatg gaaaacataa gtcaagatgg
     4081 ctactatata catcgccata aatcctggaa tgatagaagt gaacggctta gcaatcgcag
     4141 ggggaactga atctggtaac ttgattaccc agttcttttt cattacttta cagaaaataa
     4201 tagaggctaa aaatccaatc atcatggctg taaagtagcc tctggcatta atatggtttc
     4261 ctggaatcac attcccaata gttaccatca gatttttacc atcaaatgct agattatcaa
     4321 ttccttgtaa gatttgatct aatttcacat ctcctacatt tgccaaaggg aaactctttg
     4381 taactgtact tccaatcgaa atgacaaacg aagcaagtga taccaaacca gcagaaactg
     4441 tatcaacctt gtaaatctta gcgatattca ctcccaagca atagatgaac aacaaggaaa
     4501 caattggtat acttcccttg aataccaaat tattgatgtc aacaagccac tgaaaggttt
     4561 tcgtaatact ttctaggtga aattgttgtg gtaaatccac tagaaaagca tttaataaca
     4621 aagcaatgga acctgtcata ataacaggca tagtccccac aaatgaatca cgtaaagcaa
     4681 ctaaaaactt ctgattccca actttcattg caattggaga aagtttttct tgcattttat
     4741 ccaacattgt attcatacca aactcctaat ttttttcaaa tcgttcgtat acttctacca
     4801 cttctttcgc caagtcaaca aaagtcagac tcgtcattaa atgatcttgc gcgtgtacca
     4861 tcaagaggct aattgatgtt ttttccccct gtgcctctct tgtcaacatt tctgtttgag
     4921 ccttatgcgc ctgtaataag gcagcattcg catcagctaa tcttcgattg gctttagaga
     4981 aatccccttt ttttgctgcc tgaatagcct ccatagcatt acttttggct tccccaccat
     5041 acataattag ccccattaca gattctaaat tactttcatc cataacattc tcctcaatct
     5101 tagtctaata aactttcagc taaatctaaa actttagaac cattcatcat tccgtaatct
     5161 gtcatcggaa taaccgccac aggaatctgt ctatctttta gtttttcttg aaagtcccct
     5221 agtaaatagc gaacttgagg acctaaaagc aacacattta cttcttttgt tgctacaatt
     5281 tcttctgctt caggagctgg aactgcaaaa atttctgcat ccaacccctt atcttctgct
     5341 gccttttgca tctttgtcac tagcagactt gtactcatac ctgctgcaca tgctaacata
     5401 attgttactt tagccatagc ttactccttt atcacctatt tactgaccta gccaagcgag
     5461 atactgtatg tctcactcct ctaattgcct tgctcaatgc ataaatatta tcgactgttg
     5521 ccagtccccc atatcctgcg tcacctatat gttgaatatc aactccacaa attttatttc
     5581 taagtgcaat ttccttgata gtatctgtat cagatgtttc ttggctagta ccaatagcac
     5641 tcaatacaag accaccctta ctatgaacga gatcaacgac ttcacgcaac tcttggtcat
     5701 gaaaggctgg aacggttcca actgctggaa caagtatcac atccgcacct gcttccaaca
     5761 attgctctgc gacagaaagc tctgccacag gctcattcac tcctgccccg tgcatcttac
     5821 ctgcaataat caaaccagaa aagttttcct tagcagtttg aacagcctta atgatttctc
     5881 gattgctaac tcctgttcca ggatttccag tcaaacagac aaagtcaaaa cctaactcct
     5941 ctattcgatt caatgtttca acactagcaa cacgacctgc aacaatttcc tgtgtttcct
     6001 ctagcatctt tgcagatggg tcaatcggtt ccaaatttac accaattgga caagcaacaa
     6061 gctggtgtaa gcgatgaata acatcatcac ctgaactatc caaagcataa attttaggct
     6121 caaaaacatc aacacaattc aataaaatca tatcagctcc aaaagctcta gcaatttcag
     6181 aattagttat atccccaaca aatgtctcac gagtaactac attttcagat agaacaactc
     6241 taccttcact tgctaaaata ctttgtttta attcttcagc attcatctgt aatatctcag
     6301 atggatttgc actaattaaa cgtttcattc tcaatcctcc aataacttaa atcgtttttc
     6361 aatagctatt acaaatggta aataaagtaa gatatccaaa acaatcaata caatttgtag
     6421 taatgaacca gaaatacttc ctgtagcaag taaaccactt ataacaggtg gcatagtcca
     6481 acctggatct gtataagtta gcggaaccaa acctgatgcc attgctcccc acgctactag
     6541 taagttaaac attggagcta agataaatgg aactagtaac aaaatgttca aaacaatagg
     6601 aacgccaaac attgctggtt catttatatt aaataatcca ggtataacag ttataggtgc
     6661 caaagttttt agttgtttac tagctttctt cttatgtgct aaatatccta acgcaagaac
     6721 taaacctatg gttgcaccac cgccacctat gaatacaaaa ttatccataa atacgctagt
     6781 aaaaatattt ggaagagttt ctccagtttg ataagctact ttatttgcat ctagattagc
     6841 taaccataac ggtttcataa ctgcattaac aacatttcct ccgtgtaatc ctacaaacca
     6901 aaaactacta ttaaggaaaa ttaagataag aagaccaata acattatttc ctaaaagtcc
     6961 aagtggacct cccaaagcta cttgagcaat ttcatgaaga ttaggtaaac ttaatttatc
     7021 taaagttgca taaacaatca accaaccaac aatagtcact gcaccaggaa taatggcact
     7081 aaagctttta gatactgctg gtggaacacc atccggcatt tttatctgta tattatgatt
     7141 tataaaccat tggtagatat agccattaat caatcctaaa atcatagcaa caaataaacc
     7201 ttttgatgcc atgaaagcgg taggcattcc tgctccagcc tctcctctaa tgaaaggcgt
     7261 aactgtaata aaagatgata atgacacaat accagcagga ataccatcaa ctttgtattg
     7321 tctagccata aagtaagcga taccaaaact agctacaaga ccaagtaatc caaaactact
     7381 atcaacaccc ttccataaat agtcagcaac accaatatca cccagatatt tttcccatcc
     7441 tggaatagga aaacttgcaa taaccattag taatgaacct atcaacaata aaggtatagt
     7501 tagagtaata ccgtctcgaa tagaaaccaa cgctttatta ttacccaatc tagccgctac
     7561 tggaagtaac ttttcttgta ataatttttc cataaccttt tcctcttaaa tatattttat
     7621 tatcaaaagt tatcaattat ctttattttt tgacgtcaag ttgttatttg attatc
//
LOCUS       DBEJKC010000074         7608 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.074, whole genome shotgun sequence.
ACCESSION   DBEJKC010000074 DBEJKC010000000
VERSION     DBEJKC010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7608
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.074"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            422..2527
                     /locus_tag="ACL3G6_001878"
     CDS             422..2527
                     /locus_tag="ACL3G6_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR0546354.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRTTGQLPGNAETDVQMSQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFNILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGNFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(2823..3305)
                     /locus_tag="ACL3G6_001879"
     CDS             complement(2823..3305)
                     /locus_tag="ACL3G6_001879"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HGR0546355.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(3400..4884)
                     /locus_tag="ACL3G6_001880"
     CDS             complement(3400..4884)
                     /locus_tag="ACL3G6_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HGR0546356.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPGGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMSERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            5037..6644
                     /locus_tag="ACL3G6_001881"
     CDS             5037..6644
                     /locus_tag="ACL3G6_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HGR0546357.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKELLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            6809..6976
                     /locus_tag="ACL3G6_001882"
     CDS             6809..6976
                     /locus_tag="ACL3G6_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HGR0546358.1"
                     /translation="MKKRILSAGLTFTSDLLLAACGQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(6969..7608)
                     /locus_tag="ACL3G6_001883"
                     /pseudo
     CDS             complement(6969..7608)
                     /locus_tag="ACL3G6_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         2288 a         1428 c         1719 g         2173 t
ORIGIN      
        1 tttagaaatc gatttgactg tcctgaacga tttatcctgt tcttatttca ttttactata
       61 cagtttcgag gttgtagata aggcgaagct gatgtggttt gaagagattt tcgaagagat
      121 aaaaaatatt ggtcaattaa agtcaaaatc cttgaccttt tctgactaat gtagtatatt
      181 atgaacgtaa ggtaaatgaa agccttacta gaacacttat ttaaagtaaa atagaaagag
      241 gtggggtcta tgtttaatct agaaatcttc agaagtaaag atggtctact cctgcttgaa
      301 aaagaaaaac cagaaatagt acgtagggta gcggtttagc tagtctaaat tttttaaaac
      361 aaaggtcaaa gatagtcaat atcagtaatc ataactaagt aaacaaaaag aggtaaagaa
      421 tatgaataac aactttaata attttaataa catggatgat ttatttaacc aattgatggg
      481 tggtatgcga ggatacagtt ctgaaaatcg ccgttactta attaatgggc gcgaagtcac
      541 acctgaggaa tttgctcact atcgtacgac tggtcaatta ccaggaaatg cagaaactga
      601 tgtgcaaatg tcacaacagg catcaggtat gaaacaagac ggtgtccttg caaaactagg
      661 tcgaaacttg acagcagaag cgcgtgaggg taagttggat cctgttatcg gacgaaacaa
      721 ggaaattcaa gaaacatctg aaatcctctc acgccgcacc aagaacaatc ctgttttggt
      781 cggagatgca ggtgttggta agacagcagt tgtcgaaggt ctagcgcaag ccattgtgaa
      841 cggagatgtt cctgctgcta tcaagaacaa ggaaattatt tctattgata tctcaggtct
      901 tgaggctggt actcaatacc gtggtagctt tgaagaaaat gtccaaaact tagtcaatga
      961 agtgaaagaa gcagggaata ttatcctctt ctttgatgaa attcaccaaa ttcttggtgc
     1021 tggtagcact ggtggagaca gtggttctaa aggacttgcg gatattctca agccagctct
     1081 ctctcgtgga gaattgacag tgattggggc aacaactcaa gacgaatacc gtaacaccat
     1141 cttgaagaat gctgctcttg ctcgtcgttt caacgaagtg aaggtcaatg ctccttcagc
     1201 agagaatact tttaacattc ttcaaggcat tcgtgacctc tatcaacaac atcacaatgt
     1261 catcttgcca gacgaagtct tgaaagcagc ggtggattat tctgttcaat acattcctca
     1321 acgtagcttg ccagataagg ctattgacct tgtcgatgta acagctgctc acttggcggc
     1381 tcaacatcca gtaacagatg tgcatgctgt tgaacgagaa atcgaaacgg aaaaagacaa
     1441 gcaagaaaaa gcagttgaag cagaagattt tgaagcagct ctaaactata aaacacgcat
     1501 tgcagaattg gaaaagaaaa tcgaaaacca cacagaagat atgaaagtga ctgcaagtgt
     1561 caacgatgtg gctgaatctg tggaacgaat gacaggtatc ccagtatcgc aaatgggagc
     1621 ttcagatatc gaacgtttga aagatatggc tcatcgcttg caagacaagg tgattggtca
     1681 agataaggcc gtagaagttg tagctcgtgc tatccgtcgt aaccgtgctg gttttgatga
     1741 aggaaatcgc ccaatcggca acttcctctt tgtagggtct actggggttg gtaagacgga
     1801 gcttgctaag caattggcac tcgatatgtt tggaacccag gatgcgatta tccgtttgga
     1861 tatgtctgaa tacagtgacc gcacagctgt ttctaagcta attggtacaa cagcaggcta
     1921 tgtgggttat gatgacaata gcaatacctt aacagaacgt gttcgtcgca atccatactc
     1981 tatcattctc ttggatgaaa ttgaaaaggc tgaccctcaa gttattaccc ttctcctcca
     2041 agttctagat gatggtcgtt tgacagatgg tcaaggaaat acagtaaact tcaagaacac
     2101 tgtcattatt gcgacctcaa atgctggatt tggctatgaa gccaacttga cagaagatgc
     2161 ggataaacca gaattgatgg accgtttgaa acccttcttc cgtccagaat tcctcaaccg
     2221 ctttaatgca gtcatcgagt tctcacactt gactaaggaa gacctttcta agattgtaga
     2281 tttgatgttg gctgaagtta accaaacctt ggctaagaaa gacattgact tggtagtcag
     2341 tcaagcggct aaagattata tcacagaaga aggttacgac gaagtcatgg gggttcgtcc
     2401 tctccgtcga gtggttgaac aagaaattcg tgataaggtg acagacttcc acttagatca
     2461 tttagatgct aaacatctgg aagcagatat ggaagatggc gttttggtta ttcgtgagaa
     2521 agcctaagat agaattttga ggataaaaaa gaaggagcca gctgaaaaaa actggttcct
     2581 tttgaggtac gacgggcatg tcgtacagta gaagtgtact attctagttt caatccacta
     2641 tagtagctca gaagtcggta cttaaacgtg ctatatcaaa accagtcctt gaaaaacgtg
     2701 gattggtttc gtgtttggat tattaccttg aacgacatgc gttaaaagtt agttgaaccg
     2761 ccgtatgccg aacggcacgt acggtggtgt gagaggggct agagattatc ccctactcga
     2821 ttttaaatca catgacgttc aaaggcatca tctgaaatcc cttgttccaa gatgagtttt
     2881 gcccattctt tagcagagaa gaggctgtgg tccttgtagt ttccgcaaga ttcgatggtt
     2941 gtccctggga catcttccca agtagtagtt tcagcgattt ccttgagcga atccttgata
     3001 acagctgcga ttttagcact ggtgtgacgt ccccacataa tcatgtggaa gcctgtgcgg
     3061 caaccaaatg gtgaacagtc aatcatgccg tcaatgcggg tacggatgag tttggctaag
     3121 aggtgctcga tagtgtgaag gccggcagta gggatagagt cttcgtttgg ttgcaccaag
     3181 cgaatatcat aattggagat gatgtctcct tttggtcctg tttcttcccc aatcaagcga
     3241 acatagggtg ctttgacaat ggtgtggtca agttcaaaac tttcgacaat aacttctttt
     3301 gacatggtaa atcctttcag ttttcttctc tcattatatc ataaaggttg ttcctgagac
     3361 agagagaaaa cctctccgag gctagagagg ttgaaatctt tacttacgat ataagcggtc
     3421 gtattggtag tatgggtcaa aggttacgtt gatacccagt ttacgaagga cattcttgtc
     3481 ttcatcagtc aagatgatgg ttgagtgggc ttcgcttcct ttgaggttgc ctagttcttc
     3541 catagcgcgg gcagcatcag gattttctgt agctgtgata gcaagtgcaa tcaggatttc
     3601 atttgaatga aggcgtggat tgcggctacc gagatgatcg attttaagac cttggattgg
     3661 cttaacaact tcaggttcga ttagttttac ttctttagcg atgtcagctg attttttgat
     3721 ggcgttgatc aaggcagcgg ctgtaggacc aaagagttct gagttcttac cagtgacgat
     3781 ttccccattt ggcaattcaa aggctagggc tggtccacca gtttcttctg ctttttggcg
     3841 cgcaacgaca gcaaccttac ggtctgcagg tgtgataccg aggtcgttca tgagcaactc
     3901 aattttcttg acggcagctt cgccaacttt ttcagctttg aagtcaagaa ctgtttgata
     3961 gtaacggcgg atgatttctt gtttagaagc ttcgacagcg gcctcgtcat ctgtaatagc
     4021 gaaaccaacc atgttgacac ccatatctgt cggtgaagcg tatggtgatt ttccgagaat
     4081 acgttccgac atgcgtttga gcactgggaa gatttcgata tcacggttgt agttgacagt
     4141 ggtttctcca taggtttgaa gatggaaggg gtcaatcatg ttgacatcat caaggtcagc
     4201 tgtggcagct tcataagcca agttaactgg atgatgaagg ggaagattcc aaacagggaa
     4261 ggtttcaaat ttagcgtagc cagatttgat gccattgatt tggtcgtggt acatattgga
     4321 catacacgtt gccaattttc cagaaccggg tccaggagcg gttacgacaa tcaagttgcg
     4381 actggttttg atgtagtcgt ttttgcccat gcctcctggg gaaatgatgt gatccatatc
     4441 cgtaggatat cctttgattg gataatgaag ataagaatca attccgtttt tctcaagttg
     4501 gttgcggaag gcatctgcag cgggttggcc agcgtattgt gtaatgacaa cggaaccaac
     4561 aaaaatccct aattcattga atttgtcaat caaacgaaga acttcttggt cataagaaat
     4621 gcctaagtcg ccacgtgctt tggaatgttc aatgttgcta gcattaatgg caatcacaac
     4681 ctcaacctgc tctttcaatt cttgcaagag cttgattttg ttgtcaggtt cataaccagg
     4741 aaggacacga gcagcgtgga aatcttctaa cattttaccg ccaaactcta agtagagctt
     4801 gccgtcaaat tggttaatgc gctccaaaat atggtcgcgt tgtaaattca aatactgttc
     4861 agaactaaaa gcttgttttt tcattttttt acctctggac tctattataa taaaaaattg
     4921 gaagttagga aactacggag ctaaaaaaga aattaaaaag attaagcaaa cgcttgcaca
     4981 aaattttaaa aagtgctatc atagactata gattattaaa ataatgaggt aaacagatgc
     5041 aagaaaaatg gtggcataat gccgtagtct atcaagtcta tccaaagagt tttatggata
     5101 gtaatggaga tggagttggt gatttgccag gtattaccag taagttggac tatctagcta
     5161 agttaggaat cacagcgatt tggctttctc ccgtttatga cagccctatg gatgataatg
     5221 gctacgatat tgctgattat caagcgattg cggctatttt tggaaccatg gaggacatgg
     5281 atcagctgat tgcagaagct aagaagcgtg atatccgtat catcatggac ttggtggtca
     5341 atcatacctc ggatgagcat gcttggtttg tcgaagcctg tgaaaatact gacagccctg
     5401 agcgagacta ctatatctgg cgcgatgaac ccaatgacct agattctatc tttagtgggt
     5461 ctgcttggga atacgatgaa aagtcaggtc aatactatct ccactttttc agcaagaaac
     5521 agccggatct caactgggaa aatgaaaaac ttcgccagaa aatttatgag atgatgaact
     5581 tctggattga taaaggtatt ggtggtttcc gtatggatgt tattgacatg attggcaaaa
     5641 ttcctgacga gaaggtagtc aataatggtc ctatgctcca tccctatctc aaggaaatga
     5701 atcaggcgac ctttggagat aaggagctct tgacagtagg ggagacttgg ggagcaacgc
     5761 cagagattgc caagctctac tctgatccaa aggggcaaga attgtctatg gtcttccagt
     5821 ttgaacatat cggtcttcag tatcaggaag gtcagcctaa atggcactat caaaaagagc
     5881 tgaatatcgc taagttaaaa gaaatcttca acaaatggca gacagagtta ggagttgagg
     5941 acggctggaa ttccctcttc tggaacaacc atgacctccc tcgtattgtc tcaatctggg
     6001 gaaatgacca agaataccgc gaaaaatctg ccaaagcctt tgcaatctta cttcatctca
     6061 tgagaggaac tccttatatc taccaaggtg aggagattgg gatgaccaac tatccgtttg
     6121 aaacactgga tcaagtagaa gatattgaat ccctcaacta tgcgcgtgag gctcttgaaa
     6181 aaggtgttcc gattgaagaa atcatggaca gtatccgtgt tattggacgt gacaatgccc
     6241 gtacccctat gcaatgggac gagagcaaaa acgctggttt ctcaacaggt caaccttggt
     6301 tggcggttaa tccaaattac gagatgatca acgtccaaga agcgctggca aatccagatt
     6361 ctattttcta tacctatcag aaactggtcc aaattcgcaa ggagaatagc tggctaattc
     6421 gagctgactt tgaattgctt gatacggctg ataaggtctt tgcttatata cgtaaggatg
     6481 gcgaccgtcg cttcctagtt gtggctaact tgtctaatga agagcaagac ttgacagtag
     6541 aaggaaaagt caaatctgtc ttgattgaaa acaccctagc tcaagaagtc tttgaaaaac
     6601 aaatcttagt tccatgggat gctttctgtg tggaattact ataaatattt tttgcagaaa
     6661 aatttaaaat tgaaatcgta taaaaacaag ggaggactgt ataaaaggca gaaatccttt
     6721 gttttttata accaaggttt ataaaccttc attctcgaaa ttcaattaac tttacaaatt
     6781 cccactatta aggagaaaga agacgaacat aaagaagcgt atccttagtg caggcctgac
     6841 ttttacatct gatttgcttt tagctgcttg cggccaatca ggttcagata caaaaactta
     6901 ctcatcaacc tttagtggaa atccaactac atttaactat ctattagact attacgctga
     6961 taatatagtc aattgaaaca agaacaggac aaaagagcct cataaaaggt attgcaactt
     7021 ggtaatacct ttttgaggtg ctttttgata tgagcccatg ttttctcaat aggattgtac
     7081 tcaggcgagt agggaggaag aggtaaaagt ttatgcccaa actcttcaca caagagttct
     7141 agcttcccca ttctatggaa tcttgcatta tccataataa taaccgatgg tgtggttaat
     7201 gttggtaaga gaaacttctg aaaccaagct tcaaaaaagt cgctcgtcat catctcttcg
     7261 taagtcattg gagcgattaa ctcaccattc atttgttaga cctgcaacca aagaaatcct
     7321 ctgatatctt cttccagata ctttacctct tcttaactga ccttttaatg agcgaccata
     7381 ttctcgatga aaataagtat cgaatcctgt ttcatcaatc taaacaggtg ctaggtgctt
     7441 taaactatta aaattcttaa gaaataaggc tactttttct gggtcttgtt catagtaggt
     7501 gtggttcttt ttttcgagtg tagcccatag ctttgagcgc atagtggatg gtagttggat
     7561 gacaggcaaa ttcagaagct atttcagtca aataagcgtc tggattat
//
LOCUS       DBEJKC010000075         7068 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.075, whole genome shotgun sequence.
ACCESSION   DBEJKC010000075 DBEJKC010000000
VERSION     DBEJKC010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7068
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.075"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            225..6659
                     /locus_tag="ACL3G6_001884"
     CDS             225..6659
                     /locus_tag="ACL3G6_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGR0546359.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     VVDKETENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEAKIKE
                     ENSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKGLSNLKNTKVLYT
                     YDRIFNGSAIETTPDNLDKIKQIEGISSIERAQKVQPMMNHARKEIGVEEAIDYLKSI
                     NAPFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDK
                     IPHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNA
                     QIFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRA
                     LRKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQ
                     TVEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLD
                     LRGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEG
                     TKSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNV
                     GDEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVI
                     NGKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIAL
                     QNTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYG
                     SISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDG
                     KQIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFES
                     VEEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDG
                     KPKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSS
                     GSKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVI
                     SREHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPAT
                     KIRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLI
                     TKDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTY
                     AGEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFADQADEK
                     GMISYYLVDPDKDASKYEKLGEISEDKLKNAKSPEENTNNNQAKDEDSKPDEKSSVEG
                     EASLEINKTISTIREFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKRNIIA
                     YDDGSALQYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIE
                     IKATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKE
                     TKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
BASE COUNT         2794 a          953 c         1356 g         1965 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttttgactt
       61 aaattttttt aaatgatata ctgtttttat agagagataa caattatata taaatgtact
      121 actctatttc ctagataata cttagtaaaa ctttttataa caaaggctag caaagttaaa
      181 gtttattatc tattggaagt taaataaata tgtaaggaat taaaatgaaa aaaagcacag
      241 tattgtcatt aactacagct gcagttattt tagcagccta tgcccctaat gaggtagtct
      301 tagcagacac atctagctct gaagatgctt taagcatctc tgataaagaa aaagtagtag
      361 tagataagga aacagaaaat aaagagaaac ataaagatat tcataatgct atagaaactt
      421 caaaggatac tgaagaaaag aaaacaacaa ttattgagga aaaagaagtt gttagtaaaa
      481 atcctgtaat agacactaaa actagcaatg aagaagcaaa aatcaaagaa gaaaattcca
      541 atcaatccca aggagatcat acggactcat ttgtgaataa aaacacagaa aatcccaaaa
      601 aagaagataa agttgtctat attgctgaat ttaaagataa agaatctgga gaaaaagcaa
      661 tcaagggact atcaaatctt aagaatacaa aagttttata tacttatgat agaattttta
      721 acggtagtgc catagaaaca actccagata acttggacaa aattaaacaa atagaaggta
      781 tttcatcgat tgaaagggca caaaaagtcc aacccatgat gaatcatgcc agaaaggaaa
      841 ttggagttga ggaagctatt gattacctaa agtctatcaa tgctccgttt gggaaaaatt
      901 ttgatggtag aggtatggtc atttcaaata tcgatactgg aacagattat agacataagg
      961 ctatgagaat cgatgatgat gccaaagcct caatgagatt taaaaaagaa gacttaaaag
     1021 gaactgataa aaattattgg ttgagtgata aaatccctca tgcgttcaat tattataatg
     1081 gtggcaaaat cactgtagaa aaatatgatg atggaaggga ttattttgac ccacatggga
     1141 tgcatattgc agggattctt gctggaaatg atactgaaca agatatcaaa aactttaacg
     1201 gcatagatgg aattgcacct aatgcacaaa ttttctctta caaaatgtat tctgacgcag
     1261 gatctgggtt tgcgggtgat gaaacaatgt ttcatgctat tgaagattct atcaaacaca
     1321 acgttgatgt tgtttcggta tcatctggtt ttacaggaac aggtcttgta ggtgagaaat
     1381 attggcaagc tattcgggca ttaagaaaag caggcattcc aatggttgtc gctacgggta
     1441 actatgcgac ttctgcttca agttcttcat gggatttagt agcaaataat catctgaaaa
     1501 tgaccgacac tggaaatgta acacgaactg cagcacatga ggatgcgata gcggtcgctt
     1561 ctgctaaaaa tcaaacagtt gagtttgata aagttaacat aggtggagaa agttttaaat
     1621 acagaaatat aggggccttt ttcgataaga ataaaatcac aacaaatgaa gatggaacaa
     1681 aagctcctag taaattaaaa tttgtatata taggcaaggg gcaagaccaa gatttgatag
     1741 gtttggatct taggggcaaa attgcagtaa tggatagaat ttatacaaag gatttaaaaa
     1801 atgcttttaa aaaagctatg gataagggtg cacgcgccat tatggttgta aatactgtaa
     1861 attactacaa tagagataat tggacagagc ttccagctat gggatatgaa gcggatgaag
     1921 gtactaaaag tcaagtgttt tcaatttcag gagatgatgg tgtaaagcta tggaacatga
     1981 ttaatcctga taaaaaaact gaagtcaaaa gaaataataa agaagatttt aaagataaat
     2041 tggagcaata ctatccaatt gatatggaaa gttttaattc caacaaaccg aatgtaggtg
     2101 acgaaaaaga gattgacttt aagtttgcac ctgacacaga caaagaactc tataaagaag
     2161 atatcatcgt tccagcagga tccacatctt gggggccaag aatagattta cttttaaaac
     2221 ccgatgtttc agcacctggt aaaaatatta aatctacgct taatgttatt aatggcaaat
     2281 caacttatgg ctatatgtca ggaactagta tggcgactcc aatcgtggca gcttctactg
     2341 ttttgattag accgaaatta aaggaaatgc ttgaaagacc tgtattgaaa aatcttaagg
     2401 gagatgacaa aatagatctt acaagtctta caaaaattgc cctacaaaat actgctcgac
     2461 ctatgatgga tgcaacttct tggaaagaaa aaagtcaata ctttgcatca cctagacaac
     2521 agggagcagg cctaattaat gtggccaatg ctttgagaaa tgaagttgta gcaactttca
     2581 aaaacactga ttctaaaggt ttggtaaact catatggttc catttctctt aaagaaataa
     2641 aaggtgataa aaaatacttt acaatcaagc ttcacaatac atcaaacaga cctttgactt
     2701 ttaaagtttc agcatcagcg ataactacag attctctaac tgacagatta aaacttgatg
     2761 aaacatataa agatgaaaaa tctccagatg gtaagcaaat tgttccagaa attcacccag
     2821 aaaaagtcaa aggagcaaat atcacatttg agcatgatac tttcactata ggcgcaaatt
     2881 ctagctttga tttgaatgcg gttataaatg ttggagaggc caaaaacaaa aataaatttg
     2941 tagaatcatt tattcatttt gagtcagtgg aagaaatgga agctctaaac tccaacggga
     3001 agaaaataaa cttccaacct tctttgtcga tgcctctaat gggatttgct gggaattgga
     3061 accacgaacc aatccttgat aaatgggctt gggaagaagg gtcaagatca aaaacactgg
     3121 gaggttatga tgatgatggt aaaccgaaaa ttccaggaac cttaaataag ggaattggtg
     3181 gagaacatgg tatagataaa tttaatccag caggagttat acaaaataga aaagataaaa
     3241 atacaacatc cctggatcaa aatccagaat tatttgcttt caataaccaa gggatcaacg
     3301 ctccatcatc aagtggttct aagattgcta acatttatcc tttagattca aatggaaatc
     3361 ctcaagatgc tcaacttgaa agaggattaa caccttctcc acttgtatta agaagtgcag
     3421 aagaaggatt gatttcaata gtaaatacaa ataaagaggg agaaaatcaa agagacttaa
     3481 aagtcatttc gagagaacac tttattagag gaattttaaa ttctaaaagc aatgatgcaa
     3541 agggaatcaa atcatctaaa ctaaaagttt ggggtgactt gaagtgggat ggactcatct
     3601 ataatcctag aggtagagaa gaaaatgcac cagaaagtaa ggataatcaa gatcctgcta
     3661 ctaagataag aggtcaattt gaaccgattg cggaaggtca atatttctat aaatttaaat
     3721 atagattaac taaagattac ccatggcagg tttcctatat tcctgtaaaa attgataaca
     3781 ccgcccctaa gattgtttcg gttgattttt caaatcctga aaaaattaag ttgattacaa
     3841 aggatactta tcataaggta aaagatcagt ataagaatga aacgctattt gcgagagatc
     3901 aaaaagaaca tcctgaaaaa tttgacgaga ttgcgaacga agtttggtat gctggcgccg
     3961 ctcttgttaa tgaagatgga gaggttgaaa aaaatcttga agtaacttac gcaggtgagg
     4021 gtcaaggaag aaatagaaaa cttgacaaag acggaaatac catttatgaa attaaaggtg
     4081 caggagattt aagaggaaaa atcattgaag tcattgcatt agatggttct agcaatttca
     4141 caaagattca tagaattaaa tttgctgatc aggctgatga aaaggggatg atttcttatt
     4201 acctagtaga tcctgacaaa gatgcttcta aatatgaaaa acttggtgaa atttctgaag
     4261 ataaactcaa aaatgcaaag agcccagagg aaaataccaa taataatcaa gctaaggatg
     4321 aagattcaaa accagatgaa aaaagttcag ttgagggaga agctagcctt gaaataaata
     4381 aaactatttc aacaattaga gagtttgaaa ataaagacct aaagaaactc attaaaaaga
     4441 aatttagaga agttgatgat tttacaagtg aaactggtaa gagaatagag gaatacgatt
     4501 ataaatacga tgataagaga aatattattg cttatgacga tggtagtgcc ttacaatatg
     4561 aaactgaaaa atttgacgaa ataaaatcaa aaatttatgg tgttctaagc ccatctaaag
     4621 atggacactt tgaaattctt ggaaagataa gcaatgtttc taaaaatgcc aaggtatatt
     4681 atggaaatag ctataaatcg atagaaatca aagcgactaa gtatgattca cattcaaaaa
     4741 cgatgatatt tgatttatac gctaatatta atgatattgt agatggatta gcttttgctg
     4801 gagatatgag attatttgtt aaagatgaca atcaaataaa agctgaaact aagattagaa
     4861 tgcctgaaaa aaataaggaa actaaagcag aatatcccta tgtatcaagt tatgggaatg
     4921 taatcgaatt aggagaagga gatctttcaa agaacaaacc agacaattta actaaaatgg
     4981 aatctggtaa aatctattct gattcagaaa aacaacaata tctgttaaag gataacatca
     5041 ttctaagaaa aggctatgca ctaaaagtga ctacctataa tcctggaaaa acggatatgt
     5101 tagaaggaaa tggagtctat agcaaggaag atatagcaaa aatacaaaag gccaatccta
     5161 atctaagagt cctttcagaa acaacaattt atgctgatag tagaaatgtt gaagatggaa
     5221 gaagtaccca agctgtatta atgtcggctt tggacggctt taacattata aggtatcaag
     5281 tgtttacatt taaaatgaac gataaagggg aagctatcga taaagacgga aatcttgtga
     5341 cagattcttc taaacttgta ttatttggta aggatgataa agaatacact ggagaggata
     5401 agtccaatgt agaagctata aaagaagatg gctccatgtt atttattgat accaaaccag
     5461 taaacctttc aatggataag aactacttta atccatctaa atctaataaa atttatgtac
     5521 gaaatccaga attttattta agaggtaaga tttctgataa gggtggtttt aactgggaat
     5581 tgagagttaa tgaatcggtt gtagataatt atttaatcta cggagattta cacattgata
     5641 acactagaga ttttaatatt aagctgaatg ttaaagacgg tgacatcatg gactggggaa
     5701 tgaaagacta taaagcaaac ggatttccag ataaggtaac agatatggat ggaaatgttt
     5761 atcttcaaac tggctatagc gatttgaatg ctaaagcagt tggagtccac tatcagtttt
     5821 tatatgataa tgttaaacct gaagtaaaca ttgatcctaa gggaaatact agtatcgaat
     5881 atgctgatgg aaaatctgta gtctttaaca tcaatgataa aagaaataat ggattcgatg
     5941 gtgagattca agaacaacat atttatgtaa atggaaaaga atatacatca tttgatgata
     6001 ttaaacaaat aacagacaag acactaaaca ttaagattgt tgtaaaagat tttgcaagaa
     6061 atacaaccgt aaaagaattc attttaaata aagatacggg agaggtaagt gaattaaaac
     6121 ctcatagggt aactgtgacc attcaaaatg gaaaagaaat gagttcaacg atagtgtcgg
     6181 aagaagattt tattttacct gtttataagg gtgaattaga aaaaggatac caatttgatg
     6241 gttgggaaat ttctggtttc gaaggtaaaa aagacgctgg ctatgttatt aatctatcaa
     6301 aagatacctt tataaaacct gtattcaaga aaatagagga gaaaaaggag gaagagaata
     6361 aacctacttt tgatgtatcg aaaaagaaag ataacccaca agtaaatcat agtcaattaa
     6421 atgaaagtca cagaaaagag gatttacaaa gagaagatca ttcacaaaaa tctgattcaa
     6481 ctaaggatgt tacagctaca gttcttgata aaaacaatat cagtagtaaa tcaactacta
     6541 acaatcctaa taagttgcca aaaactggaa cagcaagcgg agcccagaca ctattagctg
     6601 ccggaataat gtttatagta ggaatttttc ttggattgaa gaaaaaaaat caagattaag
     6661 acaaaagcta tagaaaaaaa tggtttatgt actgagatta gatagtgagg tgatgacata
     6721 gttttgtgaa aacagccatt tataactcaa ttatttagtt tacttcacta ttgatactat
     6781 ttggagttat taatggactt agtttagata actaatgaat tgattgaaag ggttagtatt
     6841 gacaatattg gtcatattga ttagaaaata gagtctatca aaatttaaag gctaatagag
     6901 gtgatgagac aatttcaagg aattaagtag cgtttggttg cttaattcct ttttatttgg
     6961 aaggaagttt ttcgtaaccg cccaataacg aagtctattg gacggttacg atatgatcac
     7021 tgacttcgtc agtcttatct acaacctcaa aactgtgttt tgagcaac
//
LOCUS       DBEJKC010000076         6781 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.076, whole genome shotgun sequence.
ACCESSION   DBEJKC010000076 DBEJKC010000000
VERSION     DBEJKC010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6781
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.076"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..372
                     /locus_tag="ACL3G6_001885"
     CDS             <1..372
                     /locus_tag="ACL3G6_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HGR0546360.1"
                     /translation="KVSGRRYQRISLVAGLTNGELIAPMTYEETMTSDFFEAWFQNFL
                     LPTLTTPSVIIMDNVRFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKKHL
                     KKVLPSCNTFYEALLSCSCFN"
     gene            433..1395
                     /locus_tag="ACL3G6_001886"
     CDS             433..1395
                     /locus_tag="ACL3G6_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0546361.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSSAQVVSLYEDTSISVSSNETDKV
                     LAGSLYTDTNEQGLMIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAEASKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1572..2579
                     /gene="gap"
                     /locus_tag="ACL3G6_001887"
     CDS             1572..2579
                     /gene="gap"
                     /locus_tag="ACL3G6_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGR0546362.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2647..3522)
                     /locus_tag="ACL3G6_001888"
     CDS             complement(2647..3522)
                     /locus_tag="ACL3G6_001888"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR0546363.1"
                     /translation="MQFTFTLPASLPQMTVKQLLEEQLLIPRKIRHFLRIKKHILINQ
                     EEVRWNEIVNPGDVCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTH
                     GNQPNEIALLNHVSTYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISR
                     EYWALVDGNINRKELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLA
                     HCKLKTGRTHQIRVHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTF
                     TTLSNTFEKELKKNG"
     gene            3609..5804
                     /gene="pbp2a"
                     /locus_tag="ACL3G6_001889"
     CDS             3609..5804
                     /gene="pbp2a"
                     /locus_tag="ACL3G6_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP2A"
                     /protein_id="HGR0546364.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5857..6009
                     /gene="rpmG"
                     /locus_tag="ACL3G6_001890"
     CDS             5857..6009
                     /gene="rpmG"
                     /locus_tag="ACL3G6_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR0546365.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6019..6195
                     /gene="secE"
                     /locus_tag="ACL3G6_001891"
     CDS             6019..6195
                     /gene="secE"
                     /locus_tag="ACL3G6_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HGR0546366.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6250..>6781
                     /gene="nusG"
                     /locus_tag="ACL3G6_001892"
     CDS             6250..>6781
                     /gene="nusG"
                     /locus_tag="ACL3G6_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HGR0546367.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT         2102 a         1192 c         1469 g         2018 t
ORIGIN      
        1 aaagtatctg gaagaagata tcagaggatt tctttggttg caggtctaac aaatggtgaa
       61 ttaatcgctc caatgactta cgaagagacg atgacgagcg acttttttga agcttggttt
      121 cagaattttc tcttaccaac attaaccaca ccatcggtta ttattatgga taatgtaaga
      181 ttccatagaa tggggaagct agaactttta tgcgaagagt ttgggcataa actgttacct
      241 cttcctccct actcgcctga gtacaatcct attgagaaaa catgggctca tatcaaaaag
      301 cacctcaaaa aggtattacc aagttgcaat accttttacg aggctctttt gtcttgttct
      361 tgtttcaatt gactatagtt cacggataca gttgggaaag aagctattaa ttatttggag
      421 agtccttttg ggatgaacat gtcaaatatt actatagatg ggcaagaaat ggatctgagt
      481 caaacgatgc cttcttctgc tcaagtagtg agtctttatg aggatacaag catctctgtt
      541 agtagtaatg agacggacaa agtgttggct ggatccctct atactgatac aaatgaacag
      601 ggattaatga ttccaagcag tttactaaaa aattggaatg aacagacagg aaaaaatttg
      661 acagctaatg atcttattgg caaatcagtc tcagccagca ttgtagaaag tgctgccgaa
      721 gctagtaaga ttgctcaatt tcaaacgaag attgtacgtg taatcaatga tgaagatgac
      781 atggaggaca gcaacagttt catgctgtct catcaaatgg aaacgatttt gaaagaggct
      841 ggatttacga aagctgtatc ttattttatc ttggaactca aagatccatc acagacaaaa
      901 gtagtaacag aagaattaca gaaaaataag aagtatactg tgctttctca acagagagtt
      961 cttgatattg tgattacctt tattcgtgtt attcagggat tattgattgt gctttcatca
     1021 caagctattg tggtagcagc ggttatgatt ggtatcatta tttacatcaa tatcatgcaa
     1081 cgttccaagg aaataggtgt catgaaagca gttggttatc agaatcgtgg tgtcaaagga
     1141 atttttattt acgaggctat ctggattgta ggcatcgcct tgctgctggc atttttggtt
     1201 gcacaagggg tgggaagttt ggcgaatgcg attgtaagtc acttttaccc atccatcact
     1261 aaggtttttg aattaaatct tttatctgtt ttaggaactc tagttttcgc tctattactt
     1321 ggttatgtct cagcctactt cccggcgcgt aagattagta aaatggatcc tgtagaatcg
     1381 ttacgctatg aataataagg gattccttga tttacagtct taaaaagaaa ctcacataga
     1441 aaaacaatgg ccatacttgc aattcaactc aaatagttgt ataataggtt tgttgaaagg
     1501 tgatttgtag tgattcaagt tactcttttc acaataaaaa tttcatgatt ttcataagga
     1561 ggaaatcact aatggtagtt aaagttggta ttaacggttt cggacgtatc ggtcgtcttg
     1621 ctttccgtcg tatccaaaac gtagaaggtg ttgaagttac acgcatcaac gaccttacag
     1681 atccagttat gcttgcacac ttgttgaaat acgacacaac tcaaggtcgt ttcgacggta
     1741 ctgttgaagt taaagaaggt ggatttgaag ttaacggtaa attcatcaaa gtttctgctg
     1801 aacgtgatcc agaacaaatc gactgggcta ctgacggtgt agaaatcgtt cttgaagcta
     1861 ctggtttctt tgctaagaaa gaagcagctg aaaaacacct taaaggtgga gctaaaaaag
     1921 ttgttatcac tgctcctggt ggaaacgacg ttaaaacagt tgtattcaac actaaccacg
     1981 acgttcttga cggtactgaa acagttatct caggtgcttc atgtactaca aactgcttgg
     2041 ctccaatggc taaagctctt caagacaact ttggtgttgt tgaaggattg atgactacta
     2101 tccacgctta cactggtgac caaatgatcc ttgacggacc acaccgtggt ggtgaccttc
     2161 gccgtgctcg cgctggtgct gcaaacatcg ttcctaactc aactggtgct gcaaaagcta
     2221 tcggtcttgt aatcccagaa ttgaatggta aacttgatgg atctgcacaa cgcgttccaa
     2281 ctccaactgg atcagttact gaattggtag cagttcttga aaagaacgtt actgttgatg
     2341 aagtgaacgc agctatgaaa gcagcttcaa acgaatcata cggttacaca gaagatccaa
     2401 tcgtatcttc agatatcgta ggtatgtctt acggttcatt atttgacgca actcaaacta
     2461 aagttcttga cgttgacggt aaacaattgg ttaaagttgt atcatggtac gacaacgaaa
     2521 tgtcatacac tgcacaactt gttcgtactc ttgaatactt cgcaaagatt gctaaataat
     2581 tcttgagttg atagaaagca aggctttgtg gtcttgcttt tttatatgga aaaatggatg
     2641 acacgatcat ccattctttt ttaattcttt ttcaaatgta tttgaaaggg tagtgaaagt
     2701 tagcctctct aaagtaagtg ggtgggtaaa ggaaagtcgg aaggcatgaa gcataagccg
     2761 gcttgtcttt gatttactat tatagagagg gtctcccagg ataggaagat tatgatgcaa
     2821 aaggtgcaca cgaatctgat gggttcgccc tgtctttagc ttgcaatgag ccaaggaagt
     2881 cttgtttgag aattgcttta atctgcttac atgcgtttca gcatattgcc cattttttgc
     2941 atcaactatt ctttttctac gatcatggcg atcacgtcca attttgtctc tgaaaacaag
     3001 ttcttttctg ttgatatttc catcaactag agcccaatat tctctagaaa tctctttttt
     3061 ctccaataag cgattgagaa tgggcaggat aaaaggattt ttggcaaaga gaactaagcc
     3121 actggtttcc atgtccagac gatgaacgac atagcaggtt tggccaacat aggtactgac
     3181 atggttaaga agggcaattt cgtttggttg attaccatgc gttttcatcc cctctggttt
     3241 gtttacaata atcaagtgtt gatcttgata aacttcctgc actaagtctg ggttgcccca
     3301 agggatcgtc ttttggggat aatcttcctc gtcaaaagtc aactggcaaa catctccagg
     3361 atttacgatt tcgttccagc ggacttcttc ttgatttatc aaaatatgtt tcttgattct
     3421 caaaaaatga cggatttttc tagggatgag gagttgttcc tcaagtaatt gctttaccgt
     3481 catttgaggt agagaggcgg gtaatgtaaa tgtgaattgc atacagatat tgtaacaaaa
     3541 aaagccctat ttggatagga aatagctaaa ttcttgtctt cctatgatga agatgataaa
     3601 ataaacgcat gaaattagat aaattatttg agaaatttct ttctcttttt aaaaaagaaa
     3661 caagtgaact agaggactct gattctacta tcttacgtcg ctctcgtagt gatcgaaaaa
     3721 aattagccca agtaggtccg attcgaaaat tctggcgtcg ttatcatcta acaaagatta
     3781 tccttatact aggtttgagt gcaggcttgc tagttggaat ctatttgttt gctgtagcca
     3841 agtcgaccaa tgtcaatgat ttgcaaaatg ccttgaaaac tcggactctt atttttgacc
     3901 gtgaagaaaa agaggctggt gccttgtctg gtcaaaaggg aacctatgtt gagctgactg
     3961 acatcagtaa aaacttgcag aatgctgtta ttgcgacaga agaccgttct ttctataaaa
     4021 atgacgggat taactatggc cgtttcttct tggctattgt cactgctgga cgttcaggtg
     4081 gtggctctac cattacccaa cagctggcta aaaacgccta tttatcgcag gatcaaactg
     4141 ttgagagaaa agcgaaagaa tttttccttg ccttagaatt aagcaaaaaa tatagtaagg
     4201 agcaaattct aaccatgtac cttaacaacg cttattttgg aaatggtgtg tggggtgtag
     4261 aagatgcgag taagaaatac tttggagttt ctgcatcaga agtgagtctg gatcaagctg
     4321 cgactctggc agggatgctc aaggggccgg aactgtataa tcccttgaat tccgtagaag
     4381 attctactaa tcggcgcgat actgtcttgc agaatatggt tgcagcagga tatattgata
     4441 aaaaccaaga aaccgaagct gctgaagttg atatgacttc gcaattgcac gataagtatg
     4501 aaggaaaaat ctcagattac cgttacccct cttattttga tgcggtggtt aatgaagctg
     4561 tttccaagta taatctaaca gaggaagaga ttgtcaataa tggctaccgc atttacacag
     4621 agctggacca aaactaccaa gcaaatatgc agattgttta tgaaaacaca tcgctatttc
     4681 cgagggcaga ggatggaacg tttgctcaat caggaagtgt agctctcgaa ccgaaaacag
     4741 ggggagttcg tggagttgtc ggtcaagttg ctgacaatga taaaactgga ttccggaatt
     4801 tcaactatgc aacccaatca aagcgtagtc ctggttctac aattaagcct ttagttgttt
     4861 atacgccagc agttgaagca ggctgggctt tgaataagca gttggataac cataccatgc
     4921 agtatgacag ctataaggtt gataactatg cagggatcaa aacgagtcga gaagttccta
     4981 tgtatcaagc cttggcagaa tcgcttaatc tacctgctgt tgccactgtt aatgatttgg
     5041 gtgtcgacaa ggcttttgag gcaggcgaaa aattcggact caacatggaa aaggtcgacc
     5101 gtgttcttgg tgtcgccttg ggaagcggtg ttgaaaccaa ccctcttcaa atggctcaag
     5161 catacgctgc ctttgcaaat gaaggtttaa tgcctgaagc tcattttatt agtagaattg
     5221 aaaatgctag tggacaagtt attgcgaatc ataaaaattc acaaaaacgg gtgattgata
     5281 agtctgtagc tgacaagatg accagtatga tgttggggac tttcaccaac ggtaccggta
     5341 ttagttcatc gcctgcagac tatgtcatgg cagggaaaac tggaacaact gaagcagttt
     5401 tcaatccgga gtacacaagt gaccagtggg taattggtta tactccggat gtagtgatta
     5461 gccactggct tggctttccg accactgatg aaaatcacta tctagctggc tctacttcaa
     5521 acggtgcagc tcatgtcttt agaaacattg ccaataccat tttaccttat acgccaggaa
     5581 gtacctttac ggttgaaaat gcttataagc aaaatggaat tgcaccagcc aatacaaaaa
     5641 gacaagtaca aaccaatgat aatagccaga cagatgataa tttgtctgat attcgagggc
     5701 gtgcgcaaag tctagtagat gaggctagcc gggctatctc agatgcgaag attaaggaaa
     5761 aggctcaaac aatatgggat tcgatagtca atctatttcg ctaagatgct tgtcaaagcc
     5821 tagctttctt gttataatgg ataagatgga ggcgttatgg cactaaaaaa agcaagccta
     5881 gcttgtgcgg tttgtggttc gagaaactat tcaatcaaga tcagcggaaa ccccaagcct
     5941 acacgactag aagtaaataa attttgtaag cattgtggca agtacactac acacagagaa
     6001 acgagatagg agagagcgat gcgttttatt ggagatattt ttagacttct taaagacaca
     6061 acatggccaa ctcgcaagga aagctggaga gattttcgtt ctatcatgga atacacagct
     6121 ttctttgtag taattattta catttttgac cagttgattg tttcaggttt gattcgattt
     6181 attaacattt tttagaagat tagtggagtt aattacacta gaaatcttct atttatgaaa
     6241 ggaaatatca tggatagttt tgataaagga tggtttgttt tacaaactta ttctggttat
     6301 gaaaataagg tgaaagaaaa tctattacaa cgtgcacaaa cctacaatat gttggataat
     6361 attctacgcg ttgaaattcc aacacaaaca gtgcaagttg aaaaaaatgg aaagagaaaa
     6421 gaagtagaag aaaatcgctt tccaggttat gttcttgtag aaatggtcat gacagatgaa
     6481 gcttggtttg ttgttcgaaa cacaccaaat gttacaggat ttgtcggatc acacgggaac
     6541 agatcaaaac caactccatt attggaacaa gaaattcgtg acattttggt atctatggga
     6601 caaactgttc aagaatttga tttcgatgtt gagattggtc aaactgtacg tattattgat
     6661 ggtgcttttg cagactacac tggtaagatt acagaaattg ataataacaa agtgaaaatg
     6721 attatctcta tgtttggtaa tgacacagtt gcagaagtaa acctaaacca aatcgcagaa
     6781 t
//
LOCUS       DBEJKC010000077         6728 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.077, whole genome shotgun sequence.
ACCESSION   DBEJKC010000077 DBEJKC010000000
VERSION     DBEJKC010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6728
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.077"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(184..1267)
                     /gene="glf"
                     /locus_tag="ACL3G6_001893"
                     /pseudo
     CDS             complement(184..1267)
                     /gene="glf"
                     /locus_tag="ACL3G6_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272499.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0008767 - UDP-galactopyranose mutase
                     activity [Evidence IEA];
                     GO_process: GO:0009273 - peptidoglycan-based cell wall
                     biogenesis [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(1330..2181)
                     /gene="rfbD"
                     /locus_tag="ACL3G6_001894"
     CDS             complement(1330..2181)
                     /gene="rfbD"
                     /locus_tag="ACL3G6_001894"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HGR0546368.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            complement(2247..3296)
                     /gene="rfbB"
                     /locus_tag="ACL3G6_001895"
     CDS             complement(2247..3296)
                     /gene="rfbB"
                     /locus_tag="ACL3G6_001895"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HGR0546369.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPGVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            complement(3309..3902)
                     /locus_tag="ACL3G6_001896"
     CDS             complement(3309..3902)
                     /locus_tag="ACL3G6_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018029578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HGR0546370.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDL"
     gene            complement(3903..4772)
                     /gene="rfbA"
                     /locus_tag="ACL3G6_001897"
     CDS             complement(3903..4772)
                     /gene="rfbA"
                     /locus_tag="ACL3G6_001897"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HGR0546371.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFISDDSV
                     ALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLTLAQPLKKN
                     EYGQYLLRLIGEA"
     gene            complement(4799..5899)
                     /gene="glf"
                     /locus_tag="ACL3G6_001898"
     CDS             complement(4799..5899)
                     /gene="glf"
                     /locus_tag="ACL3G6_001898"
                     /EC_number="5.4.99.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008767 - UDP-galactopyranose mutase
                     activity [Evidence IEA];
                     GO_process: GO:0009273 - peptidoglycan-based cell wall
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="HGR0546372.1"
                     /translation="MYDYLIVGAGLSGAIFAHEATKRGKKVKVIDKRDHIGGNIYCEN
                     VEGINVHKYGAHIFHTSNKKVWDYVNQFAEFNNYINSPVANYKGSLYNLPFNMNTFYA
                     MWGTKTPQEVKDKIAEQTAGMKDVEPKNLEEQAIKLIGPDIYEKLIKGYTEKQWGRSA
                     IELPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGVDFFAHRE
                     ELEASANKVVFTGMIDQYFDYKHGELEYRSLRFEHEILDEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGMQPKTVITHEYPADWKRGDEPYYPINDEKNNAMFAKYQEEAAQNDK
                     VIFCGRLADYKYYDMHVVIERALEVVEKEFSN"
     gene            complement(5902..>6728)
                     /locus_tag="ACL3G6_001899"
     CDS             complement(5902..>6728)
                     /locus_tag="ACL3G6_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000107550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HGR0546373.1"
                     /translation="IRRHLKPIFVLLGSVIAIEIYTMLDTTMIGAMVGTTEVGYYTNS
                     MKLVKLLITVITAIGGVLLPRLSDYYSKGEFEKLNHIVDKVFRIMLFLFLPAQVALIL
                     VAPVIMPILFGDSFIPAVLTLQLTSLLICTLGFSNLFGTQILLTFGDERKLLISTILG
                     ALSNIALNLILIPVMAQNGAALASVISETIVTLTAYYYAKKRVTIRFDLGFYLPTVVS
                     TIIMGGAIYVVMQLYIGDIEKMLFSTLLGGVVFLLINVFMKNPIIYEFTGIIKRKR"
BASE COUNT         1969 a         1482 c         1119 g         2158 t
ORIGIN      
        1 catatagtca aggaattttt aatactattt ctaaataata actggtagtc agttttactt
       61 gtttatactc ttcgaaaatc tcttcaaacc gcgtcagctt ccatctgcaa cctcaaaaca
      121 gtgttttgag caacctgcgg ctagcttcct agtttgctct ttaattttca ttgagtatga
      181 atctaactca tttctcacgc actgcaaagc tgctccaatt acttggtgca tatcgtaata
      241 acgatagtgt cctaagcggc caccaaagat aacattccct tgctcatcag caagtttttt
      301 atatgattta tacaaatgat tattacgatc attattaact ggataataag gctcatcacc
      361 tttttcccat gttttagaat gttctattag taatgatagt ctttgcttga ctcccaaact
      421 caaaatgttt gtgttcaata atgcgagtat atggggtttc tgcatccgta tagttcacaa
      481 ctgcatttcc ttggtaattt tccatatcca aggtctcatt ttcaaaacga agactacggt
      541 actctagttc gcccaactta tagtcaaaga attcatcaat cataccagta aagacaatct
      601 taggaaaatc tttcagatat tgctctttgt tcacaaagaa atcaacattt gtttctacat
      661 caatattttc atgatccaac atttttcaac tatttgagtg tatccaccaa ttggaatccc
      721 ttgataggta tcgttaaaat agttgttatc ataggtcagg tgtactggta aacagcgaat
      781 aataaaggat ggaagttcag tagttggttt gcccccactg tttctctgta tagtctttga
      841 ttaatttttc gtagatgtct gtacctacaa gagaaatcgc ctgttcttcc aaattttcag
      901 gagttttacc atttaaaata gcacgttgtt catcaatctt agcctgtact tctgctggcg
      961 ttacaactcc ccagagttta ttgaaggtat tcatattaaa aggaaggtta taaatctcac
     1021 ccttatagtt tgcaacagga gaattggtat aacggttaaa ctctgcaaac tgatttacat
     1081 aatcccagat ctccttatca gaagtatgga agatatgagc accatattga tgaacttgaa
     1141 ttccttcctc ttcacgagta tagatattac ccgcgatatg atttcgtttt tcaataactt
     1201 ttactttttt tccttctaag gctgcttcat gggcaaagac tgcaccaaca acaagataat
     1261 cgtacatctt aagctccttt ggagttcatt atctgcctct tttattagac tagaaaatca
     1321 ttctactact tatctcactt cttgtttgta aaattcttgc aatgcatctt gccaagttgg
     1381 aataacaaat ccagtagctt tggctttggc caggctcatc gttgagttta gcggacgttt
     1441 agctttggct ggaaattgac tggaatctac tggcttgact tcgacatctg tatctttcaa
     1501 aatttcaact gcaaaatcat accatgttgt gtcttctgtc gcatcatttg acaaatgata
     1561 ataaccaaat tccttacgat tttcagctag gtaggtcatg aactcagcca aggtacgagt
     1621 ccaagtcgga cgaccgtact ggtcatttac aactgttaaa gtcttatgag ttttcgcaag
     1681 attttgcatg gtaaaaacga agtttttgcc ataatttcca aatacccagg cagtacggat
     1741 aatatagaaa ttagacacat gcttctcaac taactcttcc cccatacgct tagtgcgtcc
     1801 atattctgtc tgtggatctg gtcggtcatc aacttcccac tcttgtccaa ctggtttctt
     1861 accgtcaaag acatagtccg tagaaatata aactagagtt gcaccatgct tttcagatgc
     1921 ttttgcgaca ttttttgtcc ccgtcacatt gatggcgaag tccaactctt ttccttcatc
     1981 ctctgctgca tcaacagcgg tgtaggctgc acagtggtag actaaagtcg gtttcacctc
     2041 ttcaaaaact ttctcaacca tttcttcatt ggtaatgtcc atctcagcca catctactgc
     2101 cacgtattct tcattacgtt catccaataa atagcgaagt tccgttccta attggccatt
     2161 tgcccctgta attaaaatca tctctagacc tttctaatat gtaactcttc tcaatatagc
     2221 aataaaaagc agctatttcc tgctttttat actgtaataa tctcctgagt cttagcataa
     2281 ttggcttcaa cagcttcttt ttctgctttc caccattctt ggttatctgt ataccacttg
     2341 attgttgcct tgagcccagc ttcaaagttg gtaaattcag gtttccaccc caactcatca
     2401 cggagcttgc tggcatcaat cgcatagcga aggtcatgtc ctgcacggtc agtcacatga
     2461 tcataggcat ccgtagcttg tcccatttcc ttaaggataa gttccaaaac ttccttattg
     2521 ttcttctcac catcagcccc aatcaagtag gtttcaccga tttgcccttt tgtcaagatt
     2581 gtccaaactc ctgaagaatg gtcattggta tgaatccagt cacgaacatt cttaccttca
     2641 ccgtaaagtt ttggcttaat tccacttagg atgttagtaa tctgacgtgg gatgaatttt
     2701 tcgatatgtt gataaggacc gtagttattt gaacagttgg aaatcgttgc cttgactcca
     2761 aaagaacgca cccaggcttt gacaatcaaa tctgaggctg ccttggttga tgagtacgga
     2821 gagcttgggt tgtattttgt ttcagcagta aatttctcac ctggtccttc accatgacct
     2881 ggcaaatctt cgcgtaaagg gagatcccca taaacttcat ctgtcgatac atggtggaag
     2941 cgaatatcat acttacgagc agcttctaaa agagtatagg ttccgatgaa gttagtatga
     3001 ataaatggcg atggatcatt gagcgaatta tcattgtggc tttccgctgc ataatgaacg
     3061 atagcatctg cttgagcagc caacttgtct accaactccg catcagcaat gtcaccaaca
     3121 actaactcaa cacgattacc taaaatttcc tcaatattcg cgcgatttcc agcataagtc
     3181 aacttatcta ggactgtcac gtgaacacct ggaaagttct cgtaaacata atggacaaag
     3241 ttagaaccga taaagccagc tccacctgtc acgataatat ttttgtattc agtcatattc
     3301 tttccttttt acaaatcttc ttttttcaaa ggttttacat ccttaagtag gggatgatgt
     3361 ttatctgctt ctgaaacctc tgcttctgca atattttccc attcaatacc aaggcttgga
     3421 tcagcgtagt tcacaaaggc atacttgggt ttgagctcga gagcccagta atcattgacc
     3481 agatagctat atgacactgt atctgataga acttggaagc cattagctac gcctcgagga
     3541 acaaagattc ccttgcttgc atcaattact gtctgatagg tattcccaaa ggtttcaccc
     3601 tcgcgtagat caacccaaga acccagaact ttccctccat ctgctacaga gatgtactta
     3661 tcccaaggct ctgcgtggag tcctcgaagg acatttttac gtgagaagga tacattgttt
     3721 tgcaattttc cttctgcaaa gaaagactct ggaaatccaa gtggaagcat tttttccttt
     3781 tggaaatttt ctttaaacca gccacgatta tctccatgaa cggggatatc aaactccaac
     3841 atgcctggaa tagcttcaac cttgcgtgcc gcaagcgtct taccgaaaaa attatctgtc
     3901 atctatgctt ctccaatcaa acggagcaga tactgtccgt attcattttt cttaagtggt
     3961 tgggctaagg tcaatacatc ttcacgactg atataaccca tgcgataggc aatttcttct
     4021 aagtttgcta cctgaacatt ttgcatccgt tggactgttt cgatgtactg tgaagcctct
     4081 agtaaacttt catgagttcc agtatccagc caagcaaagc cacgtcccat aagctcaaca
     4141 gacaaatcac cacgatctag gtaagctttg tttacatctg taatttccag ttcaccacga
     4201 ggacttggtt taatactctt ggcaatctct actacatcat tatcatagaa atagagacct
     4261 gtaactgcat agtttgaacg aggttgctct ggcttttctt caatagaaat agccttcata
     4321 tcctgatcaa actcaaccac accaaagcgc tctggatcct tgacatggta gccaaaaaca
     4381 gttgctcccg actccttact cgctgccttt tgtagcatct tggaaagccc agaaccatgg
     4441 tagatattat cacctaagat tagcgcaacg ctatcatcag aaataaactc ttccccaatg
     4501 ataaaggctt gtgccaaacc atctggactt ggttgctcag cataagaaag tttaatacca
     4561 aactcggaac catcttgaag aagctcttta aaacgaggca aatcttgagg agttgagata
     4621 atcaaaatat ccctaatccc agccaacatt aatgttgaaa gtgggtagta aatcatcggt
     4681 ttatcataaa ccggcataag ttgttttgat gcggctcgag tcaaaggata caagcgagtt
     4741 cccgaaccac ctgctagaat aatacctttc ataataagca acctttcttc gttgtttttc
     4801 aattactaaa ttctttctcc acaacctcaa gcgcccgttc aatcaccaca tgcatatcgt
     4861 aatacttata atctgctaaa cgcccacaaa agataacttt atcattctgc gctgcttctt
     4921 cttggtattt agcaaacata gcattatttt tctcatcgtt aataggatag tagggctcgt
     4981 ccccacgctt ccagtcagct ggatattcat gcgtgataac tgtctttggc tgcattccat
     5041 attcaaaatg tttgtgttcg atgatacgag tataagggat ctcacgctct gtatagttca
     5101 ctacagcatt cccttgataa ttttcctcgt ctaaaatctc atgctcaaaa cgaaggctac
     5161 ggtattctaa ctctccgtgc ttgtagtcaa aatattggtc gatcattcct gtgaagacaa
     5221 ctttgttagc agatgcttcc aactcttcac gatgagcaaa aaagtctact ccaagttcaa
     5281 cttctacatc tttcagcata ttttcgatga tgacattgta accaccaata ggaatccctt
     5341 ggtaacggtc attaaaatag ttattatcaa aggttaaacg aactggaagg cgttttatga
     5401 taaatggagg aagttctatc gctgagcgtc cccattgctt ttctgtataa cccttgatca
     5461 acttttcata gatatccgga ccaatcaact tgatagcttg ttcttccaga tttttcggct
     5521 caacatcctt cataccagct gtctgctcag caatcttatc cttcacttct tgtggagttt
     5581 ttgtgcccca catagcatag aaggtattca tattgaaagg aaggttataa agacttccct
     5641 tatagtttgc gacaggtgag ttgatatagt tgttaaactc agcaaattga ttgacgtagt
     5701 cccagacttt tttattagaa gtatggaaga tatgggcacc atatttatga acattgatac
     5761 cttctacatt ctcacagtat atgttccctc caatgtgatc gcgtttatca atcactttta
     5821 ctttttttcc acgctttgta gcttcgtgtg cgaagattgc tccagacaaa cccgctccaa
     5881 cgattaaata gtcgtacata attatctctt tctctttata atacctgtaa attcatatat
     5941 aataggattc ttcataaaaa cgttaattaa aaggaataca acacctccta acaaagttga
     6001 aaataacatt ttttctatat ccccaatata caattgcatt actacatata tagctccacc
     6061 catgattatt gttgaaacaa cagttggcaa ataaaatcct aagtcaaacc taattgtcac
     6121 acgttttttc gcatagtagt atgctgttaa agtaacaatt gtttcactaa tcacagatgc
     6181 caacgctgct ccattttgag ccattactgg aatcagaatt aggttcaaag cgatattact
     6241 aagcgctcct aaaattgtgc taatcaaaag ctttcgctca tctccaaatg ttagtaatat
     6301 ttgagtccca aataaattac taaaccctaa tgtacatata agcaaagaag taagttgaag
     6361 tgttaacact gctggtataa aactatcacc aaataaaatc ggcataatta ctggtgcaac
     6421 tagaattaat gcaacttggg ctggtaaaaa aagaaacaac atgattctaa aaactttatc
     6481 aacgatgtga tttaattttt caaattctcc cttagaataa taatcactta gtcgtggtaa
     6541 aagcactcct ccaatagcgg taatcacagt tatcagcaat ttaactagct tcatagaatt
     6601 tgtataataa cctacctcag tcgttcctac catagcacca atcatagtgg tatccagcat
     6661 agtatagatt tcaatagcaa tcactgaacc caacaaaaca aaaataggtt ttaagtgtct
     6721 tctaatct
//
LOCUS       DBEJKC010000078         6677 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.078, whole genome shotgun sequence.
ACCESSION   DBEJKC010000078 DBEJKC010000000
VERSION     DBEJKC010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6677
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.078"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(29..292)
                     /locus_tag="ACL3G6_001900"
                     /pseudo
     CDS             complement(29..292)
                     /locus_tag="ACL3G6_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            486..2252
                     /gene="patB"
                     /locus_tag="ACL3G6_001901"
     CDS             486..2252
                     /gene="patB"
                     /locus_tag="ACL3G6_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HGR0546374.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTENKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            2391..3080
                     /locus_tag="ACL3G6_001902"
     CDS             2391..3080
                     /locus_tag="ACL3G6_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGR0546375.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQIGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            3084..3263
                     /locus_tag="ACL3G6_001903"
     CDS             3084..3263
                     /locus_tag="ACL3G6_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546376.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            3250..4599
                     /locus_tag="ACL3G6_001904"
     CDS             3250..4599
                     /locus_tag="ACL3G6_001904"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HGR0546377.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            4723..6183
                     /gene="gltX"
                     /locus_tag="ACL3G6_001905"
     CDS             4723..6183
                     /gene="gltX"
                     /locus_tag="ACL3G6_001905"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HGR0546378.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYSRHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWIIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            6197..6631
                     /locus_tag="ACL3G6_001906"
     CDS             6197..6631
                     /locus_tag="ACL3G6_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGR0546379.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         2090 a         1294 c         1432 g         1861 t
ORIGIN      
        1 cgcatgcttt ggcagcttgt atgagtgcct accgcagatg aggggaaccc cgtttgatca
       61 ttcttccagc taaatcaatc tgacctgact gataaataga agaatccagt ccagcgaaag
      121 cttgtaattg agcaggatta tcaaaggcat gaatattttg aatctcggct aaaatgaccg
      181 cccctaaacg attcccaatc ccagtaaccg tcgtgatgac cgaatttaac tcagccatca
      241 agtcattgac acatttttcc gccttgtcaa tgaacctctt gtaatgtttg atgttttcat
      301 tacacgagat aaaacgtcta tgcgttatca aactcattac caattaaaac aaatgtggtt
      361 agatcctttc ggaaattgtc aagcgattgg aggaaatgaa ctaatccaca gcggcttatt
      421 ccaagtatac cacttgggct ttggcagtag ctaactgcgc taaatataat ataaggagga
      481 gtaaaatgaa gacagttcaa tttttttggc attattttaa ggtctacaag ttctcatttg
      541 tagttgtcat cctgatgatt gttctggcga cttttgccca agccctcttt ccagtctttt
      601 ctggacaagc ggtgacgcag ctagccaatt tagttcaagc ttatcaaaat ggcaatccag
      661 aacttgtatg gcaaagccta tcaggaatca tggtcaatct tggcctgctg gttttggttc
      721 tatttatctc tagtgtaata tacatgtgtc tcatgacgcg cgtgattgca gaatcgacca
      781 acgagatgcg caaaggtctc tttggtaagc ttgctcagtt gacggtttct ttctttgacc
      841 gtcgacaaga tggcgatatc ctgtctcatt ttaccagtga tttggataat atcctccaag
      901 cctttaacga aagcttgatt caggtcatga gcaatattgt tttatacatt ggtctgattc
      961 ttgtcatgtt ttcgagaaat gtgacgctgg ctctcatcac cattgccagc accccattgg
     1021 ctttccttat gctgattttc atcgtgaaaa tggcacgcaa atacaccaac ctccagcaga
     1081 aagaggtagg gaagctcaac gcctatatgg atgagagcat ctcaggccaa aaagccgtga
     1141 ttgtgcaagg aattcaagag gatatgatgg caggatttct tgaacaaaat gagcgcgtgc
     1201 gcaaggcaac ctttaaagga agaatgttct caggaattct tttccctgtc atgaatggga
     1261 tgagcctgat taatacagcc atcgtcatct ttgctggttc ggctgtactt ttgaatgata
     1321 agtctattga aacaagtaca gccctaggtt tgattgttat gtttgcacaa ttttcacagc
     1381 agtactacca gcctattatc caagttgcag cgagttgggg aagccttcag ttggccttta
     1441 ctggagctga acgaattcag gaaatgtttg atgcagagga ggaaatccga cctgaaaagg
     1501 ctccaacctt cactaagttg caagaaagtg ttgaaatcag tcatatcgat ttttcatact
     1561 tgcctgataa acctattttg aaagatgtca gcatttctgc ccctaaaggc cagatgacag
     1621 cagttgttgg gccgacaggt tcaggaaaaa cgactattat gaacctcatc aatcgctttt
     1681 atgatgttga tgctggtggt atttattttg atggtaaaga cattcgtggc tatgacttag
     1741 atagtcttag aagcaaggtg ggaattgtat tgcaagattc ggtcttgttt agcggaacga
     1801 ttcgagacaa tatccgattt ggtgtgccag atgctagtca ggaaatggtt gaggtagcag
     1861 caaaagcaac ccacattcac gactatatcg aaagtttgcc tgataagtac gatactctta
     1921 ttgatgatga ccagagcatc ttttcaacag ggcagaagca attgatttca atcgctcgaa
     1981 ccctgatgac agatccagaa gttctcattc tcgatgaagc aacttcaaac gtagatacgg
     2041 tgacagaaaa caagattcag catgccatgg aggtggttgt agcaggtaga actagtttcg
     2101 tcattgccca ccgcttgaaa accattctca atgcagatca gattattgtc cttaaagatg
     2161 gagaagtcat tgaacgtggt aaccaccatg aacttttgaa gctaggtggc ttttattcag
     2221 aactctatca caatcaattt gttttcgaat aagaaagaag ttgtcctatg tgggcagctt
     2281 tttcttgtcc ataaaaaatg tttatcacag ccttaaaaaa aacatattag acgaaagtca
     2341 ttttgagtga tatgatagga ctatcgttag cattcgaaag gagaggcatc atggctagaa
     2401 cggttgtagg agttgctgca aatctatgtc ccgtagacgc agaaggcaaa atcattcatt
     2461 catctgtatc ttgtagattc gcagagatca ttcgtcaaat cggtggtctc cctttagtca
     2521 ttcctgttgg tgatgagtca gttgtacgtg attatgtgga aatgattgac aaactcattt
     2581 tgacaggagg ccaaaatgtt catcctcagt tttatggaga gaaaaagacc gtcgagagcg
     2641 atgattacaa tctggtccgt gacgaatttg aattggcact cttgaaggaa gcgcttcgtc
     2701 agaataaacc aattatggca atctgtcgcg gtgtccaact tgtcaatgtt gcctttggtg
     2761 gaaccctcaa tcaagaaatc gaaggtcact ggcaaggact acctttcggg acatctcact
     2821 ctattgagac agtagaagga agcgtggtgg ctaagctatt tgggaaagaa agtcaggtca
     2881 actcagtcca tcgtcaaagc attaaagatt tggcacctaa tttccgtgta actgctattg
     2941 attcaagaga ccaaactatt gaagcgattg agtctatcga cgagcaccgc attatcggtt
     3001 tacagtggca tccagagttt ctggttaatg aagaagatgg caatttagaa ttatttgagt
     3061 atttattgaa tgaactgtaa cgattggaac atctggtcgt tctttctttt attttttcaa
     3121 aatttttaga atgtggcatt ttacgcaaac gtttgaattc tgataaaaat tggagaaatt
     3181 cgacaaaaaa acttgaaaaa aacgaaggta agcgttatga tagaaaagaa gaaatattgg
     3241 aggaagaaca tgtcacatat taaatttgat tattcaaaag ttttagacaa atttgttgca
     3301 ccacatgaag tggaatacat gcaatcacaa gtaacagcag cagatgaatt gatccgtaaa
     3361 ggaactggtg ctggtagcga cttcttggga tggttggacc ttcctgaaaa atacgatcgc
     3421 gaagaatttg accgcatctt gaaagctgct gagcaaatca agtcagacag cgatgttttg
     3481 gttgtgatcg gtattggtgg atcttacctt ggtgcaaaag cagcaatcga cttcttgaat
     3541 caccattttg ctaacttgca aacaaaagaa gaacgcaaag ctccacaaat cctttacgca
     3601 ggaaactcaa tctcatctac ttaccttgct gacttggtag agtatgttgc agacaaagac
     3661 ttctcagtaa acgtaatttc taaatcaggt acaacaactg aaccagcgat tgctttccgt
     3721 gtctttaaag aactcttggt taagaaatac ggtcaagaag aagctaacaa acgtatctat
     3781 gcaacaactg accgccaaaa gggtgctgtt aaggttgaag cagacgctaa cggttgggga
     3841 acatttgttg ttccagatga tatcggtgga cgcttctcag tattgacagc cgttggtttg
     3901 cttccaatcg cagcatcagg agctgacatc aaagctctta tggaaggtgc gaatgcagct
     3961 cgcaaagact acacttcaga caaaatctct gaaaacgaag cttaccaata cgcagctgtt
     4021 cggaacatcc tttatcgtaa aggctatgca actgagatct tggtaaacta tgagccatca
     4081 cttcaatact tctcagaatg gtggaaacaa ttggctggtg aatcagaagg aaaagaccaa
     4141 aaaggtatct acccaacttc agccaacttc tcaactgact tgcactcact tggtcaattt
     4201 atccaagaag gaactcgtat catgtttgaa acagttgtcc gtgttgacaa acctcgtaaa
     4261 aacgtgctta ttcctacttt ggaagaagac cttgacggac ttggttacct tcaaggaaaa
     4321 gacgttgact ttgtaaacaa aaaagcaact gacggtgttc ttcttgccca cacagatggt
     4381 gatgtaccaa acatgtatgt gactcttcca gagcaagacg ctttcactct tggttacact
     4441 atctacttct tcgaattggc aattgccctt tcaggttact tgaatgctat caacccattt
     4501 gaccaaccag gtgttgaagc ttataaacgt aacatgtttg cccttcttgg aaaaccagga
     4561 tttgaagaat tgagcaaaga acttaacgca cgtctataat agaagaaaag agtggtttgc
     4621 ccactctttt tactctcttt atccatagaa attggactca gccaagactt gtgatataat
     4681 atagaaagca aaaaggcaga cgcctagata ataggagaaa ctatgtcaaa agatatccgc
     4741 gtacgttacg caccaagtcc aacaggacta ctacacatcg gaaatgctcg tacagcattg
     4801 tttaattact tgtattcgcg ccatcatggt ggaacatttc tcatccgtat cgaagatact
     4861 gaccgtaaac gccatgtcga ggatggtgaa cgttcacaac ttgaaaacct tcgctggtta
     4921 ggcatggatt gggatgaaag tccagaatca catgagaatt atcgccagtc tgagcgtttg
     4981 gacttgtatc aaaaatacat tgaccaacta ttagctgaag gaaaagccta taaatcttac
     5041 gttacagaag aagagttggc agctgaacgc gaacgccaag aagtagctgg cgaaacacca
     5101 cgctacatca atgaatacct tggtatgagt gaagaagaaa aagcagctta catcgcagaa
     5161 cgtgaagcag cagggatcat cccaactgtt cgtttggctg tcaatgagtc aggtatctac
     5221 aagtggcatg atatggtcaa aggcgatatc gaatttgaag gtggcaatat cggtggtgac
     5281 tggattatcc aaaagaaaga cggttaccca acttacaact ttgccgttgc catcgatgac
     5341 catgatatgc aaatctctca tgttatccgt ggagacgacc atattgctaa cacaccaaaa
     5401 cagctcatgg tttatgaagc acttggttgg gaagctccag agtttggtca catgaccttg
     5461 attatcaact ctgagactgg taagaagtta tctaaacgtg atactaatac acttcaattt
     5521 atcgaagatt accgaaagaa aggttacctt ccagaagcag tctttaactt tattgctctt
     5581 cttggttgga acccaggtgg tgaagatgag attttctctc gtgaagaact cattaaactt
     5641 tttgatgaaa accgcctcag caagtcacca gcagcctttg atcagaaaaa actagactgg
     5701 atgagcaatg attatatcaa gaatgcagac cttgaaacca tctttgaaat ggcaaaacca
     5761 ttcttagagg aagcaggccg tttgactgac aaggctgaaa aattagttga gctctataaa
     5821 ccacaaatga aatcagtaga tgagattatc ccattgacag atcttttctt ctcagatttc
     5881 ccagaattga cagaagcaga gcgcgaagtc atgacgggtg aaacagttcc aacagttctt
     5941 gaagcattca aagcaaaact tgaagcgatg acagatgata aatttgtgac agaaaatatc
     6001 ttcccacaaa ttaaagcagt tcaaaaagaa acaggtatta aagggaaaaa tcttttcatg
     6061 cctattcgta tcgcagtttc aggcgaaatg catgggccag aattaccaga tacaattttc
     6121 ttgcttggac gtgaaaaatc aattcagcat atcgaaaaca tgctaaaaga aatctctaaa
     6181 taaagaggat acaataatgg acatctggga aaagatgtac gaagaagcac agaaactata
     6241 caatccacat gaagtatcag actttgttta tgccaatcat gttgtagctg cagtagaagc
     6301 agaagatgga caaatattta caggattctg tatggaggga acctgtggtg ttttccatct
     6361 ctgcgcagaa cgggcggccc tcttcaatat gtaccaattt tcaggacaaa ctaaggttaa
     6421 gaaagtatta gcctttcgag acaaaccacc ttatggtgga agttcagcca tgccttgcgg
     6481 tgcttgtaga gaattccttt tagagcttaa tgctgaaaat aaagatgcag aattcatgat
     6541 ggactataat ataagaaaaa cagttaaagt cgcagaacta atcccttatt ggtggggaga
     6601 agaacgtgct tctaagttta atgagcgata gaagagtcag tataattctg gcttttttta
     6661 ctataagttg aaaaaat
//
LOCUS       DBEJKC010000079         6673 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.079, whole genome shotgun sequence.
ACCESSION   DBEJKC010000079 DBEJKC010000000
VERSION     DBEJKC010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6673
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.079"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..422
                     /locus_tag="ACL3G6_001907"
                     /pseudo
     CDS             1..422
                     /locus_tag="ACL3G6_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            589..789
                     /locus_tag="ACL3G6_001908"
     CDS             589..789
                     /locus_tag="ACL3G6_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546380.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            831..1235
                     /locus_tag="ACL3G6_001909"
     CDS             831..1235
                     /locus_tag="ACL3G6_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane domain-containing protein"
                     /protein_id="HGR0546381.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1466..2173
                     /gene="ccdA2"
                     /locus_tag="ACL3G6_001910"
     CDS             1466..2173
                     /gene="ccdA2"
                     /locus_tag="ACL3G6_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGR0546382.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDFNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2184..2741
                     /gene="sdbB"
                     /locus_tag="ACL3G6_001911"
     CDS             2184..2741
                     /gene="sdbB"
                     /locus_tag="ACL3G6_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HGR0546383.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIS
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            3115..4506
                     /locus_tag="ACL3G6_001912"
     CDS             3115..4506
                     /locus_tag="ACL3G6_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGR0546384.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4649..5566
                     /gene="adcAII"
                     /locus_tag="ACL3G6_001913"
     CDS             4649..5566
                     /gene="adcAII"
                     /locus_tag="ACL3G6_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HGR0546385.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLAEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSVLAEELK"
     gene            5574..>6673
                     /gene="phtB"
                     /locus_tag="ACL3G6_001914"
     CDS             5574..>6673
                     /gene="phtB"
                     /locus_tag="ACL3G6_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HGR0546386.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVLKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAQAYWNGKQGSRPSSSSSYNANTAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSL"
BASE COUNT         2043 a         1225 c         1404 g         2001 t
ORIGIN      
        1 acgcttattt gactgaaata gcttctgaat ttggctgtca tccaactacc atccactatg
       61 cgttcaaagc tatgggctac actcgaaaaa aagaaccaca cctactatga acaagaccca
      121 gaaaagtagc cttatttctt aagaatttta atagtttaaa gcacctagca cctgtttaga
      181 ttgatgaaac aggattcgat acttattttt atcgagaata tggtcgctca ttaaaaggtc
      241 agttaagaag aggcaaagta tctggaagaa gatatcagag gatttctttg gttgcaggtc
      301 taacaaatgg tgaattaatc gctccaatga cttacgaaga gatgatgacg agcgactttt
      361 ttgaagtatg gtttcagaag tttttcttac caacattaac cacaccatcg gttattatag
      421 taaaatgaaa taagaatagg acaaatcgat caggacagta aaatcgaatt ctaacaatgt
      481 tttagaagtc catatgtact attctagttt caatatacca taactgttcc tagtcaacct
      541 gcaagccctg tcccagctcc aagctcagct ccgactcaag atcctagagt ggtagcaagc
      601 gcttcggcta gctcaacgag cacacaagct caagagcaag ttgacaagtc tgaacttcgt
      661 gccttgagtc aagagttaga ccaacgcttg aaagctttgg caacagtatc tgatccgaaa
      721 atcgatgcaa ccaaggctgt cctcctagat gctcaaaaag ctccggaaga tagtgccttg
      781 acagagtaag gtctgcatac tgcagtagag tctgtgaagg ctgggctgcc ttggactctc
      841 tcaaagatgt gaaagcaaat gctagcgaca gcaagcctgc acaggacaag aaggatgcaa
      901 aacaaggaac ggaagatagt aaggattcag ataagatgac tgaaacaaac tcagttccgg
      961 caggagtgat tgtggtcagt ctacttgccc tcctaggcgt gattgccttc tggctgattc
     1021 gccgtaagaa agagtcagaa atccagcaat taagcacgga attgatcaag gttctaggac
     1081 agctagatgc agaaaaagcg gataaaaaag tccttgccaa agcccaaaac cttctccaag
     1141 aaacccttga tttcgtgaaa gaagaaaatg gctcagcaga gacagaaact aaactagtag
     1201 aggagcttaa agcaatcctt gacaaactca agtaaaacat gatttatgaa atgtcagacc
     1261 taaaagacat tttcgttcac aaaagcagcg atgagtaatc cttgtcgttg ctttttggct
     1321 attttggggg ataagatccg ccttgactag caaaagaaaa gattggtcca atagtgcccg
     1381 atacgatttt gcgtagcaga aagcttacaa ataaaattga atatagtaaa ataggattag
     1441 aattattaag aaagttggtt ctttattgga aacgatagta tttttaatct ctgtttttct
     1501 agcaggtgtt ttatcctttt tttctccttg tatttttcct cttctgccag tctatgctgg
     1561 gattttattg gatgatcaag aaagtgcaaa aagcttttct ttgtttggga gaaaggttct
     1621 ctggtcaggc ttgattcgaa cactttgctt tatcgctggt atctctctca ttttctttat
     1681 tctaggcttt ggtgctggtt actttggtca tattctctat gcaaattggt ttcgatatgt
     1741 catgggagct attattatca ttttgggtct tcaccagatg gaaatttttc atttgaagaa
     1801 attagaagtt caaaaaagtt ttacctttaa aaaatcagat tttaatcgtt attggtcagc
     1861 ttttttactt ggtattacct ttagctttgg ttggacacct tgtattggtc cagttttaag
     1921 ttctgtttta gcacttgcgg cttctggagg caatggtgct tggcaaggag cgatttatac
     1981 tctcatttac actctgggca tggcccttcc tttcttggtc ttggcactag cttcaggtct
     2041 agtcatgcca tattttagta aaatcaagcg tcatatgatg ctactaaaga aaattggtgg
     2101 tttcctcatt gttttaatgg gaattttgtt actattagga caagtaaatg ttctagctgg
     2161 aatttttgaa taaaggagga caaatgaaaa aagtaatgtt tgctggctta agtctcttgt
     2221 cattagttgt attgatggcc tgtggtgagg aagaaactaa aaagactcaa gcagcacaac
     2281 agccaaaaca acaaacgact gtacaacaaa tttctgttgg aaaagatgct ccagacttta
     2341 cattgcaatc catggatggc aaagaagtta agttatctga ttttaagggt aaaaaggttt
     2401 acttgaagtt ttgggcttca tggtgtggtc catgcaagaa aagtatgcca gagttgatgg
     2461 aactagcggc gaaaccagat cgtgatttcg aaattcttac tgtcattgca ccaggaattc
     2521 aaggtgaaaa aactgttgag caattcccac aatggttcca ggaacaagga tataaggata
     2581 tcccagttct ttatgatacc aaagcaacca ccttccaagc ttatcaaatt cgaagcattc
     2641 ctacagaata tttaattgat agccaaggaa agattggaaa gattcaattt ggtgctatca
     2701 gtaatgcgga tgcagaagca gcatttaaag aaatgaacta gaatcgataa aatctgatta
     2761 caagatgtag tcagattttg gtaacttcta aaactaactt ccagtttccc acaacctagc
     2821 ttttagtatg agaaaaacgc gtgacatcag tggaaatccg tcttagacta acttccactg
     2881 gttttctttt tcttgatata taagggttca aaagcgaaaa gactcagaaa aagtgcacga
     2941 caaatagccc taaaacagag tcgtcttaga gtaacttcca gttttgggag agagatggaa
     3001 gttactttga gaagttacgg tagtcagatt tttttagaaa aacattttat aaatattcac
     3061 atatctccta tatttatggt aaaatagaat tatcagttta ttttggagtc aaagatgaat
     3121 atatttagaa caaagaatgt tagtttagat aaaacagaga tgcataggca tttgaagtta
     3181 tgggatttga ttttgctggg tatcggagcc atggtaggga caggcgtctt tacaatcaca
     3241 ggtactgcag ctgcaacact tgctggccca gccctagtga tttcaatcgt tatttctgcc
     3301 ttgtgtgtgg gattatcagc cctctttttt gcagaatttg cctcgcgagt acccgctaca
     3361 ggaggtgcct atagttacct ctatgctatc ttaggagaat tccctgcctg gttggctggt
     3421 tggttaacca tgatggagtt catgacagcc atatcaggcg tagcttcggg ttgggcagct
     3481 tattttaaag gcttgctctc tcaatacggg atagcctttc ctcaggcttt aaatggtacc
     3541 tttaatcctc aagcagggac atttgttgat ttattgccta ttcttgtctt ggtcttggtg
     3601 acttcgcttg ttttactaaa tgccaaggca gccttacgct ttaattcgat tctagttatt
     3661 ttgaaatttt ccgctttagc tctctttgtt ttagtaggaa tttggaatat taagtttgat
     3721 aattggagca attttgctcc ttacggtttt ggacaaatct atggagctag tactggtatt
     3781 atggctggtg catccttgat gttcttcggt tttttgggat ttgaatccat ctctatggct
     3841 gtagatgaag tcaagactcc tcaaaaaaat attcctagag ggattgtctt atcgctttct
     3901 atcgtaacca ttctctatgc cttggtgacc cttgttttga ctggtgtggt tcactatagt
     3961 catttaaatg tcgatgatgc cgttgccttt gcccttcgta gtgttgggat tagttgggca
     4021 gccaactatg tgtcattagt ggctatcttg accttgatta cagtttgtat ttcgatgacc
     4081 tatgccctat cgcgtatgat ttacagttta gcacgtgacg gcttagtgcc tgctgccttt
     4141 aaggaactga cgaagactag caaggtacca aagaatgcta ctatcttgac aggtctagct
     4201 tcagcagtag cagcaggaat gttcccacta gccagtattg cagccttttt aaatatttgt
     4261 accttagcct acttgatcat gttggcttat ggtctgattc gcttacggaa agaaaaagga
     4321 atgcccaaag ctggggaatt taaaacacca ttggtacctc tgttaccaat tttatcgatc
     4381 atcatttgtt tatccttcat gttacagtat aatatgaata cctggattgc tttcctagtt
     4441 gcgttgttag taggaagtat tatttacttc acttatggct ataagcattc taccatagaa
     4501 gaataaagtg aaagtctatt gagttgttga cactcagcag atttttatat gtgaaagaaa
     4561 tttcaaattt tttctaaaaa tatcttgaca gattaaattt tcaggagtag aatatttact
     4621 agttaattaa atggttaagg agttgttcat gaagaaacaa aatttatttt tagtcctgtt
     4681 aagtgtcttt cttttgtgct tgggggcttg tggtcaaaag gaaagtcaga caggaaaggg
     4741 gatgaaaatt gtgaccagtt tttatcctat ctacgctatg gttaaggaag tatctggtga
     4801 cttgaatgat gttcggatga ttcagtcaag tagtggtatt cactcctttg aaccttcggc
     4861 aaatgatatc gcagccatct atgatgcaga tgtctttgtt taccattctc atacactcga
     4921 atcttgggca ggaagtctgg atcccaatct aaaaaaatcc aaagtgaagg tcttagaggc
     4981 ttctgaggga atgaccttgg aacgtgtccc tggactagag gatgtggaag caggggatgg
     5041 agttgatgaa aaaacgctct atgaccctca cacatggcta gatcctgaaa aagctggaga
     5101 agaagcccaa attatcgctg ataaactttc agaggtggat agtgagcata aagagactta
     5161 tcaaaaaaat gcgcaagcct ttatcaaaaa agctcaggaa ttgactaaga aattccaacc
     5221 aaaatttgaa aaagcgactc agaaaacatt tgtaacacaa catacagcct tttcttatct
     5281 agcgaagaga tttgggctta atcaacttgg tattgcaggc atctctcctg aacaagaacc
     5341 aagtccacga caattagcag aaattcagga atttgttaaa acctataagg ttaaaacgat
     5401 ttttacagaa agtaatgctt cttcaaaagt agctgaaact cttgtcaaat caacaggtgt
     5461 gggtcttaaa actctgaatc ctttagaggc agacccacaa aatgacaaga cctatttaga
     5521 aaatctggaa gaaaatatga gtgttctagc agaagaatta aagtgaggaa agaatgaaaa
     5581 tcaataaaaa atatctagca ggttcggtgg cagttcttgc cctaagtgtt tgttcctatg
     5641 agcttggacg ttaccaagct ggtcaggata agaaagagtc taatcgagtt gcttatatag
     5701 atggtgatca ggctggtcaa aaggcagaaa acttgacacc agatgaagtc agtaagaggg
     5761 aggggatcaa cgccgaacaa atcgtcatca agattacgga tcaaggttat gtgacctctc
     5821 atggagacca ttatcattac tataatggca aggtccctta tgatgccatc atcagtgaag
     5881 agctcctcat gaaagatccg aattatcagt tgaaggattc agacattgtc aatgaaatca
     5941 agggtggtta tgtccttaag gtaaacggta aatactatgt ttaccttaag gatgcagctc
     6001 atgcggataa tattcggaca aaagaagaga ttaaacgtca gaagcaggaa cgcagtcata
     6061 atcataactc aagagcagat aatgctgttg ctgcagccag agcccaagga cgttatacaa
     6121 cggatgatgg gtatatcttc aatgcatctg atatcattga agatacgggc gatgcctata
     6181 tcgttcctca cggcgaccat taccattaca ttcctaagaa tgagttatca gctagcgagt
     6241 tagctgctgc ccaagcctat tggaatggga agcagggatc tcgtccttct tcaagttcta
     6301 gttataatgc aaatacagct caaccaagat tgtcagagaa ccacaatctg actgtcactc
     6361 caacttatca tcaaaatcaa ggggaaaaca tttcaagcct tttacgtgaa ttgtatgcta
     6421 aacccttatc agaacgccat gtggaatctg atggccttat tttcgaccca gcgcaaatca
     6481 caagtcgaac cgccagaggt gtagctgtcc ctcatggtaa ccattaccac tttatccctt
     6541 atgaacaaat gtctgaattg gaaaaacgaa ttgctcgtat tattcccctt cgttatcgtt
     6601 caaaccattg ggtaccagat tcaagaccag aacaaccaag tccacaatcg actccggaac
     6661 ctagtccaag tct
//
LOCUS       DBEJKC010000080         6207 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.080, whole genome shotgun sequence.
ACCESSION   DBEJKC010000080 DBEJKC010000000
VERSION     DBEJKC010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6207
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.080"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            128..814
                     /locus_tag="ACL3G6_001915"
     CDS             128..814
                     /locus_tag="ACL3G6_001915"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGR0546387.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            815..1747
                     /locus_tag="ACL3G6_001916"
     CDS             815..1747
                     /locus_tag="ACL3G6_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0546388.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFSFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYIGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            1758..2687
                     /locus_tag="ACL3G6_001917"
     CDS             1758..2687
                     /locus_tag="ACL3G6_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0546389.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            2701..4140
                     /locus_tag="ACL3G6_001918"
     CDS             2701..4140
                     /locus_tag="ACL3G6_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546390.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            4209..5786
                     /locus_tag="ACL3G6_001919"
     CDS             4209..5786
                     /locus_tag="ACL3G6_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR0546391.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPKINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            5846..>6207
                     /locus_tag="ACL3G6_001920"
     CDS             5846..>6207
                     /locus_tag="ACL3G6_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGR0546392.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILL"
BASE COUNT         2101 a          852 c         1191 g         2063 t
ORIGIN      
        1 atttctataa attaatttaa ctttcctgat agggctgttc atatcttatt tcaattcact
       61 atataaataa aattgtagta gatgttattg aattagtaaa aaaaataaaa aaacggaggt
      121 tttctgaatg gaaactaaaa aaattaaaaa tttaaaaggt caaataattg tttcctgcca
      181 agcgttagaa ggagagccac tttatactcc aaatggagga gtgatgccgt tattagcaaa
      241 agccgccttt caagcaggcg ctaaaggtat tcgtgctaat tctgtccgcg atatttcaga
      301 aataaaagaa gaagttgact taccaattat aggtatcata aaaagagatt acgatggctt
      361 tgaacctttt atttcagcaa ctatgaaaga gattgatgaa ttagttagtg aaggagtaga
      421 cattttagct ttggattgta ctaatcgttc aagaccaggt tatgataata ttactgactt
      481 tattcatgat attaaagtca agtatccaaa ccaattatta atggctgata tttctacttt
      541 tgaagaaggg aaagtagctg ctgaatcggg agtagatttt gtgggtacga cattatctgg
      601 ttatacacca tatagcccta aaaaagataa tcctgatttt gagttagttg aaagattggt
      661 aaaagagctt gacgtaccag ttattgctga aggaagaata agtactccgg aacaagctag
      721 aaaaatgtta gatttaggtg cttacgcagt ggttgttgga ggagctatca ctcgtccttt
      781 ggaaatagcg aagaagttta ttgaggtagt ttagatgaat caagaaatat taaaaaagag
      841 taagattcaa ttgacagttg aacatattca aaaatattgg attttatatt taatgatgat
      901 tccagcaact gttctactaa ttttatttac gtatggacca atgtacggca ttattatggc
      961 ctttcaagac tttactgtct tcaagggata tactggaagt ccatttgtcg gtttaaaaca
     1021 ttttcaaaga ttgttctcag atcctttgtt ttatagattg ttcaagaata cgttcatggt
     1081 aggggtttta gactttttat tctctttccc agctccgctt atttttgcac tcatattaaa
     1141 cgaagtcaga aaagtaagat ttaagagtgt agttcaatct attagttatc ttcctcattt
     1201 tattccccta gtggttatgg ttggtattat ttttgaacta tttggttcat atggtattat
     1261 taacagttta ctttcatcac ttggaatgga gccaataagt ttctttacaa aatctgaatg
     1321 gttcttgcct ctctacattg gttcaggagt atggaaaaca ataggttggg gttctatcat
     1381 ttatattgga gcattaacca atatagattc aactttatat gaagcagcag atatggacgg
     1441 ggctaataga tggcacaaaa tgtggcatgt aactctacca agtttaagac ctacagtagt
     1501 tactttgttt atactaaatg ctggtggtat catgcaagta ggatttgaaa aggtattctt
     1561 gatgtctagt cctgcaacat atgaagtatc tgatgtatta tctacttatg tttatagaca
     1621 aggtatttta aattctgatt tcagttactc agctgcagta ggattattta ataacatagt
     1681 agctttgtta tttgttttat tagctaataa gattgctaaa aaacttggcg aagaaggaat
     1741 tgtataaggg gggtaaaatg attttttcaa aaaatacaaa aaagagtaat agagacaaag
     1801 aaaccttcgt tgattatctc tttatattca ttttaataat aataacctta cttatgttgt
     1861 atccattatg gtgggtagtg atgacgtcac tttcagaacc agtttggcta tctaaaaacg
     1921 ttgttaaatt atttccctta aaaatagata ttactgcata taagtttatt tttggggatt
     1981 ctaaactatg gcaagcatat ggtaatagtg tattgtatgc tgcactatct acaattgtta
     2041 gtgttgcggt atgtagtatg tatgcctatc cacttacaat tcctgaaatt aggggtaaaa
     2101 aattctggaa tactcttatt ttgattccaa tgttctttag tggaggaatg atcccgcttt
     2161 atatacaagt tgcaaacctc ggtttattga atactgcttg ggctcttgtt ttacctggtg
     2221 ctgtttctac atattatata attttgttta gaacacagtt taaatcaatc ccaatggagc
     2281 ttcgtgagtc tgctagaatt gatggggcaa gtgaatttag aattttttgg aatttagtat
     2341 taccattatc aaaagttatt ttcatgatta tagcacttta ttgcatagtt ggttcatgga
     2401 atagttttac tcctccatta ctttatttga atgacgacac taagatgcct ttatctattt
     2461 atttgagaaa tttagttgtt acaaatacaa ctgatactgc tgaattatca ctttctgcag
     2521 gtaatacata ttaccaacaa attgctgctc aaggtggagg tattggtatg cgtattgcta
     2581 ttaagatggg tactattgtt gttagtgtta ttccaattat gatgatttat ccatttattc
     2641 agaaacattt tgttaaggga atcctgctag gttctgtgaa aggttaataa ggtaattatt
     2701 ttgcaaaatt taaaaaaata tcttttatta gatagcggtt tagtagttgg gtatacatta
     2761 gaaaatgctc aattaaaatt aaataagcta aaaaaagata ctgaaaacaa tccactattt
     2821 ggtgaagagt attttgccga aaatcctaaa ttatgggaag ttcgttttga taattcatat
     2881 ccaaacgtta tctatgataa agaattgaaa ttatatagat gttggtatca aacatttgtt
     2941 agtgatgaag caagcgaaga gactccttta gcagaacgtg gagagaagga atacattgtc
     3001 aagtcatcta gaatgacagc actttgctat gctgaaagta aagatggagt aaaatgggaa
     3061 aaaccaaatc tcaatctagt aaaatttaaa ggttcaaaag ataataatat tgttctgatg
     3121 catgcacacg gtgcaggtat catgctagat gaacaggagt tggatcctaa gaaacgatat
     3181 aaattagttt caaaattaga attttctccg aatcttcatt acatggttgt tgttttttca
     3241 gaagacggta ttcattttga cgaacctatt ccatggaaaa aatggaatcc tgcagcagat
     3301 agtcataatt ttccatttag agatccaaaa actggtaaat acgctgttat tacaagaacc
     3361 tgggcaaata acgtacgtct aagtgcaatt actttcagtg atgattttat taattggtca
     3421 gaacctaaag aaatccttag gggagatgga tttgaagatc aaatttattc tatgccagta
     3481 atttcatacg cggatatcta tttaggtttt gcttcaatgt accacgaagg cgacacttta
     3541 aatgaaaact atgataaagt agacttagaa ttgaaattct ctgctaattt ggaacaatgg
     3601 gatagtgtat gtaagggcga ctatctcatt gaaaggggag gtggagtata cccgcagaat
     3661 gctgattttg atgctagttg tattttcacg gctgctccaa taattgaaga tgataagatt
     3721 tggttctact atatgggtgg aaatggtaat cacactggct tccgagaaag ttcattagct
     3781 agaggatata ttaagaaaga ccaatttgct tattatacta ataagagaga aggaattcca
     3841 gctaaaatat ctacagttag cttccaaact tacgatgatg aaatttatat cttagctgat
     3901 attcctgaaa atggttatat taaagttgcg gtaggtacta aatacggtaa tgcttattca
     3961 gattttggtc aggaagatat ctctcttgtt caagtttccg atggtaagta taagttggaa
     4021 tttaataaaa aatctatctt agatttaggt aattctccag ttgcgttcaa atttgaaatc
     4081 gagaatgcaa aattgtatgg tattgaaggt agtattcagc aacactatct caaatattaa
     4141 ccagaataat tcgttaacaa ataatctcta tattagtgga gatagatata taaaatggag
     4201 gtcttattat ggtaaagctt aataaggtat taaaagggag tgttgcattc ctgagtgcaa
     4261 gtttattgct agcagcttgt ggcaataacg ctaattcaaa gcccgctgaa aaaacagctg
     4321 atggtaaaac gaaaatttcg tttctatcta catggcaaat taatgatgtt cgtccgccta
     4381 aagatgaaac acttgttggt caatggttag aagaacagct aggtattgat attgatcttg
     4441 taactattcc tggcgaggga gtaagttcta aagtaaattc tcttattact agtaaccagt
     4501 taccgactgt tttgttgaca acaggagata agagtgatat cgctggtatc aacaaacttg
     4561 gtaaacaggg tgcattctta gatttgtcac aacacatgga caaactacca aactataaga
     4621 agtaccttga aaaaaataat gcattagctc aaatagaaga tgatgaaaaa catatttatg
     4681 ctttcacaaa attctttact gatgagaata tcatgtatac tacaccaatt ctgagaaaag
     4741 acttacttgt tggttcagaa tttgaagatc tttcaaaaat taaaactgtt gatgactata
     4801 caaaagtttt gaaatatttg actgaaaaac aaggttctcc agcatttatt caacgtaatg
     4861 gctatgaagg cttcatgaag cgagttacac cattgtggaa tttaagccat cgtacatact
     4921 atgactatga atcagattca tataaacatc cagttgaaca acctcaattg aaacaattcg
     4981 ttgaatggtt gaaagaatta cgtaaagata acgtacttca ccctgactgg gcagttatga
     5041 aagatgaaac ttgggaaggt ctattggctt ctaacaaggg ttcattcact gttgaccgta
     5101 tgaatatcat tggagataat aactttgata aatcatttga ttggcagcca cttgtttatc
     5161 caaaaattaa tggaaaacgt tatttgcaac cgaaaacacc gtacatttct gattcaggtt
     5221 gggtaatcaa tgccaatgca ccaaaagaag aaattgataa agcgttagaa ttctttaatt
     5281 tcttatacgc tgatgaaaat caagaaaaac ttgctattgg atttgaaggt aaaacattta
     5341 cacgtgaaaa ccctaatact caagcaggta ttaaatggtt gattcaaatt tacggtgaaa
     5401 atgctggaaa tgataaagca gaactgctgt ttaaacatgg taaccaagca tttactcgcg
     5461 ttcaaactaa attagatatt gaggcacagc caggaacatt ccctaaagtt atgtatgatc
     5521 aagtagataa aattaagaaa gatttaggtg gttttagacc agatactccg gttctttcct
     5581 ttacaactga agaattagat gttttaacta aatctgaagc aggattaaat actttctttg
     5641 atgaaaatat tattaaattc attgaaggac aaagagatat gagtgagtgg gattcattta
     5701 tcaatgaagc taaatctaaa gacttggata aagttacaaa agtatataat gatgcctaca
     5761 aacgtgtcaa agatagaatg aaatagacta aatggtagct ctctggtttt tcagagagct
     5821 actactgcct gagggggagt aagctttgta tgatgtagta attataggtg caggaagttc
     5881 gggcgcattg gctgcaattg cttcggggcg tctagggtta aaaacttgtc taatagagaa
     5941 gggaagtaga attggtggag ttcctattaa tacactaatg gggtcatttg ctaatctata
     6001 ttttgatgat tctggtagag taaatgcaag taaaattgtt ggggaattaa tagaacgtat
     6061 tatcaaaaaa ggtggtactg tctttaactc tatggaagaa ttgatgaatg taaatgattt
     6121 ttatcagatt acaattccct atcaaccaga agtttatgaa tcggttttaa ctgatatgtt
     6181 gattgagtct aaagttgata ttttact
//
LOCUS       DBEJKC010000081         6046 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.081, whole genome shotgun sequence.
ACCESSION   DBEJKC010000081 DBEJKC010000000
VERSION     DBEJKC010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6046
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.081"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            29..1783
                     /locus_tag="ACL3G6_001921"
     CDS             29..1783
                     /locus_tag="ACL3G6_001921"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0546393.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNEGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            1767..3488
                     /locus_tag="ACL3G6_001922"
     CDS             1767..3488
                     /locus_tag="ACL3G6_001922"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0546394.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            3499..4128
                     /locus_tag="ACL3G6_001923"
     CDS             3499..4128
                     /locus_tag="ACL3G6_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGR0546395.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYIVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFSNGLYCVGYFTPCLILWCYLN"
     gene            4029..4586
                     /locus_tag="ACL3G6_001924"
     CDS             4029..4586
                     /locus_tag="ACL3G6_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR0546396.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFMAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGINFKNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            4574..5938
                     /locus_tag="ACL3G6_001925"
     CDS             4574..5938
                     /locus_tag="ACL3G6_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0546397.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT         2213 a          764 c         1136 g         1933 t
ORIGIN      
        1 agggatatta aagaaaggag atatgcttat gaagatttac aaaaaactat ttgcttatgt
       61 ccaagataag aaatatcttg gggttttggc cataattttt tctgctatat ctgctctact
      121 tacagtatat ggatattatt taatctacaa atttctagat aagttaataa ttaattcaaa
      181 tttatccggt gcagagagta tagcattaaa atctgttatt acactaacaa gtggagcgat
      241 attttatttt gtctcaggaa tgttttcaca tatcttggga ttcaggcttg aaacaaattt
      301 aagaaaaagg ggaatcgatg gtctggaaaa agcaagtttt aggttctttg acttaaatcc
      361 atctggtcaa ataagaaaga tcatagatga taatgcagca caaactcatc aggtggtagc
      421 acacatgatt cccgatagtt ctcaggcaat aatcacaccc gtacttgtac ttgcacttgg
      481 ctttatagta agtataagag ttggcataat tttgcttgct cttactataa ttggtggctt
      541 aattttaggg gcgatgatgg gcgagcaaga atttatgaag atataccaag aatccctatc
      601 taaactaagt gctgaaactg ttgagtacgt gagaggaatg caagttgtaa aaatatttaa
      661 agcaaatgta gagtcattta aaagctttta caaggctata aaagattact caaagtatgc
      721 ttatgattat tccctatctt gtaaaaggcc ttatgttttg tatcaatggt tattttttgg
      781 actgattgca attttaatta ttcctatagt ttattttatg actagcttag ctagcgcaaa
      841 ggtgatttta cttgagctta tcatgatttt atttttatca ggagttctct ttgtttcatt
      901 catgagaatg atgtggtact ccatgtatat ttctcaagga aattatgcag tagatacttt
      961 agaggcgctt tacgaagata tgcaaaaaga caaattagtg catggtaatg tcaataattt
     1021 taaaaactat aatatagaat ttgagaatgt tagctttgct tataatgata aagctgtcat
     1081 tgaaaattta tcctttaatt tagaagaagg aaagtcctac gcacttgtcg gttcatctgg
     1141 atcaggcaaa tcaacagtag caaaacttat atcaggtttt tacaatgtta atgaaggaag
     1201 cataaagata ggcgggatag caataagtga atattctgac gaagccttaa ttaaagccat
     1261 ttcctttgtt tttcaagatt caaaattatt caagaagagc atttatgata atgtagcttt
     1321 agctaataaa gatgcgacga aagatgacgt tatgagagcc ttaaaattag caggatgcga
     1381 tttaatatta gacaaattcc cagaaagaga aaatacaatc ataggctcaa aaggtgttta
     1441 tttatccggt ggagaaaaac aaagaattgc aattgctaga gcaattttaa aggattccaa
     1501 aattattatt atggatgaag catcagcatc tattgaccca gataacgagt ttgaattgca
     1561 aaaagctttt aaaaatctta tgaaggataa aacagttatc atgattgcac acaggctatc
     1621 tacaattaaa gaccttgatg aaattattgt catggatagt ggaaaaatta tagaaagagg
     1681 gtctgacaaa gaattaatgt caaaagatac aaggtataag agcctgcaag agatgtttaa
     1741 cagtgcgaat gaatggaggg tttcaaatga aagagtttta taaaaaaaga tttgctctta
     1801 cagatggagg agcaagaaat ttaagtaaag caacactggc ttcatttttc gtttattgta
     1861 taaacatgct tcctgccata ttacttatga tttttgctca ggaagttttg gaaaatatgg
     1921 gcaaaagcaa tggcttttat atagtattct cagttttgac tttgatagca atgtatattt
     1981 tgctttctat cgaatacgat aaattatata acacaaccta tcaagaaagt gcagatttaa
     2041 gaataaggac agcggagaat ttatcaaaat tacctctatc ttacttttct aaacatgaca
     2101 tttccgacat ttcacaaaca atcatggctg atattgaagg catagagcat gcaatgagcc
     2161 actcaatacc aaaggtgggc ggcatggtac tgtttttccc attaatatct gtaatgatgc
     2221 tagcgggcaa tgtcaagatg ggtttagctg taattattcc atctatttta agctttatat
     2281 ttataccttt atctaaaaaa tatcaggtta atggacagaa tagatattat gatgtcttaa
     2341 gaaaaaactc agaaagcttt caagaaaata tcgaaatgca aatggagatt aaagcatata
     2401 atttatcgaa ggatattaaa gatgacttat ataaaaaaat ggaagatagt gagagagtac
     2461 acttaaaggc ggaagtaact acaattttaa ctttgtctat atcttcaata tttagcttta
     2521 tatctcttgc tgttgtgata tttgtcggcg taaatctaat tattaataaa gagataaatt
     2581 ctctctacct tataggatat ttactagctg ctatgaagat aaaagactct ttagatgcat
     2641 ctaaagaggg cttgatggaa atattttatt tatcgcccaa aatagaaaga ttaaaagaaa
     2701 ttcaaaatca agatttacaa gaaggcgatg actatagctt aaaaaaattt gatattgatc
     2761 taaaagatgt tgagtttgcc tacaataaag acgcaaaagt tttaaatggt gtaagtttta
     2821 aagctaagca gggagaggtc actgctttgg taggtgcaag tggctgcggt aaaacaacta
     2881 tcttgaaact tatatcaaga ctttatgatt atgacaaggg acaaatctta atcgatggca
     2941 aagatataaa agaaatatca acagaatctc tttttgataa ggtctctata gttttccaag
     3001 atgtggttct ctttaatcaa agcgttatgg aaaatattag aatcggaaag caagatgcaa
     3061 gtgacgaaga ggttaaaaga gcagcaaaac ttgcaaattg cacagatttt atagaaaaaa
     3121 tggataaagg tttcgataca gttattggtg agaacggagc tgagctatca ggaggagaaa
     3181 gacaaagatt atcaatagcc agagccttct taaaagatgc gccgatattg atcttagatg
     3241 agataacagc aagccttgat gttaacaacg agaaaaagat tcaagagtct ttaaataatt
     3301 tagttaaaga taaaactgtt gtaatcattt cacatagaat gaaatccata gaaaatgcag
     3361 acaagatagt agttcttcaa aacggaagag tagaaagcga aggtaagcat gaagagcttt
     3421 tacaaaaatc aaaaatttac aaaaatttaa tagaaaagac aaaaatggca gaagaattta
     3481 tttattagga ggactacaat ggataataaa aaattaaaag taaaagattt agtaagtatc
     3541 ggtgtttttg gcgtaattta ttttgccttc atgtttggag ttggtatgat gggcttgatt
     3601 ccaatattgt tcttaatata cccgacagta ttagccatag ttgcaggaac tgttgttatg
     3661 ttatttatgg ctaaggttca aaagccatgg gcactattta tatttggtat gatatcacca
     3721 cttgtgatgt ttgcagctgg tcatacctac atagttgtgg ttttatcact tatagtaatg
     3781 ataatagcag aattaattag aaagattggt aattataatt catttaaata caatatgctt
     3841 tcttatgcaa tcttcagcac atggatatgt agctctttaa tgcaaatgct tttagcaaaa
     3901 gaaaaatata tggagtggtc tttgatgacg atgggaaaag attatgttga tgtattagaa
     3961 aagttaataa cttatcctca catggcttta gtagccttag gtgctttctt aggaggaatt
     4021 cttggagcat atataggcaa ggctctattg aaaaaacact tttcaaatgg attatattgt
     4081 gtgggatact ttactccttg cctaatttta tggtgttatc tgaattaaac cctatagtta
     4141 agatgttttt gagtatacct attgttatta gaatgtttat tttaccattt atggcagcaa
     4201 gctttatgat aaagacctcg gatgtaggcg caataatttc atcgatggat aagcttaaga
     4261 tttcaaagaa tgtatccata cctattgcgg ttatgtttag attcttccca tcttttaagg
     4321 aggagaagaa aaacatcaaa atggctatga gagtaagagg gataaatttt aaaaacccag
     4381 tcaaatatct tgaatatgtt tctgtgccac tactcattat atcatctaat atatcagatg
     4441 acattgcaaa agcggcagaa acaaaggcaa tagaaaatcc aattgccaag accagataca
     4501 ttcgcgtaaa gatacagcta attgattttg tttatgtttt agcggttgct ggacttattg
     4561 tgggaggatt aatatggttg aaataaaaaa tttaagtctt gattatggtg aagagcatat
     4621 attagatgat atatcactat ccatagccga gggagagtgc gtgctattta caggaaaaag
     4681 tggaaatggt aagtcatctt taataaattc aatcaatgga ctagctgtaa ggtatgacaa
     4741 cgcaaagaca aagggcgaaa taattattga tggtaagaat ataaaaaatt tggaacttta
     4801 tcaaatctca atgcttgttt caactgtttt tcaaaatcct aagacatatt tttttaatgt
     4861 caatacgaca ttagaattat tattttattt ggaaaatatc ggtcttgcaa gagaagagat
     4921 ggacaggcgt ttgaaggata tgcttgagat attcccgata aaaaatcttt taaacagaaa
     4981 tatatttaat ctatccggcg gtgaaaaaca aattctttgc attgcagctt cttatatagc
     5041 aggtacaaag attatagtta tggatgagcc ttcatcgaat ttagatatta aaagcataag
     5101 tgttttggca aagatgctaa agatattaaa agagaaaggc ataagcataa ttgttgcaga
     5161 gcatagaatt tattatttga tggacatagt tgaccgtgta tttttaatag ataaaggaaa
     5221 gcttaaaaaa acttatacta gaagtgaatt tttaaagcta gataaaaatg aattaaatgc
     5281 tttaagttta agagataaag aattaagtaa attaaaagtt ccttatttaa aagaaggtgg
     5341 agagtatcag ataaaaaatc ttagctacaa atttactgat gatgagtgtt taagcttaaa
     5401 agatatttcg ttcaagcttg ggaaaattta tggcataata ggatccaacg gacgaggaaa
     5461 atcaacgctt ttaagatgtt taataggtct tgagaaaaaa tcaaaagaag aaatttattt
     5521 taagggagag aagctatcta aaaaagaaag actcaaaaac tcttcacttg ttatgcaaga
     5581 tgtaaatcat caattattca cagatgaagt attcaacgag cttagattag gagtaaagaa
     5641 ttttgatgaa gaaaaggcga aaatcatctt aaaagattta ggcctggacg aatttattga
     5701 aaggcatccg atgagtttat caggagggca aaagcaaagg cttgcaatag catctgttat
     5761 gtgcaagaat tctccatttg tcttttttga cgaaccttca agtggtatgg attattccaa
     5821 tatgataaaa atatctgaac tgattaataa gtataaaacc atggataaaa taatttttat
     5881 tgtttcccat gatatagaat ttttaaatga agtggcagat gaaatttttg aattgtaaaa
     5941 tagagtctgt taaacatgtc tatagaacta gtaaattgtc taaaaattta aaagatacta
     6001 acacatattg atatttatta gaaaattaac ttcaggattt ttacag
//
LOCUS       DBEJKC010000082         6013 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.082, whole genome shotgun sequence.
ACCESSION   DBEJKC010000082 DBEJKC010000000
VERSION     DBEJKC010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6013
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.082"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            152..1921
                     /locus_tag="ACL3G6_001926"
     CDS             152..1921
                     /locus_tag="ACL3G6_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HGR0546398.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     VAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGAFPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            1945..3900
                     /locus_tag="ACL3G6_001927"
     CDS             1945..3900
                     /locus_tag="ACL3G6_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR0546399.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESI
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            3902..4339
                     /locus_tag="ACL3G6_001928"
     CDS             3902..4339
                     /locus_tag="ACL3G6_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0546400.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            4401..5537
                     /locus_tag="ACL3G6_001929"
     CDS             4401..5537
                     /locus_tag="ACL3G6_001929"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HGR0546401.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
BASE COUNT         1832 a         1007 c         1235 g         1939 t
ORIGIN      
        1 gtacacctga tatgatgcgt tttataattt ttaagccttt ttgcccagcc tcgtcaaaag
       61 taatgttttg acacaaaatc tgtgacaaaa ctttagtttt aaaggttttt aactttgtat
      121 atactagttt taagaaaagg aggatgatct aatggaagaa aaagtatcat tgaaggtcag
      181 ggttcaaaaa ctagggacat cgctttcaaa tatggttatg cccaatattg gagcatttat
      241 tgcttgggga gtattgactg ccctctttat cgctgatggc tatctgccaa atgaacagtt
      301 agctactgtt gttggtccta tgttaacgta tttattgcca atcctgattg gttacacagg
      361 tggatatatg atccatggcc aacgtggtgc cgttgtagga gctattgcta ctgttggtgc
      421 aatcacaggt tctagtgttc ctatgtttat cggagctatg gtaatgggcc cactgggagg
      481 atggactatc aagaaatttg atgagaagtt ccaggaaaaa attcgtcccg gatttgaaat
      541 gttagttaat aacttctcag ctggtctcgt tggttttgca ttattgcttt tggctttcta
      601 cgcaatcggt ccagtcgtat cgactcttac tgtagctgtt gggaatggtg ttgaggctat
      661 tgtcaatgct cgcctccttc ctatggctaa tattatcatc gaaccggcta aagtcctttt
      721 tctcaataat gccctcaatc atggcatttt tactcctctg ggagtagaac aggtagctca
      781 agctggtaag tcaattctct tcctattgga agctaatcct ggaccaggcc tgggaattct
      841 attagcttat gctgtattcg gtaaaggttc tgctaaatct tcttcttggg gggcaatggt
      901 tattcatttc ttcggaggga ttcatgaaat ttactttcct tatgttatga tgaagcctac
      961 tctattttta gctgctatgg caggaggtat ctctggaact tttacttttc aactcttaga
     1021 cgctggtctt aaatctccag cttcaccagg ttctattatt gcgattatgg ctacggcgcc
     1081 aaaaggtgtt tggcctcatc taaatgttct tttaggtgtt ttagtggcag cagttgtttc
     1141 tttccttgta gcagccctta ttcttcatgc agacaagtca actgaggatt cgctcgaagc
     1201 tgctcaggcg gctacccaag cagctaaggc tcagtctaaa ggtcagttag tatcaacttc
     1261 tgttgatgca gttgtttcga cagactcagt ggaaaaaatc attttcgcct gcgatgctgg
     1321 tatgggaagc tctgctatgg gagctagtat tcttcgagat aaggttaaaa aagcaggtct
     1381 agagattcca gtatctaatc aggcaatctc aaatttgctt gatacaccaa aaacattaat
     1441 tgttactcag gaagaactga caccaagagc taaagacaag agtccaagtg ctattcatgt
     1501 ttctgttgat aatttcttag cgtcccctcg ttatgatgaa attgtagctt cattaacagg
     1561 agcttttcca atagcagaaa ttgaaggaga tataccaact tcagcaccag tagatagtca
     1621 ggaaattgac cttaaccata ttgatgctgt agtagttgct tatggtaaag cacagggaac
     1681 tgcaactatg ggctgtgaaa cgattcgggc tatctttaga aacaagaata ttcgtattcc
     1741 agtttctact gccaaaattt cagaattagg tgaatttaat tctaaaaaca taatgattgt
     1801 aacaactatt tctttacagg cagaagtgca gcaagcagca ccgaattctc aatttcttat
     1861 tgtggatagt ttagtaacaa caccagaata tgacaaaatg gctgctagaa tgtacaaata
     1921 gaactagagg tttctaaatt acgaatgcta ttaaccaaac gagaagaaca attattgaag
     1981 gctttcctac atgtagggaa gctttcaatg caagatatga ctgaaatctt acaggtttca
     2041 tctagaacaa tttatcgaac tttatcagat ttgacagata gcatggagca atatggaatc
     2101 gaaataacga agcatgggaa atactatatt ttgactggag agttggatga tttgccgaca
     2161 gaacttgaag tgttagttga gtatagtccc caagaaagac aagagttgat tacctatcgc
     2221 cttctgactg agagcggttt tgtcaccaat gaagcattgc aagagtgcac gaaagtcagt
     2281 aatgtaacta ttattcagga tatttcagat attgataagc gtcttttaga ctttgatctg
     2341 aaaattgaac gacaaaaagg ttatcggatt tctggtgatt cagttggtaa gagaagattt
     2401 ttggctattt tactgacaaa ctgtatctca gtagcagatt tttcaaccgg taattttggg
     2461 agctttgata ttttagaagc agatagaact aggctggcca gtcagattgt taataagcaa
     2521 ctgtcaggtt ttccagatat ggatgctagg atgaagatgt tttttgcgat cttgttatct
     2581 cttataggtc aggagcaaaa cattgaaaat tcacctaata ctagtaagca ggctttggaa
     2641 atttctcaaa aaatttttca agcttactct aagcagactg cacaatttta tagtattcag
     2701 gaaattatct attttgcgag catcttggat gaattaatca ttaaacgtca ggacaatccg
     2761 ctctttacgg agaaatttga tggtgaattt ttctacaata tttcaaatct gattgatacg
     2821 gtttccatgt ataccaagat tgactttttt aaggacaagg ttttattcaa ttttcttttc
     2881 catcatattc ggctcagttt aggcgtccct atcctttttc agggtgaaaa tttgccagaa
     2941 tctatccaga ttttagttga aaggaataaa tttctttata cagtcatcag tcttttagtg
     3001 aatgatattt ttccgaaata tcttcataca gagtatgagt atggcatgat tgccctacat
     3061 tttatctcta gcttaggccg tagtccagag atttatccag tccgtgtttt gcttttaacg
     3121 gatgaacgtc gggtcactag agatttatta gtcagtaaaa ttaagagtgt tgctcctttt
     3181 gtagagttga tagatattca gtctctagta gattaccaca gtattgatct cagtcagtat
     3241 gattatattt tatctaccaa gccgctgact aatcaggaaa tcgatgtaat ttctagtttt
     3301 ccaaccgtca aagaattgct tgaattacag gaacgacttc agtatgtaca ggcacatcgt
     3361 acaattgtcg cgcgtgatgc tatcgctcca gagaaaagtt atgacttgca agattattta
     3421 atatctagta gtcagctttt gagtcaattt gagttggttc aattggagaa taatcaatca
     3481 tttgagcaca cggtagaaca aatcatccaa tatcagaaga atgtgagtga cagagattac
     3541 ctaacaagaa aattgttatc tcacttccag aatagtccta tggctattcc taatactggt
     3601 ctggtgcttt tacatagtca gtctagcaaa gtaacaacaa atagttttac tatgtttgaa
     3661 ctcaaactac ctatctccgc attgtcaatg aaacgagagg aagaagaggt caaaaggtgt
     3721 ctgctaatgc taatgtctaa agaagctagc gaggaagcga gagatttaat gacagctatt
     3781 agtcagtcga ttattgaaaa tcatctttat acagagattt acaagacggg aaatcaatcc
     3841 attatttatc agatgctaaa tactattttt aacgaaaaaa ttaagaaatt ggagaactaa
     3901 tatgaaactt gaaaaacatt tgattaagct taataaacaa ttttctaaca aggaggaagc
     3961 tatttgttat tgtgggcaag ttctttatga gggtggatat gttaatgaag actatattga
     4021 agccatgatt gagcgagata aagagctatc tgtttacatg ggtaacttta tcgccatacc
     4081 gcatggaaca gatgcagcaa aaaaggatgt actcaagtct ggtattacag tcgttcaagt
     4141 ccctagaggg gttgattttg ggaatgtatc taaccctcaa gtggcaacgg ttctttttgg
     4201 tattgctggt attggtaatg aacacttgga aattattcag aaaatttcta tcttctgtgc
     4261 agatgtagat aatgttctta aactagcaga tgctcagtca aaagaggaag tattgcgctt
     4321 atttgatgct gttgaataat tgaatttcgt catttgtcat ctagtatata tgtccctcaa
     4381 ataggaaaag gagaaattga atgaaacatt ctgttcattt tggtgccggt aatatcggtc
     4441 gtggttttat aggtgaaatt ctatttaaaa atggtttcca tattgatttt gtggatgtca
     4501 ataatcagat aattcatgct ctaaatgaaa agggcaagta tgaaattgaa attgcacaga
     4561 aaggacagtc tcgtatagaa gtaactaatg tggctggcat taatagcaaa gaacatcctg
     4621 agcaagtcat tgaagcgatt caaaagacgg atattattac tactgcaatc ggacctaata
     4681 tactcccttt tatcgccgaa cttctagcca aaggaatcga agctcgccga gttgcaggaa
     4741 atacacaggc attggatgtt atggcctgtg aaaatatgat tggcgggtct caatttcttt
     4801 atcaagaagt caagaaatat ttaagtccgg aaggtttgac atttgctgat aactacatag
     4861 gttttccaaa tgctgcagta gacaggattg ttccagcaca aagtcacgaa gattcccttt
     4921 ttgttgtggt cgagcccttt aatgaatggg tcgtggaaac caagcgtctt aaaaatccag
     4981 atttacgtct aaaagatgtg cattatgaag aagatttaga accctttatt gagcgaaaac
     5041 ttttttcagt caattctgga catgcaactt cagcttacat tggtgcgcat tatggtgcca
     5101 agacaatttt ggaagctctt caaaatccta atattaaatc tcggattgaa tctgtattag
     5161 ctgaaattcg gagtctcttg attgccaaat ggaactttga taaaaaagaa ttggagaatt
     5221 atcacaaagt cattatagaa cggtttgaaa accctttcat agtggacgag gttagtcgcg
     5281 tagctcgtac tccaatccga aaattaggct ataatgaacg attcatccgg ccgatacgtg
     5341 aattgaaaga actcagtttg tcatataaaa acctacttaa aacagttggc tatgcctttg
     5401 actatcgcga tgtaaatgat gaagaaagta ttcgattagg tgaattgttg gctaaacaat
     5461 cagtcaaaga tgttgttata caagttacag gtttagacga ccaagaattg attgagcaaa
     5521 ttgtagagta tatttaatct ttttcgaaaa tctcttcaaa tcaggttagc atcgctttgt
     5581 cttaggcata tgttgttcta tctacaacct caaagcagtg ctttgagctg actccgtcag
     5641 tcttgtctgc aacctcaaaa cactgtttga gttatctgcg gtaatctttc tagcttgtct
     5701 ttgatttttg ttgttattta taaggtaaaa gaagctggac aaaaagtctt caaaatcgga
     5761 aaaaggcagc ctatcgggtg ttcaaaaatc ttgataggat gtcctttatt atggaaagcc
     5821 ttattggatt ttctcctcag attgagtttt tgatcagctt tatgagatag gttttgctag
     5881 agatgtagcc catcatgtta tttttatgga cggtgggaaa attgttgaaa aaaataatgc
     5941 ccatcaattc tttagtcgtc caagagaaga acgaaccaag caattttgga acgaattctt
     6001 tcgaatgcga tct
//
LOCUS       DBEJKC010000083         5529 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.083, whole genome shotgun sequence.
ACCESSION   DBEJKC010000083 DBEJKC010000000
VERSION     DBEJKC010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5529
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.083"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(177..452)
                     /locus_tag="ACL3G6_001930"
     CDS             complement(177..452)
                     /locus_tag="ACL3G6_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HGR0546402.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(558..1397)
                     /locus_tag="ACL3G6_001931"
     CDS             complement(558..1397)
                     /locus_tag="ACL3G6_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR0546403.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1539..2387
                     /locus_tag="ACL3G6_001932"
     CDS             1539..2387
                     /locus_tag="ACL3G6_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGR0546404.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFIFGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2480..3397)
                     /locus_tag="ACL3G6_001933"
     CDS             complement(2480..3397)
                     /locus_tag="ACL3G6_001933"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HGR0546405.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3874..4022
                     /locus_tag="ACL3G6_001934"
                     /pseudo
     CDS             3874..4022
                     /locus_tag="ACL3G6_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
     gene            4371..5529
                     /locus_tag="ACL3G6_001935"
                     /pseudo
     CDS             4371..5529
                     /locus_tag="ACL3G6_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1744 a         1105 c          895 g         1785 t
ORIGIN      
        1 aaattaattt ctataaatgt tttagcaatt gtttcgtact attttagatt cagtctacta
       61 tgtacaatat tttcggaaca ttcaactttt taactctatt tattactaga tttcataatt
      121 aaaaagccta ctgaccaagc tagaaagctt gatacaatag gctttttaaa gactgattat
      181 ttaacagcgt ctttaagagc tttaccagct ttgaatgctg gtactttaga agctgcaatt
      241 gtcatttctt taccagtttg tgggttgcga cctttacgtt ctgcacgctc acgaacttca
      301 aagttaccaa aaccgatcaa ttgaactttt tcaccagctg caagatagtc agctactgct
      361 gcaaatacag cttcaactgc tgctgctgag tctttcttag tcaattctgt agcttctgct
      421 actttagcga tcaaatcttg tttgtttgcc atgttaatga ttcctccaga taatttctaa
      481 ttaacaaata taatcatatc ctaaaatccc ttttaggtca agttaaaaac gctatttctt
      541 ccaattttat ttatttttta ggagtggtaa cgtatcaaaa tagcccaagc gttctcaccc
      601 gtgtgagttt gaataatgga acccgtttcc aaaacagaaa ttggcttttc aacataagct
      661 tgtaagcttt ctttcatctc ttttgcccaa tcatcactac cagaatatga aattccaatc
      721 tctgctacag cacgttcaga aagcgatgtt atcaactcat ctaaccattt tttaaatgtt
      781 ttagttccac gacctttaac cattggctgc aattcatggt ctttcatttg catgacaaca
      841 cggatattga gaagggagct caacaagcca gttacacggc caattcgtcc acctttgaca
      901 agattttcca aagttgaaac accaatataa agctctgtat ggtttttaac ctcttctaca
      961 tgagataaaa ttgcctccat atctttacct tcttgagcta acttcgcagc ctcaacaact
     1021 tggaatttca gggcttggtc agtgaaggaa ctatcaacaa cagtcacatc tgcagtagat
     1081 aggctagcac cttggcgtgc tgcttctacc gtacccgaaa gagcatggga catatgaata
     1141 gcaagaatct ggccaccatc tttgcatagg tcttcaaaaa tctcagcaaa gacacctaca
     1201 ggtggctgac ttgttttcgg aagattctta ctttcttgca tcaactgaag aaatttacct
     1261 tcttctttca aatccgcatc agaataaaca acattatcaa tcattacaga taatggaaca
     1321 attgtaatat ctaattgctt tactagttca ggttcaatag taacagatga atcggttaca
     1381 atcttaattt ttgtcatagt atcaatcttt ctattttagg attcagattg gtttccttac
     1441 ttctaattat atcaaaaaaa agattaaaaa tcctaatgga gtcaatcaaa ttttccgtaa
     1501 aatttgatat aatcaactta taagaaaaga ggtgtcctat gattaaaaaa atttacccca
     1561 tttttaccat tttactaggt gctgctattt atgcttttgg actgacttat tttgtagttc
     1621 cccatcatct ctttgaagga ggggcgacag gcattaccct catcaccttt tatcttttta
     1681 aaatccctgt ttccctcatg aacctgctga ttaatattcc ccttttcatc ctagcttgga
     1741 agatctttgg agccaaatcc ctctattcta gtttactagg aaccttagct ttgtccgcct
     1801 ggttagcttt ttttgagcat attccccttc atattgatct tcaaggtgat ttactaatca
     1861 cagcccttat agcgggaatc ctattgggaa ttggccttgg aattattttt aatgctggag
     1921 gtacaactgg cggaactgat attctagctc gtattctcaa caaatacact catatatcca
     1981 taggaaaact gctctttatc ttagattttt gtattctcat gttgattctc ctaatcttca
     2041 aggatttgag attggtttcc tacacgcttt tgtttgattt tattgtttct cgtgttattg
     2101 atttgattgg tgaaggagga tatgccggca aaggctttat gattatcaca aaacgtcctg
     2161 accaacttgc taaggcgatt aatgatgacc tcggaagagg tgttactttt atttttggtc
     2221 aaggctacta tagtaaagaa aatttgaaaa tcatctactg tattgtcgga agaaatgaaa
     2281 ttgtgaaaac gaaggaaatg attcatcgaa tcgatcctca agcctttata actattacag
     2341 aagcccatga aatcctagga gaaggcttca cctttgaaaa agaataaaaa gaggtaatgt
     2401 cgtgacctca aaagttagac taaatcatct atcttttggg ttacagacaa cctctttttt
     2461 gttttattta ctcaagctct taagaccaat tccgagttac ttcttcatca gcctttaact
     2521 gatccactaa ttggtcaact gagtcaaatt tggtcatatc acgaatgcga tcaagccaat
     2581 aaaccatgac ggtttcccca taaatatctt gattaaaatc aaaaatattg acttcaaaac
     2641 gtgcttcttc tccatcaaag gtcacatttt tcccgacact agccatagca cgatacttct
     2701 gtctttgaat ctcaacatca acgacataaa cgccatctgc tggcatataa gtacggtcta
     2761 aaagcactaa attcgctgtc ggataaccaa ttgtacgacc acgagcatta ccatgaacta
     2821 ccatacctct tgatggaagc ggtgccccca aaagttttcc tgcttctttc acatttccat
     2881 ctaaaatagc ttgacggata cgagttgaac taatctttcc tttctcatct tctacaggtg
     2941 gaacaatgat aacttctcca tcaaagtaat cctttaaatc ttctgctgtt tttttgtcag
     3001 aaccaaatgt ataatcaaaa cctgcaacaa taattttggc attcatagcc ttgatataag
     3061 ttgcaaagaa ttcttgtgca gtgagactag cgaattgact actaaaatca aggagatata
     3121 attcttctac accttcgcgc tttagttttc tttcacgttc agcagggttc aaaatatgca
     3181 aaaacaaatc tggatgataa ggctctaaag cgatctttgg agattcatta aaggtcataa
     3241 cgacgatagg taataaatcc tttctcgcag ccttgttggc aacacgaaat aattcttgat
     3301 gccccttatg tatgccatca aaatagccga gaacaacgac tgaatcagat ggtgtgccaa
     3361 tatctttttg gttttttata ggaatagtaa taatcataaa ataattatat catagcgata
     3421 gctatttctg gaacagaaaa tctgaaatgt tgtttttttc acatgaagtg tacctgtttt
     3481 caaaaagcac tttattctat cgttgcttaa ctatgaactt tgcaatattc ttctcaaaaa
     3541 cttgtaggac atcttcaaaa ttttgcaagg agtgattaga cttgttcggt aaccataaag
     3601 tgtcatacta tgcttatgta tgaaaaagca atgcaactaa ctcctgagaa ctttaaatta
     3661 ctaattggtg ccgaaaaggt agaatttaga atcgaggtac acctatggct gtaaaattta
     3721 caaaatgaga caacttgggc aagatgtttg aagaatttcc taaactccct gatttgaagc
     3781 aagtcacttt ccctgatgac aaaaaaagcc aaagcagtaa agaaaaacta gatgactgct
     3841 ttccaacaac ttccatctag tgtgcttcag actgggctat ttttctctcc atctgttagc
     3901 ttggattctc agaccgtttc agctaaagaa tatcttttcc cttatcagaa ggaacggctc
     3961 aagccattca gacaagtgaa gggacgacaa gccaatattt gaaaccagat agcagttctt
     4021 atagtcaatt gaaataaaat ctgaagaaat cgagtaggaa actcaaatca atttttaaca
     4081 gtgttctatt ccagattcat actcaatgaa aattaaagtg caaactagga agttagccgc
     4141 aggctgtact tgagtacggc aaggtgaaac tgacgtggtt tgaatttgat tttcgaagag
     4201 tatcaatcca ctatacatat taaaaagtat gggtatcaaa ataaaaaggc tctataatat
     4261 ttgtagtggg taaatccact atagatatta tggagcctat tttgtgtaga aaaaaagtcc
     4321 catatgacct ataatgaaaa gcgatcaaac aactcattag aaagattcat atggaacaat
     4381 tacattttat cacaaaatta ctagacatta aagaccctaa tatccagatt ttagacatca
     4441 tcaataagga tacacacaag gaaatcatcg ccaaactgga ctacgacgcc ccatcttgcc
     4501 ctgagtgcgg aaatcaattg aagaaatatg actttcaaaa accttctaaa attccttatc
     4561 ttgaaacgac tggtatgcct actagaattc tccttagaaa gcgtcgtttc aagtgctatc
     4621 actgttcaag aatgatggtc gctgaaactt ctatcgtcaa gaagaatcac caaattcctc
     4681 gtattatcaa ccaaaaaatt gcgcaaaagt tgattgagaa gatttctatg accgacattg
     4741 atcatcagtt gtctatttca acttcaactg tcattcgcaa gatcaatgat tttcacttta
     4801 aacatgattt ttcttgtctt cctgagatta tgtcttggga tgagtatgcc ttcactaagg
     4861 gaaagatgag tttcattgcg caagattttg ataatcttaa tattatcact gttcttgaag
     4921 gcagaacaca agctgtcatc cgaaatcact ttcttcgcta cgatagagcc gttcgttgtc
     4981 aagtgaaaat cattacgatg gatatgttta gtccttacta tgacttggct aaacagcttc
     5041 gctttcaaat ttctaggctc aggctgaaac agtctcccag actgtttcac tcccgaatgc
     5101 taaaatcgtt cttgatcgct ttcacattgt gcaacatctt agccgtgcta tgagtcgtgt
     5161 gcgtgttcaa atcatgaatc agtttcatcg aaaatcccat gaatacaagg ctatcaagcg
     5221 ctactggaaa ctcattcaac aggatagccg taaactgagt gataaacgtt tttatcgtcc
     5281 tacttttcgc atacacttaa caaataaaga aattcttgac aagattttaa gctattcaga
     5341 agacttgaaa caccactatc agatctatca actcttactt tttcactttc agaacaaaga
     5401 ccctgagaaa tttttcggac tcattgagga caatctgaag caggttcatc ctatttttca
     5461 gactgtcttt aaaacctttc taaagaacaa agaaaaaatc gtcaacgctc ttcaattacc
     5521 ttattccaa
//
LOCUS       DBEJKC010000084         5283 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.084, whole genome shotgun sequence.
ACCESSION   DBEJKC010000084 DBEJKC010000000
VERSION     DBEJKC010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5283
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.084"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..2367
                     /gene="lanM"
                     /locus_tag="ACL3G6_001936"
     CDS             <1..2367
                     /gene="lanM"
                     /locus_tag="ACL3G6_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="HGR0546406.1"
                     /translation="WIDKNGNIFSSLVFYLEDLIYPWIVKPLVLEINSLREKGLLEGE
                     SEQQRYKYFITLFDKEENILNFYNKYPVLLRQISESCLRFYTYFIEILSNLENDFSVL
                     EEELGLRGKLNDIKFGKGDTHSQGKTVLILFFDDAKIVYKPKNLIINNSLNTIAEYIR
                     KVDEKIRIRIPRTIAYSDHSYEEFIDYLPLEQKKKLPEYYYNFGVLLAFIYLFNGSDI
                     HFENLISYGDMPVIIDFETMLQQPLFDDKTGQSLLDTLFHRVTRTLLLPTEGVKREDG
                     LDVEMSALTGNFKKDAFNGQVLINLNTDKVKFDIGKIDFEGGKNLPVRDGDIEFDKYI
                     KDFKKGFRDFYLIFEELNKTEEFKMLLKANLYGLKTRVLFRDTNSYASVLSFLYHPDF
                     YEEMLDREKALENLWSNKFSNQGIVASECEQMRLLDIPIFYTDTNINEIYDDFGNHFI
                     SLHQFSGYDYFMKYLPNNNLENLEKQLDIIEIYFPSFDQRKKGYKLNLSNRKKLPNES
                     LVTILHNEVENIADSLVINNIYDEYPIWSIPVNFKGSKWCLEQTGNDMYRGRAGILLF
                     MYYVKLLKDKSSYTQLYNKMLSAIPPSVSLSKTTFGLTGDIGYFIVLSIIEDYDTNTL
                     ACLNYIKSVLTELEKTDFASVSNKSDYINGLLPLINTLVRYYRRGIEKERVLRLVLSL
                     GDTLYNDVSERDNSNFGYSFGHGSMAIINFYIDYMKEMDTSMELESLLCSVVMNKSKE
                     GEYRIVQTSNFPDFSLYTGVTGIAYTFLRYIALNQNDKKIVIPSLLEI"
     gene            2717..3421
                     /locus_tag="ACL3G6_001937"
     CDS             2717..3421
                     /locus_tag="ACL3G6_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HGR0546407.1"
                     /translation="MNKIFIYAGVRNHNSKTLEYTKRLSSIISSRNNVDISFRTPFNS
                     ELEISNSDSEELFKKGIDRQSNADDGGVIKKELLESDIIIISSPVYLQNVSVDTKNFI
                     ERIGGWSHLFRLAGKFVVTLDVAESNGSDNVSEYLRDIFSYMGGQILHQVSITNSLKD
                     IAEAQLMEATYKIEDVLEGKIKYKTTDYQERAYQTLKLILENYDSEHFEKMYWEKKRL
                     FEANSLEEWYYVENIK"
     gene            3402..4331
                     /locus_tag="ACL3G6_001938"
     CDS             3402..4331
                     /locus_tag="ACL3G6_001938"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HGR0546408.1"
                     /translation="MLKILNNSVIYLCLIPLLFLLLIIFPNDSLIYYFRLILISLISI
                     TLHELGHFLVGRCLSYKLEMLATPFFFYFRKKIYFKFPVLLAFGYCQMSNRNITNEKN
                     SDRNLVFYFFGGGGANLIVAILALLGFVPYASEFFILNIILFLVTVCLPIDGTDGNAI
                     REIVLYSKDSKTYQRFFANSLYNNPYITIDDFAKLTSKEKSFFSKFEKCLINLYFEVK
                     GEGSAFTIANHEVFDSNIQENIIHEYYKLLHKSSDWIIPQNLSLEEVVFTLSNYIYSK
                     NNKYLEKIKYLKKLVDFRQEEIIDFILNKEEVL"
     gene            4328..>5283
                     /locus_tag="ACL3G6_001939"
     CDS             4328..>5283
                     /locus_tag="ACL3G6_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="HGR0546409.1"
                     /translation="MKIPMIYQMENSECGLACCAMILNYFKYEISLNELREIYPSSRS
                     GYSLLSISKVLGDFNISSHAFKASVRDLKPLSFPLICFWESSHFIILEKISKNKFYIL
                     DPAKGRQRMSISEFERHYSNIILTFKKLDSFMSRKDNKKSPVLKYFFKYRNKLGILFF
                     VTALLYVIQSLVPIANRYIIDTNFKDDSYSSRMLFTILFIFTVSFSLMYLLRQIYVAS
                     LKYIMDKEISYDFMKHLIYLPYSFYEKRTLGDILFRANSIVYIREILSNNFIAAILDL
                     LMIVVYAVVLFSFSKYMVIFLISLSLALSIVMYPIIKISKNL"
BASE COUNT         1879 a          627 c          895 g         1882 t
ORIGIN      
        1 tggattgaca agaatggaaa tattttttcc tctctagtat tttatttaga agatttaatc
       61 tatccttgga ttgttaaacc tttggtttta gagataaatt cattgcgtga aaaaggttta
      121 cttgaagggg aatcggagca gcaacggtac aaatatttta taacattgtt tgacaaggaa
      181 gagaatatat taaattttta taacaaatat cccgttttac tgaggcaaat atcggagtct
      241 tgtcttcggt tctatactta ttttatagaa attttatcaa atttagaaaa tgattttagt
      301 gtgctagaag aagaattagg gctaaggggg aaattaaatg atataaaatt tggaaagggt
      361 gatacacaca gccaaggaaa aactgttttg atactcttct ttgatgacgc gaaaattgtt
      421 tacaagccta aaaatttaat aatcaataac tcactaaata ctattgctga gtatatccga
      481 aaggttgatg aaaaaattag gataagaata cctcgaacta ttgcttattc ggatcacagc
      541 tatgaagaat ttattgatta tctacctcta gagcaaaaga aaaaattacc tgaatattat
      601 tataattttg gtgtgctttt agcatttata tatttattta atgggagtga tatacatttt
      661 gaaaatttaa tttcctatgg agatatgcct gtaataatag actttgaaac aatgttacag
      721 caacctctat ttgatgataa aactggtcag agtttgctgg ataccctgtt tcacagggtg
      781 actcgaactt tgcttcttcc aacagaggga gtaaaaaggg aggatggtct tgatgttgag
      841 atgagtgctc ttacaggaaa ttttaagaag gatgctttta atggtcaagt tttaattaat
      901 ttaaatactg ataaggtaaa gtttgatatt gggaaaattg attttgaagg tgggaaaaac
      961 ctgcctgttc gggatggtga tatagaattt gataagtata taaaagattt caaaaaaggt
     1021 tttagggatt tttatctgat atttgaagag ttaaataaaa cagaagaatt taaaatgcta
     1081 ttaaaagcaa acttgtatgg tttaaagaca agggtacttt ttagagacac aaatagctat
     1141 gcttcagtac tatctttttt atatcatcct gatttttatg aagaaatgtt agatagagaa
     1201 aaagcattgg aaaatctctg gagcaataag ttttctaatc aaggtattgt agcaagcgaa
     1261 tgtgaacaaa tgaggttatt agatattccg attttttata cagatacaaa tatcaatgaa
     1321 atctacgatg attttggaaa tcattttatt tccctacatc aattttctgg atatgactat
     1381 tttatgaaat atttacctaa taataatttg gaaaatttag aaaagcaact tgatatcatt
     1441 gaaatttatt ttccaagctt tgatcagcga aaaaaaggat ataaattaaa cttatctaat
     1501 agaaaaaaac tcccaaatga aagtttagtt actattctgc ataatgaagt agaaaatatt
     1561 gcagactctt tggttattaa taatatttat gacgaatatc caatttggag tatacctgtt
     1621 aattttaaag gttctaaatg gtgtcttgaa caaacgggta atgatatgta taggggtaga
     1681 gctggaatat tactgtttat gtactatgta aaattattga aagataaatc atcatatact
     1741 caactgtaca ataaaatgtt atctgcaatt ccgccatctg tttctttatc taagaccaca
     1801 tttggtttaa ctggggatat aggatatttc attgttctat ccattataga ggattacgat
     1861 acaaatactc tcgcatgctt aaattatata aagagtgttt taactgagct tgaaaagact
     1921 gattttgcaa gtgtttcaaa caagtctgac tatattaatg gtcttctacc tttaattaat
     1981 acactggtaa gatattatag gagaggaata gagaaggaac gtgttctaag gctagtatta
     2041 agtttaggtg atacgctata taatgatgta agcgagagag ataatagtaa ttttggatat
     2101 agttttggcc atggaagtat ggccataata aatttttaca tcgactacat gaaagaaatg
     2161 gatactagta tggaattgga gtctttattg tgtagtgttg taatgaataa atcaaaagaa
     2221 ggagagtatc gtatcgtcca aacaagcaat ttcccagatt tttctttgta tacaggtgtg
     2281 actggtattg cttatacttt tttaaggtat atcgcactga atcagaatga caaaaagata
     2341 gttatcccct cattacttga aatctagctt aatttatagt tttgtttcta aaatagaggt
     2401 gtccactcat taagcaatat aaaaatacca agattgacta gtttaatatg taattctata
     2461 aaatattttt aatagtgtag cttttcgttg agataataat ataataaaga aaggttctat
     2521 tctaattgct aaacggcttg aggtatatgc tactgttata gaaatgattt taaactaaaa
     2581 tcaaaattac tccaaaaata gtattgattt tggtttaata caaaacatat gtaataatgt
     2641 gagtcaacaa aagtctgttt ttgtaccata ctatcttgaa aaatctacta aattcaaatt
     2701 gagaggatga attaaaatga ataaaatatt tatatatgca ggagtgcgaa atcataactc
     2761 taagacttta gagtatacta agagactttc aagtatcatt tctagtagaa ataatgttga
     2821 tatatctttc aggacacctt tcaattcaga gctagaaata tctaattctg attcagaaga
     2881 gttgtttaag aaaggaattg ataggcaaag taatgctgat gatggaggtg ttataaaaaa
     2941 agagttatta gagtctgata ttataattat ctcttctcct gtatatttac aaaacgtatc
     3001 tgtggacaca aaaaacttta ttgaaaggat tggggggtgg agccatcttt ttcgattagc
     3061 tggaaagttt gttgtaacat tagatgttgc tgagagtaac ggctctgata atgtgtcaga
     3121 atatcttaga gatatatttt catatatggg aggacagata ttacaccaag tttcaattac
     3181 caattcactc aaagatattg cagaggctca gttgatggag gcaacttata aaattgaaga
     3241 tgtacttgaa gggaaaatta agtacaaaac aacggattat caagaaagag cttaccagac
     3301 attaaaatta attttagaaa attatgattc cgaacatttt gagaagatgt attgggagaa
     3361 aaaacgcctt tttgaagcta atagtttaga ggaatggtat tatgttgaaa atattaaata
     3421 actctgtcat atatttatgt ttgattccgt tattgttcct attattgata atttttccaa
     3481 atgattcatt aatctattat tttcgattga ttttaatttc gttaatatca attacattac
     3541 atgaactagg tcatttttta gtgggaagat gtttatctta taaactagag atgcttgcta
     3601 ctcccttttt cttctatttc agaaaaaaaa tatatttcaa atttccagtg ttattagcat
     3661 tcggttattg tcaaatgagt aatagaaaca ttactaatga aaaaaatagt gataggaatt
     3721 tggtgttcta cttctttggg ggaggtggag ctaacctaat tgtcgcaata ttagcacttt
     3781 tgggatttgt gccgtacgca tcagaatttt ttattttgaa tataattctt tttctagtta
     3841 cggtatgttt accaattgat ggaacagatg gcaatgctat tagagagata gttttgtatt
     3901 caaaagattc aaaaacatat cagagattct ttgcgaacag tctctataat aatccttata
     3961 taacaatcga cgattttgca aaattaacct ctaaagaaaa atcttttttt tcaaaatttg
     4021 aaaaatgttt gataaacctt tactttgaag tgaaaggtga agggtcagca tttacaattg
     4081 ctaatcatga agtttttgat tcaaatattc aggaaaatat tatccatgag tactataaat
     4141 tactacataa atcttctgat tggattattc cacagaactt atctttagaa gaagttgttt
     4201 ttaccttgtc aaactatatt tactcgaaaa ataataaata tttagaaaag attaagtatc
     4261 taaagaaatt agtagatttt agacaagaag aaattatcga ctttattttg aacaaggagg
     4321 aagtattgtg aaaattccaa tgatatatca aatggaaaat tcagaatgtg gattagcatg
     4381 ctgtgccatg atattgaact attttaaata tgagatttct ttaaatgaac tacgtgaaat
     4441 ctacccatca tccagatctg gatattctct cctatctata agtaaagttt taggagattt
     4501 taatataagt tctcatgctt ttaaagcttc ggtaagagat ttaaaaccgc tcagtttccc
     4561 actcatttgc ttctgggaga gttctcattt tattattctt gaaaaaatta gtaaaaacaa
     4621 gttttatatt ttagatcctg caaaaggcag gcagagaatg tcaataagtg aatttgaaag
     4681 gcattattca aatatcattt taacatttaa aaagttagat agctttatgt ctcgtaaaga
     4741 taataagaag tcgcctgttt taaagtattt ttttaagtat aggaataagc tagggatttt
     4801 attttttgta acagcattat tgtatgtaat acaatcatta gtacctatag ctaatagata
     4861 cataattgac acgaatttca aggacgattc gtattcgtct agaatgttat ttactatatt
     4921 atttatattt actgtttcat tctcactaat gtatttatta agacagatat atgttgcatc
     4981 cttaaaatat ataatggata aagagattag ctatgatttt atgaaacatt tgatatattt
     5041 accttacagt ttttatgaaa aacgtacttt aggggatata ctttttagag ctaactctat
     5101 tgtttatata agagaaatac tatcaaataa ttttatagca gctatacttg atttgttaat
     5161 gattgtggtt tatgctgtgg ttttatttag cttttctaag tacatggtaa tctttttaat
     5221 atcactaagt ctagctctat ctattgtaat gtatccaatc ataaaaatct caaaaaattt
     5281 aat
//
LOCUS       DBEJKC010000085         5213 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.085, whole genome shotgun sequence.
ACCESSION   DBEJKC010000085 DBEJKC010000000
VERSION     DBEJKC010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5213
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.085"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(361..1089)
                     /locus_tag="ACL3G6_001940"
     CDS             complement(361..1089)
                     /locus_tag="ACL3G6_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0546410.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1247..2656
                     /locus_tag="ACL3G6_001941"
     CDS             1247..2656
                     /locus_tag="ACL3G6_001941"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGR0546411.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2674..3969
                     /locus_tag="ACL3G6_001942"
     CDS             2674..3969
                     /locus_tag="ACL3G6_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0546412.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLALVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            3974..4282
                     /locus_tag="ACL3G6_001943"
     CDS             3974..4282
                     /locus_tag="ACL3G6_001943"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0546413.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4279..4587
                     /locus_tag="ACL3G6_001944"
     CDS             4279..4587
                     /locus_tag="ACL3G6_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0546414.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1755 a          879 c          948 g         1631 t
ORIGIN      
        1 ttgggagatt gaaattcatt tctagcaatt ttttagaagt cacagtctac tattctaacc
       61 tcagtatact atatgtgtta caagaaaaga ctcaaaaact tctcgtcagt gtaagaatgt
      121 ttgaaacact atttaaaact aaataactat aagaagtaga tcaggtgaac aatttcagta
      181 cctactctat aagctatacg aagatatttt tcaacatgat ggataaaacg atcactcttt
      241 taaagctatc ttatttagaa aagagaaacc atttaagcat agatgggacc ttcttgccct
      301 gttttaaatt tttcttaaac tagagtctgt aaaagattgg cttcattttc acattttctc
      361 ctaggaggaa tgtcgtaatg caaaagaatt aaattcaaat aaatcatagc gatgacgact
      421 aatcgagtac tcaaacggag ttccgttatc caaataagcc acttgttcta cttcaaatac
      481 cggttccgtt ggaaggagct gcaagtaatg ttgctcattt tctgaactag aagaagctcg
      541 caagattttt gtagcactgg caatatgcaa tcctaacttt ccttcaatgt aattgtaaat
      601 cgatttttgt aaaatatctt cagtaatacc tggaataaca tcggtactca tataagtttg
      661 ttccagaaca taaggtttac cgtcaataat acgcagacgg taaatattat aaactggact
      721 ctgcaaagcg acctgtagtt tttctgctaa aaattcattt gcaaattcta atttgaagtg
      781 aataatcctc gagtcaattg tagaatgagc atcttcagat atttttgtca gtccccggat
      841 atctctttct ggaacgatta attttctttt tgagctgcca cgagagagaa caaaggttcc
      901 ctgcccacgt tttctaaaaa ttaagccctc agaaactaac aagtctaaag cttttttgat
      961 cgtcattcga ctacaggcaa actgtttagc taatgtcatt tcatcaggca attgttcgtt
     1021 catggtatat ttattacaaa gaatcttttc acgaatctca ttgtaaataa ataaatattt
     1081 tgtactcatt taatctggtt ctctctataa tattctaata gtagtataac aaagttcaag
     1141 aaatgaggca aacacaagac atgtatcaac aatttttaaa aatgtctaga caaattttaa
     1201 aattatgcta tactttatgt atagaataat agaaaggagg ttgagcatga aaaaaaagtt
     1261 agtatttcct aatctgtttt ggtggggagc tgcttctagc ggacctcaga cagaaggtca
     1321 atatggaaaa gtacatgaaa atgtgatgga ctactggttc aaaacgcatc cagaagattt
     1381 tttcgataat gtcggacctc ttgtagccag taactttttt catacttaca ccgaagattt
     1441 ccacttgatg aaggaaattg gagttaattc tttccgcact tccatccaat ggagtcgact
     1501 catcaagaat ttagagacag gtgagcctga tccaaaaggt attgctttct acaatgccat
     1561 cattgaagaa gctaaaaaga accagatgga tcttgtgatg aatttacatc attttgattt
     1621 accagtggaa cttcttcaaa aatacggtgg ttgggaaagc aaacatgtag tggagttatt
     1681 cgtgaagttt gccaagactg ctttcacatg ctttggagat aaggttcatt actggacaac
     1741 tttcaatgag ccaatggtca ttccagaagc aggatactta tatgctttcc attatccaaa
     1801 tctaaaagga aagggaaaag aggccgtaca agtcatctat aatctaaacc ttgctagtgc
     1861 aaaagtgatt caactatatc gctcattagg acttgatgga aagattggga ttattttaaa
     1921 cttgacacct gcttatccaa gaagtaattc tccagaagac ttagaagcaa gtcgatttac
     1981 agaagacttc tttaacaaag tcttcttgaa tccagctgtt aaaggaactt tcccagaaag
     2041 attggtaaaa cagctagaga gagatggcgt gttatggagt cataccgaaa aagagcttca
     2101 actgatgaaa tcaaatacgg ttgattttct tggagtaaac tactaccatc caaaacgtgt
     2161 tcaagcacaa gcaaatcctg aggaatatca gacgccctgg atgccagacc aatacttcaa
     2221 agagtatgaa tggccggagc gtcgcatgaa tccatatcgt ggttgggaaa tttttccgaa
     2281 agccatttat gatattgcta tgattgtgaa ggaagaatat gataatattc catggtttat
     2341 cagtgaaaac ggaatgggtg ttgaaaacga agcacggttt atcgatgaaa atggagttat
     2401 cgatgacgtg tatcgtattg aattttatga agaacattta agatggctac ataaagccat
     2461 tgaagaggga agtcactgtt ttggatacca cgcttggacc gcatttgatt gctggtcttg
     2521 gaataatgca tataagaatc gttacggatt tatctccgtt gatttagaaa cgcaaaagag
     2581 aaccatcaag agctcaggaa gatggtatcg caaagtaagt gacaataacg gttttgaagt
     2641 agaaattgag gagtaaagag aggagatatt cagatgaaaa actcaaaatt tatagatcaa
     2701 tttgccacct ttgctggtaa actagggaac caaattcatt taaaaaccct aagagatgca
     2761 ttcgtaacag taatgccatt atatattttg gcaggtttaa tcgttctttt gaacaacacg
     2821 gtatttaagt ggattttcca aggggataca ttaacaaaat tccaatattg gggaataaca
     2881 attgcaaacg gtactttaag tatttcaggt atgattattg ctgtaatggt tggttatttc
     2941 ttagctaaaa acagagattt cgaaaacccg ttagcagcat caatgctagc attagtttct
     3001 ttaattgtga tgatgccaaa tacagtttct gtagttcctg acggagcaaa agatgctgta
     3061 aacatttcag gtgttctttc attcaacaac acaggtacag gcgcaatgtt cgccggggtt
     3121 atcgtagcga ttattgcaac agaattattc attgaattat caaacgttaa agctttacaa
     3181 atgaaccttg gtgaaaatat tccaccagct gttagtagat catttagcgt attacttcca
     3241 gtcatgaccg tcatctcctt atttggggtt gtttcagcat tattattcaa tataactgga
     3301 atgaacttaa tctcaatcat tacaatcttt attcaagaac caattcgtca tattggtaca
     3361 agcttaatcg gggtcattat tatttactct ttaggaaata tgttatggct atttggtatt
     3421 caccaagcag ttatttacag tgccatccta gaaccattac tattaattaa cattactgaa
     3481 aacatcactg cagcaaataa tggacaagcc attccacaca tcatcaacct atcacaaata
     3541 caaacattcg ctttaatggg tggtagtgga tctacattat gtttattaat agcaacattc
     3601 ttagtgagtc gcaatgctgt ctctaaaaac gtggctaaat tatcttttgg acctggtatc
     3661 ttcaatatca atgaaccagt attattcggt tacccaatcg tttataacat ttcattagct
     3721 attccattta tcacagttcc agtccttggt attttaatca gctacttagc aacagttaca
     3781 ggattcatga gtcctgcatt tatacaagtt ccttggacta caccagtatt cttaaatgca
     3841 tggttagcaa cagcagggga cgtgagagca gttctagttc aattcatcat ctttgcactt
     3901 ggagttcttc tatacattcc atttatcaaa gttaatgaca aagttgttga acaagaaatg
     3961 gaaggttaag attatgaaac aaattttatt agtatgtaat gcgggaatgt cgacaagtat
     4021 gcttgttaaa aaaatgcaac aaagtgcgac tgaacgtggg attgaaatct ctatccaagc
     4081 aaaatcaatg acagaagcta aaaagaatat ccatgaagca gatgtcattc taattgggcc
     4141 acaaattcgt tatgagttac ttgctgtgaa agaaattgca ggaaatatcc ctgtagatac
     4201 cattgatatg cgggattacg gaatgatgaa tggagcaaaa gttctggaac aagcacttgc
     4261 atggatagga gaaataagat gacagaagaa atggaatata tctgttttca gctcattgcc
     4321 aatagtggag cagccaaatc atcctttatt gaagccatcc aactagctaa ggcaggaaat
     4381 ttaaaagaag cgaaaattaa agttgaagaa gcggaagact ccttagtaga agcgcacaag
     4441 attcactcta atctcataca aaaagaagct actggagaaa aaataggatt ctccttgcta
     4501 tttatgcatg cagaagacca aatggcttca acagagatta ttcagttgct atctaaagaa
     4561 ttcatcgatc tctatcaaaa taaataggaa cactgtcatt cccatctgtc tttattaatg
     4621 acgactacat tgtaggaacc tccaaaagtt ggacaaaatg attgaaagga ttggatcctg
     4681 cattacacaa gatccaatcc ttttctttta ctctagtttt tataatatgt tgaatctaga
     4741 atagtccact gtagtttcta aaaaattgct ggaaatggat gttaagctcc aatttatttg
     4801 tttatatctt atttcagttt actatactag cttattattc tagtgaaaaa ttgaatgagc
     4861 cactatttat ttaatatgta tgatgaggga atgactcaaa aacttcttgt cgatataaga
     4921 atatctgaga tagtatttta aaacgaaagg actataaaag ctcatttcct tcgcacttat
     4981 tttatagaga tctatcatta tactctttag aaatcaaaaa gcaacacacc ttgtcatcgt
     5041 tttatcgtaa atctgttaat gagggggcta gtcttatctg caatctcaaa tcagtgtttt
     5101 gagctgaatg gcactcgttt tctagtttgc tctttgattt taattgggcc ttagtaaata
     5161 ctactcttaa attaaactat agtgaattga aataagatgt gaacaactct atc
//
LOCUS       DBEJKC010000086         5148 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.086, whole genome shotgun sequence.
ACCESSION   DBEJKC010000086 DBEJKC010000000
VERSION     DBEJKC010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5148
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.086"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            281..1826
                     /locus_tag="ACL3G6_001945"
     rRNA            281..1826
                     /locus_tag="ACL3G6_001945"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1878..1950
                     /locus_tag="ACL3G6_001946"
     tRNA            1878..1950
                     /locus_tag="ACL3G6_001946"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1911..1913,aa:Ala,seq:tgc)
     gene            2075..4976
                     /locus_tag="ACL3G6_001947"
     rRNA            2075..4976
                     /locus_tag="ACL3G6_001947"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5053..>5148
                     /gene="rrf"
                     /locus_tag="ACL3G6_001948"
     rRNA            5053..>5148
                     /gene="rrf"
                     /locus_tag="ACL3G6_001948"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1460 a         1042 c         1505 g         1141 t
ORIGIN      
        1 acacgggttc gaatcccgta cggactatgg tatgttgcgg ttggaacact tgatgaaaaa
       61 aagtttaaaa aaagcttaaa aatcttcaaa aaagtgttga caagtgaaag tggctgtgat
      121 atactaatat agttgtcgct tgagagaagc aagtgacaaa gacctttgaa aactgaacaa
      181 gacgaaccaa tgtgcagggc gctacaacat aagttgtagt actgaacaat gaaaaaaaca
      241 ataaatctgt cagtgacaga aatgagtaag aactcaaact tttaatgaga gtttgatcct
      301 ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct gaaggaggag
      361 cttgcttctc tggatgagtt gcgaacgggt gagtaacgcg taggtaacct gcctggtagc
      421 gggggataac tattggaaac gatagctaat accgcataag agtggatgtt gcatgacatt
      481 tgcttaaaag gtgcacttgc atcactacca gatggacctg cgttgtatta gctagttggt
      541 ggggtaacgg ctcaccaagg cgacgataca tagccgacct gagagggtga tcggccacac
      601 tgggactgag acacggccca gactcctacg ggaggcagca gtagggaatc ttcggcaatg
      661 gacggaagtc tgaccgagca acgccgcgtg agtgaagaag gttttcggat cgtaaagctc
      721 tgttgtaaga gaagaacgag tgtgagagtg gaaagttcac actgtgacgg tatcttacca
      781 gaaagggacg gctaactacg tgccagcagc cgcggtaata cgtaggtccc gagcgttgtc
      841 cggatttatt gggcgtaaag cgagcgcagg cggttagata agtctgaagt taaaggctgt
      901 ggcttaacca tagtaggctt tggaaactgt ttaacttgag tgcaagaggg gagagtggaa
      961 ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa caccggtggc gaaagcggct
     1021 ctctggcttg taactgacgc tgaggctcga aagcgtgggg agcaaacagg attagatacc
     1081 ctggtagtcc acgctgtaaa cgatgagtgc taggtgttag accctttccg gggtttagtg
     1141 ccgtagctaa cgcattaagc actccgcctg gggagtacga ccgcaaggtt gaaactcaaa
     1201 ggaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa
     1261 gaaccttacc aggtcttgac atccctctga ccgctctaga gatagagttt tccttcggga
     1321 cagaggtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt
     1381 cccgcaacga gcgcaacccc tattgttagt tgccatcatt cagttgggca ctctagcgag
     1441 actgccggta ataaaccgga ggaaggtggg gatgacgtca aatcatcatg ccccttatga
     1501 cctgggctac acacgtgcta caatggctgg tacaacgagt cgcaagccgg tgacggcaag
     1561 ctaatctctt aaagccagtc tcagttcgga ttgtaggctg caactcgcct acatgaagtc
     1621 ggaatcgcta gtaatcgcgg atcagcacgc cgcggtgaat acgttcccgg gccttgtaca
     1681 caccgcccgt cacaccacga gagtttgtaa cacccgaagt cggtgaggta accgtaagga
     1741 gccagccgcc taaggtggga tagatgattg gggtgaagtc gtaacaaggt agccgtatcg
     1801 gaaggtgcgg ctggatcacc tcctttctaa ggataaggaa ctgcgcattg gtcttgttta
     1861 gtcttgagag gtcttgtggg gccttagctc agctgggaga gcgcctgctt tgcacgcagg
     1921 aggtcagcgg ttcgatcccg ctaggctcca ttggtgagag atcaccaagt aatgcacatt
     1981 gaaaattgaa tatctatatc aaatagtaac aagaaaataa accgaaaacg ctgtagtatt
     2041 aataagagtt tatgactgaa aggtcagaaa ataaggttaa gttaataagg gcgcacggtg
     2101 gatgccttgg cactaggagc cgacgaagga cgtgacaaac gacgatatgc cttgggtagc
     2161 tgtaagtaag cgatgatcca gggatttccg aatgggggaa cccaacaggt aatacctgtt
     2221 acccacatct gttaaggatg tgaggaggaa gacgcagtga actgaaacat ctaagtagct
     2281 gcaggaagag aaagcaaaag cgattgcctt agtagcggcg agcgaaacgg cagaagggca
     2341 aaccgaagag tttactcttc ggggttgtag gactgcaatg tggactcaaa gattatagaa
     2401 gaatgatttg ggaagatcag ccaaagagag taatagcctc gtatttaaaa tagtctttgt
     2461 acctagcagt atcctgagta cggcgggaca cgtgaaatcc cgtcggaatc tgggaggacc
     2521 atctcccaac cctaaatact ccctagtgac cgatagtgaa ccagtaccgt gagggaaagg
     2581 tgaaaagcac cccgggaggg gagtgaaata gaacctgaaa ccgtgtgcct acaacaagtt
     2641 cgagcccgtt aatgggtgag agcgtgcctt ttgtagaatg aaccggcgag ttacgttatg
     2701 atgcgaggtt aagttgaaga gacggagccg tagggaaacc gagtctgaat agggcgcctt
     2761 agtatcatga cgtagacccg aaaccatgtg acctacccat gagcaggttg aaggtgcggt
     2821 aagacgcact ggaggaccga accagggcac gttgaaaagt gcttggatga cttgtgggta
     2881 gcggagaaat tccaaacgaa cttggagata gctggttctc tccgaaatag ctttagggct
     2941 agcgtcgaca ttagagattc ttggaggtag agcactgttt gggtgagggg tccatcccgg
     3001 attaccaatc tcagataaac tccgaatgcc aatgaattat ggtcggcagt cagactgcga
     3061 gtgctaagat ccgtagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
     3121 attgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttag cttagaagca
     3181 gctattcatt caaagagtgc gtaatagctc actagtcgag tgaccctgcg ccgaaaatgt
     3241 accggggcta aaacaattta ccgaagctgt ggataccttt ataggtatgg taggagagcg
     3301 ttctatgtgt gatgaaggta taccgtgagg agtgctggaa cgcatagaag tgagaatgcc
     3361 ggtatgagta gcgaaagaca ggtgagaatc ctgtccaccg taagactaag gtttccaggg
     3421 gaaggctcgt ccgccctggg ttagtcggga cctaaggaga gaccgaaagg tgtatccgat
     3481 ggacaacagg ttgatattcc tgtactagag tatgtagtga tggagggacg cagtaggcta
     3541 actaaagcag acgattggaa gagtctgtct aagcagtgag gtgtgaattg agtcaaatgc
     3601 ttaattctat aacattgagc tgtgatgggg agcgaagttt agtagcgaag ttagtgacgt
     3661 cacactgcca agaaaagctt ctagcgttta aacatactct acccgtaccg caaaccgaca
     3721 caggtagtcg aggcgagtag cctcaggtga gcgagagaac tctcgttaag gaactcggca
     3781 aaatgacccc gtaacttcgg gagaaggggt gctgacttta agtcagccgc agtgaatagg
     3841 cccaagcaac tgtttatcaa aaacacagct ctctgctaaa tcgtaagatg atgtataggg
     3901 ggtgacgcct gcccggtgct ggaaggttaa gaggagtgct tagcgtaagc gaaggtatga
     3961 attgaagccc cagtaaacgg cggccgtaac tataacggtc ctaaggtagc gaaattcctt
     4021 gtcgggtaag ttccgacccg cacgaaaggc gtaatgattt gggcactgtc tcaacgagag
     4081 actcggtgaa attttagtac ctgtgaagat gcaggttacc cgcgacagga cggaaagacc
     4141 ccatggagct ttactgcagt ttgatattga gtgtctgtac cacatgtaca ggataggtag
     4201 gagtctaaga gatcgggacg ccagtttcga aggagacgct gttgggatac tacccttgtg
     4261 ttatggccac tctaacccag ataggtgatc cctatcggag acagtgtctg acgggcagtt
     4321 tgactggggc ggtcgcctcc taaaaggtaa cggaggcgcc caaaggttcc ctcagaatgg
     4381 ttggaaatca ttcgcagagt gtaaaggtat aagggagctt gactgcgaga gctacaactc
     4441 gagcagggac gaaagtcggg cttagtgatc cggtggttcc gtatggaagg gccatcgctc
     4501 aacggataaa agctaccctg gggataacag gcttatctcc cccaagagtt cacatcgacg
     4561 gggaggtttg gcacctcgat gtcggctcgt cgcatcctgg ggctgtagtc ggtcccaagg
     4621 gttgggctgt tcgcccatta aagcggcacg cgagctgggt tcagaacgtc gtgagacagt
     4681 tcggtcccta tccgtcgcgg gcgtaggaaa tttgagagga tctgctccta gtacgagagg
     4741 accagagtgg acttaccgct ggtgtaccag ttgtcttgcc aaaggcatcg ctgggtagct
     4801 atgtagggaa gggataaacg ctgaaagcat ctaagtgtga aacccacctc aagatgagat
     4861 ttcccatgat tatatatcag taagagccct gagagatgat caggtagata ggttagaagt
     4921 ggaagtgtgg cgacacatgt agcggactaa tactaatagc tcgaggactt atccaaagta
     4981 actgagaata tgaaagcgaa cggttttctt aaattgaata gatattcaat tttgagtagg
     5041 tattactcag agttaagtga cgatagccta ggagatacac ctgtacccat gccgaacaca
     5101 gaagttaagc cctagaacgc cggaagtagt tgggggttgc cccctgtg
//
LOCUS       DBEJKC010000087         4639 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.087, whole genome shotgun sequence.
ACCESSION   DBEJKC010000087 DBEJKC010000000
VERSION     DBEJKC010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4639
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.087"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..>4639
                     /gene="zmpD"
                     /locus_tag="ACL3G6_001949"
     CDS             <1..>4639
                     /gene="zmpD"
                     /locus_tag="ACL3G6_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease ZmpD"
                     /protein_id="HGR0546415.1"
                     /translation="EVQPALPEAVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAY
                     TEPVGTTGVDENGNLIEPPVNDIPEYTEPISTVSEVASEREELPSLHTDIRTETIPKT
                     TIEESDPSKFIGDNSVKQVGEDGERQIVTSYEELHGKKISESVETVTILKEMKPEIIV
                     KGTKERPKEKTAPVLTLTKVTEDAMNRSANLNYELDNKDNAEISSIVAEIKDGDTVVK
                     RVDLSKEKLTDAVQNLDLFKDYKIATTMIYDRGQGSETSKLDERPLRLELKKVEIKNI
                     ASTNLVKVNDDGTETPSDFMNEKPSEEDVKKMYLKITSRDNKVTRLTVDSIEEVTEEG
                     QKLYKITAEAQDLIQHTDPTKVRNKYVYYIEKPHPKEDNVYYNFKDLVDAMNTDKNGT
                     FKLGADLNATGVPTPKKWYVDGDFRGTLKSVEGKHYTIHNTERPLFQNIIGGTVTKVN
                     LGNVNINMPWADRIAPIADTIKGGAKIEDVKVTGNVLGRNWVSGFIDKIDNQGTLRNV
                     AFIGNVTSVGDGGQFLTGIVGENWKGLVERAYVDANLIGKKAKAAGIAYWTQNSGDNH
                     KVGVEGAVKKGIVKGTIQVESPVEVGGAVGRLSHHGYIGEVVSMMKVKKGEIFYGSSD
                     MNDDPYWVANNVRGNYVVNGVSEGTISYARAKEHHRIKPISQSEADTKIMMLGITAQD
                     FAINEPVVNRLNRLTRKEDEYKSTQDYKVDRDLAYRNIEKLQPFYNKEWIVNQGNKLA
                     EDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGTKEEMDVTKNADSKVKQVRE
                     YTIAGQNVVYTPNMVEKDRNQLIQDIKDKLASVQLISPEVRALMDARKKPEENTDERK
                     NGYIKDLYLEESFAETKANLDKLVKSLVENADHQLNSDEAAMKALVKKVDENKAKIMM
                     ALTYLNRYYDIKYGDMTIKNLMMFKPDFYGKSVDLLDFLIRIGSSERNIKGDRTLDAY
                     RDMIGGTIGKSELHGFLDYNMRLFTNDTDLNDWFIHAAKNVYVSEPQTTNPDFVNKRH
                     RAFDGLNNGVHNRMILPLLTLKNAHMFLISTYNTMAYSSFEKYGKYTEEARNEFKKEI
                     DKVAHAQQTYLDFWSRLALPSVRDQLLKSENRVPTPVWDNQNYSGIKGINRMGYDEKK
                     VPIAPIRELYGPTWKFHNTNWNMGAMASIFPNPNNNDQVYFMGTNMISPFGISAFTHE
                     TTHVNDRMLYFGGHRHRQGTDVEAYAQGMLQTPSSIGHQGEYGALGLNMAYHRENDGD
                     QWYNYDPDKLQTREDIDRYMKNYNEALMMLDHVEADAVLPQLNGDNSKWFKKIDREMR
                     RNLGDGLNNLVAPHQWDNVRDLNQEESSKKLSSINDLIDNNFMTKHGNPGNGRYRPED
                     FRPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYDKGFTSYVSSKYQG
                     EADKQNQGRLGDDFIIKKVSNNQFSNLEDWKKYWYHDVKSRAEKGFTEITIDGQTIHN
                     YNELKDLFDKAVTEDLKKAGNYSNTENLKSKVFKALLKNTDGFFNPLFKKDI"
BASE COUNT         1657 a          725 c          966 g         1291 t
ORIGIN      
        1 gaagtacaac cagccttacc cgaagcagtt gtaactgaaa aaggcgaacc agaagttcat
       61 gagaagcctg actatacgca accaataggt gcaaaccttg ttgagcctga agttcatgag
      121 aaactagcat acactgaacc tgtaggtaca acaggagtag atgaaaatgg aaacttgatt
      181 gagccacctg ttaacgatat tccagagtat actgaaccaa tatctacagt ttcagaagtt
      241 gcatcagaaa gagaagagtt gccttcttta cataccgata ttcgtacaga gactattcct
      301 aaaaccacta tagaagaatc tgatcctagc aaatttatag gcgataattc tgttaaacaa
      361 gttggtgagg atggcgaacg tcaaattgtt actagctatg aagagttaca tggcaaaaaa
      421 atcagcgagt cagttgaaac agtaacaatt ttgaaagaaa tgaagcctga aattattgta
      481 aaaggtacaa aagaaagacc aaaagaaaaa acggctcctg ttttaacctt gaccaaagta
      541 acagaagatg ctatgaatcg ttctgccaac ttaaattatg agcttgataa taaagataat
      601 gctgaaatat caagtattgt agctgaaatt aaagatggtg atacagtagt taaaagggtt
      661 gatttatcta aagaaaaatt aactgacgct gtacaaaatt tggatttgtt taaagattat
      721 aagattgcaa caacaatgat ttatgatcgt ggtcaaggtt ctgaaacgtc taaactggat
      781 gaaagacctc tgcgtttgga gttgaaaaag gtcgaaatta aaaatatcgc atctactaat
      841 ttagtgaagg taaatgatga tggtactgaa acacctagtg attttatgaa tgaaaaacct
      901 tcagaagaag atgttaaaaa aatgtactta aaaatcacta gtcgcgataa taaggtaact
      961 cgtttaactg tagactctat tgaagaagtg actgaagaag gtcaaaaact ttacaaaata
     1021 actgctgaag cacaagattt gattcaacac acagacccaa cgaaggttcg taataagtat
     1081 gtttattata tagaaaaacc ccatcctaaa gaagataatg tctactataa ctttaaagat
     1141 ttagtagatg ctatgaatac tgataaaaat ggtacattta aacttggtgc agatttgaat
     1201 gccactggtg ttccaacacc taagaaatgg tatgttgacg gcgactttag aggtacattg
     1261 aagagtgtag aggggaaaca ttatactatc cacaacacgg agcgtccgtt attccagaat
     1321 attattggtg gtacagtaac caaagtaaat ctgggaaatg taaatatcaa tatgccatgg
     1381 gcagaccgca tcgcaccgat tgctgacact attaaaggtg gcgctaaaat tgaagatgtc
     1441 aaagtgactg gtaacgtatt aggtagaaac tgggtatctg gatttattga taagattgac
     1501 aaccaaggta cactcagaaa tgtagccttt atcggaaatg tgacatctgt aggtgatggt
     1561 ggtcaattct tgaccggtat cgttggtgag aactggaaag gactagtcga acgtgcgtat
     1621 gttgacgcaa atcttattgg caagaaagcc aaggctgctg gtattgctta ttggacacaa
     1681 aacagtggtg acaatcataa agttggtgtc gaaggtgcag tcaagaaagg aattgtgaag
     1741 ggtaccattc aggtagaaag tcctgttgaa gtcggcggtg ctgttggacg tttgagtcat
     1801 catggttata tcggggaagt cgtatctatg atgaaagtta agaagggtga aattttttat
     1861 ggttctagtg atatgaatga tgacccatat tgggtggcga ataatgtacg aggaaattat
     1921 gtagttaatg gtgtgagtga aggtacgata tcttatgctc gtgctaaaga acaccatcgt
     1981 atcaaaccaa tttcacagtc agaagcagat actaaaatta tgatgttagg tattacagca
     2041 caagattttg ctatcaacga acctgtggtc aatcgcttaa accgtttaac cagaaaagaa
     2101 gatgaatata agtcaaccca agactataaa gtagatcgag atctggctta tcgtaatatt
     2161 gagaaacttc aaccatttta taacaaagaa tggattgtca accaaggtaa caaacttgca
     2221 gaagattcaa acttagctaa gaaagaagtc ctttctgtta cgggtatgaa ggatggacag
     2281 tttgtaactg acttatcaga tattgataag attatggttc actatgctga tggtactaaa
     2341 gaagaaatgg acgtcactaa gaatgctgat tctaaagtga aacaagttcg tgaatatacc
     2401 atcgctggac aaaacgttgt ttatacacca aatatggttg agaaagaccg taaccaattg
     2461 attcaagata tcaaagataa gttggcgtca gttcaattga tttctcctga agtacgtgct
     2521 ttgatggatg cacgtaagaa accagaagaa aatactgatg aacgtaagaa tggttatatt
     2581 aaagaccttt acttagaaga aagctttgct gaaacgaaag ctaatcttga taaattggtt
     2641 aaatccttag ttgaaaatgc agatcatcaa ttaaatagtg acgaagcggc tatgaaagca
     2701 cttgttaaga aggtggatga aaataaagct aaaatcatga tggctctgac ttatctcaat
     2761 cgttactatg atatcaagta tggggatatg actatcaaga acttgatgat gtttaaacct
     2821 gatttctatg gtaaatcagt tgaccttctt gatttcttga ttcgaattgg atcaagtgag
     2881 agaaatatca aaggtgacag aactttggat gcttatcgtg atatgattgg tggaactatt
     2941 ggtaagtctg aattacatgg attcttagat tacaatatgc gtctcttcac taacgatact
     3001 gatttaaatg attggttcat ccatgcagct aagaatgtat atgtatcaga acctcaaaca
     3061 acgaacccag attttgttaa taaacgacat cgtgcatttg atggtttgaa caacggtgtt
     3121 cataatcgta tgattctacc tctattaact cttaagaatg cacatatgtt cttgatttca
     3181 acttacaata caatggctta tagttctttt gagaaatatg gtaagtatac agaagaagct
     3241 agaaatgaat tcaaaaaaga aattgataag gttgcacatg ctcaacaaac atacttagac
     3301 ttctggtcac gtttagcatt gccaagcgta cgtgaccaat tactcaagag tgagaatagg
     3361 gtaccaactc ctgtgtggga taaccaaaac tatagtggta ttaaaggaat aaaccgtatg
     3421 ggttatgatg agaagaaagt accaattgcg ccaattcgtg agttatatgg tccaacttgg
     3481 aaattccata ataccaactg gaatatggga gctatggcat ctattttccc aaatcctaat
     3541 aacaatgacc aagtttattt catgggaaca aatatgatta gtccgtttgg tatttcagcc
     3601 tttactcatg aaactacaca cgttaatgat agaatgcttt acttcggtgg tcatagacac
     3661 cgtcaaggta cagacgtcga agcctatgct caaggtatgc tacaaactcc gtcaagtatt
     3721 ggtcaccaag gtgaatatgg tgctttaggt ttgaacatgg cttatcatcg tgaaaatgat
     3781 ggtgaccaat ggtataacta tgaccctgat aagcttcaaa ctcgtgaaga tatcgatcga
     3841 tatatgaaaa actataatga agcactgatg atgctagatc atgtagaagc agacgccgta
     3901 cttccacaat tgaatggtga taatagcaag tggttcaaga aaattgatag agaaatgcgc
     3961 agaaatcttg gggatggttt gaataactta gtagcaccgc accaatggga caacgttcgt
     4021 gacttaaatc aagaagagag ttctaagaaa ttatcaagta ttaacgattt gattgataat
     4081 aatttcatga ccaaacacgg aaatccaggt aacggacgtt atagaccaga ggattttaga
     4141 ccaaactcag cttacgtaaa tgtcaatatg atggcaggaa tttacggtgg gaatacgagt
     4201 caaggtgctc ctggttcatt atcgttcaaa cataatgcct tccgtatgtg gggttattat
     4261 ggatatgaca aaggtttcac tagttatgta tctagcaaat atcaaggtga agctgataaa
     4321 caaaaccagg gtagattagg tgatgatttc attatcaaaa aagtttcaaa caaccaattc
     4381 tcaaatcttg aagattggaa gaaatattgg tatcatgatg tgaaatccag agctgaaaaa
     4441 ggattcacag agattacaat tgatggacaa accattcaca actataatga actgaaagac
     4501 ttattcgaca aagctgtcac agaagacctc aagaaagctg gaaactactc aaatactgag
     4561 aatttgaaat ccaaagtctt caaagctctt cttaaaaaca cagacggttt ctttaatcca
     4621 ttgttcaaaa aagacattt
//
LOCUS       DBEJKC010000088         4509 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.088, whole genome shotgun sequence.
ACCESSION   DBEJKC010000088 DBEJKC010000000
VERSION     DBEJKC010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4509
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.088"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            23..520
                     /locus_tag="ACL3G6_001950"
                     /pseudo
     CDS             23..520
                     /locus_tag="ACL3G6_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234238.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
     gene            677..1102
                     /gene="lacA"
                     /locus_tag="ACL3G6_001951"
     CDS             677..1102
                     /gene="lacA"
                     /locus_tag="ACL3G6_001951"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HGR0546416.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1133..1648
                     /gene="lacB"
                     /locus_tag="ACL3G6_001952"
     CDS             1133..1648
                     /gene="lacB"
                     /locus_tag="ACL3G6_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HGR0546417.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1659..2588
                     /locus_tag="ACL3G6_001953"
     CDS             1659..2588
                     /locus_tag="ACL3G6_001953"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HGR0546418.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2590..3570
                     /gene="lacD"
                     /locus_tag="ACL3G6_001954"
     CDS             2590..3570
                     /gene="lacD"
                     /locus_tag="ACL3G6_001954"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HGR0546419.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQRTATSWKERV"
     gene            3976..4452
                     /locus_tag="ACL3G6_001955"
     CDS             3976..4452
                     /locus_tag="ACL3G6_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546420.1"
                     /translation="MNVDGNKFYNVSVSEDIVNAGQILEDYFYVDKFGNINLKGTPEE
                     LAKNIGISVQEASLMYEAVKELPNVYERGPVGFRFNLGPQVRGMGGWAAGAFATGYAG
                     WHLKQFAVNPVTSGFVAVISGAIGWAVKTAVENYWTVAVATVEVPFVNLVYTIDLP"
BASE COUNT         1463 a          747 c          966 g         1333 t
ORIGIN      
        1 attctagttt ttcaggaagt ctaataaaga aactagcaag gtcaggcctt actttattgg
       61 tggacatcca ggatttaatt gtcctctact tgatgatgaa gtctatgaag attattatct
      121 agagtttgag aaagaagaga cttgctctgt tccacgtcct ttcccagaaa caggtatgtt
      181 ggatttccaa gatagaagtc catggctaga gggacaaaaa gaaatagatc ttagttatga
      241 tcttttcagc acagatgcag tgactttgga tgaattgcaa tctcgaacaa ttgcccttcg
      301 ttctcttaaa catgataagg gattgaaagt gcattttgca gaatttccaa acctcatcat
      361 ctggtcaact ttgaacaagg gacctttcat tacctttgaa ccatggtctg gcttgtcaac
      421 atcccttgaa gaaggagatc atttagaaga taagaagaat gtttgtctct tagaagccaa
      481 tcaggttgaa gaattagggt ttgagataga agttttataa aaaagtaaaa aataaataac
      541 aaaaacaaac acaaactatt gacttcttca aacaatagta gtatattatg tttgtgagga
      601 ctaattgact gttttttaaa gatagccaat acactgctgg aatccagcat agaaaaaata
      661 aaaaggagta tacaatatgt ctattgttat cggtgcagat gctgcaggtt tgagattgaa
      721 agaagttgtg aaagacttct tagaaaaaga aaacttccac cttgtggatg ttacagctga
      781 aggtcaagac tttgttgatg tgactctcgc tgttgctgca gaagtaaaca aagaagaaca
      841 aaaccttggt atcgtgattg atgcttatgg agctggtcca tttatggttg caactaagat
      901 caaaggaatg gttgctgcag aagtatctga cgaacgttca gcttatatga ctcgtggcca
      961 caacaactca cgtatgatca ctatgggggc acaacttgtt ggtgatgaat tggctaaaaa
     1021 catcgctaaa ggatttgtta atggtaaata cgacggtggt cgtcaccaaa tccgggttga
     1081 catgttgaac aaaatgggct aattagatta tagtaagaaa ggtaagttaa aaatgagaat
     1141 tgcaattgga tgtgaccaca tcgtaactga tgaaaaaatg gcggtttcag aatttttgaa
     1201 atcaaaagga tatgaagtca ttgactttgg tacatatgac catacacgga ctcactaccc
     1261 aatctttggt aaaaaagtag gggaagcagt aactagtggt caagctgatc ttggggtatg
     1321 tatctgtggt actggtgttg gtatcaacaa cgctgtaaat aaagttccag gtgttcgttc
     1381 tgccttggtt cgtgatatga caacagccct ttatgctaaa gaacaattga acgctaacgt
     1441 tatcggcttt ggtggtaaga ttactggtga attgcttatg tgtgatatca tcgaagcttt
     1501 cattcatgct gaatacaaac catctgaaga aaacaagaaa ttgattgcga aaattgaaca
     1561 ccttgaaagt cacaatgctc aacaaacaga cgcaaacttc tttacagaat tccttgaaaa
     1621 atgggatcgc ggagaatacc acgactaaga ggtgacctat gattttaaca gtcacaatga
     1681 acccatccat tgatatttcc tatcccttgg atgagttgaa gattgatact gtcaatcgtg
     1741 tggtggatgt aaccaaaacg gctggtggta agggacttaa tgttacccga gtactttcag
     1801 aatttggcga ttctgttctt gctactggtt tagtgggtgg caaacttggt gagtttttgg
     1861 ttgaacatat cgataatcaa gtaaagaaag atttcttctc aattcaggga gaaactcgta
     1921 actgtatcgc tattctccac ggagacaacc aaacagaagt tcttgaaaaa ggtcctgaag
     1981 tattggaaca ggaaggtcaa gactttttgg aacatttcaa aaaactcttg gagtcagttg
     2041 aagtagtggc catctcaggt agtctgccag ctggccttcc agttgattac tatgcgagct
     2101 tggtagaact tgctaatcaa gctggcaagc ctgtagtctt ggactgctca ggtgcagcac
     2161 ttcaggctgt tcttgaatca ccccataaac caacagtcat caaaccaaat aatgaagaat
     2221 tgtctcagct tcttggaaga gaagtttctg aggatttgga tgaattaaaa gaagtacttc
     2281 aagaaccttt gtttgcaggg attgaatgga ttatcgtttc acttggtgcc aacggtactt
     2341 ttgccaaaca tggtgacact ttctacaagg tagatattcc tagaattcag gtggtaaatc
     2401 ctgttggatc tggagactct actgtggcag gaatttcttc aggacttctt cacaaagaat
     2461 cggatgcaga attactcatc aaggcaaatg tccttggtat gctcaatgct caagaaaaaa
     2521 tgactggtca tgtcaacatg gccaactatc aagctctata tgatcaatta atagtaaaag
     2581 aggtataaaa tggctttaac agaacaaaaa cgtgtacgct tagaaaaact ttctgatgaa
     2641 aatggtatca tctcagctct tgcatttgac caacgtggtg ctttgaaacg cctcatggct
     2701 caacaccaaa cagaagaacc aactgtggcc caaatggaag aacttaaagt cttggtagca
     2761 gatgaattga ctaaatacgc ttcatctatg cttcttgacc ctgagtatgg acttccagca
     2821 actaaagctc ttgatgaaaa agctggtctt ctccttgctt atgaaaaaac aggttatgac
     2881 acaacaagca caaaacgctt gccagactgc ttggatgttt ggtctgcaaa acgtattaaa
     2941 gaagaaggtg cagatgcagt taaattcttg ctttactatg atgtagatag ctcagacgaa
     3001 ctcaatcaag aaaaacaagc ctacatcgaa cgcatcggtt ctgagtgtgt ggctgaagat
     3061 atcccattct tccttgaaat ccttgcttac gatgaaaaaa ttgcggatgc aggttctgta
     3121 gaatacgcta aagtaaaacc acacaaagtt atcggcgcta tgaaagtctt ttcagaccca
     3181 cgctttaaca ttgatgtttt gaaagttgaa gttcctgtta acattaaata tgttgaaggc
     3241 ttcgctgaag gtgaagtagt ttatacacgt gaagaagcag cagccttctt caaagcgcaa
     3301 gatgaagcaa cgaacttgcc atacatctac ttgagtgctg gtgtatcagc taaactcttc
     3361 caagatactc ttgtatttgc tcatgaatca ggtgcaaact ttaacggagt tctttgtggc
     3421 cgtgctacat gggcaggatc agttgaagct tacatcaaag atggtgaagc agcagctcgc
     3481 gaatggcttc gcacaactgg atttgaaaac attgacgaac tcaacaaagt tcttcaaaga
     3541 acagcaactt catggaaaga acgcgtgtaa gaaagtcctc ctagtttagg aacatgaatc
     3601 taaaaaaatt taaaaaaagt tgtatgtaaa ggtttacaaa ataacttact tgtgctatac
     3661 ttaaatcaca agttaatatg aattagaaag taactatatg aagtataata aaaataggat
     3721 atagtttatt ttacgagcta ggaaggaaaa atacggaaac aatattgcca gaataaacta
     3781 tatttagatg cacatttcat tcattgtttt ataaaaggag aagataaacg gctactaaaa
     3841 agagttttaa agcgttagtt gtaggactag gtattgtttc aatattctca tcagccttac
     3901 ctatggttag tggttctgta tttgcagata gtgccctaac tacagtatac agtagataaa
     3961 gcaaatgata ttgttttgaa tgttgatggg aataaatttt ataatgtttc ggtttcagaa
     4021 gatattgtaa atgctggtca aattttggaa gattattttt atgtagataa atttggaaat
     4081 ataaatttaa aaggcactcc tgaagagtta gcaaaaaata ttggtatttc tgtacaagaa
     4141 gcaagtttga tgtatgaagc tgtaaaagag ttacccaacg tttacgaaag aggtcctgta
     4201 ggttttcgtt tcaatcttgg tcctcaagtg agggggatgg gtggctgggc tgctggagct
     4261 ttcgctactg gatatgctgg atggcatttg aaacaatttg cggttaatcc tgttacatct
     4321 ggatttgttg ctgtaataag tggtgcgatt ggctgggctg taaaaactgc tgtagaaaat
     4381 tattggacag ttgctgtagc tacagtagaa gtgccgtttg tgaaccttgt ttacaccata
     4441 gatttacctt agaggttatt tctttatgaa tcattctttt aaaaaaataa ctgtattttg
     4501 ttttatagt
//
LOCUS       DBEJKC010000089         4463 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.089, whole genome shotgun sequence.
ACCESSION   DBEJKC010000089 DBEJKC010000000
VERSION     DBEJKC010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4463
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.089"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..736)
                     /locus_tag="ACL3G6_001956"
     CDS             complement(<1..736)
                     /locus_tag="ACL3G6_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0546421.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYL"
     gene            complement(736..2301)
                     /locus_tag="ACL3G6_001957"
     CDS             complement(736..2301)
                     /locus_tag="ACL3G6_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGR0546422.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            2439..4328
                     /locus_tag="ACL3G6_001958"
     CDS             2439..4328
                     /locus_tag="ACL3G6_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HGR0546423.1"
                     /translation="MKKTFFLLMFGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSRFERDCLNLAFSGKKEATLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKTLQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
BASE COUNT         1235 a          822 c         1026 g         1380 t
ORIGIN      
        1 tgagataacg ttgaagaaat tcttttgtac ggtcttcttt aggattagtg aagaggtctt
       61 ctggtttacc ttcttcagca atcacaccct tatccataaa gataacacgg tgagagacat
      121 cacgggcaaa ttccatttca tgggttacga caatcatggt caagccttcc tgagccagat
      181 cttgcatgat tttgaggacc tctccaacca tttctggatc gagagctgat gttggttcat
      241 caaagagaat ggcgtcagga ttcattgaaa gggcacgagc gatggccaca cgttgttttt
      301 gaccacctga gagttgtttg ggtctcgctt gccagtagcg ttctcccatg ccgacctttt
      361 ccaggttttc tttggcaatt tcttcagctt ctgtgcgttc gcgtttaagg acagttgtct
      421 gagcgacgat tgtgttttca agaacgttga gattttcaaa gaggttaaag gattggaaaa
      481 ccatccctaa cttttcacgg tattgcgtga ggtcatagcc tttttcgagg acgttttgtc
      541 catgataaag gatttgtcca tcagttggcg tttcaagtag gttaatggag cgtaggaagg
      601 ttgatttccc acttccagag cttccgatga tagaaataac ttctcccttg tggacagtga
      661 gagaaatgtc ttttagcact tcgttttgtc cataggattt tttgaggtgt ttaatttcaa
      721 ggattgcttg tgtcattatt tcaaatcctc cgtttgcatt tggttagcac ctgtagtgta
      781 ggtatccatg tccattctgc gctcgataaa gcgtaggata cgtgttacgg tgaaggtgag
      841 gacaaagtaa atcacggcga tgattgtaaa tgtctggaag tattgatagg tttgtgttgc
      901 cacggtattt cctgagaaat aaagttcgac aacagagata acgttcaata cagatgtatc
      961 tttgatattg atgacaaatt cattaccagt tgcaggtagg atgttacgga ctacctgagg
     1021 taggacaatc ttacgcatgg tctggttatg ggtcatacca agagcagtcg cagcttcaaa
     1081 ttgtcccttg tcaactgcta ggataccacc acggacgatt tcagtcatgt aggcaccggt
     1141 attgattgaa acgatgaaga tagcagccag tgtacggtca aggttgatcc cgaaagcttg
     1201 ggcagttcca tagtagataa ccatcgattg aacaatcatt ggcgtaccac ggaaaatttc
     1261 aatgtagaca ttgagaaccc agccgactag tttttgaagg ccataaatgg ctttgttttc
     1321 agagagagga gcagtacgga agacaccaat ggcaagtcca ataatgagac ctatgatggt
     1381 tccgacgata gagattaaaa gagtgatacc agcaccacgc aagagttgtt gccagttttc
     1441 agaaagaatt ttagcgactt ggctaaagaa actactgcta gtctcttcag ttgttgtagc
     1501 ttcggcaggt tgttccttga tcatacgatc catcagggca acttggtcgt cctttgaaat
     1561 ggtttcaatg ctggcattga tttggctaat acgattgtca tttttacgaa gcccgatagc
     1621 gatagctgta tcttcttccc cagttttgaa accaggttct acttgaatca tcttgaactt
     1681 agagttcgca gcttcagcag tcagtgcttc tggacgttca gaaacataag catcaatgac
     1741 accagcctca agagcttgtc gcatttgagc gaagtctccc atggctgttt cttttttagc
     1801 acctgggatt tgtgcaatca agtcgtagag gtagacccct tgttgagaag tgatttttgc
     1861 accgttaaag tcatccaaag atttagcact tgcgtaggca gaatcttttt tgacaagcaa
     1921 aactggttcg ctagtgtagt aactgctcga aaaggcaatt tcttgtttgc gttctgcagt
     1981 tggactcata cctgcgataa tcatgtcaat cttaccagaa gtaagggcag ggactagacc
     2041 ttcccacttg gttttaacaa ccaaaggttc tttacctaag tccttagcga ttttcttggc
     2101 gatttgaaca tcgtatccgt tggcatactg attggtccca tcgattttga cagctccgtt
     2161 gctatcatca tcctgggtcc agttaaaggg agcatatgct gcttccatcc cgatgcgtaa
     2221 atattcatcg gcttgagcaa cattgacaag tcctagcatc agcaagagac ttgtgaaaat
     2281 agataagtat atttttctca tgatttctcc tattctgatc tattaaaaaa taactgtctc
     2341 ctattttatc gaaaaatgcg taatttttca acataagtaa gcctttactt acgaaaaaat
     2401 gctataatga taagaaagat aaaaaggggg cttaattgat gaaaaaaact tttttcttac
     2461 tgatgtttgg cttgttttgc cttctgccac tttctgtttt cgccattgat tttaagataa
     2521 actcttatca aggtgatttg tatattcatg cagacaatac ggcagaattt agacaaaaga
     2581 tagtttatca gtttgaggag gactttaagg gacaaatcgt gggacttgga cgtgctggta
     2641 agatgcctag cgggtttgac attgaccctc atccaaaggt tcaggccgcg aaaaacggtg
     2701 cagaactagc agatgtgact agcgaagtaa cagaagaagc ggatggttat actgtgagag
     2761 tctataatcc aggtcaggag ggcgacatag ttgaagttga cctcgtctgg aacttaaaaa
     2821 atttactttt cctttatgat gatatcgctg aattaaattg gcaacctctg acagatagtt
     2881 cagagtctat tgaaaagttt gaatttcatg taaggggaga caagggggct gaaaaactct
     2941 ttttccatac agggaaactt tttagagagg gaacgattga aaagagtaac cttgactata
     3001 ctatccgttt agacaatctt ccggctaagc gtggagttga gttgcatgcc tattggcctc
     3061 ggaccgattt tgctagcgct agggatcagg gattgaaagg gaatcgttta gaagagttta
     3121 ataagataga agactcgatt gttagagaaa aagatcagag taaacaactc gttacttggg
     3181 tcctcccttc gatactttct atctccttgt tattgagtgt ctgcttctat tttatttata
     3241 gaagaaagac cactccttca gtcaaatatg ctaaaaatca tcgtctctat gaacccccaa
     3301 tggaattaga gcctatggtt ttatcagaag cagtctactc gacctccttg gaggaagtga
     3361 gtcccttggt caagggagct ggaaaattca cctttgatca acttattcaa gctaccttgc
     3421 tagatgtgat agaccgtggg aatgtctcta ttatttcaga aggagatgca gttggcttga
     3481 gattggtgaa agaagatggt ttgtcaagat ttgagagaga ctgtctaaat ctagcctttt
     3541 caggcaaaaa agaagccact ctttccaatt tgtttgcgga ttacaaggta tctgatagtc
     3601 tttatcgtag agccaaagtt tctgatgaaa aacggattca agcaagaggg cttcaactca
     3661 aatcttcttt tgaagaggta ttgaaccaga tgcaagaagg agtgagaaaa cgagtttcct
     3721 tctgggggct cccagattac tatcgtcctt taactggttt ggaaaagact ttgcaagtgg
     3781 gtatgggtgt cttgactatc ttgcccctat ttatcggatt tggtttgttc ttgtacagtt
     3841 tagacgttca tggctatctt tacctccctt tgccaatact tggttttcta gggttagttt
     3901 tgtctgtttt ctattattgg aagcttcgac tagataatcg tgatggtgtt ctaaatgaag
     3961 cgggagctga ggtctactat ctctggacca gttttgaaaa tatgttacgt gagattgcac
     4021 gactggataa ggctgaattg gaaagtattg ttgtttggaa tcgtctcttg gtctatgcaa
     4081 ccttatttgg ctatgcggac aaggttagtc atttgatgaa ggttcatcag attcaagttg
     4141 aaaatccaga tatcaatctc tatgtagctt atggctggca cagtatgttt tatcattcaa
     4201 gcgcgcaaat gagccattat gctagtgtcg caaatacagc aagtacctac tccgtatctt
     4261 ctggaagtgg aagttctggc ggtggcttct ctggaggcgg aggaggcggc agtatcggag
     4321 ccttttaaag agagctacca tagactgaaa aagtatgata taatggaaga tagaagaaag
     4381 acaaactata agaaaagtca atagttttat ctaaactatt tcttatttca atttgatgat
     4441 ttggcgatga ttttagagca cgg
//
LOCUS       DBEJKC010000090         4378 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.090, whole genome shotgun sequence.
ACCESSION   DBEJKC010000090 DBEJKC010000000
VERSION     DBEJKC010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4378
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.090"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            256..1659
                     /locus_tag="ACL3G6_001959"
     CDS             256..1659
                     /locus_tag="ACL3G6_001959"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HGR0546424.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGP
                     YILSDKRWDEAPIYLRYGVFRPSRDDEKKVVIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSERLASECKALKILNEWSEMPKIYWYGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAAPGFRAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKAFLLVN"
     gene            1848..2432
                     /locus_tag="ACL3G6_001960"
     CDS             1848..2432
                     /locus_tag="ACL3G6_001960"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0546425.1"
                     /translation="MKDVVYSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLIN
                     GSLKPQKGYVNLLSHGKKSSDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVL
                     KKVNLYEELEKIDILNYQCGENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDN
                     DNSNSIHDILFNLGISFIEVSHHYDLNDKRYTDI"
     gene            2481..3221
                     /locus_tag="ACL3G6_001961"
     CDS             2481..3221
                     /locus_tag="ACL3G6_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0546426.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            3224..>4378
                     /locus_tag="ACL3G6_001962"
     CDS             3224..>4378
                     /locus_tag="ACL3G6_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546427.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIK"
BASE COUNT         1526 a          555 c          822 g         1475 t
ORIGIN      
        1 agttatggat ctcgttccaa tatgtgcacg ttggaatgtc agtgcttata tggggggaat
       61 ccaaaggatt ctcccttttt attttaataa gtctgtctag ctatagatat attaagtttg
      121 atagaatttc ttggagattt tgttatggat tataatttca atttggagca tcctttcttt
      181 ttcactaata atgattatag tacagatact agcataaagt actaagtaag tctgcctttt
      241 aattggcacg aagtaatgaa taatgatgag tgggtttatc aataccctat tggaaaattt
      301 gttgaaagac aagggtggaa aatacacatt agttcagagt ataatagttc acacgaattg
      361 ttacaagatg tagcaaaaat ttgccatgaa atgcgaattc catttaaaca tcttagtaca
      421 gaagacaaat ttatcatgcg aaacgggaaa ttggttagtc gaggattttc tggtaaattt
      481 attacatgtt atccaaatca aaatgaatta gagtcggttt tgcaaaggtt agaaagtgcc
      541 ttaaagcaat ataatgggcc atatatttta agcgataaac gttgggatga agcaccaata
      601 tatctgaggt atggtgtgtt taggccgtca agggatgatg aaaagaaggt tgttattgat
      661 gaattaattg ttggcgatga agttgttaaa gatgaacgtt taccagtatt taaaattcca
      721 aaaggtatag tgccccctga ctttttgaat aaatggcttg acaagaaaga taaaaaacag
      781 ggagactttc cctttattat agataatgca attagatttt caaacagtgg tgggatatat
      841 aatgctagac taaaagaaga tgggaaaaaa ataattttaa aagaggctag accgtataca
      901 ggtctaggat ttgatggtac ttattcttca gagagattag cttcggagtg caaagcacta
      961 aaaattctaa atgaatggag tgagatgcct aaaatatact ggtacggtaa gatctgggag
     1021 cacaccttct taggaattga acatatgaag ggcgttccac taaatagatg ggttaccaat
     1081 aattttcctt tatatgaagt tgttgataag accaaagatt atctattgag agtttcaaag
     1141 atagtagaaa aactcatcga tttaacgaat aagtttcatt ctgaaaatgt atatcatcaa
     1201 gatttacatt taggaaatat cttggttaag gatgaagatg agattagtat aatagactgg
     1261 gaacaggctg tcttttcgaa tgatgaaaaa gttgtacata aagttgcagc ccctggtttt
     1321 agagcatggc gagaaacact tcccagtgag atagattggt atggtattag acaaatagct
     1381 cattatttat acatgccact agtaactaca tcggatttga catacaacta tgtaagtcaa
     1441 accaggatag aaggaaaaaa actatttgag tctttgggtt atacaagaga acatatagat
     1501 tatgtagaaa gtttattgtc atatctagat tctaaatgtc cacagattga gaatatttcc
     1561 aggaaaaaag ttttaaaacc catgcatgag attagaacta tcgagagtga gcaagatata
     1621 caagatttta ttataaaagc ttttctttta gtgaactgat aggtattttc ttagcaaacg
     1681 ataaagtttt agggccgata caatcaattg cctattcatt aaataagata aatacaacca
     1741 aagatttaag gaaaccgttt ttaaaatact taagtggaga gaagaatttt atagacgctg
     1801 aacatgataa taacggactg tatacttcat caatagatgt gatacacatg aaagatgttg
     1861 tatattctat tacaccagaa aataaattaa gtattgactt ctcatttaag tcaccattta
     1921 gggtattatt aacaggaact tctggtagtg ggaaaacaac gattttaaat ttaattaatg
     1981 gttctttaaa gccacaaaaa ggttatgtaa atttgttatc acatgggaaa aagagttcag
     2041 attcaatacc aacagttgat cagacaccat atatttttga cactactatt cgtgagaacg
     2101 taactttatt tcaaaatgaa tatttttcag atgatcagat aattgaggtg ttaaaaaagg
     2161 taaatctata tgaagaatta gaaaagatag atatactaaa ttatcaatgt ggtgaaaatg
     2221 gtagtaattt gtctggaggt caaaaacaaa aaatagcttt agctagagct ctgattagaa
     2281 ataataaagt gtacttattt gacgaaatat cagctaattt agataatgat aattcaaatt
     2341 ccatacatga tattctgttc aatttaggta tttcatttat tgaagtttca catcattatg
     2401 acttaaatga caagagatac actgatatat aaattggaaa atggaacact tttcaaaatt
     2461 aagtgattgg aggcaagaat atggataaag attatatatt aaaagtgaaa gggctgtatc
     2521 atcaattttt actgggaaac aataaaacgt tgcaagtgct gaaaaatgtt tctctttctg
     2581 cttcgagagg agaatttata agtattctag gaattagtgg ttctggaaag tcaactttat
     2641 taaaatgtat ttctagtttg cttgaaccaa caagtgggga agtaatttta aatggaatca
     2701 acccctataa aatcagaaat gcaaaattgt caagtataag acgtaacgaa gtatctttta
     2761 tatttcaagc atacaattta ataccttccc tgccggtaat agaaaatata gcacttcctt
     2821 tgcgattatc acaaaaaaaa ttaactatta aaaatgtaga aaacttactc aaaagaatga
     2881 agtttaatgc tggcttaaac gattttgttg gaactctgtc tggtggagaa caacagaagg
     2941 ttgctatagc tagagcggtt attgctgata gtgatataat atttgctgat gagccaactg
     3001 gggctttaga cagcgtttct cgtgaagtaa tttttgaatt attgagagag ttagtagggg
     3061 cgggtaagtg tgtaattatg gtaacgcacg atatagaatt ggcctcgaaa actgatcgtg
     3121 cattaatatt gaaagatgga aaaattttca aagaacttca tagacctagc ggggaagagt
     3181 tgtataaaat cttagaggta caatcaacta cggaggaata gagatgctca gattagttta
     3241 ctatcaattt ttacataata agaaacaatg gttaggcgtt tcaccagtaa tttttgtttc
     3301 gagtttagtt atgggattgg ctgttaatgg ggtaattaat gttgagaata attcgcaagt
     3361 atttgtcgga cttccagatc ctaaaccaat ttttatgttt ccgatagtat tcggaggagt
     3421 aacattattc tttgtgctct ctaacataat aaatatgttg gttgaaattt ttagagatga
     3481 ttacgaactt ctggaggtgt tgggagcaag tctccttcaa ctatcatttc ttgtgggggg
     3541 acagattttt atcatttcct cgattattag ttttattgca tatctatgct ctatatttgt
     3601 tacgtcaaat tattattatt ttttacaata ctttttcggg gaaaatatat tacctgatat
     3661 ccaatttcaa acgagtgctg ttggatgtat cattacagta gtgttgattt catttttagc
     3721 ctttctaagt ggttgctttt atacgttcaa gaagattaga aataggaaga gttctaaaat
     3781 aaggcatgtt ctttcaatag taaaaagaat actgctattg gctggtttta gtgttatctg
     3841 gttgctttct ttgcaacaaa ttttccaaga tagcacaatt ttagcgaagg cccagataat
     3901 attcaatatt gtaatcttag atattgtgat tatttatcaa ttatctcctt ttatacagtc
     3961 atgttttatc aaactacttt ctataattat atttagaaat aattttatgt tcattgtttc
     4021 gaagtggaat ttactatatc gtaagcctta tataaaatct atcagtgctg caattacagg
     4081 agctatatta ctaatttcta gttttcaaat gatttctcag aatatactat ctcaatttca
     4141 agatgacagt gatttagagc taaaagtggc atttattgtc tatgtaggag caccaatttt
     4201 gatagtactt gcaaatatta tttcaattgc atttttgtca tcgcatcaag aaaggattga
     4261 gattcagcaa tttgaaattt taggaacttc taattaccag atggttaaga ttaaagttgg
     4321 tgaggctata tttttgacat ttgttacttc attaattgca tttttactta acattaaa
//
LOCUS       DBEJKC010000091         4223 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.091, whole genome shotgun sequence.
ACCESSION   DBEJKC010000091 DBEJKC010000000
VERSION     DBEJKC010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4223
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.091"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..664
                     /locus_tag="ACL3G6_001963"
     CDS             <1..664
                     /locus_tag="ACL3G6_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0546428.1"
                     /translation="DYVLKGINVTIKKGETVAIVGESGSGKSTLAKILLGLLEPNIGS
                     IEVDGVEKEEIGQTLYRKIFGAVLQNSTLSYGTLRENLTFGHFVSDEELMTNLNSIGL
                     SNVVKSLPLGLETIIAEEGNNFSGGQQQMILLARCLLSKPSVVVLDEATSSLDNLSQQ
                     ITTSYLSEIGTTKILIAHRLDTIKSADKILVMHNGEIVEIGTHRELLELGGIYKQLYS
                     NN"
     gene            688..2427
                     /locus_tag="ACL3G6_001964"
     CDS             688..2427
                     /locus_tag="ACL3G6_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGR0546429.1"
                     /translation="MKIMKKKYWTLAILFFCLFNNSVTAQEIPKNLDGNITHTQTSES
                     FSESDEKQVDYSNKNQEEVDQNKFRIQIDKTELFVTTDKHLEKNCCKLELEPQINNDI
                     VNSESNNLLGEDNLDNKIKENVSHLDNRGGNIEHDKDNLESSIVRKYEWDIDKVTGGG
                     ESYKLYSKSNSKVSIAILDSGVDLQNTGLLKNLSNHSKNYVPNKGYLGKEEGEEGIIS
                     DIQDRLGHGTAVVAQIVGDNNINGVNPHVNINVYRIFGKSSASPDWIVKAIFDAVDDG
                     NDIINLSTGQYLMIDGEYEDGTNDFETFLKYKKAIDYANQKGVIIVAALGNDSLNVSN
                     QSDLLKLISSRKKVRKPGLVVDVPSYFSSTISVGGIDRLGNLSDFSNKGDSDAIYAPA
                     GSTLSLSELGLNNFINAEKYKEDWIFSATLGGYTYLYGNSFAAPKVSGAIAMIIDKYK
                     LKDQPYNYMFVKKILEETLPVKNGIKVLNIPNVLRYDLNMLQLEYKNEQSWDSFIDNV
                     NLIELEERIQTTIGIKQINTHNIITIAREGYSQNYLPNTSENTYNSLQVSLVGVLLLF
                     ISMVNILWAKKSK"
     gene            2478..3245
                     /locus_tag="ACL3G6_001965"
     CDS             2478..3245
                     /locus_tag="ACL3G6_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HGR0546430.1"
                     /translation="MSQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRISSQD
                     ERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQSILFWIDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVE
                     IGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            3247..3879
                     /locus_tag="ACL3G6_001966"
     CDS             3247..3879
                     /locus_tag="ACL3G6_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0546431.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
BASE COUNT         1488 a          599 c          806 g         1330 t
ORIGIN      
        1 tgattatgtt ttgaaaggaa taaatgttac tattaaaaaa ggagaaactg ttgctattgt
       61 tggagaatca ggttcaggta agagtacatt agctaaaatt ttattaggtt tattagaacc
      121 taatattggt tcaatagaag ttgatggagt agaaaaagaa gaaattggtc aaacattgta
      181 tagaaagatt tttggagcag tgttacaaaa ttcaacccta agttatggta ccttaagaga
      241 gaatttgaca tttggacact ttgtttcaga tgaagaatta atgacaaatc taaattcaat
      301 tggtcttagc aatgtagtta aatctttacc tcttggatta gagacaatca tcgctgaaga
      361 aggtaataac ttttctggag ggcagcagca aatgatactt ttagctcgtt gtcttttgtc
      421 gaaaccttcg gtagttgttt tggacgaagc aacaagtagt ttagataatt tatctcaaca
      481 aattacaact tcttacttaa gtgaaatcgg taccactaag attttaattg cccatcgact
      541 agatactatc aagtctgcag ataagatctt agtaatgcat aatggtgaaa ttgtagagat
      601 tgggacccat agagaacttc ttgaactagg aggcatttat aagcaattgt attcaaataa
      661 ttagtttttg attaaaaggg taaatttatg aagattatga aaaaaaaata ttggacttta
      721 gcgatattat tcttttgttt gttcaataat tctgttactg ctcaagaaat acctaaaaat
      781 cttgatggca atataactca cactcagact agcgaaagtt tttctgaatc tgatgaaaaa
      841 caggttgact attctaataa aaatcaagaa gaagtagacc aaaataaatt tcgtattcaa
      901 atcgataaga cagaattatt tgtaacaaca gataaacatt tagaaaaaaa ctgttgtaaa
      961 ttggaacttg aaccacaaat aaataacgat attgttaact ctgaaagtaa taatttacta
     1021 ggcgaagata atttagataa taaaattaag gaaaatgttt ctcatctaga taatagagga
     1081 ggaaatatag agcatgacaa agataactta gaatcgtcga ttgtaagaaa atatgaatgg
     1141 gatatagata aagttactgg tggaggcgaa agttataaat tatattctaa aagtaattct
     1201 aaagtttcaa ttgctatttt agattcagga gtcgatttac aaaatactgg attactgaaa
     1261 aatctttcaa atcactcaaa aaactatgtc cccaataaag gatatttagg aaaagaggag
     1321 ggagaggaag gaataatatc agatattcaa gatagattag gtcatggtac ggctgttgta
     1381 gctcaaattg taggggataa caatattaat ggagtaaatc ctcacgttaa tattaacgtc
     1441 tatagaatat ttggtaagtc gtcagctagt ccagattgga ttgtaaaagc aatttttgat
     1501 gctgtagatg atggcaatga tattatcaat cttagtactg gacaatattt aatgattgat
     1561 ggagaatatg aggacggaac aaatgatttt gaaacatttt tgaagtataa aaaggctatt
     1621 gattacgcga atcaaaaagg agtaattata gtagctgcat tagggaatga ctccctaaat
     1681 gtatcaaatc agtcagattt attgaaactt attagttcac gcaaaaaagt aagaaaacca
     1741 ggattagtag ttgatgttcc aagttatttc tcatctacaa tttcggtcgg aggcatagat
     1801 cgcttaggta atttatcaga ttttagcaat aaaggggatt ctgatgcaat atatgcgcct
     1861 gcaggctcaa cattatctct ttcagaatta ggacttaata actttattaa tgcagaaaaa
     1921 tataaagaag attggatttt ttcggcaaca ctaggaggat atacgtatct ttatggaaac
     1981 tcatttgctg ctcctaaagt ttctggtgcg attgcaatga ttattgataa atacaaatta
     2041 aaagatcagc cctataatta tatgtttgta aaaaaaattc tggaagaaac attaccagta
     2101 aaaaatggta taaaagtgtt aaatatacca aacgtattga gatatgattt gaatatgtta
     2161 caattagaat ataaaaatga acaaagttgg gatagtttca tagataatgt taatttaatt
     2221 gagttggaag agagaattca aactactatt ggaattaaac aaataaacac acacaatatt
     2281 attactattg cccgagaagg gtactctcaa aattatttac ctaacacttc agaaaataca
     2341 tataattcat tacaagtcag tttagttgga gtattactac tttttataag tatggtaaat
     2401 attttatggg ctaaaaaaag taaatgaaaa taaaatttgg agccctctga aaaagtaagt
     2461 cctacagttc aactaaaatg agtcaaaaga tgaatcacct tgatgtaggg gagtttgtct
     2521 tattgctgcc tgaacacctc cgttcagagg aagaacatta taaatctgtt tttgaagacg
     2581 acttaaccag tcgcatatct agtcaagatg aacgacagca aatgactgct acggtaggtt
     2641 atttagaatc aggtcaggat cgttttgtgt ataatacgac ccctatttct taccagcagt
     2701 ttttgaaaga tccaatcatc attgttataa caccccaatc aactggtcca cagtccattt
     2761 tgttttggat agacgcagta cagaactacg ttctctttaa tcaattgtct gatgcccagg
     2821 agcttatcca gagacaaggc attgaaaatt gggtctcaga aatgcaaaca ggttaccaca
     2881 actacatcac attattggat aatatccaga gggaacgttg ggtaatgcta gcaggagctg
     2941 tgcttgggat tgcaacttca atcttgttgt ttaacactat gaataggctc tactttgaag
     3001 aatttagacg tgccattttt atcaaacgca ttgcaggtct caggttctta gaaatccatc
     3061 gcacttatct ctttgctcaa ctgggtgtgt ttttactggg atttgttgcg agtgtatttc
     3121 ttcaggtaga gataggagtt gctttcttag tcttgttact ctttactggt ctatctcttt
     3181 tacagttaca tgtccaaatg cagaaagaaa acaagatgtc cattcttgtt ttgaagggag
     3241 gttaatatga ttgaacttaa acaggtgagt aaatcttttg gagaacgaga gttattttcg
     3301 aatctttcaa tgacatttga ggctggaaaa gtctatgcct taattggttc aagtggtagc
     3361 ggaaaaacaa ccttgatgaa catgattggg aaattagaac cttatgatgg gacgattttt
     3421 taccgaggta aagacttggc caattataaa tcgagtgatt ttttccgtca cgaattgggc
     3481 tacctcttcc agaactttgg cttaattgaa aaccaaagta ttgaagaaaa ccttaagcta
     3541 ggtctcattg gtcaaaagtt gagtcggtcg gaacagcggt tgaggcagaa gcaggcttta
     3601 gaacaggtcg gcctggctta tcttgaccta gataagcgca tctttgagtt atcgggcgga
     3661 gaatcgcaac gggttgcctt ggcaaaaatt atcttaaaga atccaccctt tattctggca
     3721 gatgagccaa cagcttcaat agacccagca acctctcagt tgattatgga gattttgcta
     3781 tctcttcgag atgataatag gctaatcatt atcgcaacac ataatccggc aatttgggag
     3841 atggctgatg aagtgttcac gatggatcat ctgaaataaa aatccttgtt tttaattgca
     3901 cgatgagtta ctgaaatatt atcatgaatc aagaattgga gttaatttag aattgtactt
     3961 tattaatatt gaggtaactt tttcttgata aaggaagaaa taatggagag gaagttagaa
     4021 tgaaaaaatt cgacaattat attattgaga agccttgcga ttctaattca gataaactgc
     4081 aaaaaatctt aataattgaa agtttggtag atgatatttt gcaattttct ctcagaatca
     4141 ataatagtgt aggagagatt ttcctcctac aaccgtttta aaagaaaact atctttatcc
     4201 caaatcattc atacctctct caa
//
LOCUS       DBEJKC010000092         4185 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.092, whole genome shotgun sequence.
ACCESSION   DBEJKC010000092 DBEJKC010000000
VERSION     DBEJKC010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4185
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.092"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            74..319
                     /locus_tag="ACL3G6_001967"
     CDS             74..319
                     /locus_tag="ACL3G6_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546432.1"
                     /translation="MKAFYITIEKFIRDDESLKCYFIKVISSRSKVTSLDQIEADKTI
                     QRKYSSELKKFIGFYNEIICEENSFLHVRKRWSSWFR"
     gene            720..1712
                     /locus_tag="ACL3G6_001968"
     CDS             720..1712
                     /locus_tag="ACL3G6_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0546433.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="ACL3G6_001969"
     CDS             1714..2532
                     /locus_tag="ACL3G6_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0546434.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="ACL3G6_001970"
     CDS             2534..3319
                     /locus_tag="ACL3G6_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0546435.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3417..3635
                     /locus_tag="ACL3G6_001971"
     CDS             3417..3635
                     /locus_tag="ACL3G6_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HGR0546436.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3620..3817
                     /locus_tag="ACL3G6_001972"
     CDS             3620..3817
                     /locus_tag="ACL3G6_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0546437.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEASNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNPQNPCQILIKKLE"
BASE COUNT         1161 a          719 c          907 g         1398 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gaatgataaa attaatcaat tgatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta taaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cgatgcgtga gttgataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tattttatga
      541 gagaaatcct aatttcacaa tccataggca aactcttgca tttcgttttt tattggacta
      601 taataggttg gtataaagcc ttttgtagta ataaaatgta gaaggtgtag aaagcaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aaaattttgt gaagactgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccaggaca atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccaaact cgctctttca taagcgcatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg ggcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agatcaatca agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca agagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctcgtctct cactatgaag gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc
     1621 aaaccctgtc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccattttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta
     2161 actgtccttt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc ggggagtttg attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tttccttttt gcctttttca tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttgatt tggaaacggg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ctggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggggagtt
     2821 tgacaagtat ttgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccaa aattcctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagc tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatgtt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagga acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaggc agttgtcgct gaggttttga
     3421 aggatttgcc agaatggttt ggaatcccag aaagcacaca agcctatata gaaggaacca
     3481 cgacactgca agtttggacc gcctatcagg agagtgattt gactggattt gtaaggttat
     3541 cctattcgag tgaagattgt gcagagattg attgtctcgg cgtaaaaaag cttatcaagg
     3601 tagaaaaatt gggagccaat tgcttgctac tttagagagt gaagctcgta aaaaagttgg
     3661 ttatctgcag gtcaaaacag tggcagaagc ttctaataaa gattatgatc gaacaaatga
     3721 cttttatcga ggtcttggct ttaaaaagtt agagattttt tctcagctat ggaatccgca
     3781 aaatccttgt cagattttga ttaaaaagct tgaataatat tacttgacat ctattctcag
     3841 agtgccatac tgtaagtgta atcgccgatt tagctcagtt ggtagagcaa ggcactcgta
     3901 aagcctaggt tataggtaga taaacgactg aggagttgaa aaaatagata ggtagaagat
     3961 aaccgttaag ccttattctt agcggttatt tatattattt aatagcgctg atatttcatc
     4021 aattatgcct gttttcgtgt ttctggtagt tgttcaagtt tattgctact atttttgatg
     4081 gtatgaatgt gcttataatg tatcccggtt aacgaaagtt ttggacttat actcttcgaa
     4141 aatctcttca aaccacgtca acgtcgcctt gccgtgcgta tggtt
//
LOCUS       DBEJKC010000093         4038 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.093, whole genome shotgun sequence.
ACCESSION   DBEJKC010000093 DBEJKC010000000
VERSION     DBEJKC010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4038
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.093"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(3..1826)
                     /locus_tag="ACL3G6_001973"
     CDS             complement(3..1826)
                     /locus_tag="ACL3G6_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002917262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1250 family conjugative relaxase"
                     /protein_id="HGR0546438.1"
                     /translation="MVITKHFAIHGKSYRRKLIKYILNPEKTNNLALVSDYGMKNFLD
                     FPSYEEMVQMYHENFISNDTLYDFRHDRMEENQRKIHAHHIIQSFSPEDHLTPEQINR
                     IGYETVKELTGGKFRFIVATHVDKDHLHNHIIINSVDSNSDKKLKWDYKVERNLRMIS
                     DRFSKIAGAKIIENRYSHQRYEVYRKTNHKYELKQRLYFLMEHSRDFEDFKKNAPLLH
                     VEMDFRHKHATFFITDSTMKQVVRGKQLNRKQPYTEEFFKNYFAKREIESLMEFLLLK
                     VENMDDLLQKAKLFGLTINPKQKHVSFQFAGVEVKETELDQKNLYDVEFFQDYFKNRK
                     DWQAPETEDFVQLYQEEKLSKEKELPSDEKFWESYQEFKSNRDAVHEFEVELSLNQIE
                     KVVDDGIYVKVKFGIRQEGLIFVPNMQLDMEEDKVKVFIRETSSYYVYHKDAAEKNCY
                     MKGRTLIRQFSYENQTIPLRRKATVDMIKEKIAEVDALIELEVENQSYVTIKDELVHE
                     LAASELRINELQERMSTLNQVAEYLLASVESKQEMKLNLSKLNITENISANIVEKKLK
                     SLGNQLELERGRYEKMVVRLDKFINRLNTGLSKGDGIDFQK"
     gene            complement(1813..2178)
                     /locus_tag="ACL3G6_001974"
     CDS             complement(1813..2178)
                     /locus_tag="ACL3G6_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HGR0546439.1"
                     /translation="MEHRYRTNLKKVFLSDSELNQLNINIDQSGCKSFSEYARRTLLD
                     PGMNFITIDTNGYQDLVFELKRIGNNINQIARSVNQSQLIPGEELQELKKGIGELIKE
                     VDKEFNLQAQKLKEFHGHH"
     gene            complement(2183..2539)
                     /locus_tag="ACL3G6_001975"
     CDS             complement(2183..2539)
                     /locus_tag="ACL3G6_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1252 family conjugative relaxosome accessory
                     protein"
                     /protein_id="HGR0546440.1"
                     /translation="MKRDVRDIRKQFRLTEAEEKQILALMRERGETNFSDFLRKSLLS
                     SDLQKQMETWFALWQSQKLEQISRDVHEVLILAQSERQVTQEHVSILLTCVQELIQEV
                     ANTIPLSKEFREKYMR"
     gene            2901..>4038
                     /locus_tag="ACL3G6_001976"
     CDS             2901..>4038
                     /locus_tag="ACL3G6_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGR0546441.1"
                     /translation="MLSLDQIHLLLNTPEDEFHDFKQKWHHSKTELVRDILNFVNTSH
                     HEDCYIIFGIDNITLDIIGVNNDDNRRNEEDLTDLLHKLFISTNNQIKISIQTETIDN
                     KEIDILIIHDTDKVPVFLTKDYKPKKDTALPKGLIYAINGSINTPKDSSAPFELINEL
                     FQKFNHTDLNIKEQYFHVLKDYKNWFFIENEDGRFFIYNPNPDFYIKLNDDDANRFKT
                     MSYSLNQYQTNIDWQLVQLRYRHLTIDECMAMYLDQGNCLVPSPEVESFKIDYQETIY
                     YHCLYKNTLKYQLLKVFSSIPGLEKYPLTRFKNSIVIYDTKLELKKTHNLINSKFSSK
                     DIVNQLEVTEKDFDFYYKKARHKNPDYSIQENQVNLTELNLVRLL"
BASE COUNT         1265 a          775 c          629 g         1369 t
ORIGIN      
        1 tcctattttt gaaaatctat cccatctcct tttgaaagtc ctgtatttaa gcgatttata
       61 aatttatcta gcctgactac catcttttca tacctgcccc tttccaattc cagttgattc
      121 cccaggctct tcaatttttt ctcaacaata ttagcactga tattctcagt tatattcagt
      181 tttgaaagat ttaatttcat ttcttgctta ctttcaactg aagccagtag atattctgct
      241 acttgattca aggttgacat tcgttcttgc aactcattga ttcttaattc agacgctgct
      301 agttcatgca ctaactcatc tttaatcgtg acataagatt gattttctac ttccagttca
      361 atcaaagcat ccacttccgc aatcttctct ttaatcatat cgactgtcgc ttttctgcgt
      421 aatggaatgg tttgattttc atagctgaac tgtctaatta aggttcgacc tttcatataa
      481 caatttttct cggcagcgtc tttgtggtag acatagtagg agctggtttc cctgatgaaa
      541 accttcacct tatcctcttc catatcaagc tgcatgttcg gcacaaagat aagtccctcc
      601 tgacgaatac caaacttgac cttgacgtaa attccatcat ccactacttt ttcaatttga
      661 ttgagtgaca actccacctc aaattcatga acggcatctc tgttactctt gaactcttga
      721 taggactccc agaacttctc atcgcttgga agttcttttt ctttggataa cttttcttct
      781 tgataaagtt gaacgaaatc ctcagtttct ggagcttgcc aatcttttct atttttaaaa
      841 taatcttgga aaaactctac atcataaaga tttttctggt ctagctctgt ctcctttacc
      901 tccactcctg caaattgaaa agaaacatgc ttttgtttag gattgatagt tagtccaaaa
      961 agttttgctt tctgaagtaa atcatccata ttctcaactt tcagcaataa aaattccatg
     1021 agactttcta tttctctttt ggcaaagtag ttcttaaaaa attcttctgt gtaaggctgc
     1081 ttgcgattga gttgcttgcc acgcaccacc tgtttcatag ttgagtccgt aataaaaaag
     1141 gtggcatgct tgtgacggaa atccatctcc acatgtagta gcggagcatt ctttttgaaa
     1201 tcctcaaagt ccctagaatg ttccatcaaa aaatagagtc gctgcttgag ttcatacttg
     1261 tgattagtct tacgatagac ttcataccgc tggtgagaat agcggttctc aatgatttta
     1321 gcacctgcga ttttagaaaa acggtcagaa atcatgcgaa gatttcgctc caccttgtag
     1381 tcccacttga gctttttgtc agaattgcta tctactgaat tgataatgat gtgattgtgc
     1441 aggtggtctt tatcaacatg ggtcgcaacg ataaaacgaa atttgccacc agttaattcc
     1501 ttcacagtct cataacctat ccgattgatt tgttcaggag tgagatgatc ctctggcgag
     1561 aaagactgaa tgatgtggtg agcgtgtatt tttcgttgat tttcttccat cctgtcgtgg
     1621 cgaaaatcgt aaagcgtatc gttgctgatg aaattttcat gatacatctg caccatttcc
     1681 tcatagctag gaaagtccag aaaattcttc atgccatagt ccgacaccaa ggcaagatta
     1741 ttggttttct caggattgag aatgtacttg ataagctttc tgcggtaact ctttccgtga
     1801 atggcaaagt gtttagtgat gaccatggaa ctcctttagc ttctgcgctt gcagattaaa
     1861 ttccttatca acttctttta tcaattcacc aattcctttt ttcaactcct gcaattcttc
     1921 accaggaatt aactgagatt gattaacact tcgagcaatc tggttgatat tattgccaat
     1981 cctctttaac tcaaacacta aatcttggta accgtttgtg tcaatcgtga taaaattcat
     2041 accaggatcg agtagagttc gtctcgcata ttcagaaaag gatttacaac cactttgatc
     2101 gatatttata tttagttggt tcaactcact atcagacaaa aacactttct tgagattggt
     2161 tcggtaacga tgttccatgt gcttacctca tgtacttctc acgaaattct ttactgaggg
     2221 gtatggtgtt tgcaacctct tgaatcaatt cctgcacgca cgttaagaga atagatacat
     2281 gctcttgggt gacttgacgt tctgactgtg ccaagattaa aacttcatga acgtcacgac
     2341 tgatttgttc tagtttttgg gattgccaga gggcaaacca tgtctccatc tgtttttgta
     2401 aatcagagga aagtaaactt ttacgaagaa aatcagagaa attagtctct ccccgctctc
     2461 tcatcaaagc tagaatttgc ttttcttctg cttctgttaa acgaaattgt ttccgaatat
     2521 cacgcacatc tcgtttcata ctgctacttc ctttccaaaa tacttgtact gacaatgtga
     2581 gctaccatac aatgtcagta cacttttcca acaactgatt ttcattcttg taaggctttg
     2641 cgagctcaga tattgtgtcc acaatatctc aaaaatcata tcgccagcct atcaaaactt
     2701 tctagttttg acagccaacg ataagataac ttggtgactt cgcccccaaa cccccataga
     2761 aaatcaaaaa ttgattttct atgaatgata ttaggataac agggaagatt tgaaaaaggt
     2821 atcacagcta atatagttat gattgacttt ctctgattct atgataaaat ttctgtaaac
     2881 taatatttgg agaaataaaa atgctgagtc tagatcaaat acacttacta ttgaatacac
     2941 ccgaagatga gtttcatgat tttaaacaaa aatggcatca ttcaaaaact gaattggtgc
     3001 gtgatatctt aaattttgtc aatacatcac atcacgaaga ttgttatatc atctttggaa
     3061 ttgataatat cactttagat ataatcggtg taaacaatga tgataataga agaaatgaag
     3121 aagatctaac agatttacta cataaactct ttatatcaac aaataatcaa attaaaatta
     3181 gcatacaaac tgaaactata gacaacaaag aaattgacat cttaattatt catgatacag
     3241 ataaagttcc tgtattttta acaaaagatt ataagcctaa gaaagatact gcattaccaa
     3301 aaggattaat atatgctata aatggctcta taaatacccc taaagactcc tctgctcctt
     3361 ttgagttaat aaatgagttg tttcaaaagt ttaatcatac cgacttaaat atcaaagagc
     3421 agtattttca tgttttaaaa gactataaaa attggttctt cattgaaaat gaagacggaa
     3481 gattttttat ttataatcct aatcccgatt tttatattaa acttaacgac gatgatgcaa
     3541 atcgtttcaa aactatgtct tatagtttaa atcaatacca gactaatatt gattggcaat
     3601 tagtacaact tcgatatcgt catcttacaa ttgacgagtg tatggctatg tatttagatc
     3661 aaggtaattg tctagtccct tcccctgaag tagaaagttt taaaatagat tatcaggaga
     3721 ctatttatta tcactgctta tacaaaaata ctttaaagta ccaattgctg aaagtatttt
     3781 cttcaatacc tggtctcgaa aaatatcctt taactagatt taaaaatagt atagtaattt
     3841 atgacacaaa attagaattg aaaaagactc acaacttgat aaatagtaaa ttctcatcaa
     3901 aagacatagt gaatcaactt gaagttacag aaaaagattt cgatttttac tataaaaaag
     3961 ctagacataa aaatcctgat tatagcatcc aagaaaatca agtaaatcta actgaattaa
     4021 acttagttag gttattga
//
LOCUS       DBEJKC010000094         3934 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.094, whole genome shotgun sequence.
ACCESSION   DBEJKC010000094 DBEJKC010000000
VERSION     DBEJKC010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3934
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.094"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            371..598
                     /locus_tag="ACL3G6_001977"
     CDS             371..598
                     /locus_tag="ACL3G6_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546442.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3783
                     /gene="nanA"
                     /locus_tag="ACL3G6_001978"
     CDS             886..3783
                     /gene="nanA"
                     /locus_tag="ACL3G6_001978"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HGR0546443.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTPE
                     LPKGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLDGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPKRENGMVHLARVEENGELTWIKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1343 a          657 c          868 g         1066 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaataaggta taataaattt
      241 actaacactt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtataaatag cataagctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaaattggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgccaagg ctccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacaataa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acaccagaac tacctaaagg ccgagtgcgc
     1561 ctctacgtaa acggggtatt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt acaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattcg gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tctatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aaaaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga aggagaaaag ggagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtgaccaat tactaggcaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttagatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 agacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcataatgg aaaagaatac attatcctca gcaatgcagg tggaccgaaa
     3001 cgtgaaaatg ggatggtcca cttggctcgt gtcgaagaaa atggtgagtt gacttggatc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gcatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga ctttttgagc aaagatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gagatgggca aaggagttat tggcttggag
     3301 ttcgactcag aagtattggt caacaaggct ccaacccttc aattggcaaa tggtaaaaca
     3361 gcgactttcc taacccagta tgatagcaag accttgttat ttgcagtaga taaggaagat
     3421 atcggacagg aaattattgg tatagctaaa ggaagcatcg aaagtatgca taatcttcct
     3481 gtaaatctag caggtgccag agttcctggc ggagtaaatg gtagcaaagc agcggtgcat
     3541 gaagttccag aatttacagg gggagttaat ggtacagagc cagctgttca tgaaatcgca
     3601 gagtataagg gatctgattc gcttgtaact cttactacaa aagaagatta tacttacaaa
     3661 gctcctcttg ctcagcaggc acttcctgaa acaggaaaca aggagagtga cctcctagct
     3721 tcactaggac taacagcttt cttccttggt ctgtttacgc tagggaaaaa gagagaacaa
     3781 taagagaaga attctaaaca tttgattttg taaaaataga aggagatagc aggttttcaa
     3841 gcctgctatc tttttttgat gacattcagg ctgatacgaa atcataagag gtctgaaact
     3901 actttcagag tagtctgttc tataaaatat agta
//
LOCUS       DBEJKC010000095         3878 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.095, whole genome shotgun sequence.
ACCESSION   DBEJKC010000095 DBEJKC010000000
VERSION     DBEJKC010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3878
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.095"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..429
                     /locus_tag="ACL3G6_001979"
     CDS             <1..429
                     /locus_tag="ACL3G6_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HGR0546444.1"
                     /translation="DHVRKNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSA
                     DNLYKPSTDTEETEEEAEDTTDETEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAM
                     ETLTGLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
     gene            639..3758
                     /gene="phtE"
                     /locus_tag="ACL3G6_001980"
     CDS             639..3758
                     /gene="phtE"
                     /locus_tag="ACL3G6_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HGR0546445.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNLADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1452 a          631 c          757 g         1038 t
ORIGIN      
        1 gaccatgttc gtaaaaataa ggcagaccaa gacagtaaac ctgatgaaga taagggacat
       61 gatgaagtaa gtgagccaac tcaccctgaa tctgatgaaa aagagaatca cgctggttta
      121 aatccttcag cagataatct ttataaacca agcactgata cggaagagac agaggaagaa
      181 gctgaagata ctacagatga gactgaaatt cctcaagtag agcattctgt gattaacgct
      241 aagatagcag aggcggaggc cttgctagaa aaagtaacag attctagtat tagacaaaat
      301 gctatggaga cattgactgg tctaaaaagt agtcttcttc tcggaacgaa agataataac
      361 actatttcag cagaagtaga tagtctcttg gctttgttaa aaaaaagtca accggctccg
      421 atacagtagt aaaatgaatg gagcatattt tatggagaag taacctttcg tgttacttct
      481 cttttttaga aaaacgtaac agaaacttga caaaagtaat tttaaatagt aaactattta
      541 ctggttaatt aaatggttaa ataaccggtt tagaaaacta tttaataaag taaaagaagt
      601 tgagaaaaaa cttcatcatt tattgaaatg agggatttat gaaatttagt aaaaaatata
      661 tagcagctgg atcagctgtt atcgtatcct tgagtctatg tgcctatgca ctaaaccagc
      721 atcgttcgca ggaaaataag gacaataatc gtgtctctta tgtggatggc agccagtcaa
      781 gtcagaaaag tgaaaacttg acaccagacc aggttagcca gaaagaagga attcaggctg
      841 agcaaattgt aatcaaaatt acagatcagg gctatgtaac gtcacacggt gaccactatc
      901 attactataa tgggaaagtt ccttatgatg ccctctttag tgaagaactc ttgatgaagg
      961 atccaaacta tcaacttaaa gacgctgata ttgtcaatga agtcaagggt ggttatatca
     1021 tcaaggtcga tggaaaatat tatgtctacc tgaaagatgc agctcatgct gataatgttc
     1081 gaactaaaga tgaaatcaat cgtcaaaaac aagaacatgt caaagataat gagaaggtta
     1141 actctaatgt tgctgtagca aggtctcagg gacgatatac gacaaatgat ggttatgtct
     1201 ttaatctagc tgatattatc gaagatacgg gtaatgctta tatcgttcct catggaggtc
     1261 actatcacta cattcccaaa agcgatttat ctgctagtga attagcagca gctaaagcac
     1321 atctggctgg aaaaaatatg caaccgagtc agttaagcta ttcttcaaca gctagtgaca
     1381 ataacacgca atctgtagca aaaggatcaa ctagcaagcc agcaaataaa tctgaaaatc
     1441 tccagagtct tttgaaggaa ctctatgatt cacctagcgc ccaacgttac agtgaatcag
     1501 atggcctggt ctttgaccct gctaagatta tcagtcgtac accaaatgga gttgcgattc
     1561 cgcatggcga ccattaccac tttattcctt acagcaagct ttctgcctta gaagaaaaga
     1621 ttgccagaat ggtgcctatc agtggaactg gttctacagt ttctacaaat gcaaaaccta
     1681 atgaagtagt gtctagtcta ggcagtcttt caagcaatcc ttcttcttta acgacaagta
     1741 aggagctctc ttcagcatct gatggttata tttttaatcc aaaagatatc gttgaagaaa
     1801 cggctacagc ttatattgta agacatggtg atcatttcca ttacattcca aaatcaaatc
     1861 aaattgggca accgactctt ccaaacaata gtctagcaac accttctcca tctcttccaa
     1921 tcaatccagg aacttcacat gagaaacatg aagaagatgg atacggattt gatgctaatc
     1981 gtattatcgc tgaagatgaa tcaggttttg tcatgagtca cggagaccac aatcattatt
     2041 tcttcaagaa ggacttgaca gaagagcaaa ttaaggctgc gcaaaaacat ttagaggaag
     2101 ttaaaactag tcataatgga ttagattctt tgtcatctca tgaacaggat tatccaagta
     2161 atgccaaaga aatgaaagat ttagataaaa aaatcgaaga aaaaattgct ggcattatga
     2221 aacaatatgg tgtcaaacgt gaaagtattg tcgtgaataa agaaaaaaat gcgattattt
     2281 atccgcatgg agatcaccat catgcagatc cgattgatga acataaaccg gttggaattg
     2341 gtcattctca cagtaactat gaactgttta aacccgaaga aggagttgct aaaaaagaag
     2401 ggaataaagt ttatactgga gaagaattaa cgaatgttgt taatttgtta aaaaatagta
     2461 cgtttaataa tcaaaacttt actctagcca atggtcaaaa acgcgtttct tttagttttc
     2521 cgcctgaatt ggagaaaaaa ttaggtatca atatgctagt aaaattaata acaccagatg
     2581 gaaaagtatt ggagaaagta tctggtaaag tatttggaga aggagtaggg aatattgcaa
     2641 actttgaatt agatcaacct tatttaccag gacaaacatt taagtatact atcgcttcaa
     2701 aagattatcc agaagtaagt tatgatggta catttacagt tccaacctct ttagcttaca
     2761 aaatggccag tcaaacgatt ttctatcctt tccatgcagg ggatacttat ttaagagtga
     2821 accctcaatt tgcagtgcct aaaggaactg atgctttagt cagagtgttt gatgaatttc
     2881 atggaaatgc ttatttagaa aataactata aagttggtga aattaaatta ccgattccga
     2941 aattaaacca aggaacaacc agaacggccg gaaataaaat tcctgtaacc ttcatggcaa
     3001 atgcttattt ggacaatcaa tcgacttata ttgtggaagt acctatcttg gaaaaagaaa
     3061 atcaaactga taaaccaagt attctaccac aatttaaaag gaataaagca caagaaaact
     3121 caaaacttga tgaaaaggta gaagaaccaa agactagtga gaaggtagaa aaagaaaaac
     3181 tttctgaaac tgggaatagt actagtaatt caacgttaga agaagttcct acagtggatc
     3241 ctgtacaaga aaaagtagca aaatttgctg aaagttatgg gatgaagcta gaaaatgtct
     3301 tgtttaatat ggacggaaca attgaattat atttaccatc gggagaagtc attaaaaaga
     3361 atatggcaga ttttacagga gaagcacctc aaggaaatgg tgaaaataaa ccatctgaaa
     3421 atggaaaagt atctactgga acagttgaga accaaccaac agaaaataaa ccagcagatt
     3481 ctttaccaga ggcaccaaac gaaaaacctg taaaaccaga aaactcaacg gataatggaa
     3541 tgttgaatcc agaagggaat gtggggagtg accctatgtt agatccagca ttagaggaag
     3601 ctccagcagt agatcctgta caagaaaaat tagaaaaatt tacagctagt tacggattag
     3661 gtttagatag tgttatattc aatatggatg gaacgattga attaagattg ccaagtggag
     3721 aagtgataaa aaagaattta tctgatctca tagcgtaagg aatagcagta gaaaaagtct
     3781 gaatcaaaaa tgaagttctc tcaaaagtta gaaataaaac tctgactttg ggagaatttc
     3841 attttattat taatatataa aatttcttga catacaac
//
LOCUS       DBEJKC010000096         3503 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.096, whole genome shotgun sequence.
ACCESSION   DBEJKC010000096 DBEJKC010000000
VERSION     DBEJKC010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3503
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.096"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..102)
                     /locus_tag="ACL3G6_001981"
     CDS             complement(<1..102)
                     /locus_tag="ACL3G6_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
                     /protein_id="HGR0546446.1"
                     /translation="MEYSIDFRKKVLSYCERTGSITEASHVFQISRNT"
     gene            complement(287..898)
                     /gene="rpsD"
                     /locus_tag="ACL3G6_001982"
     CDS             complement(287..898)
                     /gene="rpsD"
                     /locus_tag="ACL3G6_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HGR0546447.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1093..2145)
                     /locus_tag="ACL3G6_001983"
     CDS             complement(1093..2145)
                     /locus_tag="ACL3G6_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGR0546448.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2142..2840)
                     /locus_tag="ACL3G6_001984"
     CDS             complement(2142..2840)
                     /locus_tag="ACL3G6_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0546449.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(3007..>3503)
                     /locus_tag="ACL3G6_001985"
     CDS             complement(3007..>3503)
                     /locus_tag="ACL3G6_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HGR0546450.1"
                     /translation="ALDGNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGKPDLDN
                     IVATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSSTN
                     TMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLKNK
                     KEEN"
BASE COUNT          972 a          779 c          670 g         1082 t
ORIGIN      
        1 ggtattacgt gagatttgga aaacgtgtga tgcttctgtt atactacctg ttcgctcaca
       61 ataagagaga acttttttac gaaaatctat tgaatattcc ataaaagatt ataccacatt
      121 gtgtactatt tttggttcat tttactatat cactttggac tatatcggtc tagttatgtc
      181 taaacgatta tagctggata ctaagagaaa tcaaaaaagc actaagggag aacgtcccaa
      241 agtgcttagt ttcaaggctt tacagcctat cttatttaat aaaatattac aacattttgt
      301 tgtagaattc aacgacaagt gcttcgttga tttctgggtt gatttcgtcg cgttctggca
      361 agcgagtcaa tgaaccttcc aatttttcag cgtcgaatga tacgaatgct ggacgtccaa
      421 gagtagcttc tactgcttca aggattgctg gaactttcaa tgatttttca cgaactgaga
      481 tcacttgacc tggagttacg cggtatgatg ggatatcaac gcgtttcccg tcaacaagga
      541 tgtgaccgtg gtttacaaat tgacgagctt gacgacgagt agtcgcgaga ccaagacggt
      601 aaacaacgtt atccaaacga cgttccaaaa gaagcataaa gttgaaacct aggattccgc
      661 ctttgatttt tgtagcttgt acaaacaagt tacggaattg tttttcacct acaccgtaag
      721 tgaaacgaag tttttgtttt tcagccaatt gcaaaccgta ttctgacaat ttagaacggt
      781 tgtttggtcc gtgttgtcct ggtacgtagt tacgacgtgc caattcttta cctgtacctg
      841 taagtgaaag gccaaggcga cgagcttgtt tccaagatgg tcctgtataa cgtgacatat
      901 gaatgtcctc ctgatataaa taatatttcg gtggaaatag tcacttagaa agccctgatt
      961 cgtgcagatg cccttcgcct aaacagccaa ggttacttat cataagacac ctgttgacga
     1021 gcttcatgct ttcctgctga tatttcacac aaaattcatt ctaccatgaa tagctggatt
     1081 tgtaaagggg ttttaggctt tattttcact accagagagg ttgagaacga gagtaaaggt
     1141 acttcctaga ccgtactggc tgctgactgt gatttcccca cccaattgat gggccaattc
     1201 acgcgcaatc gcaagtccta atccatgacc acctgtcttc atgttacgcg aagtttcgac
     1261 acgataaagg cgtttgaaaa tattttccaa atcctctggg gcaatgccct gcccttcatc
     1321 ggtcacactg attgaaagct ggcccttctc cagcttagcc accacttcca gcttggttcc
     1381 tggagcagaa tatttaaaag cgttatcgac cagattcacc aagatacgag aaagcttagc
     1441 ataatctccc tcaatccggg cagactctgg gattacctgc aagtggacat ctcttctctc
     1501 ctgctcaatc aaaaactgaa attcactcat gcactcaatt aagagcttgt ccagaaaaat
     1561 actgtcttta ctggtagttt ccacctgatt tctagctgtg tttagggtca aaaaattcaa
     1621 ctcctcaacc agtttattga gcctctccgt ctggcgtcca atggttgcta gataatgagc
     1681 ttgctccgac tccttgataa tcccatccaa aatcccttct accgtcgctt ggatcgaagt
     1741 gataggagtc ttaatatcat gcgacaactg agcaatcatc aagccctttt ctcgttcgct
     1801 ttcttccaag gaatcaaagc ttacctgcaa atcatgggac atctcattaa aagtttgccc
     1861 taattgctga aattctacag gaccttgaac ctccaaattt gaaggaaaat ccttggccgc
     1921 tacccgcttg gcatgctcct tgagtttgcc caacgacgta aagactggca ataggagaaa
     1981 gagactaatc ccagcaccga caaggctggc aacgatggtc atcccaagca aaaagtaaat
     2041 ctcgcctttc gcaatcagca ttttttgaac agcccaaaaa acaaccaaaa tggttaagag
     2101 ggttgaaata atatatccaa ccaaaatata actttttagt ttcatgtttg tcctctcggt
     2161 ttctctatct tatatcccaa cccccaaact gtcttaatag tgggcgtttg gtcactacta
     2221 tattttgcca gctcctgtcg aagagcatgg atatgcacat tcaaggtatt ggtgtcatcc
     2281 acgtagtctt ctttccagat cttttcatag aggtctgtct tggagaaaac tcgctctgga
     2341 ttgctagcta aaatccacag caattcaaat gatttaacag ttaaatccag catttcttct
     2401 cctatttgaa cttcatgact actatgattc atttttagat tgccaaggga aatcagctct
     2461 gtttcgcccc cacgatgaag gcggcgcaaa atattgtgga cacgcaaaac tagctcacgt
     2521 gggctaaaag gcttagcaat aaaatcatct gctcccaagc tcaggccgta aatcttgtcc
     2581 tgctcactgg tcttagcagt aataaatagg aaaggctgct ctggtgataa gtattgaacc
     2641 tcactgatta aatcataacc atccatccga ggcatcatga catctgtgat aatcaaatca
     2701 atcggttttt tcttgaacag ctctagcgct tccagtccat catgggctac caagacctga
     2761 taacctgcct gaattaagta tctctgatga atatctgtga tttctacctc gtcgtcaacg
     2821 agtaaaattg tctttcccat ctgtctctcc tttgataaaa acagtgctat actgctttaa
     2881 gtataacact atttttattg ttttacgatg attttaatct gctattgaaa gaaagtcctg
     2941 attgctgatt gagttgttaa actaatctta gtcagcccac tatccatcat ttatttcctt
     3001 agctgattag ttttcttctt ttttgttttt caaacctaga ccaccgagta aacctgcaag
     3061 cgcaagccca aggaaaccaa tacttgccat tgatgtttga gtctcaccag tatttggtag
     3121 catagcttta tcctctgaca tcatcgtatc agacatcttg ttagcagaag cagccatatt
     3181 ttcacctgcc atcgtgttgg tagaacttgt catggtgtca gcaggcatgc tatctgtagt
     3241 acctgtagca tgattgtgat tcatcggagt cacgccagaa ccagagttag aaggtgataa
     3301 tgaaccattt gctgtgtctg atgtttcttt aacatttatc ttaatagtga cttttttagt
     3361 tgctacgatg ttgtccaagt ctggtttacc gtctttgtta ccatagacat tgactgtagc
     3421 actgtaagtt tgagtaccat ttgctcggaa ctggtcaatg agcgcttgtt tttctttgcc
     3481 agctacattt ccgtccaagg cta
//
LOCUS       DBEJKC010000097         3237 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.097, whole genome shotgun sequence.
ACCESSION   DBEJKC010000097 DBEJKC010000000
VERSION     DBEJKC010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3237
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.097"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            629..1975
                     /gene="gdhA"
                     /locus_tag="ACL3G6_001986"
     CDS             629..1975
                     /gene="gdhA"
                     /locus_tag="ACL3G6_001986"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HGR0546451.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVPWVDRDGKVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGHLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(2481..2651)
                     /locus_tag="ACL3G6_001987"
     CDS             complement(2481..2651)
                     /locus_tag="ACL3G6_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546452.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2664..3167)
                     /locus_tag="ACL3G6_001988"
     CDS             complement(2664..3167)
                     /locus_tag="ACL3G6_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0546453.1"
                     /translation="MDKKILSQNLGVVPQDSFLLNRSILDNITLKNEVTSQKIEEVCK
                     AVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDT
                     INEERITKYIKSQGCTQIIVAHRLSTIKDADIIFVMKGGKIVESGNHKYLMELGGEYY
                     SLYTKRK"
BASE COUNT         1018 a          595 c          532 g         1092 t
ORIGIN      
        1 tcatattttt ttacatttcg ctaaatcgtt gtttgattac agtctaaaag ctctataatc
       61 tctttataag atttgcccat cagacgaaat atagtagatt gaaactagaa tagtacacct
      121 ctacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttg ccctgttctt
      181 gtttcgtttt actatagaac gatttgaagg cgtttatgat atttagctgt acgagagtct
      241 tttaaaagtg ttttgatggc ttggatttct tctttagttg atttcatatc actattatat
      301 aatgcttttt gattttagtc tggtataaat attgctttcc tccaaaatgg tcataatttt
      361 actagcaaat ctaacatatc acggataaat taacaagtga tttctgaatt gctaaacatt
      421 ttcttttctt atagcatacc atactttaag attttgtctt tgagaaagat atttccaaga
      481 aaaacgttcg tttttttatc tattttcaaa aaaaaccaaa aactgaattg aaagaatttt
      541 tagaaaattt ctgttttttc tttacagtga aaaaaaattc tgctataatg tcttatgtaa
      601 taaaatatga caataaaagg agaacgatat gacatctgct aaagaatata tccaaagcgt
      661 gtttgaaact gtaaaagctc gtaacgggca cgaggctgaa ttcctccaag ctgttgaaga
      721 atttttcaac actttggaac ctgtatttga aaaacaccct gagtatatcg aagaaaatat
      781 cttggcacgt attactgagc ctgagcgcgt gatttctttc cgtgttcctt gggttgaccg
      841 tgatggaaaa gttcaagtaa accgcggcta ccgtgttcaa ttcaactcag ctgttggacc
      901 atataaaggc ggacttcgtt tccacccaac tgtaaaccaa gggattttga aattcctcgg
      961 atttgaacaa atctttaaaa acgtcttgac tggacttcct atcggtggag gtaaaggtgg
     1021 atcagacttc gatcctaaag gtaaaacaga tgctgaagtg atgcgcttct gccaaagctt
     1081 catgactgaa ttgcaaaaac acatcggacc atcacttgac gtacctgctg gtgatatcgg
     1141 tgttggtgga cgtgaaattg gttaccttta cggtcaatac aaacgtctta accaatttga
     1201 tgctggtgtc ttgactggta aacctcttgg atttggtggt agcttgattc gtccagaagc
     1261 aactggttac ggtttggttt actatactga agaaatgctc aaagctaacg gtaacagctt
     1321 tgctggtaag aaagtcgtta tttcaggttc tggtaacgtt gctcaatatg ctcttcaaaa
     1381 agcaactgaa ctcggtgcaa ctgttatttc tgtttctgac tcaaatggtt atgtcatcga
     1441 tgaaaatggt atcgacttcg atcttttggt tgatgttaaa gaaaaacgtc gtgctcgttt
     1501 gactgagtat gcagctgaaa aagcaactgc aacctaccac gaaggtactg tatggactta
     1561 cgctggaaac tatgacattg ctcttccatg tgccactcaa aacgaaatca acggtgaagc
     1621 agctaaacgt ttggttgctc aaggcgttat ctgtgtatct gaaggtgcca acatgccgag
     1681 cgaccttgat gccatcaaag tttacaaaga aaatggtatc ttctacggac ctgcaaaagc
     1741 tgccaacgct ggtggtgtag ccgtttcagc tcttgaaatg agccaaaaca gtcttcgcct
     1801 ctcatggact cgtgaagaag ttgatggcca tctcaaagac atcatgacaa acatcttcaa
     1861 cacagctaaa acgacttcag aaacatacgg tcttgataaa gactaccttg caggagctaa
     1921 cattgctgcc tttgaaaatg tagcaaatgc catgattgca caaggtattg tttaagattt
     1981 atttactcaa tcctcaatca ctacgattgg ggatttttag cttgaattaa aaaattggaa
     2041 aatctaatta aataaaatga aatgaaataa aaactgaaca aattgattgc ggaattcaaa
     2101 ccaatttcta acatacttct agaaattaat ttgacttttc taatcgattt gttcatatct
     2161 tatttcaatt tactatactt acttaaccct ttttatactc aatgaaaatc aaagagcaaa
     2221 ctaggaagcg agccgcaggc tgtacttgag tacggcaagg caaagctgac gtggtttgaa
     2281 gagattttca aagagtatta aacaaaaaga aaaaccgcta ctcctaagaa tagcgattta
     2341 atcatgtttt taagctacta ctgtagttgc tctattattt aagtgttatg aataacttca
     2401 atatctttaa agctttttgt tagatttata atttcaacta tagccatctc tactccttag
     2461 tttacagcaa aaaattatgc ttaattctta ttgtttttgt aaacaatcag cgaacccaat
     2521 actattccat tcaacaagcc taaagaaata ccatattcaa ctggaaaatc taaaaaaatt
     2581 gcaaacacta ttccaatcat cacccctagt gaggctgttg ttaaaattac atattcattt
     2641 tctttcttca ttttctttac acctcatttc ctttttgtat ataagctgta gtactctcca
     2701 ccaagctcca ttaagtactt atgatttcct gactcaacaa tcttaccacc tttcattaca
     2761 aaaataatat ccgcatcctt aatcgttgac aatctatgag ctacaattat ttgagtacag
     2821 ccctgacttt ttatatactt tgttattctt tcctcattaa tagtgtctaa agcactagtt
     2881 gcttcatcta aaattacaat actaggatta tttattaatg cacgtgccag tgctatccgt
     2941 tgtctttgac cacctgaaat atttgaaccc atctctgaga tgatagtatt aaatttcatc
     3001 ggcatagcca tgatttcatc atagatttga actgctttac aaacttcctc tatcttttgt
     3061 gaagtaactt cgttctttaa agttatatta tcaagaatac ttcggttcaa taaaaatgaa
     3121 tcctgtggaa ctactcctaa attttgactt aatatttttt tatctatttg attaatattt
     3181 ataccatcaa ataaaacttt tcctgtatca atcttatata atcctgatgg tattttt
//
LOCUS       DBEJKC010000098         3112 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.098, whole genome shotgun sequence.
ACCESSION   DBEJKC010000098 DBEJKC010000000
VERSION     DBEJKC010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3112
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.098"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            24..218
                     /locus_tag="ACL3G6_001989"
     CDS             24..218
                     /locus_tag="ACL3G6_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGR0546454.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(340..506)
                     /locus_tag="ACL3G6_001990"
                     /pseudo
     CDS             complement(340..506)
                     /locus_tag="ACL3G6_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558122.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(584..1894)
                     /locus_tag="ACL3G6_001991"
     CDS             complement(584..1894)
                     /locus_tag="ACL3G6_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HGR0546455.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGKTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2131..3003
                     /gene="nadC"
                     /locus_tag="ACL3G6_001992"
     CDS             2131..3003
                     /gene="nadC"
                     /locus_tag="ACL3G6_001992"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HGR0546456.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFKRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALDDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT          964 a          515 c          709 g          924 t
ORIGIN      
        1 atttttcatt acgaataata tagatgaagg ggaaagagta tgaaaacaga actgtttctt
       61 ttgctattag ttcaaaagga gaaaaaatga aagtagaaaa tatttcgtat agggtggatc
      121 atcgtatatt gtttgataat atttcttttg atacttcgag ttcaggcgtg acattaatta
      181 ctggtaaaaa tggtacagga aagtcaactt tactatagta gattgaaact agaatagtac
      241 acatctactt ctaaaatatt gttagaaatc gatttgacta tcctgatcta tttgtcctgt
      301 tcttatttca tttcactaca tctcaaattg agtatgacga agtgcgctcc catgtcctgg
      361 gaacgcactt tcttcatatt tttcatattc ttgaatccat cgataaagac tattgggatg
      421 aatttttaaa gttgaactaa tcatttttac aggatgaggt ttacagcaga gagtttgaag
      481 gctttatcaa aggtttttct tggcataatg acttttcctc gtttccactt aattttgtgt
      541 ctactttatt ataccaagtc cacccttaag ttagataata aatctaactt aaggaagcta
      601 gaaggatgag aatccaggtg gtcaagagtc ccaaacttaa gctgatgggg acacccagaa
      661 taatttgctt tttgaaggca aggccacgtt cctctatatt gggaagtgag agttgaatga
      721 gagaaccagc tgatgaaaag ggtgagatat tagtagatag agcgccaata acggtggctg
      781 ttgtgagtaa gtgaatatca atctggggat tttgagcact gatgatagca atgatgggaa
      841 agagggctgg agctacaacg gatagggtgg aactaaagag tgacatcact ccggctatca
      901 cacaaaagaa cagaggtaac cagaaatgag gaatggatgt tgtcatgagg tgccctatca
      961 gtgtgactaa acctgacttg accgctagag acattagtaa gctcatgccg cagagcatga
     1021 taattgtagc ccagggaacc ttagctaaaa tggcttcttg cttccctaat ttgagcctta
     1081 aggcgaggca gaccatgagt attgagacaa agccaatatc aaatgttttt tgataagtag
     1141 ctatccaggc gatgtttggg aaaatgagat gcaacaaggg aaaaagccaa accaaaacca
     1201 tgctgctgat catgagcaag gtggtttgtc tttgaacctt gctgaggagt ggtggttggt
     1261 caatagtcaa ggatgagttt gtttttccct tactatagtg actgtaacag gataataaaa
     1321 gcaagacgat gagtgggtag ataatgctga cgataaagat atgattgcca agtgaaaaag
     1381 cttgctcttc ccatcccatt tgcttaaaca ggccttgaaa gacaatgcct gagctactgg
     1441 ttatcaaatt agcccctcct gaagctcccc aattgacggc ttgagctcca atcaaagggt
     1501 gtttgtccgc tttttgacag agggtaatcg ctagaggaca gcaaacggcc atagtagtga
     1561 aaaatccagc acctaaagca gacaaaaggg ttgccatcag gtataaaatc atgtagaggg
     1621 cgttagggta ggtgcgtgtg cggtagagaa tgtgttgagc caaaacatca agagtaccgt
     1681 tagttattgc aaagttataa aagagagaga cgctaaaaat ggtaaaaaag agtgaggttg
     1741 gccaaaaatg aagaagttct ttggggctta atcccatgag agtggttgcg atgaggtaag
     1801 aaaaagcaat agccagcagg ccaatattga ttttggtgcg gtaaccaatt ccaatggcta
     1861 gagcaatggc gctaatcatt attaaatgaa tcattgaatt gtcctttcag ttagaatatg
     1921 gaaataggtt ggcaattttg gcgctcaaaa gaccacctgt ttcctattgg tacttgacta
     1981 ttatacacaa aaaaaataca attgtcttga caattgtatt gacacttgtt agaattaaaa
     2041 atgaggtatt caggcttgtg atttcctatg gaagttaata gtgattgcct ctaatgctta
     2101 caagtgatat taaaaataga ggacttagtg atgtcaatca tttcaactga tttaacccct
     2161 tttcaaatag atgatacatt gaaagcagcc ttgcgagaag atgttcattc cgaagattac
     2221 agtaccaatg ccatttttga tcatcatggc caagccaagg tgtcgctttt tgccaaggaa
     2281 gctggtgttt tagcggggct aaccgttttt aaaagggttt ttaccctatt tgatgccgag
     2341 gtgaccttcc agaatcctca tcaatttaag gatggggatc gtttgactag tggcgatttg
     2401 gttttagaaa tcataggctc ggtgagaagt ctcttaacat gtgaacgcgt tgccttgaat
     2461 tttttacaac atttatcagg gattgcttcg atgacagctg cttatgtaga agccttagac
     2521 gatgattgca ttaaggtatt tgatactcga aaaactactc ctaatttacg tctttttgag
     2581 aaatatgccg tgagagttgg cggtggctat aatcatcgct ttaatttatc agatgctatc
     2641 atgctaaaag acaatcacat tgcggcagta ggtagtgttc aaaaggcaat tgctcaagcg
     2701 cgtgcctatg ctccttttgt gaaaatggtc gaggtggaag tggaaagcct tgctgctgcc
     2761 gaagaagctg cggcggcggg tgctgatatt atcatgttgg ataatatgtc attggaacag
     2821 attgaacagg ccattaccct aattgcagga cgttctcgga ttgaatgttc tggaaatatt
     2881 gatatgacca ctattagccg ttttcgtggt ttagcgattg attacgtctc cagtggtagt
     2941 ttaacccata gtgctaagag tcttgatttt tccatgaagg ggttaaccta ccttgatgtc
     3001 taagttgtaa aataaactaa ctttttaaag gatgtctttc ctctagaacg agttttatgt
     3061 cagatagttt aaacgcctct tcaaatatag taaaatgaac caaaaatagt ac
//
LOCUS       DBEJKC010000099         3032 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.099, whole genome shotgun sequence.
ACCESSION   DBEJKC010000099 DBEJKC010000000
VERSION     DBEJKC010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3032
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.099"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..437
                     /locus_tag="ACL3G6_001993"
                     /pseudo
     CDS             1..437
                     /locus_tag="ACL3G6_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826497.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            417..542
                     /locus_tag="ACL3G6_001994"
                     /pseudo
     CDS             417..542
                     /locus_tag="ACL3G6_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812181.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(514..1989)
                     /locus_tag="ACL3G6_001995"
     CDS             complement(514..1989)
                     /locus_tag="ACL3G6_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGR0546457.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVVELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            2696..>3032
                     /locus_tag="ACL3G6_001996"
     CDS             2696..>3032
                     /locus_tag="ACL3G6_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0546458.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNCKRSVKKSSVTKELKEKILHYHNQ
                     KFSPDKKQAS"
BASE COUNT          948 a          668 c          546 g          870 t
ORIGIN      
        1 aagatactgg acattatgcc tttaatctac tgaacttcct gcatgaacaa ggatataaag
       61 tttacaccta cactcctttg ctcatcaagg aatttgccaa atcattatca cttcgcaaga
      121 ctaaaacgga taagaaagac gctcatggca tcgctcttaa acttctttct gaccccaatc
      181 gtgaacaatt tcaacacgat aatcggcaag tagaactaaa aatactggct agacatattc
      241 atcgtctcaa gaaaaaacag tctgattgga aagtacaata cactcgttgt cttgatatca
      301 tctttcctga gttggataaa atcgttggaa agcattcaga atatacctac caactcttga
      361 cacgctaccc taatcctcag aaaaggcttg aggcaggatt tgataagctg atagaaatta
      421 agcgattgac cgcttctaat tcaagggctt tttgccgtgc tctaaaatca tcgccaaatc
      481 atcaaattga aataagaaat agtttagata aaactattga cttttcttat agtttgtctt
      541 tctcttaata acgttgatat gattgacctc tggatcttcc gtcccttgga gggagcaacc
      601 acgttccttg gcgaattgga tatagtctac aatttctcgt gtaatgcgtt caccaggagc
      661 caagatagga atccctggag gatagcacat gacaaattct ccacagacct gtccaacaga
      721 ctcatctaag gtcaaacttt ttctctctga atagaaagct tcttgtggag acagcaccaa
      781 ctcgggctga atatattctc cagctattaa gtccttccca tctcgtgaat agagtctctt
      841 aatatcagcc agagcaccaa ccaagcgctc gatgtcttgg atgcggtcgc cgatggaaat
      901 ataagccaag atattgccga tatcaccaaa ctcgatctga atgtcgtatt cgtctcgcaa
      961 gaggtcataa acctcgatac ctgttaagcc tattccctga gtgtaaactg acaacttggt
     1021 tacatcaaaa tcacagaccg acacaccatc tattaactct tttgagtaag catagtaacc
     1081 gccaatggca ttgatttcat gacgagcgta ctcggatagc tcaacgactt cctcaaacga
     1141 ctctttacca cgaagggcca agttgcgacg tgaaatatcc aaactagcca tcaataagta
     1201 agaggcagat gtagactggg tcaggtttat aatctgacga acgtactcgg gattcatctg
     1261 ctccccgatt aaaagaagcg aactttgtgt caaactccca ccagacttat gcatggaaac
     1321 tgctgccata tcagctcctg catccatagc agaaattgga agtttaccag tgaaatgcaa
     1381 atgcgctcca tgggcttcat ctactaaaac catcatgcca gcttcatgag ccatttctgt
     1441 caaccccttt aggtctgaac agatgccgta gtaagtagga ttgttgatta ggatagcctt
     1501 agcatctgga tgatccttta tggcctgtgc tactcggtca ttttcaagac ctaaagcgat
     1561 accaatctta ggatctacac tcatctcgat atagatggga atggcaccac atagaaccaa
     1621 cgcattgata gcagatttat ggacatttcg tggcagaata atcttatctc ctgccttgca
     1681 ggttgccaga atcatagtct gcaccgatga agttgttcca ccaatcatta gaaaggcatg
     1741 gctagctcca aaagcatctg cagccagctc ctctgcatca cgaataatcg aaataggatg
     1801 gcctaaatta tccaagggtt tcatcgaatt gacatcaatg cctacacatt tttctcctaa
     1861 gagttcgaca agttctggat ttccccgtcc acgcttgtga cctggaacat caaagggaac
     1921 aatccttttc ttgcgtaact tcaccaaggc ctcataaatt ggggcttggt tttgatctaa
     1981 ctctttcaaa acatactcct ttcaatattt ttaggacctt atgaaaacta aggaactaaa
     2041 ggttgactca tgaaaaaaga gcaggttttc acctgctctg caatcttctg acgtgtttat
     2101 tttggtttct gttgagtatg tctgttcccg atgtttccta actctctagt agcaaatatt
     2161 acgtacttta ttgatcgttt cacaagatga cgtgtgcttt caccacacta aaaatttatg
     2221 aattaggaca agtgtcctaa catcaactta taaaagtagg cttttaaccc tatcaataat
     2281 gtggcttttc aaccacgctt cggcattcaa ccctgcctgt ccgtaggcat tttttactcg
     2341 ggtttatatt tgctagaaaa catcatctca ttttctaagc tttattacta tatcatgttt
     2401 ttaagaactt gtaaagtatt ttttgataaa aaacaaaaat ataatagatt gaaactagaa
     2461 tagtacacct ctgcttctaa aacattgtta gaaatagatt ttactgtcct gatcgatttg
     2521 ttctgttctt gtttcatttt actatatgtt cgtaaatgaa agttctataa tgaagttagc
     2581 cacccagtcc tcctaaaaat tagatggttc aactagctga tagctcttgt aggcataaga
     2641 aaacacctct gtgttatact tgttgttcaa ccacaaacac aagaaaggca cagagatgca
     2701 agacaattat actacaaaag ccaaacattt gacaatcgat agccgtcgct taatcgaaag
     2761 atggaaaaaa gaagggaaat caaatagaga aattgcctct ctgcttggaa aagttcctca
     2821 aactatccac actgaaatca agcgtgggac agtccgacaa tgtcttggaa aagggcgctt
     2881 caaagaggtt tattctgccg actatgctca acagtcttat gaaaacaatt gcaagcgctc
     2941 ggtcaagaaa tcaagcgtga ccaaggaact aaaggaaaag attctccact atcataacca
     3001 aaaattttcg cctgataaga aacaggctag ca
//
LOCUS       DBEJKC010000100         2992 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.100, whole genome shotgun sequence.
ACCESSION   DBEJKC010000100 DBEJKC010000000
VERSION     DBEJKC010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2992
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.100"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            64..780
                     /gene="ldcB"
                     /locus_tag="ACL3G6_001997"
     CDS             64..780
                     /gene="ldcB"
                     /locus_tag="ACL3G6_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase LdcB/DacB"
                     /protein_id="HGR0546459.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKAKNEDGAAKTEQTAKADGTVG
                     SKAQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELLKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            1089..1514
                     /gene="rplK"
                     /locus_tag="ACL3G6_001998"
     CDS             1089..1514
                     /gene="rplK"
                     /locus_tag="ACL3G6_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HGR0546460.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            1722..2411
                     /gene="rplA"
                     /locus_tag="ACL3G6_001999"
     CDS             1722..2411
                     /gene="rplA"
                     /locus_tag="ACL3G6_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HGR0546461.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
BASE COUNT          999 a          561 c          675 g          757 t
ORIGIN      
        1 taaaagatta gtcaaacgtt tatcgttaga agtagataaa ctattagaaa taaaggagta
       61 gaaatgaaaa aaagatacct agtcttgaca gctttgctag ccttgagtct agcagcttgt
      121 tcacaagaaa aagcaaaaaa tgaagatgga gcagctaaaa cagaacaaac agctaaagct
      181 gatggaacag taggaagtaa ggctcaagga gctgcccaga aaaaagcaga agtggttaac
      241 aaaggagact actacagcat ccaagggaaa tacgatgaaa tcatcgtagc caataaacac
      301 tatccattgt ctaaagacta caatccaggt gaaaatccga cagccaaggc agaattgctc
      361 aaactcatca aagcaatgca agaggcaggt ttcccgatta gcgatcatta cagtggtttt
      421 agaagttatg aaactcagac caagctctat caagattatg ttaaccaaga tgggaaggca
      481 gcagctgacc gttactctgc ccgacctggc tatagtgagc accagacagg cttggccttt
      541 gatgtgattg ggactgatgg tgatttggtg acagaagaaa aagcagccca atggctcttg
      601 gatcatgcag ctgattatgg ctttgttgtc cgttatctca aaggcaagga aaaggaaaca
      661 ggctatatgg ctgaggaatg gcacctgcgt tatgtaggaa aagaagctaa agaaattgct
      721 gcaagtggtc tcagtttgga agaatactat ggctttgaag gcggagacta cgtcgattaa
      781 tactcttcga aaatctcttc aaaccacgtc agcgtcgcct tacctactga ctgcgtcggt
      841 tctattcaca acctcaaaac agtgttttga gctgacttcg tcagttttat ctgcaatctc
      901 aaagctgtac tttgagcagc ctgcggctag cttcctagtt tgctctttga ttttcattga
      961 gtataaaaaa taaacttttc tcttgcaatt ccagataaat agtgtataat ggatgggtat
     1021 gtgaaaaaca tacttgtggg aggtaaaaat ctctaattac cgccaaaacc acaaaggagg
     1081 atttaaaaat ggctaaaaaa gtcgaaaaac ttgtaaaatt gcaaatccct gctggtaaag
     1141 ctacaccagc tccaccggtt ggacctgctc ttggtcaagc tggtatcaac atcatgggat
     1201 tcacaaaaga gttcaacgct cgtacagctg accaagctgg tatgatcatt ccagttgtta
     1261 tctcagttta cgaagacaaa tcatttactt tcgttacaaa aacaccacca gctgctgttc
     1321 ttttgaaaaa agctgcaggt gttgaaaaag gatcaggtac acctaataaa actaaagttg
     1381 ctacagttac tcgtgcacaa gtacaagaaa ttgcagaaac taagatgcca gatttgaacg
     1441 cagcaaacgt agagtctgca atgcgtatga tcgaaggtac tgctcgttct atgggattca
     1501 ctgttgttga ctaatcaata acacagtaga aaatctcaca gcagtctatt agttgctttt
     1561 catactaggc aagtgactga gccttgtact tgggtacagc aagggagctt aaggccgtag
     1621 gaagagaaaa atagtagact gaaaacccgc aagacttcat catttcgaga agtgacgtgg
     1681 gagatgaaaa tcgattgaac cacttacaag gagaatagaa aatggctaaa aaaagcaaac
     1741 aacttcgtgc tgctcttgag aaaatcgaca gcacaaaagc atacagtgta gaagaagctg
     1801 tagcacttgc aaaagaaact aactttgcaa aatttgacgc aactgtagaa gttgcttaca
     1861 acttgaacat cgacgttaaa aaagctgacc aacaaatccg tggagcaatg gtattgccaa
     1921 acggtactgg taaaacttca cgtgttcttg ttttcgcacg tggtgcaaaa gctgaagaag
     1981 caaaagctgc tggtgcagac tttgttggtg aagatgacct tgttgctaaa atcaacgacg
     2041 gttggttgga cttcgacgta gttatcgcta cacctgatat gatggctctt gttggacgtc
     2101 ttggacgtgt ccttggacca cgtaacttga tgccaaaccc taaaactggt actgtaacaa
     2161 tggatgttgc taaagcagtt gaagagtcta aaggtggtaa aatcacttac cgtgctgacc
     2221 gtgcaggtaa cgttcaagca atcatcggta aagtatcatt tgaagctgaa aaattggttg
     2281 aaaactttaa agctttcaac gaaacaatcc aaaaagcaaa accagctaca gctaaaggaa
     2341 cttacgtaac aaacttgact atcacaacta ctcaaggtgt tggtatcaaa gttgacgtaa
     2401 actcacttta atcagtagtt aaagtaatgt aaaaaagttg aagacactat gtctcaactt
     2461 tttttgatgt acgacgggca tgtcgtatat ctgaggtgta agtcctcggt gggcacctac
     2521 taccggtgaa cccaatagcg attcccaagt ctgactatcg tgaggtagcg gattaaaacg
     2581 gtctggggat agaccgtttt aagtctgacg ctggaaataa gaatcgtcag aggaagggat
     2641 agcgaaatcg tggctctacg aacaggaacg tgataataag gcgtatatag cggataaggt
     2701 atctggctgg ggcgaccact atcaattata ataaaatgaa ataagaatag gacgaatcgt
     2761 tcaggacagt caaatcgatt tctaacaatg ttttagaagt agaggtgtac tattctagtt
     2821 tcaatctact atagtagctc agaagtcggt acttaaacgt gctatatcaa aaccagtcct
     2881 tgaaaaacgt ggactggttt cgtgtttgga ttattacctt gaacgacatg cgttaaaagt
     2941 tagttgaacc gccgtatgcc gaacggcacg tacggtggtg tgagaggggc ta
//
LOCUS       DBEJKC010000101         2952 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.101, whole genome shotgun sequence.
ACCESSION   DBEJKC010000101 DBEJKC010000000
VERSION     DBEJKC010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2952
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.101"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(85..1026)
                     /locus_tag="ACL3G6_002000"
     CDS             complement(85..1026)
                     /locus_tag="ACL3G6_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGR0546462.1"
                     /translation="MKQAKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINALFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(1004..2767)
                     /gene="aspS"
                     /locus_tag="ACL3G6_002001"
     CDS             complement(1004..2767)
                     /gene="aspS"
                     /locus_tag="ACL3G6_002001"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HGR0546463.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETSKTN"
BASE COUNT          859 a          697 c          591 g          805 t
ORIGIN      
        1 agatagaact gacgaagtca gtaacataca tacggtaagg cgacgctgac gtggtttgaa
       61 gagattttcg aagagtatta atcactaatt atctatctca acaaatcttc ctagaatatg
      121 aacattttcc gagacagaga caaaggagct tggatccact tgtgtcataa tctgtttaaa
      181 ttcattaaac tctgcacgtg taatgacagt gattaaaact gcctttctct cgtgattata
      241 ggttccttct gcatcatgga tcatggttgc tccgcggtgc aattttttat ggattttttc
      301 aattaccttc tctggatgat ttgtcacaat catggcctgc atacgctttt gcttagtaaa
      361 gactgcgtct gtcacacggc tagagacaaa gatggtaatc atagaataaa gagcgtattt
      421 ccaaccaaag gtcaaacctg ctatcagcat gatagttcca tttaccaaga aagaaatact
      481 accaacattc ttacccgttt tcttgcgaat agtcaggctg acgatatccg tcccaccact
      541 ggagatattg tttcgaagag caaaaccaat ccccaaaccc ataacaacac ccccaaaaag
      601 ggcattgata atgggatcct ccgtcaaggt tgccacaggg acaaactgga taaagaagga
      661 actcatagat accgtgataa aggtaaagac ggtgaactta tggccaatct gataccaagc
      721 taagaccatc aaagggaagt taatggcgta gaagcttagc gaaatcggaa tatgaaaacc
      781 aaaccagtga ttactcaagg cagagataat ctgtgccaga cctgttgcac cactcgaata
      841 cacatgccct ggttggaaaa agaaattaac tgctactgct gataaaaaac catagaccag
      901 agaggccgaa atcttctcat catacttttc tcgagagata ctttgtaaga cacgtaaaat
      961 ttttatctga taagcaaagc ggcgcagata atagcgccac cgcttaattc gttttgcttg
     1021 tttcatcttc ttctacttgt aagctgagtt cctctagttg tttgagagcg actgttgatg
     1081 gagcttgtgt cattgggtca gttgccttgt tgttcttagg aaaggcaatg acttcacgga
     1141 tattttcttc tccagcaagc aacatgacaa aacggtcaag cccgatagcc aaaccaccgt
     1201 gtggtgggaa accatagtcc atggcttcaa gaaggaaacc aaactggtca ttggcttctt
     1261 cagctgagaa accaagagcc ttgaacatgc gttcttgaag gtctttttgg ttgatacgaa
     1321 ggctaccacc accaagctca taaccgttca agacgatatc gtaagcaatg gcacgaacct
     1381 tagccaaatc accttctaat tcgtgagcag tctcttcctg tggaagtgtg aatggatggt
     1441 gggcgctcat gtagcggcct tcttcttcag accattcaaa catcggccag tcaaccaccc
     1501 aaaggaagtt gaacttatca ttatcaatca agccaagctc tttagcaata cgtccacgaa
     1561 gggcacccag tgttgcatta gccacttcaa gcgtatccgc cacaaagaga accaagtcct
     1621 tatcttcaag agcaagcgct gttgtcaatt cttcttggat accagtcaag aacttggcaa
     1681 ctggtccgtt taattctcca tcaaccacct tgacccaagc aagacctttg gcaccatact
     1741 gtttggctac ttccgtcatc ttgtcgatgt ctttacgtga atagttgtcc gcagctcctt
     1801 tgaccacaat cgcttttaca gcaggtgctt ctgaaaagac tttaaagtct acacctttga
     1861 ccacttctgt caagtcctga agcaacatgt caaaacgagt atctggcttg tcagaaccgt
     1921 aaagagccat agcatcatcg tatttcatac gagggaacgg tagcgttact tcgatgcctt
     1981 ttgtttcctt catcacgcgc gcgatcaagc cttctgtaat atcttggatt tctttctcag
     2041 taaggaagga cgtttccaag tcgacctgag taaattcagg ctggcggtct ccacgcaagt
     2101 cctcgtcacg gaaacattta acgatttggt agtaacggtc aaaaccagca ttcatcaaga
     2161 gctgtttcgt gatttgtgga ctttgaggaa gagcgtaaaa atgcccctta ttaacacgag
     2221 acggcactaa ataatcacgc gccccttcag gcgttgactt agaaaggaat ggtgtctcca
     2281 cgtcgataaa ctccaactca tccaaatagt tgcggataga gtgggtcacc ttggcacgaa
     2341 gtttaagatt ttccaacatt tctggacgac gaaggtcaag gtaacggtaa cgcaaacgtg
     2401 tatcgtcatt tgcctcaatg ccatccttaa tctcaaatgg tgttgtctta gctgtgttaa
     2461 gcacaataag agctgtcacg tttaactcaa ccgcaccagt tggcaactta tcattggctt
     2521 gctcacgcgc agcgacctga ccagtcacct caataacaaa ttcgctacga aggctttcag
     2581 ctgttgccat aacctctgca gatacttttt cagggttgat aaccaactgc atgattcctt
     2641 cacggtcacg aagatcgata aagatcaaac caccaaggtc acgacgacgg ccaacccatc
     2701 ctttcaaggt tatttcttgt ccgatgtgtt cctcacgaac acgaccagca tacatactac
     2761 gtttcattat ttctctcctc ttttattctg ttactatttt accataaaag cgcaggctct
     2821 tcatgaaaat catcagaaaa gtttgccagt ctttaaaagt caggtgaaag ccctaaaaat
     2881 tagcgctaat actcttcgaa aatctcttca aaccacgtca gcgtcgcctt accgtaggta
     2941 tggttactga ct
//
LOCUS       DBEJKC010000102         2779 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.102, whole genome shotgun sequence.
ACCESSION   DBEJKC010000102 DBEJKC010000000
VERSION     DBEJKC010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2779
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.102"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(90..1331)
                     /gene="pbp3"
                     /locus_tag="ACL3G6_002002"
     CDS             complement(90..1331)
                     /gene="pbp3"
                     /locus_tag="ACL3G6_002002"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase PBP3"
                     /protein_id="HGR0546464.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            1434..2543
                     /gene="cozE"
                     /locus_tag="ACL3G6_002003"
     CDS             1434..2543
                     /gene="cozE"
                     /locus_tag="ACL3G6_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell elongation protein CozE"
                     /protein_id="HGR0546465.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
BASE COUNT          820 a          468 c          527 g          964 t
ORIGIN      
        1 tctttgattt tgagtattag atttactcaa aatcaaggat tttgaagatg aacttgtatc
       61 aaaaaatcgc ggtttaaaat cgcgattttt tataatttct cgttaacaaa gcggacaaac
      121 tgattccacc aaacttttaa gaagaaggct ttttcaattt tcttgtctgc taccatttcg
      181 aaactagggc gctctgtggt gatgtaacct tgaccaatca agtccttgtc ttcataagtc
      241 aaatggccaa ccactgttcc agcttcaagt ggtgctggga ttgctttgga atcaggtgtg
      301 aattgaacag attgggaaga ttgattccca acacgttcga ttagatagat atcctctgga
      361 gccactgcag ttactgtatc ttcttttcca tcttgtacag gggctttgct atcttgatag
      421 gcatcgcctt gttgaacgat tttgcgaagt gtaaatgtag aagaaatata atccattagg
      481 gaagatgtag ctgtaaatcg agcgtaagga ttattgtctt gatgatctgc atttaaaaca
      541 actgtgatga ctctcatgcc tttttcgaca gtagtaccaa caaaagactc tccagcctta
      601 tctgttgttc ctgtttttag cccatcaaaa ccaccacggt aagcaggcat accttctaac
      661 atgtagttgg ttgaagtgat tgtcatccca gcaaaagtag aagatggttt tttggtgatt
      721 tctaagactt gtgggtattt tttgatgagg ttgcgagcaa cgatagcgac atcataagca
      781 ctaagcttat tttcctcatc ttttttagaa cctgggtaaa tgttatcccc tagagtttca
      841 ttgttaagac ctgtcgtatt gacaacagtg gcatcctgaa ttccccattc caagagtttt
      901 gcccgcatca tatcgacgaa atctttttct gagccagcaa ttttctcagc tagggcaata
      961 gcggcgctgt tggcactaga taccagagtt gcttcaagca actcttcgac agtataatta
     1021 cgggcctcca taggaatatt actggcttca gaatttgtcg tcaattgata aggataatca
     1081 gaaatatcta caggagtgga gagggtaata cttccgtttt ccaaagcttc atagaccaga
     1141 taaacagtaa tcaattttgt tatggaagca atttcgacag gttgcgttgc atccttctca
     1201 tagagaattt taccagtatt tgcctcaaca gcaatcgcat gtttagcggc aatggtaaaa
     1261 tcttgagcaa cagcagtaga agcaccccct aaaagagaga cagttaacaa agttaaaaat
     1321 atttttttca tagtagtctt attctatcat aaagaaaaaa aatattcttg ctttaataat
     1381 tcatctgtta agctttttga aaatatggta aaataaagtg agggaggtaa ctcatgtttc
     1441 gtagaaataa attatttttt tggaccacag aaattttact cttaaccatc atcttttacc
     1501 tatggagaca gatggggtct ttgattaacc cttttgttag cgtgcttaat acaattatga
     1561 ttccattttt attagggggc tttctttatt atttgacaaa ccctattgtt actttcttaa
     1621 ataaagtctg taaactcaat cgtttgcttg gtattttaat taccttgtgt actttggtct
     1681 ggggaatggt cataggtgtt gtctatctct tacctatttt gattaatcag ttatctagtt
     1741 tgattatatc tagtcaaact atttatagtc gagtacaaga cttaatcata gacttatcta
     1801 attatcctgc gctccagaat ttggatgtag aagctacaat tcagcagtta aacttatcct
     1861 atgttgatat tcttcaaaat atcctaaata gcgtatcaaa tagtgtgggg agcgtcttgt
     1921 cagctcttat cagtactgtt ttgattttga ttatgactcc agtttttttg gtttatttct
     1981 tattagatgg acataaattc ttgcccatgc ttgaaagaac gattctaaag agggatcgct
     2041 tgcatattgc aggcttatta aagaatttaa atgcgacgat tgctcgctat attagtggag
     2101 tttcgattga cgcaatcatt ataggttgtt tggcttatat tggctatagt attattggtt
     2161 taaaatatgc tttagttttt gccatttttt ctggtgtagc caatttaatt ccttatgtgg
     2221 ggccaagtat tggtttgatt cctatgatca tcgcaaatat attcactgat ccccatagac
     2281 tgctgattgc agtgatttat atgcttgttg ttcagcaggt agatggcaat atcttatatc
     2341 ctcgaattgt aggaagtgtt atgaaggttc atccaatcac gattttagtt ttacttttgt
     2401 tgtcaagcaa tatctatggt gtagttggaa tgattgtcgc agtgccaacc tattctatct
     2461 tgaaagaaat ttctaagttc ttatcccgtt tgtatgaaaa tcataaaata atgaaagaac
     2521 gagaaagaga attagctaag taaaagtcag gagaaccctg atttttcttt actggaagtg
     2581 gcctttagat tagaagactg aaaataagtt aaagtcttaa actaattttc acagctaaga
     2641 atagtagaag ttaatctgat aaaaatcgaa aaaaccagtg gaattccgtg tcagggtaag
     2701 ttccactggt tttcatagtc tattaaagtt cgaatgaaac ctatttatag tatattgaaa
     2761 ctagaatagt acacctcta
//
LOCUS       DBEJKC010000103         2711 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.103, whole genome shotgun sequence.
ACCESSION   DBEJKC010000103 DBEJKC010000000
VERSION     DBEJKC010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2711
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.103"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(269..406)
                     /locus_tag="ACL3G6_002004"
     CDS             complement(269..406)
                     /locus_tag="ACL3G6_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HGR0546466.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            complement(608..1195)
                     /locus_tag="ACL3G6_002005"
     CDS             complement(608..1195)
                     /locus_tag="ACL3G6_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0546467.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWSLLVYSLLLF"
     gene            complement(1198..1431)
                     /locus_tag="ACL3G6_002006"
                     /pseudo
     CDS             complement(1198..1431)
                     /locus_tag="ACL3G6_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(1444..1824)
                     /locus_tag="ACL3G6_002007"
     CDS             complement(1444..1824)
                     /locus_tag="ACL3G6_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGR0546468.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            complement(1817..2157)
                     /locus_tag="ACL3G6_002008"
                     /pseudo
     CDS             complement(1817..2157)
                     /locus_tag="ACL3G6_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134542.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2171..2419)
                     /locus_tag="ACL3G6_002009"
                     /pseudo
     CDS             complement(2171..2419)
                     /locus_tag="ACL3G6_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(2419..2589)
                     /locus_tag="ACL3G6_002010"
     CDS             complement(2419..2589)
                     /locus_tag="ACL3G6_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546469.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
BASE COUNT          901 a          559 c          391 g          860 t
ORIGIN      
        1 ttctgtctaa ctattggggt gcagttcaat aaatcttgac ccgttaaatt tgtactgaat
       61 aaactaaatg aaacttttat cccactcact aatactatta tatcaaccca ctacagttga
      121 caaagagaca aaccagccta atggctaact tgtcttcaat caagagagga ttctgttccc
      181 cccatataag cactaacatt ccaacgtgca catattggaa cgacatccat aacttcagag
      241 aatccctaaa gtttacaatt taaatgaatt aacaattttc ccaactaaaa gcactccagt
      301 taccgcaacg gtttgtactg aatgtactaa atcgcattcc atcaacttca tctgtttcgt
      361 caacttgaac agatactaat tgaagattta atacttcttc tgccatagct aactcctcct
      421 atttaaattt ttgggattaa gtgctttatc caccttcatt atactctctc cagcagtaaa
      481 atgcaagcaa tgatacaatg ttgtcacgta gaaaataatg tttccgtaac ttttcaaagt
      541 aacttccatc tctctcccaa aactggaagt tagttttaga agttacctaa aaatcaggtt
      601 acctatttta aaaaagcagc aaactataaa ctagtaggct ccacaccaaa tgtagcccca
      661 tactgcccca taagtccaat ttgtagcgta caagccctaa aaacatcccc agcgatacat
      721 acaaacacca agctataatg gttcctggat gatgtgctaa ggcaaataaa acacttgtca
      781 aagcaactct gatatctaat tttctgacca aattccataa aatttctcga tacagaaatt
      841 cttcaaccat actcgcattg attaagaaca ataaaaatga aaaccaagga atttgatgtt
      901 gaaggccaat taagtttgct tgattcgtgc ttccttgagc atgaatcaga ctaaaacata
      961 gacttataat cagtaggcta acaaattcaa caccaagcca tttcatccta gatttcatat
     1021 tgaccttatg cgcttgtttg cgttggccat acatccataa aaaagaaatg agtgacgaac
     1081 catagagaat ctgtagtata gttaactcac cgatacaaag aaatttcaat aagtatagag
     1141 ataccaatag gacatttact tgttggaata tataaactgg aattattctt ttcatagtta
     1201 cctccgaaat aaatcttcat aatctaaatc taatacctgc acaatccttt ctacccatgg
     1261 actttgaggc attcattgtt ccatcttcta gtggcgaatc ttttgataca aacgattcaa
     1321 ttcacttgga tagtgaaact ctcccgcaaa catttttctg gttaactcaa tccagctgat
     1381 atttctttca gccaaaataa tggacaagtt ctcccaaaat cgttcagcca tattgcttct
     1441 cctttagtta gataaataat gtgtttgcgc catgtaaatc aattgtttcg tatctcttgg
     1501 caatagagct ctagcctctt ccaaattcag acttggataa actcgcttat ttgaaaccgc
     1561 aagaggaagt ctgatggtta gttcaggatt ttttaaaatt atctcaacga aatccgttaa
     1621 tcttagattg tcacggttct taaatcgtaa taaattggga gataaaaact caaaacaatc
     1681 tgaagaatag ctcatcatct caattaattt gtcctttgtc atttcagaaa ctgaatgaca
     1741 agatacctct atgccatagt tttggaagaa atctaaaaga agttgatttc tttgtctatt
     1801 tttacttaga tagagatcaa tcatgggaga cctcccaaag attcggttcc atttgatatt
     1861 ctgacacgat taaggaatct aataaattaa ggaatctaat aaatttgcga agttaatcgg
     1921 tttcttgtct tcatcataag cttttacagt tacttgggtt gtaagtattc cctcttttcc
     1981 ctcggctcga tagccttgtc catataaaac aaaaacgaga ttttgatgat catctacaaa
     2041 ggcatcaacc ccattcttta tgtcttgact ttcaaggaat tccataacgt tttgaagata
     2101 ggattcgtaa aatagtgggt agttatgttt tttatggtaa tcatctaaaa atatcacttc
     2161 aaactcacat ggagagtaat tttgactttg aacagcctaa aagtgccatc aaatttgaat
     2221 tggaataaat caaataaata gccccatcct catcaatcca acctttgctc aaagacaact
     2281 ccaaccgatc ttttaaaact gagtaaacca ccttaacctc cagtttcata ttcttatacc
     2341 gttcactctc aaataaaagt ttggggagct tataataacg ctctgatgtc tgatattgat
     2401 tagcggtaat acgcttcatt attgtccctc caagactaaa attccaacat ttccaaattc
     2461 atcaaatcgg attaaaccta cttgttccat ttcatcaact aactgagttg cttttacaat
     2521 atcaactccc atgatagtca tgagatgact cttcacgaat tgacgtgatg actgtccttc
     2581 cttttgcata attacctccg aaacacaaaa aaaggggtag acaatctagt gtctaccccc
     2641 gaaagtttag gctctataat atttgtagtg ggtaaatccc ttatagatat tatggagcct
     2701 atttttgtgt a
//
LOCUS       DBEJKC010000104         2522 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.104, whole genome shotgun sequence.
ACCESSION   DBEJKC010000104 DBEJKC010000000
VERSION     DBEJKC010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2522
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.104"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..984
                     /locus_tag="ACL3G6_002011"
     CDS             <1..984
                     /locus_tag="ACL3G6_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HGR0546470.1"
                     /translation="NATIASASGADVYEKNSSYGCLMRVGGVDISKTIEHIEKTKQWN
                     YIEGYNQWLEEVLANRKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEK
                     FRFIYTLEVSLFRNELKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINV
                     AKAFGFNPKYMEDESHANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRH
                     IDNSSMMDEILDFPMYTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRS
                     QISCMLMGISSAAAAKTIIEDKSNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            1006..1461
                     /locus_tag="ACL3G6_002012"
     CDS             1006..1461
                     /locus_tag="ACL3G6_002012"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGR0546471.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            1548..1954
                     /gene="cdd"
                     /locus_tag="ACL3G6_002013"
                     /pseudo
     CDS             1548..1954
                     /gene="cdd"
                     /locus_tag="ACL3G6_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221146.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008655 - pyrimidine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
     gene            1967..2416
                     /locus_tag="ACL3G6_002014"
     CDS             1967..2416
                     /locus_tag="ACL3G6_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGR0546472.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDIPKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEEIILYNFLSQMELSEYKVDDDWQ
                     QMNGTALFSIKLKKDMLLLLEPNDAHKTGLLVEEPLNIKKVVFKVKI"
BASE COUNT          931 a          288 c          447 g          856 t
ORIGIN      
        1 aatgcaacaa ttgcttctgc tagtggagct gatgtttatg aaaaaaattc ttcttacggt
       61 tgtttaatga gagttggagg agttgatatc tcaaagacta tagaacatat tgaaaaaaca
      121 aagcagtgga actatataga aggatataat cagtggttag aagaagtatt agcaaatcga
      181 aagtacagag ccactggagc agttttaaaa gatccagttt cttatgatca tgcccctatg
      241 ctttcaaaag acgaccattt tatgaatgat gaaaaatgga attacattaa agaaagatgg
      301 gaaaaattta gatttattta cactttagaa gtatcactat ttaggaatga attaaaaaaa
      361 gctgtagaat ctggggattt taattttgaa atttatcatg atgataaatc tggagtcact
      421 atgaatggcg acggtataag ctatggttca tggggtcaaa atgtagcatt aattaatgtt
      481 gcaaaagcat ttggattcaa tcccaaatat atggaagatg aatcacatgc taatattctt
      541 tctagaaaat ataatttaac atttttatct tttcttaaaa aatatgtacc aggttttgaa
      601 aattctttta tccttgatca gggaactaga gctactaaca gatcatgtag gcacattgat
      661 aattcatcta tgatggacga aattcttgat tttccaatgt atacatttaa gactatgtat
      721 agctatcaaa ctcctaaaga aataacgtac aaatcaattg taggtggaaa attgaataat
      781 ttgtttgtaa taggtaaagg tgcttaccaa tccgaaagtt ttagatcaca aattagttgt
      841 atgttaatgg ggatatcatc agcagcagcg gcaaaaacta ttattgaaga taaaagcaat
      901 actctaaaca ttaatagaga tttgtttaaa tcgaacttag atatattatt tacatgggag
      961 ttttctaatt ggattactga ttaacaaata ataagggaat attaaatgaa tgatactaat
     1021 aaaaatcaat actttgttta tgaatttgat actagctttg tagaaatgtc ttattctcag
     1081 ttttttgaag gatattgtat tcttttttca aaagaaccct atccttcttt atctgatatg
     1141 ccaatggaat ttagaaaaga atttttaatg gaaatgagta tattaggtga tgcgatgctt
     1201 gaagtgttaa atgcctatag aattaattat gatatcttag gaaattcaac acctgtactt
     1261 catgctcatt tatttccgag atacatgtgg gaagaggaag agagaagaaa aactgtagtt
     1321 catagatatg attcttcagt ttttagcaat cctgagtttg aatttactat agaaaagcat
     1381 ggaccaatta ttaaaaaact gaggtctgct attgatagac attatagaga gtatcaacaa
     1441 ttattagatg attcaaactg aactccacat tttcgattag atttaatacc ttgtatatta
     1501 caactaggtt gtggatgata taattttttg aaaaatatat tttaggaatg acttataaag
     1561 caattatatc agaggctatt aaatcaatgg ccaaagctta tgctccttat tctgatttta
     1621 aggttggagc tgcgttagta actgaagata aaaaattttt tctggatgta atatagaaaa
     1681 tgctgctttt tctcctactt gctgtgcaga acgagtatct ttttataaag ctgtatttaa
     1741 aggagaacgt tcgttttcaa gaatatgtat tgtaggtgga aaaaatggta tcttatcatc
     1801 ttttatagca ccttgcggag tgtgtcgcca ggtaatgata gaattttgta attctgattc
     1861 atttgaagtt atattggcta gtgatgttga tacttataaa gtatataaac ttaaagaact
     1921 actaccagtt agttttaatc aagaaaattt ataacaggag ggaactatgg aattagttga
     1981 atttaaaaat ggacatgtta atacggttca tgagcatatc gcaataacga aagtaaaaga
     2041 gtttctaaat aatcatgata taccaaaaga taaaggtggc atacataaaa tttctactga
     2101 tttcttttac aatataattg atatggaaac tacaactgaa gagaatagac cgtgggaaag
     2161 tcataaggaa tattatgatg tccattatct gttaaatgga gaagaaataa ttttatataa
     2221 tttcttgtct caaatggaat tgtctgaata taaagtagat gatgattggc aacaaatgaa
     2281 tgggacagct ttatttagta ttaaattaaa gaaagatatg ttacttttgt tggaaccaaa
     2341 cgatgcacat aaaacaggcc tattggttga agaaccactt aatattaaga aagttgtttt
     2401 taaggtaaaa atttaactga aagtactttc ggggattaag aattttaaaa tatttaagaa
     2461 attgtattct aaagttctaa aattatagat atttaattta aagcttgtta aaatagaata
     2521 gt
//
LOCUS       DBEJKC010000105         2255 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.105, whole genome shotgun sequence.
ACCESSION   DBEJKC010000105 DBEJKC010000000
VERSION     DBEJKC010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2255
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.105"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..1586
                     /locus_tag="ACL3G6_002015"
     CDS             <1..1586
                     /locus_tag="ACL3G6_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0546473.1"
                     /translation="FSLLTIFIVAGQLLLIYAATINALVLNELIAMNLERFLKLSIYQ
                     MIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHSKSSGTYLSWLN
                     NDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLMIMLLVPKIFAS
                     KMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAGILLKMVIQRKT
                     TVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTGVIFTALGELGG
                     QLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNICYKYGDKEILKN
                     LNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIKKTSYLNMVSNV
                     LYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNILDYYVGDDGRL
                     LSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDREDLTVIIVTHAP
                     HPELKQYFTKIYQFPKDFI"
     gene            1935..>2255
                     /locus_tag="ACL3G6_002016"
     CDS             1935..>2255
                     /locus_tag="ACL3G6_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546474.1"
                     /translation="MSDIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPSTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKY"
BASE COUNT          800 a          257 c          408 g          790 t
ORIGIN      
        1 aatttagttt attaacgata tttattgttg ctggtcaatt attgctaatt tatgcagcaa
       61 ctattaatgc tctggtgttg aatgaattaa ttgcgatgaa tttagagcgg tttttgaaat
      121 tgtcaatcta ccaaatgatt gtctggtgtg ggataatatt ccttgactgg gtagtgaaaa
      181 attatcaggt tgaagtgatc caagagttta atctagagat tcgaaataga gttgccacag
      241 acatctctaa ctctacctat caagaatttc atagtaaatc atcaggaaca tatctttcgt
      301 ggctaaataa tgatgttcag actttaaatg atcaggcttt taaacaactt tttttagtaa
      361 taaaaggaat ttctggtact atatttgcag ttgtgactct taatcactat cattggtcat
      421 tgactgtagc caccttgttt tcattaatga ttatgctact tgtaccaaaa atctttgcat
      481 cgaaaatgcg agaagttagt ctaaatttaa ctaaccaaaa tgaagctttt ttaaaatcta
      541 gtgagactat attgaatgga tttgatgtgt tagcatcctt gaatctttta tatgtattgc
      601 ctaagaaaat taaagaagca ggaattttat taaagatggt tatacaaaga aagacaactg
      661 tagaaacgtt agcaggcgct attagcttct ttctcaatat tttttttcag atatctctcg
      721 tttttttaac aggctatctt gcaataaaag gaatagtgaa aattggtact attgaagcaa
      781 taggagcact aacaggtgtt atttttacag cgctaggtga attaggaggt caattatcct
      841 ctattattgg tacgaagcct atttttttaa aattgtattc aattaatcca attgagtcaa
      901 ataaaatgaa tgatatcgaa ccaaatgagg tgaatagaga ttttccgtta tatgaagcaa
      961 aaaatatttg ctataagtat ggagataaag aaatattaaa aaacttaaat ttttgttttc
     1021 aacgtaatga aaagtattta attttaggtg aaagtggaag cgggaaatct acattattaa
     1081 aattattgaa tggctttttg agagattata gtggagaatt gcgattctgc ggggatgata
     1141 taaaaaaaac ctcctattta aatatggttt cgaatgttct atatgtagat caaaaagctt
     1201 atttgtttga aggtacgatt agagataata ttttattgga agaaaattat actgatgaag
     1261 aaatactaca gtctttagag caagttggtt tgagtgtaaa agattttcct aataacattt
     1321 tagattatta tgttggtgat gatgggagat tactgtcagg agggcagaaa caaaaaatta
     1381 ctttagctag agggctaatt agaaataaga aaatagtatt aattgacgag ggaacttctg
     1441 ctatcgatag gagaacttcg ttagcgattg aacgtaagat attagataga gaggatttga
     1501 ctgtcattat tgttacccat gctccgcatc cggaacttaa acaatatttt actaagatat
     1561 atcaatttcc aaaggatttt atttaagaat ataggggagg gaaacatgag attctattgt
     1621 gaagcttatg aggtaattac tgaagagaaa aaagtatact ttaatgatat tgagttagaa
     1681 gttaagtatt cctctgtcga agaattgttt ataatatgtg agaaattatt agataagaaa
     1741 aaagtatcat ttttttatgt agatgagaaa cccttaaggt atctgttatt tgactatata
     1801 tttctactag ttctagctaa aaaaatatcc caatcttatg aactgcaccc caaaagttag
     1861 atttattctg tctaactttt ggggtgcagt tcattttgca tagttttggc attcatccta
     1921 gatatccata taaaatgtct gatattgttg aaatgtctaa aaaaatatca gatctaaacg
     1981 ataaaaaaga atttcacaaa aagaactgtg agttgaggtt tcaagatagt gttcttgata
     2041 acataaatag tgtcccgagt acaactcatt tatttagttg tttaaatatt caaacattag
     2101 taaaaattat tttatatatt tttcgataca acagttgtat gaaaatattt aattttagag
     2161 ataaagagct tatctttttt aataagattg taaatgggct gatacaaaat attgaggaga
     2221 atttagagga tgatattgaa aggatattga aatat
//
LOCUS       DBEJKC010000106         2230 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.106, whole genome shotgun sequence.
ACCESSION   DBEJKC010000106 DBEJKC010000000
VERSION     DBEJKC010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2230
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.106"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..915
                     /locus_tag="ACL3G6_002017"
     CDS             <1..915
                     /locus_tag="ACL3G6_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGR0546475.1"
                     /translation="FILLIGDESYSFSTLIKVLNSETVPGASFSIMEIRLPKLLAGII
                     AGWSFGLAGFIFQTMLRNPLASPDIIGVTSSSSIAAVFCILVLKTNSLTTGIISITCG
                     LTSSLILFLLAKKDGFSAARLIILGIGFQAVTRAGTSFLLLKVARYELQEVMRWLSGS
                     LSFTKLDDIPLVLIVSIIATILVLFFNKRLEIIELGEEIAIGLGANPELSRLVLIFCA
                     VSLTAFSTSITGPIACISFLAGPIALNIGKKRSPILAGLVGILLVLLSDIFSQNILPA
                     RYPVGVVTGLLGSPYLIYLLIKMNRRNI"
     gene            915..1709
                     /locus_tag="ACL3G6_002018"
     CDS             915..1709
                     /locus_tag="ACL3G6_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0546476.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
     gene            1860..2044
                     /locus_tag="ACL3G6_002019"
                     /pseudo
     CDS             1860..2044
                     /locus_tag="ACL3G6_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612340.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          825 a          335 c          368 g          702 t
ORIGIN      
        1 ttcattttac ttatcggaga tgaaagttat tctttttcaa ctttgattaa agtcttaaat
       61 agtgaaactg ttcctggagc tagtttttcg attatggaaa ttagattacc aaaattatta
      121 gcaggaatta tagctggctg gtcttttgga ttggcaggat ttatctttca aactatgtta
      181 agaaatcctc ttgcaagtcc tgatataatc ggtgtcacaa gttcttcatc tattgcagcg
      241 gtcttttgca tattggtatt aaaaacaaat agtttaacta ctggaattat ttcaataact
      301 tgtggactaa catcatcttt aatattattt ttactagcta aaaaagatgg tttttcagca
      361 gcaagactga taatattagg tattggtttt caagctgtca caagagcagg cacctcattt
      421 ttattgttga aagtagcaag atatgaatta caagaagtta tgagatggct cagtggctct
      481 ttatctttta caaagttaga tgacatacct cttgttctaa tagtaagtat tattgctact
      541 atattagttt tattttttaa taaaagacta gaaattattg aacttggtga agaaatagca
      601 atcggacttg gagcaaatcc cgagctttca aggcttgttt taattttttg cgctgtatct
      661 ttaactgctt tttctacttc aattacagga ccaatagctt gtatatcttt tttagctggt
      721 cccatagcct taaatattgg caagaaaaga agcccaatat tagctggatt ggttggaatt
      781 ttactagttt tgttatcaga catattctct caaaatattt taccagctag atatccagta
      841 ggtgttgtaa ctggcttgtt aggttcacca tacttaatat acttactaat aaaaatgaac
      901 aggaggaata tataatgaaa ggtctgtggt caaataatct tacctgcggt tatgatgaaa
      961 aaataatctt ggaaaatata aatataaaaa tacctgaaga aaaaatatca gttattattg
     1021 ggtcaaatgg ttgtgggaaa tcaacactca ttaaaacctt gtctcgactt ataaagccat
     1081 tagagggaga agtattgctt gataataaat caattaattc ttataaagaa aaagatttag
     1141 caaaacacat agctatatta cctcaatctc caataatccc tgaatcaata acagtagctg
     1201 atcttgtaag ccgtggtcgt ttcccctaca gaaagccttt taagagtctt ggaaaagatg
     1261 accttgaaat aataaacaga tcaatggtta aggccaatgt tgaagatcta gcaaataacc
     1321 tagttgaaga actttctggg ggtcaaaggc aaagagtatg gatagctcta gccctagccc
     1381 aagatacaag tatcctactt ttagatgagc caactactta cttggatatc tcatatcaaa
     1441 tagaactatt agacctcttg actgatctaa accaaaaata taagacaacc atttgcatga
     1501 ttttgcacga tataaatcta acagcaagat acgctgatta cctatttgca attaaagaag
     1561 gtaaacttgt tgcagaggga aagcctgaag atatactaaa tgataaacta gttaaagata
     1621 tctttaatct tgaagcaaaa attatacgtg accctatttc caattcgcct ctaatgattc
     1681 ctattggcaa gcaccatgtt aactcttaat aattgaatat tggaattcat ttaaaagtcg
     1741 caaattttga actgaccctc aaaagttagg ccaaaaaact aactaaagga ggtcagtttt
     1801 ttaatggcaa atacagcaca gaatttaaga taaaattagt aaaagaatat catgaatgaa
     1861 aaataggata tagagaataa cagcaatatt aaaaagatca ggactgataa taaacaaaaa
     1921 gaaagtacaa cgactagttc aaaagctaaa acttcaagta aaaagttatt caagaaaatc
     1981 tagaaaatac tcatcctaca aaggacaggt aggaaaaata tcagacaaca aaataaaaag
     2041 aaatatttat taccgaaaaa aaggggaaat cgagttaagt accaacaggc tcatctattc
     2101 caaaaagata tttactcgat ggaaaaactc ctagaattag tgctacaaat attgacaatg
     2161 gtatcttagg ttactacgaa gatatagatg ataaaaatta tagagtcttt gaaaatttta
     2221 tatctgtttc
//
LOCUS       DBEJKC010000107         2112 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.107, whole genome shotgun sequence.
ACCESSION   DBEJKC010000107 DBEJKC010000000
VERSION     DBEJKC010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2112
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.107"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            487..738
                     /locus_tag="ACL3G6_002020"
     CDS             487..738
                     /locus_tag="ACL3G6_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000098314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546477.1"
                     /translation="MSSQMKAFLNELQGNMEVVGEFFDNPEKVIRKFGIVGREKEALL
                     IRDLNDMDDYALSIQNSVASPSGAHSSTCHFVRQDLQSA"
     gene            967..1269
                     /locus_tag="ACL3G6_002021"
     CDS             967..1269
                     /locus_tag="ACL3G6_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546478.1"
                     /translation="MKNKYDVKRIIPDELSESLDIFLKNYSETGLSDYNTYLFYGFIL
                     KSYKLPRENRYSIKLLVKELQNRGLKVTLIINIYYHALNCLALNDGLKIYEEDFLI"
     gene            1266..>2112
                     /locus_tag="ACL3G6_002022"
     CDS             1266..>2112
                     /locus_tag="ACL3G6_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HGR0546479.1"
                     /translation="MNYEKYLNYLDYETEIEDAYHNLLLEYKISDNFSDEHWLYNLPS
                     NITQSKGFKIHLSASILNANLVAKKFFDFIFSREKKINFKILVSIKELSLQNTGLNGY
                     SQVGKFITIYPKDNKEFQRLLHKLEILYKGVKGVNIPSDFRFQLSEVVYYRYGEFVKD
                     STFKDKRDKKIPSNVNVPIRDYYIPRYNTIPDQYIILEVISKNAKGGVYKVFNTQKRV
                     YSLLKEASDLSLVDFTNRDSVNRLINEREILVELEKEEFTPKVFNDFYIKNSYFVEFE
                     FIIADK"
BASE COUNT          791 a          218 c          370 g          733 t
ORIGIN      
        1 taattttgaa gtgataaaat aaatgcaaga aaacgaaagg agaggtatat gagaagtttg
       61 tttaggaaaa ttgttgcttt gttagtcata ggattaatcc tattagggac tgctggagga
      121 actcaagttc ataagatggc tagagggatt gatcaaggtc ctgcgaatgg tatttataga
      181 taggagatta tagtcactta aaaatcaaca aattataaaa tttttgtttt acttaaatag
      241 atattttatg atgggcgaag tttttataac tagttcctat aagtacagaa acctatttta
      301 atttactaat ttcaaaacaa ttttttgaga tatatgtaat taaatctaaa ttaagcttta
      361 aaaaattatt tttagcaatt tgattttgaa agtgtcatgc agcaatatga aagcgtagaa
      421 tagaggtgtt tccaatgtac aagtaagttt tgattccaaa taaagtaata gaaaaggagc
      481 tatataatga gtagtcaaat gaaagctttc ttgaatgaac ttcaaggaaa tatggaagtt
      541 gttggagaat tttttgataa tcctgaaaag gtaattagaa aatttggaat tgtcggaaga
      601 gagaaggaag cattgctaat ccgtgactta aatgatatgg atgattatgc tctttcaatt
      661 caaaatagcg ttgcatcgcc ttctggggca catagtagca cttgccattt tgttagacaa
      721 gatttacaat ccgcataatt gttaatatat aaaacataaa atttcaattt tcaattaggg
      781 ataatagaat tccttactat gatatagaaa gtgaattaat taggaaatct tagtcagagg
      841 tttctgatta attcattttt tatatattaa gagtgatgtg aaatgttcaa attgtgagac
      901 tactctcgga ttgttgtata gaaatttaaa attttattgt gagcttttta aggaagagtg
      961 gccgatatga aaaataaata cgatgttaaa agaattattc cggatgaatt atcagaatca
     1021 ctagatattt ttctaaaaaa ttattctgaa actggattgt cagattataa tacttatctc
     1081 ttttatggtt ttatcttgaa gtcctataaa ttgcctcgag aaaatagata tagcataaaa
     1141 ttattggtga aggaattaca aaatagagga ctgaaagtta cattgattat caacatttat
     1201 tatcacgctt taaattgttt ggctttaaat gatggtctaa aaatttatga agaagatttc
     1261 ttaatatgaa ttacgaaaag tatttaaact atttggacta tgaaactgaa atagaagacg
     1321 cataccataa tttattatta gaatataaaa ttagtgataa ttttagtgat gaacattggt
     1381 tatataattt gccgtctaat atcacccaat ctaagggatt taaaatacac ctgagcgctt
     1441 caatattaaa tgctaatttg gttgctaaaa aattctttga ttttatattt tctagagaga
     1501 agaagataaa tttcaaaatt ttggttagca ttaaagaact ttctttgcaa aatacagggc
     1561 ttaatggtta ttcacaagtc gggaaattca ttacaattta tccaaaagat aataaagaat
     1621 ttcaacgttt gttacacaaa ttagaaatat tgtataaagg tgtaaagggt gtaaacatac
     1681 catcagattt cagatttcaa cttagcgagg ttgtatatta cagatatggg gagttcgtaa
     1741 aagatagcac tttcaaggat aaaagagata agaaaatccc ttcaaatgtg aatgttccaa
     1801 taagggatta ctatattcca agatataaca ctattcctga tcaatatatt attttggaag
     1861 tgatttctaa aaatgccaaa ggtggagttt ataaagtatt taatactcaa aagcgagttt
     1921 attctttatt aaaagaagct agtgatttat cgttggttga ttttacaaat agagattctg
     1981 tgaatcgttt aataaatgaa agagaaatat tagtagaatt ggaaaaggag gaatttactc
     2041 caaaagtttt taacgatttt tacataaaga attcgtattt tgtggaattt gagtttatta
     2101 ttgcagataa at
//
LOCUS       DBEJKC010000108         1842 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.108, whole genome shotgun sequence.
ACCESSION   DBEJKC010000108 DBEJKC010000000
VERSION     DBEJKC010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1842
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.108"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..698
                     /locus_tag="ACL3G6_002023"
     CDS             <1..698
                     /locus_tag="ACL3G6_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase M50 family protein"
                     /protein_id="HGR0546480.1"
                     /translation="FNKNFEKILFGIFPLALILQCFIMYIYRADILTNFQNFPITLNI
                     LLFWLLVVIISATIHEFSHAIIANNYQIEIPNCGIMLLLFNLAFFVDLSGVQFLKNKK
                     QFLKIMLAGIASNSILSLTGLLVLLFTSYKLLGLLFFIINLGMIFINSIPFFQYDSGI
                     ILRYLNSNNNNLNFQYIVQLLIAFVIIYFPLSQLLQFLTPNIIVRSIGGVVVSILLSI
                     LYMIGRTKYVLRK"
     gene            959..1768
                     /locus_tag="ACL3G6_002024"
     CDS             959..1768
                     /locus_tag="ACL3G6_002024"
                     /inference="COORDINATES: protein motif:HMM:NF013094.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HGR0546481.1"
                     /translation="MQNKTVLVLGAGALGCYISLSLSMYGVRKLIVADYDIIEPSNLN
                     RQILYTESDVGKEKINVLSEKIHKYNSDVQVVPISIKVSSLEELEKIVAEYGSIDFIV
                     KAIDTPIDIIKIVNQFAVSHKISYISGGFNGCYLIIDNIYIPTIGSCFGCRNINKDIN
                     KYTLSDKTKWPTTPEMPAILGGIMTNLIIKIFLGCYNETLIDNAYVYNMRNHALSQEK
                     YVLENGECPICKKNNKVKDNNIRAKTFIRSVCFCLLSGGVAFYLLLGSSLL"
BASE COUNT          633 a          215 c          305 g          689 t
ORIGIN      
        1 gatttaataa gaattttgaa aaaatcctat ttggtatttt cccattggct cttattttgc
       61 aatgttttat tatgtatatt tatagggcgg atattttgac taatttccaa aactttccaa
      121 taacgctaaa cattctttta ttttggttgc ttgttgttat tatatctgca acgatacatg
      181 aatttagtca tgcaataatt gctaataatt atcaaattga gatcccaaat tgtggaataa
      241 tgctactttt gtttaatttg gctttttttg tagatttaag tggggtgcaa ttcctaaaaa
      301 ataaaaaaca atttttgaaa attatgttag caggaattgc ttcaaattcg attttatcac
      361 ttacaggttt acttgtttta ttgttcacat cgtataaatt gcttggactc ttatttttta
      421 tcattaactt aggtatgatt tttattaatt caattccttt ttttcagtat gatagtggta
      481 ttattttaag atacttgaat tctaacaata ataacttgaa ttttcaatat atagttcaac
      541 ttttaatagc atttgttatt atttatttcc ctttgagtca actattacag tttttgacac
      601 ccaatattat tgttcgtagt ataggagggg tggttgtttc tatactgctt tctatattat
      661 atatgatagg aaggacgaaa tatgttctac gtaaatagtt atgtttttgc ttataaaaaa
      721 gaaggtataa tgtatttacg tggtcggagt atgcgggaaa tagctataga acctcaaatt
      781 tcgcaagaat ttatcaacga tcaaggaact attagagata gaagaagtat taggcagtaa
      841 actaacattt gaactattaa atgaacaaat tttaatttcg gatgagatag atattgatag
      901 tagatattct agaactaaag gttactattc gttattttat aatgaagagt ataataaaat
      961 acagaataaa acagtattag tattaggagc aggagcctta ggatgttata tatctttaag
     1021 tctaagtatg tatggagtga ggaaacttat tgtcgctgat tacgatataa tagaaccatc
     1081 aaatttaaat aggcaaattc tttatacaga gtcggatgtt ggtaaggaga agattaatgt
     1141 tctttctgaa aaaatacaca agtataattc agatgttcag gtagtaccta tttctattaa
     1201 agtttcttca ttagaagaat tagaaaaaat tgttgcggaa tatgggagta tagattttat
     1261 cgttaaagca attgatacgc ccattgatat tataaaaatt gtcaatcaat ttgctgtatc
     1321 gcataagata tcctacatat caggagggtt taatggatgc tatcttatta ttgataatat
     1381 atatatccct accatcggtt cttgctttgg ttgtcggaat ataaacaaag atataaataa
     1441 gtacacttta tctgataaga caaagtggcc gactacacca gagatgcctg ctattttggg
     1501 agggataatg actaatttaa taattaaaat atttctggga tgttataatg aaaccctaat
     1561 agataacgct tacgtttata atatgagaaa tcatgctcta agtcaagaaa aatatgttct
     1621 ggaaaacgga gaatgtccaa tttgtaaaaa aaataataaa gtgaaagata acaatattag
     1681 agcgaaaaca tttattcgtt cagtttgttt ttgcttatta tcaggaggag tagcttttta
     1741 tctgctattg ggcagttcac tgttatagaa acacaattaa tagtattgtt cttgggtatt
     1801 atttttgcta tatattatgc ttactacaat aaaaatattc aa
//
LOCUS       DBEJKC010000109         1733 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.109, whole genome shotgun sequence.
ACCESSION   DBEJKC010000109 DBEJKC010000000
VERSION     DBEJKC010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1733
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.109"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            33..484
                     /locus_tag="ACL3G6_002025"
                     /pseudo
     CDS             33..484
                     /locus_tag="ACL3G6_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            649..948
                     /locus_tag="ACL3G6_002026"
     CDS             649..948
                     /locus_tag="ACL3G6_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HGR0546482.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            1209..1532
                     /gene="tnpB"
                     /locus_tag="ACL3G6_002027"
     CDS             1209..1532
                     /gene="tnpB"
                     /locus_tag="ACL3G6_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR0546483.1"
                     /translation="MIIQLSDLGQVHLVCSKIDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDDQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPQI"
BASE COUNT          578 a          335 c          308 g          512 t
ORIGIN      
        1 taataacgat actagataat gaggaaaatg caatggcaaa cccaactctc ggagaaaaaa
       61 agcgaataca gactatattg ctcgctatgg cgtatatgca gttatcccta atcctgaaca
      121 aaaacaaatt gttcttgttc aagaaccaaa tggtgcttgg ttcctaccat gtggagaaat
      181 tgaagcaggt gaaaatcatc aggaagccct aaagcgtgag ttgattgaag agcttggttt
      241 cacagcagaa attggtacct attacggaca aactgacgaa tatttctatt ctcgtcatcg
      301 tgatacctac tactacaatc ctgcctacct ctatgaagca acttctttca aagaagtaca
      361 aaagccacta gaaaacttta atcatattgc ctggttccct attgacgagg ctatccaaaa
      421 ccttaaacgt ggtagccata aatgggccat tgaatcttgg aaaaaacagc ataagattgg
      481 ctaatactct tcgaaaataa aattcaaacc acgtcagcgt cgccttaccg tactcaagta
      541 tagcctgcgg ctagcttcct agtttgctct ttgattttca ttgagtataa atcaagcgac
      601 tttattcaaa aagtgctata atagaattag aaaatcggag gaaatattat gaagcttatc
      661 aatacgacaa actcacactc gcaacttgta aaaagtcaac tagaaagtac cgatgcaacc
      721 cttgttgagg tttattctgc agggaataca gatgttattt ttacccaagc tccgcttcac
      781 tatgaaatcc tcatctcaaa caaacaccgt gctattcgtg agcctgaaat cgaaaccatt
      841 caagaatttt tcttgaaacg taaaattgat aaggcctctg ttgatgaagc caatatcaag
      901 acactctact cagagaaatt aattggaatt tcaatcccaa tcaagtaaga aaattgagta
      961 aaaactcgat ttgagagaaa gtccaataag tctttccata acaaaacgca tagtaacaag
     1021 agtttctaca cccactatta tacgttttta tcattttgaa atctgctgct aatcaatgaa
     1081 gaagcaaaga tcaaactaag cagctagtta caagttacgt aagcgcgtca taacaaggta
     1141 tctatcctaa ttccccaact tccagtatac tagataaaaa ataattatcg gaggaaaggt
     1201 attgtactat gataattcaa ctaagtgatt taggtcaagt tcaccttgtt tgtagcaaga
     1261 tagatatgag gcagggaata gactcattag cctatgtagt taaaacccac tttgaattgg
     1321 atcctttctc cggtcaagtc tttctctttt gtggtggacg taaagaccgc tttaaagccc
     1381 tttactggga tgatcaagga ttttggctac tatataaacg ctttgagaac ggcagactga
     1441 cttggcccag tacagaaaag gatgtcaaag ctctcacacc tgaacaagta gactggctta
     1501 tgaagggctt ttctatcact ccccaaatat agtggattta aactagaata gtacacctct
     1561 gcttctaaaa cattgttaga aatcgatttg actgtcctga tcgatttgtc ctgttcttgt
     1621 ttcattttac tatagaacga tttgaaggcg tttataatat ttagctgtac gagagtcttt
     1681 aaaagtgttt tgatggtttg gatttcttct ttagttgatt tcatatcact att
//
LOCUS       DBEJKC010000110         1722 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.110, whole genome shotgun sequence.
ACCESSION   DBEJKC010000110 DBEJKC010000000
VERSION     DBEJKC010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1722
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.110"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(657..1649)
                     /locus_tag="ACL3G6_002028"
     CDS             complement(657..1649)
                     /locus_tag="ACL3G6_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0546484.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
BASE COUNT          597 a          278 c          216 g          631 t
ORIGIN      
        1 acttgatttt ggagtagtta taaaaactca ttcagataat ttattatttg attttgatac
       61 gattcctgaa aatataatag tagttgacca ttttgaactt acaatcgaaa aatggttaag
      121 taaaagtcaa cagttactat agtttgcaaa ttatttacag aaagaacaaa aatgctctga
      181 aacactgatt tcaaagcatt tttttgttag tttaaaatta ctcccattct tcttttccaa
      241 acgtacaata tatccaaaac cattcaaaat actagattct attttttata atatcactaa
      301 atccacctaa ttataggacg ttttcagatt tttagtcccg tcccagtccc agtaccggag
      361 aaatattgtt ttaatataat atctcttttt gtcttctaag ctcttaaaag caaaagaaca
      421 agtaaagagt caagacaagg ataaaaagtc catattaggg caaataaaaa gctttaagac
      481 agatgacaaa tctaagtcaa ataagaaaga ccatagcaaa ggtgcagaga gataaatatt
      541 ggcggtcttc ggactgcctt tattttttta tccatttttc aaatcaaatt tattcagact
      601 atatatgcac atatacactt aaattcatat aaaaacatgg cttgtaaaaa attactttaa
      661 tcacaataat cgcatttaaa attgtgatgt ttgcaagcta aattacggac ttcacttgga
      721 agttttccct tgtatctttt ataatagata gaaaatttgc tggcagatga atatccaaca
      781 gattctgcta tctcttttat aggtagttca gtgtttaaaa gaagagtttc agctacattc
      841 attctttttc tttgagtgta ctctgtaatg ctttgacaat atttttcctt aaataaattt
      901 tttaatttag taccactcat tttagatatt ttttcaagcg tgccttgatt tacattcgtt
      961 gcaaaatgat catctaagaa tcttgctaca tcttcaagtg ctttatcatc atcaatttca
     1021 attttatatt tttttctatt taagtatgtg tcaattacta tacttatcca ttcatttgcc
     1081 tttgctttaa agaaaaaatc agcggcagga gcgtccatct tacaatttaa tatttccatt
     1141 gccactcttt ctaaggcctt tgtaagtatt atttgattcg gttgaagcaa ggttgaataa
     1201 aaagattctg gattaatgtt aatagatgct aaatgttttt ctattagctc ttttttaaaa
     1261 ccaatggaaa cagcaagata acaacaattc tcgtgtaata aaaaaacaaa atcatctttt
     1321 atattatcaa aatcaaaagt acatagagag tttgcggtaa tagtttgata cggattaaac
     1381 ttttctccgt ttgcactgac aatgtaactt gaataaattg aaacatagtc tgacatacta
     1441 taagtgctat tttgaactac ttcctctttg atataaaaat catgtatatc gataatgaag
     1501 ctgcctcctt cataaaacca atataggcct tctgcataag ttgaattctc ttttttccaa
     1561 caaaatgtat gacctgcact tgaatacttc tcattgtttt tacattcatc tactttcata
     1621 taatctttta caaaatcata atatgacata acacactatc ccttttagac aatattccaa
     1681 ttagccttat taattcaaaa ctattgtatt agtaattata ac
//
LOCUS       DBEJKC010000111         1644 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.111, whole genome shotgun sequence.
ACCESSION   DBEJKC010000111 DBEJKC010000000
VERSION     DBEJKC010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1644
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.111"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            39..662
                     /locus_tag="ACL3G6_002029"
                     /pseudo
     CDS             39..662
                     /locus_tag="ACL3G6_002029"
                     /inference="COORDINATES: protein motif:HMM:NF021048.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
     gene            659..>1644
                     /locus_tag="ACL3G6_002030"
     CDS             659..>1644
                     /locus_tag="ACL3G6_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HGR0546485.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGSDM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKI"
BASE COUNT          685 a          210 c          262 g          487 t
ORIGIN      
        1 taacaagagg atagaaatga ccgaattaga aagaaaaaat cgaaaaatta gctaagaaat
       61 attctgataa cttaaacatc aaagttcaag agagagttcg tgaaatggca aatgataata
      121 agagccatta tttgatatac agagttttag gtatttcatt tgaagaagga gaaaatatcg
      181 atttgtatca aaataaaggt cgttttttat acaaatatgc tggttaattt ttagaagaag
      241 ctgcagtact atcctttaac gaaaaatttg gtacagaaaa tacttaaaaa gttaacattc
      301 ctaattctga aagtacaaaa cctaagactt ttgaaattga ttgtttagtc ggaaaaaaac
      361 acgcatacga aataaaatgg tgggatgcaa ctacagatgg agaccatata actaaagaac
      421 acactagaat aaaagttatt cataacaaag gatatatacc aattcggtta atgttctact
      481 atccaaatag aactcaagct ataaaaattc agcaaacttt agaaacattg tataacggta
      541 ttggagggaa atattattat ggagattctg cctgggaaca tttaagagca gtgaccggta
      601 ttgatttact tagtattcta acagatattg caaataaaaa aacaggggta aaatcaaaat
      661 gacagtatta aaaggagata acttagaaat attaaaaact attgaatcct caagtattga
      721 tttaatctat atggaccctc ctttctttac acagaaaacc caaaaattat ctaataacaa
      781 aaatattatg tattcattcg aagatacgtg gacttcgatt gaggattaca aagaattttt
      841 gtctgtaaga ttagaagaat gcaaaagagt gctaaaaaat agtggcagca ttttcgttca
      901 ttgtgataaa attgcaaatc atcatattag attaatttta gataatatct ttggatcaga
      961 tatgtttcaa agcgaaatta tatggaacta taaacggtgg tctaattcaa aaaagggatt
     1021 attgaacaat catcaaaaca tttactttta ttcaaagtca aaagatttta aatttaatac
     1081 aatttttaca gagtattctt ctactacaaa tatcgaccaa atactagtgg aacgaaaacg
     1141 agatggaaac tctaaaacta tatataaagt tgataataat ggtaactata ttctagcaaa
     1201 agagaaaaat ggagttcccc tttcagatgt ttggaatata ccatttctta atccaaaagc
     1261 taaagaaaga gtaggttatc ctacacaaaa acctattctg ttattagaac aaattataaa
     1321 gattgctact gataaaaatg atatagtttt agacccgttc tgtggaagtg gaactacttt
     1381 agtagcctcc aagattttga atagaaatta tatggggatt gatttatctg aggaagctat
     1441 caatataact cagcaacgtc tggaaaatgt tataaaaaca agttcaaatt tattgaataa
     1501 aggaatcgaa gcatatagaa ccaaaactga ggaagaggaa aacattctta aattattaca
     1561 ggcaaaaatt gttcaaagaa ataaaggaat tgatggtttt ttacctaaac attttcaaaa
     1621 aaaaccgata cctataaaaa ttca
//
LOCUS       DBEJKC010000112         1590 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.112, whole genome shotgun sequence.
ACCESSION   DBEJKC010000112 DBEJKC010000000
VERSION     DBEJKC010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1590
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.112"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..>1590
                     /locus_tag="ACL3G6_002031"
     CDS             <1..>1590
                     /locus_tag="ACL3G6_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0546486.1"
                     /translation="RNGSDFSVIIVNCLLAVVCKKINSSSTKLLPEFSGLDFSLWQDY
                     IQSTGSIKELWPSQIELGKQGIFSGKSGIVQMPTSSGKTASINLTLRSAFYSNRIDNA
                     LIVAPFRALCREIYRDINAHFVDENNVIVSEVFDLPEIPQDFSIFNDGKKRVFILTPE
                     KLLFLLRNHQSFIDEIGLCIFDEAHLFDDPSRGTNFELLLSTVKQIFPKGIQKILISA
                     VIPNSEAINRWFNEDGVIVSNNSIKTTEKRVAFSDLNGSNEQLYFIDPITFEEEFFVP
                     RTVSVSELEQLGKERKQKVFPELTNANDISIYYGTKLINNGGVGIFCGRKDTVNVILR
                     RFIDLNNRNYDLTDFLKNSDRSEVEKIGNLIGQNLGYDSVEYTCSQLGVFSHHSGIPM
                     GIRIAIEYAFSKSKINNVVCTSTLAQGINLPIKYLIISSVYQAGDAIKVRDFQNLIGR
                     AGRAGKYTEGTIILTEPNIYKSPKNKWKKQNYKALLNPINTEGCQSNILSIIQFKSVV
                     PTDYRFAPIKFDFWNLIKERF"
BASE COUNT          584 a          189 c          292 g          525 t
ORIGIN      
        1 ataggaatgg aagcgatttt tctgtaatta ttgtaaattg tctcttagca gttgtatgta
       61 aaaaaataaa tagttcatca acgaaattat tacctgaatt ttcaggatta gatttttctt
      121 tatggcagga ttatatacaa tcaacaggaa gcataaagga gctttggcca tctcaaatcg
      181 aattagggaa gcaaggaatt ttttcaggta aatctggaat cgttcagatg ccaacaagtt
      241 cgggtaaaac agcctcaatc aatctaactt taagatcagc attttattca aatagaattg
      301 ataatgcatt gattgttgca ccttttagag cattatgtag agaaatatat cgagatatta
      361 atgcacattt cgttgatgag aataatgtga ttgttagtga agtttttgat ttaccggaga
      421 ttccacagga tttctcaatt tttaatgatg gtaaaaaaag agtttttata cttactccag
      481 agaaattgtt gtttttattg agaaatcatc aaagttttat tgatgaaata ggactttgta
      541 tatttgatga agcacatctt tttgatgatc caagtcgtgg aaccaatttt gaattactgt
      601 tgtcaacggt taaacaaatt ttcccaaaag gaatacagaa gattttaata tctgctgtaa
      661 taccaaatag tgaagctata aatcggtggt ttaacgaaga tggagtaatt gtttctaata
      721 attcgattaa aacaacagag aaaagagttg cgtttagtga tttaaacggg agtaatgagc
      781 aattatattt catagatcct attacatttg aagaagaatt ttttgttcca cgtactgtta
      841 gtgttagtga attagagcag cttggaaaag aacgcaaaca aaaagttttt ccagaactga
      901 caaacgcaaa tgatataagt atttattatg ggactaagct aattaataat ggtggagtag
      961 gaattttttg tggaagaaaa gacacggtca atgttatttt acgaagattt atagacttaa
     1021 ataatagaaa ttatgatcta actgatttct taaaaaactc agataggtct gaagttgaaa
     1081 aaataggaaa tttaattggt caaaatttag gatatgatag tgttgaatat acatgtagtc
     1141 agctaggagt tttttcacat cattcaggta tacctatggg gatacgcatt gctatagagt
     1201 atgctttttc aaaaagtaaa ataaataatg tagtatgtac ttcaacctta gcacaaggta
     1261 taaacttacc tattaaatac ttgattatct caagtgtgta tcaagcagga gatgcaataa
     1321 aagttcgtga ttttcagaat ttgataggta gagcaggaag ggctggaaaa tatacagaag
     1381 gaacaataat tttaacagag cccaatattt ataaatcacc aaaaaataag tggaaaaaac
     1441 aaaactataa agcattgtta aatcctatta atacagaggg ttgtcaaagt aatattctca
     1501 gtattataca gtttaaatca gtagttccaa ctgattatcg attcgctcct ataaaatttg
     1561 atttttggaa tttgattaaa gagagatttg
//
LOCUS       DBEJKC010000113         1460 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.113, whole genome shotgun sequence.
ACCESSION   DBEJKC010000113 DBEJKC010000000
VERSION     DBEJKC010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1460
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.113"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..559
                     /locus_tag="ACL3G6_002032"
     CDS             <1..559
                     /locus_tag="ACL3G6_002032"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0546487.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCN
                     QWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            616..1413
                     /gene="psrA"
                     /locus_tag="ACL3G6_002033"
     CDS             616..1413
                     /gene="psrA"
                     /locus_tag="ACL3G6_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HGR0546488.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
BASE COUNT          507 a          208 c          266 g          479 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagttg ggagtgggtg aggttaaacg atataacctc
       61 ctacattcaa agagggaagt ctccaaaata ttcaaatatt cctatatacc ctgtgattgc
      121 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccga
      181 aacagttcat agttaccaga aagaaagatt actaagagat ggtgatttaa tgtggaattc
      241 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgg
      301 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcgggag ttattaattg
      361 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
      421 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
      481 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
      541 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
      601 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
      661 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
      721 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
      781 aatttgcgac tacaaggagt aaataaatat ctggctttta ttggtcatga tgatttgaaa
      841 ttaaaatttg tcaaagtaca gcaaaaaccg tttttagaag atgtcattag ccatgctgat
      901 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
      961 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
     1021 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
     1081 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg ccgaagtggt
     1141 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
     1201 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttaga
     1261 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
     1321 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
     1381 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtggtca aactgactac
     1441 ctgctatttt tgtgattatg
//
LOCUS       DBEJKC010000114         1452 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.114, whole genome shotgun sequence.
ACCESSION   DBEJKC010000114 DBEJKC010000000
VERSION     DBEJKC010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1452
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.114"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            153..1331
                     /locus_tag="ACL3G6_002034"
     CDS             153..1331
                     /locus_tag="ACL3G6_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HGR0546489.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALFYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
BASE COUNT          541 a          253 c          211 g          447 t
ORIGIN      
        1 atttgtgtaa acatttgatt attttttatt atcaatatat aataaaaaga gaccagtaag
       61 taatgaaaag cttaaaaaga ttaacatcta catttatcca tagcaaaaaa tcataggatt
      121 ttaagaatct gacaactagg aagaaaacta atatgacctt atctaagaaa caattacaac
      181 taagagctaa aatactggaa acagtttaca cattaggtcc catttcacga attgaaatcg
      241 ctactaaaac aggaataaca cctgcaacaa ctagcagtat cacaaatgat ctgattaaag
      301 aaaatattct cttagaactt ggtgaagacg aacacgatac aagcgtaggg agaaaaaaaa
      361 tcctgctaga cattcaagct aaacgatttt actacattgg ttgtgaacta tctgaaaaac
      421 atttcacttt tgctttagga gataatctag gaaatatctt aaaggaagag aaagaaattg
      481 ttactaaaca gttaatccaa gaaaagggaa atcaactcat taaccagaca ctaaagcaat
      541 tcttaaataa ctgctctgat tatgaaatag aagcaattgg aatcgcgcta cctggtcgct
      601 atttagatga ttataaaata acaacaaaca atcctttatg gcaacatatc gacttagaaa
      661 tgattcaatc ccactttgat aagcctttgt ttttctctaa caatgttaac tgtatggcta
      721 taggtaaacg cctatttagt cgccaacaga atgaccctaa ttttgcttat tttcattttg
      781 ctagaggtat gcactgttct tatatctacg acggaaacat ttatgggaaa ggaaatctaa
      841 tgattggaga aatagggcat acagttgttt catctgaggg agaagaatgt agctgcgggc
      901 gcaagggatg cttacaaact tttgctggag aatcttggtt aatcaaaaaa tcaaaaattc
      961 tatatcatca atctccctat tctctacttc ctagtttagt caaaaatgcc gatgatattg
     1021 atatccaagt tattttaacc gcttatcaat taggtgacac tggaataatc acacttatcc
     1081 atcaagcctt attctatctt agtcaaacca ttttaaatat cagtatgatg attgactctc
     1141 aaaaaatcta cctacatagt cctttactaa caaatcaaca catcatccaa aaactatata
     1201 gtgaaatgaa ctacaaaccc aaactgctct ataatcgcct acctgaagtc attattgaac
     1261 cttacaatga ttttacagcc gcacactcag ctattgcact ttgtttgtat catacaattc
     1321 tacattctta attttctatt acatttaata aataggctaa aaagagggag tatatcataa
     1381 aaagcgaata aacctgtttt ctgaaaatca gaattctgtt ttgttcgctt tctttatatt
     1441 tggaattata ct
//
LOCUS       DBEJKC010000115         1429 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.115, whole genome shotgun sequence.
ACCESSION   DBEJKC010000115 DBEJKC010000000
VERSION     DBEJKC010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1429
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.115"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(62..457)
                     /locus_tag="ACL3G6_002035"
                     /pseudo
     CDS             complement(62..457)
                     /locus_tag="ACL3G6_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(902..1300)
                     /locus_tag="ACL3G6_002036"
     CDS             complement(902..1300)
                     /locus_tag="ACL3G6_002036"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0546490.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          398 a          285 c          225 g          521 t
ORIGIN      
        1 tgctggcctg tttcttaagc gcttttcctt ttctagggta aagcagatcc tgcttgcttt
       61 accccaattt tccatgatga atccaatagt aaatggttga aattcccacg ttaacccctt
      121 tagccataac catcatttca ggcaaaaatt tttggttatg atagtggaga atcttttcct
      181 ttagttcctt ggtcacgctt gatctcttga ccgagtgctt gcgattattt tcataagact
      241 gttgagcata gtcggcagaa taaacctctt tgaagcgccc ttttccaaga cattttcgga
      301 ctgtcctacg cttgatttta gtgtggatag tttgaggagc ttttccaagt agagaggcaa
      361 tttctctatt tgattttcct tcttttttcc atctttcgat taagcgacgg ctatcgattg
      421 tcaaatgttt accttttgta gtataattgt cttgcatttc tgtgcctttc ttgtgtttgt
      481 ggttgaacaa caagtataac acagaggtgt tttcttatgc ctacaagagc tttcattatt
      541 tccattttct tttggatttc actctattct gaaaaacttg tgtatattta ctgaagctag
      601 caagtcttac ctgtaaattt aatgaaagca acacaaaatc cgagagggga atctcggatt
      661 aatagataga gagtttttag tttaaataaa ttgtttaaaa tatcaacaac atcacttctt
      721 ttcttaacct gataagtctt gattcctaat tttggggcta cgattatatt gtcctcaata
      781 tcgtctagaa agacacaatt tctaggttat aactggtatt tatcaatagt tactcatata
      841 catcagtcca cctccatact tatgtgcgag cctctctttg tattatacct ccatactcac
      901 cttacagatt cttttggtaa taatatcttt gcctaatgta gagatagtct tgcaaagaaa
      961 aaacttcctt gtagccatgt ttctgataaa agtccggtgc ctggaactgg taagtattga
     1021 caaaggcaaa acaacaattt cgattcttag cttcactttc tgcctgttgc aatagttttg
     1081 aaccgattcc ttgccctcgc agttcctctt ttacaaacaa atactcgatt tctagccaat
     1141 ttccaaaagt ctctgctatc aaacctgcca ggagattgcc cttttcatct tcgacataaa
     1201 gattaagtgg ctcactttca gcctcttctc tttttgaacg gttataaaca cgaatcagat
     1261 tccctatttc ttgcgattta tgtgattcct tattttccaa tctaaagtat agtgaaatga
     1321 aataaaacat gcgcaaatcg attaaggaat ttaatctaat ttctaacaat gtcttagaaa
     1381 tcaaagtgta ctattttaac ttcaatgcac tatacatcta atactcaat
//
LOCUS       DBEJKC010000116         1258 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.116, whole genome shotgun sequence.
ACCESSION   DBEJKC010000116 DBEJKC010000000
VERSION     DBEJKC010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1258
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.116"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..166
                     /locus_tag="ACL3G6_002037"
                     /pseudo
     CDS             1..166
                     /locus_tag="ACL3G6_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="PcfB family protein"
     gene            293..1015
                     /locus_tag="ACL3G6_002038"
     CDS             293..1015
                     /locus_tag="ACL3G6_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HGR0546491.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIEKDIEIDKEREGEIDKKSTP
                     IFYGEFKNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEE
                     DKDKLRQKGLNKKMNYDVGESL"
BASE COUNT          599 a          164 c          219 g          276 t
ORIGIN      
        1 ctttaaagtc taatagttat aggctaaata aaaaagaaaa agaaagtatc caaaaacaaa
       61 taaagaaata caaagaccta tccaaaaaca aagataagac aaaagaaaaa ggaaagtaaa
      121 agaaaaagta aaaccaaaca aaaaagatat gaccagagaa atctaaaggg agtaacgaaa
      181 agttacaccc ttaaataacc ataataacaa gacttccgaa aaacagaagt ccagaattcc
      241 gaaaatcgga aatcaagaat ttcgattatc gaaaatcaag aaaggagcag atatggcaac
      301 aaacaaaaga tactattgga taaaattaaa agaagaattt ttcacagaca aaaggataaa
      361 aaggttaagg agaatatctg gaggagatac ctatacgata atctacctaa aacttctact
      421 actaagccta aaagatgagg gcaaactcta ttatgacgga gtagaaagtg attttataaa
      481 agagttagca ctaaccatag atgaaacaga cgatgatgta atggtaacag taaattattt
      541 aatcaatcaa ggcttattag aagttgtaac agaaaatgat gaatactacc taactgaaat
      601 accaaactta atcggatcag aaacagcctg ggcagagaaa aaaagaagat acagacaaaa
      661 taaacagagg acattgtcct taatgagtcc aacccatgtc cgacaagaga tagagaaaga
      721 tatagagata gataaagaga gagagggaga gatagataaa aagtccaccc ccatttttta
      781 tggagaattc aaaaatgtaa ggttaagcaa agaagaatat aaaaatctaa aagaaaaatt
      841 aaactcacac acagatataa tgataaataa actatccaga tacatggaaa gcagtggtaa
      901 gacctatcaa aaccactatg tgacaatatt aaaatggtat gaagaagata aagacaaact
      961 aagacagaaa ggtttaaata aaaaaatgaa ttatgatgta ggagaatctt tatagataaa
     1021 aagaggtgga aaggcactat taaagacttt aagtctaaaa aggtatcaaa gtatgccaga
     1081 gataaaaaaa tataaatatg acactttaaa ggcgattaga aaattaaaga aatgctagaa
     1141 gacttttaga tgacagttac caagagggtc taattttcac tgctacttat gcagtgggaa
     1201 ttgaaccttt ttatataagc aaattctatt tcaaaattgg ttaccaagaa agacttct
//
LOCUS       DBEJKC010000117         1239 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.117, whole genome shotgun sequence.
ACCESSION   DBEJKC010000117 DBEJKC010000000
VERSION     DBEJKC010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1239
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.117"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            341..1232
                     /locus_tag="ACL3G6_002039"
                     /pseudo
     CDS             341..1232
                     /locus_tag="ACL3G6_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220488.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
BASE COUNT          472 a          134 c          220 g          413 t
ORIGIN      
        1 gcttaatgta gttgtttagt tttaaaaaat tatgcaaagc tccatataca acacttaaac
       61 gagattaaag aatggcgaaa tcccctgatg cgcaagagat tagctgtctt ttttattttt
      121 taagtgataa agtcggagct taggtatcaa agcctatcaa attaaacaaa gaagcgatgt
      181 cttagatatt ttgaaaaaaa ttaataagca gaaaactctc tattattttg ttgtatagag
      241 ttttttgtta ataaaatttc acaaaatgac atttatacat tgcattaagt tagatatatg
      301 atataatatt gttaaaaaga ggcgcaactt tttaaaatta atgagaatca aagagaaaac
      361 caataatatt aatggaggaa taaaaaatgt aagttataaa tgtaagtaag cattatggtc
      421 attcaatcat tctcaaagac ataaattttg cacttaacaa gggtgaaatt gttggtcaag
      481 tagggagaaa tggagttggt aagagtacgt tgatgaaaat tcttgttcag aataatcaac
      541 cgacttcagg taatattata agcagtgata atgttgggta tttaatcgaa gaaccaaaat
      601 tatttttatc taaaacaggt ttagagaatt taaaatattt gtcaaattta tatggtgttg
      661 actacaatca agaaagattt agaagtttga tccaagagtt agatttgact cagtctatta
      721 ataaaaaagt aaagacctat tctttgggta caaaacaaaa attagctttg cttctaactc
      781 tcgttacgga acctgatata ttgattttag atgaaccgac taatggttta gatattgaat
      841 catcacaaat agttttatcg gttctaaaaa atttagcttt acatgaaaat gtgggaattt
      901 taatatcgag tcataaatta gaagatattg aagaaatttg tgagagggtt cttttcttgg
      961 agaacgggct tttgacattt caaaaagtag gaaaagatag tcataatttc ttgtttgaga
     1021 tagctttttc atcagctaca gatagagaca ttttcattac caaacaagaa tttggggata
     1081 ttgttcagga agagggactg agaattacta tgtctgggaa tattcaaagt agtgagcttt
     1141 ttaaattttt taacgaaaac tctattaaag tagttgattt tgaaactaaa aaagagatgc
     1201 ttaaagatat ttatctaaat cgttcaaaat aaaggaagg
//
LOCUS       DBEJKC010000118         1138 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.118, whole genome shotgun sequence.
ACCESSION   DBEJKC010000118 DBEJKC010000000
VERSION     DBEJKC010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1138
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.118"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..290)
                     /locus_tag="ACL3G6_002040"
     CDS             complement(<1..290)
                     /locus_tag="ACL3G6_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HGR0546492.1"
                     /translation="MQIKFIDKVSNLIMLNLLYVASVVTVIAIGSGESALIATLIKIV
                     RHEESYPYRDFANSFFKDYWKNLGAALISNLPILILLFSLFFLPYIPLPIYI"
     gene            501..566
                     /locus_tag="ACL3G6_002041"
                     /pseudo
     CDS             501..566
                     /locus_tag="ACL3G6_002041"
                     /inference="COORDINATES: protein motif:HMM:NF013577.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            615..>1138
                     /locus_tag="ACL3G6_002042"
     CDS             615..>1138
                     /locus_tag="ACL3G6_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGR0546493.1"
                     /translation="MTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIEL
                     AIKLIREANQILMIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDL
                     IIAFSLSGSTKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGG
                     SLMAKASQLFIIDV"
BASE COUNT          447 a          124 c          194 g          373 t
ORIGIN      
        1 atgatatata taggtaatgg tatgtagggt aggaagaaca aactgaataa taagattaaa
       61 attggtaaat tagatattaa tgctgctcct aaatttttcc aataatcttt aaaaaaactg
      121 tttgcgaagt ctctataggg ataggattcc tcgtgtcgta caatttttat tagagttgct
      181 attagggcac tttcacctga tccgatagca ataactgtta ctactgacgc tacatagagt
      241 agatttaaca ttataagatt tgaaacttta tcaataaatt ttatctgcat ctttaactcc
      301 tgctgttttt atacttataa tatcacatca tttgagtttc atcaactttg aatacattaa
      361 gaaagaatat aactatgagg aaaggaaaaa attattatga ataaatccaa aaaatataaa
      421 gaaagaattc attatgaata cgataatctt actaaatcag agaaaaaatt gctgactata
      481 ttttagttag agatagtgaa atagtttatg aaacgtcttc agaaattgtt agtaaagtaa
      541 aagttggaga gggaactctt aatcgatttt gcaaaaagat tggatactct ggttttcagg
      601 aactaaaatt aaaaatgacg aaagatatat tagagttaga atctcaaaaa atgagtagtg
      661 acacatttat tgatgaaata aaaaataatt atttatctat tgtggaaagt acaagaaaat
      721 taattgatgg tagacaaata gaattagcta taaaattaat aagagaagca aaccagattt
      781 taatgattgg tgtgggttct agtggaaatg cggctagaga atttgagagt agtttgttaa
      841 gaattggaat aataagtaag acggtaattg atacccattt tcaactcatg catactgcgt
      901 tattgaaaga taatgatttg ataatagcgt ttagtttatc tggttccaca aaagaagttg
      961 aggaaacttt attaaacgca aaaagaaaaa atgttaaaat tatttcaata acaaattatt
     1021 cgtccagaaa tatagcaaaa ttatctgact gcgttctttt gacatcaaaa aaagaatctt
     1081 atttagaggg tggtagttta atggctaagg cttctcaact attcataatt gatgtaat
//
LOCUS       DBEJKC010000119         1099 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.119, whole genome shotgun sequence.
ACCESSION   DBEJKC010000119 DBEJKC010000000
VERSION     DBEJKC010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1099
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.119"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            473..>1099
                     /locus_tag="ACL3G6_002043"
     CDS             473..>1099
                     /locus_tag="ACL3G6_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HGR0546494.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     TLIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDM"
BASE COUNT          321 a          188 c          230 g          360 t
ORIGIN      
        1 tttgagcttt tttcttttta aatattgatt gtttctaaaa gttctagtaa tattgctatt
       61 tctcattttt ccaaatatgt tattcaactt attagctacg tctctattca tatttgggta
      121 taaaacaaaa aatcaattct aacagtttta tatcagaata ataaataaaa aagcgatatt
      181 ctagactgta tcaatccttt tccattatag gagcaacaga gtgggagtag tcatctaagg
      241 actaatttat gtatttttac gagtcagtat ctttggatac tggtttttac ttttctagac
      301 tttttgacta cttgttaaaa ctgggataat tttcgactgt ttaacagtta ttatgcaaag
      361 tctaaaagat tagaattgtc aaaacaatcc gtctaggctt gattttatcc tttatttact
      421 ataaaatgag aaggaaaaat gtcaaacttt tatattgcaa ataggagaaa ttatgacaaa
      481 aacattaaaa cgtcctgagg ttttatcacc tgcagggact ttagagaagc taaaggtagc
      541 tgttcagtat ggagcagatg ctgtctttat cggtggtcag gcctatggtc ttcgtagccg
      601 tgcgggaaac tttactttcg aacagatgga agaaggcgtg cagtttgcgg ccaagtatgg
      661 tgccaaggtc tatgtagcgg ctaatatggt tatgcacgaa ggaaatgaag ctggtgctgg
      721 tgagtggttc cgtaaactgc gtgatatcgg gattgcagca gttatcgtat ctgacccaac
      781 cttgattatg attgcagcga ctgaagcacc aggccttgaa atccaccttt ctacccaagc
      841 cagtgccact aactatgaaa cccttgagtt ctggaaagag ctaggcttga ctcgtgtcgt
      901 tttagcgcgt gaggtttcaa tggaagaatt agctgaaatc cgcaaacgta cagatgttga
      961 aattgaagcc tttgtccatg gagctatgtg tatttcatac tctggacgtt gtactctttc
     1021 aaaccacatg agtatgcgtg atgccaaccg tggtggatgt tctcagtcat gccgttggaa
     1081 atacgacctt tacgacatg
//
LOCUS       DBEJKC010000120         1053 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.120, whole genome shotgun sequence.
ACCESSION   DBEJKC010000120 DBEJKC010000000
VERSION     DBEJKC010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1053
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.120"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..559
                     /locus_tag="ACL3G6_002044"
     CDS             <1..559
                     /locus_tag="ACL3G6_002044"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0546495.1"
                     /translation="NKDETTSYPIYEIPKAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(507..>1053)
                     /locus_tag="ACL3G6_002045"
     CDS             complement(507..>1053)
                     /locus_tag="ACL3G6_002045"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0546496.1"
                     /translation="PMNWVVIKIKDIFSINTGLSYKKGDLSINKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT          379 a          168 c          154 g          352 t
ORIGIN      
        1 gaacaaagac gaaacaacct cttatcctat atatgaaatc ccaaaagcat ggagatatat
       61 taaatttgct agcctagtta acttcagaat aggaaaaact cctccacgca gtgaagctac
      121 tttttgggga actgaaatac cctgggtatc tatatcagat atgcctatat ctggttatgt
      181 aactaatacg agagaatcta tttctaaatt agcattaaaa tcaaagaaaa tagacatttc
      241 acctaaagga actttattaa tgagttttaa attatctatt ggaaaagttg ccatattgga
      301 tattcctgcc actcataatg aagccattat atcgatattc ccctatgcta ataaagaaaa
      361 tattatcaga gattacttaa tgatattttt gccacttatc tctactttag gtgattcaaa
      421 agatgctatc aaagggaaaa cattaaatag taccagtatc tccgaattat taatccctat
      481 ttctaatcat gaagagatga aaagaatcat ttccaaagtt gatttacttt ttcaaaaagt
      541 ttctcaactt tttgagtaat aagttcctgt tcctcaaaag gagctaacgg aattaatagc
      601 tcgcttagtg tagttttagg aatattatat aaagcttgac ctgatagttt agttattgct
      661 ttcaattgtt tataaaataa cggagaggac aagttaaata atagaaattt tgaaataatc
      721 tctgaacttt cgaatggtgt taattggaaa ataaatccac cagccacaac accatcatag
      781 tctttatcga ttcttgcaaa ctttccaata tgttctaaag aggttgatac aggtgttatt
      841 agctgattat gttttaaata aacttgctca gaggagatga attgtgtgtc aatgtagtaa
      901 tcattatcca acagagaaaa ttctaaaggc ttaatattac caccacgtat aattctaaca
      961 cctttattaa tgcttaaatc gcccttcttg taagaaagac ctgtatttat tgaaaaaata
     1021 tcttttattt ttataacaac ccaattcata ggt
//
LOCUS       DBEJKC010000121         1005 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.121, whole genome shotgun sequence.
ACCESSION   DBEJKC010000121 DBEJKC010000000
VERSION     DBEJKC010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1005
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.121"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            275..526
                     /locus_tag="ACL3G6_002046"
     CDS             275..526
                     /locus_tag="ACL3G6_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HGR0546497.1"
                     /translation="MKEFQFERKQRFSLRPYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            514..804
                     /locus_tag="ACL3G6_002047"
     CDS             514..804
                     /locus_tag="ACL3G6_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGR0546498.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
BASE COUNT          382 a          137 c          189 g          297 t
ORIGIN      
        1 ttatctacta cctcaaaaca gtgttttgag caacctgtgg ctagtttcct agtttgctct
       61 ttgattttca ttgagtacaa agagcttggc aacaggctct ttttgtattg cgtttattaa
      121 gaaaaacaaa aaacatcgat atacatttaa ctaaaaatta ttgtatgtta tctcccttaa
      181 ttaggaatga taagggaata actagaaaga tttgtgaata caaactattt ctgatataca
      241 aaatatacag taataatgaa tgatgggaga tgggatgaaa gaatttcaat ttgagagaaa
      301 gcagcgtttt tctttgaggc catatgcaat aggagcttgt tcggtcttgc taggaacgag
      361 tttatttttt gctggtatgg gtgctcagcc tgtacaggat acagaaacga gttcagcact
      421 aatttcaagt cattatttgg atgagcagga tttatctgaa aagctgaaat ctgagttgca
      481 atggtttgaa ttagaaaaca agcttttgaa cttatgggag cattaggtta ctatgaagga
      541 tttgttcctt atgtttcaaa tcaatacaaa aaccaagctg aagaagaagg caaaccgcta
      601 tctgataaat atattttcga aaaaatctta ggaaaaacat atgcagcctt caaaaaagat
      661 caaattaatg agcgtgtcga gaaattaggt aagttaaaac ctattacaat aaattacaac
      721 ggaaaatcag aagtaattga tagtaaagaa aaattacaag agcttatgaa taaagccgtt
      781 aaagacgaag tggctcaaat atagtaaaat gaaataagaa caggataaat cgatcaggac
      841 agtcaaatcg atttctaaaa atgttttaga agtagaggtg tactattcta gtttcaatat
      901 actataaaat caggcaatac cacggctaaa aagtttgagt ttatcgaaac accagtgcaa
      961 aaactgaaaa aagcgattta taaagctcat ctcaaagatt cagat
//
LOCUS       DBEJKC010000122          999 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.122, whole genome shotgun sequence.
ACCESSION   DBEJKC010000122 DBEJKC010000000
VERSION     DBEJKC010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..999
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.122"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..177)
                     /locus_tag="ACL3G6_002048"
     CDS             complement(<1..177)
                     /locus_tag="ACL3G6_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HGR0546499.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNL"
     gene            complement(190..939)
                     /locus_tag="ACL3G6_002049"
     CDS             complement(190..939)
                     /locus_tag="ACL3G6_002049"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HGR0546500.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
BASE COUNT          342 a          194 c          114 g          349 t
ORIGIN      
        1 taagttattc tcgcaaaaaa acttcataag ctcttcattt ttagatggaa gaatgccctt
       61 ttttaaatta tttattttta cagaatctat atcatatgca acaactttat atttagatgc
      121 aaatagtaac gcgtaggcca gcccaacatg ccccaaacca attactgcta tattcataaa
      181 actacttcct tatttcttaa tccaaaatct aatagaataa gctgccccat tccttaaata
      241 caactcttta atattgttta aaagtttttc aactgatttc cagattatca aaatctgaga
      301 tttatagcac aatattgatg atattctatc aatataatgt ttttcatcaa gttcctcttg
      361 atacattttt aattctttag tttttcccat ataactaacc atactactat cacttacata
      421 tgggaagtcc tcataatata ttactttata acgcataaat tcaagcgccc ttccaatact
      481 attcacaaaa acatgatcaa catggtcacc aagtgaaagc ggacaatata cgacacattt
      541 gtcgtctaaa tgcattaaca gctcttttat gatatcattc tttaatgtgt cctcattttt
      601 taattcacta tagatatgac ggtatagaaa attgccattt ctatctttcc tatagagaca
      661 ttcatagtac gataagtgtc taaaatcaca ctgtagacgt tcacaagcta acctgtcttc
      721 tttcttcctt tcttcaatcg gatatttccc aaggttacac aacttatgaa attgcttagc
      781 agagggctgt agctgttggc tcaaagggta accagaaaat atagtaataa caagtacaat
      841 ttctccttct gaagttaatt ttgaaatata atcaccacag gaaaaaattg cgtcatctaa
      901 atgtggagat aaaaatatat acttagtatt gttactcata accattccct ctacaattta
      961 tctaaaaatt cactaagtgt ctgattaaat tccacatca
//
LOCUS       DBEJKC010000123          944 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.123, whole genome shotgun sequence.
ACCESSION   DBEJKC010000123 DBEJKC010000000
VERSION     DBEJKC010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..944
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.123"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..112
                     /locus_tag="ACL3G6_002050"
     CDS             <1..112
                     /locus_tag="ACL3G6_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HGR0546501.1"
                     /translation="IKIKLPIDSRGTPDWNYMERYIEDLKLKCNIANYNI"
     gene            168..485
                     /locus_tag="ACL3G6_002051"
     CDS             168..485
                     /locus_tag="ACL3G6_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HGR0546502.1"
                     /translation="MMASKRLSIEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNK
                     RLIEKGAVFESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKD
                     EIT"
     gene            795..>944
                     /locus_tag="ACL3G6_002052"
     CDS             795..>944
                     /locus_tag="ACL3G6_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HGR0546503.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     RKEKIL"
BASE COUNT          436 a          116 c          162 g          230 t
ORIGIN      
        1 tatcaaaatt aaattaccga tagacagtag aggtactcca gattggaatt acatggaaag
       61 atatatagaa gacttaaaat taaaatgcaa tatagcaaat tataatattt aaaacaagaa
      121 cgattagaaa taaaaatcta gtcgtttttt attttaagaa aggatacatg atggcaagta
      181 aaagattaag tattgaagaa cagattgaaa agaaagaaga aagcattaag caattacaaa
      241 atcaaaaaag acagttgaag aaaaaactta atgaacaaga aagaaaagca agaaacaaaa
      301 gacttataga aaaaggtgca gtgtttgaaa gtatttttga agaaagtatt gatttaacaa
      361 aagatgaatt ttataagtta ataaaaacgt taaatgatga agaaataaga ttaaacataa
      421 tggaaatttt agaagaaaga atagatgata atgtagaaaa atcatctaaa gatgaaataa
      481 cataattgtc ccttggttac aagggcgcaa ttatacaccc taaagggtgc ttgcgtcctg
      541 cggagtcaaa cccttgcagg gagcaacaac cattcgcttt ttaaaagtca agggtaaata
      601 aactcgctaa ggctcgccct tgacttttaa aatttgaaat gaaagtaaca attaagccaa
      661 catactgaaa caacaaaaat taattcagta gtcggctttt ttaattctat catttcaaaa
      721 cgctcattca caaagaggat ataaaaaaac tattaagcct ccacctaaaa caacaaagaa
      781 aggaagtgat aaaaatggca gacagttttc atttttcagt aaacataata tcaagaggaa
      841 aaggcaaaag tgcagtagca agtgcagcat atataagtgg agaaaaaata aaaaatgaat
      901 gggacggagt aacccatgac tacacaagaa aagaaaaaat atta
//
LOCUS       DBEJKC010000124          941 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.124, whole genome shotgun sequence.
ACCESSION   DBEJKC010000124 DBEJKC010000000
VERSION     DBEJKC010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..941
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.124"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            69..935
                     /locus_tag="ACL3G6_002053"
     CDS             69..935
                     /locus_tag="ACL3G6_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0546504.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEEVNELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKFYMEWIKSLIDFYFYGQKEEAITRLENMLPQLNVSDLNYLQVSNTLFN
                     FYYDIEDLERFNEIRDKLEHQVNQLNLNTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKEYRTTYLLADLYLLMGSVSENFSSKSSVKEYFETAHFLYKLEENMSMA
                     LKVEHYFADITE"
BASE COUNT          358 a          117 c          173 g          293 t
ORIGIN      
        1 tatttgaaat ttagatttaa tcatgttaca attaacattg aaatcaaata gaaaaggaag
       61 atgcaaacgt gggtacacta ttagcaacaa gattaaaaaa tagacgaaaa gaattaaaaa
      121 tgtctcagcg agaattagct gagggtatct gtaaacaggg gcaaattagt cgattagaga
      181 gtggagagtt cacccctgga gcggattttt tacatgccct tgctaagaaa ttaaaagtta
      241 gtatggacta cttttttgat gagcaggttg tagaggaagt caatgagtta tcagagttta
      301 agaagttagc acagacattt atcacaaatc gtaattatga atctttaaaa tatatatatg
      361 aattggaaaa tgtaaaagcc catcgcttat ctctagcaga taaattttac atggaatgga
      421 taaagtctct tatagatttt tatttttatg gacagaaaga agaggcaatt acacgattag
      481 agaatatgct acctcagtta aatgtatctg atttgaacta ccttcaagtt tcaaacactc
      541 tattcaattt ttattatgat attgaagatt tagaacgttt taatgagatt agagacaagc
      601 tagagcatca agtgaatcag cttaatttaa acacaattga agagttagaa ctatcaatta
      661 agttcaatta taacgtttgt cgatacctat ggttacagaa aaatattgaa gaagctatta
      721 cgaaaatcac agctacgata aagcaatgta aggagtacag gacaacttat ctattagctg
      781 atttgtattt attgatggga agtgtaagtg aaaatttttc ttctaaaagt tcagtaaaag
      841 aatattttga gactgctcat tttctctaca aacttgagga aaacatgtca atggctttga
      901 aagtcgaaca ttattttgca gatataacag aataaggaat a
//
LOCUS       DBEJKC010000125          918 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.125, whole genome shotgun sequence.
ACCESSION   DBEJKC010000125 DBEJKC010000000
VERSION     DBEJKC010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..918
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.125"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            300..918
                     /locus_tag="ACL3G6_002054"
                     /pseudo
     CDS             300..918
                     /locus_tag="ACL3G6_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT          309 a          154 c          185 g          270 t
ORIGIN      
        1 aaaagtgttt tgatggtttg gatttcttct ttagttgatt tcatatcact attgtataat
       61 gctttttgat tttagtctag tataaatagc gagaaatatc tatcctatct tctagaatgt
      121 cttccaaacg aggaaactct cgtaaacaaa gaggttttag aggcctattt accgtggact
      181 aaagttgtac aagaaaagtg caaataagaa atctccagat taggaactat ccgtgagttc
      241 tctagtctgg agatttttca atagacttcc tgcgaaacaa aatatggtat aatagttcta
      301 tgaattatga agcaagtaaa caactaaccg atgcacgatt taagcgtctt gttggtgttc
      361 aacgcacgac ttttgaagag atgttagctg tattaaaaac agcttatcaa cttaaacacg
      421 caaaaggtgg gcgaaaacct aaattaagcc tagaagacct tcttatggcc actcttcaat
      481 atgtgcgaga atatcgaact tatgaagaaa ttgcggctga tcttggtatt cacgaaagca
      541 acttaatccg tcggagccaa tgggttgaag taactcttgt tcaaaggtgg tgttgcgatt
      601 tcaagaactc ctctcagttc tgaggacacg gtaatgattg atgcgacgga agtaaaaatc
      661 aatcgaccta aaaaaagaat tagcgaatta ttctggtaaa aagaaatttc acgctatgaa
      721 gactcaagcg attgtcacaa gtcaagggag aattatttct ttggatatcg ctgtgaacta
      781 ttgtcatgat atgaagttgt tcaaaatgag tcgcagaaat atcggacaag ctggtaaaat
      841 cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac aaacttcacg
      901 taaatccagc aaactcaa
//
LOCUS       DBEJKC010000126          793 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.126, whole genome shotgun sequence.
ACCESSION   DBEJKC010000126 DBEJKC010000000
VERSION     DBEJKC010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..793
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.126"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..>793)
                     /locus_tag="ACL3G6_002055"
     CDS             complement(<1..>793)
                     /locus_tag="ACL3G6_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0546505.1"
                     /translation="KIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLD
                     DDDEYMSDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMV
                     HNIAGTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHS
                     KENGITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCK
                     ALKVIKKAREEKIFNEFLFLKYMLLYHFGFFYCIYDNYVQLKFRK"
BASE COUNT          267 a          144 c           80 g          302 t
ORIGIN      
        1 cactttctaa attttaattg aacatagttg tcatatatac aatagaaaaa accaaaatga
       61 tataataaca tatatttcaa aaaaagaaat tcgttaaaaa ttttttcttc tcttgccttc
      121 ttgattactt ttaaagcctt gcatttgtct cctattaata gtaaccgctt tatgtttaaa
      181 gaataatatt tctttgtaac caatattctc tcgttgaaac tcaataaatt aaaatatttc
      241 ctacagtaat tataatattc ttcatctgca ttaattgttt tttgtgtcac tccagtgata
      301 ccgttttctt tactgtgagc gtagtaattc accaagaatt ctcgcactat atcaatttgg
      361 tatccttgag caagtagttt taataaaaca acaccgtcct gatgtgaatc tattttctca
      421 aaaccattaa ttaattctag cacctctttt ttacacaacc aaaatgacgt acctgctata
      481 ttgtgaacca tttgaacaaa caagggattt ccaacaaaat cggtcttctc ctcttctcgt
      541 gtaccatttg gataaattat tattccataa ctataaacta aagctaaatt cttcattcta
      601 ctctttttaa aacaagccat caactttaaa attcgatctg acatatattc atcatcatcg
      661 tctaaaaatg atatatactt acctctagaa tttttgatac ctatgtttct ggcattagtt
      721 gcacctaaat cttcattact taaaattaac ttaattctat gattggtata gccaaattga
      781 tggataattt tat
//
LOCUS       DBEJKC010000127          766 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.127, whole genome shotgun sequence.
ACCESSION   DBEJKC010000127 DBEJKC010000000
VERSION     DBEJKC010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..766
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.127"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..>766
                     /locus_tag="ACL3G6_002056"
     CDS             <1..>766
                     /locus_tag="ACL3G6_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0546506.1"
                     /translation="TQEIDVPYDIPDTWEWVRFSTLVEIVRGGSPRPIKDYLTSEVDG
                     INWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGA
                     IHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLP
                     PLSEQQRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDP
                     NDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQ"
BASE COUNT          291 a          106 c          133 g          236 t
ORIGIN      
        1 actcaagaaa ttgatgttcc ttatgatatt cctgatactt gggagtgggt gaggttttct
       61 acattggttg aaattgtcag aggtggctct ccacgaccaa tcaaagatta tcttacttct
      121 gaagtagatg gaataaattg gataaaaata ggtgatactg aaaagggtga aaagtatata
      181 aataatgtta aagaaaaaat caaaaaatca gggcttaaca aaactagatt tgtaaaaaaa
      241 ggtacatttt tgttaactaa ttctatgagt tttggtagac cttatatttt gaatgttgat
      301 ggtgcaatac acgatggatg gttggctatt tcgaactatg aaaactcatt aaataaagat
      361 tatctattct atattctttc atcaaatgta gtttattctc aatttctatc tctaattagt
      421 ggagctgttg tgaaaaactt gaatagtgat aaagttgctt ctattcttat ccctctcccc
      481 ccactatccg aacaacaacg cataatagaa gcaatcgaat cagctttaga aaaagtagat
      541 gaatatgctg aaagttataa tagactagaa cagctagata aagaatttcc agataaacta
      601 aaaaaatcta ttcttcaata tgctatgcaa ggaaaattag ttgaacaaga cccaaatgat
      661 gaatcagtcg aagttttact tgaaaaaata cgagcagaaa aacaaaaact ctttgaagaa
      721 ggcaagatta aaaagaaaga tttggacatt tctattgttt cccaag
//
LOCUS       DBEJKC010000128          707 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.128, whole genome shotgun sequence.
ACCESSION   DBEJKC010000128 DBEJKC010000000
VERSION     DBEJKC010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..707
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.128"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(301..546)
                     /locus_tag="ACL3G6_002057"
     CDS             complement(301..546)
                     /locus_tag="ACL3G6_002057"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGR0546507.1"
                     /translation="MAESIQGWLAQFLVNLFKSITFDCGKEFSKWKDISNHHDSESFF
                     ANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
BASE COUNT          219 a          125 c          121 g          242 t
ORIGIN      
        1 ataatttatt tcatattttg taaggtcagt gtgaaaatat ttaaatagac ttcctgtaaa
       61 aactggattt aacgccctcc atttgtcaaa ttaagctaga cagtcttacc aactcagaaa
      121 atacctgatg aggtatttgg tatccaaagg atttaggtgg gatgtgattt cttgaggctg
      181 ggaaaaagtc tttaaaatta aaaaatgtat aatatcaggt gttggaaaaa ctttgatact
      241 atgcgtttta ttgtgggaat atttatttca ttttctcctg aaattgagtt tttacccagc
      301 ctaaaattct tgactgactt cgttgaaatc tgtctgcttt ggcaagtcat gacaccttaa
      361 aagtctattt gaatgttcgt tgagacaccg ctgtcttgga catcctagat tcgcaaaaaa
      421 gctctcacta tcgtgatgat tggaaatatc tttccatttt gaaaactctt ttccacagtc
      481 aaacgtaata gatttaaaga ggttcactag aaattgtgcc agccaccctt ggatggattc
      541 tgccatatcc tttgccttac gactcttggt cttcaaactg acaatcaatt gactatacct
      601 gttcgctcac aaataggaga gaacttttta cgaaaatcta atgaatatgc cacaagaaca
      661 ttataccgca acgtgtacta tttttggttc attttactat agaaact
//
LOCUS       DBEJKC010000129          698 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.129, whole genome shotgun sequence.
ACCESSION   DBEJKC010000129 DBEJKC010000000
VERSION     DBEJKC010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..698
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.129"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            80..>698
                     /locus_tag="ACL3G6_002058"
     CDS             80..>698
                     /locus_tag="ACL3G6_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HGR0546508.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KRTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENY"
BASE COUNT          278 a           87 c          137 g          196 t
ORIGIN      
        1 aaaaatggtt accaaaggcg atagaagaaa aactatcgtc tttttctttg caaattttta
       61 agaagggagg tgatcttgca tggactttga atatttttat aacagagaag cggaaagatt
      121 taacttctta aaagtaccgg agatattagt tgatagagaa gaatttcggg gcttatcagc
      181 agaagcaatt atcctttatt ccatacttct taaacggaca ggaatgtcat ttaagaataa
      241 ctggatagac aaggaaggca gagtatttat ctattttact gtcgaagaaa ttatgaaaag
      301 aagaaatatc tcaaagccaa ctgccataaa aacattagat gagcttgatg taaaaaaagg
      361 aataggactg atcgaaagag taaggcttgg acttggtaag ccgaacatca tttatgttaa
      421 agactttatg agtatatttc aggtaaaaga aaatgactta cagaagtcaa aaaacttaac
      481 ttcagaagta aaagatttta acctcagaag taaagaaaat gaacttcaag aggttaagaa
      541 ccttgactct aactatatag agaataataa gagtaagtat agtaagagag aatatagctt
      601 tggtgaaaac ggacttggaa catttcaaaa tgtgttttta gctgctgaag atatatcgga
      661 tttacaaatc ataatgaact cacagcttga gaattaca
//
LOCUS       DBEJKC010000130          698 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.130, whole genome shotgun sequence.
ACCESSION   DBEJKC010000130 DBEJKC010000000
VERSION     DBEJKC010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..698
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.130"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..>698
                     /locus_tag="ACL3G6_002059"
     CDS             <1..>698
                     /locus_tag="ACL3G6_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0546509.1"
                     /translation="LLSDPNREQFQHDNRQVDLKILARHIHRLKKKQSDWKVQYTRCL
                     DIIFPELDKIVGKHSEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTASKIQDILSVAP
                     RSIGTTSPAREFEIIEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGGRLGAVIL
                     AEIRNIHAFDNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLRWALIQAAKACAR
                     FSPAFKAYLKTKLE"
BASE COUNT          206 a          154 c          141 g          197 t
ORIGIN      
        1 aacttctttc tgaccccaat cgtgaacaat ttcaacacga taatcggcaa gtagacctaa
       61 aaatactggc tagacatatt catcgtctca agaaaaaaca gtctgattgg aaagtacaat
      121 acactcgttg tcttgatatc atctttcctg agttggataa aatcgttgga aagcattcag
      181 aatataccta ccaactcttg acgcgctacc ctaatcctca gaaaaggatt gaggcaggat
      241 ttgataagct gatagaaatt aagcgattga ccgcttctaa aattcaggat atcctctcag
      301 tcgcacctcg ttctatcgga acaacatctc ctgctcgtga attcgaaatc atcgaaatca
      361 tcaaacatta caagaggctc attgacaagg cggaaacatg tgtcaatgac ttgatggctg
      421 agttcaactc agtcatcacg acggttactg ggattggggg tcgtttaggg gcggtcattt
      481 tagccgagat tcgaaatatt catgcctttg ataatcctgc tcaattacaa gctttcgctg
      541 gactggattc ttctatttat cagtcaggtc agattgattt agctggaaga atgatcaaac
      601 ggggttcccc tcatctgcgg tgggcactca tacaagctgc caaagcatgc gctcgctttt
      661 cacctgcttt taaggcctat cttaagacta agttagaa
//
LOCUS       DBEJKC010000131          690 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.131, whole genome shotgun sequence.
ACCESSION   DBEJKC010000131 DBEJKC010000000
VERSION     DBEJKC010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..690
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.131"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(72..145)
                     /locus_tag="ACL3G6_002060"
     tRNA            complement(72..145)
                     /locus_tag="ACL3G6_002060"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(109..111),aa:Arg,seq:acg)
     gene            complement(155..240)
                     /locus_tag="ACL3G6_002061"
     tRNA            complement(155..240)
                     /locus_tag="ACL3G6_002061"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(204..206),aa:Leu,seq:taa)
     gene            complement(248..319)
                     /locus_tag="ACL3G6_002062"
     tRNA            complement(248..319)
                     /locus_tag="ACL3G6_002062"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(285..287),aa:Gly,seq:gcc)
     gene            complement(342..414)
                     /locus_tag="ACL3G6_002063"
     tRNA            complement(342..414)
                     /locus_tag="ACL3G6_002063"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(379..381),aa:Thr,seq:tgt)
     gene            complement(433..514)
                     /locus_tag="ACL3G6_002064"
     tRNA            complement(433..514)
                     /locus_tag="ACL3G6_002064"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(478..480),aa:Leu,seq:tag)
     gene            complement(520..592)
                     /locus_tag="ACL3G6_002065"
     tRNA            complement(520..592)
                     /locus_tag="ACL3G6_002065"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(557..559),aa:Lys,seq:ttt)
     gene            complement(617..689)
                     /locus_tag="ACL3G6_002066"
     tRNA            complement(617..689)
                     /locus_tag="ACL3G6_002066"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(654..656),aa:Asp,seq:gtc)
BASE COUNT          180 a          203 c          148 g          159 t
ORIGIN      
        1 aacctgcgac accttggtcc caaaccaagt actctaccaa gctgagctac ttcccgagtt
       61 aaaaagaaaa atgcacccta gaggagtcga acctctaacc gcctgattcg tagtcaggta
      121 ctctatccag ttgagctaag ggtgctccat attatgccga ggaccggaat cgaaccggta
      181 cgatcgttac caatcgcagg attttaagtc ctgtgcgtct gccagttccg ccaccccggc
      241 ctctctaagc gaacgacggg attcgaaccc gcgaccccca ccttggcaag gtggtgttct
      301 accactgaac tacgttcgca ctgttttctt ctatctaaaa atgccggcta catgacttga
      361 acacgcgacc ctctgattac aaatcagatg ctctaccaac tgagctaagc cggctcattt
      421 gttatatctt aatgcgggtt aagggacttg aacccccacg ccgttaagcg ccagatccta
      481 aatctggtgc gtctgccaat tccgccaaac ccgcatatat gacccgtact gggctcgaac
      541 cagtgaccca ttgattaaaa gtcaattgct ctaccaactg agctaacgag tctaaaataa
      601 cttgcgttat cttaaacggt cccgacggga atcgaacccg cgatcttcgc cgtgacaggg
      661 cgacgtgata accgctacac tacgggacct
//
LOCUS       DBEJKC010000132          662 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.132, whole genome shotgun sequence.
ACCESSION   DBEJKC010000132 DBEJKC010000000
VERSION     DBEJKC010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..662
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.132"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            77..439
                     /locus_tag="ACL3G6_002067"
     CDS             77..439
                     /locus_tag="ACL3G6_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HGR0546510.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
BASE COUNT          220 a           81 c          121 g          240 t
ORIGIN      
        1 aacttcaaaa cagtgttttg agcaacctgc ggctagtttc ctagtttgct ctttggtttt
       61 cattgagtat aacagattgt tagaagttgg tttaaatttc ctaatcagtt tgttcacatt
      121 taccttcgat atattatatc ccatagttaa ggttggtcat acagatgatt atagtcatgg
      181 agccgtaaaa cttagtgttt ctttagttga caaagatgcc atgaaaaaaa tatctgtaac
      241 tgtaatagga tattttgaaa taaatataga tgaaaatatc accgatattc tatacgtaaa
      301 tggtactgct attctttatc attatttacg ttctattgtt tcaatagttt cggcaattga
      361 tagcagtgaa gcaatgttgc tacctaccat taatgtttta gagttactag ataaatctca
      421 accttttgaa gaagaataat ttattagctc actaaattga gggtaaggaa aagtaaaatc
      481 agtaagaaaa atgtcttgca ttatacagca accttttggg aatgagtaga tggattgaat
      541 aaaattttat taagagtgga tgatttatct gtagattatt attggacagt tagtcttgaa
      601 gtagtctaag aattaggtta taatcagtag aatccttgct aataatgagg aggttagttt
      661 at
//
LOCUS       DBEJKC010000133          640 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.133, whole genome shotgun sequence.
ACCESSION   DBEJKC010000133 DBEJKC010000000
VERSION     DBEJKC010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..640
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.133"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..177
                     /locus_tag="ACL3G6_002068"
     CDS             <1..177
                     /locus_tag="ACL3G6_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0546511.1"
                     /translation="DKEVEVSLLFFIINNSSSSQTNILAQLMNFFTGNGHLEDLSKIS
                     EPEKLYAYIDEAIA"
     gene            215..517
                     /locus_tag="ACL3G6_002069"
     CDS             215..517
                     /locus_tag="ACL3G6_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0546512.1"
                     /translation="MIKILAACGAGVNSSHQIKSTLEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSAPVFDNIRLPAKQNMV"
     gene            525..>640
                     /locus_tag="ACL3G6_002070"
     CDS             525..>640
                     /locus_tag="ACL3G6_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HGR0546513.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQL"
BASE COUNT          216 a          117 c          118 g          189 t
ORIGIN      
        1 gataaggaag tagaagtatc cctactcttc tttatcatta ataattcaag ttcaagtcaa
       61 acgaacattc ttgctcagtt gatgaacttc ttcacaggaa atggacatct tgaagaccta
      121 tcaaaaattt ccgaaccaga aaaactttat gcttatatag atgaagcaat cgcttaatct
      181 tgtctattaa aaaataaaat cggaggaagt ctatatgatt aaaattcttg ctgcctgcgg
      241 tgcaggtgtt aactcaagtc accaaattaa aagtactcta gaagaagaac tttcaaaccg
      301 tggttacgat gttcactgtg atgcagtcat ggtgaaagat gtaaacgaag accttatgaa
      361 aggttacgat atctttacac caatcgctgc aacagatctt ggttttgaac caggtatccc
      421 agttatcgaa gctgggccaa tcttattttg tatcccagca atgagcgctc cagtatttga
      481 caatattaga ctccctgcga aacaaaatat ggtatagtag ttctatgaat gatgaagcaa
      541 gtaaacaact aaccgatgca cgatttaagc gtcttgttgg tgttcagcgt accacttttg
      601 aagagatgtt agctgtatta aaaacagctt atcaacttaa
//
LOCUS       DBEJKC010000134          635 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.134, whole genome shotgun sequence.
ACCESSION   DBEJKC010000134 DBEJKC010000000
VERSION     DBEJKC010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..635
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.134"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(1..69)
                     /locus_tag="ACL3G6_002071"
                     /pseudo
     CDS             complement(1..69)
                     /locus_tag="ACL3G6_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014025385.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(304..615)
                     /locus_tag="ACL3G6_002072"
     CDS             complement(304..615)
                     /locus_tag="ACL3G6_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHY zinc finger protein"
                     /protein_id="HGR0546514.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
BASE COUNT          213 a          114 c          100 g          208 t
ORIGIN      
        1 catatcgtaa aggtcgtatt tccaacggca tgactgagaa catccaccac ggttggcatc
       61 acgcatactc tagacgcaat tctaatcttt tagactttgc ataataactg ttaaacagtt
      121 gaaaattaac ccagttttaa caagtagtca aaataccaga taaaggaaaa aagtctttaa
      181 aatcttaaaa acgcatagta tcaggtattg aacaatcttg atattatgcg ttttattgtg
      241 ggaagattta cttcattttc tcttggaatt gagttttctc ctacttcaaa actagatgat
      301 ttgctattta aaatagcgtt ccttatgatt ttggcaacct ggattaaagc gagaaaaaca
      361 aaaggggcaa cttaagcttt ctttatattg cttatatgtt agtagtttta gacaaacacc
      421 acataaaata ggcttatcct gtatcaaaga taagggatac ggctcaaaag ggtgattttc
      481 taatgaatca tgacaccgat aacaagcata atacttttta caatcatagc attgtaaagc
      541 aataatatcc agcttgctat ggtaatgaat gcatcttgtt tgcttatcca ctaagaaacc
      601 ctgtgcctct atcatttcct tttcctttct taagc
//
LOCUS       DBEJKC010000135          610 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.135, whole genome shotgun sequence.
ACCESSION   DBEJKC010000135 DBEJKC010000000
VERSION     DBEJKC010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..610
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.135"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..>610
                     /locus_tag="ACL3G6_002073"
     CDS             <1..>610
                     /locus_tag="ACL3G6_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HGR0546515.1"
                     /translation="LQGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHY
                     VSTVTNCYKAAVDAYLESPEKFEAIKQDLVDEMWKVAQRELATGFYYGTPSENEQLFG
                     ARRKIPEYKFVAEVVSYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDA
                     KGNKIDRAPNPMELLTIKVPQPVQSGDMVRALKEGLINLYKE"
BASE COUNT          190 a          114 c          141 g          165 t
ORIGIN      
        1 gtttgcaggg tgagattcca gaagaatttt caatgtcagc cgttgacatg tctatgattg
       61 accacattcc agatatgatt gaaaatggtg tggacagtct aaaaatcgaa ggacgtatga
      121 agtctattca ctacgtatca acagtaacca actgctacaa ggcggctgtg gatgcctatc
      181 ttgaaagtcc tgaaaagttt gaagctatca aacaagactt ggtggacgag atgtggaagg
      241 ttgcccaacg tgaactggct acaggatttt actatggtac accatctgaa aatgagcagt
      301 tgtttggtgc tcgccgtaaa attcctgagt acaagtttgt cgctgaagtg gtttcttatg
      361 atgatgcggc acaaacagca acaattcgtc aacgaaatgt cattaacgaa ggggaccaag
      421 ttgagtttta tggtccaggt ttccgtcatt ttgaaaccta tattgaagat ttgcatgatg
      481 ccaaaggcaa taaaatcgac cgcgctccaa atccaatgga actattgact attaaggtgc
      541 ctcaacccgt tcaatcagga gacatggttc gtgcattaaa agaaggactc atcaatcttt
      601 ataaggaaga
//
LOCUS       DBEJKC010000136          608 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.136, whole genome shotgun sequence.
ACCESSION   DBEJKC010000136 DBEJKC010000000
VERSION     DBEJKC010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..608
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.136"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..260)
                     /locus_tag="ACL3G6_002074"
     CDS             complement(<1..260)
                     /locus_tag="ACL3G6_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0546516.1"
                     /translation="MIEVSHLSKSFGDKIALNNISFTVKEGQIFGFLGPSGSGKTTTI
                     NILTGQFLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFY"
BASE COUNT          231 a          111 c           55 g          211 t
ORIGIN      
        1 tcataaaatc cacttgtatc gctaaccaat ccaattctct ttaattcacc gcttgttaaa
       61 ttttgagatt tttgtcccaa aataatagat tgtcctttat cggcaaggaa ctgcccagtc
      121 agaatattaa tcgttgtggt ttttccagaa ccagatggtc ctaaaaatcc aaaaatctga
      181 ccttctttaa cagtgaagct tatattattt aaagctattt tatcaccaaa actttttgat
      241 aaatggctaa cttcaatcat actcattgca cctcctttat attctacatt tttacttaac
      301 atctatttac ttagctttat caaataaacg tcttaaaaaa aacaataaca ttaagcatat
      361 aaccgttagc aagattgttt caatattatt gataatatga tacattctca agcagtataa
      421 aataattata tatatgcaaa tgctcattat acctattttt ttaaacatac taagcctcct
      481 tgccaaataa taaagttata taataactaa gacacactat acctaacata ataaatatcc
      541 acagcattaa aaatattatc atacaaataa aaatatccac tggtaactga ataaatgttc
      601 taaaatta
//
LOCUS       DBEJKC010000137          605 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.137, whole genome shotgun sequence.
ACCESSION   DBEJKC010000137 DBEJKC010000000
VERSION     DBEJKC010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..605
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.137"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            408..569
                     /locus_tag="ACL3G6_002075"
     CDS             408..569
                     /locus_tag="ACL3G6_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0546517.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQDMKNSFD
                     MAKTQIETD"
BASE COUNT          236 a           84 c          113 g          172 t
ORIGIN      
        1 aattttgtta catcaagata aatattttct gatggtcaaa ttttaaaaag attaataact
       61 ctcgataaat tttgaacctt aacaattgaa tagaccaaga caagacgtta attatttttt
      121 gagcgtaata acctatccgt caagatcttt cggctgaata attcggcaaa aaaagttctg
      181 ctaagcaaaa agaaagtgag cgataagtaa gagtttgaat atagggaggg ataccctatc
      241 cgctatgaag aaaatgagga taatgatact tctaaggttg aagccggctc atccggaata
      301 gaggcggagg tgagattcct atgttgctaa tccaaagcac ttgtcaatgt caaaaaactt
      361 aattaaacaa ataattatta gatataaaac tttagaggag gtatatattg gacaatgact
      421 ggaatggatt ggctgattta atagcaaatc tgattgcaaa atatgctggt gctttagatt
      481 tagataatct acccgatcca acgccagcaa aaaatcaaga tatgaaaaat agttttgaca
      541 tggcaaaaac acaaattgag acggactaat aaaagtgtta taatatactt gaaatgatag
      601 tccaa
//
LOCUS       DBEJKC010000138          587 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.138, whole genome shotgun sequence.
ACCESSION   DBEJKC010000138 DBEJKC010000000
VERSION     DBEJKC010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..587
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.138"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..587
                     /locus_tag="ACL3G6_002076"
                     /pseudo
     CDS             1..587
                     /locus_tag="ACL3G6_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          231 a           96 c          118 g          142 t
ORIGIN      
        1 aattgattga tcgttacgga atagagttcg tcaaaaaagg aaaaaatcgt tactattctc
       61 ctgatttaaa acaagaaatg attcataaag tctgacatga aggctggact aaagatagag
      121 tttctcttga atacggcctc ccaagtcgta cgatacttct taactggcta gcacaataca
      181 ggaaaaacgg gtatactatt gttgagaaaa caagagggag agtacctaaa atgggacgta
      241 atccaaaaac gagacctgaa gagaggacag aattagaacg tcttcaagca gaaaatgagt
      301 acctgagagc ggagaatgcc atcctaaaaa agttaagaga actccgattg aaggaggaaa
      361 aagagaaaga agaaagacag aaattgttca agaattaatg actgagtttt cgttagatct
      421 tcttctaaaa tccattaaac tagctcgttc gacctactac tatcacttga aacagctaga
      481 caaaacagat aaggaccaag agcttaaagc tgaaattcaa tccattttta tcgaacacaa
      541 gggaaattat gcttatcgtc gaatttattt agaactaaga aatcgtg
//
LOCUS       DBEJKC010000139          504 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.139, whole genome shotgun sequence.
ACCESSION   DBEJKC010000139 DBEJKC010000000
VERSION     DBEJKC010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..504
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.139"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..>504
                     /locus_tag="ACL3G6_002077"
     CDS             <1..>504
                     /locus_tag="ACL3G6_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HGR0546518.1"
                     /translation="HDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKEYILDEKGEK
                     VLNKNGKPKTRKVELTTWNDTGNVEKWRENFSDLCNKYLERAGAEKRVDHRSFKRQNS
                     DYLPTIHLGSAASAMERKGIETDKGNYNREIRKYNQLVKTIKEEIKTLKGWIGNLLDN
                     LSTAYEK"
BASE COUNT          246 a           58 c           94 g          106 t
ORIGIN      
        1 tcatgatgag agtcaagata aaaatggaaa tatccattgt catataatga ccataatgcg
       61 accaataaac gaaaaaggag agttcttagc caagtcaaaa aaagaatata tcctagatga
      121 aaaaggagaa aaagtattaa acaaaaatgg aaaaccaaag acaagaaaag tagaactaac
      181 aacctggaac gatacaggca atgtagaaaa atggagagaa aatttttcag atctttgtaa
      241 caaatattta gaaagagcag gagcagaaaa aagagtagac cataggagtt ttaaaagaca
      301 aaattcagat tatctaccga caatccattt aggatcagca gcaagtgcaa tggaaagaaa
      361 gggaatagaa actgacaagg gaaactataa tagagaaata agaaaatata atcaacttgt
      421 aaaaacaata aaagaagaga taaaaacatt aaagggttgg ataggaaatt tattagataa
      481 cttatctact gcttatgaaa aatt
//
LOCUS       DBEJKC010000140          499 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.140, whole genome shotgun sequence.
ACCESSION   DBEJKC010000140 DBEJKC010000000
VERSION     DBEJKC010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..499
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.140"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..>499
                     /locus_tag="ACL3G6_002078"
     CDS             <1..>499
                     /locus_tag="ACL3G6_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HGR0546519.1"
                     /translation="EIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIK
                     KDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMP
                     YNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPN
                     ERPHS"
BASE COUNT          161 a          104 c          113 g          121 t
ORIGIN      
        1 atgagattca agtagccaag ttggcaggca agtacacaac agaagacggt tatatctttg
       61 atcctcgtga tataaccagt gatgaggggg atgcctatgt aactccacat atgacccata
      121 gccactggat taaaaaagat agtttgtctg aagctgagag agcggcagcc caggcttatg
      181 ctaaagagaa aggtttgacc cctccttcga cagaccatca ggattcagga aatactgagg
      241 caaaaggagc agaagctatc tacaaccgcg tgaaagcagc taagaaggtg ccacttgatc
      301 gtatgcctta caatcttcaa tatactgtag aagtcaaaaa cggtagttta atcatacctc
      361 attatgacca ttaccataac atcaaatttg agtggtttga cgaaggcctt tatgaggcac
      421 ctaaggggta tactcttgag gatcttttgg cgactgtcaa gtactatgtc gaacatccaa
      481 acgaacgtcc gcattcaga
//
LOCUS       DBEJKC010000141          480 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.141, whole genome shotgun sequence.
ACCESSION   DBEJKC010000141 DBEJKC010000000
VERSION     DBEJKC010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.141"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..>480
                     /locus_tag="ACL3G6_002079"
     CDS             <1..>480
                     /locus_tag="ACL3G6_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0546520.1"
                     /translation="PCAKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRY
                     WKLIQQDSRKLSDKRFYRPTFRIHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNK
                     DPEKFFGLIEDNLKQVHPIFQTVFKTFLKNKEKIVNALQLPYSNAKLEATNNLIKLI"
BASE COUNT          162 a          105 c           66 g          147 t
ORIGIN      
        1 ttccgtgtgc taaaatcgtt ctagatcgtt tccatattat ccaacatctc agccgtgcca
       61 tgagtcgttt tcgtgttcaa attatgaatc agtttgaacg aaaatctcat gaatacaagg
      121 ctatcaagcg ttactggaaa ctcatccaac aggatagtcg taaactcagc gataaacgtt
      181 tttatcgccc tacttttcgc atacacttaa caaataaaga aattcttgac aagattttaa
      241 gctattcaga agacttgaaa caccactatc agatctatca actcttactt tttcactttc
      301 agaacaaaga ccctgagaaa tttttcggac tcattgagga caatctgaag caggttcatc
      361 ctatttttca gactgtcttt aaaacctttc taaagaacaa agaaaaaatc gtcaatgctc
      421 ttcaattacc ttattccaat gcaaaattgg aagcgaccaa taatctcatc aaacttatca
//
LOCUS       DBEJKC010000142          417 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.142, whole genome shotgun sequence.
ACCESSION   DBEJKC010000142 DBEJKC010000000
VERSION     DBEJKC010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.142"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..>417)
                     /locus_tag="ACL3G6_002080"
     CDS             complement(<1..>417)
                     /locus_tag="ACL3G6_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0546521.1"
                     /translation="ILPHSAYSETLYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTN
                     MTSGTSQDQFQLYRGRGQAENFIKEMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYL
                     FLKHLAGGDFQTLTIKRFRHLFLHVVGKCVRTGRKQL"
BASE COUNT          115 a           87 c           95 g          120 t
ORIGIN      
        1 gagctgcttg cgtcctgttc gaacacattt tcctaccacg tgaagaaaaa gatggcggaa
       61 gcgtttgatt gttaaagttt ggaagtcacc tccagctaga tgtttgagaa aaagatagag
      121 attgtaggcg atacagctca tcatcatacg aacttcgttt ttgattaagg ttgaactatc
      181 cgttttatcg ccaaaaaatc cctccttcat ctccttgatg aaattctcgg cttgaccacg
      241 tccacgataa agctgaaact ggtcttggct tgttccactc gtcatatttg taacgagaga
      301 aataacatcg tagaacaagt ttccttcttt tcgttcagag aactggcaga cacgacgctt
      361 gtgcgaccaa gatcctgctt gatagagagt ttctgagtag gcggagtggg gcaagat
//
LOCUS       DBEJKC010000143          349 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.143, whole genome shotgun sequence.
ACCESSION   DBEJKC010000143 DBEJKC010000000
VERSION     DBEJKC010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.143"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..245)
                     /locus_tag="ACL3G6_002081"
     CDS             complement(<1..245)
                     /locus_tag="ACL3G6_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGR0546522.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRKY"
BASE COUNT           99 a           82 c           43 g          125 t
ORIGIN      
        1 tcgtatttac gcttctgact ttcctgctta cggatatagt ctaaaattcg atttcgaaac
       61 ttggttttga aatatttcct taaacgtgga atatcgtcta ccagtccttc ttctctacta
      121 atcaattcat gtaagcagag catgccttct tggtcccaat ccgataattc ccataaatga
      181 aggtaatatt catttctaca cttatacaca gtcccttgga cttcttcata caattcttta
      241 atcataattt tcccctttct agatacagtc taacagatta gaaaacacat ttgttccatt
      301 ttctccattc tgttcccttt agctcctaaa ctgcacaaaa aagagaggc
//
LOCUS       DBEJKC010000144          320 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.144, whole genome shotgun sequence.
ACCESSION   DBEJKC010000144 DBEJKC010000000
VERSION     DBEJKC010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.144"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..>320)
                     /locus_tag="ACL3G6_002082"
     CDS             complement(<1..>320)
                     /locus_tag="ACL3G6_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0546523.1"
                     /translation="ESFFLRAGGCNTEWMNVFLEELSQAYPDDYFLLVMDNAIWHKSS
                     ILKIPTNIGFAFIPPYTPEMNPIEQVWKEIRKRGFKNKAFRILEDVMNQLQDVIQGLE
                     KEVI"
BASE COUNT          100 a           67 c           49 g          104 t
ORIGIN      
        1 tatcacctcc ttctccagtc cttgtatgac atcttgaagt tgattcatga catcttccaa
       61 aattcgaaag gctttattct taaatccacg tttacgaatc tctttccaca cttgttcaat
      121 ggggttcatc tctggtgtgt atggaggaat aaatgcaaaa ccaatattag tcggaatctt
      181 taagatactt gatttatgcc atatagcatt gtccataacg agtaaaaaat aatcatctgg
      241 ataagcttgt gaaagctctt ctaaaaagac gttcatccac tcagtattac atccaccagc
      301 tcttaagaaa aatgattcgc
//
LOCUS       DBEJKC010000145          268 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.145, whole genome shotgun sequence.
ACCESSION   DBEJKC010000145 DBEJKC010000000
VERSION     DBEJKC010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..268
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.145"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..>268
                     /locus_tag="ACL3G6_002083"
     CDS             <1..>268
                     /locus_tag="ACL3G6_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HGR0546524.1"
                     /translation="ISKNSDIKLTGEEEFWINKWDNFNTKQLIIGRKLDIHLSIVSSI
                     TNVLQIILPVLTLIVGVNIKTFEQLTLGQIVAISTVSPYFISPII"
BASE COUNT           99 a           37 c           39 g           93 t
ORIGIN      
        1 atttctaaaa atagtgatat taagctaact ggagaagagg aattttggat taacaaatgg
       61 gataatttta atacaaaaca gctcatcata ggtcgaaaac ttgatataca tttatcaatt
      121 gttagtagta taacgaatgt tttacaaatt attctccctg ttttgaccct tattgtaggt
      181 gtaaatataa aaacattcga acaattgacg ttaggacaaa ttgtagcaat aagtacagtc
      241 tcaccatact ttatttctcc tataattt
//
LOCUS       DBEJKC010000146          261 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.146, whole genome shotgun sequence.
ACCESSION   DBEJKC010000146 DBEJKC010000000
VERSION     DBEJKC010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..261
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.146"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..>261)
                     /locus_tag="ACL3G6_002084"
     CDS             complement(<1..>261)
                     /locus_tag="ACL3G6_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0546525.1"
                     /translation="VDIDSTHFTTYGKQEGVAYNAHYRAHGYHPLYAFEGKTGYCFNA
                     QLRPGNRYCSEEADSFITPVLERFNQLLFRMDSGFATPKLYD"
BASE COUNT           87 a           52 c           57 g           65 t
ORIGIN      
        1 aatcgtataa ttttggggtc gcaaagccac tatccattcg aaagagaagt tgattaaacc
       61 gttctaaaac aggtgtgata aagctgtctg cctcttcaga acaataacga ttaccaggac
      121 gaagctgggc attgaaacaa taacctgtct tcccctcgaa agcataaaga ggatgatagc
      181 catgagcacg atagtgggcg ttataagcaa caccttcttg cttgccataa gttgtgaaat
      241 gggtagaatc gatatctaca a
//
LOCUS       DBEJKC010000147          233 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC19 isolate 678516
            SAMN38261806-rid24806603.denovo.149, whole genome shotgun sequence.
ACCESSION   DBEJKC010000147 DBEJKC010000000
VERSION     DBEJKC010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261806
            Sequence Read Archive: SRR26833675
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576059.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576059.1
            Genome Coverage       :: 140x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:58:22
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,085
            CDSs (total)                      :: 2,051
            Genes (coding)                    :: 1,916
            CDSs (with protein)               :: 1,916
            Genes (RNA)                       :: 34
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 28
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 67 of 135
            Pseudo Genes (incomplete)         :: 66 of 135
            Pseudo Genes (internal stop)      :: 44 of 135
            Pseudo Genes (multiple problems)  :: 36 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..233
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261806-rid24806603.denovo.149"
                     /strain="GPSC19"
                     /isolate="678516"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..>233
                     /locus_tag="ACL3G6_002085"
     CDS             <1..>233
                     /locus_tag="ACL3G6_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGR0546526.1"
                     /translation="SIEQRPEAINFRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQ
                     IIRLIPNKSAEVVNQALKLILKQHKILSITADN"
BASE COUNT           76 a           48 c           48 g           61 t
ORIGIN      
        1 atccatcgaa cagcggcctg aagctatcaa ttttcgcttg gagaatgggc attatgagat
       61 tgatacggtt ctacttacga gagcgaaaaa ctactgcttg cttgtcttga cggatcgaaa
      121 aagtagacat cagatcatcc gattgattcc aaataaaagt gctgaggtgg tcaatcaggc
      181 tctaaaactc atcttaaaac aacacaagat tctttccatc acggcagata atg
//
